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https://www.readbyqxmd.com/read/28917679/epidemiology-of-left-ventricular-systolic%C3%A2-dysfunction-and-heart-failure-in%C3%A2-the-framingham-study-an-echocardiographic-study-over-3-decades
#1
Ramachandran S Vasan, Vanessa Xanthakis, Asya Lyass, Charlotte Andersson, Connie Tsao, Susan Cheng, Jayashri Aragam, Emelia J Benjamin, Martin G Larson
OBJECTIVES: The purpose of this study was to describe the temporal trends in prevalence of left ventricular systolic dysfunction (LVSD) in individuals without and with heart failure (HF) in the community over a 3-decade period of observation. BACKGROUND: Temporal trends in the prevalence and management of major risk factors may affect the epidemiology of HF. METHODS: We compared the frequency, correlates, and prognosis of LVSD (left ventricular ejection fraction [LVEF] <50%) among Framingham Study participants without and with clinical HF in 3 decades (1985 to 1994, 1995 to 2004, and 2005 to 2014)...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28917302/the-global-seroprevalence-of-toxoplasma-gondii-among-wild-boars-a-systematic-review-and-meta-analysis
#2
Ali Rostami, Seyed Mohammad Riahi, Yadollah Fakhri, Vafa Saber, Hooman Hanifehpour, Soghra Valizadeh, Majid Gholizadeh, Rokhsane Hosseini Pouya, H Ray Gamble
This systematic review and meta-analysis study was performed to evaluate the worldwide seroprevalence of Toxoplasma gondii among wild boar. We searched PubMed, Science Direct, Web of Science, Cochrane, Scopus, EBSCOhost and Google Scholar databases for studies reporting T. gondii seroprevalence in wild boars between January 1995 and March 2017. Inclusion and exclusion criteria were applied. We estimated the pooled seroprevalence of T. gondii in wild boars using a random-effects model, and evaluated overall seroprevalence in different geographical areas...
September 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28917222/validation-of-summer-and-winter-elisa-measurements-of-serum-25-hydroxyvitamin-d-concentrations-in-mongolia
#3
Sabri Bromage, Daria Tselmen, Gary Bradwin, Michael F Holick, Davaasaambuu Ganmaa
BACKGROUND AND OBJECTIVES: Assay cost, quality, and availability pose challenges for vitamin D surveys in limited resource settings. This study aimed to validate an inexpensive vitamin D assay (ELISA) under real-world conditions in Mongolia, the northernmost developing country, to characterize the assay's usefulness and inform the design of epidemiologic studies in similar regions. METHODS AND STUDY DESIGN: We collected paired summer and winter serum samples from 120 men and women (aged 20-57 years) in urban and rural Mongolia, analyzed each sample for 25(OH)D concentration using both Immunodiagnostic Systems ELISA and DiaSorin LIAISON 25(OH)D TOTAL, and compared the assays using multiple statistics...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28917005/outcome-of-pediatric-acute-kidney-injury-a-multicenter-prospective-cohort-study
#4
Jameela A Kari, Khalid A Alhasan, Mohamed A Shalaby, Norah Khathlan, Osama Y Safdar, Suleman A Al Rezgan, Sherif El Desoky, Amr S Albanna
BACKGROUND: Acute kidney injury (AKI) is a common problem encountered in critically ill children with an increasing incidence and evolving epidemiology. AKI carries a serious morbidity and mortality in patients requiring admission to a pediatric intensive care unit (PICU). METHODS: We undertook a prospective cohort study of PICU admissions at three tertiary care hospitals in the Kingdom of Saudi Arabia over 2 years. The Kidney Disease Improving Global Outcomes (KDIGO) definition was used to diagnose AKI...
September 15, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28916937/the-conversion-of-exposures-due-to-radon-into-the-effective-dose-the-epidemiological-approach
#5
T R Beck
The risks and dose conversion coefficients for residential and occupational exposures due to radon were determined with applying the epidemiological risk models to ICRP representative populations. The dose conversion coefficient for residential radon was estimated with a value of 1.6 mSv year(-1) per 100 Bq m(-3) (3.6 mSv per WLM), which is significantly lower than the corresponding value derived from the biokinetic and dosimetric models. The dose conversion coefficient for occupational exposures with applying the risk models for miners was estimated with a value of 14 mSv per WLM, which is in good accordance with the results of the dosimetric models...
