keyword
https://read.qxmd.com/read/38528883/risk-factors-for-30-days-mortality-after-proximal-femoral-fracture-surgery-a-cohort-study
#1
JOURNAL ARTICLE
Eveline de Haan, Gert R Roukema, Veronique A J I M van Rijckevorsel, Tjallingius M Kuijper, Louis de Jong
PURPOSE: The primary objective of this study was to identify new risk factors and to confirm previously reported risk factors associated with 30-day mortality after hip fracture surgery. PATIENTS AND METHODS: A prospective hip fracture database was used to obtain data. In total, 3523 patients who underwent hip fracture surgery between 2011 and 2021 were included. Univariable and multivariable logistic regression was used to screen and identify candidate risk factors...
2024: Clinical Interventions in Aging
https://read.qxmd.com/read/38526448/linking-renal-hypoxia-and-oxidative-stress-in-chronic-kidney-disease-based-on-clinical-subjects-and-animal-models
#2
JOURNAL ARTICLE
Yizeng Xu, Fang Lu, Meng Wang, Lingchen Wang, Chaoyang Ye, Shuohui Yang, Chen Wang
This study aims to explore the relationships between renal function, hypoxia, and oxidative stress in chronic kidney disease (CKD). Seventy-six non-dialysis patients with CKD stages 1-5 and eight healthy subjects were included in the clinical research. They were divided into three groups: healthy subjects, CKD stages 1-3, and CKD stages 4-5. In the animal study, 16 rat models of CKD were established through 5/6 renal ablation/infarction (A/I) surgery, and 8 normal rats were split into 3 groups: Sham, CKD, and losartan groups...
March 24, 2024: Biomol Biomed
https://read.qxmd.com/read/38518208/weight-based-dosing-for-low-molecular-weight-heparin-enoxaparin-administration-to-achieve-optimal-vte-prophylaxis-in-trauma-patients
#3
JOURNAL ARTICLE
Tarendeep Thind, Thomas Heye, Curran Henson, Rebecca Reif, Hanna K Jensen, Kyle J Kalkwarf, Avi Bhavaraju, Ronald Robertson, Allison Jenkins
INTRODUCTION: Patients admitted after traumatic injuries are at high risk for developing venous thromboembolism (VTE). Low-molecular-weight heparin (LMWH) is commonly used to prevent VTE in this patient population; however, the optimal dosing strategy has yet to be determined. To address this question, a fixed-dosing strategy of LMWH was compared to a weight-based dosing strategy of LMWH for VTE prophylaxis. METHODS: A retrospective, pre-post implementation cohort study compared a fixed vs a weight-based dosing strategy of LMWH for VTE prophylaxis...
March 22, 2024: American Surgeon
https://read.qxmd.com/read/38518154/percutaneous-nephrolithotomy-versus-open-surgery-in-the-treatment-of-urinary-calculi
#4
JOURNAL ARTICLE
Ruipeng Tang, Zhengjin Yi, Yong Wang, Li Wan, Xiangyu Liu, Shubin Wang, Chuan Xiao
OBJECTIVE: To evaluate the effectiveness of percutaneous nephrolithotomy (PCNL) compared with open surgery for urinary stone removal. METHODS: A total of 95 patients with urinary stones were screened for eligibility between October 2020 and December 2021. After excluding 5 patients who revoked their consent, 90 patients were randomized to receive either traditional open surgery (traditional group) or PCNL (PCNL group), with 45 patients in each group. In addition, the two groups received Shugan Qingre Tonglin decoction twice daily for 2 weeks...
March 22, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38515869/pathophysiological-roles-of-the-serum-acylcarnitine-level-and-acylcarnitine-free-carnitine-ratio-in-patients-with-cardiovascular-diseases
#5
JOURNAL ARTICLE
Takafumi Nakajima, Taira Fukuda, Ikuko Shibasaki, Syotaro Obi, Masashi Sakuma, Shichiro Abe, Hirotsugu Fukuda, Shigeru Toyoda, Toshiaki Nakajima
INTRODUCTION: L-carnitine exerts protective effects, such as maintaining mitochondrial functions and decreasing reactive oxygen species, while acylcarnitine (AC) is linked to the development of heart failure and atherosclerosis. HYPOTHESIS: Serum carnitines play important pathophysiological roles in cardiovascular diseases. METHODS: Pre-operative biochemical data were obtained from 117 patients (71 men, average age 69.9 years) who underwent surgery for cardiovascular diseases...
