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Erysipelas

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https://www.readbyqxmd.com/read/28114522/the-myth-of-erysipelas-fire-water-and-blood
#1
Valencia Long
No abstract text is available yet for this article.
January 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28101016/cellulitis-in-a-liver-transplant-patient-as-an-initial-manifestation-of-disseminated-cryptococcal-disease
#2
Marcos Davi Gomes de Sousa, Fred Bernardes Filho, Luís Eduardo Barros Costa Fernandes, Cássia Regina Guedes Leal, Cristiane Rocha Magalhães, Marcos Antonio Custódio Neto da Silva, Halime Silva Barcaui
A 50-year-old male underwent liver transplantation due to cryptogenic cirrhosis and was admitted with severe pain in the left leg as well as phlogosis. Amoxicillin/clavulanic acid was prescribed, assuming bullous erysipelas. Among the tests performed, the latex agglutination test for the Cryptococcus sp. antigen was positive, and in both the blood culture and blister culture Cryptococcus sp. was isolated. Daily fluconazole was started. Even though liposomal amphotericin B has been started on the fifth day of hospitalization, the patient progressed to death...
September 2016: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28050545/intraosseous-anomalous-drainage-a-rare-case-of-pretibial-varicose-vein
#3
Frederico Barra de Moraes, Carolina Parreira Ribeiro Camelo, Marcelo Luiz Brandão, Pedro Ivo Fávaro, Tercília Almeida Barbosa, Raul Carlos Barbosa
Valve failure with reflux and post-thrombotic syndrome are the factors most commonly correlated with varicose disease. Other rare etiologies can be put forward when these two main causes are ruled out. We report a case in which a young man presented chronic pain in the left tibia, varicose veins in the lower limbs and frequent occurrences of erysipelas. During investigation of the etiology of the varicose veins, radiographs and magnetic resonance imaging of the left leg were requested. These showed images suggestive of an osteolytic lesion in the tibia, but led us to the diagnosis of an intraosseous vein with anomalous drainage...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/27999691/evolution-of-skin-during-rehabilitation-for-elephantiasis-using-intensive-treatment
#4
Henrique Jose Pereira de Godoy, Ricardo Budtinger Filho, Maria de Fatima Guerreiro Godoy, José Maria Pereira de Godoy
The objective of this study is to describe the evolution of the skin during rehabilitation for elephantiasis using intensive treatment. We report on the case of a 55-year-old patient with a seven-year history of leg edema. The patient reported that it began with repeated outbreaks of erysipelas over several years. One leg evolved with significant edema leading to an inability to ambulate and for about one month the patient said that he could not get out of bed. Moreover the patient was obese weighing 130 kilos and with a BMI of 39...
2016: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/27986736/efficacy-and-safety-of-wuling-san-for-treatment-of-breast-cancer-related-upper-extremity-lymphoedema-study-protocol-for-a-pilot-trial
#5
Huiru Zhu, Zheng Peng, Meiyu Dai, Yan Zou, Fengxian Qin, Jifei Chen, Liuying Song, Baoyu He, Xiaolan Lv, Shengming Dai
INTRODUCTION: Breast-cancer-related upper extremity lymphoedema (BCUL), a common complication of mastectomy, can cause physical discomfort, psychological distress, cosmetic defects, functional disability and chronic recurrent erysipelas in the affected arm(s). It is a challenge to physicians involved in the management of these patients. Wuling San, a classic prescription in Traditional Chinese Medicine used in treating oedema for thousands of years, is reported by many Chinese journals to perform well in BCUL...
December 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27873166/a-dangerous-hobby-erysipelothrix-rhusiopathiae-bacteremia-most-probably-acquired-from-freshwater-aquarium-fish-handling
#6
E Asimaki, O Nolte, G Overesch, C Strahm
Erysipelothrix rhusiopathiae is a facultative anaerobic Gram-positive rod that occurs widely in nature and is best known in veterinary medicine for causing swine erysipelas. In humans, infections are rare and mainly considered as occupationally acquired zoonosis. A case of E. rhusiopathiae bacteremia most likely associated with home freshwater aquarium handling is reported. The route of transmission was probably a cut with the dorsal fin of a dead pet fish. A short review of clinical presentations, therapeutic considerations and pitfalls of E...
November 21, 2016: Infection
https://www.readbyqxmd.com/read/27786163/evaluation-of-anti-erysipelothrix-rhusiopathiae-igg-response-in-bottlenose-dolphins-tursiops-truncatus-to-a-commercial-pig-vaccine
#7
Hendrik H Nollens, Luis G Giménez-Lirola, Todd R Robeck, Todd L Schmitt, Stacy DiRocco, Tanja Opriessnig
Erysipelothrix rhusiopathiae is the causative agent of erysipeloid in humans and of erysipelas in various animals, including bottlenose dolphins Tursiops truncatus, in which an infection has the potential to cause peracute septicemia and death. The purpose of this study was to evaluate the efficacy of using an off-label porcine (ER BAC PLUS®, Zoetis) E. rhusiopathiae bactrin in a bottlenose dolphin vaccination program by determining the anti-E. rhusiopathiae antibody levels in vaccinated dolphins over a 10 yr period...
