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Oral Capillary hemangioma

Stephany Vasco Ferreira, Flávia Caló Aquino Xavier, Maria da Conceição Andrade de Freitas, Fábio Daumas Nunes, Clarissa Araújo Gurgel, Maria Cristina Teixeira Cangussu, Manoela Domingues Martins, Valéria Souza Freitas, Jean Nunes Dos Santos
In view of the similarity of clinicopathological features between reactive lesions of the oral cavity, the objective of the present study was to investigate the density of MCs (mast cells) and microvessels in a series of these lesions. Thirty-seven cases of reactive lesions including fibrous hyperplasia (FH, n=10), inflammatory fibrous hyperplasia (IFH, n=10), peripheral giant cell lesion (PGCL, n=10) and lobular capillary hemangioma (LCH, n=7) were investigated using immunohistochemistry for mast cell tryptase and CD34...
September 2016: Pathology, Research and Practice
Marshall W Meeks, Umar M Kamal, Muhammad B Hammami, Jason R Taylor, M Louay Omran, Yongxin Chen, Jin-Ping Lai
Pyogenic granuloma (PG), more accurately known as lobular capillary hemangioma, is a benign vascular tumor that usually occurs in the skin or oral mucosa. This lesion is rarely reported in the gastrointestinal tract but is known to bleed if not resected. We herein describe a case series with the clinical, endoscopic, and histologic findings of four cases of gastrointestinal PG at our institution. In addition, we provide a review of the literature and summation of all reported cases of PG specific to the gastrointestinal tract...
2016: Case Reports in Gastrointestinal Medicine
Vinay Marla, Ashish Shrestha, Khushboo Goel, Sajeev Shrestha
Background. Pyogenic granuloma is a reactive tumor-like lesion commonly affecting the oral cavity. These lesions usually appear as localized solitary nodule with a sessile or pedunculated base and colour varying from red, purplish, or pink, depending on the vascularity of the lesion. Pyogenic granuloma shows predilection for gingiva and is usually slow growing, but at times it shows rapid growth. The natural course of this lesion can be categorized into three distinct phases, namely, (i) cellular phase, (ii) capillary phase/vascular phase, and (iii) involutionary phase...
2016: Case Reports in Dentistry
Vishal Vohra, Pulkit Gupta, Praveen K Malik, Ashok Pathak
Capillary hemangioma is one the most common tumors of eyelid and orbit reported in pediatric age group. Oral propranolol therapy is latest addition to the armamentarium of treatment options available to ophthalmologists in treating capillary hemangiomas. We report the successful response to propranolol therapy to a 5-year-old child with capillary hemangioma involving lids, orbit, and the paranasal sinuses. A long-term follow-up is necessary for the prognostic efficacy of the therapy.
September 2015: Oman Journal of Ophthalmology
Gérard Lorette, Dominique Goga, Anne Le Touze, Annabel Maruani, Denis Herbreteau
Hemangiomas are benign tumors that occur after a few days of life. The capillary malformations are isolated or constitute part of a complex angiomatosis. Venous malformations are low flow malformations with a blue color. They are of different types. The arteriovenous malformations are high flow lesions. They are difficult to treat. Lymphatic malformations are micro- or macrocystic. MRI is the gold standard for explorations. Some patients undergo maxillofacial surgical procedures and interventional radiology techniques for venous malformations, macrocystic lymphatic malformations, arteriovenous malformations...
February 2016: La Presse Médicale
Veena Raj Vasantha Kumari, Chitra Girija Vallabhan, Seema Geetha, Manoj S Nair, Tharun Varghese Jacob
Capillary Haemangioma is a benign vascular tumour characterized by proliferation of blood vessels that are primarily reported to be a developmental hamartomatous lesion of infancy and childhood. Pyogenic granuloma is a non-neoplastic benign lesion found in the oral cavity having a striking predilection for occurrence in the gingiva. The present case report is an atypical presentation of capillary haemangioma on gingiva which is considered to be extremely rare. The lesion in this case was clinically diagnosed as pyogenic granuloma but histopathologically as capillary haemangioma...
October 2015: Journal of Clinical and Diagnostic Research: JCDR
Shun-Ichi Misawa, Hiroto Sakamoto, Akira Kurogochi, Yasushi Kirii, Shinichiro Nakamura, Tomoko Misawa, Suguru Yoneda, Mari Hirano, Osamu Owa, Hiroyuki Takagi, Hiroyoshi Ota
BACKGROUND: Pyogenic granuloma (PG) is a polypoid lobular capillary hemangioma rarely observed in the gastrointestinal tract. Only a few cases in the small bowel have been described in the literature. CASE PRESENTATION: A 58-year-old man had been suffering from general fatigue and severe anemia. Esophagogastroduodenoscopy and colonoscopy did not reveal any significant bleeding. Abdominal computer tomography revealed a hypervascular tumor in the small intestine. Oral double-balloon endoscopy (DBE) detected a polypoid lesion (2 cm in diameter) in the jejunum...