April 2024: IJC Heart & Vasculature
https://read.qxmd.com/read/38513672/plasma-hyperosmolality-during-cardiopulmonary-bypass-is-a-risk-factor-for-postoperative-acute-kidney-injury-results-from-double-blind-randomised-controlled-trial
#6
JOURNAL ARTICLE
Staffan Svenmarker, Helena Claesson Lingehall, Gunnar Malmqvist, Micael Appelblad
INTRODUCTION: The study objective was to investigate whether a Ringer's acetate based priming solution with addition of Mannitol and sodium concentrate increases the risk of cardiac surgery associated kidney injury (CSA-AKI). METHODS: This is a double blind, prospective randomized controlled trial from a single tertiary teaching hospital in Sweden including patients aged ≥65 years ( n = 195) admitted for routine cardiac surgery with cardiopulmonary bypass...
March 21, 2024: Perfusion
https://read.qxmd.com/read/38509318/mechanical-purification-of-lipofilling-the-relationship-between-cell-yield-cell-growth-and-fat-volume-maintenance
#7
JOURNAL ARTICLE
Pietro Gentile, Riccardo Ossanna, Lindsey Alejandra Quintero Sierra, Andrea Sbarbati
BACKGROUND: The mechanical manipulations of fat tissue represented from centrifugation, filtration, washing, and fragmentation were considered the most effective strategies aiming to obtain purified lipofilling with different impacts both in terms of adipose-derived stem cells amount contained in stromal vascular fraction, and fat volume maintenance. OBJECTIVES: The present work aimed to report results in fat volume maintenance obtained by lipofilling purification based on the combined use of washing and filtration, in a clinical study, and to deeply investigate the adipose-derived stem cells yield and growth capacity of the different stromal vascular fraction extraction techniques with an in vitro approach...
March 20, 2024: Aesthetic Plastic Surgery
https://read.qxmd.com/read/38504964/assessing-the-efficacy-of-the-paul-glaucoma-implant-in-pseudoexfoliative-glaucoma
#8
JOURNAL ARTICLE
Ali Olgun, Murat Karapapak
OBJECTIVES: The aim of the study was to evaluate the outcomes and complications associated with PAUL glaucoma implant (PGI) surgery in pseudoexfoliation glaucoma (PXG) patients, comparing them with a primary open-angle glaucoma (POAG) control group. METHODS: A retrospective analysis included 39 PXG and 29 POAG eyes undergoing PGI surgery between January 2020 and December 2022. Surgical success was defined as intraocular pressure (IOP) between ≤21 and ≥6 mmHg at 12 months and no loss of light perception...
2024: Beyoglu eye journal
https://read.qxmd.com/read/38501573/sex-differences-in-outcomes-after-revascularization-for-acute-lower-limb-ischemia-propensity-score-adjusted-analysis
#9
JOURNAL ARTICLE
Emil Karonen, Frida Eek, Talha Butt, Stefan Acosta
BACKGROUND: Previous reports have suggested higher rates of mortality and amputation for female patients in acute lower limb ischemia (ALI). The aims of the present study were to investigate if there is a difference in mortality, amputation, and fasciotomy between the sexes. METHODS: A retrospective cohort study of consecutive patients undergoing index revascularization for ALI between 2001 and 2018 was conducted. A propensity score was created through a logistic regression with female/male sex as an outcome...
March 2024: World Journal of Surgery
https://read.qxmd.com/read/38500054/oxalate-nephropathy-after-pancreaticoduodenectomy-a-case-report
#10
JOURNAL ARTICLE
Claire Barani, Selda Aydin, Nathalie Demoulin, Michel Jadoul
A 75-year-old male developed acute kidney injury KDIGO stage 3 a few weeks after Whipple surgery was performed for a distal cholangiocarcinoma. Kidney biopsy revealed oxalate nephropathy. This was attributed to post-Whipple malabsorption, poor compliance with pancreatic enzyme replacement therapy, and daily intake of vitamin C supplements. Pancreatic enzyme replacement therapy was resumed and calcium carbonate initiated, with an improvement in glomerular filtration rate. Unfortunately, due to oncological progression, best supportive care was initiated...