September 15, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28916903/merkel-cell-carcinoma-epidemiology-pathogenesis-diagnosis-and-therapy
#6
REVIEW
Teresa Amaral, Ulrike Leiter, Claus Garbe
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with a neuroendocrine phenotype. Incidence varies according to the geographic regions but is overall increasing. Different risk factors have been identified namely advanced age, immunosuppression, and ultraviolet light exposure. An association between MCC and polyomavirus infection is known. However, the exact mechanism that leads to carcinogenesis is yet to be fully understood. Surgery when feasible is the recommended treatment for localized disease, followed by adjuvant radiation or chemoradiation...
September 16, 2017: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/28916132/the-association-between-elevated-blood-lead-levels-and-violent-behavior-during-late-adolescence-the-south-african-birth-to-twenty-plus-cohort
#7
Palesa Nkomo, Angela Mathee, Nisha Naicker, Jacky Galpin, Linda M Richter, Shane A Norris
Epidemiological studies have shown the adverse neuro-behavioral health effects of lead exposure among children, in particular. However, there is lack evidence in this regard from developing countries. The main aim of this study was to assess the association between blood lead levels (BLLs) during early adolescence and violent behavior in late adolescence. Our study sample from the Birth to Twenty Plus cohort in Soweto-Johannesburg, South Africa included 1332 study participants (684 females). BLLs were measured using blood samples collected at age 13years...
September 12, 2017: Environment International
https://www.readbyqxmd.com/read/28915886/prognostic-factors-in-patients-with-loco-regionally-advanced-gastric-cancer
#8
Bo Hultman, Ulf Gunnarsson, Peter Nygren, Magnus Sundbom, Bengt Glimelius, Haile Mahteme
BACKGROUND: The aim of this study was to investigate epidemiologic and prognostic factors relevant to the treatment of loco-regionally advanced gastric cancer (GC). METHODS: Two hundred and fifty-five patients with GC were identified in Uppsala County between 2000 and 2009. Patient records were analyzed for loco-regionally advanced GC defined as tumor with peritoneal involvement, excluding serosal invasion from the primary tumor only, at primary diagnosis or during follow-up...
September 15, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28915849/exposure-rate-of-vzv-among-women-attending-antenatal-care-clinic-in-sri-lanka-a-cross-sectional-study
#9
Saluwadana Walawwe Pavithra Lakmini Daulagala, Faseeha Noordeen, Mohamed Mukthar Fathina Fara, Chathura Rathnayake, Kapila Gunawardana
BACKGROUND: Varicella or chickenpox was not a notifiable disease until 2005 in Sri Lanka and only a few studies have been conducted on the epidemiology of VZV infection in the country. The anti-VZV IgG sero-prevalence among antenatal women is extremely limited and thus a selected group of antenatal clinic attendees were chosen to determine the exposure rate to VZV infection. METHODS: Women attending the antenatal clinic at Teaching Hospital, Peradeniya, Sri Lanka were selected for the study and 3 mL of venous blood was collected from 181 participants and the demographic data was obtained through a pre-tested questionnaire...
September 16, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28915839/risk-of-mortality-among-children-adolescents-and-adults-with-autism-spectrum-disorder-or-attention-deficit-hyperactivity-disorder-and-their-first-degree-relatives-a-protocol-for-a-systematic-review-and-meta-analysis-of-observational-studies
#10
Ferrán Catalá-López, Brian Hutton, Matthew J Page, Manuel Ridao, Jane A Driver, Adolfo Alonso-Arroyo, Jaume Forés-Martos, Diego Macías Saint-Gerons, Eduard Vieta, Alfonso Valencia, Rafael Tabarés-Seisdedos
BACKGROUND: Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are childhood onset neurodevelopmental disorders that may persist into adulthood. ASD and ADHD tend to run in families and may have a significant negative impact on the health and longevity of those with the disorder and their relatives. The aim of this study will be to analyze the risk of mortality among children, adolescents, and adults with ASD or ADHD and their first-degree relatives. METHODS/DESIGN: We will conduct a systematic review and meta-analysis of observational studies...