2015: BMC Gastroenterology
Toyoyuki Hanazawa, Shuji Yonekura, Hiroko Nakamura, Akira Fujikawa, Yoshitaka Okamoto
Lobular capillary hemangiomas (LCHs), also known as pyogenic granulomas, are benign, rapidly growing hemorrhagic lesions that usually develop in the oral or nasal cavities. In adults, LCHs occur in <5% of all pregnant women. A 30-year-old woman presented with a 4-month history of right-sided nasal obstruction and recurrent epistaxis 2 months post-partum. A fragile, pink-red lobulated tumor existed in the anterior portion of the right inferior turbinate; the biopsy revealed a LCH. Although the patient declined surgery using an external approach, treatment with systemic corticosteroids combined with antibiotics resulted in tumor regression and an endoscopic en bloc resection was possible...
April 2016: Auris, Nasus, Larynx
Hirotaka Tanabe, Kazuhiro Sahashi, Tomoki Kitano, Yasushi Tomita, Akiko M Saito, Hiroshi Hirose
Oral propranolol hydrochloride has been proven effective in treating infantile hemangiomas, and its potential efficacy in choroidal hemangiomas has been suggested. A 57-year-old woman with a juxtapapillary capillary hemangioma was treated with oral propranolol at Nagoya Medical Center in Japan in 2012. Although the condition of this patient partially improved, oral propranolol did not appear to have a critical therapeutic effect. To the authors' knowledge, this is the first pilot study to describe a case in which oral propranolol was used as a therapeutic approach for a retinal hemangioma...
March 2015: Ophthalmic Surgery, Lasers & Imaging Retina
Naoyuki Matsumoto, Motomi Tsuchiya, Shouta Nomoto, Yasuyoshi Matsue, Yohichi Nishikawa, Tsuyoshi Takamura, Hidero Oki, Kazuo Komiyama
Capillary hemangioma (capillary lobular hemangioma) and cavernous hemangioma (venous malformation) are relatively common oral tumors/malformations and are characterized by increased numbers of normal and abnormal blood vessels. However, the causes of these lesions are not well understood. CD105 (endoglin) is predominantly expressed in proliferating blood endothelial cells (ECs). We analyzed expressions of CD105, CD34, von Willebrand factor, Ki-67, cyclooxygenase-2 (COX-2), and vascular endothelial growth factor (VEGF)-A in 31 capillary hemangiomas and 34 cavernous hemangiomas...
March 2015: Journal of Oral Science
Lata Goyal, Vivek Kumar Sharma, N D Gupta, Pankaj Bansal
Lack of striking clinical presentation makes the diagnosis of vascular lesions a difficult task. There lies a great probability that a case of capillary hemangioma at a rare location like the palate in a pregnant female might be misdiagnosed. Definitive diagnosis can only be made after thorough clinical and histopathological examination. Additional care needs to be exercised in a pregnant female while treating any tumor-like growth, including maintenance of diet and oral hygiene. We present one such case of capillary hemangioma of the palate in a pregnant female, along with treatment considerations...
October 2014: Journal of the Michigan Dental Association
Reza Fekrazad, Katayoun Am Kalhori, Nasim Chiniforush
Vascular lesions rise from abnormalities in blood vessels or endothelial proliferation. Capillary hemangiomas are formed by small capillaries surrounded by a layer of endothelial cells in a connective tissue stroma. Various treatments are used for these conditions like excisional surgery, sclerotherapy, and recently laser irradiation. In this case study, we report successful treatment of intraoral capillary hemangioma by gallium/aluminum/arsenide (GaAlAs) laser. A 29 year old woman with a red lesion on the upper side of the right maxillary premolar was referred to private dental office...
2013: Journal of Lasers in Medical Sciences
Ritu Dahiya, Abhinav Kathuria
Pyogenic granuloma is a tumor-like proliferation to a non-specific infection. The tumor-like growth is considered to be non-neoplastic in nature and presents in various clinical and histological forms in the oral cavity. Hemangiomas are benign vascular anomalies characterized by benign proliferation of blood vessels. The aim of this article is to drive attention toward the uncommon location of capillary hemangioma on the palate. In spite of their benign nature, intraoral capillary hemangiomas are always clinically important to be diagnosed well in time and suitably managed...
