keyword
https://read.qxmd.com/read/32485288/the-role-of-orexin-a-levels-in-epileptic-seizure
#21
JOURNAL ARTICLE
Halil Ibrahim Çikriklar, Dilcan Kotan, Murat Yücel, Mustafa Ceylan, Gönül G Çiftçi, Ömer F Bayraktutan, Ihsan H Çiftçi
BACKGROUND: The aim of this study is to determine the usefulness of Orexin-A levels in differentiating between epileptic seizures and psychogenic non-epileptic seizures in patients presenting to the emergency service with epileptic seizure-type symptoms. METHODS: A total of 80 individuals were included in this study, including 59 who presented to the emergency service within the first four hours of having been diagnosed with generalized tonic-clonic seizures (39 with epileptic seizures (ES) and 20 with pseudoseizures (PNES) and 21 controls...
August 24, 2020: Neuroscience Letters
https://read.qxmd.com/read/32340688/a-case-of-clinical-scholarship
#22
EDITORIAL
Schuyler W Henderson
A 32-year-old child and adolescent psychiatry resident with a history of presenting an abstract at a local psychiatric conference during residency and fourth authorship on an immunotherapy paper from a summer internship during medical school presents with a new-onset desire to write a case report. She has just come off her consultation liaison rotation, during which she consulted on a 12-year-old boy with attention-deficit/hyperactivity disorder, oppositional defiant disorder, disruptive mood dysregulation disorder, and low depressive state hospitalized for pseudoseizures, a new-onset inability to walk, and aggressive outbursts...
May 2020: Journal of the American Academy of Child and Adolescent Psychiatry
https://read.qxmd.com/read/32014624/international-multicenter-studies-on-psychogenic-nonepileptic-seizures-a-systematic-review
#23
REVIEW
Ali A Asadi-Pooya
The aim of the current paper is to systematically review the literature on the existing international multicenter studies on various aspects of PNES and to highlight their findings and significance. I searched the electronic database PubMed for articles that included any of these search terms: Non-epileptic seizures, Nonepileptic seizures, Pseudoseizures, Non-epileptic events, Nonepileptic events, Dissociative seizures, Psychogenic, PNES, AND "international" or "multicenter" or "cross cultural", in their abstracts and titles and published before August 6, 2019...
January 25, 2020: Psychiatry Research
https://read.qxmd.com/read/31645005/semiological-classification-of-psychogenic-nonepileptic-seizures-a-systematic-review-and-a-new-proposal
#24
JOURNAL ARTICLE
Ali A Asadi-Pooya
PURPOSE: A semiological classification of psychogenic nonepileptic seizures (PNES) may help address proper diagnosis and management and also provide standardization for future studies. The aim of the current paper was to systematically review the literature on the proposed classification systems for the semiology of PNES and to provide a new proposal based on the best available evidence. METHODS: I searched the electronic database PubMed on May 16, 2019 for articles that included the following search terms: "psychogenic" AND "semiology" or "classification" and also "nonepileptic" AND "semiology" or "classification" and also "pseudoseizure" AND "semiology" or "classification" since 1940...
November 2019: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/31403020/a-case-report-of-schizoaffective-disorder-with-pseudoseizures-in-a-42-year-old-male
#25
Emmanuel Tito, Blayne Knapp, Anthony Bucca, Eduardo D Espiridion
Psychogenic nonepileptic seizures (PNES), historically referred to as pseudoseizures or hysterical seizures, are sudden disturbances of motor, sensory, autonomic, cognitive, or emotional functions that can mimic epileptic seizures. PNES have a psychologic etiology related to dissociative disorders or conversion disorders, as opposed to the abnormally excessive neuronal activity found in epileptic seizures. Psychosocial conflicts are essentially converted into physical symptoms, resulting in seizure-like symptoms...
June 5, 2019: Curēus
https://read.qxmd.com/read/31062104/ozone-therapy-for-complex-regional-pain-syndrome-review-and-case-report
#26
REVIEW
Robert Jay Rowen, Howard Robins
PURPOSE OF REVIEW: The world faces a crisis in pain management. CRPS is a multifaceted painful disorder, which is difficult to treat and resolve. Ozone therapy has unique mechanisms of actions that may directly address the emerging discoveries of factors related to pathogenesis of the disorder and other pain conditions. These include oxygenation, immune modulation, anti-infective properties, and anti-inflammatory properties. This review is to present ozone therapy as a novel approach for pain treatment, including CRPS...
May 6, 2019: Current Pain and Headache Reports
https://read.qxmd.com/read/30915765/paroxysmal-non-epileptic-events-in-the-pediatric-emergency-department
#27
JOURNAL ARTICLE
D Buonsenso, M Plosnic, G Bersani, S Monaco, P Ferrara, A Chiaretti
Paroxysmal non-epileptic events (PNEs), or pseudoseizures (PS) resemble epileptic seizures. They are considered part of a personality disorder and have a higher incidence among adolescents. Patients describe episodes (lasting up to 20 minutes) of loss of consciousness, twitching or jerking and unusual emotional states. Unlike epileptic seizures, they are not associated with electroencephalographic abnormalities. Distinguishing epileptic seizures from PNEs is not easy. 20% of patients with seizures have a final PNEs diagnosis but recognizing them on the first examination is difficult...
