Ghazaleh Mohammadalinejad, Babak Afsharipour, Alex Yacyshyn, Jennifer Duchcherer, Jack Bashuk, Erin Bennett, Gregory E P Pearcey, Francesco Negro, Katharina A Quinlan, David J Bennett, Monica A Gorassini
Motoneuron properties and their firing patterns undergo significant changes throughout development and in response to neuromodulators such as serotonin. Here, we examined the age-related development of self-sustained firing and general excitability of tibialis anterior motoneurons in a young development (7-17 years), young adult (18-28 years) and adult (32-53 years) group, as well as in a separate group of participants taking selective serotonin reuptake inhibitors (SSRIs, aged 11-28 years)...
March 30, 2024: Journal of Physiology