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https://www.readbyqxmd.com/read/29333595/implanted-closed-loop-gastric-electrical-stimulation-clges-system-with-sensor-based-feedback-safely-limits-weight-regain-at-24%C3%A2-months
#1
S Morales-Conde, I Alarcón Del Agua, L Busetto, F Favretti, M Anselmino, G M Rovera, M Socas-Macias, A Barranco-Moreno, R Province-Azalde, A J Torres
BACKGROUND: Weight regain following bariatric surgery is not uncommon. Safe, effective weight loss treatment up to 1 year has been reported with the closed-loop gastric electrical stimulation (CLGES) system. Continuous recording of eating and activity behavior by onboard sensors is one of the novel features of this closed-loop electrical stimulation therapy, and may provide improved long-term weight maintenance by enhancing aftercare. METHODS: Four centers participating in a 12-month prospective multicenter randomized study monitored all implanted participants (n = 47) up to 24 months after laparoscopic implantation of a CLGES system...
January 15, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29332739/multifidus-muscle-size-in-adolescents-with-and-without-back-pain-using-ultrasonography
#2
Nahid Rahmani, Ali Kiani, Mohammad Ali Mohseni-Bandpei, Iraj Abdollahi
OBJECTIVE: The purposes of this study were; a) to compare multifidus muscle cross sectional area (CSA) in male adolescents suffering from low back pain (LBP) with healthy male adolescents using ultrasonography (US), and b) to assess the correlation between multifidus muscle size and demographic variables. METHODS: A random sample of 40 healthy boys (as a control group) and 40 boys with LBP (as an experimental group) at the age range of 15-18 years was recruited in the present cohort study...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332061/design-and-implementation-of-an-advanced-telemedicine-model-for-the-rural-people-of-bangladesh
#3
Uzzal Kumar Prodhan, Mohammad Zahidur Rahman, Israt Jahan
OBJECTIVES: Telemedicine based healthcare service faces different difficulties especially in the remote people of Bangladesh. The objective of this study was to implement an advanced telemedicine model in order to provide the healthcare services for the rural people of Bangladesh. METHODS: We developed the telemedicine model using an ardunio based low cost portable telemedicine tool kit by interfacing android application. Then we collected ECG, blood pressure, temperature, concentration of glucose in blood, SPO2, body position, airflow, height and weight through our developed model...
January 5, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29331653/gallic-acid-attenuates-type-i-diabetic-nephropathy-in-rats
#4
Mayuresh Sudamrao Garud, Yogesh Anant Kulkarni
Literatures suggest that TGF-β1 have a central role in the progression of diabetic nephropathy and its down regulation can improve the disease condition. Oxidative stress, generation of advanced glycation end products and activation of renin angiotensin system are the connecting links between hyperglycemia and TGF-β1 over expression. Gallic acid is a phytochemical having wide range of biological activities. Gallic acid is reported to have antioxidant and advanced glycation inhibitory activity. It has also shown inhibitory effects on angiotensin converting enzyme...
January 10, 2018: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29330101/telephone-based-weight-loss-support-for-patients-with-knee-osteoarthritis-a-pragmatic-randomized-controlled-trial
#5
Kate M O'Brien, John Wiggers, Amanda Williams, Elizabeth Campbell, Rebecca K Hodder, Luke Wolfenden, Sze Lin Yoong, Emma K Robson, Robin Haskins, Steven J Kamper, Chris Rissel, Christopher M Williams
OBJECTIVE: To determine the effectiveness of telephone-based weight loss support in reducing the intensity of knee pain in patients with knee osteoarthritis, who are overweight or obese, compared to usual care. DESIGN: We conducted a parallel randomized controlled trial (RCT), embedded within a cohort multiple RCT of patients on a waiting list for outpatient orthopaedic consultation at a tertiary referral hospital in NSW, Australia. Patients with knee osteoarthritis, classified as overweight or obese (body mass index between ≥27kg/m2 and <40kg/m2) were randomly allocated to receive referral to an existing non-disease specific government funded 6-month telephone-based weight management and healthy lifestyle service or usual care...
