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https://www.readbyqxmd.com/read/28210850/the-laminar-organization-of-the-motor-cortex-in-monodactylous-mammals-a-comparative-assessment-based-on-horse-chimpanzee-and-macaque
#1
Bruno Cozzi, Alberto De Giorgio, A Peruffo, S Montelli, M Panin, C Bombardi, A Grandis, A Pirone, P Zambenedetti, L Corain, Alberto Granato
The architecture of the neocortex classically consists of six layers, based on cytological criteria and on the layout of intra/interlaminar connections. Yet, the comparison of cortical cytoarchitectonic features across different species proves overwhelmingly difficult, due to the lack of a reliable model to analyze the connection patterns of neuronal ensembles forming the different layers. We first defined a set of suitable morphometric cell features, obtained in digitized Nissl-stained sections of the motor cortex of the horse, chimpanzee, and crab-eating macaque...
February 16, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28205309/a-feasibility-study-of-a-deuterium-deuterium-neutron-generator-based-boron-neutron-capture-therapy-system-for-treatment-of-brain-tumors
#2
Mindy Hsieh, Yingzi Liu, Farshad Mostafaei, Jean M Poulson, Linda H Nie
PURPOSE: Boron neutron capture therapy (BNCT) is a binary treatment modality that uses high LET particles to achieve tumor cell killing. Deuterium-deuterium (DD) compact neutron generators have advantages over nuclear reactors and large accelerators as the BNCT neutron source, such as their compact size, low cost, and relatively easy installation. The purpose of this study is to design a beam shaping assembly (BSA) for a DD neutron generator and assess the potential of a DD-based BNCT system using Monte Carlo (MC) simulations...
February 2017: Medical Physics
https://www.readbyqxmd.com/read/28192346/diagnosis-and-optimization-of-wwtps-using-the-pwm-library-full-scale-experiences
#3
T Fernández-Arévalo, I Lizarralde, M Maiza, S Beltrán, P Grau, E Ayesa
Given the shift in perception of wastewater treatment plants as water resource recovery facilities, conventional mathematical models need to be updated. The resource recovery perspective should be applied to new processes, technologies and plant layouts. The number and level of models proposed to date give an overview of the complexity of the new plant configurations and provides a wide range of possibilities and process combinations in order to construct plant layouts. This diversity makes the development of standard, modular and flexible tools and model libraries that allow the incorporation of new processes and components in a straightforward way a necessity...
February 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28181607/robust-temperature-change-rate-actuated-valving-and-switching-for-highly-integrated-centrifugal-microfluidics
#4
M Keller, G Czilwik, J Schott, I Schwarz, K Dormanns, F von Stetten, R Zengerle, N Paust
We present new unit operations for valving and switching in centrifugal microfluidics that are actuated by a temperature change rate (TCR) and controlled by the rotational frequency. Implementation is realized simply by introducing a comparatively large fluidic resistance to an air vent of a fluidic structure downstream of a siphon channel. During temperature decrease at a given TCR, the air pressure inside the downstream structure decreases and the fluidic resistance of the air vent slows down air pressure compensation allowing a thermally induced underpressure to build up temporarily...
February 9, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28166888/how-much-time-do-drivers-need-to-obtain-situation-awareness-a-laboratory-based-study-of-automated-driving
#5
Zhenji Lu, Xander Coster, Joost de Winter
Drivers of automated cars may occasionally need to take back manual control after a period of inattentiveness. At present, it is unknown how long it takes to build up situation awareness of a traffic situation. In this study, 34 participants were presented with animated video clips of traffic situations on a three-lane road, from an egocentric viewpoint on a monitor equipped with eye tracker. Each participant viewed 24 videos of different durations (1, 3, 7, 9, 12, or 20 s). After each video, participants reproduced the end of the video by placing cars in a top-down view, and indicated the relative speeds of the placed cars with respect to the ego-vehicle...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28166881/modeling-study-of-seated-reach-envelopes-based-on-spherical-harmonics-with-consideration-of-the-difficulty-ratings
#6
Xiaozhi Yu, Jindong Ren, Qian Zhang, Qun Liu, Honghao Liu
Reach envelopes are very useful for the design and layout of controls. In building reach envelopes, one of the key problems is to represent the reach limits accurately and conveniently. Spherical harmonics are proved to be accurate and convenient method for fitting of the reach capability envelopes. However, extensive study are required on what components of spherical harmonics are needed in fitting the envelope surfaces. For applications in the vehicle industry, an inevitable issue is to construct reach limit surfaces with consideration of the seating positions of the drivers, and it is desirable to use population envelopes rather than individual envelopes...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28162916/investigation-on-occupant-injury-severity-in-rear-end-crashes-involving-trucks-as-the-front-vehicle-in-beijing-area-china
#7
Quan Yuan, Meng Lu, Athanasios Theofilatos, Yi-Bing Li
PURPOSE: Rear-end crashes attribute to a large portion of total crashes in China, which lead to many casualties and property damage, especially when involving commercial vehicles. This paper aims to investigate the critical factors for occupant injury severity in the specific rear-end crash type involving trucks as the front vehicle (FV). METHODS: This paper investigated crashes occurred from 2011 to 2013 in Beijing area, China and selected 100 qualified cases i...
