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Asher Zafrany, Jennifer Ben-Oz, Gilad Segev, Joshua Milgram, Orly Zemer, Henrik Elvang Jensen, Efrat Kelmer
This case report describes the successful treatment of a Persian cat diagnosed with intra-abdominal fungal pseudomycetoma causing hypercalcaemia and constipation due to an extra-luminal mechanical obstruction of the colon. Treatment included surgical excision, supportive care and itraconazole for 6 months.
April 2014: Journal of Feline Medicine and Surgery
Mariantonieta Tirado-González, Elizabeth Ball, Angela Ruiz, Ysabel Rodriguez, Carmen Elena Goudet, Oksana Finkel, Haim Golan, Helena Martinez de Morentin, Hanna Sprecher, Eli Sprecher, Andrea Gat
BACKGROUND: Dermatophyte infection is almost exclusively a superficial cutaneous mycosis usually confined to the stratum corneum of nails and hairs of normal hosts. Deep cutaneous and subcutaneous infections due to dermatophytes are exceedingly rare and usually limited to immunosuppressed individuals. These infections remain chronic and persist in spite of treatment. MATERIALS AND METHODS: We report two clinical cases of disseminated dermatophytic pseudomycetoma caused by Microsporum gypseum and Microsporum canis in immunosuppressed patients...
December 2012: International Journal of Dermatology
So-Young Lee, Jong-Hyun Yoo, Hee-Myung Park, Dae Young Kim
No abstract text is available yet for this article.
September 1, 2011: Journal of the American Veterinary Medical Association
Shih-Chieh Chang, Jiunn-Wang Liao, Ching-Lin Shyu, Wei-Li Hsu, Min-Liang Wong
The aim of this retrospective study was to describe the clinical characteristics and treatment of four cats with dermatophytic pseudomycetoma. Four Persian cats, one female and three males, with age ranging from 1.4 to 5 years, were diagnosed with dermatophytic pseudomycetoma by histological examination and fungal culture. Wood's lamp examination revealed positive fluorescence of hairs in all four cats. Characteristic skin lesions consisted of multifocal, raised, firm and nodular to dome-shaped lesions varying in size from 1 to 8 cm in diameter, with ulcers or fistulas in some of the lesions...
April 2011: Veterinary Dermatology
Márcia de Oliveira Nobre, Eduardo Negri Mueller, Mariana Teixeira Tillmann, Cristiano da Silva Rosa, Thomas Normanton Guim, Patrícia Vives, Matheus Fernandes, Isabel Martins Madrid, Cristina Gevehr Fernandes, Mario Carlos Araújo Meireles
BACKGROUND: Dermatophytic pseudomycetoma is a subcutaneous fungal infection by Microsporum canis. AIMS: This work describes a case of dermatophytic pseudomycetoma in a Persian cat. PATIENT AND METHODS: A 3-year old female Persian cat showing alopecia, scaling and ulcerated nodules throughout the body, with presence of ulcerated nodules with yellow granular discharges on the dorsum, close to the tail. Mycological and histopathological examinations were realized...
June 30, 2010: Revista Iberoamericana de Micología
David Eshar, Jörg Mayer, John H Keating
No abstract text is available yet for this article.
March 2010: Lab Animal
Richard I Miller
IDEXX Laboratories database of cases submitted from the UK between March 2005 and February 2008 (36 months) was investigated for feline nodular granulomatous skin disease associated with fungal infection. Cytological and/or histological slides were reviewed and the diagnosis was based on the microscopic pattern of the inflammatory response and morphology of the causative organism. Aetiological diagnoses were hyalohyphomycosis (64 of 77 cases), phaeohyphomycosis (five of 77 cases) and dermatophytic pseudomycetoma (eight of 77 cases)...
April 2010: Veterinary Dermatology
A Thian, A J Woodgyer, S A Holloway
A 4-year-old Domestic Long-hair cat was presented with two large non-painful, ulcerated and suppurative lesions over the flanks. Histopathology and cytology were consistent with fungal pyogranulomatous inflammation. Culture of tissue yielded a dysgonic strain of Microsporum canis. The cat was treated successfully by staged en bloc resections of the lesions, followed by oral ketoconazole, then oral terbinafine. This is the first reported case of dermatophytic pseudomycetoma in a Domestic Long-hair cat in Australia...
August 2008: Australian Veterinary Journal
Skye W Stanley, Anthony J Fischetti, Henrik E Jensen
A 6-year-old Persian cat was examined for constipation, anorexia, and vomiting that was subsequently found to be due to a pseudomycetoma originating from the descending colon and sublumbar region, and causing mechanical obstruction of the colon and rectum. Multiple discrete hyperechoic foci likely representing fungal grains within the lesion gave the mass a coarse echotexture on ultrasound and was supportive of the diagnosis and computed tomography allowed delineation the extent of the mass. A pseudomycetoma is a granulomatous/pyogranulomatous reaction that surrounds dermatophytic fungal hyphae...
March 2008: Veterinary Radiology & Ultrasound
Oralia Barboza-Quintana, Raquel Garza-Guajardo, Carlos Assad-Morel, Nora Méndez-Olvera
BACKGROUND: Fine needle aspiration biopsy (FNAB) of the skin is useful in subcutaneous lesions. Dermatophytes are almost exclusively superficial cutaneous mycoses and constitute 70-80% of all mycoses and 5% of dermatologic consultations. Inflammatory and invasive forms, as well as infections that remain in chronic forms or persist in spite of treatment, are more frequent in immunocompromised individuals. The clinicalpresentations of these invasive cases are dermatopbytic granulomas (granuloma of Wilson-Majocchi and pseudomycetoma) or Hadida's disease...
