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Erysipelas

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https://www.readbyqxmd.com/read/29222939/which-outcomes-are-reported-in-cellulitis-trials-results-of-a-review-of-outcomes-included-in-cellulitis-trials-and-a-patient-priority-setting-survey
#1
REVIEW
E Smith, M Patel, K Thomas
BACKGROUND: There is an emerging need to develop consistent outcomes in clinical trials to allow effective comparison of treatment effects. No systematic review has previously looked at the reporting of outcome measures used in randomised controlled trials (RCTs) on treatment and prevention of cellulitis (erysipelas). OBJECTIVES: The primary aim of this review was to describe the breadth of outcomes reported from RCTs on cellulitis treatment and prevention. The secondary aim was to identify outcome themes from patient and health care professionals' feedback from a cellulitis priority setting partnership (PSP)...
December 9, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29196173/characterization-of-pathogenic-roles-of-two-erysipelothrix-rhusiopathiae-surface-proteins
#2
Weifeng Zhu, Chengzhi Cai, Jingjing Huang, Liang Liu, Zhongmin Xu, Xiaomei Sun, Meilin Jin
Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. E. rhusiopathiae HP0728 and HP1472 have been reported to be down regulated in low-virulence or avirulent strains, but their pathogenic roles are not known. In this study, it was found that E. rhusiopathiae HP0728 and HP1472 were displayed on the surface of E. rhusiopathiae. Moreover, recombinant HP1472 could adhere to pig vascular endothelial cells. Recombinant HP0728 could bind host plasminogen but could not bind fibronectin...
November 28, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29184984/-charcot-foot-masked-by-erysipelas-and-peripheral-arterial-disease
#3
A Haep, S Murday, A Risse, D Nashan, H F Ständer
Charcot foot is also known as Charcot disease or Charcot arthropathy. The associated aseptic destruction of the bones and joints of the foot results due to peripheral neuropathy accompanied by impaired pain perception, impaired vasomotricity with increased vasodilation, and an unequal weight distribution. Because it is frequently diagnosed late and, thus, incorrectly treated, serious complications often result. An 86-year-old man in poor health was diagnosed with erysipelas of the right foot. The foot was glossy and edematously swollen, showing necrosis of the distal phalanx of the third toe...
November 28, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29160213/cutaneous-metastases-of-internal-malignancies-an-experience-from-a-single-institution
#4
Elena Guanziroli, Antonella Coggi, Luigia Venegoni, Daniele Fanoni, Giulia Ercoli, Francesca Boggio, Stefano Veraldi, Emilio Berti, Raffaele Gianotti, Stefano Ferrero, Alessandro Del Gobbo
BACKGROUND: Cutaneous metastases represent 2% of all skin tumours. Their recognition can be challenging, as they may present with different clinical features, with consequent frequent delay and failure in diagnosis. OBJECTIVES: To review our series of cutaneous metastatic lesions, analyse their frequency according to patient gender, histotype, localization of the primary tumour, and site of cutaneous metastasis, and correlate this data with clinicopathological parameters...
November 21, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29090420/soft-tissue-infection-secondary-to-cellulitis-killed-st-john-of-the-cross-1542-1591
#5
Raffaella Bianucci, Otto Appenzeller, Peter Evans, Philippe Charlier, Antonio Perciaccante
PURPOSE: St. John of the Cross (1542-1591) died aged 49 years after 3 months of excruciating pain following a trivial lesion in his right foot. Erysipelas, a superficial bacterial infection of the skin, and subsequent sepsis were previously suggested as the cause of his death. Here, an alternative diagnosis is proposed. METHODS: An accurate perusal of his biography allowed the symptomatology, the clinical evolution, the depth of the infection and the associated systemic manifestations displayed by Fray John to be reconstructed...
October 31, 2017: Infection
https://www.readbyqxmd.com/read/29080837/genotype-phenotype-correlation-in-fmf-patients-a-non-classic-recessive-autosomal-or-atypical-dominant-autosomal-inheritance
#6
V Procopio, S Manti, G Bianco, G Conti, A Romeo, F Maimone, T Arrigo, M C Cutrupi, C Salpietro, C Cuppari
BACKGROUND: Uncertainty remains on the pathogenetic mechanisms, model of inheritance as well as genotype-phenotype correlation of FMF disease. OBJECTIVE: To investigate the impact of genetic factors on the FMF phenotype and the disease inheritance model. METHODS: A total of 107 FMF patients were enrolled. Patients were diagnosed clinically. All patients underwent genetic analysis of the FMF locus on 16p13.3. RESULTS: 9 distinct mutations were detected...