September 15, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28915823/patients-with-acute-poisoning-presenting-to-an-urban-emergency-department-of-a-tertiary-hospital-in-tanzania
#11
Ghaniya S Mbarouk, Hendry R Sawe, Juma A Mfinanga, John Stein, Shankar Levin, Victor Mwafongo, Michael S Runyon, Teri A Reynolds, Kent R Olson
BACKGROUND: Poisoning is a major public health concern in sub-Saharan Africa, affecting patients of all age groups. Poisoned patients often present to the emergency department (ED) and prompt evaluation and appropriate management are imperative to ensure optimal outcomes. Unfortunately, little is known about the specific presentations of poisoned patients in East Africa. We describe the clinical and epidemiological features of patients presenting to the Muhimbili National Hospital (MNH) ED with suspected toxicological syndromes...
September 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28915771/low-back-pain-with-impact-at-17-years-of-age-is-predicted-by-early-adolescent-risk-factors-from-multiple-domains-analysis-of-the-western-australian-pregnancy-cohort-raine-study
#12
Anne Smith, Darren Beales, Peter O'Sullivan, Natasha Bear, Leon Straker
Study Design Prospective cohort study of the Western Australian Pregnancy Cohort (Raine) Study. Background Low back pain (LBP) commonly develops in adolescence and is a significant risk factor for adult LBP. A broad range of factors have been associated with the development of adolescent LBP, but prior literature has limitations related to characterisation of LBP and scope of risk factors considered. Objective This study aimed to identify potential factors contributing to the development of LBP with and without impact at 17 years of age, utilising a broad range of exposures at 14...
September 15, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28915687/features-and-risk-factors-of-carotid-atherosclerosis-in-a-population-with-high-stroke-incidence-in-china
#13
Yanqiu Zhang, Lingling Bai, Min Shi, Hongyan Lu, Yanan Wu, Jun Tu, Jingxian Ni, Jinghua Wang, Li Cao, Ping Lei, Xianjia Ning
Epidemiological studies have reported associations between traditional cardiovascular risk factors and carotid intima-media thickness (CIMT) or carotid plaque. However, definite risk factors at different phases of carotid atherosclerosis remain controversial. We aimed to explore risk factors and characteristics of carotid atherosclerosis at different stages in a low-income population with a high incidence of stroke in China. Between April 2014 and January 2015, we recruited 3789 stroke-free and cardiovascular disease-free residents aged ≥ 45 years...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28915333/air-pollution-and-other-environmental-modulators-of-cardiac-function
#14
Matthew W Gorr, Michael J Falvo, Loren E Wold
Cardiovascular disease (CVD) is the leading cause of death in developed regions and a worldwide health concern. Multiple external causes of CVD are well known, including obesity, diabetes, hyperlipidemia, age, and sedentary behavior. Air pollution has been linked with the development of CVD for decades, though the mechanistic characterization remains unknown. In this comprehensive review, we detail the background and epidemiology of the effects of air pollution and other environmental modulators on the heart, including both short- and long-term consequences...
September 12, 2017: Comprehensive Physiology
https://www.readbyqxmd.com/read/28915302/prevalence-of-gingivitis-in-a-group-of-35-to-70-year-olds-residing-in-puerto-rico
#15
Augusto R Elías-Boneta, Angeliz Encarnación, Sona Rivas-Tumanyan, Beatriz C Berríos-Ouslán, Bayardo García-Godoy, Margarita Murillo, Jomar Diaz-Nicolas, Ferdinand Lugo, Milagros J Toro
OBJECTIVE: Gingivitis, an inflammation of the gingival tissues, typically progresses to periodontitis. The objective of this study is to estimate the prevalence of gingivitis in 35- to 70-year-olds residing in San Juan, Puerto Rico, and assess the differences in gingivitis distribution between age and gender groups. METHODS: A cross-sectional epidemiological study was conducted with a sample of patients from a private practice and patients/employees of the Puerto Rico Medical Center...
