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https://www.readbyqxmd.com/read/29161346/co-transplantation-of-nanofat-enhances-neovascularization-and-fat-graft-survival-in-nude-mice
#1
Qian Yu, Yizuo Cai, He Huang, Zhenxing Wang, Peng Xu, Xiangsheng Wang, Lu Zhang, Wenjie Zhang, Wei Li
Background: Autologous fat grafting is commonly used for soft-tissue augmentation and reconstruction. However, this technique is limited by a high rate of graft absorption. Thus, approaches to improve fat graft survival that promote neovascularization are of great interest. Nanofat has several beneficial features that may render it more suitable for clinical applications than other stem-cell based approaches. Objectives: We aimed to determine whether nanofat could enhance new vessel formation and improve the long-term retention of fat grafts...
November 17, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29147757/prospective-evaluation-of-co2-laser-assisted-sclerectomy-surgery-class-with-mitomycin-c
#2
Carlo Alberto Cutolo, Alessandro Bagnis, Riccardo Scotto, Chiara Bonzano, Carlo Enrico Traverso
PURPOSE: Our purpose was to evaluate the clinical safety and efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) with Mitomycin C (MMC) in open angle glaucoma (OAG). METHODS: This was a prospective, uncontrolled, interventional case series. All subjects underwent CLASS procedure by a single surgeon. After the dissection of a partial thickness scleral flap, topical MMC 0.2 mg/ml was applied to the sclera and the conjunctiva for 3 min. The CO2 laser with a beam-manipulating system was used to ablate the scleral tissue and expose the Schlemm's canal area...
November 17, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29145491/the-urine-biomarker-panel-igfbp7-x-timp-2-nephrocheck%C3%A2-parameter-does-not-correlate-with-igfbp7-and-timp-2-gene-expression-in-urinary-sediment
#3
Daniela Knafl, Markus Müller, Sahra Pajenda, Zeynep Genc, Manfred Hecking, Ludwig Wagner
BACKGROUND: Acute kidney injury (AKI) is frequently observed in serious infections, following nephrotoxic medication, surgery and trauma. Here we tested whether the detection of two recently identified biomarkers for AKI, Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) and Insulin-Like Growth Factor Binding Protein 7 (IGFBP7), depends on the expression of these proteins in cells of the urinary sediment. METHOD: We collected urine samples of 33 kidney transplant recipients and 14 non-transplanted patients who all had AKI (stages 1-3 according to KDIGO), and measured [IGFBP7]x[TIMP-2] using the NephroCheck® Astute1 40 ™ meter...
2017: PloS One
https://www.readbyqxmd.com/read/29138695/risk-factors-of-malignant-glaucoma-occurrence-after-glaucoma-surgery
#4
Karolina Krix-Jachym, Tomasz Żarnowski, Marek Rękas
Purpose: The aim of this study was twofold: first, to evaluate the predisposing factors for occurrence of malignant glaucoma and second, to compare frequency of malignant glaucoma depending on the type of primary glaucoma surgery. Methods: Retrospective analysis was performed in 1689 consecutive patients who underwent glaucoma surgery alone or combined with phacoemulsification. Data collected included the type of surgery, width of the filtration angle, presence or absence of malignant glaucoma in the postoperative period, and time from the primary surgery to malignant glaucoma occurrence...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29136246/renal-function-and-urological-complications-after-radical-hysterectomy-with-postoperative-radiotherapy-and-platinum-based-chemotherapy-for-cervical-cancer
#5
Masao Okadome, Toshiaki Saito, Shoko Kitade, Kazuya Ariyoshi, Kumi Shimamoto, Hiroyuki Kawano, Kazuhito Minami, Motonobu Nakamura, Mototsugu Shimokawa, Kazuhiro Okushima, Yuichiro Kubo, Naonobu Kunitake
Background: We aimed to clarify renal functional changes long term and serious urological complications in women with cervical cancer who undergo radical hysterectomy followed by pelvic radiotherapy and/or platinum-based chemotherapy to treat the initial disease. Methods: Data on 380 women who underwent radical hysterectomy at the National Kyushu Cancer Center from January 1997 to December 2013 were reviewed. Main outcome measures were the estimated glomerular filtration rate (eGFR) and monitored abnormal urological findings...
