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Aging epidemiology

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https://www.readbyqxmd.com/read/28449361/systematic-review-with-meta-analysis-proximal-disease-extension-in-limited-ulcerative-colitis
#1
REVIEW
G Roda, N Narula, R Pinotti, A Skamnelos, K H Katsanos, R Ungaro, J Burisch, J Torres, J-F Colombel
BACKGROUND: Disease extent in ulcerative colitis is one of the major factors determining prognosis over the long-term. Disease extent is dynamic and a proportion of patients presenting with limited disease progress to more extensive forms of disease over time. AIM: To perform a systematic review and meta-analysis of epidemiological studies reporting on extension of ulcerative colitis to determine frequency of disease extension in patients with limited ulcerative colitis at diagnosis...
April 27, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28449278/seroepidemiology-and-molecular-characterization-of-hepatitis-e-virus-infection-in-swine-and-occupationally-exposed-workers-in-punjab-india
#2
M Bansal, S Kaur, D Deka, R Singh, J P S Gill
Hepatitis E virus (HEV) has two discrete epidemiological patterns: waterborne epidemics in developing countries only, caused by HEV genotype I, and sporadic zoonotic outbreaks in developing and developed countries caused by genotypes III and IV. This study was designed to investigate seroprevalence, molecular detection and the characterization of HEV by nested RT-PCR in swine as well as the occupational risk to exposed human population in Punjab state of north-western India. The occupational risk-exposed group comprised of swine farmers (organized - mixed feed feeders and unorganized - swill feeders), slaughterhouse workers, sewage workers and veterinary internes...
April 27, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28449214/a-rising-incidence-and-poorer-male-outcomes-characterise-early-onset-paediatric-inflammatory-bowel-disease
#3
A Coughlan, R Wylde, L Lafferty, S Quinn, A Broderick, B Bourke, S Hussey
BACKGROUND: The incidence of paediatric inflammatory bowel disease diagnosed before age 10 years is reportedly increasing, but national data are limited. AIM: To characterise the epidemiology, phenotype and clinical outcomes of children diagnosed with inflammatory bowel disease before age 10 years, and compare with data from children diagnosed aged 10-16 years. METHODS: A review of all Irish cases of early onset inflammatory bowel disease (diagnosis <10 years, EO-IBD) presenting between January 2000 and December 2014 was undertaken and compared to a cohort of later onset paediatric inflammatory bowel disease patients (diagnosis between 10 and 16 years, LO-IBD)...
April 27, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28448968/changing-epidemiological-patterns-in-traumatic-brain-injury-a-longitudinal-hospital-based-study-in-belgium
#4
Wouter Peeters, Marek Majdan, Alexandra Brazinova, Daan Nieboer, Andrew I R Maas
BACKGROUND: Various reports have suggested that epidemiological patterns of Traumatic Brain Injury (TBI) are changing in high-income countries, but the evidence to support this is often indirect and only a few longitudinal studies exist. We aimed to explore epidemiological patterns of TBI in Belgium over a 10-year period. METHODS: A retrospective analysis of Minimum Hospital Data provided by Statistics Belgium was performed for the period 2003-2012. ICD-9 classification was used to identify TBI and to differentiate subtypes...
April 28, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28448665/trends-in-the-incidence-prevalence-and-survival-outcomes-in-patients-with-neuroendocrine-tumors-in-the-united-states
#5
Arvind Dasari, Chan Shen, Daniel Halperin, Bo Zhao, Shouhao Zhou, Ying Xu, Tina Shih, James C Yao
Importance: The incidence and prevalence of neuroendocrine tumors (NETs) are thought to be rising, but updated epidemiologic data are lacking. Objective: To explore the evolving epidemiology and investigate the effect of therapeutic advances on survival of patients with NETs. Design, Setting, and Participants: A retrospective, population-based study using nationally representative data from the Surveillance, Epidemiology, and End Results (SEER) program was conducted to evaluate 64 971 patients with NETs from 1973 to 2012...
