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https://www.readbyqxmd.com/read/27927587/estimated-gfr-before-and-after-bariatric-surgery-in-ckd
#1
Talha H Imam, Heidi Fischer, Bocheng Jing, Raoul Burchette, Shayna Henry, Stephen F DeRose, Karen J Coleman
BACKGROUND: Several reviews have recently detailed the beneficial effects of weight loss surgery for kidney function. However, these studies have a number of limitations, including small sample size, few done in chronic kidney disease (CKD) stages 3 and 4, and many not including the main bariatric surgery procedures used in the United States today. STUDY DESIGN: This was an observational retrospective cohort study comparing propensity score-matched bariatric surgery patients and nonsurgery control patients who were referred for, but did not have, surgery...
December 4, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27925145/the-oldest-old-in-the-emergency-department-impact-of-renal-function
#2
T Brünnler, M Drey, G Dirrigl, C Weingart, F Rockmann, C Sieber, U Hoffmann
OBJECTIVES: The ageing population implicates an increasing numbers of older adults attending Emergency Departments (ED). We assessed the effect of estimated glomerular filtration rate as a predictor of clinical outcomes in oldest-old patients ≥ 85 years attending the ED in an university teaching hospital. DESIGN: Within three years, 81831 patient contacts were made in our ED. 7799 (9.5%) were older than 85 years, in whom we analyzed the impact of renal function on various outcome parameters...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27921038/the-clinical-manifestation-and-management-of-autosomal-dominant-polycystic-kidney-disease-in-china
#3
REVIEW
Cheng Xue, Chen-Chen Zhou, Ming Wu, Chang-Lin Mei
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic hereditary kidney disease characterized by progressive enlargement of renal cysts. The incidence is 1-2‰ worldwide. Mutations in two genes (PKD1 and PKD2) cause ADPKD. Currently, there is no pharmaceutical treatment available for ADPKD patients in China. Summary: This review focused on advances in clinical manifestation, gene diagnosis, risk factors, and management of ADPKD in China. There is an age-dependent increase in total kidney volume (TKV) and decrease in renal function in Chinese ADPKD patients...
October 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27916028/-structured-training-strategy-for-robot-surgery
#4
H Q Xi, K C Zhang, B Wei, L Chen
With surgical strategy progresses towarding to precision and minimally invasive surgery, the Da Vinci robotic surgical system comes into being. Compared with conventional surgery, the Da Vinci robotic surgical system enjoys several advantages including clear operation field, flexibility and tremor filtration.Normative operation plays an important role in translating such advantages into clinical benefits.Training physicians systematically and comprehensively is very important. Compared with conventional training strategy, multi-modal simulation training is more preferred for the Da Vinci robotic surgical system training...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27914704/kidney-outcomes-three-years-after-bariatric-surgery-in-severely-obese-adolescents
#5
Edward J Nehus, Jane C Khoury, Thomas H Inge, Nianzhou Xiao, Todd M Jenkins, Marva M Moxey-Mims, Mark M Mitsnefes
A significant number of severely obese adolescents undergoing bariatric surgery have evidence of early kidney damage. To determine if kidney injury is reversible following bariatric surgery, we investigated renal outcomes in the Teen-Longitudinal Assessment of Bariatric Surgery cohort, a prospective multicenter study of 242 severely obese adolescents undergoing bariatric surgery. Primary outcomes of urine albumin-to-creatinine ratio and cystatin C-based estimated glomerular filtration rate (eGFR) were evaluated preoperatively and up to 3 years following bariatric surgery...
November 30, 2016: Kidney International
https://www.readbyqxmd.com/read/27908680/the-effect-of-contralateral-kidney-volume-on-renal-function-after-radical-nephroureterectomy-implications-for-eligibility-for-neoadjuvant-chemotherapy-for-upper-tract-urothelial-cancer
#6
Wan Song, Hyun Hwan Sung, Deok Hyun Han, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Hwang Gyun Jeon
PURPOSE: We investigated the effect of preoperative contralateral kidney (CK) volume on renal function after radical nephroureterectomy (RNU). METHODS: We reviewed 630 patients who underwent RNU between September 1994 and December 2013. Of these 630 patients, 135 patients with advanced upper tract urothelial cancer were ultimately included. Preoperative CK volume was measured from computed tomography images of the venous phase using a specialized volumetric program...
