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https://www.readbyqxmd.com/read/29145584/critical-lessons-from-high-value-oncology-practices
#1
Douglas W Blayney, Melora K Simon, Beatrice Podtschaske, Scott Ramsey, Margaret Shyu, Craig Lindquist, Arnold Milstein
Importance: Cancer care is expensive. Cancer care provided by practice organizations varies in total spending incurred by patients and payers during treatment episodes and in quality of care, and this unnecessary variation contributes to the high cost. Objective: To use the variation in total spending and quality of care to assess oncology practice attributes distinguishing "high value" that may be tested and adopted by others to produce similar results. Design, Setting, and Participants: "Positive deviance" was used in this exploratory mixed-methods (quantitative and qualitative) analysis of interview results...
November 16, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29141608/traveler-a-tool-for-template-based-rna-secondary-structure-visualization
#2
Richard Elias, David Hoksza
BACKGROUND: Visualization of RNA secondary structures is a complex task, and, especially in the case of large RNA structures where the expected layout is largely habitual, the existing visualization tools often fail to produce suitable visualizations. This led us to the idea to use existing layouts as templates for the visualization of new RNAs similarly to how templates are used in homology-based structure prediction. RESULTS: This article introduces Traveler, a software tool enabling visualization of a target RNA secondary structure using an existing layout of a sufficiently similar RNA structure as a template...
November 15, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29130752/self-reported-difficulty-and-preferences-of-wheeled-mobility-device-users-for-simulated-low-floor-bus-boarding-interior-circulation-and-disembarking
#3
Clive D'Souza, Victor L Paquet, James A Lenker, Edward Steinfeld
BACKGROUND: Low ridership of public transit buses among wheeled mobility device users suggests the need to identify vehicle design conditions that are either particularly accommodating or challenging. The objective of this study was to determine the effects of low-floor bus interior seating configuration and passenger load on wheeled mobility device user-reported difficulty, overall acceptability and design preference. METHODS: Forty-eight wheeled mobility users evaluated three interior design layouts at two levels of passenger load (high vs...
November 13, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29130275/feng-shui-and-emotional-response-in-the-critical-care-environment-farce-study
#4
R Charles, S Glover, K Bauchmüller, D Wood
The aim of this study was to investigate the relationship between nursing staff emotions and their surrounding environment, using the ancient system of feng shui. Two orientations of critical care bed spaces (wind and water groups, respectively) were mapped using a western bagua. Energy or 'chi' scores for nine emotions were calculated based on the positive or negative flow of chi in each of the two groups. During a two-week period, nursing staff were allocated to work in a bed space in either the wind or water groups; nursing staff who were not allocated to a study bed space acted as a control group...
December 2017: Anaesthesia
https://www.readbyqxmd.com/read/29128990/erratum-to-fertility-sparing-for-young-patients-with-gynecologic-cancer-how-mri-can-guide-patient-selection-prior-to-conservative-management
#5
Sinead H McEvoy, Stephanie Nougaret, Nadeem R Abu-Rustum, Hebert Alberto Vargas, Elizabeth A Sadowski, Christine O Menias, Fuki Shitano, Shinya Fujii, Ramon E Sosa, Joanna G Escalon, Evis Sala, Yulia Lakhman
The original version of this article unfortunately contained mistakes. The figures 7D, 7E and 7F were missing in the article and arrows were missing in the figures 6C, 8B and 11C. The year of publication and volume number for references 19, 79 and 87 have been updated. Also, the Table 2 layout has been improved for better readability. The Publisher apologizes for the mistakes and the inconvenience caused.