November 10, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29135137/-renal-function-after-laparoscopic-partial-nephrectomy-with-superselective-balloon-embolization-of-renal-artery
#6
A V Maksimov, A G Martov, L P Pavlov
AIM: To evaluate the functional state of the renal parenchyma after partial nephrectomy, depending on surgical technique. MATERIALS AND METHODS: The study comprised 21 patients with kidney neoplasms of stage T1-2N0M0. The patients underwent either laparoscopic partial nephrectomy with superselective balloon embolization of the renal artery (study group, n=11), or partial nephrectomy with vascular clamping (control group, n=10). The mean age of the patients in the study group (3 men and 8 women) was 56...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29131092/value-of-intraoperative-parathyroid-hormone-assay-during-parathyroidectomy-in-dialysis-and-renal-transplant-patients-with-secondary-and-tertiary-hyperparathyroidism
#7
Amr El-Husseini, Kevin Wang, Annick Edon, David Saxon, Florence Lima, David Sloan, B Peter Sawaya
BACKGROUND: In dialysis and renal transplant patients with secondary and tertiary hyperparathyroidism (HPT), the value of intraoperative parathyroid hormone (ioPTH) during parathyroidectomy (PTX) and its association with long-term PTH levels are unknown. The present study aims at evaluating the relationship of ioPTH with long-term PTH levels post-PTX in dialysis and renal transplant patients in a single-center study. METHODS: The ioPTH was measured in 57 dialysis patients (33 females and 24 males) and 18 renal transplant recipients (12 males and 6 females) who underwent PTX from 2005 to 2015 for refractory HPT...
November 9, 2017: Nephron
https://www.readbyqxmd.com/read/29128188/influence-of-concurrent-chronic-kidney-disease-on-intraoperative-parathyroid-hormone-monitoring-during-parathyroidectomy-for-primary-hyperparathyroidism
#8
Bipin Sunkara, Mark S Cohen, Barbra S Miller, Paul G Gauger, David T Hughes
BACKGROUND: The influence of chronic kidney disease on intraoperative parathyroid hormone monitoring during parathyroidectomy for primary hyperparathyroidism has not been well-established. We hypothesize that chronic kidney disease influences intraoperative parathyroid hormone degradation kinetics during parathyroidectomy. METHODS: This is a single institution retrospective cohort study of consecutive patients with primary hyperparathyroidism underdoing parathyroidectomy...
November 8, 2017: Surgery
https://www.readbyqxmd.com/read/29112549/european-guidelines-on-perioperative-venous-thromboembolism-prophylaxis-patients-with-preexisting-coagulation-disorders-and-after-severe-perioperative-bleeding
#9
Aamer Ahmed, Sibylle Kozek-Langenecker, François Mullier, Sue Pavord, Cedric Hermans
: In patients with inherited bleeding disorders undergoing surgery, we recommend assessment of individual risk for venous thromboembolism, taking into account the nature of the surgery and anaesthetic, type and severity of bleeding disorder, age, BMI, history of thrombosis, the presence of malignancy and other high-risk comorbidities. Venous thromboembolism risk should be balanced against the increased bleeding risk associated with anticoagulant use in patients with known bleeding disorders (Grade 1C). In these patients undergoing major surgery, we recommend against routine postoperative use of pharmacological thromboprophylaxis, especially for patients with haemophilia A and B (Grade 1B)...
November 6, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29107998/impact-of-surgical-parathyroidectomy-on-chronic-kidney-disease-mineral-and-bone-disorder-ckd-mbd-a-systematic-review-and-meta-analysis
#10
Mugurel Apetrii, David Goldsmith, Ionut Nistor, Dimitrie Siriopol, Luminita Voroneanu, Dragos Scripcariu, Marc Vervloet, Adrian Covic
For more than 6 decades, many patients with advanced chronic kidney disease (CKD) have undergone surgical parathyroidectomy (sPTX) for severe secondary hyperparathyroidism (SHPT) mainly based historical clinical practice patterns, but not on evidence of outcome.We aimed in this meta-analysis to evaluate the benefits and harms of sPTX in patients with SHPT. We searched MEDLINE (inception to October 2016), EMBASE and Cochrane Library (through Issue 10 of 12, October 2016) and website clinicaltrials.gov (October 2016) without language restriction...