November 28, 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27907917/simple-cysts-in-donor-kidney-contribute-to-reduced-allograft-function
#7
Wenxian Qiu, Yan Jiang, Jianyong Wu, Hongfeng Huang, Wenqing Xie, Xishao Xie, Jianghua Chen, Wenhan Peng
BACKGROUND: Simple renal cysts may be an early marker of renal disease. We investigated whether simple cysts in donor kidney are associated with the decline of allograft function in living donor kidney transplantation. METHODS: We retrospectively reviewed records of donors and recipients from 716 living donor kidney transplants performed between April 2007 and April 2015 in our hospital. Ninety-one donors with renal cysts and 64 recipients with cysts in donor kidney were noted...
December 2, 2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27906706/effects-of-cardiopulmonary-bypass-on-renal-perfusion-filtration-and-oxygenation-in-patients-undergoing-cardiac-surgery
#8
Lukas Lannemyr, Gudrun Bragadottir, Vitus Krumbholz, Bengt Redfors, Johan Sellgren, Sven-Erik Ricksten
BACKGROUND: Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass. The authors evaluated the effects of normothermic cardiopulmonary bypass on renal blood flow, glomerular filtration rate, renal oxygen consumption, and renal oxygen supply/demand relationship, i.e., renal oxygenation (primary outcome) in patients undergoing cardiac surgery. METHODS: Eighteen patients with a normal preoperative serum creatinine undergoing cardiac surgery procedures with normothermic cardiopulmonary bypass (2...
December 1, 2016: Anesthesiology
https://www.readbyqxmd.com/read/27903484/loss-of-kidney-function-after-endovascular-treatment-of-peripheral-arterial-disease
#9
T A Sigterman, L J J Bolt, A G Krasznai, M G Snoeijs, R Heijboer, G W H Schurink, L H Bouwman
BACKGROUND: Administration of radiocontrast during endovascular procedures for peripheral arterial disease may cause acute kidney injury, which generally recovers with supportive treatment. Long-term effects of endovascular procedures on renal function remain to be investigated. METHOD: This retrospective observational cohort study includes all patients who newly presented to the vascular surgery outpatient clinic with rutherford class II or III peripheral arterial disease and who were treated with either supervised exercise therapy or endovascular interventions...
November 26, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27901623/autotransplantation-of-spleen-mitigates-drug-induced-liver-damage-in-splenectomized-mice
#10
Sabrine Teixeira Ferraz Grunewald, Alice Belleigoli Rezende, Bárbara Bruna Muniz Figueiredo, Ana Carolina de Paula Mendonça, Caroline de Souza Almeida, Erick Esteves de Oliveira, Flávia de Paoli, Henrique Couto Teixeira
PURPOSE: The spleen presents numerous functions, including the production of immunoglobulins and blood filtration, removing microorganisms and cellular debris. The spleen also has anatomical and functional relationship with the liver, but there are few studies on this topic. The aim of this study was to assess the effect of splenectomy and autologous spleen transplantation on both filtering functions of spleen and acetaminophen-induced hepatotoxicity. MATERIALS AND METHODS: Fifty-two BALB/c mice were randomized into four groups: splenectomized; splenectomy and splenic autotransplantation in the greater omentum; sham operated control; and non-operated control...
November 30, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/27898468/update-on-ciliary-body-laser-procedures
#11
Behzad Amoozgar, Eileen N Phan, Shan C Lin, Ying Han
PURPOSE OF REVIEW: There are currently various options available for glaucoma treatment procedures ranging from laser to penetrating to nonpenetrating surgeries. Innovations in glaucoma surgical therapeutics include features such as external application, focused tissue effects, and minimal manipulation as these factors all help lower the risk of side-effects in addition to increasing the success rate of the treatment. Traditional diode laser transscleral cyclophotocoagulation (TSCPC) is invasive and destructive...