January 30, 2018: Gene
https://www.readbyqxmd.com/read/29079067/clinical-mimics-an-emergency-medicine-focused-review-of-cellulitis-mimics
#7
Garrett Blumberg, Brit Long, Alex Koyfman
BACKGROUND: Cellulitis is a common clinical condition with low rates of morbidity and mortality if treated appropriately. Mimics of cellulitis presenting with erythema, edema, warmth, and pain can be associated with grave morbidity and mortality if misdiagnosed. OBJECTIVE: This review investigates the signs and symptoms of cellulitis, mimics of cellulitis, and an approach to the management of both cellulitis and its mimics. DISCUSSION: The current emergency medicine definition of cellulitis includes erythema, induration, warmth, and swelling...
October 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29038054/characterization-of-roles-of-spaa-in-erysipelothrix-rhusiopathiae-adhesion-to-porcine-endothelial-cells
#8
Weifeng Zhu, Chengzhi Cai, Ya Wang, Jingtao Li, Chao Wu, Chao Kang, Xiaomei Sun, Meilin Jin
Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. The major protective antigen SpaA was suggested to play important roles in E. rhusiopathiae adhesion to host cells, but there is no specific study on SpaA pathogenic roles in adhesion. In this study we characterized direct and indirect roles of SpaA in E. rhusiopathiae adhesion to porcine endothelial cells. Recombinant E. rhusiopathiae SpaA (rSpaA) successfully binded to porcine iliac arterial endothelial cells. rSpaA protein pre-incubating endothelial cells or rSpaA antiserum pre-incubating E...
October 14, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29026615/an-unusual-cutaneous-infection-caused-by-mycobacterium-marinum
#9
Federica Veronese, Elisa Zavattaro, Pamela Farinelli, Enrico Colombo, Paola Savoia
Introduction.Mycobacterium marinum is a non-tubercular mycobacterium residing in fresh or salt water (in tropical or temperate areas); it is a fish and human pathogen, and in immunocompromised patients can cause severe cutaneous and subcutaneous infections. Case presentation. A 46-year-old white man who underwent immunosuppressive therapy was admitted to our department in May 2016 for skin lesions previously diagnosed as 'unusual erysipelas'. We rejected the hypothesis of erysipelas, due to the clinical features, and our diagnostic hypotheses were oriented towards sporotrichosis, atypical mycobacteriosis, cutaneous tuberculosis and cutaneous sarcoidosis...
April 2017: JMM Case Reports
https://www.readbyqxmd.com/read/28992840/-compression-is-important-in-erysipelas-treatment
#10
EDITORIAL
Maja Villefrance, Annette Høgh, Lena Hagelskjær Kristensen
Erysipelas is a common skin infection involving the lymphatic vessels, which induces an oedema. This has a tendency of persisting after infection is treated. The lymphatic system plays an important role in the immune system, and the impaired lymph drainage leads to a state of local immune deficiency. This is essential to the pathogenesis of recurrent erysipelas, as each episode of erysipelas further damages the lymphatic system and increases the risk of a new infection. This vicious circle makes it important to treat both erysipelas and oedema appropriately to reduce recurrence and morbidity...
October 9, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28976997/transcription-analysis-of-the-responses-of-porcine-heart-to-erysipelothrix-rhusiopathiae
#11
Chao Kang, Qiang Zhang, Weifeng Zhu, Chengzhi Cai, Xiaomei Sun, Meilin Jin
Erysipelothrix rhusiopathiae (E. rhusiopathiae) is the causative agent of swine erysipelas. This microbe has caused great economic losses in China and in other countries. In this study, high-throughput cDNA microarray assays were employed to evaluate the host responses of porcine heart to E. rhusiopathiae and to gain additional insights into its pathogenesis. A total of 394 DE transcripts were detected in the active virulent E. rhusiopathiae infection group compared with the PBS group at 4 days post-infection...
2017: PloS One
https://www.readbyqxmd.com/read/28932317/ventral-abdominal-hernia
#12
Georgi Tchernev, Anastasiya Chokoeva, Jacopo Lotti, Katlein França, Torello Lotti
A 63-year-old Caucasian female patient presented with redness of the both foot and lower legs, as well as edema of the left lower leg, accompanied by subjective complaints of burning. Fever was not reported. Well-circumscribed oval shaped tumor formation was revealed also on the abdominal wall, with hyperpigmented and depigmented areas on its ulcerated surface, measuring approximately 10/10cm in diameter, with soft-elastic texture on palpation. The lesion occurred in 2011, according to the patient's history...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28887216/phytochemistry-pharmacology-quality-control-and-future-research-of-forsythia-suspensa-thunb-vahl-a-review
#13
REVIEW
Zhaoyi Wang, Qing Xia, Xin Liu, Wenxue Liu, Wanzhen Huang, Xue Mei, Jun Luo, Mingxu Shan, Ruichao Lin, Dixin Zou, Zhiqiang Ma
ETHNOPHARMACOLOGICAL RELEVANCE: Forsythiae Fructus (called Lianqiao in Chinese), the fruit of Forsythia suspensa (Thunb.) Vahl, is utilized as a common traditional medicine in China, Japan and Korea. It is traditionally used to treat pyrexia, inflammation, gonorrhea, carbuncle and erysipelas. Depending on the different harvest time, Forsythiae Fructus can be classified into two forms, namely Qingqiao and Laoqiao. The greenish fruits that start to ripen are collected as Qingqiao, while the yellow fruits that are fully ripe are collected as Laoqiao...
