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https://www.readbyqxmd.com/read/29049986/new-diagnostic-criteria-of-polycystic-ovarian-morphology-for-adolescents-impact-on-prevalence-and-hormonal-profile
#1
Paulina M Merino, Claudio Villarroel, Cristián Jesam, Patricia López, Ethel Codner
BACKGROUND: The ultrasonographic criteria used to identify polycystic ovarian morphology (PCOM) during adolescence have changed over time. Recently, a Worldwide Pediatric Consensus (PedC) defined PCOM using stricter criteria than the previous recommendations of the Rotterdam Consensus (RC) and Androgen Excess-Polycystic Ovarian Syndrome Society (AES/PCOS) criteria. The aim of this study was to determine the prevalence of PCOM in healthy adolescents according to the 3 reported diagnostic criteria and compare the hormonal profile in females with and without PCOM based on the PedC criteria...
October 19, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28936194/the-siesta-habit-is-associated-with-a-decreased-risk-of-rupture-of-intracranial-aneurysms
#2
Huibin Kang, Xin Feng, Baorui Zhang, Erkang Guo, Luyao Wang, Zenghui Qian, Peng Liu, Xiaolong Wen, Wenjuan Xu, Youxiang Li, Chuhan Jiang, Zhongxue Wu, Hongbing Zhang, Aihua Liu
BACKGROUND: Previous studies have examined an association between the siesta habit and hypertension, as well as coronary heart disease. However, the relationship between a siesta and the risk of rupture of an intracranial aneurysm (IA) has not yet been established. We aimed to investigate the effects of a siesta on the risk of rupture of IAs. METHODS: We prospectively enrolled consecutive patients diagnosed with IAs at our hospital between January 2016 and December 2016...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28879505/recovery-of-oculomotor-nerve-palsy-after-endovascular-treatment-of-ruptured-posterior-communicating-artery-aneurysm
#3
Qing-Quan Zu, Xing-Long Liu, Bin Wang, Chun-Gao Zhou, Jin-Guo Xia, Lin-Bo Zhao, Hai-Bin Shi, Sheng Liu
PURPOSE: Oculomotor nerve palsy (ONP) may result from Posterior communicating artery (Pcom) aneurysms. Endovascular treatment of ruptured Pcom aneurysms generally is a safe procedure, but the effect of this therapy on ONP is incompletely elucidated. This retrospective study evaluates outcomes of ONP after endovascular treatment for ruptured Pcom aneurysm and with the intention to clarify predictors of recovery. METHODS: From May 2010 to October 2015, 210 patients with Pcom aneurysms underwent endovascular treatment at our institution...
September 6, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28875230/b-flow-sonography-for-evaluation-of-basal-cerebral-arteries-in-newborns
#4
M Groth, M Ernst, P Deindl, J Herrmann
The aim of the study was to evaluate the B‑flow sonography (BFS) to image the basal cerebral arteries in newborn infants. For this purpose 34 newborns, who underwent standardized ultrasound of the brain including BFS, color Doppler (CDS) and power Doppler (PDS) techniques were retrospectively assessed. Delineation of the anterior communicating (Acom), the posterior communicating (Pcom), the middle cerebral (M1 and M2 segments), the anterior cerebral (A1 and A2 segments), and the posterior cerebral artery (P1 and P2 segments) were visually scored...
September 5, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28854589/use-of-the-serum-anti-m%C3%A3-llerian-hormone-assay-as-a-surrogate-for-polycystic-ovarian-morphology-impact-on-diagnosis-and-phenotypic-classification-of-polycystic-ovary-syndrome
#5
Alice Fraissinet, Geoffroy Robin, Pascal Pigny, Tiphaine Lefebvre, Sophie Catteau-Jonard, Didier Dewailly
STUDY QUESTION: Does the use of the serum anti-Müllerian hormone (AMH) assay to replace or complement ultrasound (U/S) affect the diagnosis or phenotypic distribution of polycystic ovary syndrome (PCOS)? SUMMARY ANSWER: Combining U/S and the serum AMH assay to define polycystic ovarian morphology (PCOM) diagnoses PCOS (according to the Rotterdam classification) in more patients than definitions using one or the other of these indicators exclusively. WHAT IS KNOWN ALREADY: Since 2003, PCOM, as defined by U/S, is one of the three diagnostic criteria for PCOS...
