keyword
https://read.qxmd.com/read/38466758/research-on-surface-treatment-technology-for-quickly-improving-the-skid-resistance-of-tunnel-concrete-pavement
#21
JOURNAL ARTICLE
Jun'an Lei, Fujing Zhao, Yuanyuan Wang, Xiaofeng Ren
In order to solve the problem that the skid resistance of concrete pavement in tunnel deteriorates rapidly, which is easy to cause traffic accidents, the anti-skid rapid elevation technology of surface treatment is proposed. Wear tests were used to investigate the effects of concrete surface roughness, properties of modified emulsified asphalt binder and anti-skid fine aggregate type on long-term skid resistance of treated surfaces. The results show that the four coarsening methods of fine milling, milling, grooving and brooming can improve the skid resistance of concrete, and the skid resistance durability of fine milling and milling is better...
2024: PloS One
https://read.qxmd.com/read/38459819/the-latest-insights-into-rare-blood-disorders-diagnosis-and-treatment-strategies
#22
REVIEW
David J Kuter, Spero R Cataland, Catherine M Broome, Cindy Neunert
Because immune-mediated rare blood disorders are uncommon, healthcare providers often lack the knowledge and experience necessary to identify, diagnose, and treat them in accordance with best practices. As a result, there are significant gaps in care, including delays in diagnosis and suboptimal treatment. To ensure that more patients with these rare disorders are offered quality, evidence-based care, it is essential that healthcare providers possess up-to-date information about best practices and new developments in this area of medicine...
March 9, 2024: American Journal of Hematology
https://read.qxmd.com/read/38455342/a-rare-case-of-advanced-stage-small-cell-carcinoma-of-the-ovary-identified-during-the-third-trimester-of-pregnancy
#23
Lua Saylany, Hasthika Ellepola, Elisha Broom
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare form of aggressive ovarian malignancy linked with mutations in the SMARCA4 gene. This disease predominantly affects young women within the first five decades of life and is associated with poor overall long-term survival, particularly when diagnosed in the advanced stage of the disease. Due to the low incidence of the condition and limited literature, current clinical decision-making is based on a small number of case series and case reports...
March 2024: Curēus
https://read.qxmd.com/read/38451304/accelerating-medicines-partnership%C3%A2-schizophrenia-amp%C3%A2-scz-rationale-and-study-design-of-the-largest-global-prospective-cohort-study-of-clinical-high-risk-for-psychosis
#24
JOURNAL ARTICLE
Cassandra M J Wannan, Barnaby Nelson, Jean Addington, Kelly Allott, Alan Anticevic, Celso Arango, Justin T Baker, Carrie E Bearden, Tashrif Billah, Sylvain Bouix, Matthew R Broome, Kate Buccilli, Kristin S Cadenhead, Monica E Calkins, Tyrone D Cannon, Guillermo Cecci, Eric Yu Hai Chen, Kang Ik K Cho, Jimmy Choi, Scott R Clark, Michael J Coleman, Philippe Conus, Cheryl M Corcoran, Barbara A Cornblatt, Covadonga M Diaz-Caneja, Dominic Dwyer, Bjørn H Ebdrup, Lauren M Ellman, Paolo Fusar-Poli, Liliana Galindo, Pablo A Gaspar, Carla Gerber, Louise Birkedal Glenthøj, Robert Glynn, Michael P Harms, Leslie E Horton, René S Kahn, Joseph Kambeitz, Lana Kambeitz-Ilankovic, John M Kane, Tina Kapur, Matcheri S Keshavan, Sung-Wan Kim, Nikolaos Koutsouleris, Marek Kubicki, Jun Soo Kwon, Kerstin Langbein, Kathryn E Lewandowski, Gregory A Light, Daniel Mamah, Patricia J Marcy, Daniel H Mathalon, Patrick D McGorry, Vijay A Mittal, Merete Nordentoft, Angela Nunez, Ofer Pasternak, Godfrey D Pearlson, Jesus Perez, Diana O