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https://www.readbyqxmd.com/read/28429602/endoscopic-treatment-of-symptomatic-fibroids-at-reproductive-age-and-beyond
#1
Khulkar Abdusattarova, Liselotte Mettler, Ibrahim Alkatout, Astrid Dempfle
OBJECTIVES: To evaluate the feasibility of endoscopic treatment of symptomatic uterine fibroids based on patient and fibroid characteristics in reproductive, pre-menopausal and post-menopausal women. MATERIAL AND METHODS: The medical records of women with symptomatic uterine fibroids who underwent surgical procedures from 2010 to 2015 were retrospectively reviewed. RESULTS: A total of 819 patients, of which 710 (86.6%) underwent endoscopic procedures...
April 21, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28422387/should-we-be-putting-our-scalpel-down-is-hifu-the-answer-to-fertility-sparing-fibroid-treatment
#2
Nicola Tempest, Dharani Hapangama
Despite HIFU being a fertility sparing, outpatient procedure reported to be safe and effective in treating patients with fibroids for 15 years (Wang et al. Zhonghua Chao Sheng Ying Xiang Xue Za Zhi 2002; 11:161-63); approved by the FDA in America in 2004; and seen to have similar cost-effectiveness as all other uterine preserving treatments; it is currently only available in two private treatment centers and on a case by case basis on the NHS in the UK and not consistently covered by any major US insurance company...
April 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28421665/evaluation-of-hifu-ablation-for-uterine-fibroids-an-ideal-prospective-exploration-study
#3
Jinyun Chen, Youping Li, Zhibiao Wang, Peter McCulloch, Liang Hu, Wenzhi Chen, Guanjian Liu, Jing Li, Jinghe Lang
OBJECTIVE: To evaluate the clinical outcomes of High intensity focused ultrasound (HIFU) and surgery in treating uterine fibroids, and prepare for a definitive randomised trial. DESIGN: Prospective multicentre patient choice cohort study (IDEAL Exploratory study) of HIFU, myomectomy or hysterectomy for treating symptomatic uterine fibroids. SETTING: 20 Chinese hospitals. POPULATION OR SAMPLE: 2411 Chinese women with symptomatic fibroids...
April 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28413041/defining-cervical-elongation-a-prospective-observational-study
#4
Patrick A Nosti, Robert E Gutman, Cheryl B Iglesia, Amy J Park, Eshetu Tefera, Andrew I Sokol
OBJECTIVES: Our primary aim was to define cervical elongation (CE) using the following methods: (1) measurement of pathology specimen, (2) physician perception, (3) intraoperative estimate of anterior cervical length, and (4) office Pelvic Organ Prolapse Quantification (POP-Q) points C and D. Our secondary aim was to determine whether these definitions correlate with perioperative outcomes. METHODS: Women undergoing vaginal hysterectomy and prolapse repair were enrolled...
April 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28411085/vaginal-myomectomy-using-d%C3%A3-hrssen-longitudinal-median-cervical-incision-a-case-series-of-19-patients
#5
Wai Yoong, Wei Zhao, Hong Cai, Robyn D'Cruz, Alessia Corrieri, John Hamilton, Abiodun Fakokunde
STUDY OBJECTIVE: To examine demographics and outcome measures of women having undergone vaginal excision of myoma through Dührssen (longitudinal median cervical) incision DESIGN: Prospective case series DESIGN CLASSIFICATION: The design of the study conforms to Canadian Task Force II3 ie evidence from timed series SETTING: A London teaching hospital PATIENTS: 19 patients with either a) submucus myoma (type 1) located near the cervix or b) pedunculated intracavity myoma (type 0), excised via Dührssen incision INTERVENTIONS: Dührssen (median longitudinal) incision on the anterior or posterior cervical lip MEASUREMENTS: Duration of procedure, intraoperative complications, estimated blood loss, length of stay, % 24 hour discharge, readmission rates RESULTS: Between 2009-16, 19 women had their myomas (submucus type 1, n=17; pedunculated intracavity type 0, n=2) removed vaginally via Dührssen incision...
April 11, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28406809/hysteroscopy-for-abnormal-uterine-bleeding-and-fibroids
#6
Lindsey N Valentine, Linda D Bradley
Operative hysteroscopy is a safe and effective minimally invasive treatment option for submucosal and intramural leiomyomas. We discuss preoperative evaluation, fluid management, postoperative complications, preventative measures, and hysteroscopic outcomes. Technical instructions and tips for successful hysteroscopy, as well as the various equipment options most commonly utilized in the United States, are also reviewed.
June 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28403922/place-of-ulipristal-acetate-in-the-management-of-uterine-fibroids-preoperative-treatment-or-sequential-treatment
#7
A-G Pourcelot, P Capmas, H Fernandez
Symptomatic uterine fibroids affect 25% of women of childbearing potential and are responsible for various symptoms, mainly menometrorrhagia, pelvic pain and infertility. No currently available medical treatment is able to eradicate fibroids. Two treatments are indicated preoperatively to reduce bleeding and decrease the size of fibroids: GnRH agonists and ulipristal acetate. Ulipristal acetate, a selective progesterone receptor modulator, exerts an antagonist effect on fibroid tissue, inducing apoptosis. It rapidly induces amenorrhoea (after an average of seven days of treatment) and reduces fibroid volume...