August 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28854584/polycystic-ovarian-morphology-and-the-diagnosis-of-polycystic-ovary-syndrome-redefining-threshold-levels-for-follicle-count-and-serum-anti-m%C3%A3-llerian-hormone-using-cluster-analysis
#6
S Lie Fong, J S E Laven, A Duhamel, D Dewailly
STUDY QUESTION: Can cluster analysis be used to differentiate between normo-ovulatory women with normal ovaries and normo-ovulatory women with polycystic ovarian morphology (PCOM) in a non-subjective manner? SUMMARY ANSWER: Cluster analysis can be used to accurately and non-subjectively differentiate between normo-ovulatory women with normal ovaries and normo-ovulatory women with PCOM. WHAT IS KNOWN ALREADY: Currently, PCOM is diagnosed using a fixed threshold level, i...
August 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28736349/completion-of-the-circle-of-willis-varies-by-gender-age-and-indication-for-computed-tomography-angiography
#7
Orel A Zaninovich, Wyatt L Ramey, Christina M Walter, Travis M Dumont
OBJECTIVE: The circle of Willis (CoW) is the foremost anastomosis and blood distribution center of the brain. Its effectiveness depends on its completion and the size and patency of its vessels. Gender-related and age-related anatomic variations in the CoW may play an important role in the pathogenesis of cerebrovascular diseases. In this study, we analyzed computed tomography angiograms (CTAs) to assess for differences in CoW completion related to gender, age, and indication for CTA...
October 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28733169/implications-of-the-2014-androgen-excess-and-polycystic-ovary-syndrome-society-guidelines-on-polycystic-ovarian-morphology-for-polycystic-ovary-syndrome-diagnosis
#8
J P Christ, M N Gunning, B C J M Fauser
The Androgen Excess and Polycystic Ovary Syndrome Society (AEPCOS) has recommended an updated threshold for polycystic ovarian morphology (PCOM) of 25 follicles or more, 10 ml or more of ovarian volume, or both. We describe the effect of these guidelines on reproductive and metabolic characteristics in 404 women. These women were separated into four groups: group A: hyperandrogenism and oligo-amenorrhoea (n = 157); group B: hyperandrogenism or oligo-amenorrhoea and PCOM meeting AEPCOS 2014 criteria (n = 125); group C: hyperandrogenism or oligo-amenorrhoea and PCOM meeting Rotterdam 2003 but not AEPCOS 2014 criteria (n = 72); and group D: non-PCOS not meeting either criteria (n = 50)...
July 8, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28681949/age-stratified-thresholds-of-anti-m%C3%A3-llerian-hormone-improve-prediction-of-polycystic-ovary-syndrome-over-a-population-based-threshold
#9
Molly M Quinn, Chia-Ning Kao, Asima K Ahmad, Daniel J Haisenleder, Nanette Santoro, Esther Eisenberg, Richard S Legro, Marcelle I Cedars, Heather G Huddleston
OBJECTIVE: Due to its consistent elevation in polycystic ovary syndrome (PCOS) and correlation with polycystic ovarian morphology (PCOM), anti-Mullerian hormone (AMH) has been proposed as a marker of the syndrome. However, prior studies reporting thresholds of AMH for a PCOS diagnosis have been limited by small sample size, inappropriate controls, and heterogeneous AMH assays. We sought to evaluate the suitability of a standardized AMH assay as a biomarker of PCOS. DESIGN: Cross-sectional study at academic medical centres across the United States...
July 6, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28602923/successful-hybrid-neurovascular-surgery-for-a-ruptured-basilar-artery-dissecting-aneurysm-in-a-patient-with-jeopardized-collateral-circulation-associated-with-aortitis-syndrome
#10
Kazuaki Yamamoto, Takahisa Mori, Tsuyoshi Watanabe, Tomonori Iwata, Gakuji Gondo, Masahiko Tanaka, Satoshi Tanaka
BACKGROUND: Dissecting aneurysms of the basilar artery (BA) are rare lesions, and the management of them has been controversial and challenging. The treatment becomes much more difficult when the patient has a disorder such as aortitis syndrome, which makes cerebral arteries occluded and tortuous. We describe a case of a ruptured BA dissecting aneurysm associated with aortitis syndrome, successfully treated with hybrid neurovascular surgery. CASE DESCRIPTION: A 64-year-old woman with a medical history of aortitis syndrome developed a severe headache and was diagnosed with a subarachnoid hemorrhage from a BA dissecting aneurysm...