April 27, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28448192/epidemiology-of-newly-diagnosed-hypertensives-in-a-tertiary-care-hospital-in-a-developing-country
#6
Udaya Ralapanawa, Samath D Dharmaratne, KushaleePoornima Jayawickreme, Madhushanka Ekanayake
BACKGROUND: Cardiovascular diseases are the main cause of death in most countries and the past two decades have shown a global increase. Hypertension (HTN) was found to be the leading risk factor in 2010 as qualified by Disability Adjusted Life Years. Epidemiological studies in this regard in Sri Lanka are scarce. Thus, describing epidemiological patterns of HTN in the Sri Lankan population will help policy makers in planning preventive healthcare programs and aid in preparing strategies to cope with the increasing demand for healthcare facilities...
2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28448178/what-is-being-measured-a-comparison-of-two-depressive-symptom-severity-instruments-with-a-depression-diagnosis-in-low-income-high-risk-mothers
#7
Jenny Yang, Maria Martinez, Todd A Schwartz, Linda Beeber
BACKGROUND: Adequate assessment of depressive symptomatology is a necessary step toward decreasing income-related mental health treatment inequity. No studies have focused on comparing instruments used to detect depression in women from low-income backgrounds who are mothers of young children-a period of increased risk for depressive symptoms. METHODS: To address this gap, two commonly used instruments (Center for Epidemiologic Studies Depression Scale [CES-D] and Hamilton Rating Scale for Depression [Hamilton]) were compared with a depression diagnosis (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition [DSM-V]) in a sample (n = 251) of mothers from low-income backgrounds with children ranging from 1 to 54 months old...
April 27, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28447569/a-new-treatment-strategy-for-parkinson-s-disease-through-the-gut-brain-axis-the-glucagon-like-peptide-1-receptor-pathway
#8
Dong Seok Kim, Ho-Il Choi, Yun Wang, Yu Luo, Barry J Hoffer, Nigel H Greig
Molecular communications in the gut-brain axis, between the central nervous system and the gastrointestinal tract, arecritical for maintaining healthy brain function particularly in aging. Epidemiological analyses indicate type 2 diabetes mellitus (T2DM) is a risk factor for neurodegenerative disorders, including Alzheimer's disease (AD) and Parkinson's diseases (PD) for which aging shows a major correlative association. Common pathophysiological features exist between T2DM, AD and PD, including oxidative stress, inflammation, insulin resistance, abnormal protein processing and cognitive decline, and suggest that effective drugs for T2DM that positively impact the gut-brain axis could provide an effective treatment option for neurodegenerative diseases...
April 26, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28447347/abundance-of-the-benign-melanocytic-universe-dermoscopic-histopathological-correlation-in-nevi
#9
REVIEW
Nora Woltsche, Karin Schmid-Zalaudek, Teresa Deinlein, Katrin Rammel, Rainer Hofmann-Wellenhof, Iris Zalaudek
The broad universe of "melanocytic nevi" includes a variety of different subtypes, which can be classified either due to their morphology, epidemiology, genetic alterations or risk for developing melanoma. Regarding morphology, on the one hand macroscopic/clinical and on the other hand histopathological appearance were used to subdivide in the past, often resulting in confusion and poor interobserver agreement, while nowadays dermoscopy presents the clinician's precious bridge between naked-eye examination and histopathological diagnostics, allowing prediction of the lesions' histopathology, follow up and monitoring over time without need of excision...