November 25, 2016: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27896648/clinical-and-metabolic-effects-of-biliopancreatic-diversion-persist-after-reduction-of-the-gastric-pouch-and-elongation-of-the-common-alimentary-tract-preliminary-report-in-a-series-of-patients-with-a-10-year-follow-up
#12
Valerio Ceriani, Francesco Cetta, Tiziana Lodi, Ferdinando Pinna, Antonio E Pontiroli
BACKGROUND: Biliopancreatic diversion (BPD) is a bariatric technique burdened, in some instances, by clinical evidence of malabsorption and malnutrition, and by intractable diarrhea. OBJECTIVE: The objective of this study was to assess metabolic and nutritional effects on patients undergoing BPD and BPD plus revisional surgery because of side effects. METHODS: Thirty-five consecutive BPD patients underwent revisional surgery (elongation of the common limb from 50 to 200 cm and reduction of the gastric pouch from 500 to 40 ml) after a median 48-month period [48...
November 29, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27893886/integrin-%C3%AE-5%C3%AE-1-inhibition-by-clt-28643-reduces-postoperative-wound-healing-in-a-mouse-model-of-glaucoma-filtration-surgery
#13
Tine Van Bergen, Grit Zahn, Patrizia Caldirola, Mario Fsadni, Ninus Caram-Lelham, Evelien Vandewalle, Lieve Moons, Ingeborg Stalmans
Purpose: To evaluate the therapeutic potential of the small molecule integrin α5β1 inhibitor, CLT-28643, to improve the filtering surgery outcome in a mouse model. Different dose regimens and administration routes of the inhibitor were compared with mitomycin C (MMC), the gold standard in clin ical practice. Methods: The efficacy of CLT-28643 on surgical outcome was studied in a mouse model for filtering surgery (n = 40 eyes from 20 mice per group). Single and repeated subconjunctival (SCJ) injections (1 or 2 μg) and topical eye drops (10 μg) of the integrin inhibitor were compared with 2-minute administration of MMC 0...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27890838/preoperative-evaluation-of-the-renal-function-before-the-treatment-of-abdominal-aortic-aneurysms
#14
Raphael Coscas, Sandra Wagner, Eve Vilaine, Albane Sartorius, Isabelle Javerliat, Olivier Goeau-Brissonniere, Marc Coggia, Ziad Massy
OBJECTIVES: Chronic impaired renal function (IRC) constitutes a major risk factor of morbi-mortality during the treatment of an abdominal aortic aneurism (AAA). The inflammatory state due to the AAA could result in a reduction in the muscular mass and an over-estimation of the glomerular filtration rate (GFR) with the usual formulas. The objective of this study was to determine if the formulae used to evaluate the estimated GFR were adapted in patients with AAA. MATERIALS AND METHODS: Between August 2013 and November 2014, we conducted an exploratory study to evaluate the renal function before surgery for AAA in 28 patients...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27885452/the-zero-ischemia-index-zii-a-novel-criterion-for-predicting-complexity-and-outcomes-of-off-clamp-partial-nephrectomy
#15
Yaohui Li, Lin Zhou, Tingchang Bian, Zhuoyi Xiang, Yeqing Xu, Yanjun Zhu, Xiaoyi Hu, Shuai Jiang, Jianming Guo, Hang Wang
PURPOSES: Although several anatomical classification systems that aimed to standardize the description of renal tumors were previously reported, a special classification system is required to help predict the complexity and perioperative outcomes of off-clamp nephron-sparing surgery (NSS). We developed a novel criterion-zero ischemia index (ZII), aiming to help predict the perioperative outcomes after off-clamp NSS and guide patient selection. METHODS: We retrospectively evaluated 149 patients between June 2009 and July 2014 in our institution who underwent off-clamp NSS with available computed tomography images...