Perkins, Albert R Powers, David R Roalf, Fred W Sabb, Jason Schiffman, Jai L Shah, Stefan Smesny, Jessica Spark, William S Stone, Gregory P Strauss, Zailyn Tamayo, John Torous, Rachel Upthegrove, Mark Vangel, Swapna Verma, Jijun Wang, Inge Winter-van Rossum, Daniel H Wolf, Phillip Wolff, Stephen J Wood, Alison R Yung, Carla Agurto, Mario Alvarez-Jimenez, Paul Amminger, Marco Armando, Ameneh Asgari-Targhi, John Cahill, Ricardo E Carrión, Eduardo Castro, Suheyla Cetin-Karayumak, M Mallar Chakravarty, Youngsun T Cho, David Cotter, Simon D'Alfonso, Michaela Ennis, Shreyas Fadnavis, Clara Fonteneau, Caroline Gao, Tina Gupta, Raquel E Gur, Ruben C Gur, Holly K Hamilton, Gil D Hoftman, Grace R Jacobs, Johanna Jarcho, Jie Lisa Ji, Christian G Kohler, Paris Alexandros Lalousis, Suzie Lavoie, Martin Lepage, Einat Liebenthal, Josh Mervis, Vishnu Murty, Spero C Nicholas, Lipeng Ning, Nora Penzel, Russell Poldrack, Pablo Polosecki, Danielle N Pratt, Rachel Rabin, Habiballah Rahimi Eichi, Yogesh Rathi, Avraham Reichenberg, Jenna Reinen, Jack Rogers, Bernalyn Ruiz-Yu, Isabelle Scott, Johanna Seitz-Holland, Vinod H Srihari, Agrima Srivastava, Andrew Thompson, Bruce I Turetsky, Barbara C Walsh, Thomas Whitford, Johanna T W Wigman, Beier Yao, Hok Pan Yuen, Uzair Ahmed, Andrew Jin Soo Byun, Yoonho Chung, Kim Do, Larry Hendricks, Kevin Huynh, Clark Jeffries, Erlend Lane, Carsten Langholm, Eric Lin, Valentina Mantua, Gennarina Santorelli, Kosha Ruparel, Eirini Zoupou, Tatiana Adasme, Lauren Addamo, Laura Adery, Munaza Ali, Andrea Auther, Samantha Aversa, Seon-Hwa Baek, Kelly Bates, Alyssa Bathery, Johanna M M Bayer, Rebecca Beedham, Zarina Bilgrami, Sonia Birch, Ilaria Bonoldi, Owen Borders, Renato Borgatti, Lisa Brown, Alejandro Bruna, Holly Carrington, Rolando I Castillo-Passi, Justine Chen, Nicholas Cheng, Ann Ee Ching, Chloe Clifford, Beau-Luke Colton, Pamela Contreras, Sebastián Corral, Stefano Damiani, Monica Done, Andrés Estradé, Brandon Asika Etuka, Melanie Formica, Rachel Furlan, Mia Geljic, Carmela Germano, Ruth Getachew, Mathias Goncalves, Anastasia Haidar, Jessica Hartmann, Anna Jo, Omar John, Sarah Kerins, Melissa Kerr, Irena Kesselring, Honey Kim, Nicholas Kim, Kyle Kinney, Marija Krcmar, Elana Kotler, Melanie Lafanechere, Clarice Lee, Joshua Llerena, Christopher Markiewicz, Priya Matnejl, Alejandro Maturana, Aissata Mavambu, Rocío Mayol-Troncoso, Amelia McDonnell, Alessia McGowan, Danielle McLaughlin, Rebecca McIlhenny, Brittany McQueen, Yohannes Mebrahtu, Martina Mensi, Christy Lai Ming Hui, Yi Nam Suen, Stephanie Ming Yin Wong, Neal Morrell, Mariam Omar, Alice Partridge, Christina Phassouliotis, Anna Pichiecchio, Pierluigi Politi, Christian Porter, Umberto Provenzani, Nicholas Prunier, Jasmine Raj, Susan Ray, Victoria Rayner, Manuel Reyes, Kate Reynolds, Sage Rush, Cesar Salinas, Jashmina Shetty, Callum Snowball, Sophie Tod, Gabriel Turra-Fariña, Daniela Valle, Simone Veale, Sarah Whitson, Alana Wickham, Sarah Youn, Francisco Zamorano, Elissa Zavaglia, Jamie Zinberg, Scott W Woods, Martha E Shenton
This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the development and use of novel pharmacological interventions for CHR individuals. We present a description of the participating research networks and the data processing analysis and coordination center, their processes for data harmonization across 43 sites from 13 participating countries (recruitment across North America, Australia, Europe, Asia, and South America), data flow and quality assessment processes, data analyses, and the transfer of data to the National Institute of Mental Health (NIMH) Data Archive (NDA) for use by the research community...