November 9, 2016: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28160144/sequence-of-the-ateline-alphaherpesvirus-1-hva1-genome
#8
R Eberle, Darla H Black
Here, we report the genome sequence of a spider monkey alphaherpesvirus (ateline alphaherpesvirus 1, HVA1) and compare it with that of other primate alphaherpesviruses. The HVA1 genome is 147,346 bp long and contains 67 predicted ORFs. The genetic layout of the HVA1 genome is similar to that of the squirrel monkey alphaherpesvirus (saimirine alphaherpesvirus 1, HVS1) in that it lacks inverted repeat regions flanking the unique long region and homologues of the UL43, UL49.5, US8.5 and US10-12 genes. Unlike HVS1, HVA1 also lacks a homologue of the RL1 (γ34...
February 3, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28159113/using-rgb-d-sensors-and-evolutionary-algorithms-for-the-optimization-of-workstation-layouts
#9
Jose Antonio Diego-Mas, Rocio Poveda-Bautista, Diana Garzon-Leal
RGB-D sensors can collect postural data in an automatized way. However, the application of these devices in real work environments requires overcoming problems such as lack of accuracy or body parts' occlusion. This work presents the use of RGB-D sensors and genetic algorithms for the optimization of workstation layouts. RGB-D sensors are used to capture workers' movements when they reach objects on workbenches. Collected data are then used to optimize workstation layout by means of genetic algorithms considering multiple ergonomic criteria...
January 31, 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28155845/design-and-fabrication-of-a-scalable-liver-lobule-on-a-chip-microphysiological-platform
#10
Amin A Banaeiyan, Jannick Theobald, Jurgita Paukštyte, Stefan Wölfl, Caroline B Adiels, Mattias Goksör
The design and fabrication of a very large-scale liver-lobule (VLSLL)-on-a-chip device, providing a microphysiological niche for hepatocytes, is described. The device consists of an integrated network of liver-lobule-like hexagonal tissue-culture chambers constructed in a hybrid layout with a separate seed-feed network. As a key feature, each chamber contains a central outlet mimicking the central vein of a liver lobule. Separating chamber walls located between the culture area and feed network protects cells from the shear force of the convective flow...
February 3, 2017: Biofabrication
https://www.readbyqxmd.com/read/28155320/fragmentation-of-maternal-child-and-hiv-services-a-missed-opportunity-to-provide-comprehensive-care
#11
Lyn J Haskins, Sifiso P Phakathi, Merridy Grant, Ntokozo Mntambo, Aurene Wilford, Christiane M Horwood
BACKGROUND: In South Africa, coverage of services for mothers and babies in the first year of life is suboptimal despite high immunisation coverage over the same time period. Integration of services could improve accessibility of services, uptake of interventions and retention in care. AIM: This study describes provision of services for mothers and babies aged under 1 year. SETTING: Primary healthcare clinics in one rural district in KwaZulu-Natal, South Africa...
December 2, 2016: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/28153705/supporting-patients-with-mental-illness-deconstructing-barriers-to-community-pharmacist-access
#12
Samantha Calogero, Charles F Caley
OBJECTIVES: To discuss the barriers faced by individuals with mental health conditions attempting to access their community pharmacists and to propose solutions toward deconstructing those barriers. SUMMARY: Given the prevalence of mental illness and the frequency at which psychotropic medications are dispensed, community pharmacists have a daily opportunity to engage patients with mental illness and be active participants in community-based mental health care. Yet multiple barriers affect patient access to community pharmacists...
January 30, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28152824/treatment-prices-at-the-point-of-care-pilot
#13
Rebecca W Lau, Leah Tuzzio, Matthew Alan Christianson, Eric Y Chen, Thanh-Hien Phan
: 4 Background: People with cancer increasingly wish to discuss cancer care costs with clinicians. In our organization all price questions go to a central customer service line with limited capacity to address oncology-specific questions. We aimed to improve clinician access to treatment prices to assist them in responding to patient concerns about prices. METHODS: We developed, launched, and evaluated a pilot tool and accompanying workflow for four oncology clinics in an integrated delivery system in WA...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28150959/multiple-views-of-space-continuous-visual-flow-enhances-small-scale-spatial-learning
#14
Corinne A Holmes, Steven A Marchette, Nora S Newcombe
In the real word, we perceive our environment as a series of static and dynamic views, with viewpoint transitions providing a natural link from one static view to the next. The current research examined if experiencing such transitions is fundamental to learning the spatial layout of small-scale displays. In Experiment 1, participants viewed a tabletop array from 4 orientations in 1 of 3 conditions. The control condition presented the array sequentially, as a series of static views. In the remaining conditions, participants experienced the transition between viewpoints by rotating the array or moving around it...