March 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28400352/frequency-of-uterine-sarcomas-in-patients-admitted-for-uterine-fibroids-surgery
#8
Liselotte Mettler, Nicolai Maass, Khulkar Abdusattarova, Astrid Dempfle, Ibrakhim Alkatout
OBJECTIVE: To estimate the frequency of unsuspected uterine sarcoma identified postoperatively in women undergoing surgery for presumed benign uterine fibroids at the single-center university hospital. MATERIAL AND METHODS: This was a retrospective single-center study; the records of all 2,275 patients with uterine fibroids and uterine sarcomas from 2003 to 2015 were reviewed. Descriptive statistics were used to analyze demographic and clinical characteristics. To calculate confidence intervals (CIs), the exact Clopper-Pearson method was applied...
February 7, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/28399866/evaluating-the-role-of-race-and-medication-in-protection-of-uterine-fibroids-by-type-2-diabetes-exposure
#9
Digna R Velez Edwards, Katherine E Hartmann, Melissa Wellons, Anushi Shah, Hua Xu, Todd L Edwards
BACKGROUND: Uterine fibroids (UF) affect 77% of women by menopause, and account for $9.4 billion in annual healthcare costs. Type-2-diabetes (T2D) has inconsistently associated with protection from UFs in prior studies. To further evaluate the relationship between T2D and UFs we tested for association between T2D and UF risk in a large clinical population as well as the potential differences due to T2D medications and interaction with race. METHODS: This nested case-control study is derived from a clinical cohort...
April 11, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28397200/impact-of-pelvic-magnetic-resonance-imaging-findings-in-the-indication-of-uterine-artery-embolization-in-the-treatment-of-myoma
#10
Norma Maria Tenório Brito Pires, Emmanuelle Tenório Godoi, Dinaldo Cavalcanti Oliveira, Simone Cristina Soares Brandão, Carlos Coutinho Abath, Pedro Pires, Edward Araujo Júnior
OBJECTIVES: To assess the impact of pelvic magnetic resonance imaging (MRI) findings in the indication for uterine-artery embolization in women with fibroids, as well as the correlation between MRI and ultrasound (US) examinations for diagnosing adenomyosis. MATERIAL AND METHODS: A retrospective observational study was performed through the analysis of the medical records of 263 women referred for uterine-artery embolization as treatment for fibroids after undergoing US and MRI examinations...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28385588/outcomes-of-elective-outpatient-hysteroscopic-sterilization-in-undocumented-women-a-retrospective-analysis
#11
Patsy J McGuire, Jennifer Butler, Christina Gavito, Jeanelle Sheeder, Kristina Tocce
OBJECTIVE: To determine the feasibility of hysteroscopic sterilization in low-income and unauthorized immigrant women when financial barriers to care are removed. METHODS: Outpatient hysteroscopic sterilization for low-income women at an urban clinic was made possible by grant funding. All procedures were performed by obstetrician/gynecologist attending physicians or supervised trainees. Electronic records were reviewed for cases performed from June 2010 to December 11, 2013...
April 3, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28373777/dynamic-enhanced-computed-tomography-imaging-findings-of-an-inflammatory-fibroid-polyp-with-massive-fibrosis-in-the-stomach
#12
Eun Jung Shim, Sung Eun Ahn, Dong Ho Lee, Seong Jin Park, Youn Wha Kim
Inflammatory fibroid polyp (IFP) is a rare benign lesion of the gastrointestinal tract. We report a case of computed tomography (CT) imaging finding of a gastric IFP with massive fibrosis. CT scans showed thickening of submucosal layer with overlying mucosal hyperenhancement in the gastric antrum. The submucosal layer showed increased enhancement on delayed phase imaging. An antrectomy with gastroduodenostomy was performed because gastric cancer was suspected, particularly signet ring cell carcinoma. The histopathological diagnosis was an IFP with massive fibrosis...
March 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28369817/giant-leiomyoma-with-extensive-myxoid-degeneration-in-mayer-rokitansky-k%C3%A3-ster-hauser-syndrome
#13
Richa Sharma, Kiran Guleria, Amita Suneja, Sruthi Bhaskaran, Nadeem Tanveer
Fibroids and fibroid degeneration are common among women with a normal uterus. However, the present report describes a rare case of fibroids arising from a rudimentary horn and degenerations in a patient with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. The patient provided consent for publication. A woman with MRKH syndrome aged 45 years presented at the gynecology outpatient department at University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India, with complaints of an abdominopelvic mass and pain for the previous 2 years...
