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https://www.readbyqxmd.com/read/29346653/emergence-of-acute-subacute-infant-juvenile-paracoccidioidomycosis-in-northeast-argentina-effect-of-climatic-and-anthropogenic-changes
#1
Gustavo Giusiano, Clarisa Aguirre, Claudia Vratnica, Florencia Rojas, Teresa Corallo, María Emilia Cattana, Mariana Fernández, Javier Mussin, María de Los Angeles Sosa
Argentina has two endemic areas of paracoccidioidomycosis (PCM). Bordering Paraguay and Brazil, Northeast Argentina (NEA) comprises the area with the highest incidence where the chronic adult clinical form has historically been reported. Juvenile form in children and adolescents is rare in this area since only one case was reported in the last 10 years. Despite this, between 2010 and 2012, several cases of acute/subacute clinical forms in children aged 10 to 16 (median 12) were detected. In the last decade, the NEA region has been exposed to ecological variations as consequences of certain climatic and anthropogenic changes, including El Niño-Southern Oscillation phenomenon during 2009, and deforestation...
January 13, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29346374/epidemiological-investigation-into-the-prevalence-of-abnormal-inter-arm-blood-pressure-differences-among-different-ethnicities-in-xinjiang-china
#2
Ling Sun, Ting Zou, Bao-Zhu Wang, Fen Liu, Qing-Hua Yuan, Yi-Tong Ma, Xiang Ma
OBJECTIVES: The prevalence of and risk factors for IAD among different ethnicity groups was unknown. Our aim was to investigate the prevalence of and risk factors for IAD among Han, Uygur and Kazakh ethnicities in Xinjiang. China. METHODS: In total, 14,618 adult participants (7,799 males and 6,819 females) were recruited from the Cardiovascular Risk Survey. A 4-stage stratified cluster random sampling method was used. The participants' personal information and medical history were assessed by questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29345684/msh6-and-pms2-germ-line-pathogenic-variants-implicated-in-lynch-syndrome-are-associated-with-breast-cancer
#3
Maegan E Roberts, Sarah A Jackson, Lisa R Susswein, Nur Zeinomar, Xinran Ma, Megan L Marshall, Amy R Stettner, Becky Milewski, Zhixiong Xu, Benjamin D Solomon, Mary Beth Terry, Kathleen S Hruska, Rachel T Klein, Wendy K Chung
PurposeAn association of Lynch syndrome (LS) with breast cancer has been long suspected; however, there have been insufficient data to address this question for each of the LS genes individually.MethodsWe conducted a retrospective review of personal and family history in 423 women with pathogenic or likely pathogenic germ-line variants in MLH1 (N = 65), MSH2 (N = 94), MSH6 (N = 140), or PMS2 (N = 124) identified via clinical multigene hereditary cancer testing. Standard incidence ratios (SIRs) of breast cancer were calculated by comparing breast cancer frequencies in our study population with those in the general population (Surveillance, Epidemiology, and End Results 18 data)...
January 18, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29345408/the-effect-of-eradication-of-helicobacter-pylori-on-gastric-cancer-prevention-in-healthy-asymptomatic-populations
#4
Suh Eun Bae, Kee Don Choi, Jaewon Choe, Seon Ok Kim, Hee Kyong Na, Ji Young Choi, Ji Yong Ahn, Kee Wook Jung, JeongHoon Lee, Do Hoon Kim, Hye-Sook Chang, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
BACKGROUND: Although many epidemiologic studies have evaluated the effect of Helicobacter pylori eradication on gastric cancer, the effect is still uncertain in general populations. We evaluated whether H. pylori eradication would affect the incidence of gastric cancer in healthy asymptomatic populations. MATERIALS AND METHODS: We performed a retrospective cohort study in 38 984 asymptomatic individuals, who underwent health screening examinations more than twice between 2005 and 2016...
January 18, 2018: Helicobacter
https://www.readbyqxmd.com/read/29345125/naturally-acquired-bovine-besnoitiosis-disease-frequency-risk-and-outcome-in-an-endemically-infected-beef-herd
#5
N S Gollnick, J C Scharr, S Schares, A Bärwald, G Schares, M C Langenmayer
The recent spread of bovine besnoitiosis warrants further epidemiological investigations to improve the knowledge on disease development. Thus, a 4-year longitudinal open cohort study was conducted in the first German cattle herd naturally infected with Besnoitia besnoiti. At seven herd-visits between 2008 and 2012, fourteen breeding bulls (>1.5 years) and 131 females (>1 year) were examined clinically and serologically. In females, clinical and serological prevalences, incidence and remission rates were determined...