March 18, 2024: BMC Nephrology
https://read.qxmd.com/read/38497685/incidence-and-risk-factors-of-acute-kidney-injury-after-transcatheter-aortic%C3%A2-valve-replacement
#11
JOURNAL ARTICLE
Zhenjian Xu, Xin Zhou, Hui Yang, Qiuju Chen, Guangxuan Luo, Shichun Cai, Anping Xu
PURPOSE: Acute kidney injury (AKI) is a common early complication secondary to transcatheter aortic valve replacement (TAVR). Studies on the incidence and risk factors for AKI after TAVR surgery are limited to date. Here, we retrospectively analyzed the incidence and risk factors for AKI after TAVR surgery in our hospital. MATERIALS AND METHODS: Patients who underwent TAVR surgery at our hospital from November 2017 to February 2023 were selected. AKI was defined using the 2012 KDIGO definition and staging criteria...
March 18, 2024: Clinical Nephrology
https://read.qxmd.com/read/38486367/clinical-impact-of-the-kidney-failure-risk-equation-for-vascular-access-planning
#12
JOURNAL ARTICLE
Ulrika Hahn Lundström, Chava L Ramspek, Friedo W Dekker, Merel van Diepen, Juan Jesus Carrero, Ulf Hedin, Marie Evans
BACKGROUND: Risk-based thresholds for arteriovenous (AV) access creation has been proposed to aid vascular access planning. We aimed to assess the clinical impact of implementing the kidney failure risk equation (KFRE) for vascular access referral. METHODS: 16,102 nephrology-referred chronic kidney disease (CKD) patients from the Swedish Renal Registry 2008-2018 were included. The KFRE was calculated repeatedly, and the timing was identified for when the KFRE risk exceeded several pre-defined thresholds and/or the estimated glomerular filtration rate <15 ml/min/1...
March 14, 2024: Nephrology, Dialysis, Transplantation
https://read.qxmd.com/read/38464841/non-coronary-atherosclerosis-a-marker-of-poor-prognosis-in-patients-undergoing-coronary-artery-bypass-surgery
#13
JOURNAL ARTICLE
Óscar González-Lorenzo, Juan A Franco Pelaez, Andrea Kallmeyer, Luis Nieto, Laura Esteban, Ana Pello, Álvaro Aceña, Gonzalo Aldamiz, José Tuñón
INTRODUCTION: The presence of non-coronary atherosclerosis (NCA) in patients with coronary artery disease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronary artery bypass grafting (CABG). MATERIALS AND METHODS: This is an observational study involving 567 consecutive patients who underwent CABG. Variables and prognosis were analysed based on the presence or absence of NCA, defined as previous stroke, transient ischaemic attack (TIA), or peripheral artery disease (PAD) [lower extremity artery disease (LEAD), carotid disease, previous lower limb vascular surgery, or abdominal aortic aneurysm (AAA)]...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38463588/dysregulation-of-kidney-proteases-in-the-pathogenesis-of-hypertension-following-unilateral-nephrectomy-in-juvenile-mice
#14
JOURNAL ARTICLE
Rasha Aly, Yunus E Dogan, Niharika Bala, Carlos Lugo, Seena Darwish, Lawrence Shoemaker, Abdel A Alli
BACKGROUND: Unliteral nephrectomy (UNX) results in the reduction of kidney mass. The remaining kidney undergoes compensatory renal growth via hypertrophy of the glomeruli and renal tubules to maintain a normal glomerular filtration rate (GFR). These compensatory mechanisms result in increased capillary pressure and glomerular hyperfiltration to increase single nephron GFR. Over time, hyperfiltration may lead to kidney scarring and the development of hypertension. OBJECTIVES: The first objective of this study was to test the hypothesis that a 50% reduction in functioning nephrons in juvenile mice leads to increased blood pressure over a 24-hour phase...
2024: American Journal of Translational Research
https://read.qxmd.com/read/38459950/microbial-analysis-in-chronic-rhinosinusitis-patients-with-chronic-kidney-disease-and-end-stage-renal-disease
#15
JOURNAL ARTICLE
Sheng-Wei Lo, Meng-Chang Ding, Yao-Te Tsai, Ming-Shao Tsai, Chia-Yen Liu, Cheng-Ming Hsu, Yao-Hsu Yang, Geng-He Chang
INTRODUCTION: This study aimed to elucidate the bacterial profile of chronic rhinosinusitis (CRS) in patients with end-stage renal disease (ESRD) and chronic kidney disease (CKD) compared with nonrenal patients, guiding antibiotic selection for clinicians. METHODS: We retrospectively analyzed 13,906 inpatients from the Chang Gung Research Database who underwent sinus surgery (2004-2018). Patients were categorized into ESRD-CRS, CKD-CRS, and non-CKD-CRS based on the estimated glomerular filtration rate...
