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https://www.readbyqxmd.com/read/29456832/interleukin-25-and-eosinophils-progenitor-cell-mobilization-in-allergic-asthma
#1
Wei Tang, Steven G Smith, Wei Du, Akash Gugilla, Juan Du, John Paul Oliveria, Karen Howie, Brittany M Salter, Gail M Gauvreau, Paul M O'Byrne, Roma Sehmi
Background: Eosinophil-lineage committed progenitor cells (EoP) migrate from the bone marrow and differentiate locally to provide an ongoing source of mature eosinophils in asthmatic inflammatory responses in the airways. Sputum levels of EoP are increased in asthmatics compared to normal controls suggesting an exaggerated eosinophilopoietic environment in the airways. Understanding what factors promote EoP traffic to the airways is important to understand the diathesis of asthma pathology...
2018: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29454563/radiological-and-clinical-outcomes-of-medial-approach-open-reduction-by-using-two-intervals-in-developmental-dysplasia-of-the-hip
#2
Afsar T Ozkut, Yusuf Iyetin, Omer K Unal, M Salih Soylemez, Esat Uygur, Irfan Esenkaya
OBJECTIVE: To evaluate the midterm clinical and radiological outcomes of the medial approach using two intervals for developmental hip dysplasia (DDH). METHODS: The study involved 62 hips of 47 patients (41 girls, 6 boys) treated with medial approach for DDH from 1999 to 2010. The age of the patients at surgery was 18.7 ± 2.25 months. Follow up of the patients was 11.3 ± 3.07 years. The age of the patients at the last follow up was 12.6 ± 1.74 years. According to the Tönnis classification, 13 hips were grade II, 27 hips were grade III and 22 hips were grade IV...
February 14, 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29454139/implantation-of-the-subcutaneous-implantable-cardioverter-defibrillator-with-truncal-plane-blocks
#3
Marc A Miller, Himani V Bhatt, Menachem Weiner, Tom F Brouwer, Alexander J Mittnacht, Ali Shariat, Christina Jeng, Caroline Eden, Hung-Mo Lin, Benjamin Salter, Srinivas R Dukkipati, Vivek Y Reddy
No abstract text is available yet for this article.
February 14, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29448398/editorial-a-tale-of-two-anniversaries-125-years-of-the-physical-review-and-25-years-of-physical-review-e
#4
Matthew Salter, Michael Thoennessen
No abstract text is available yet for this article.
January 2018: Physical Review. E
https://www.readbyqxmd.com/read/29433409/endovascular-management-of-svc-syndrome-due-to-fibrosing-mediastinitis-a-feasibility-and-safety-analysis
#5
Shamaita Majumdar, Ramy Shoela, David J Kim, Raja Ramaswamy, Naganathan Mani, Amber Salter, Olaguoke Akinwande
PURPOSE: To assess the outcomes of endovascular management for superior vena cava (SVC) syndrome secondary to fibrosing mediastinitis (FM). METHODS: Between January 2004 and December 2016, 10 consecutive patients with endovascularly managed SVC syndrome secondary to FM were identified in an institutional database. Venograms were performed to assess the severity and location of the lesion and allow measurement for stent selection. Standard stenting and angioplasty techniques were utilized to establish luminal patency...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29411625/mortality-among-people-living-with-hiv-aids-with-non-small-cell-lung-cancer-in-the-modern-haart-era
#6
Danielle M Smith, Kate A Salters, Oghenowede Eyawo, Conrado Franco-Villalobos, Shahab Jabbari, Sam M Wiseman, Natasha Press, Julio S G Montaner, S F Paul Man, Mark Hull, Robert S Hogg
People living with HIV (PLWHA) with adequate access to modern combination antiretroviral therapy (cART) are living longer and experiencing reduced AIDS-related morbidity and mortality. However, increases in non-AIDS related conditions, such as certain cancers, have accompanied these therapeutic advances over time. As such, our study objective was to determine the impact of HIV on all-cause and lung cancer-specific mortality amongst PLWHA with diagnoses of non-small-cell lung cancer (NSCLC) and HIV-negative individuals with NSCLC...
February 7, 2018: AIDS Care
https://www.readbyqxmd.com/read/29410539/risk-factors-and-prognostic-significance-of-altered-left-ventricular-geometry-in-preterm-infants
#7
Swati Choudhry, Amber Salter, Tyler W Cunningham, Philip T Levy, Brian P Hackett, Gautam K Singh, Mark C Johnson
OBJECTIVE: Left ventricular (LV) hypertrophy (LVH) predicts adverse cardiac events in adults. We sought to determine the risk factors and prognostic significance of altered LV geometry in preterm infants. STUDY DESIGN: In an echocardiographic, single-center, retrospective case-control study we investigated the risk factors and outcomes in patients with altered LV geometry (either increased left ventricular mass index (LVMI) or increased relative wall thickness (RWT)) from a cohort of 503 preterm infants ≤2 kg...