May 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28447333/efficacy-and-tolerability-of-lithium-in-treating-acute-mania-in-youth-with-bipolar-disorder-protocol-for-a-systematic-review
#10
A Duffy, S Patten, S Goodday, A Weir, N Heffer, A Cipriani
BACKGROUND: Epidemiological, clinical, and high-risk studies have provided evidence that the peak period for onset of diagnosable episodes of mania and hypomania starts in mid-to-late adolescence. Moreover, clinically significant manic symptoms may occur even earlier, especially in children at familial risk. Lithium is the gold standard treatment for acute mania in adults, yet to our knowledge, there is no published systematic review assessing lithium treatment of mania in children or adolescents...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28447308/determinants-of-stage-at-diagnosis-of-breast-cancer-in-nigerian-women-sociodemographic-breast-cancer-awareness-health-care-access-and-clinical-factors
#11
Elima Jedy-Agba, Valerie McCormack, Oluwole Olaomi, Wunmi Badejo, Monday Yilkudi, Terna Yawe, Emmanuel Ezeome, Iliya Salu, Elijah Miner, Ikechukwu Anosike, Sally N Adebamowo, Benjamin Achusi, Isabel Dos-Santos-Silva, Clement Adebamowo
PURPOSE: Advanced stage at diagnosis is a common feature of breast cancer in Sub-Saharan Africa (SSA), contributing to poor survival rates. Understanding its determinants is key to preventing deaths from this cancer in SSA. METHODS: Within the Nigerian Integrative Epidemiology of Breast Cancer Study, a multicentred case-control study on breast cancer, we studied factors affecting stage at diagnosis of cases, i.e. women diagnosed with histologically confirmed invasive breast cancer between January 2014 and July 2016 at six secondary and tertiary hospitals in Nigeria...
April 26, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28447111/-diagnostics-and-treatment-of-osteoid-osteoma
#12
REVIEW
P Orth, D Kohn
BACKGROUND: Osteoid osteoma is the third most common benign bone tumor and typically induces pain that is worse at night. OBJECTIVE: To identify the epidemiological, pathogenetic, histological and radiological characteristics of osteoid osteoma and to present the broad variety of treatment options. MATERIAL AND METHODS: This review article summarizes relevant clinical studies and meta-analyses on this topic. RESULTS: Osteoid osteoma is characterized by a central nidus smaller than 1...
April 26, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28446570/prevalence-and-outcomes-of-achromobacter-species-infections-in-adults-with-cystic-fibrosis-a-north-american-cohort-study
#13
B D Edwards, J Greysson-Wong, R Somayaji, B Waddell, F J Whelan, D G Storey, H R Rabin, M G Surette, M D Parkins
Introduction:Achromobacter species are now increasingly recognized in CF, with unclear epidemiology and impact.Methods: We studied a cohort of patients attending a Canadian adult CF clinic who had positive sputum cultures for Achromobacter species from 1984-2013. Infection was categorized as transient or persistent (≥50% positive cultures in one year). Those with persistent infection were matched 2:1 with age, sex, and time-matched controls without history of Achromobacter infection and mixed effects models used to assess pulmonary exacerbation(PEx) frequency and lung function decline...
April 26, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28446454/epidemiology-of-injuries-in-judo-a-cross-sectional-survey-of-severe-injuries-based-on-time-loss-and-reduction-in-sporting-level
#14
Ralph Akoto, Christophe Lambert, Maurice Balke, Bertil Bouillon, Karl-Heinz Frosch, Jürgen Höher
BACKGROUND: Sport injury severity can be detected by duration of time loss and reduction of sporting performance. AIM: To detect injury type-specific time loss duration and sporting performance reduction in judo. METHODS: An online survey of active and former judo athletes was conducted (exclusion criterion: incomplete questionnaire). Only injuries causing more than 3 weeks' time loss were recorded. Athletes classified themselves into performance classes...
April 26, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28446261/epidemiological-characteristics-of-breakthrough-varicella-infection-during-varicella-outbreaks-in-shanghai-2008-2014
#15
Y F Zhu, Y F Li, Y DU, M Zeng
The outbreaks of varicella occurring in kindergartens and schools are increasingly notified in Shanghai despite the implementation of one-dose varicella vaccination. We analyzed surveillance data on the notified outbreaks of varicella in Minhang District of Shanghai during 2008-2014. A total of 13 511 varicella cases and 154 outbreaks involving 1558 (11·5%) cases were reported. Annual attack rates of outbreak-associated varicella in outbreak classes were 5·5%-12%. The mean age of the outbreak-associated cases was 8·6 ± 3·1 years...