September 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28597496/elevated-anti-mullerian-hormone-in-lean-women-may-not-indicate-polycystic-ovarian-syndrome
#11
Rachel A Bradbury, Paul Lee, Howard C Smith
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a heterogeneous disorder with clinical features shared with functional hypogonadotrophic hypogonadism (FHH). AIM: To investigate the usefulness of an elevated (>40 pmol/L) anti-Mullerian hormone (AMH) in identifying PCOS and distinguishing PCOS from FHH. MATERIALS AND METHODS: 141 patients with an elevated AMH and body mass index either <20 kg/m(2) (lean) or >30 kg/m(2) (obese) were selected and three subgroups analysed - obese, lean, lean with suspected FHH...
October 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28543550/polycystic-ovary-morphology-is-associated-with-insulin-resistance-in-women-with-polycystic-ovary-syndrome
#12
So-Hyeon Hong, Yeon-Ah Sung, Young Sun Hong, Kyungah Jeong, Hyewon Chung, Hyejin Lee
BACKGROUND/OBJECTIVES: Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by chronic anovulation, hyperandrogenism, polycystic ovary morphology (PCOM) and metabolic disturbances including insulin resistance and type 2 diabetes mellitus. Although insulin resistance could be associated with PCOM, recent studies have shown controversial results. The aim of this study was to determine the relationship between PCOM and insulin resistance. SUBJECTS/METHODS: This was a cross-sectional clinical study...
October 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28505246/effects-of-long-term-exogenous-testosterone-administration-on-ovarian-morphology-determined-by-transvaginal-3d-ultrasound-in-female-to-male-transsexuals
#13
Mirte R Caanen, Nienke E Schouten, Esther A M Kuijper, Joukje van Rijswijk, Marleen H van den Berg, Eline van Dulmen-den Broeder, Annelies Overbeek, Flora E van Leeuwen, Mick van Trotsenburg, Cornelis B Lambalk
STUDY QUESTION: Does long-term exogenous testosterone administration result in polycystic ovarian morphology (PCOM), determined by (3D) transvaginal ultrasound (TVU) in female-to-male transsexuals (FtMs). SUMMARY ANSWER: Long-term exogenous testosterone administration in FtMs does not result in PCOM determined by (3D) TVU. WHAT IS KNOWN ALREADY: The role of androgens in the pathophysiology of polycystic ovary syndrome (PCOS) is still unclear...
July 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28454499/phenotypic-variation-in-anti-mullerian-hormone-amh-production-per-follicle-in-women-with-polycystic-ovary-syndrome-pcos-and-isolated-polycystic-ovarian-morphology-pcom-an-observational-cross-sectional-study
#14
Priya Bhide, Abhijit Kulkarni, Merve Dilgil, Puja Dhir, Amit Shah, Anil Gudi, Roy Homburg
This observational study compares the ratio of serum anti-Mullerian hormone (AMH) to the total antral follicle count (AFC) (as a marker of AMH production per follicle) in the various phenotypes of women with polycystic ovary syndrome (PCOS) and isolated polycystic ovarian morphology (PCOM). Two hundred and sixty-two women were recruited. Women with PCOS were divided into four phenotypes based on the diagnostic inclusion criteria of oligo-anovulation (OA), hyperandrogenism (HA) and polycystic ovarian morphology (PCOM)...
October 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28381699/relationship-between-serum-anti-mullerian-hormone-and-clinical-parameters-in-polycystic-ovary-syndrome
#15
Toshiya Matsuzaki, Munkhsaikhan Munkhzaya, Takeshi Iwasa, Altankhuu Tungalagsuvd, Kiyohito Yano, Yiliyasi Mayila, Rie Yanagihara, Takako Tokui, Takeshi Kato, Akira Kuwahara, Sumika Matsui, Minoru Irahara
Polycystic ovary syndrome (PCOS) is an ovulatory disorder that affects 6-10% of women of reproductive age. Serum AMH level may be an additional factor, or surrogate of PCOM, in the diagnostic criteria of PCOS. We evaluated the correlations between the serum AMH level and various endocrine and metabolic features in PCOS using the latest fully automated assay. Serum AMH level was compared between 114 PCOS patient (PCOS group) and 95 normal menstrual cycle women (Control group). Correlations between serum AMH level and various endocrine and metabolic factors were analysed in PCOS group...