January 9, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29329954/comparative-myology-of-the-ankle-of-leopardus-wiedii-and-l-geoffroyi-carnivora-felidae-functional-consistency-with-osteology-locomotor-habits-and-hunting-in-captivity
#6
Miriam M Morales, S Rocío Moyano, Agustina M Ortiz, Marcos D Ercoli, Luis I Aguado, Sergio A Cardozo, Norberto P Giannini
Leopardus wiedii (margay) is the only arboreal Neotropical felid able to climb head-first down trees, due to its ability to rotate its tarsal joint 180°. A closely related, similar-sized species, L. geoffroyi (Geoffroy's cat) exhibits more typical terrestrial habits and lacks the arboreal capabilities of L. wiedii. There is osteological evidence that supports a mechanical specialization of L. wiedii's tarsal joint for inversion, but there have been no studies on the myology of this specialization. Based on comparative gross-anatomy dissections of zeugo- and autopodial muscles related to the ankle joint of one margay specimen and two Geoffroýs cats, we identified myological specializations of L...
December 26, 2017: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/29329796/the-evolving-face-of-myocardial-reperfusion-in-acute-coronary-syndromes-a-primer-for-the-internist
#7
REVIEW
R Jay Widmer, Peter M Pollak, Malcolm R Bell, Bernard J Gersh, Nandan S Anavekar
Acute coronary syndromes (ACSs) account for a large proportion of disease burden in the United States and worldwide, and our understanding of ACS management continues to evolve. In this review we take a practical approach to evaluating and treating a patient with ACS, focusing on the optimal timing and methods of coronary reperfusion. Beginning with initial assessment and risk stratification, a provider managing the patient with ACS must be able to expeditiously decide on and implement the correct guideline-directed pathway to optimize outcomes...
January 9, 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29329773/total-energy-expenditure-and-body-composition-of-children-with-developmental-disabilities
#8
Michele Polfuss, Kathleen J Sawin, Paula E Papanek, Linda Bandini, Bethany Forseth, Andrea Moosreiner, Kimberley Zvara, Dale A Schoeller
BACKGROUND: Obesity prevalence is increased in children with developmental disabilities, specifically in children with spina bifida and Down syndrome. Energy expenditure, a critical aspect of weight management, has been extensively studied in the typically developing population, but not adequately studied in children with developmental disabilities. OBJECTIVE: Determine energy expenditure, fat-free mass and body fat percentile and the impact of these findings on recommended caloric intake in children with spina bifida and Down syndrome...
December 28, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/29329261/sitting-posture-monitoring-system-based-on-a-low-cost-load-cell-using-machine-learning
#9
Jongryun Roh, Hyeong-Jun Park, Kwang Jin Lee, Joonho Hyeong, Sayup Kim, Boreom Lee
Sitting posture monitoring systems (SPMSs) help assess the posture of a seated person in real-time and improve sitting posture. To date, SPMS studies reported have required many sensors mounted on the backrest plate and seat plate of a chair. The present study, therefore, developed a system that measures a total of six sitting postures including the posture that applied a load to the backrest plate, with four load cells mounted only on the seat plate. Various machine learning algorithms were applied to the body weight ratio measured by the developed SPMS to identify the method that most accurately classified the actual sitting posture of the seated person...
January 12, 2018: Sensors
https://www.readbyqxmd.com/read/29329084/sources-of-polychlorinated-dibenzo-p-dioxins-and-dibenzofurans-and-biphenyls-in-chinese-mitten-crabs
#10
Ying Han, Wenbin Liu, Wen Zhu, Kaifeng Rao, Ke Xiao, Lirong Gao, Guijin Su, Guorui Liu
Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) in Chinese mitten crabs from several areas were determined. The toxic equivalents (TEQs) for the mean PCDD/F and total PCDD/F and dioxin-like PCBs were 2.9 ± 2.7 and 5.7 ± 4.0 pg TEQ g-1, respectively. The mean concentrations of PCBs and dl-PCBs were 282 and 59 times the concentrations of PCDD/Fs, respectively. PCDD/F and PCB sources in the crab food web were assessed. The total TEQ of PCDD/F and PCB supplied by crab compound feed was 2...