November 11, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29128763/improving-the-hydrocarbon-production-via-co-pyrolysis-of-bagasse-with-bio-plastic-and-dual-catalysts-layout
#6
Huiyan Zhang, Peter Keliona Wani Likun, Rui Xiao
Catalytic fast pyrolysis (CFP) of bagasse and bio-plastic (chicken feather keratin) and their mixtures were conducted to produce aromatic hydrocarbons over a HZSM-5, USY, and dual-catalysts layout. The effects of temperature, co-feeding ratios, feed-to-catalyst ratios and dual catalysts on hydrocarbon yields and selectivities were investigated. The results show a general improvement in the aromatic hydrocarbons yields in all cases compared to non-catalytic and pure biomass pyrolysis. The aromatic hydrocarbons increased by 10 fold with the increase of temperature from 400°C to 700°C...
November 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29123674/characterization-of-temporal-coherence-of-hard-x-ray-free-electron-laser-pulses-with-single-shot-interferograms
#7
Taito Osaka, Takashi Hirano, Yuki Morioka, Yasuhisa Sano, Yuichi Inubushi, Tadashi Togashi, Ichiro Inoue, Kensuke Tono, Aymeric Robert, Kazuto Yamauchi, Jerome B Hastings, Makina Yabashi
Temporal coherence is one of the most fundamental characteristics of light, connecting to spectral information through the Fourier transform relationship between time and frequency. Interferometers with a variable path-length difference (PLD) between the two branches have widely been employed to characterize temporal coherence properties for broad spectral regimes. Hard X-ray interferometers reported previously, however, have strict limitations in their operational photon energies, due to the specific optical layouts utilized to satisfy the stringent requirement for extreme stability of the PLD at sub-ångström scales...
November 1, 2017: IUCrJ
https://www.readbyqxmd.com/read/29123136/benchmarking-integrated-linear-optical-architectures-for-quantum-information-processing
#8
Fulvio Flamini, Nicolò Spagnolo, Niko Viggianiello, Andrea Crespi, Roberto Osellame, Fabio Sciarrino
Photonic platforms represent a promising technology for the realization of several quantum communication protocols and for experiments of quantum simulation. Moreover, large-scale integrated interferometers have recently gained a relevant role in quantum computing, specifically with Boson Sampling devices and the race for quantum supremacy. Indeed, various linear optical schemes have been proposed for the implementation of unitary transformations, each one suitable for a specific task. Notwithstanding, so far a comprehensive analysis of the state of the art under broader and realistic conditions is still lacking...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29122584/how-to-build-an-allogeneic-hematopoietic-cell-transplant-unit-in-2016-proposal-for-a-practical-framework
#9
M Crysandt, I Yakoub-Agha, P Reiß, S Theisen, G Silling, P Glatte, E Nelles, S Lemmen, T H Brümmendorf, U Kontny, E Jost
Allogeneic hematopoietic cell transplantation is part of the standard of care for many hematological diseases. Over the last decades, significant advances in patient and donor selection, conditioning regimens as well as supportive care of patients undergoing allogeneic hematopoietic cell transplantation leading to improved overall survival have been made. In view of many new treatment options in cellular and molecular targeted therapies, the place of allogeneic transplantation in therapy concepts must be reviewed...
November 6, 2017: Current Research in Translational Medicine
https://www.readbyqxmd.com/read/29122194/multi-directional-one-handed-strength-assessments-using-anybody-modeling-systems
#10
Divyaksh Subhash Chander, Maria Pia Cavatorta
Digital human modeling tools support proactive ergonomics in optimizing work tasks and workplace layouts. Empirical-statistical model based tools are often used to estimate the force exertion capability of the operators. This work is intended to serve as an initial probing into the usability of a musculoskeletal model based software, AnyBody Modeling Systems (AMS), in evaluating the force exertion capability at different points in the workspace and for various exertion directions. As a first step, it focuses on the modeling approach and the accuracy of one-handed isometric strength estimates of AMS...