September 5, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28879609/-bacterial-skin-and-soft-tissue-infections
#14
REVIEW
Frank Hanses
Bacterial skin and soft tissue infections are frequent and represent one of the most important differential diagnoses in patients presenting with reddened and swollen skin and soft tissue. Among these infections, cellulitis (phlegmon), erysipelas and abscesses are the most frequent. Whereas erysipelas is almost exclusively caused by streptococci and can be successfully treated with penicillin, an effective antibiotic therapy targeted at Staphylococcus aureus should be empirically considered for abscesses and phlegmon; other pathogens, such as gram negative and anaerobic bacteria can be found in patients with the corresponding underlying disease and certain risk factors...
November 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28838924/elephantiasis-nostras-verrucosa-secondary-to-recurrent-erysipelas
#15
Alexandra Freitas, Jorge Filipe Miranda Rodrigues
No abstract text is available yet for this article.
August 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28831302/cutaneous-infection-and-bactaeremia-caused-by-erwinia-billingiae-a-case-report
#16
M Prod'homme, L A Micol, S Weitsch, J-L Gassend, O Martinet, C Bellini
Cellulitis and erysipelas are common skin infections usually caused by Staphylococcus aureus and streptococci. Gram-negative rods are rarely implicated. We report here a case of dermohypodermitis and bactaeremia caused by Erwinia billingiae, a Gram-negative bacteria usually pathogenic and epiphytic to pome fruit tree.
September 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/28794379/bilateral-milian-s-ear-sign-of-erysipelas
#17
Kiyozumi Suzuki, Hiromasa Otsuka
No abstract text is available yet for this article.
September 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28748022/-primary-congenital-lymphedema-milroy-disease-the-first-case-observed-in-the-department-of-pediatrics-at-the-university-hospital-yalgado-ouedraogo-ouagadougou
#18
Chantal Zoungrana Ouattara, Angèle Kalmogho, Caroline Yonaba, Chantal Gabrielle Bouda, Ghislaine Yaméogo, Ludovic Kam
Congenital lymphedema is the accumulation of lymphatic fluid in the child's interstitial spaces. Milroy disease is a rare, hereditary, autosomal dominant condition showing incomplete penetrance. We report the case of a 7-year old little girl with Milroy disease examined for erysipelas on congenital big right leg. A family history of large congenital member existed. Physical examination showed big oedematous right leg painful to palpation, with skin lichenification and erysipelas. Paraclinical assessment objectified cutaneous lymphedema with vascular involvement suggestive of ectasia of the right saphenous vein...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28741584/pitfall-of-modern-genetics-recurrent-erysipelas-masquerading-as-autoinflammatory-disease
#19
E J W Spierings, J W M van der Meer, A Simon
A patient presented with recurrent episodes of fever and skin rash for eight years. DNA analysis of the NLRP3 gene revealed a mutation associated with autoinflammatory disease. After an initial positive response to the biological anakinra, the patient deteriorated. Reassessment revealed recurrent erysipelas. In conclusion, sometimes erysipelas-like skin rash is real erysipelas, and DNA results are not always the final answer.
July 2017: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/28740776/tc-99m-human-serum-albumin-transit-time-as-a-measure-of-arm-breast-cancer-related-lymphedema
#20
Navid M Toyserkani, Svend Hvidsten, Siavosh Tabatabaeifar, Jane A Simonsen, Poul F Høilund-Carlsen, Jens A Sørensen
BACKGROUND: Lymphoscintigraphy has often been used for evaluating arm lymphatic dysfunction, but no optimal approach for quantification has so far emerged. We propose a quantifiable measure of lymphatic function that we applied in patients treated for breast cancer. METHODS: Eleven patients, aged 34-68 years, with unilateral arm lymphedema following breast cancer treatment underwent bilateral lymphoscintigraphy using intradermal injection in both hands of technetium-99m-labeled human serum albumin and sequential 5 min imaging for 5 hours...
June 2017: Plastic and Reconstructive Surgery. Global Open
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