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https://www.readbyqxmd.com/read/28433394/a-modelling-comparison-between-received-sound-levels-produced-by-a-marine-vibroseis-array-and-those-from-an-airgun-array-for-some-typical-seismic-survey-scenarios
#1
Alec J Duncan, Linda S Weilgart, Russell Leaper, Michael Jasny, Sharon Livermore
Marine Vibroseis (MV) may provide a marine seismic sound source that has less environmental impact than conventional airguns. Modelled sound levels from a realistic MV array and airgun array with similar downward energy at frequencies <100Hz were compared under three scenarios: shallow, deep, and slope. Changing the layout of the MV array's higher frequency sources reduced sound exposure levels (SELs) by 4dB. At 100m range this MV was 20dB lower in peak-to-peak sound pressure level vs. the airgun array, decreasing to 12dB lower at 5km, the maximum modelled range for peak levels...
April 19, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28432013/design-of-multielectrode-arrays-for-uniform-sampling-of-different-orientations-of-tuned-unit-populations-in-the-cat-visual-cortex
#2
Yoshiko Maruyama, Hiroyuki Ito
For better reconstruction of stimulus orientation from a single trial activity of the neuron population in the visual cortex, we need uniform samplings of differently oriented tuned neurons. We recorded multiple neurons simultaneously by using either a four-tetrode array or an eight-microelectrode array, and examined what kinds of electrodes and layouts provided a more homogeneous distribution of the units' optimal orientations. The unit population sampled by a four-tetrode array showed more homogeneous distribution than those sampled by an eight-microelectrode array...
April 18, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/28426159/open-microfluidic-gel-electrophoresis-rapid-and-low-cost-separation-and-analysis-of-dna-at-the-nanoliter-scale
#3
Ludwig Gutzweiler, Tobias Gleichmann, Laurent Tanguy, Peter Koltay, Roland Zengerle, Lutz Riegger
Gel electrophoresis is one of the most applied and standardized tools for separation and analysis of macromolecules and their fragments in academic research and in industry. In this work we present a novel approach for conducting on-demand electrophoretic separations of DNA molecules in open microfluidic (OM) systems on planar polymer substrates. The approach combines advantages of slab gel, capillary- & chip-based methods offering low consumable costs (<0.1 $) circumventing cost intensive microfluidic chip fabrication, short process times (5 minutes per analysis) and high sensitivity (4 ng/μl dsDNA) combined with reasonable resolution (17 bases)...
April 20, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28426080/c-reactive-protein-and-interleukin-6-microfluidic-immunoassays-with-on-chip-pre-stored-reagents-and-centrifugo-pneumatic-liquid-control
#4
Y Zhao, G Czilwik, V Klein, K Mitsakakis, R Zengerle, N Paust
We present a fully automated centrifugal microfluidic method for particle based protein immunoassays. Stick-pack technology is employed for pre-storage and release of liquid reagents. Quantitative layout of centrifugo-pneumatic particle handling, including timed valving, switching and pumping is assisted by network simulations. The automation is exclusively controlled by the spinning frequency and does not require any additional means. New centrifugal microfluidic process chains are developed in order to sequentially supply wash buffer based on frequency dependent stick-pack opening and pneumatic pumping to perform two washing steps from one stored wash buffer; pre-store and re-suspend functionalized microparticles on a disk; and switch between the path of the waste fluid and the path of the substrate reaction product with 100% efficiency...