February 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29119176/a-novel-microfluidic-microelectrode-chip-for-a-significantly-enhanced-monitoring-of-npy-receptor-activation-in-live-mode
#11
Franziska D Zitzmann, Heinz-Georg Jahnke, Felix Nitschke, Annette G Beck-Sickinger, Bernd Abel, Detlev Belder, Andrea A Robitzki
Lab-on-a-chip devices that combine, e.g. chemical synthesis with integrated on-chip analytics and multi-compartment organ-on-a-chip approaches, are a fast and attractive evolving research area. While integration of appropriate cell models in microfluidic setups for monitoring the biological activity of synthesis products or test compounds is already in focus, the integration of label-free bioelectronic analysis techniques is still poorly realized. In this context, we investigated the capabilities of impedance spectroscopy as a non-destructive real-time monitoring technique for adherent cell models in a microfluidic setup...
November 9, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/29118683/the-e-health-literacy-demands-of-australia-s-my-health-record-a-heuristic-evaluation-of-usability
#12
Louisa Walsh, Bronwyn Hemsley, Meredith Allan, Natalie Adams, Susan Balandin, Andrew Georgiou, Isabel Higgins, Shaun McCarthy, Sophie Hill
Background: My Health Record is Australia's electronic personal health record system, which was introduced in July 2012. As of August 2017, approximately 21 percent of Australia's total population was registered to use My Health Record. Internationally, usability issues have been shown to negatively influence the uptake and use of electronic health record systems, and this scenario may particularly affect people who have low e-health literacy. It is likely that usability issues are negatively affecting the uptake and use of My Health Record in Australia...
2017: Perspectives in Health Information Management
https://www.readbyqxmd.com/read/29117927/sexual-health-and-the-internet-cross-sectional-study-of-online-preferences-among-adolescents
#13
Antonella Juline von Rosen, Frederik Tilmann von Rosen, Peter Tinnemann, Falk Müller-Riemenschneider
BACKGROUND: The Internet is widely used by adolescents for sexual health information and bears the potential to increase knowledge and positively affect behavior. OBJECTIVE: The objective of this study is to assess students' preferences when looking for sexual health information online. METHODS: We conducted a cross-sectional survey among ninth grade students in a convenience sample of 13 secondary schools in Berlin, Germany. During a regular school period, participants were requested to rate the importance they attribute to nine aspects of sexual health websites in a paper-based questionnaire...
November 8, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29116442/introduction
#14
Ricardo Gattass, Juliana G M Soares, Bruss Lima
The pulvinar can be subdivided into well-delimitated regions based on chemoarchitectural, cytoarchitectural, myeloarchitectural, connectivity, and electrophysiological criteria. Subdivisions of the pulvinar based on its chemoarchitectural features are the most consistently preserved across species of New and Old World monkeys. It is reasonable to speculate that the occurrence and distribution of calcium-binding proteins in the pulvinar, such as calbindin and parvalbumin, have been preserved along evolution...
2018: Advances in Anatomy, Embryology, and Cell Biology
https://www.readbyqxmd.com/read/29114246/variation-of-carbohydrate-active-enzyme-patterns-in-the-gut-microbiota-of-italian-healthy-subjects-and-type-2-diabetes-patients
#15
Matteo Soverini, Silvia Turroni, Elena Biagi, Sara Quercia, Patrizia Brigidi, Marco Candela, Simone Rampelli
The human gut microbiota (GM) has been associated, to date, with various complex functions, essentials for the host health. Among these, it is certainly worth noting the degradation of the so-called microbiota-accessible carbohydrates (MACs), which the GM breaks down through specific enzymes, referred to as carbohydrate-active enzymes (CAZymes). This degradation constitutes the first step in the production of short-chain fatty acids (SCFAs), key microbial small molecules having multiple health-promoting effects for the host organism...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29109426/fault-tolerant-interface-between-quantum-memories-and-quantum-processors
#16
Hendrik Poulsen Nautrup, Nicolai Friis, Hans J Briegel
Topological error correction codes are promising candidates to protect quantum computations from the deteriorating effects of noise. While some codes provide high noise thresholds suitable for robust quantum memories, others allow straightforward gate implementation needed for data processing. To exploit the particular advantages of different topological codes for fault-tolerant quantum computation, it is necessary to be able to switch between them. Here we propose a practical solution, subsystem lattice surgery, which requires only two-body nearest-neighbor interactions in a fixed layout in addition to the indispensable error correction...
