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https://www.readbyqxmd.com/read/29662281/role-of-amh-as-diagnostic-tool-for-polycystic-ovarian-syndrome
#1
Upma Saxena, Manisha Ramani, Pushpa Singh
Background: To evaluate role of AMH as a diagnostic tool for PCOS. Methods: This was a prospective case-control study on women attending Gynae OPD of Dr RML Hospital, New Delhi, from 1 November 2015 to 31 March 2017. Study comprised of 45 women with PCOS, diagnosed using Rotterdam criteria and 45 women as controls. Clinical history included oligomenorrhea, hirsutism, examination included BMI, Ferriman-Gallwey score, investigations included blood for FSH, LH, estradiol, TSH, prolactin, total testosterone, AMH level and pelvic USG which was done for all women...
April 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29656154/acute-recanalization-of-a-partially-thrombosed-large-intracranial-aneurysm
#2
E Atallah, E Valle-Giler, T Elarjani, N Chalouhi, S Tjoumakaris, R H Rosenwasser, N Herial, M R Gooch, H Zarzour, P Jabbour
BACKGROUND: Thrombosed large intracranial aneurysms(TLIAs) are not continuously contemplated as stable lesions. Completely occluded large IAs' spontaneous recanalization has been previously described. CASE DESCRIPTION: We report the case of a middle-aged patient presenting with agitation, acute headache, visual field defects and left hemiparesis. A large thrombosed Posterior Communicating (PCom) artery aneurysm was identified with an infarct at the same arterial territory on neuroimaging studies...
April 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29589286/genetic-and-environmental-contributions-to-variation-in-the-posterior-communicating-collaterals-of-the-circle-of-willis
#3
James E Faber, Hua Zhang, Wojciech Rzechorzek, Kathy Z Dai, Benjamin T Summers, Cooper Blazek, Samuel J Hedges
Variation in blood flow mediated by the posterior communicating collateral arteries (PComs) contributes to variation in the severity of tissue injury in obstructive disease. Evidence in animals and humans indicates that differences in the extent of PComs, i.e., their anatomic lumen diameter and whether they are present bilaterally, unilaterally, or absent, are a major factor. These differences arise during development since they are present at birth. However, the causal mechanisms are unknown. We used angiography after maximal dilation to examine involvement of genetic, environmental, and stochastic factors...
March 27, 2018: Translational Stroke Research
https://www.readbyqxmd.com/read/29530697/strictly-limited-orbital-pain-as-a-sentinel-headache-of-sah-a-case-report
#4
Shigeomi Yokoya, Akihiko Hino, Yukihiro Goto, Youichi Hashimoto, Hideki Oka
BACKGROUND: The headache preceding an intracranial aneurysm (AN) rupture is called a sentinel headache (SH), and it is characterized by a sudden, intense, and persistent headache. As subarachnoid hemorrhage (SAH) often develops within several weeks of SH, its rapid diagnosis and treatment can improve the prognosis. CASE DESCRIPTION: A 52-year-old woman with migraine in her medical history visited the outpatient clinic due to left orbital pain. There was no neurological deficit...
March 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29520753/the-partners-for-change-outcome-management-system-a-both-and-system-for-collaborative-practice
#5
Jacqueline A Sparks, Barry L Duncan
Systematic client feedback (SCF) is increasingly employed in mental health services worldwide. While research supports its efficacy over treatment as usual, clinicians, especially those who highly value relational practices, may be concerned that routine data collection detracts from clinical process. This article describes one SCF system, the Partners for Change Outcome Management System (PCOMS, 2015), along a normative (standardized measurement) to communicative (conversational) continuum, highlighting PCOMS' origins in everyday clinical practice...
March 9, 2018: Family Process
https://www.readbyqxmd.com/read/29510894/a-new-type-of-hyperplastic-anterior-choroidal-artery
#6
Kazuma Doi, Takamasa Mizuno, Yoshinori Shigematsu, Osamu Kobayashi, Tatsuya Takezaki, Daisuke Muta, Toru Nishi
Hyperplastic anomaly of the anterior choroidal artery (hyperplastic AchA) and posterior communicating artery of duplicate origin (duplicated Pcom) are rare vessel anomalies. With some literature review, we here report three cases of hyperplastic AchA, one of which was considered a new type of hyperplastic AchA. This case was not categorized into Takahashi classification.