April 20, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28423853/square
#5
Carsten Oliver Schmidt, Christine Krabbe, Janka Schössow, Martin Albers, Dörte Radke, Jörg Henke
Valid scientific inferences from epidemiological and clinical studies require high data quality. Data generating departments therefore aim to detect data irregularities as early as possible in order to guide quality management processes. In addition, after the completion of data collections the obtained data quality must be evaluated. This can be challenging in complex studies due to a wide scope of examinations, numerous study variables, multiple examiners, devices, and examination centers. This paper describes a Java EE web application used to monitor and evaluate data quality in institutions with complex and multiple studies, named Square<sup>2</sup>...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28414312/high-resolution-myogenic-lineage-mapping-by-single-cell-mass-cytometry
#6
Ermelinda Porpiglia, Nikolay Samusik, Andrew Tri Van Ho, Benjamin D Cosgrove, Thach Mai, Kara L Davis, Astraea Jager, Garry P Nolan, Sean C Bendall, Wendy J Fantl, Helen M Blau
Muscle regeneration is a dynamic process during which cell state and identity change over time. A major roadblock has been a lack of tools to resolve a myogenic progression in vivo. Here we capitalize on a transformative technology, single-cell mass cytometry (CyTOF), to identify in vivo skeletal muscle stem cell and previously unrecognized progenitor populations that precede differentiation. We discovered two cell surface markers, CD9 and CD104, whose combined expression enabled in vivo identification and prospective isolation of stem and progenitor cells...
April 17, 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/28413982/optimizing-adas-cog-worksheets-a-survey-of-clinical-trial-raters-perceptions
#7
Stephen M Meyer, Kristina A Bertzos, Magdalena Perez, Donald Connor, Kimberly Schafer, Sarah Walter
The Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) remains the most widely used test of longitudinal cognitive functioning in Alzheimer's disease (AD) clinical trials. Unlike most neuropsychological tests, the ADAS-Cog source documentation worksheets are not uniform across clinical trials, and vary by document layout, inclusion of administration and/or scoring instructions, and documentation of subtest scoring (e.g., recording correct versus incorrect scores), among other differences. Many ADAS-Cog test administrators (raters) participate in multiple AD trials and switching between different ADAS-Cog worksheets may increase the likelihood of administration and/or scoring mistakes that lessen the reliability of the instrument...
April 17, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28412622/population-production-pollution-nexus-based-air-pollution-management-model-for-alleviating-the-atmospheric-crisis-in-beijing-china
#8
X T Zeng, Y F Tong, L Cui, X M Kong, Y N Sheng, L Chen, Y P Li
In recent years, increscent emissions in the city of Beijing due to expanded population, accelerated industrialization and inter-regional pollutant transportation have led to hazardous atmospheric pollution issues. Although a number of anthropogenic control measures have been put into use, frequent/severe haze events have still challenged regional governments. In this study, a hybrid population-production-pollution nexus model (PPP) is proposed for air pollution management and air quality planning (AMP) with the aim to coordinate human activities and environmental protection...
April 13, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28412498/impact-of-thalamocortical-input-on-barrel-cortex-development
#9
Francisco J Martini, Verónica Moreno-Juan, Anton Filipchuk, Miguel Valdeolmillos, Guillermina López-Bendito
The development of cortical maps requires the balanced interaction between genetically determined programs and input/activity-dependent signals generated spontaneously or triggered from the environment. The somatosensory pathway of mice provides an excellent scenario to study cortical map development because of its highly organized cytoarchitecture, known as the barrel field. This precise organization makes evident even small alterations in the cortical map layout. In this review, we will specially focus on the thalamic factors that control barrel field development...
April 12, 2017: Neuroscience
https://www.readbyqxmd.com/read/28411744/effects-of-transit-bus-interior-configuration-on-performance-of-wheeled-mobility-users-during-simulated-boarding-and-disembarking
#10
Clive D'Souza, Victor Paquet, James A Lenker, Edward Steinfeld
The emergence of low-floor bus designs and related regulatory standards in the U.S. have resulted in substantial improvements in public transit accessibility. However, passengers using wheeled mobility devices still experience safety concerns and inefficiencies in boarding, disembarking, and interior circulation on low-floor buses. This study investigates effects of low-floor bus interior configuration and passenger crowding on boarding and disembarking efficiency and safety. Users of manual wheelchairs (n = 18), powered wheelchairs (n = 21) and electric scooters (n = 9) simulated boarding and disembarking in three interior layout configurations at low and high passenger crowding conditions on a full-scale laboratory mock-up of a low-floor bus...