March 7, 2024: Schizophrenia Bulletin
https://read.qxmd.com/read/38425725/a-case-report-of-heterozygous-familial-hypercholesterolaemia-with-ldlr-gene-mutation-complicated-by-premature-coronary-artery-disease-detected-in-primary-care
#25
Mohamad Abu Zar Abdul-Halim, Hasidah Abdul-Hamid, Noorhida Baharudin, Mohamed-Syarif Mohamed-Yassin, Sazzli Shahlan Kasim, Hapizah Nawawi, Nadeem Qureshi, Anis Safura Ramli
BACKGROUND: Familial hypercholesterolaemia (FH) is an autosomal dominant genetic condition predominantly caused by the low-density lipoprotein receptor ( LDLR ) gene mutation. CASE SUMMARY: This is the case of a 54-year-old Malay woman with genetically confirmed FH complicated by premature coronary artery disease (PCAD). She was clinically diagnosed in primary care at 52 years old, fulfilling the Simon Broome Criteria (possible FH), Dutch Lipid Clinic Criteria (score of 8: probable FH), and Familial Hypercholesterolaemia Case Ascertainment Tool (relative risk score of 9...
February 2024: European Heart Journal. Case Reports
https://read.qxmd.com/read/38419235/knowledge-attitude-and-practice-of-physicians-towards-familial-hypercholesterolaemia-in-north-regions-of-saudi-arabia
#26
JOURNAL ARTICLE
Aseel Awad Alsaidan
OBJECTIVE: To assess knowledge, attitude and practice of physicians regarding familial hypercholesterolaemia. METHODS: The cross-sectional study was conducted from October to December 2022 in Aljouf, Tabouk, Hail and northern border regions of Saudi Arabia after approval from the ethics review committee of Qurayyat Health Affairs. Those included were physicians specialising in familial hypercholesterolaemia and having experience in family medicine, endocrinology, paediatrics, cardiology, internal medicine and obstetrics and gynaecology...
February 2024: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/38411606/occurrence-of-praxelis-clematidea-witches-broom-disease-association-with-16sri-group-candidatus-phytoplasma-asteris-in-hainan-island-of-china
#27
JOURNAL ARTICLE
Shao-Shuai Yu, Chuan-Sheng Song, Wei-Wei Song
Praxelis clematidea is an invasive herbaceous plant belonging to Asteraceae family. From August to November 2020, the plants showing severe witches'-broom symptoms were found in farms and roadsides from Ding'an of Hainan Province, a tropical island of China. The disease symptoms were suggestive of phytoplasma infection. For pathogen detection, P. clematidea samples consisting of six symptomatic and three asymptomatic plants were collected from the farms and roadsites of Ding'an with 40 % incidence by conducting surveys and statistics...
February 27, 2024: Plant Disease
https://read.qxmd.com/read/38397102/comprehensive-analysis-of-the-gras-gene-family-in-paulownia-fortunei-and-the-response-of-della-proteins-to-paulownia-witches-broom
#28
JOURNAL ARTICLE
Yixiao Li, Yabing Cao, Yujie Fan, Guoqiang Fan
The GRAS (GAI\RGA\SCL) gene family encodes plant-specific transcription factors that play crucial roles in plant growth and development, stress tolerance, and hormone network regulation. Plant dwarfing symptom is mainly regulated by DELLA proteins of the GRAS gene subfamily. In this study, the association between the GRAS gene family and Paulownia witches' broom (PaWB) was investigated. A total of 79 PfGRAS genes were identified using bioinformatics methods and categorized into 11 groups based on amino acid sequences...
February 19, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38396939/genome-wide-identification-of-the-paulownia-fortunei-aux-iaa-gene-family-and-its-response-to-witches-broom-caused-by-phytoplasma
#29
JOURNAL ARTICLE
Jiaming Fan, Minjie Deng, Bingbing Li, Guoqiang Fan
The typical symptom of Paulownia witches' broom (PaWB), caused by phytoplasma infection, is excessive branching, which is mainly triggered by auxin metabolism disorder. Aux/IAA is the early auxin-responsive gene that participates in regulating plant morphogenesis such as apical dominance, stem elongation, lateral branch development, and lateral root formation. However, no studies have investigated the response of the Aux/IAA gene family to phytoplasma infection in Paulownia fortunei . In this study, a total of 62 Aux/IAA genes were found in the genome...