September 2014: Journal of Indian Society of Periodontology
C Gelmetti, R Cavalli
Infantile hemangiomas (IHs) are the most common tumors in infancy. Their typical natural history is characterized by an early rapid growth in the first months of life and by a slow spontaneous involution in the first years of life. Even though spontaneous regression of IHs could suggest therapeutic abstention, systemic treatment is the therapy of choice in many patients in which these situations occur: 1) rapid growth of IHs; 2) location of IHs in aesthetically critic areas; 3) recurrent hemorrhages, ulcerations or infections of IHs; 3) IHs interfering with important physiological functions (breathing, feeding, vision, hearing, etc...
December 2014: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
Alberto Barasoain-Millán, Francisco Javier Rodriguez-Contreras, Julio Guerrero-Fernandez, Maria Beato Merino, Isabel Gonzalez-Casado
Pyogenic granuloma, also named lobular capillary hemangioma, is a common proliferative vascular lesion known as a benign condition despite its rapid growth. It may appear in any cutaneous or mucosal surface but is usually restricted to the oral cavity. It is characterized by a friable mulberry-like lesion that can be sessile or pedunculated. Bleeding is usually its first clinical manifestation. Locations on respiratory, digestive and genital tracts are uncommon and sporadic. We describe the occurrence of an intravaginal pyogenic granuloma in a peripubertal girl with recurrent vaginal bleeding...
March 2015: Journal of Pediatric Endocrinology & Metabolism: JPEM
Azusa Kikuchi, Tomohisa Sujino, Minoru Yamaoka, Kazuaki Yoneno, Hideki Ohgo, Makoto Takagi, Shingo Morioka, Eiji Hirooka, Keiji Yamamoto, Nozomi Shinozuka, Taku Honma, Hidekazu Kayano, Hidetomo Nakamoto, Hiroyuki Imaeda
A pyogenic granuloma (PG) is a capillary hemangioma that usually occurs on the skin or in the oral cavity; it is rarely observed in the gastrointestinal tract. We herein describe a case of a 86-year-old woman who presented with anemia. Esophagogastroduodenoscopy and colonoscopy did not reveal any significant bleeding focus, but capsule endoscopy revealed a bleeding focus in the small intestine. We performed double-balloon enteroscopy and identified a 7-mm-diameter, reddish, subpedunculated, hemispheric polyp with a smooth surface in the small intestine, approximately 100 cm from the ileocecal valve...
2014: Internal Medicine
Hongzhuo Liu, Michael B Yang, S Kevin Li, Jinsong Hao
PURPOSE: Our previous study demonstrated that topical ocular instillation can deliver effective concentrations of propranolol in the periocular tissues, and may be superior to oral propranolol in the treatment of periocular capillary hemangiomas. The objective of this study was to investigate the effects of dosing protocol on the distribution of propranolol in the periocular tissues and plasma after topical ocular instillation. METHODS: Each rabbit received propranolol 0...
May 2015: Current Eye Research
Ronald Natawidjaja, Ewen Wang
Infantile haemangiomas affect approximately 5% of the population and usually do not require treatment. However, complex cutaneous haemangiomas can cause disabling disfigurement, while haemangiomas in the brain, airway or gastrointestinal tract can cause life-threatening complications. Although children with infantile haemangiomas are often first brought to general practitioners and paediatricians by parents for care, they are thought of as a surgical problem and usually referred to specialty care. We present a case of an infant from a resource-poor setting in rural Indonesia with disfiguring facial haemangiomas, as well as a probable airway haemangioma causing stridor at rest...
2014: BMJ Case Reports
Young-Hoon Kang, June-Ho Byun, Mun-Jeong Choi, Jong-Sil Lee, Jung-Hui Jang, Young-Il Kim, Bong-Wook Park
INTRODUCTION: The development of various benign oral mucosal lesions associated with dental implants, such as pyogenic granuloma or peripheral giant cell granuloma, has been rarely reported. However, the occurrence of vascular diseases, such as hemangioma, related to dental implants has not been explored in the literature. In this study, we report a case of co-development of pyogenic granuloma and capillary hemangioma on the alveolar ridge associated with a dental implant in a patient undergoing antithrombotic therapy...
2014: Journal of Medical Case Reports
Roderic J Phillips, Zerina Lokmic, Catherine M Crock, Anthony Penington
AIM: To describe the clinical and histopathological characteristics of infantile haemangiomas that failed treatment with oral propranolol . DESIGN: This study is a case series from the vascular birthmarks clinic at Royal Children's Hospital, Melbourne. PATIENTS: The patients for this study were infants who commenced treatment with oral propranolol before 6 months of age and who were treated for at least 4 months without a satisfactory result...
August 2014: Journal of Paediatrics and Child Health
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