March 2019: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/30868115/functional-seizures-an-evaluation-of-the-attitudes-of-general-practitioners-local-to-a-tertiary-neuroscience-service-in-london
#28
JOURNAL ARTICLE
Mahinda Yogarajah, Ruth Child, Niruj Agrawal, Sarah Cope, Mark Edwards, Marco Mula
OBJECTIVE: Functional seizures are a common functional neurologic disorder. Given their chronic nature, and the biopsychosocial factors involved in their etiology, general practitioners (GPs) play a crucial role in the care of these patients. However, little is known about the attitudes of GPs toward, and knowledge of, functional seizures. METHODS: The Atkinson Morley Regional Neuroscience Centre in London provides a comprehensive service to patients with functional seizures...
March 2019: Epilepsia Open
https://read.qxmd.com/read/30860006/96-the-cat-s-meow-feline-warning-of-imminent-seizures
#29
JOURNAL ARTICLE
Chevelle R Winchester, Emeto B Chioma, Alan R Hirsch
Study ObjectiveCats may respond to seizures with a threat response (Strong, 1999). Detailed description of this for seizures or pseudoseizures has not heretofore been described. METHOD: Case study: A 29-year-old right handed female, two years prior to presentation, developed onset of seizures which last approximately one minute, almost on a daily basis. These are associated with shortness of breath and postictal blurred vision. During these epoch, she would experience temporary amnesia; a feeling as if she had lost a couple years of memory which gradually returned within an hour...
February 2019: CNS Spectrums
https://read.qxmd.com/read/30747509/neurologic-conditions-new-onset-seizures-in-adults
#30
JOURNAL ARTICLE
James E McKinley, Allen Perkins
Family physicians may be the first point of contact for adults with new-onset seizure. There are many etiologies of seizures in adults. Etiologies of provoked seizures include temporary metabolic disturbances, central nervous system infections, cerebrovascular disease, drug withdrawal, and traumatic brain injury. Stable or evolving cerebral conditions can cause unprovoked seizures. Nonorganic etiologies include nonepileptiform convulsions, such as a pseudoseizure, which are psychogenic. In the emergency department setting, computed tomography scan of the head should be considered for all patients with new-onset seizure...
February 2019: FP Essentials
https://read.qxmd.com/read/30365439/emergency-department-presentation-of-a-new-onset-seizure-a-case-report
#31
JOURNAL ARTICLE
Benjamin J Miller
A seizure is a symptom of brain dysfunction, resulting in 1.6 million emergency department visits each year. The evaluation of new seizures in the emergency department is a process looking for triggers of seizures such as toxins, mass lesions, or metabolic derangements. Maintaining a broad differential diagnosis is essential to prevent premature closure of the diagnostic evaluation. Timing of neurologic imaging and electroencephalogram depends on the clinical situation. In this case, a young woman presents with a "new-onset" seizure with subsequent elevation of white blood cells and serum lactate levels...
October 2018: Advanced Emergency Nursing Journal
https://read.qxmd.com/read/28753046/levetiracetam-in-toxic-seizures
#32
JOURNAL ARTICLE
Ted Lee, Brandon J Warrick, Preeyaporn Sarangarm, Robert L Alunday, Silas Bussmann, Susan C Smolinske, Steven A Seifert
BACKGROUND/OBJECTIVES: The use of levetiracetam (LEV) in the management of drug-induced seizures has not been systematically investigated. Repetitive and continuous seizures that do not respond to benzodiazepines require second line therapy. Levetiracetam has a unique receptor binding site, rapid absorption, no known cardiac effects at therapeutic doses, and is theoretically a good candidate for use in drug-induced seizures. We evaluate the safety of LEV and its association with seizure cessation in this retrospective chart review of patients who received LEV as a control agent in drug-induced seizures...
March 2018: Clinical Toxicology
https://read.qxmd.com/read/28458436/response-to-eperisone-in-patients-of-therapy-resistant-dissociative-convulsions-a-report-of-two-cases
#33
JOURNAL ARTICLE
Vijendra Nath Jha, Pramod Kumar Singh
Dissociative convulsions or pseudoseizures are a difficult to treat common psychiatric condition. In a subset of these patients, the chief complaint is clenching of teeth with apparent nonresponsiveness alone. Neither drugs nor psychotherapeutic interventions have been found to be of much help in its management. Report of two such subsets of cases is presented, in which patients with dissociative convulsions showed sudden, dramatic, and sustained good response to the addition of a muscle relaxant eperisone.