January 17, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29344824/brucellosis-risk-in-urban-and-agro-pastoral-areas-in-tanzania
#6
Shingo Asakura, George Makingi, Rudovick Kazwala, Kohei Makita
Epidemiology of human and animal brucellosis may depend on ecological conditions. A cross-sectional study was conducted to compare prevalence and risk factors of bovine brucellosis, and risky behaviours for the human infection between urban and agro-pastoral areas in Morogoro region, Tanzania. Cattle blood sampling and interviews using a structured questionnaire were conducted with farmers. Rose-Bengal test was conducted for the cattle sera, and positive samples were confirmed with competitive ELISA. Farm-level sero-prevalences were 0...
January 17, 2018: EcoHealth
https://www.readbyqxmd.com/read/29344692/the-epidemiology-of-wrist-fractures-in-older-men-the-osteoporotic-fractures-in-men-mros-study
#7
N C Wright, E R Hooker, C M Nielson, K E Ensrud, S L Harrison, E S Orwoll, E Barrett-Connor
There is limited wrist fracture information on men. Our goal was to calculate frequency and identify risk factors for wrist fracture in the Osteoporotic Fractures in Men (MrOS) study. We confirmed that fracture history and certain medications are predictors, and identified novel predictors including markers of kidney function and physical performance. INTRODUCTION: To calculate the incidence of wrist fractures and their risk factors in older community-dwelling men from the US Osteoporotic Fractures in Men (MrOS) study...
January 17, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29344610/association-of-combined-patterns-of-tobacco-and-cannabis-use-in-adolescence-with-psychotic-experiences
#8
Hannah J Jones, Suzanne H Gage, Jon Heron, Matthew Hickman, Glyn Lewis, Marcus R Munafò, Stanley Zammit
Importance: There is concern about potentially causal effects of tobacco use on psychosis, but epidemiological studies have been less robust in attempts to minimize effects of confounding than studies of cannabis use have been. Objectives: To examine the association of patterns of cigarette and cannabis use with preceding and subsequent psychotic experiences, and to compare effects of confounding across these patterns. Design, Setting, and Participants: This cohort study used data from the Avon Longitudinal Study of Parents and Children, which initially consisted of 14 062 children...
January 17, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29344495/retinoblastoma-a-sixteen-year-review-of-the-presentation-treatment-and-outcome-from-a-tertiary-care-institute-in-northern-india
#9
Usha Singh, Deeksha Katoch, Savleen Kaur, Mangat Ram Dogra, Deepak Bansal, Rakesh Kapoor
Purpose: To study epidemiology, demographic profile, clinical characteristics, and outcome in pediatric patients with retinoblastoma. Methods: This was a retrospective review of retinoblastoma patients of a tertiary institute from January 1st 1998 to December 31st 2014. Results: The study included 467 patients (618 eyes) with a mean age of 34.7 ± 24.6 months (median = 30; 15 days to 144 months). Retinoblastoma was bilateral in 151 (32.3%) and there were 61...
December 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29344271/clinical-pathological-characteristics-and-prognostic-factors-for-papillary-thyroid-microcarcinoma-in-the-elderly
#10
Jing Tang, Hans B Liu, Lujiao Yu, Xin Meng, Sean X Leng, Haiyan Zhang
Background: The incidence of papillary thyroid microcarcinoma (PTMC) has increased dramatically over the past three decades worldwide. The annual rate of increase in the elderly (≥65) PTMC patients is 1.4 times higher than that in the adult (<65) PTMC patients. The aim of the present study is to identify the clinical-pathological characteristics and prognostic factors in the elderly PTMC patients. Methods: The source population is PTMC patients whose information is available in the Surveillance, Epidemiology and End Results (SEER) database (2004-2013)...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29344032/neck-circumference-percentiles-of-iranian-children-and-adolescents-the-weight-disorders-survey-of-caspian-iv-study
#11
Mostafa Hosseini, Mohammad Esmail Motlagh, Mahmoud Yousefifard, Mostafa Qorbani, Neamatollah Ataei, Hamid Asayesh, Mehdi Yaseri, Rasool Mohammadi, Masoud Baikpour, Arash Abbasi, Roya Kelishadi
Background: Neck circumference (NC), emerging as a key morphological index for pediatric obesity, is associated with obesity- and overweight-related detrimental conditions in children. In this study, we aimed to provide the age- and sex-specific percentile reference values for neck circumference of the Iranian children and adolescents. Methods: We used the data gathered through the weight disorders survey of CASPIAN IV study conducted in 2011 - 2012 in Iran, including a total of 21954 Iranian children and adolescents, composed of 10750 girls and 11204 boys, aged 7 - 18 years old...