February 6, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29409423/isolated-salter-harris-type-iii-physeal-fracture-of-the-distal-ulna
#8
Kiminori Yukata, Sho Nakai, Masaki Ikeda, Jun-Ichi Hamawaki
We describe a case of isolated physeal fracture of ulna distal end in a 13-year-old boy. This fracture type is uncommon, especially Salter-Harris type III of this injury has not been reported. Plain radiographs showed a small vertical fracture line at the ulnar distal end and an enlargement of epiphyseal plate at the base of ulnar styloid process. The present case was successfully managed with conservative treatment because of its minimal displacement.
March 2018: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29409076/the-primary-physis
#9
James M Brian, David H Choi, Michael M Moore
The primary physis is responsible for long bone growth in children and adolescents. Injury and physiologic or metabolic stress to the primary physis present unique radiologic findings that are important for radiologists to recognize and diagnose. Appreciation of the anatomy and histology of the primary physis forms the basis for understanding the imaging findings associated with pathologic conditions affecting the primary physis. Salter-Harris injuries, physeal bars, growth arrest lines, rickets, and focal periphyseal edema zones are common conditions with recognizable radiologic presentations...
February 2018: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/29398369/transient-relative-age-effects-across-annual-age-groups-in-national-level-australian-swimming
#10
Stephen Cobley, Shaun Abbott, Sera Dogramaci, Adam Kable, James Salter, Mirjam Hintermann, Michael Romann
OBJECTIVES: To determine the prevalence, magnitude and transient patterning of Relative Age Effects (RAEs) according to sex and stroke event across all age-groups at the Australian National age swimming Championships. DESIGN: Repeated years of cross-sectional participation data were examined. METHODS: Participants were 6014 unique male (3185) and female (2829) swimmers (aged 12-18 years) who participated in Freestyle (50, 400m) and/or Breaststroke (100, 200m) at the National age swimming Championships between 2000-2014 (inclusive)...
December 29, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29375889/national-estimates-of-self-reported-sitting-time-in-adults-with-multiple-sclerosis
#11
J E Sasaki, R W Motl, G Cutter, R A Marrie, T Tyry, A Salter
Background: Limited data exist on the prevalence and distribution of sedentary behavior (SB) in multiple sclerosis (MS). Objective: The objective of this paper is to describe sitting time as a metric of SB in a large national sample of people with MS. Methods: A total of 8004 individuals from the North American Research Committee on MS (NARCOMS) Registry completed the sitting time question from the International Physical Activity Questionnaire in spring 2015...
January 2018: Multiple Sclerosis Journal—Experimental, Translational and Clinical
https://www.readbyqxmd.com/read/29350944/editorial-a-tale-of-two-anniversaries-125%C3%A2-years-of-the-physical-review-and-25%C3%A2-years-of-physical-review-e
#12
Matthew Salter, Michael Thoennessen
No abstract text is available yet for this article.
January 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29331972/cohort-profile-the-comparative-outcomes-and-service-utilization-trends-coast-study-among-people-living-with-and-without-hiv-in-british-columbia-canada
#13
Oghenowede Eyawo, Mark W Hull, Kate Salters, Hasina Samji, Angela Cescon, Paul Sereda, Viviane D Lima, Bohdan Nosyk, David G T Whitehurst, Scott A Lear, Julio S G Montaner, Robert S Hogg
PURPOSE: The Comparative Outcomes And Service Utilization Trends (COAST) Study in British Columbia (BC), Canada, was designed to evaluate the determinants of health outcomes and health care services use among people living with HIV (PLHIV) as they age in the period following the introduction of combination antiretroviral therapy (cART). The study also assesses how age-associated comorbidities and health care use among PLHIV may differ from those observed in the general population. PARTICIPANTS: COAST was established through a data linkage between two provincial data sources: The BC Centre for Excellence in HIV/AIDS Drug Treatment Program, which centrally manages cART dispensation across BC and contains prospectively collected data on demographic, immunological, virological, cART use and other clinical information for all known PLHIV in BC; and Population Data BC, a provincial data repository that holds individual event-level, longitudinal data for all 4...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29330144/kindlin-1-promotes-pulmonary-breast-cancer-metastasis
#14
Sana Sarvi, Hitesh Patel, Jun Li, Georgia L Dodd, Helen Creedon, Morwenna Muir, Jocelyn Ward, John C Dawson, Martin Lee, Jayne Culley, Donald M Salter, Andrew H Sims, Adam Byron, Valerie G Brunton
In breast cancer, increased expression of the cytoskeletal adaptor protein Kindlin-1 has been linked to increased risks of lung metastasis, but the functional basis is unknown. Here we show that in a mouse model of polyomavirus middle T antigen-induced mammary tumorigenesis, loss of Kindlin-1 reduced early pulmonary arrest and later development of lung metastasis. This phenotype relied on the ability of Kindlin-1 to bind and activate β integrin heterodimers. Kindlin-1 loss reduced α4 integrin-mediated adhesion of mammary tumor cells to the adhesion molecule VCAM-1 on endothelial cells...