October 27, 2016: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/27782864/familial-mediterranean-fever-patients-may-have-unmet-need-for-treatment-of-erysipelas-like-erythema
#8
Mehmet Engin Tezcan
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October 25, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27773881/pathogenic-characterization-of-erysipelothrix-rhusiopathiae-met-203-type-spaa-strains-from-chronic-and-subacute-swine-erysipelas-in-japan
#9
Mariko Uchiyama, Yohko Shimazaki, Yukari Isshiki, Akemi Kojima, Fumiya Hirano, Kinya Yamamoto, Mayumi Kijima, Hidetaka Nagai
To characterize the Erysipelothrix rhusiopathiae Met-203 type surface protective antigen (Spa) A strains causing swine erysipelas in Japan, the nucleotide sequence of the hypervariable region of the spaA gene was determined in 80 E. rhusiopathiae (serotype 1a) isolates collected from pigs with chronic and subacute swine erysipelas in 14 prefectures in 2008-2014. In this study, 14 (17.5%) isolates were Met-203 type SpaA strains. We confirmed the pathogenicity of a Met-203 type SpaA strain in specific-pathogen-free pigs...
January 20, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/27767278/wells-syndrome
#10
REVIEW
Andreas Benedikt Weins, Tilo Biedermann, Tina Weiss, Johannes Martin Weiss
A rare eosinophilic dermatosis, Wells syndrome, also referred to as eosinophilic cellulitis, is characterized by great clinical variability. Typical findings include infiltrated erythematous plaques arising on the extremities. Lesions initially resemble erysipelas/cellulitis, however, they do not improve with antibiotic treatment. Eosinophilic cellulitis is a diagnosis of exclusion that may only be made over the course of the disease, taking into account clinical and characteristic histological findings (flame figures)...
October 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27765000/how-to-treat-a-fulminant-erysipelas-and-sepsis-caused-by-myroides-odoratimimus-case-report-and-literature-review
#11
Philippe Willems, Jan Muller, Jan Verhaegen, Veroniek Saegeman, Stefanie Desmet
We report a case of a 77-year old male who developed a fulminant erysipelas and sepsis, caused by Myroides odoratimimus. Selecting the optimal antibiotic therapy for the treatment of infections with M. odoratimimus is challenging due to limited clinical experience with this micro-organism and its reported multidrug-resistance. Review of previous studies concerning in vitro antibacterial susceptibility and clinical experience with M. odoratimimus resulted in six case reports describing bacteremia, soft tissue and bone infections, pneumonia and urinary tract infections...
October 20, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27748083/peficitinib-a-jak-inhibitor-in-the-treatment-of-moderate-to-severe-rheumatoid-arthritis-in-methotrexate-inadequate-responders
#12
A J Kivitz, S R Gutierrez-Ureña, J Poiley, M C Genovese, R Kristy, K Shay, X Wang, J P Garg, A Zubrzycka-Sienkiewicz
OBJECTIVE: To evaluate efficacy and safety of orally administered once-daily peficitinib in combination with methotrexate (MTX) in patients with moderate-to-severe rheumatoid arthritis (RA) who had an inadequate response to MTX. METHODS: In this multinational, phase IIb, randomized, double-blind, placebo-controlled, dose-ranging trial, patients with RA (N=378) were treated with peficitinib 25 mg, 50 mg, 100 mg, 150 mg + MTX, or matching placebo + MTX once daily for 12 weeks (NCT01554696)...
October 16, 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27652151/low-sensitivity-of-needle-aspiration-cultures-in-patients-with-cellulitis-erysipelas
#13
Rein Jan Piso, R Pop, M Wieland, I Griesshammer, M Urfer, U Schibli, S Bassetti
PURPOSE: Cellulitis is normally treated without knowledge of the responsible pathogen. Blood cultures are positive in about 2-4 %, and superficial swabs are of no value. Needle aspiration has been proposed with identifying the likely pathogen in up to 29 %, but these studies are of older date and the technique is not widely used. METHODS: We prospectively evaluated the sensitivity of needle aspiration cultures in all patients with erysipelas/cellulitis. Diagnosis was made clinically by the treating physician...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27612399/autoinflammatory-associated-vasculitis
#14
Shira Ginsberg, Itzhak Rosner, Michel Rozenbaum, Gleb Slobodin, Karina Zilber, Nina Boulman, Lisa Kaly, Abid Awisat, Nizar Jiries, Ofrat Beyar-Katz, Doron Rimar
Autoinflammatory diseases are characterized by recurrent episodes of fever and localized or systemic inflammation and are caused by monogenic defects of innate immunity. The skin is commonly involved with various manifestations including erysipelas like rash and urticaria. Although vasculitis has been described in many autoinflammatory diseases, it has not been recognized as a characteristic feature of these diseases and autoinflammatory diseases are not listed as an etiology for vasculitis associated with a systemic disease in the 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides...