January 6, 2018: Chemosphere
https://www.readbyqxmd.com/read/29327400/a-vitamin-b12-conjugate-of-exendin-4-improves-glucose-tolerance-without-associated-nausea-or-hypophagia-in-rodents
#11
Elizabeth G Mietlicki-Baase, Claudia G Liberini, Jayme L Workinger, Ron L Bonaccorso, Tito Borner, David J Reiner, Kieran Koch-Laskowski, Lauren E McGrath, Rinzin Lhamo, Lauren M Stein, Bart C De Jonghe, George G Holz, Christian L Roth, Robert P Doyle, Matthew R Hayes
AIMS: While pharmacological glucagon-like peptide-1 receptor (GLP-1R) agonists are FDA-approved for treating type 2 diabetes mellitus (T2DM) and obesity, a major side effect is nausea/malaise. We recently developed a conjugate of vitamin B12 bound to the GLP-1R agonist exendin-4 (Ex4), which displays enhanced proteolytic stability and retention of GLP-1R agonism. Here, we evaluate whether the conjugate (B12-Ex4) can improve glucose tolerance without producing anorexia and malaise. MATERIALS AND METHODS: We evaluated the effects of systemic B12-Ex4 and unconjugated Ex4 on food intake and body weight change, oral glucose tolerance, and nausea/malaise in male rats, and on intraperitoneal glucose tolerance in mice...
January 12, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29327380/effects-of-deficiency-and-surplus-dietary-threonine-on-reproductive-performance-of-primiparous-pregnant-gilts
#12
M Shi, T Liu, T Li, H Wang, T Yuan, D Li, J Wang
Dietary threonine imbalance is known to impair reproductive performances of gestating sows, but the underlying mechanisms are largely unknown. In this study, effects of deficiency and surplus dietary threonine during gestation on reproductive performance, serum metabolites and hormones concentration, and colostral nutrient and immunoglobulin contents of primiparous sows were investigated. Ninety primiparous pregnant gilts were assigned to one of the three dietary treatments with different standardized ileal digestible threonine/lysine ratios at 0...
January 11, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29326826/collision-tumor-consisting-of-a-colorectal-adenocarcinoma-and-dissemination-of-a-gastric-adenocarcinoma
#13
Ryoichi Miyamoto, Kazunori Kikuchi, Atsushi Uchida, Masayoshi Ozawa, Akira Kemmochi, Naoki Sano, Sosuke Tadano, Satoshi Inagawa, Shinya Adachi, Masayoshi Yamamoto
Background: Collision tumors, composed of histologically distinct tumor types, are rare entities, especially in the colorectum, and corresponding evidence-based clinical management or treatment strategies are poorly defined. This is the first report of a collision tumor composed of two histologically distinct adenocarcinomas. Case presentation: A 78-year-old male showed severe anemia and a 10% body weight loss over 1 month. Preoperative examination revealed T3N1M0 stage IIIA gastric cancer and T3N0M0 stage IIA rectal cancer...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29325839/the-effect-of-low-load-exercise-on-joint-pain-function-and-activities-of-daily-living-in-patients-with-knee-osteoarthritis
#14
Jason Peeler, Jacquie Ripat
BACKGROUND: Knee osteoarthritis has a lifetime risk of nearly one in two, with obese individuals being most susceptible. While exercise is universally recognized as a critical component for management, unsafe or ineffective exercise frequently leads to exacerbation of joint symptoms. AIM: Evaluate the effect of a 12week lower body positive pressure (LBPP) supported low-load treadmill walking program on knee pain, joint function, and performance of daily activities in patients with knee osteoarthritis (OA)...
January 8, 2018: Knee
https://www.readbyqxmd.com/read/29325665/feasibility-and-acceptability-of-delivering-a-postpartum-weight-loss-intervention-via-facebook-a-pilot-study
#15
Molly E Waring, Tiffany A Moore Simas, Jessica Oleski, Rui S Xiao, Julie A Mulcahy, Christine N May, Sherry L Pagoto
OBJECTIVE: To evaluate the feasibility and acceptability of a Facebook-delivered postpartum weight loss intervention. METHODS: Overweight and obese postpartum women received a 12-week weight loss intervention via Facebook. Feasibility outcomes were recruitment, retention, engagement, and acceptability. Weight loss was an exploratory outcome. RESULTS: Participants (n = 19) were 3.5 (SD 2.2) months postpartum with a baseline body mass index of 30...