March 9, 2024: Laryngoscope
https://read.qxmd.com/read/38454171/comparison-of-intraocular-pressure-profiles-during-the-water-drinking-test-and-the-modified-diurnal-tension-curve
#16
JOURNAL ARTICLE
Timothy E Yap, Yuan Gao, Hanif Ahmad, Fernanda Susanna, Remo Susanna, Eduardo M Normando, Philip A Bloom, Maria Francesca Cordeiro
OBJECTIVES: To compare intraocular pressure (IOP) during the water drinking test (WDT) and modified diurnal tension curve (mDTC) in open-angle glaucoma (OAG) patients, using multimodal, observer-masked tonometry. METHODS: Open-angle glaucoma subjects were prospectively enroled, excluding those who had undergone glaucoma filtration or laser surgery. Two-hourly mDTC Goldmann applanation (GAT) and rebound tonometry (RT) was performed between 8:00 and 16:00, and every 15 min for 45 min after ingestion of 800mls of water...
March 7, 2024: Eye
https://read.qxmd.com/read/38447194/trends-and-outcomes-of-heart-transplantation-in-adults-with-congenital-heart-disease
#17
JOURNAL ARTICLE
Bahaaldin Alsoufi, Deborah Kozik, Melissa Perrotta, Sarah Wilkens, Andrea Nicole Lambert, Shriprassad Deshpande, Mark Slaughter, Jaimin Trivedi
OBJECTIVE: Heart transplantation for adult congenital heart disease is complicated and associated with challenging pretransplant support, long waiting, and high early post-transplant mortality. We explored if surgical and medical advances, and allocation system changes have affected outcomes. METHODS: From United Network for Organ Sharing database, adults with congenital heart disease listed for heart transplantation were queried. To explore practice and outcome trends, patients were divided into 4 eras (eras1-3: nearly 3 equal periods from 1992-2018, era-4: after 2018, corresponding with new allocation system)...
March 6, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38445499/prognostic-implication-of-residual-inflammatory-trajectories-in-acute-type-i-aortic-dissection-dual-center-prospective-cohort-study
#18
JOURNAL ARTICLE
Hong Liu, Yi-Fei Diao, Si-Chong Qian, Yong Feng Shao, Zhi-Hua Zeng, Guo-Liang Fan, Lu-Yao Ma, Hong-Jia Zhang
BACKGROUND: Peripheral platelet-white blood cell ratio (PWR) integrating systemic inflammatory and coagulopathic pathways is a key residual inflammatory measurement in the management of acute DeBakey type I aortic dissection (AAD); however, trajectories of PWR in AAD is poorly defined. METHODS: Two AAD cohorts were included in two cardiovascular centers (2020-2022) if patients underwent emergency total arch replacement with frozen elephant trunk implantation. PWR data were collected over time at baseline and five consecutive days after surgery...
March 4, 2024: International Journal of Surgery
https://read.qxmd.com/read/38441829/impact-of-chronic-kidney-disease-stages-on-surgical-and-functional-outcomes-in-robot-assisted-partial-nephrectomy-for-localized-renal-tumors
#19
JOURNAL ARTICLE
Hiroki Ito, Kentaro Muraoka, Koichi Uemura, Ryosuke Jikuya, Takuya Kondo, Tomoyuki Tatenuma, Takashi Kawahara, Mitsuru Komeya, Yusuke Ito, Hisashi Hasumi, Kazuhide Makiyama
The influence of chronic kidney disease stage on robot-assisted partial nephrectomy outcomes remains underexplored. This study aimed to assess the impact of chronic kidney disease stage on functional and surgical outcomes of robot-assisted partial nephrectomy and identify preoperative predictors of significant postoperative 1-year renal-function loss (RFL). Clinical data of 408 patients who underwent robot-assisted partial nephrectomy at Yokohama City University Hospital between 2016 and 2023 were retrospectively reviewed...
March 5, 2024: Journal of Robotic Surgery
https://read.qxmd.com/read/38440591/central-auditory-processing-impairment-in-renal-failure
#20
JOURNAL ARTICLE
Seyede Faranak Emami, Hossein Emad Momtaz, Mobina Mehrabifard
UNLABELLED: This study is the first to investigate central auditory processing impairment in patients with slight decrease in renal function (PSR), who had no risk factors, evidence of renal injury, and albuminuria. The aim was to determine the scores of dichotic digits test (DDT) and word-in-noise perception (WINP) test in PSR. The survey was cross-sectional-comparative. The case group consisted of 30 PSR, with an estimated glomerular filtration rate of 60-90 mL/min at 1.73 m2. The control group consisted of 60 normal participants...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
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