July 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28406884/use-of-video-directly-observed-therapy-for-treatment-of-latent-tuberculosis-infection-johnson-county-kansas-2015
#11
Elizabeth Lawlor Holzschuh, Stacie Province, Krystle Johnson, Caitlin Walls, Cathy Shemwell, Gary Martin, Amy Showalter, Jennifer Dunlay, Andrew Conyers, Phil Griffin, Nancy Tausz
Tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis and is spread from person to person through the air. TB can be spread in congregate settings, such as school environments, to varying degrees, based on factors including duration of contact and air ventilation (1); therefore, evaluating potential contacts and exposures can be challenging. In February 2015, a student at a Kansas high school received a diagnosis of active pulmonary TB disease. Screening of 385 (91%) school contacts, four (100%) household contacts, and 19 (90%) social contacts resulted in the identification of 50 persons with latent TB infection...
April 14, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28402393/metcirc-navigating-mass-spectral-similarity-in-high-resolution-ms-ms-metabolomics-data
#12
Thomas Naake, Emmanuel Gaquerel
Summary: Among the main challenges in metabolomics are the rapid dereplication of previously characterized metabolites across a range of biological samples and the structural prediction of unknowns from MS/MS data. Here, we developed MetCirc to comprehensively align and calculate pairwise similarity scores among MS/MS spectral data and visualize these across a range of biological samples. MetCirc comprises functionalities to interactively organize these data according to compound familial groupings and to accelerate the discovery of shared metabolites and hypothesis formulation for unknowns...
April 11, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28400180/reducing-barriers-to-patient-reported-outcome-measures-for-people-with-cognitive-impairments
#13
Jessica M Kramer, Ariel Schwartz
The field of rehabilitation has increasingly called for the use of patient reported outcome measures (PROMs) in research and practice. Given that many rehabilitation clients present with conditions associated with cognitive impairments, it is imperative to reduce barriers to PROM use for this population. The purpose of this paper is develop a comprehensive understanding of cognitive accessibility that can prospectively inform the design of PROMs. We put forth the following definition of cognitive accessibility for PROMs: Cognitive accessibility is present when assessment design anticipates respondent variability in cognitive abilities and, to the greatest extent possible, reduces cognitive demands and/or supports cognitive processes to enable respondents with a range of cognitive abilities to interpret and respond to assessment items as intended...
April 8, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28391213/integration-of-low-power-asic-and-mems-sensors-for-monitoring-gastrointestinal-tract-using-a-wireless-capsule-system
#14
Md Shamsul Arefin, Jean-Michel Redoute, Mehmet Yuce
This paper presents a wireless capsule microsystem to detect and monitor pH, pressure, and temperature of the gastrointestinal (GI) tract in real-time. This research contributes to the integration of sensors (microfabricated capacitive pH, capacitive pressure, and resistive temperature sensors), frequency modulation and pulse-width modulation based interface IC circuits, microcontroller, and transceiver with meandered conformal antenna for the development of a capsule system. The challenges associated with the system miniaturization, higher sensitivity and resolution of sensors, and lower power consumption of interface circuits are addressed...
April 4, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28382845/factors-promoting-sense-of-coherence-among-university-students-in-urban-areas-of-japan-individual-level-social-capital-self-efficacy-and-mental-health
#15
Mie Mato, Keiko Tsukasaki
OBJECTIVE: Sense of coherence (SOC) is a concept that helps to explain the relation between personal intentionality as psychosocial factors and health-related behaviors. Thus, it is essential to enhance SOC when encouraging a healthy lifestyle. However, the factors that promote SOC have not been fully investigated among university students. The objective of this study was to clarify the general resistance resources (GRRs) that may promote the development of the SOC among university students...