February 13, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38393681/phytoplasma-a-plant-pathogen-that-cannot-be-ignored-in-agricultural-production-research-progress-and-outlook
#30
REVIEW
Ruotong Wang, Bixin Bai, Danyang Li, Jingke Wang, Weijie Huang, Yunfeng Wu, Lei Zhao
Phytoplasmas are phloem-restricted plant-pathogenic bacteria transmitted by insects. They cause diseases in a wide range of host plants, resulting in significant economic and ecological losses worldwide. Research on phytoplasmas has a long history, with significant progress being made in the past 30 years. Notably, with the rapid development of phytoplasma research, scientists have identified the primary agents involved in phytoplasma transmission, established classification and detection systems for phytoplasmas, and 243 genomes have been sequenced and assembled completely or to draft quality...
February 2024: Molecular Plant Pathology
https://read.qxmd.com/read/38390906/long-term-effects-of-neuraxial-analgesia
#31
JOURNAL ARTICLE
Rachel J Kearns, Malcolm A Broom, Dominique N Lucas
PURPOSE OF REVIEW: This review article explores the potential longer-term implications of neuraxial analgesia in labour for both the mother and her child. RECENT FINDINGS: Neuraxial techniques for labour analgesia are well tolerated and effective, and long-term adverse sequelae are rare. Labour epidural analgesia is not independently associated with long-term headache, backache, postnatal depression or anal sphincter injury, and evidence supports that epidurals may offer protection against severe maternal morbidity, particularly in women at a higher risk of complications...
February 22, 2024: Current Opinion in Anaesthesiology
https://read.qxmd.com/read/38379222/first-report-of-candidatus-phytoplasma-citri-related-strain-16srii-c-subgroup-associated-with-phyllody-disease-of-cumin-in-india
#32
JOURNAL ARTICLE
Manish Kumar, Kartar Singh, Motilal Mehriya, Surabhi Mitra, Priyam Panda, Neelam Shekhawat, Vijay Singh Meena, Govind P Rao
Cumin (Cuminum cyminum L.), is an important export-oriented seed spice crop for India. Cumin is popularly used for flavouring food, including soups, pickles and vegetables, and for herbal medicine. India is the largest producer, consumer and exporter of cumin seed with an annual production of 0.795 million tones over an area of 1.09 million hectares. During 2020-21, India exported about 0.299 million tons of cumin worth of Rs 33280 million (Anonymous, 2021). Recently, phytoplasma suspected symptoms were observed in cumin at Agricultural Research Station, Mandor, Jodhpur, Rajasthan, India from 2019...
February 20, 2024: Plant Disease
https://read.qxmd.com/read/38372722/-moniliophthora-perniciosa-in-angola-africa-the-first-record-in-the-eastern-hemisphere
#33
JOURNAL ARTICLE
Mary Catherine Aime, Albertina Nzuzi, Thea Lautenschläger
Moniliophthora perniciosa causes a destructive disease known as witches' broom disease of cacao (WBDC). WBDC has been responsible for major reductions in production or even total abandonment of cacao plantations in most countries that it has invaded. To date, however, the disease is known only from the cacao-producing regions of South America, and a few Central American and Caribbean countries. It is not known from the Eastern Hemisphere and remains a major threat should it invade West Africa or Southeast Asia, where the majority of the world's chocolate production now occurs...
February 19, 2024: Plant Disease
https://read.qxmd.com/read/38356355/protecting-and-promoting-editorial-independence
#34
JOURNAL ARTICLE
Kamaldeep Bhui, Aileen O'Brien, Rachel Upthegrove, Alexander C Tsai, Mustafa Soomro, Giles Newton-Howes, Matthew R Broome, Andrew Forrester, Patricia Casey, Anne M Doherty, William Lee, Kenneth R Kaufman
We argue that editorial independence, through robust practice of publication ethics and research integrity, promotes good science and prevents bad science. We elucidate the concept of research integrity, and then discuss the dimensions of editorial independence. Best practice guidelines exist, but compliance with these guidelines varies. Therefore, we make recommendations for protecting and strengthening editorial independence.
February 15, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38350827/validating-the-fitbit-charge-4%C3%A2-wearable-activity-monitor-for-use-in-physical-activity-interventions
#35
JOURNAL ARTICLE
Alexander Waddell, Stefan Birkett, David Broom, Gordon McGregor, Amy E Harwood
OBJECTIVES: Commercially available wearable activity monitors can promote physical activity behaviour. Clinical trials typically quantify physical activity with research grade activity monitors prior to testing interventions utilising commercially available wearable activity monitors aimed at increasing step count. Therefore, it is important to test the agreement of these two types of activity monitors. OBJECTIVES: Observational. METHODS: Thirty adults (20-65 years, n = 19 females) were provided a Fitbit Charge 4©...