2017: PloS One
https://www.readbyqxmd.com/read/29102929/three-dimensional-laser-scanning-confocal-analysis-of-conjunctival-microcysts-in-glaucomatous-patients-before-and-after-trabeculectomy
#11
Silvio DI Staso, Luca Agnifili, Angela DI Gregorio, Hilary Climastone, Emilio Galassi, Vincenzo Fasanella, Marco Ciancaglini
BACKGROUND/AIM: In glaucoma, conjunctival epithelial microcysts (CEM) have been extensively investigated by means of laser scanning confocal microscopy. In the present case series, we examined eight glaucomatous patients undergoing trabeculectomy to obtain a 3-dimensional (3-D) characterization of CEM. MATERIALS AND METHODS: Image acquisition was performed in z-scan automatic volume mode by Heidelberg Retina Tomograph III/Rostock Cornea Module and a series of 40 images of 300×300 μm (384×384 pixels) to a maximum depth of 40 μm were acquired throughout the upper bulbar conjunctiva before (at the site planned for surgery) and eight weeks after trabeculectomy...
November 2017: In Vivo
https://www.readbyqxmd.com/read/29096686/vaso-vitamin-d-and-arthroplasty-surgery-outcomes-study-supplementation-of-vitamin-d-deficiency-to-improve-outcomes-after-total-hip-or-knee-replacement-study-protocol-for-a-randomised-controlled-feasibility-trial
#12
Rory J M Morrison, Deborah Bunn, William K Gray, Paul N Baker, Craig White, Amar Rangan, Kenneth S Rankin, Mike R Reed
BACKGROUND: Vitamin D deficiency has been linked to poor outcomes after total hip replacement (THR) or total knee replacement (TKR), including lower patient-reported outcome measures (PROMs), peri-prosthetic infection and longer hospital stay. We present a randomised feasibility trial protocol designed to prospectively investigate the influence of vitamin D testing, and subsequent supplementation for deficiency, prior to THR/TKR. METHODS/DESIGN: One hundred adult patients undergoing primary THR/TKR for osteoarthritis at two NHS hospital trusts in North East England will be recruited...
November 2, 2017: Trials
https://www.readbyqxmd.com/read/29092632/comparison-of-kidney-function-in-the-early-postoperative-period-in-transperitoneal-robot-assisted-laparoscopic-partial-nephrectomy-between-anterior-and-posterior-renal-tumors-a-propensity-score-matched-study
#13
Toshio Takagi, Tsunenori Kondo, Kazuhiko Yoshida, Hirohito Kobayashi, Junpei Iizuka, Masayoshi Okumi, Hideki Ishida, Kazunari Tanabe
Objective To compare early postoperative renal function in transperitoneal robot assisted laparoscopic partial nephrectomy (RAPN) for anterior and posterior renal tumors. Patients and Methods This study included 227 patients who underwent transperitoneal RAPN for anterior or posterior renal tumors. Tumor position was defined by RENAL nephrometry score. To minimize selection bias between anterior and posterior tumors, patient variables were adjusted using 1:1 propensity score matching. Results Of the 227 patients, 125 were classified as having anterior tumors and 102 as having posterior tumors...
November 1, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29090048/water-drinking-test-intraocular-pressure-changes-after-tube-surgery-and-trabeculectomy
#14
Mohammad Reza Razeghinejad, Zahra Tajbakhsh, Mohammad Hossein Nowroozzadeh, Masoumeh Masoumpour
PURPOSE: To study the effects of filtration surgeries (tube and trabeculectomy) on changes in intraocular pressure after a water-drinking test. METHODS: In this prospective, non-randomized, comparative clinical study, 30 patients who had tube surgery and 30 age- and sex-matched trabeculectomy patients underwent a water-drinking test. Only one eye of each patient was included. The baseline intraocular pressure was ≤21 mmHg in all enrolled eyes with or without adjunctive topical medications...
October 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29079272/modulation-of-fibroblasts-in-conjunctival-wound-healing
#15
REVIEW
Mark Zada, Ushasree Pattamatta, Andrew White
Modulating conjunctival wound healing has the potential to improve outcomes after glaucoma filtration surgery and for several ocular disorders, including ocular cicatrial pemphigoid, vernal keratoconjunctivitis, and pterygium. Although anti-inflammatories and antimetabolites have been used with success, these nonspecific agents are not without their complications. The search for novel and more targeted means to control conjunctival fibrosis without such limitations has brought much attention to the regulation of fibroblast proliferation, differentiation, extracellular matrix production, and apoptosis...