February 2, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28150431/should-learners-reason-one-step-at-a-time-a-randomised-trial-of-two-diagnostic-scheme-designs
#15
Sarah Blissett, Deric Morrison, David McCarty, Matthew Sibbald
CONTEXT: Making a diagnosis can be difficult for learners as they must integrate multiple clinical variables. Diagnostic schemes can help learners with this complex task. A diagnostic scheme is an algorithm that organises possible diagnoses by assigning signs or symptoms (e.g. systolic murmur) to groups of similar diagnoses (e.g. aortic stenosis and aortic sclerosis) and provides distinguishing features to help discriminate between similar diagnoses (e.g. carotid pulse). The current literature does not identify whether scheme layouts should guide learners to reason one step at a time in a terminally branching scheme or weigh multiple variables simultaneously in a hybrid scheme...
February 2, 2017: Medical Education
https://www.readbyqxmd.com/read/28141755/case-management-and-the-documentation-of-avoidable-days
#16
Leah N Shelerud, Jana L Esden
PURPOSE OF STUDY: Avoidable Days/Delays (ADs) account for a large portion of dollars lost for many health care organizations, and with ongoing changes in health care reimbursement, available funds will become increasingly limited. Avoidable Days cannot be reduced or eliminated without accurate causal documentation. The purpose of this study was to determine whether a system upgrade with a change in documentation layout for AD tracking increased case manager compliance with AD documentation...
March 2017: Professional Case Management
https://www.readbyqxmd.com/read/28141522/altering-user-movement-behaviour-in-virtual-environments
#17
Adalberto L Simeone, Ifigeneia Mavridou, Wendy Powell
In immersive Virtual Reality systems, users tend to move in a Virtual Environment as they would in an analogous physical environment. In this work, we investigated how user behaviour is affected when the Virtual Environment differs from the physical space. We created two sets of four environments each, plus a virtual replica of the physical environment as a baseline. The first focused on aesthetic discrepancies, such as a water surface in place of solid ground. The second focused on mixing immaterial objects together with those paired to tangible objects...
January 26, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28139158/usability-and-utility-evaluation-of-the-web-based-should-i-start-insulin-patient-decision-aid-for-patients-with-type-2-diabetes-among-older-people
#18
Yew Kong Lee, Ping Yein Lee, Chirk Jenn Ng, Chin Hai Teo, Ahmad Ihsan Abu Bakar, Khatijah Lim Abdullah, Ee Ming Khoo, Nik Sherina Hanafi, Wah Yun Low, Thiam Kian Chiew
This study aimed to evaluate the usability (ease of use) and utility (impact on user's decision-making process) of a web-based patient decision aid (PDA) among older-age users. A pragmatic, qualitative research design was used. We recruited patients with type 2 diabetes who were at the point of making a decision about starting insulin from a tertiary teaching hospital in Malaysia in 2014. Computer screen recording software was used to record the website browsing session and in-depth interviews were conducted while playing back the website recording...
January 31, 2017: Informatics for Health & Social Care
https://www.readbyqxmd.com/read/28134486/superamphiphobic-bionic-proboscis-for-contamination-free-manipulation-of-nano-and-core-shell-droplets
#19
William S Y Wong, Guanyu Liu, Antonio Tricoli
Manipulation of nanoliter droplets is a key step for many emerging technologies including ultracompact microfluidics devices, 3D and flexible electronic printing. Despite progress, contamination-free generation and release of nanoliter droplets by compact low-cost devices remains elusive. In the present study, inspired by butterflies' minute manipulation of fluids, the authors have engineered a superamphiphobic bionic proboscis (SAP) layout that surpasses synthetic and natural designs. The authors demonstrate the scalable fabrication of SAPs with tunable inner diameters down to 50 µm by the rapid gas-phase nanotexturing of the outer and inner surfaces of readily available hypodermic needles...
January 30, 2017: Small
https://www.readbyqxmd.com/read/28133714/towards-a-building-typology-and-terminology-for-irish-hospitals
#20
REVIEW
T Grey, S Kennelly, P de Freine, S Mahon, V Mannion, D O'Neill
BACKGROUND: The physical form of the hospital environment shapes the care setting and influences the relationship of the hospital to the community. Due to ongoing demographic change, evolving public health needs, and advancing medical practice, typical hospitals are frequently redeveloped, retrofitted, or expanded. It is argued that multi-disciplinary and multi-stakeholder approaches are required to ensure that hospital design matches these increasingly complex needs. To facilitate such a conversation across different disciplines, experts, and community stakeholders, it is helpful to establish a hospital typology and associated terminology as part of any collaborative process...
January 30, 2017: Irish Journal of Medical Science
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