April 27, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28446219/the-burden-epidemiology-costs-and-treatment-for-duchenne-muscular-dystrophy-an-evidence-review
#16
REVIEW
S Ryder, R M Leadley, N Armstrong, M Westwood, S de Kock, T Butt, M Jain, J Kleijnen
BACKGROUND: Duchenne Muscular Dystrophy (DMD) is a rapidly progressive, lethal neuromuscular disorder, present from birth, which occurs almost exclusively in males. We have reviewed contemporary evidence of burden, epidemiology, illness costs and treatment patterns of DMD. This systematic review adhered to published methods with information also sought from the web and contacting registries. Searches were carried out from 2005 to June 2015. The population of interest was individuals with clearly defined DMD or their carers...
April 26, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28446214/epidemiological-role-of-dogs-since-the-human-leishmaniosis-outbreak-in-madrid
#17
Guadalupe Miró, Aurora Müller, Ana Montoya, Rocía Checa, Valentina Marino, Eloy Marino, Fernando Fuster, Cristina Escacena, Miguel Angel Descalzo, Rosa Gálvez
BACKGROUND: Canine leishmaniosis (CanL) has been in the spotlight since the 2009 outbreak of human leishmaniosis in Madrid. In the framework of the Leishmaniosis Surveillance Programme set up in Madrid, this study examines Leishmania-specific seroprevalences in stray dogs for the outbreak area and rest of the Madrid region over the period spanning from the outbreak to the present (2009-2016). These data are of interest because stray dogs could be sentinels for disease surveillance in endemic areas...
April 26, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28446198/effect-of-anti-malarial-interventions-on-trends-of-malaria-cases-hospital-admissions-and-deaths-2005-2015-ghana
#18
Maru Aregawi, Keziah L Malm, Mohammed Wahjib, Osae Kofi, Naa-Korkor Allotey, Peprah Nana Yaw, Wilmot Abba-Baffoe, Sylvester Segbaya, Felicia Owusu-Antwi, Abderahmane T Kharchi, Ryan O Williams, Mark Saalfeld, Nibretie Workneh, Estifanos Biru Shargie, Abdisalan M Noor, Constance Bart-Plange
BACKGROUND: Since 2005, the Government of Ghana and its partners, in concerted efforts to control malaria, scaled up the use of artemisinin-based combination therapy (ACT) and insecticide-treated nets (ITNs). Beginning in 2011, a mass campaign of long-lasting insecticidal nets (LLINs) was implemented, targeting all the population. The impact of these interventions on malaria cases, admissions and deaths was assessed using data from district hospitals. METHODS: Records of malaria cases and deaths and availability of ACT in 88 hospitals, as well as at district level, ITN distribution, and indoor residual spraying were reviewed...
April 26, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28446117/prevalence-of-microcephaly-in-an-australian-population-based-birth-defects-register-1980-2015
#19
Michele Hansen, Paul K Armstrong, Carol Bower, Gareth S Baynam
OBJECTIVES: To describe the prevalence and characteristics of microcephaly in a geographically defined Australian population. DESIGN, SETTING AND PARTICIPANTS: Descriptive epidemiological study of microcephaly cases ascertained by the Western Australian Register of Developmental Anomalies, 1980-2015, defining microcephaly as an occipito-frontal head circumference below the third percentile or more than two standard deviations below the mean sex- and age-appropriate distribution curve...
May 1, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28446068/multiplex-pcr-detection-of-cryptosporidium-sp-giardia-lamblia-and-entamoeba-histolytica-directly-from-dried-stool-samples-from-guinea-bissauan-children-with-diarrhoea
#20
Sointu Mero, Juha Kirveskari, Jenni Antikainen, Johan Ursing, Lars Rombo, Poul-Erik Kofoed, Anu Kantele
BACKGROUND: In developing countries, diarrhoea is the most common cause of death for children under five years of age, with Giardia lamblia, Cryptosporidium and Entamoeba histolytica as the most frequent pathogenic parasites. Traditional microscopy for stool parasites has poor sensitivity and specificity, while new molecular methods may provide more accurate diagnostics. In poor regions with sample storage hampered by uncertain electricity supply, research would benefit from a method capable of analysing dried stools...
April 27, 2017: Infectious Diseases
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