January 2018: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/29325657/my-quest-an-intervention-using-text-messaging-to-improve-dietary-and-physical-activity-behaviors-and-promote-weight-loss-in-low-income-women
#16
Jamie B Griffin, Barb Struempler, Katie Funderburk, Sondra M Parmer, Cecilia Tran, Danielle D Wadsworth
OBJECTIVE: To evaluate changes in dietary and physical activity behaviors and weight after implementation of a 12-week text messaging initiative (My Quest). DESIGN: The researchers conducted a 1-group, pre- to posttest study design to determine changes after implementation of a text messaging initiative developed using the tenets of the Social Cognitive Theory. SETTING: A total of 55 Alabama counties (84% rural) with high rates of poverty, overweight/obesity, and chronic diseases...
January 2018: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/29323932/the-effects-of-breath-alcohol-concentration-on-postural-control
#17
Dary D Fiorentino
STRUCTURED ABSTRACT Background: Two of the three standardized field sobriety tests that US law enforcement uses at roadside checks have a postural equilibrium component to them. Those tests have been validated to detect impairment caused by blood alcohol concentrations (BACs) of .08 g/dL or above. Many medical and traffic safety associations support a lower limit, and one state, Utah, has passed a law to lower the limit to .05 g/dL. Many studies have examined the effects of alcohol on postural control (of which postural equilibrium is a component), with a consensus emerging that impairment is usually found at BACs greater than ...
January 11, 2018: Traffic Injury Prevention
https://www.readbyqxmd.com/read/29322010/beneficiary-effect-of-commiphora-mukul-ethanolic-extract-against-high-fructose-diet-induced-abnormalities-in-carbohydrate-and-lipid-metabolism-in-wistar-rats
#18
Ramesh Bellamkonda, Rasineni Karuna, Bongu Sasi Bhusana Rao, Ketham Haritha, Bengeppagari Manjunatha, Somavarapu Silpa, Desireddy Saralakumari
The present study was proposed to elucidate the effect of Commiphora mukul gum resin elthanolic extract treatment on alterations in carbohydrate and lipid metabolisms in rats fed with high-fructose diet. Male Wistar rats were divided into four groups: two of these groups (group C and C+CM) were fed with standard pellet diet and the other two groups (group F and F+CM) were fed with high fructose (66 %) diet. C. mukul suspension in 5% Tween-80 in distilled water (200 mg/kg body weight/day) was administered orally to group C+CM and group F+CM...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29320996/healthy-apple-program-to-support-child-care-centers-to-alter-nutrition-and-physical-activity-practices-and-improve-child-weight-a-cluster-randomized-trial
#19
Jodi D Stookey, Jane Evans, Curtis Chan, Lisa Tao-Lew, Tito Arana, Susan Arthur
BACKGROUND: North Carolina Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) resources improve child body mass index (BMI) when the resources are introduced by nurses to child care providers, and offered with workshops and incentives. In San Francisco, public health and child care agencies partnered to adapt NAP SACC resources into an annual "Healthy Apple" quality improvement program (HAP). METHODS: This cluster randomized controlled trial pilot-tested integration of the HAP with bi-annual public health screenings by nurses...
December 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29320575/azp-531-an-unacylated-ghrelin-analog-improves-food-related-behavior-in-patients-with-prader-willi-syndrome-a-randomized-placebo-controlled-trial
#20
Soraya Allas, Assumpta Caixàs, Christine Poitou, Muriel Coupaye, Denise Thuilleaux, Françoise Lorenzini, Gwenaëlle Diene, Antonino Crinò, Frédéric Illouz, Graziano Grugni, Diane Potvin, Sarah Bocchini, Thomas Delale, Thierry Abribat, Maithé Tauber
CONTEXT AND OBJECTIVE: Prader-Willi syndrome (PWS) is characterized by early-onset hyperphagia and increased circulating levels of the orexigenic Acylated Ghrelin (AG) hormone with a relative deficit of Unacylated Ghrelin (UAG). AZP-531, a first-in-class UAG analog, was shown to inhibit the orexigenic effect of AG in animals, to improve glycemic control and decrease body weight in humans. We aimed to investigate the safety and efficacy of AZP-531 in patients with PWS for whom no approved treatment for hyperphagia is currently available...
2018: PloS One
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