March 3, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29462707/the-diagnostic-value-of-anti-mullerian-hormone-in-early-post-menarche-adolescent-girls-with-polycystic-ovarian-syndrome
#7
Pınar Kocaay, Zeynep Siklar, Sema Buyukfirat, Merih Berberoglu
STUDY OBJECTIVE: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterized by hyperandrogenism and chronic anovulation, which affects 5-10% of reproductive age females. Diagnosis of adult patients with PCOS is made easily with clinical and laboratory methods and the antimullerian hormone (AMH) level are accepted as a good indicator. However, there is still no complete consensus on the diagnosis of PCOS in adolescents. DESIGN: and Settings: Prospective cohort study, December 2013 to November 2014 PARTICIPANTS: The study was conducted on adolescent girls with oligomenorrhea, with at least two years since menarche...
February 17, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29457875/variations-of-the-circle-of-willis-at-the-end-of-the-human-embryonic-period
#8
Kana Furuichi, Aoi Ishikawa, Chigako Uwabe, Haruyuki Makishima, Shigehito Yamada, Tetsuya Takakuwa
Variations of the circle of Willis (CW) influence blood supply to the brain and adjacent structures in adults. We examined the formation of the CW in 20 human embryo samples at the end of the embryonic period using 3-D reconstructions of serial histological sections. The CW was closed in all samples, and did not form in a single plane, but was composed of multiple stair-like planes. The artery acutely curved at the caudal part of the CW, namely at the inlet of the basilar artery and bifurcation of the P1 segment of the posterior cerebral artery (PCA), reflecting flexure of the mesencephalon and diencephalon at this stage...
February 19, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29404254/contralateral-minimum-anterior-and-posterior-combined-petrosal-approach-for-retrochiasmatic-craniopharyngiomas-an-alternative-technique
#9
Sachin Ranganatha Goudihalli, Hiroki Morisako, Wimba Prastarana, Takeo Goto, Hiroki Ohata, Kenji Ohata
Retrochiasmatic craniopharyngiomas (RC) are a challenge for the neurosurgeon to treat surgically, restrained by their location in the interpeduncular fossa, surrounded by vital neurovascular structures, narrow corridor and poor visibility. Many approaches are possible and elucidated in the literature, which the surgeon chooses, based on multiple factors, such as the size of tumor, calcification, laterality, preoperative neurological deficits and the endocrine function status, recurrence, postradiotherapy status, or significant superior and/or posterior extension...
February 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29394920/occipital-lobe-infarction-a-rare-presentation-of-bilateral-giant-cavernous-carotid-aneurysms-a-case-report
#10
Kavin Vanikieti, Anuchit Poonyathalang, Panitha Jindahra, Piyaphon Cheecharoen, Wimonwan Chokthaweesak
BACKGROUND: Cavernous carotid aneurysm (CCA) represents 2-9% of all intracranial aneurysms and 15% of internal carotid artery (ICA) aneurysms; additionally, giant aneurysms are those aneurysms that are > 25 mm in size. Bilateral CCAs account for 11-29% of patients and are commonly associated with structural weaknesses in the ICA wall, secondary to systemic hypertension. CCAs are considered benign lesions, given the low risk for developing major neurologic morbidities (i.e., subarachnoid hemorrhage, cerebral infarction, or carotid cavernous fistula)...
February 2, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29370410/gut-microbial-diversity-in-women-with-polycystic-ovary-syndrome-correlates-with-hyperandrogenism
#11
Pedro J Torres, Martyna Siakowska, Beata Banaszewska, Leszek Pawelczyk, Antoni J Duleba, Scott T Kelley, Varykina G Thackray
Context: A majority of women with polycystic ovary syndrome (PCOS) have metabolic abnormalities that result in an increased risk of developing type 2 diabetes and heart disease. Correlative studies have shown an association between changes in the gut microbiome and metabolic disorders. Two recent studies reported a decrease in alpha diversity of the gut microbiome in women with PCOS compared with healthy women. Objective: We investigated whether changes in the gut microbiome correlated with specific clinical parameters in women with PCOS compared to healthy women...