November 24, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27881019/comparative-analysis-of-renal-functional-outcomes-and-overall-survival-of-elderly-vs-non-elderly-patients-undergoing-radical-nephrectomy
#16
Charles Christopher Peyton, Michael Rothberg, Victoria Jiang, Matthew Heavner, Ashok Hemal
PURPOSE: To evaluate changes in renal function and overall survival in elderly vs. non-elderly patients undergoing radical nephrectomy for renal masses. PATIENTS AND METHODS: We reviewed available records of 392 patients undergoing radical nephrectomy from 2008 through 2013. Patients were divided into elderly, defined as ≥ 70 years old (n = 110), or non-elderly (n = 282) at the time of nephrectomy. The groups were compared for perioperative characteristics, renal functional outcomes and overall survival...
November 23, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27878419/split-renal-function-of-both-kidneys-after-robot-assisted-partial-nephrectomy-for-renal-tumor-larger-than-4%C3%A2-cm
#17
Sheng-Han Tsai, Yi-Chen Lai, Nai-Yuan Wu, Hsiao-Jen Chung
PURPOSE: Relative few studies reported the changes in split renal function using renal scintigraphy for robot-assisted partial nephrectomy (RaPN) for renal tumor >4 cm. This study aimed at demonstrating that RaPN is safe for renal tumor >4 cm without damaging the renal function of ipsilateral and contralateral kidney. METHODS: Patients who underwent RaPN for single renal tumor from December 2009 to December 2013 were identified from a prospectively collected database...
November 22, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27876524/lower-extremity-weakness-is-associated-with-elevated-blood-and-cerebrospinal-fluid-glucose-levels-following-multibranched-endovascular-aortic-aneurysm-repair
#18
Jade S Hiramoto, Charlene Fernandez, Warren Gasper, Shant Vartanian, Linda Reilly, Timothy Chuter
OBJECTIVE: Hyperglycemia is associated with worsened clinical outcomes after central nervous system injury. The purpose of this study was to examine the association between lower extremity weakness (LEW) and the glucose levels of blood and cerebrospinal fluid (CSF) in patients undergoing multibranched endovascular aneurysm repair (MBEVAR) of thoracoabdominal and pararenal aortic aneurysms. METHODS: Blood and CSF samples were collected preoperatively, immediately after aneurysm repair, and on postoperative day 1 in 21 patients undergoing MBEVAR...
November 19, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27873153/preoperative-determinant-of-early-postoperative-renal-function-following-radical-cystectomy-and-intestinal-urinary-diversion
#19
Tatsuo Gondo, Yoshio Ohno, Jun Nakashima, Takeshi Hashimoto, Yoshihiro Nakagami, Masaaki Tachibana
PURPOSE: To identify preoperative factors correlated with postoperative early renal function in patients who had undergone radical cystectomy (RC) and intestinal urinary diversion. METHODS: We retrospectively identified 201 consecutive bladder cancer patients without distant metastasis who had undergone RC at our institution between 2003 and 2012. The estimated glomerular filtration rate (eGFR) was calculated using the modified Chronic Kidney Disease Epidemiology equation before RC and 3 months following RC...
November 21, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27861446/preoperative-renal-insufficiency-underreporting-and-association-with-readmission-and-major-postoperative-morbidity-in-an-academic-medical-center
#20
Jeanna D Blitz, Marny H Shoham, Yixin Fang, Venod Narine, Neeraj Mehta, Beamy S Sharma, Paul Shekane, Samir Kendale
BACKGROUND: Making a formal diagnosis of chronic kidney disease (CKD) in the preoperative setting may be challenging because of lack of longitudinal data. We explored the predictive value of a single reduced preoperative estimated glomerular filtration rate (eGFR) value on adverse patient outcomes in the first 30 days after elective surgery. We compared the rate of major postoperative adverse events, including 30-day readmission rate, hospital length of stay, infection, acute kidney injury (AKI), and myocardial infarction across patients with declining preoperative eGFR values...
December 2016: Anesthesia and Analgesia
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