November 6, 2017: Nature Communications
https://www.readbyqxmd.com/read/29108485/minimising-the-risk-of-mycobacterium-chimaera-infection-during-cardiopulmonary-bypass-by-the-removal-of-heater-cooler-units-from-the-operating-room
#17
Thomas A Barker, Uday Dandekar, Nina Fraser, Lincoln Dawkin, Paul Sweeney, Fraser Heron, Jacqui Simmons, Jitendra Parmar
INTRODUCTION: Mycobacterium chimaera ( M. chimaera) is a recently characterised bacterium that can cause life-threatening infections in small numbers of patients who undergo cardiopulmonary bypass during cardiac surgery. The likely mode of transmission is thought to occur through aerosolisation from contaminated water reservoirs. The airborne bacteria then contaminate the surgical field, leading to an infection months or even years later. The preferred practical solution to disrupt the transmission of these airborne bacteria to the patient is to remove the heater-cooler units (HCUs) from the operating room (OR)...
November 1, 2017: Perfusion
https://www.readbyqxmd.com/read/29107587/women-s-perceptions-of-usefulness-and-ease-of-use-of-four-healthy-eating-blog-characteristics-a-qualitative-study-of-33-french-canadian-women
#18
Véronique Bissonnette-Maheux, Audrée-Anne Dumas, Véronique Provencher, Annie Lapointe, Marilyn Dugrenier, Sharon Straus, Marie-Pierre Gagnon, Sophie Desroches
BACKGROUND: Healthy eating blogs are knowledge translation tools used by nutrition and dietetics practitioners for helping people improve their health behaviors and food choices. OBJECTIVE: Our aim was to explore women's perceptions of the usefulness and ease of use of healthy eating blog (HEB) characteristics that might increase potential users' intention to use them as tools to improve their dietary habits. DESIGN: We conducted qualitative research using semi-structured individual interviews...
October 26, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29107546/life-long-neurogenic-activity-of-individual-neural-stem-cells-and-continuous-growth-establish-an-outside-in-architecture-in-the-teleost-pallium
#19
Giacomo Furlan, Valentina Cuccioli, Nelly Vuillemin, Lara Dirian, Anna Janue Muntasell, Marion Coolen, Nicolas Dray, Sébastien Bedu, Corinne Houart, Emmanuel Beaurepaire, Isabelle Foucher, Laure Bally-Cuif
Spatiotemporal variations of neurogenesis are thought to account for the evolution of brain shape. In the dorsal telencephalon (pallium) of vertebrates, it remains unresolved which ancestral neurogenesis mode prefigures the highly divergent cytoarchitectures that are seen in extant species. To gain insight into this question, we developed genetic tools to generate here the first 4-dimensional (3D + birthdating time) map of pallium construction in the adult teleost zebrafish. Using a Tet-On-based genetic birthdating strategy, we identify a "sequential stacking" construction mode where neurons derived from the zebrafish pallial germinal zone arrange in outside-in, age-related layers from a central core generated during embryogenesis...
November 6, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29104229/high-accuracy-readout-electronics-for-piezoresistive-tactile-sensors
#20
José A Hidalgo-López, Óscar Oballe-Peinado, Julián Castellanos-Ramos, José A Sánchez-Durán, Raquel Fernández-Ramos, Fernando Vidal-Verdú
The typical layout in a piezoresistive tactile sensor arranges individual sensors to form an array with M rows and N columns. While this layout reduces the wiring involved, it does not allow the values of the sensor resistors to be measured individually due to the appearance of crosstalk caused by the nonidealities of the array reading circuits. In this paper, two reading methods that minimize errors resulting from this phenomenon are assessed by designing an electronic system for array reading, and the results are compared to those obtained using the traditional method, obviating the nonidealities of the reading circuit...
November 1, 2017: Sensors
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