January 23, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29340861/investigating-the-composition-characteristics-of-dissolved-and-particulate-colloidal-organic-matter-in-effluent-dominated-stream-using-fluorescence-spectroscopy-combined-with-multivariable-analysis
#12
Min-Da Yu, Xiao-Song He, Bei-Dou Xi, Ru-Tai Gao, Xian-Wei Zhao, Hui Zhang, Cai-Hong Huang, Wenbing Tan
Fluorescence excitation-emission matrix (EEM) spectroscopy combined with principal component analysis (PCA) and parallel factor analysis (PARAFAC) were used to investigate the compositional characteristics of dissolved and particulate/colloidal organic matter and its correlations with nitrogen, phosphorus, and heavy metals in an effluent-dominated stream, Northern China. The results showed that dissolved organic matter (DOM) was comprised of fulvic-like, humic-like, and protein-like components in the water samples, and fulvic-like substances were the main fraction of DOM among them...
January 17, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29289990/prevalence-clinical-characteristics-and-reproductive-outcomes-of-polycystic-ovary-syndrome-in-older-women-referred-for-tertiary-fertility-care
#13
Samer Tannus, Justin Tan, Weon-Young Son, Michael-Haim Dahan
OBJECTIVE: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women. The clinical symptoms of PCOS vary with female age, as older women tend to have lower hyperandrogenic symptoms and many regain regular cycles. In this study, we aimed to estimate the prevalence of PCOS among older women referred for fertility care, describe their clinical characteristics, and compare their reproductive outcomes to those of matched control group. METHODS: A retrospective study conducted at a single reproductive center...
April 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29213291/apolipoprotein-e-polymorphism-and-the-risk-of-aneurysmal-subarachnoid-hemorrhage-in-a-south-indian-population
#14
Arati Suvatha, Sibin Madathan Kandi, Dhananjaya Ishwara Bhat, Narasinga Rao, Vikas Vazhayil, Chetan Ghati Kasturirangan
Background: The rupture of a brain aneurysm causes bleeding in the subarachnoid space. This is known as aneurysmal subarachnoid hemorrhage (aSAH). We evaluated the association of apolipoprotein E ( APOE ) polymorphism and the risk of aSAH in a South Indian population. Methods: The study was performed on 200 subjects with aSAH and 253 healthy control subjects. Blood samples (5 ml) were used to isolate DNA and genotyping was performed for rs7412 and rs429358 using a Taqman allelic discrimination assay...
2017: Cellular & Molecular Biology Letters
https://www.readbyqxmd.com/read/29194016/assessment-of-occupational-exposure-to-asbestos-fibers-contribution-of-analytical-transmission-electron-microscopy-analysis-and-comparison-with-phase-contrast-microscopy
#15
Céline Eypert-Blaison, Anita Romero-Hariot, Frédéric Clerc, Raymond Vincent
From November 2009 to October 2010, the French general directorate for labor organized a large field-study using analytical transmission electron microscopy (ATEM) to characterize occupational exposure to asbestos fibers during work on asbestos containing materials (ACM). The primary objective of this study was to establish a method and to validate the feasibility of using ATEM for the analysis of airborne asbestos of individual filters sampled in various occupational environments. For each sampling event, ATEM data were compared to those obtained by phase-contrast optical microscopy (PCOM), the WHO-recommended reference technique...