May 2007: Acta Cytologica
Simona Nardoni, Alberto Franceschi, Francesca Mancianti
The effectiveness of a simple PCR protocol performed on paraffin-embedded tissues, obtained from histopathologically and culturally diagnosed cases of dermatophytic pseudomycetoma DPM was tested. The specimens were investigated using previously described primers (DH1L and DH1R) targeting the 18S rDNA gene and amplifying a 183-bp fragment. Microsporum canis was identified from all samples. The PCR protocol described in the present work demonstrated a 100% concordant result comparing the molecular characterisation with phenotypic characterisation of dermatophytes...
May 2007: Mycoses
Jena C Berg, Kirsten L Hamacher, Glenn D Roberts
BACKGROUND: A 65-year-old woman with a history of liver and kidney transplantation presented with a pruritic and tender rash of 2-year duration on her left knee. METHODS: The patient had a physical examination, and multiple skin biopsies were performed. RESULTS: Examination showed a cluster of dome-shaped, violaceous papules. A skin biopsy specimen showed multiple granules containing basophilic material within the superficial to mid dermis...
May 2007: Journal of Cutaneous Pathology
Jaime Martorell, Nuria Gallifa, Dolors Fondevila, Rosa M Rabanal
A case of a dwarf hamster with two progressively growing nodules on the right fore limb is described. These were excised following ineffective medical treatment and were submitted for histopathological examination, which revealed bacterial pseudomycetoma in both nodules. To the authors' knowledge this is the first reported case of bacterial pseudomycetoma in a dwarf hamster.
December 2006: Veterinary Dermatology
Sasha C Kramer, Michael Ryan, Paul Bourbeau, William B Tyler, Dirk M Elston
We describe mycetoma caused by Microsporum canis occurring in a 9-year-old African-American girl. Pathologic evaluation showed a granulomatous dermatitis with numerous large fungal grains containing septate hyphae that were Fontana-Masson positive. Two cultures of pure grains grew M. canis. Mycetoma due to dermatophytes is very uncommon. The few instances reported have been pseudomycetoma (grains in the absence of sinus tracts). Our patient developed sinus tracts (true mycetoma). No prior reports were found of M...
September 2006: Pediatric Dermatology
Syed Sohail Ali, Afia Zafar, Suhail Muzaffar, Fawad Aslam, Javaid A Khan
Gynecomastia is the most common cause of breast enlargement in males. Trichophyton rubrum is a common dermatophyte, is responsible for a variety of infections, and may rarely manifest as a dermatophytic pseudomycetoma. We report the case of a 52-year-old man who presented with progressive bilateral breast enlargement. This is the first reported case of bilateral breast pseudomycetoma due to T. rubrum. Long-term antifungal therapy with itraconazole was successful.
April 2006: Breast: Official Journal of the European Society of Mastology
L Carrasco, J Pérez
Histopathological analysis demonstrates the morphology of the fungi and shows their relationship with tissue lesions, which is a valuable information in the diagnosis of veterinary mycoses, especially in superficial infections where reservoirs make difficult the diagnosis using other techniques. On the other hand, histopathological analysis should be complementary to other methods such as culture, immunohistochemistry, serology, PCR, etc. In this work, the most relevant histopathological features of some of the most common mycoses of domestic animals, some of which have zoonotic potential, are described and their differential diagnosis is discussed...
March 2000: Revista Iberoamericana de Micología
M Dell'Orco, A Canti, E Pogliani, W Bertazzolo
No abstract text is available yet for this article.
August 2004: Journal of Small Animal Practice
Kurt Zimmerman, Bernard Feldman, John Robertson, Erin S Herring, Thomas Manning
A 1-year-old spayed female Persian cat with alopecia and weight loss had numerous variably ulcerated dermal nodules. Cytologic examination of an aspirate of one of the nodules revealed pyogranulomatous inflammation along with septate hyphae and basophilic round bodies, 0.5-1.0 microm in diameter, surrounded by a thin clear halo (arthrospores). The cytologic diagnosis was dermatophytic pseudomycetoma. Histologically, there were dermal granulomas containing poorly staining, septate hyphae with bulbous spores embedded within abundant amorphous eosinophilic material (Splendore-Hoeppli reaction), and the histologic diagnosis was pseudomycetoma-associated chronic multifocal severe granulomatous dermatitis with lymphocytic perifolliculitis and furunculosis...
2003: Veterinary Clinical Pathology
Zülal Erbağci
Two patients presenting with subcutaneous nodules, plaques, papules and ulceration caused by dermatophytes are described in this report. The first case was atopic and had used low dose systemic corticosteroids intermittently for his asthma. The second case was a poorly controlled and long-standing diabetic patient. The diagnoses were suspected after direct microscopical examinations of the discharge materials which revealed the presence of hyaline hyphae and spores, and histological examination which showed an inflammatory infiltrate with fungal elements in the dermis...
2002: Mycopathologia
R Bond, A M Pocknell, C E Tozet
An eight-year-old neutered female Persian cat with a four-year history of relapsing skin disease, characterised by ulcerated nodules with a yellow granular discharge, was examined. A diagnosis of granulomatous dermatitis and panniculitis (pseudomycetoma) caused by Microsporum canis was made on the basis of history, clinical signs, histopathological examination of skin biopsy specimens and culture of macerated tissue. Because previous therapy, comprising repeated surgical excision and the administration of griseofulvin and itraconazole, had not been successful, terbinafine was administered for an eight-month period...
November 2001: Journal of Small Animal Practice
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