October 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29343997/hospitalisation-in-patients-with-heart-failure-with-preserved-ejection-fraction
#12
REVIEW
Shane Nanayakkara, Hitesh C Patel, David M Kaye
Heart failure is highly prevalent with more than 50% of cases being patients with a preserved ejection fraction (HFPEF), a figure that is projected to increase due to the changing risk factor landscape, in particular the ageing population. Overall mortality is similar to patients with heart failure with reduced ejection fraction (HFREF), as are the rates of hospitalisation. Patients with HFPEF have more comorbid conditions with fewer therapeutic options available. In this review, we explore the epidemiology of hospitalisation of HFPEF, the impact of current treatment modalities, and the potential of future therapies...
2018: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/29343976/epidemiology-associated-burden-and-current-clinical-practice-for-the-diagnosis-and-management-of-alzheimer-s-disease-in-japan
#13
REVIEW
William Montgomery, Kaname Ueda, Margaret Jorgensen, Shari Stathis, Yuanyuan Cheng, Tomomi Nakamura
The burden of dementia in Japan is large and growing. With the world's fastest aging population, it is estimated that one in five elderly people will be living with dementia in Japan by 2025. The most common form of dementia is Alzheimer's disease (AD), accounting for around two-thirds of dementia cases. A systematic review was conducted to examine the epidemiology and associated burden of AD in Japan and to identify how AD is diagnosed and managed in Japan. English and Japanese language databases were searched for articles published between January 2000 and November 2015...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29343911/oncologic-outcomes-in-patients-with-nonurothelial-bladder-cancer
#14
Sanjay G Patel, Adam Benjamin Weiner, Kirk Keegan, Todd Morgan
Introduction: We aimed to evaluate the relative prognostic impact of the most common variant histologies on disease-specific survival (DSS) in patients undergoing radical cystectomy. Materials and Methods: The Surveillance, Epidemiology, and End Result database was used to identify patients who underwent radical cystectomy for bladder cancer from 1990 to 2007. Patients with urothelial cell carcinoma (UCC), squamous cell carcinoma (SCC), adenocarcinoma (AC), sarcoma, small cell carcinoma, signet ring carcinoma, and spindle cell carcinoma were included in the study...
January 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29343220/antimicrobial-resistance-of-neisseria-gonorrhoeae-in-germany-low-levels-of-cephalosporin-resistance-but-high-azithromycin-resistance
#15
Susanne Buder, Sandra Dudareva, Klaus Jansen, Anna Loenenbach, Sergejs Nikisins, Andrea Sailer, Eva Guhl, Peter K Kohl, Viviane Bremer
BACKGROUND: The widespread antimicrobial resistance of Neisseria gonorrhoeae is a serious problem for the treatment and control of gonorrhoea. Many of the previously effective therapeutic agents are no longer viable. Because N. gonorrhoeae infections are not reportable in Germany, only limited data on disease epidemiology and antimicrobial susceptibility patterns are available. The Gonococcal Resistance Network (GORENET) is a surveillance project to monitor trends in the antimicrobial susceptibility of N...