December 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/27591818/-lymphedema-from-diagnosis-to-treatment
#15
S Vignes
Lymphedema results from impaired lymphatic transport with increased limb volume. Lymphedema are divided in primary and secondary forms. Upper-limb lymphedema secondary to breast cancer treatment is the most frequent in France. Primary lymphedema is sporadic, rarely familial or associated with complex malformative or genetic disorders. Diagnosis of lymphedema is mainly clinical and lymphoscintigraphy is useful in primary form to assess precisely the lymphatic function of the two limbs. Erysipelas (cellulitis) is the main complication, but psychological or functional discomfort may occur throughout the course of lymphedema...
August 31, 2016: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/27587513/the-charcot-foot-pathophysiology-diagnosis-and-classification
#16
REVIEW
K Trieb
Neuropathic changes in the foot are common with a prevalence of approximately 1%. The diagnosis of neuropathic arthropathy is often delayed in diabetic patients with harmful consequences including amputation. The appropriate diagnosis and treatment can avoid an extensive programme of treatment with significant morbidity for the patient, high costs and delayed surgery. The pathogenesis of a Charcot foot involves repetitive micro-trauma in a foot with impaired sensation and neurovascular changes caused by pathological innervation of the blood vessels...
September 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27553785/a-retrospective-chart-review-study-to-describe-selected-zoonotic-and-arboviral-etiologies-in-hospitalized-febrile-patients-in-the-republic-of-armenia
#17
Lusine Paronyan, Eduard Zardaryan, Vahe Bakunts, Zaruhi Gevorgyan, Vigen Asoyan, Hripsime Apresyan, Alvard Hovhannisyan, Karo Palayan, Christian T Bautista, Tinatin Kuchuloria, Robert G Rivard
BACKGROUND: Scant information is available on the infectious causes of febrile illnesses in Armenia. The goal of this study was to describe the most common causes, with a focus on zoonotic and arboviral infections and related epidemiological and clinical patterns for hospitalized patients with febrile illnesses of infectious origin admitted to Nork Infectious Diseases Clinical Hospital, the referral center for infectious diseases in the capital city, Yerevan. METHOD: A chart review study was conducted in 2014...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27541818/genomic-and-proteomic-characterization-of-se-i-a-temperate-bacteriophage-infecting-erysipelothrix-rhusiopathiae
#18
Wentao Yuan, Yaning Zhang, Guangcao Wang, Juan Bai, Xianwei Wang, Yufeng Li, Ping Jiang
A bacteriophage infecting pathogenic Erysipelothrix rhusiopathiae was isolated from a swine farm experiencing an outbreak of acute swine erysipelas; we designated this phage SE-I. SE-I has an icosahedral head, a long tail and a double-stranded DNA genome. The 34,997-bp genome has a GC content of 34 % and contains 43 open reading frames (ORFs) encoding packaging, structural, lysin-holin, and hypothetical proteins. Components of purified SE-I were separated using SDS-PAGE and analyzed using liquid chromatography-mass spectrometry...
November 2016: Archives of Virology
https://www.readbyqxmd.com/read/27530088/clinician-reported-lesion-measurements-in-skin-infection-trials-definitions-reliability-and-association-with-patient-reported-pain
#19
John H Powers, Anita F Das, Carisa De Anda, Philippe Prokocimer
OBJECTIVES: Outcome assessments as clinical trial endpoints should be well-defined, reliable, and reflect meaningful treatment benefits. For acute bacterial skin and skin structure infections (ABSSSI) trials, recent recommendations suggest a primary endpoint of reduction in skin lesion area. Objectives were: evaluate ABSSSI lesion area measurement reliability, evaluate impact of various lesion area definitions on treatment effect size, and explore relationships between lesion area and pain...
September 2016: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/27479071/proteomic-and-transcriptomic-analyses-of-swine-pathogen-erysipelothrix-rhusiopathiae-reveal-virulence-repertoire
#20
Yufeng Li, Yao Zou, Yuting Xia, Juan Bai, Xianwei Wang, Ping Jiang
E. rhusiopathiae is the causative agent of erysipelas in animals and erysipeloid in humans, but its pathogenicity is poorly understood. To identify virulence factors associated with E. rhusiopathiae and screen engineered vaccine candidates, we used proteomics and transcriptomics to compare the highly virulent strain HX130709 with an isogenic avirulent derivative, HX130709a. 1,299 proteins and 1,673 transcribed genes were identified and 1,292 of the proteins could be associated with genes. In a comparison between HX130907 and HX130709a, 168 proteins and 475 genes exhibited differences in regulation level...
2016: PloS One
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