September 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28915247/trends-and-correlates-of-cystic-echinococcosis-in-chile-2001-2012
#16
Soledad Colombe, Eri Togami, Fkadu Gelaw, Marina Antillon, Rodrigo Fuentes, Daniel Martin Weinberger
Echinococcosis is a neglected zoonotic disease affecting over 1 million people worldwide at any given time. It is the leading cause of hospital admissions for parasitic diseases in Chile. We conducted a retrospective investigation of hospitalized cases to describe the epidemiological trends of echinococcosis in Chile. We also examined the potential environmental risk factors for echinococcosis hospitalization rates. Through nation-wide hospital discharge data, a total of 11,516 hospitalized patients with cystic echinococcosis were identified between January 2001 and December 2012...
September 15, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28914448/significant-burden-of-nonalcoholic-fatty-liver-disease-with-advanced-fibrosis-in-the-us-a-cross-sectional-analysis-of-2011-2014-national-health-and-nutrition-examination-survey
#17
R J Wong, B Liu, T Bhuket
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease in the US. Understanding the epidemiology of NAFLD, with specific focus on individuals with hepatic fibrosis is important to guide healthcare resource planning. AIM: To evaluate prevalence and predictors of hepatic fibrosis among US adults with NAFLD. METHODS: We performed a cross-sectional study using data from the updated 2011-2014 National Health and Nutrition Examination Survey, a national, stratified, multistage sampling survey of non-institutionalised US adults age ≥ 20...
September 15, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28914352/impact-of-physical-activity-on-reporting-of-childhood-asthma-symptoms
#18
Benedicta Nneoma Nnodum, Meredith C McCormack, Nirupama Putcha, Seungyoung Hwang, Laura M Paulin, Emily P Brigham, Ashraf Fawzy, Karina Romero, Gregory B Diette, Nadia N Hansel
This study aims to determine the impact of physical activity on asthma symptom reporting among children living in an inner city. Among 147 children aged 5-12 years with physician-diagnosed asthma, we assessed asthma symptoms using twice-daily diaries and physical activity using the physical activity questionnaire for children during three 8-day periods (baseline, 3 and 6 months). Linear, logistic, and quasi-poisson regression models were used to determine the association between physical activity and asthma symptoms; adjusting for age, sex, race, BMI, caregiver's education, asthma severity, medication use, and season...
September 15, 2017: Lung
https://www.readbyqxmd.com/read/28914079/co-infection-of-human-herpesvirus-type-2-hhv-2-and-human-immunodeficiency-virus-hiv-among-pregnant-women-in-rio-de-janeiro-brazil
#19
Lyana Rodrigues Pinto Lima, Luis Eduardo Barros Costa Fernandes, Daniel A M Villela, Mariza Gonçalves Morgado, José Henrique Pilotto, Vanessa Salete de Paula
Pregnant women who are infected with the Human Immunodeficiency Virus (HIV) are particularly vulnerable to severe and recurrent infections with Human Herpesvirus 2 (HHV-2). Neonatal transmission of HHV-2 has been associated with malformations and neurological sequelae in infants, which makes it very important to perform antenatal monitoring for genital herpes. In the study, 134 pregnant women infected with HIV were tested for HHV-2 IgM and IgG using an enzyme-linked immunosorbent assay (ELISA) and had HHV-2 DNA analyzed by Real Time Polymerase Chain Reaction (qPCR)...
September 15, 2017: AIDS Care
https://www.readbyqxmd.com/read/28913713/ethnic-groups-differ-in-how-poor-self-rated-mental-health-reflects-psychiatric-disorders
#20
Shervin Assari
AIM: This study aimed to explore cross-ethnic variation in the pattern of the associations between psychiatric disorders and self-rated mental health (SRMH) in the USA. METHODS: This cross-sectional study used data from the Collaborative Psychiatric Epidemiology Surveys (CPES), 2001-2003, a national household probability sample. The study enrolled 18,237 individuals who were either Non-Hispanic White (n = 7587), African American (n = 4746), Mexican (n = 1442), Cuban (n = 577), Puerto Rican (n = 495), Other Hispanic (n = 1106), Vietnamese (n = 520), Filipino (n = 508), Chinese (n = 600) or Other Asian (n = 656)...
September 14, 2017: Journal of Racial and Ethnic Health Disparities
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