April 1, 2017: Global Health Promotion
https://www.readbyqxmd.com/read/28381053/lithographic-source-optimization-based-on-adaptive-projection-compressive-sensing
#16
Xu Ma, Dongxiang Shi, Zhiqiang Wang, Yanqiu Li, Gonzalo R Arce
This paper proposes to use the a-priori knowledge of the target layout patterns to design data-adaptive compressive sensing (CS) methods for efficient source optimization (SO) in lithography systems. A set of monitoring pixels are selected from the target layout based on blue noise random patterns. The SO is then formulated as an under-determined linear problem to improve image fidelity according to the monitoring pixels. Adaptive projections are then designed, based on the a-priori knowledge of the target layout, in order to further reduce the dimension of the optimization problem, while trying to retain the SO performance...
March 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28380919/research-on-a-bimorph-piezoelectric-deformable-mirror-for-adaptive-optics-in-optical-telescope
#17
Hairen Wang
We have proposed a discrete-layout bimorph piezoelectric deformable mirror (DBPDM) and developed its realistic electromechanical model. Compared with the conventional piezoelectric deformable mirror (CPDM) and the bimorph piezoelectric deformable mirror (BPDM), the DBPDM has both a larger stroke and a higher resonance frequency by integrating the strengths of the CPDM and the BPDM. To verify the advancement, a 21-elements DBPDM is studied in this paper. The results have suggested that the stroke of the DBPDM is larger than 10 microns and its resonance frequency is 53...
April 3, 2017: Optics Express
https://www.readbyqxmd.com/read/28380826/optimal-design-of-4lp-mode-multicore-fibers-for-high-spatial-multiplicity
#18
Yuki Tobita, Takeshi Fujisawa, Taiji Sakamoto, Takashi Matsui, Shota Saitoh, Katsuhiro Takenaga, Kazuhiko Aikawa, Shinichi Aozasa, Kazuhide Nakajima, Kunimasa Saitoh
High spatial multiplicity fiber designs are presented for homogeneous and heterogeneous 4LP-mode multicore fibers (MCFs) that support six spatial modes per core. The high-spatial-density 4LP-mode MCF design methodology is explained in detail. The influence of the number of cores on the cladding diameter (D<sub>cl</sub>) and relative core multiplicity factor (RCMF) is investigated. The optimal core designs and MCF layouts with square and triangular lattices maintain glass fiber reliability (maximum D<sub>cl</sub> = 250 μm)...
March 6, 2017: Optics Express
https://www.readbyqxmd.com/read/28378912/a-comparison-between-tracer-gas-and-aerosol-particles-distribution-indoors-the-impact-of-ventilation-rate-interaction-of-airflows-and-presence-of-objects
#19
Mariya Bivolarova, Jakub Ondráček, Arsen Melikov, Vladimir Zdimal
The study investigated the separate and combined effects of ventilation rate, free convection flow produced by a thermal manikin, and the presence of objects on the distribution of tracer gas and particles in indoor air. The concentration of aerosol particles and tracer gas was measured in a test room with mixing ventilation. Three layouts were arranged: an empty room, an office room with an occupant sitting in front of a table, and a single-bed hospital room. The room occupant was simulated by a thermal manikin...
April 5, 2017: Indoor Air
https://www.readbyqxmd.com/read/28378675/student-life-student-to-newly-qualified-nurse-make-a-checklist
#20
Jessica Ross
It is natural to feel nervous and apprehensive on your first day in uniform, but hopefully you will also feel excited. Your first day is a celebration of all the hard-won achievements throughout your training, so here are a few tips to help you make the most of it: » Organise a ward induction beforehand, or have a look around. Knowing where you are going and what your workplace looks like can help quell your nerves. » Running around trying to find a pair of scrubs to wear during handover is not ideal, so see if you can get your uniform in advance...
April 5, 2017: Nursing Standard
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