Thayane Rafaela Feola Pizzo, Ana Paula Valverde, Lucas Eduardo Orzari, Luiz Gustavo Terciotti, Robson Damasceno de Lima, Fernando Russo Costa do Bomfim, Marcelo Augusto Marreto Esquisatto, Thiago Antônio Moretti de Andrade, Maria Esméria Corezola do Amaral, Camila Andrea de Oliveira, Maíra Felonato
Renovascular hypertension (RHV) is the cause of high blood pressure due to left renal ischemia, and obesity and hypertension cause an inflammatory response. This work analyzed the inflammatory and tissue repair profile in renal, hepatic, and cardiac tissues in an animal model of RVH associated with a high-fat diet and caloric restriction. The expressions of RORγ-t, IL-17, T-bet, and TNF-α decreased and IFN-γ increased in the right kidney. In relation to the left kidney, caloric restriction decreased the expression of IFN-γ...
September 25, 2023: Canadian Journal of Physiology and Pharmacology