October 24, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29078630/robotic-thymectomy-a-new-approach-for-thymus
#16
REVIEW
Erkan Kaba, Tugba Cosgun, Kemal Ayalp, Mazen Rasmi Alomari, Alper Toker
Advancements in modern technology bring many evolutions in minimally invasive surgery such as robot assisted approaches. Because of complete resection is so important in thymectomy operations, they became a new era for robotic surgery as a result of its superiorities (intuitive movements, tremor filtration, more degrees of manipulative freedom, motion scaling, and high-definition stereoscopic vision).
2017: J Vis Surg
https://www.readbyqxmd.com/read/29064872/no-differences-in-renal-function-between-balanced-6-hydroxyethyl-starch-130-0-4-and-5-albumin-for-volume-replacement-therapy-in-patients-undergoing-cystectomy-a-randomized-controlled-trial
#17
Tobias Kammerer, Florian Brettner, Sebastian Hilferink, Nikolai Hulde, Florian Klug, Judith Pagel, Alexander Karl, Alexander Crispin, Klaus Hofmann-Kiefer, Peter Conzen, Markus Rehm
BACKGROUND: The use of artificial colloids has declined in critical care, whereas they are still used in perioperative medicine. Little is known about the nephrotoxic potential in noncritically ill patients during routine surgery. The objective of this trial was to evaluate the influences of albumin 5% and balanced hydroxyethyl starch 6% (130/0.4) on renal function and kidney injury. METHODS: One-hundred urologic patients undergoing elective cystectomy were randomly assigned for this prospective, single-blinded, controlled study with two parallel groups to receive either albumin 5% or balanced hydroxyethyl starch 6% (130/0...
October 24, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29062446/the-effect-of-zero-ischaemia-laparoscopic-minimally-invasive-partial-nephrectomy-using-the-modified-sequential-preplaced-suture-renorrhaphy-technique-on-long-term-renal-functions
#18
Mehmet Giray Sönmez, Cengiz Kara
INTRODUCTION: Laparoscopic minimally invasive partial nephrectomy (MIPN) is the preferred technique in renal surgery, especially T1 phase kidney tumours, and it is recommended for the protection of renal functions in methods that do not involve ischaemia. AIM: To evaluate long-term renal functions of zero-ischaemia laparoscopic MIPN patients who underwent a modified sequential preplaced suture renorrhaphy technique. MATERIAL AND METHODS: In a total of 17 renal units in 16 patients with kidney tumours that were determined incidentally and did not cause any complaints, the masses were extracted via laparoscopic partial nephrectomy (LPN) using the modified sequential preplaced suture renorrhaphy technique...
September 2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/29049166/safety-of-potassium-bearing-citrate-in-patients-with-renal-transplantation-a-case-report
#19
Lin Wang, Yinglin Cui, Jianwei Zhang, Qinsheng Zhang
RATIONALE: Urinary lithiasis is one of severe postoperative complications in patients undergoing renal transplantation, possibly leading to anuria, urinary infection, or even acute renal failure. Potassium sodium hydrogen citrate (PSHC), a potassium-bearing citrate, is commonly prescribed to prevent stone formation. PATIENT CONCERNS: A 25-year-old man (patient 1) and a 31-year-old man (patient 2) receiving renal transplantation for end-stage renal disease (ESRD) were enrolled in this study...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29048228/predictive-factors-for-achieving-superior-pentafecta-outcomes-following-robot-assisted-partial-nephrectomy-in-patients-with-localized-renal-cell-carcinoma
#20
Minyong Kang, In-Hyuck Gong, Hwi Jun Park, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Seong Il Seo
PURPOSE: To examine the perioperative outcomes following robot-assisted partial nephrectomy (RAPN) in patients with localized renal cell carcinoma (RCC) and to identify the predictors of Pentafecta achievement following RAPN. MATERIALS AND METHODS: We retrospectively analyzed the data from 362 patients with RCC who underwent RAPN from 2008 to 2016. The criteria for Pentafecta achievement was defined as the Trifecta [warm ischemia time (WIT) ≤ 25 minutes, negative surgical margin, and no significant perioperative complications]; with the addition of renal function preservation, including over 90% preservation of the estimated-glomerular filtration rate (e-GFR); and no stage upgrade of chronic kidney disease at 1 year after surgery...
October 19, 2017: Journal of Endourology
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