January 12, 2018: Cancer Research
https://www.readbyqxmd.com/read/29324529/inappropriately-timed-pediatric-orthopaedic-referrals-from-the-emergency-department-result-in-unnecessary-appointments-and-financial-burden-for-patients
#15
Taylor J Jackson, Todd J Blumberg, Apurva S Shah, Wudbhav N Sankar
BACKGROUND: Musculoskeletal injuries are among the most common reasons for emergency department (ED) visits in the pediatric population. Many such injuries can be managed with a single follow-up outpatient visit. However, untimely (ie, premature) referrals by emergency physicians to orthopaedic surgeons are common and may inadvertently create need for a second visit, generating unnecessary expenditures. We sought to elucidate the cost of premature musculoskeletal follow-up visits to the patients, families, and the health care system...
January 10, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29315083/capture-consistently-acquired-projections-for-tuned-and-robust-estimation-a-self-navigated-respiratory-motion-correction-approach
#16
Cihat Eldeniz, Tyler Fraum, Amber Salter, Yasheng Chen, H Michael Gach, Parag J Parikh, Kathryn J Fowler, Hongyu An
OBJECTIVES: In this study, we present a fully automated and robust self-navigated approach to obtain 4-dimensional (4-D) motion-resolved images during free breathing. MATERIALS AND METHODS: The proposed method, Consistently Acquired Projections for Tuned and Robust Estimation (CAPTURE), is a variant of the stack-of-stars gradient-echo sequence. A 1-D navigator was consistently acquired at a fixed azimuthal angle for all stacks of spokes to reduce nonphysiological signal contamination due to system imperfections...
January 8, 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29276627/patient-and-public-involvement-in-health-literacy-interventions-a-mapping-review
#17
Stephanie Howard Wilsher, Julii Brainard, Yoon Loke, Charlotte Salter
Plain English summary: If people can read, understand and act on health information to better their health and reduce illness, they are thought to have "adequate" health literacy. Poor health literacy can mean people are less able to access health care and manage their health. Health literacy tends to worsen as adults get older, and is especially poor in adults age 65 and over. Ideally, health literacy interventions target people before age 65, to establish good skills and habits before people have many health problems associated with ageing...
2017: Research Involvement and Engagement
https://www.readbyqxmd.com/read/29275057/treatment-satisfaction-and-bothersome-bladder-bowel-sexual-symptoms-in-multiple-sclerosis
#18
Guoqiao Wang, Ruth Ann Marrie, Robert J Fox, Tuula Tyry, Stacey S Cofield, Gary R Cutter, Amber Salter
BACKGROUND: Bladder, bowel, and sexual symptoms are common among persons with multiple sclerosis (MS). We aimed to investigate the frequency and severity of bladder, bowel, and sexual symptoms, the relationships between these symptoms, satisfaction with treatment of these symptoms, and factors associated with symptom severity and treatment satisfaction. METHODS: In the fall 2010, we surveyed participants in the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry regarding the severity of being bothered by bladder, bowel, and sexual symptoms, their satisfaction of health providers' inquiry and treatment with these symptoms, and whether their quality of life (QOL) had changed with the treatment...
December 14, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29260304/denali-tulip-and-option-inferior-vena-cava-filter-retrieval-a-single-center-experience
#19
Raja S Ramaswamy, Emily Jun, Darren van Beek, Naganathan Mani, Amber Salter, Seung K Kim, Olaguoke Akinwande
PURPOSE: To compare the technical success of filter retrieval in Denali, Tulip, and Option inferior vena cava filters. MATERIALS AND METHODS: A retrospective analysis of Denali, Gunther Tulip, and Option IVC filters was conducted. Retrieval failure rates, fluoroscopy time, sedation time, use of advanced retrieval techniques, and filter-related complications that led to retrieval failure were recorded. RESULTS: There were 107 Denali, 43 Option, and 39 Tulip filters deployed and removed with average dwell times of 93...
December 19, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29246219/cellular-pharmacodynamic-effects-of-pycnogenol%C3%A2-in-patients-with-severe-osteoarthritis-a-randomized-controlled-pilot-study
#20
RANDOMIZED CONTROLLED TRIAL
Steffen Jessberger, Petra Högger, Franca Genest, Donald M Salter, Lothar Seefried
BACKGROUND: The standardized maritime pine bark extract (Pycnogenol®) has previously shown symptom alleviating effects in patients suffering from moderate forms of knee osteoarthritis (OA). The cellular mechanisms for this positive impact are so far unknown. The purpose of the present randomized pilot controlled study was to span the knowledge gap between the reported clinical effects of Pycnogenol® and its in vivo mechanism of action in OA patients. METHODS: Thirty three patients with severe OA scheduled for a knee arthroplasty either received 100 mg of Pycnogenol® twice daily or no treatment (control group) three weeks before surgery...
December 16, 2017: BMC Complementary and Alternative Medicine
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