January 17, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29342999/-risk-factors-analysis-and-prognosis-of-renal-pelvis-dilatation-in-high-risk-infants-in-monocenter
#16
Q Fu, L R Fan, Y Shen, G J Zhou, H Z Yi, N Sun, J M Wang, L Q Jia, X M Wang, H Wang
Objective: To explore the prognosis and risk factors of pyelectasis in high-risk infants. Methods: This was a retrospective study. Totally 960 high-risk infants, who accepted type B ultrasonic examination for fetus at 28th week of gestation and for newborns in 48 hours after birth, were included in the study in departments of obstetrics and eonatology, Shunyi Maternal and Children's Hospital of Beijing Children's Hospital during May 2012 to April 2013. The degree of pyelectasis was classified using Grignon grade and the paients were followed up for 3 years...
January 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29342980/dietary-intake-of-flavonoids-and-ventilatory-function-in-european-adults-a-ga%C3%A2-len-study
#17
Vanessa Garcia-Larsen, Narjis Thawer, David Charles, Aedin Cassidy, Thibaut van Zele, Trine Thilsing, Matti Ahlström, Tari Haahtela, Thomas Keil, Paolo M Matricardi, Grzegorz Brożek, Marek L Kowalski, Joanna Makowska, Ewa Niżankowska-Mogilnicka, Barbara Rymarczyk, Carlos Loureiro, Ana Todo Bom, Claus Bachert, Bertil Forsberg, Christer Janson, Kjell Torén, James F Potts, Peter Gj Burney
BACKGROUND: Flavonoids exert anti-inflammatory properties and modulate oxidative stress in vitro, suggesting a protective effect on lung function, but epidemiological studies examining this association are scarce. METHODS: A stratified random sample was drawn from the GA²LEN screening survey, in which 55,000 adults aged 15 to 75 answered a questionnaire on respiratory symptoms. Post-bronchodilator spirometry was obtained from 2850 subjects. Forced vital capacity (FVC), the ratio between the forced exhaled volume in 1 second (FEV₁) and FVC (FEV₁/FVC), FVC below lower limit of normal (FVC < LLN), and FEV₁/FVC < LLN were calculated...
January 15, 2018: Nutrients
https://www.readbyqxmd.com/read/29342444/scarlet-fever-epidemic-in-china-caused-by-streptococcus-pyogenes-serotype-m12-epidemiologic-and-molecular-analysis
#18
Yuanhai You, Mark R Davies, Melinda Protani, Liam McIntyre, Mark J Walker, Jianzhong Zhang
From 2011, Hong Kong and mainland China have witnessed a sharp increase in reported cases, with subsequent reports of epidemic scarlet fever in North Asia and the United Kingdom. Here we examine epidemiological data and investigate the genomic context of the predominantly serotype M12 Streptococcus pyogenes scarlet fever isolates from mainland China. Incident case data was obtained from the Chinese Nationwide Notifiable Infectious Diseases Reporting Information System. The relative risk of scarlet fever in recent outbreak years 2011-2016 was calculated using the median age-standardised incidence rate, compared to years 2003-2010 prior this outbreak...
January 11, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29342279/incidence-and-predictors-of-post-transplant-lymphoproliferative-disease-after-kidney-transplantation-during-adulthood-and-childhood-a-registry-study
#19
Anna Francis, David W Johnson, Armando Teixeira-Pinto, Jonathan C Craig, Germaine Wong
Background: Differences in the epidemiology of post-transplant lymphoproliferative disease (PTLD) between adult and paediatric kidney transplant recipients remain unclear. Methods: Using the Australian and New Zealand Dialysis and Transplant Registry (1963-2015), the cumulative incidences of PTLD in children (age <20 years) and adults were calculated using a competing risk of death model and compared with age-matched population-based data using standardized incidence ratios (SIRs)...
January 12, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29342165/increased-colon-cancer-risk-after-severe-salmonella-infection
#20
Lapo Mughini-Gras, Michael Schaapveld, Jolanda Kramers, Sofie Mooij, E Andra Neefjes-Borst, Wilfrid van Pelt, Jacques Neefjes
BACKGROUND: Colon cancer constitutes one of the most frequent malignancies. Previous studies showed that Salmonella manipulates host cell signaling pathways and that Salmonella Typhimurium infection facilitates colon cancer development in genetically predisposed mice. This epidemiological study examined whether severe Salmonella infection, usually acquired from contaminated food, is associated with increased colon cancer risk in humans. METHODS AND FINDINGS: We performed a nationwide registry-based study to assess colon cancer risk after diagnosed Salmonella infection...
2018: PloS One
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