January 25, 2024: Journal of Science and Medicine in Sport
https://read.qxmd.com/read/38339771/scoping-review-of-systematic-reviews-of-nursing-interventions-in-a-neonatal-intensive-care-unit-or-special-care-nursery
#36
REVIEW
Jann Foster, Sheeja Perumbil Pathrose, Laura Briguglio, Suza Trajkovski, Patricia Lowe, Renee Muirhead, Jeewan Jyoti, Linda Ng, Nicole Blay, Kaye Spence, Natasha Chetty, Margaret Broom
AIM(S): To identify, synthesise and map systematic reviews of the effectiveness of nursing interventions undertaken in a neonatal intensive care unit or special care nursery. DESIGN: This scoping review was conducted according to the JBI scoping review framework. METHODS: Review included systematic reviews that evaluated any nurse-initiated interventions that were undertaken in an NICU or SCN setting. Studies that reported one or more positive outcomes related to the nursing interventions were only considered for this review...
February 9, 2024: Journal of Clinical Nursing
https://read.qxmd.com/read/38339431/retracted-liu-et-al-prediction-of-ovarian-cancer-response-to-therapy-based-on-deep-learning-analysis-of-histopathology-images-cancers-2023-15-4044
#37
Yuexin Liu, Barrett C Lawson, Xuelin Huang, Bradley M Broom, John N Weinstein
The journal and authors wish to retract the article entitled 'Prediction of Ovarian Cancer Response to Therapy Based on Deep Learning Analysis of Histopathology Images' cited above [...].
January 24, 2024: Cancers
https://read.qxmd.com/read/38322988/structure-basis-for-recognition-of-plant-rpn10-by-phytoplasma-sap05-in-ubiquitin-independent-protein-degradation
#38
JOURNAL ARTICLE
Liying Zhang, Yunxiang Du, Qian Qu, Qingyun Zheng
Besides traditional ubiquitin-dependent proteasome degradation, thousands of eukaryotic proteins more than previously appreciated could undergo ubiquitin-independent proteasomal degradation (UbInPD). A pathogen-encoded effector protein SAP05 secreted by phytoplasma, could hijack hostage Rpn10 subunit of proteasome derived from Arabidopsis thaliana and target the degradation of GATA BINDING FACTOR (GATA) or SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE (SPL) transcription factors (TFs) without ubiquitin or additional proteasome shuttle factors...
February 16, 2024: IScience
https://read.qxmd.com/read/38320293/the-candidatus-phytoplasma-ziziphi-effectors-sjp1-2-negatively-control-leaf-size-by-stabilizing-zjtcp2-in-jujube
#39
JOURNAL ARTICLE
Fuli Ma, Yunyan Zheng, Ning Zhang, Mingsheng Deng, Meiqi Zhao, Gongyu Fu, Junyong Zhou, Chenglong Guo, Yamei Li, Jinqiu Huang, Qibao Sun, Jun Sun
Phytoplasmas manipulate host plant development to benefit their invasion and insect vector colonization. However, the virulence factors and mechanisms underlying small leaf formation caused by jujube witches' broom (JWB) phytoplasmas remain largely unknown. Here, effectors SJP1 and SJP2 from JWB phytoplasmas were identified to induce small leaf formation in jujube. In vivo interaction and expression assays showed that SJP1 and SJP2 interacted with and stabilized ZjTCP2. Over-expression of SJP1 and SJP2 in jujube induced ZjTCP2 accumulation...
February 6, 2024: Journal of Experimental Botany
https://read.qxmd.com/read/38319623/first-report-of-candidatus-phytoplasma-australasiaticum-associated-with-phyllody-virescence-and-witches-broom-disease-in-chrysanthemum-morifolium-in-taiwan
#40
JOURNAL ARTICLE
Yi-Wen Tseng, Chung Jan Chang, Fuh-Jyh Jan
Chrysanthemum morifolium (Asteraceae) is commonly grown as commercial cut flowers or pot mums worldwide. Common diseases of chrysanthemum include bacterial blight, fungal diseases, viruses, and phytoplasmas (Verma et al. 2003; Taloh et al. 2020). In June 2022, C. morifolium plants showing virescence, stunting, witches' broom, and phyllody symptoms were observed in 10 plants representing 10% of the estimated 100 plants in a field in Taichung City, Taiwan (Fig. S1). Three symptomatic samples along with three asymptomatic ones were collected for further study...
February 6, 2024: Plant Disease
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