January 2017: Indian Journal of Pharmacology
https://read.qxmd.com/read/27394057/psychogenic-non-epileptic-seizures-pnes-on-the-internet-online-representation-of-the-disorder-and-frequency-of-search-terms
#34
JOURNAL ARTICLE
Lorna Myers, Jace Jones, Nadine Boesten, Marcelo Lancman
PURPOSE: The nature of the symptoms associated with PNES require a multidisciplinary health team. There are too few professionals with an adequate understanding of PNES and therefore many are not able to provide patients with necessary information. In the age of the internet, it is not surprising that patients or caregivers might look for answers online. The purpose of this project was to investigate the online representation of PNES and search frequency for PNES and its associated terms...
August 2016: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/27343796/psychogenic-non-epileptic-seizures-in-the-post-anesthesia-recovery-unit
#35
JOURNAL ARTICLE
Juan A Ramos, Sorin J Brull
INTRODUCTION: Psychogenic non-epileptic seizures (PNES or "pseudoseizures") remain an obscure topic in the peri-operative setting. They are sudden and time-limited motor and cognitive disturbances, which mimic epileptic seizures, but are psychogenically mediated. Pseudoseizures occur more frequently than epilepsy in the peri-operative setting. Early diagnosis and management may prevent iatrogenic injury. CASE: 48 year-old female with a history of depression and "seizures" presented for gynecologic surgery...
July 2016: Brazilian Journal of Anesthesiology
https://read.qxmd.com/read/27061640/outlining-the-psychopathology-behind-a-case-of-conversion-syndrome-is-a-holistic-approach-beneficial
#36
JOURNAL ARTICLE
Francesca Falzon Aquilina, Daniel Vella Fondacaro
Conversion disorder refers to a set of symptoms where no relevant organic cause is found. These include sensory/motor disturbances, and other neurological symptoms, such as pseudoseizures. Patients with this condition may, by having it, achieve a primary or secondary gain. The condition should be diagnosed when all the relevant investigations are inconclusive. In this case, we use the bio-psycho-social model for the interpretation and guidance of treatment. We also demonstrate how a holistic approach is beneficial when it comes to a multi-dimensional interpretation of such a case...
March 2016: PsyCh Journal
https://read.qxmd.com/read/26994361/insomnia-in-epilepsy-is-associated-with-continuing-seizures-and-worse-quality-of-life
#37
JOURNAL ARTICLE
Mark Quigg, Sean Gharai, Jeff Ruland, Catherine Schroeder, Matthew Hodges, Karen S Ingersoll, Frances P Thorndike, Guofen Yan, Lee M Ritterband
PURPOSE: To evaluate how insomnia is associated with seizure control and quality of life in patients with epilepsy. METHODS: Consecutive patients with epilepsy attending clinical visits were surveyed with the Insomnia Severity Index (ISI). Patients had to be treated with at least one anticonvulsant and could not have had documented psychogenic pseudoseizure. The presence or absence of seizures and quality of life (QOLIE-P-10) within the past 4 weeks was recorded...
May 2016: Epilepsy Research
https://read.qxmd.com/read/26966367/medical-management-of-epileptic-seizures-challenges-and-solutions
#38
REVIEW
Anand K Sarma, Nabil Khandker, Lisa Kurczewski, Gretchen M Brophy
Epilepsy is one of the most common neurologic illnesses. This condition afflicts 2.9 million adults and children in the US, leading to an economic impact amounting to $15.5 billion. Despite the significant burden epilepsy places on the population, it is not very well understood. As this understanding continues to evolve, it is important for clinicians to stay up to date with the latest advances to provide the best care for patients. In the last 20 years, the US Food and Drug Administration has approved 15 new antiepileptic drugs (AEDs), with many more currently in development...
2016: Neuropsychiatric Disease and Treatment
https://read.qxmd.com/read/26578475/-conversion-disorder-in-children-and-adolescents
#39
REVIEW
Paula Andrea Duque, Rafael Vásquez, Miguel Cote
BACKGROUND: Conversion disorder is diagnosed late, by exclusion and with a high risk of complications. There is a wide experience in adults that is not extrapolated to paediatric patients. According to the literature, the prognosis is better in children, but this changes when other variables such are included, such as comorbidities, late diagnosis and a very convincing social image of the neurological disease. OBJECTIVE: To review the medical literature on the clinical features, diagnosis, comorbidities and treatment of this disorder...
October 2015: Revista Colombiana de Psiquiatría
https://read.qxmd.com/read/26468371/a-fitting-tribute-to-epilepsia-partialis-continua
#40
Priyank Patel, Nirav Amin, Shreya B Patel, Catrin Morgan
In July 2014, a 66 year-old lady presented to emergency department after having not been seen for 3 days. She was eventually found in bed not responding verbally. The ambulance service reported tonic-clonic seizures lasting 10-30 s every 3 min. The patient was treated for her seizures with phenytoin and additional benzodiazepines as required. Her seizure had temporarily resolved and she was admitted for investigations. She had no history of epilepsy or seizures. The history of alcoholism and lack of any substantial history of epilepsy, left the team considering whether this was an alcohol induced event or a pseudoseizure...
September 2015: Annals of Medicine and Surgery
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