March 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29190387/chronic-hyperandrogenemia-in-the-presence-and-absence-of-a-western-style-diet-impairs-ovarian-and-uterine-structure-function-in-young-adult-rhesus-monkeys
#16
Cecily V Bishop, Emily C Mishler, Diana L Takahashi, Taylor E Reiter, Kise R Bond, Cadence A True, Ov D Slayden, Richard L Stouffer
STUDY QUESTION: Does chronic hyperandrogenemia beginning at menarche, in the absence and presence of a western-style diet (WSD), alter ovarian and uterine structure-function in young adult rhesus monkeys? SUMMARY ANSWER: Phenotypic alterations in ovarian and uterine structure/function were induced by exogenous testosterone (T), and compounded in the presence of a WSD (T+WSD). WHAT IS KNOWN ALREADY: Hyperandrogenemia is a well-established component of PCOS and is observed in adolescent girls, indicating a potential pubertal onset of disease symptoms...
January 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29184806/polycystic-ovary-syndrome-in-adolescence-diagnostic-and-therapeutic-strategies
#17
REVIEW
Manmohan K Kamboj, Andrea E Bonny
Controversy continues about the underlying etiopathogenesis, diagnostic criteria, and recommendations for polycystic ovary syndrome (PCOS) in adolescents. Recent literature has recognized these deficiencies and evidence based expert recommendations have become more available. The purpose of this chapter is to offer primary care providers a practical understanding and approach to the diagnosis and treatment of PCOS in adolescents. Although the presence of polycystic ovary morphology (PCOM) is included as a key diagnostic criterion of PCOS in adults, it is currently not recommended for the diagnosis in adolescents...
October 2017: Translational pediatrics
https://www.readbyqxmd.com/read/29172287/polycystic-ovarian-morphology-may-be-a-positive-prognostic-factor-in-patients-with-endometrial-cancer-who-achieved-complete-remission-after-fertility-sparing-therapy-with-progestin
#18
Yamato Fukui, Ayumi Taguchi, Katsuyuki Adachi, Marie Sato, Akira Kawata, Michihiro Tanikawa, Kenbun Sone, Mayuyo Mori, Kazunori Nagasaka, Yoko Matsumoto, Takahide Arimoto, Katsutoshi Oda, Yutaka Osuga, Tomoyuki Fujii
Background: The most studied fertility-sparing therapy for endometrial cancer (EC) is oral progestin therapy. However, complete remission (CR) rate after progestin therapy is not enough ranging from 60 to 80 %, with high recurrence rate. Clinical features that predict treatment efficacy and recurrence after progestin therapy have not yet been revealed in detail. The aim of this study was to investigate prognostic factors in patients with EC who achieved CR after medroxyprogesterone acetate (MPA) therapy. Methods: We retrospectively reviewed 35 EC patients treated with MPA at our institution between 2000 and 2016...
November 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29118804/hybrid-retrograde-antegrade-recanalization-of-acute-basilar-artery-occlusion
#19
James D Rossen, Edgar A Samaniego, Mishelle Paullus, Santiago Ortega-Gutierrez
Acute basilar artery (BA) occlusion has a very poor prognosis. Recanalization can be challenged by bilateral vertebral artery (VA) occlusions, arterial dissection, or advanced atherosclerotic disease. We describe a case in whom the BA was accessed and recanalized through a retrograde-antegrade approach from the anterior circulation using a large posterior communicating artery (PCOM). Once the BA had been crossed retrogradely through the PCOM, another microcatheter was advanced antegradely through the VA into the BA and right posterior cerebral artery using the "buddy-wire" technique...
October 2017: Interventional Neurology
https://www.readbyqxmd.com/read/29114304/thrombosed-giant-true-posterior-communicating-artery-aneurysm-treated-by-trapping-and-thrombectomy
#20
Yuichi Mochizuki, Akitsugu Kawashima, Koji Yamaguch, Yoshikazu Okada
Giant "true" posterior communicating artery (PCOM) aneurysms are rare and the best surgical treatment for them is unclear. We present a case of 85-year-old woman with this type of lesion, 35 mm in diameter, successfully treated by trapping and thrombectomy via pterional approach without complications. There were no perforating arteries originating from the aneurysmal wall. The patient had an uneventful postoperative course. The key for successful treatment for such lesions is preservation of perforators, as trapping may result in ischemic complications...
October 2017: Asian Journal of Neurosurgery
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