March 31, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28357157/a-new-paradigm-for-uterine-fibroid-treatment-transcervical-intrauterine-sonography-guided-radiofrequency-ablation-of-uterine-fibroids-with-the-sonata-system
#14
REVIEW
David B Toub
PURPOSE OF REVIEW: This article provides the current evidence related to transcervical radiofrequency ablation of uterine fibroids under integrated intrauterine sonography guidance (the Sonata System). RECENT FINDINGS: Published data on the treatment of fibroids with the Sonata System has demonstrated significant median reductions in total (73.3%) and perfused (73.3%) uterine fibroid volume, menstrual bleeding (72.3%), symptom severity (62.5%), and improvements in health-related quality of life (127%) at 12 months post-ablation...
2017: Current Obstetrics and Gynecology Reports
https://www.readbyqxmd.com/read/28353387/recent-developments-in-surgical-pathology-of-the-uterine-corpus
#15
REVIEW
Krisztina Z Hanley, George G Birdsong, Marina B Mosunjac
There have been several updates recently on the classification of uterine tumors. Endometrial carcinomas have traditionally been divided into 2 types, but some are difficult to classify and do not fit readily into either of the currently recognized categories. The Cancer Genome Atlas Research Network has recently defined 4 new categories of endometrial cancer on the basis of mutational spectra, copy number alteration, and microsatellite instability, which might provide independent prognostic information beyond established risk factors...
April 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28351762/does-ulipristal-acetate-affect-surgical-experience-at-laparoscopic-myomectomy
#16
Lea Luketic, Lindsay Shirreff, Sari Kives, Grace Liu, Ramadan El Sugy, Nicholas Leyland, Meir Jonathon Solnik, Ally Murji
STUDY OBJECTIVE: To compare surgical experience of laparoscopic/robotic myomectomy in premenopausal patients pretreated with ulipristal acetate (UPA) with women not hormonally pretreated. DESIGN: Retrospective, multicenter cohort study of laparoscopic/robotic myomectomy procedure videos (Canadian Task Force Classification III). SETTING: Multiple university-affiliated tertiary care hospitals. PATIENTS: Fifty-five premenopausal women who underwent laparoscopic/robotic myomectomy for intramural fibroids and were either pretreated with 3-months of UPA or had no hormonal pretreatment...
March 25, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28350728/an-unusual-case-of-right-upper-quadrant-pain-in-a-pregnant-woman
#17
Veena Modayil, Mathew Nelson, Brendon Stankard
Uterine fibroids occur in up to 30% of women of reproductive age and can cause complications during pregnancy that can harm mother and fetus, such as prematurity and increased risk of miscarriage. This article describes a pregnant woman whose abdominal pain was diagnosed as degenerating uterine fibroids.
April 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28341966/efficacy-of-single-dose-gonadotropin-releasing-hormone-agonist-administration-prior-to-magnetic-resonance-guided-focused-ultrasound-surgery-for-symptomatic-uterine-fibroids
#18
Hyun Park, Sang Wook Yoon
PURPOSE: To investigate the effects of a single-dose GnRHa on the thermal ablation of MRgFUS in women with symptomatic fibroids. MATERIALS AND METHOD: In this pilot study, a single-dose GnRHa was administered in 17 patients with a total of 20 fibroids. Volume and scaled signal intensity (SSI) as an objective marker of fluid contents were prospectively followed up with serial MR scans. The control group of 17 patients with 19 fibroids were retrospectively enrolled and compared with GnRHa group in terms of non-perfused volume (NPV) and thermal dosimetry to assess the efficiency of thermal ablation...
March 24, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28338206/impact-and-clinical-significance-of-embosphere-microsphere-artery-embolization-therapy-in-serum-vegf-expression-level-of-women-patients-with-uterine-fibroids
#19
H-X Ge, W Xu, D-Q Du, A-J Wang
OBJECTIVE: We aimed to investigate the effect of Embosphere microsphere artery embolization on the serum level of vascular endothelial growth factor (VEGF) in patients with uterine fibroid. PATIENTS AND METHODS: From March 2014 to December 2015, 128 women in child-bearing age with uterine intramural fibroids were enrolled in the patient group. At the same time, 128 healthy cases in child-bearing age were randomly selected and enrolled in the control group. Enzyme-linked immunosorbent assay was used to measure the serum level of VEGF, and immunohistochemical staining method was used to study the expression of VEGF in the uterine fibroids...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28337095/routine-saline-infusion-sonohysterography-prior-to-assisted-conception-a-review-of-our-initial-experience
#20
G Obajimi, B Ogunkinle
Saline infusion sonohysterography has been employed to evaluate the uterine cavity prior to commencement of assisted conception.Intra-uterine lesions play an important role in the outcome of assisted conception procedures. A descriptive retrospective study of 760 patients who had saline infusion sonohysterography prior to assisted conception, between January 2008 and December, 2010. Forty-six percent of the patients had intra-uterine pathologies. Submucous fibroids accounted for almost half (48.57%) of the pathologies, followed by adhesions (28...
December 2016: Annals of Ibadan Postgraduate Medicine
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