April 1, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28335839/apolipoprotein-l1-variants%C3%A2-and-blood-pressure-traits-in%C3%A2-african-americans
#16
Girish N Nadkarni, Geneviève Galarneau, Stephen B Ellis, Rajiv Nadukuru, Jinglan Zhang, Stuart A Scott, Claudia Schurmann, Rongling Li, Laura J Rasmussen-Torvik, Abel N Kho, M Geoffrey Hayes, Jennifer A Pacheco, Teri A Manolio, Rex L Chisholm, Dan M Roden, Joshua C Denny, Eimear E Kenny, Erwin P Bottinger
BACKGROUND: African Americans (AA) are disproportionately affected by hypertension-related health disparities. Apolipoprotein L1 (APOL1) risk variants are associated with kidney disease in hypertensive AAs. OBJECTIVES: This study assessed the APOL1 risk alleles' association with blood pressure traits in AAs. METHODS: The discovery cohort included 5,204 AA participants from Mount Sinai's BioMe biobank. Replication cohorts included additional BioMe (n = 1,623), Vanderbilt BioVU (n = 1,809), and Northwestern NUgene (n = 567) AA biobank participants...
March 28, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28303209/mixed-aneurysm-a-new-proposed-nomenclature-for-a-rare-condition
#17
Cassiano U Crusius, Paulo Henrique P de Aguiar, Marcelo U Crusius
BACKGROUND: Mixed intracranial aneurysms are vascular lesions appearing in the ruptured saccular aneurysms whose blood is contained by perivascular tissues forming another cavity called pseudoaneurysm. All cases until now have been reported in the literature with subarachnoid hemorrhage. CASE DESCRIPTION: A 65-year-old woman presented with multiple brain aneurysms with no history of subarachnoid hemorrhage. Endovascular treatment was chosen for left-sided aneurysms [lateral carotid wall (LCW) and posterior communicating (PCom)]...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28238423/a-computational-algorithm-for-classifying-step-and-spin-turns-using-pelvic-center-of-mass-trajectory-and-foot-position
#18
Pawel R Golyski, Brad D Hendershot
Transient changes in direction during ambulation are typically performed using a step (outside) or spin (inside) turning strategy, often identified through subjective and time-consuming visual rating. Here, we present a computational, marker-based classification method utilizing pelvic center of mass (pCOM) trajectory and time-distance parameters to quantitatively identify turning strategy. Relative to visual evaluation by three independent raters, sensitivity, specificity, and overall accuracy of the pCOM-based classification method were evaluated for 90-degree turns performed by 3 separate populations (5 uninjured controls, 5 persons with transtibial amputation, and 5 persons with transfemoral amputation); each completed turns using two distinct cueing paradigms (i...
January 30, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28198523/diversity-among-posterior-thalamoperforating-branches-originated-from-p1-segment-systematic-review
#19
Cezary Grochowski, Ryszard Maciejewski
BACKGROUND: The P1 segment of the posterior cerebral artery (PCA) begins at the termination of the basilar artery and ends at the origin of posterior communicating artery (PCoM), within the interpeduncular cistern. Perforating branches arising from this segment are called posterior thalamoperforating arteries and the main and biggest artery among those is called thalamoperforating artery (TPA). Perforating branches are a crucial component of cerebrovascular system supplying the posterior part of the thalamus, subthalamus, hypothalamus, substantia nigra, perforated substance, posterior part of internal capsule and the nucleus of III and IV cranial nerve...
February 15, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28090185/characteristics-and-outcomes-of-patients-with-anterior-circulation-intracranial-aneurysm-managed-with-clipping-in-hospital-sungai-buloh
#20
Ailani Ab Ghani, Saiful Azli Mat Nayan, Regunath Kandasamy, Azmin Kas Rosman, Abdul Rahman Izani Ghani
INTRODUCTION: The annual incidence of intracranial aneurysm in Malaysia is estimated to be 1.1-1.7 per 100,000 population based on a study done conducted in 1988. Since then, little epidemiological research has been conducted in Malaysia, and the real incidence is therefore probably unreported despite advancements in the diagnosis and treatment of this disorder. Intracranial aneurysm may be treated by microsurgical clipping or embolisation depending on its location and the surgeon's preference...
November 2016: Malaysian Journal of Medical Sciences: MJMS
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