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Mri and prostate biopsy

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https://www.readbyqxmd.com/read/28635568/additional-value-of-magnetic-resonance-targeted-biopsies-to-standard-transrectal-ultrasound-guided-biopsies-for-detection-of-clinically-significant-prostate-cancer
#1
Catrin von Below, Cecilia Wassberg, Mona Norberg, Anna Tolf, Joel Kullberg, Sam Ladjevardi, Michael Häggman, Anna Bill Axelson, Håkan Ahlström
OBJECTIVE: The aim of this study was to evaluate the additional value of magnetic resonance imaging-targeted biopsy (MRI-TB) to standard transrectal ultrasound-guided biopsy (SB) for detection of clinically significant prostate cancer (PCa). An additional aim was to compare the biopsy results to MRI evaluation using a Likert scale. MATERIALS AND METHODS: Patients with newly diagnosed localized PCa (n = 53) by clinical routine SB were prospectively included. The majority of the patients were scheduled for curative therapy before enrollment...
February 24, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28632688/high-quality-3-dimensional-1h-magnetic-resonance-spectroscopic-imaging-of-the-prostate-without-endorectal-receive-coil-using-a-semi-laser-sequence
#2
Nassim Tayari, Isabell K Steinseifer, Kirsten M Selnæs, Tone F Bathen, Marnix C Maas, Arend Heerschap
OBJECTIVES: Inclusion of 3-dimensional H magnetic resonance spectroscopic imaging (3D-H-MRSI) in routine multiparametric MRI of the prostate requires good quality spectra and easy interpretable metabolite maps of the whole organ obtained without endorectal coil in clinically feasible acquisition times. We evaluated if a semi-LASER pulse sequence with gradient offset independent adiabaticity refocusing pulses (GOIA-sLASER) for volume selection can meet these requirements. MATERIALS AND METHODS: Thirteen patients with suspicion of prostate cancer and 1 patient known to have prostate cancer were examined at 3 T with a multichannel body-receive coil...
June 19, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28629785/-interest-using-3d-ultrasound-and-mri-fusion-biopsy-for-prostate-cancer-detection
#3
A Marien, A De Castro Abreu, I Gill, A Villers, O Ukimura
INTRODUCTION: The strategic therapy for prostate cancer depends on histo-pronostics data, which could be upgraded by obtaining targeted biopsies (TB) with MRI (magnetic resonance imagery) fusion 3D ultrasound. OBJECTIVES: To compare diagnostic yield of image fusion guided prostate biopsy using image fusion of multi-parametric MRI (mpMRI) with 3D-TRUS. MATERIALS AND METHODS: Between January 2010 and April 2013, 179 consecutive patients underwent outpatient TRUS biopsy using the real-time 3D TRUS tracking system (Urostation™)...
June 16, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28627396/prostate-mass-as-a-first-manifestation-of-myeloid-sarcoma-in-a-patient-with-an-occult-acute-myeloid-leukemia-a-case-report
#4
Natally Horvat, Pedro Sergio Brito Panizza, Frederico Perego Costa, Publio Cesar Cavalcanti Viana
Myeloid sarcoma (MS) with either primary or secondary prostate involvement is extremely rare. Its diagnostic is particularly challenging when prostate lesion precedes the systemic manifestation of a myeloproliferative disorder. We report such a case in a 44-year-old man with a prostate mass as a first manifestation of myeloid sarcoma associated with acute myeloid leukemia (AML). The diagnosis of lymphoproliferative disorder was suspected in the prostate magnetic resonance imaging (MRI) and MS was confirmed after transrectal ultrasound-guided prostate core biopsy...
June 13, 2017: Urology
https://www.readbyqxmd.com/read/28619734/-68-ga-psma11-pet-ct-in-newly-diagnosed-carcinoma-of-the-prostate-correlation-of-intraprostatic-psma-uptake-with-several-clinical-parameters
#5
Stefan A Koerber, Maximilian T Utzinger, Clemens Kratochwil, Claudia Kesch, Matthias Haefner, Sonja Katayama, Walter Mier, Andrei H Iagaru, Klaus Herfarth, Uwe Haberkorn, Juergen Debus, Frederik L Giesel
(68)Ga-prostate-specific membrane antigen (PSMA)-positron emission tomography (PET)/ computer tomography (CT) is a promising diagnostic tool for patients with prostate cancer. Our study evaluates standardized uptake values (SUV) in benign prostate tissue and malignant, intraprostatic tumor lesions and correlates results with several clinical parameters. Methods: One hundred and four men with newly diagnosed prostate carcinoma and no previous therapy were included in this study. Maximum SUV (SUVmax) was measured and correlated with biopsy findings and magnetic resonance imaging (MRI)...
June 15, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28618668/re-diagnostic-accuracy-of-multi-parametric-mri-and-trus-biopsy-in-prostate-cancer-promis-a-paired-validating-confirmatory-study
#6
Samir S Taneja
No abstract text is available yet for this article.
July 2017: Journal of Urology
https://www.readbyqxmd.com/read/28615794/deepinfer-open-source-deep-learning-deployment-toolkit-for-image-guided-therapy
#7
Alireza Mehrtash, Mehran Pesteie, Jorden Hetherington, Peter A Behringer, Tina Kapur, William M Wells, Robert Rohling, Andriy Fedorov, Purang Abolmaesumi
Deep learning models have outperformed some of the previous state-of-the-art approaches in medical image analysis. Instead of using hand-engineered features, deep models attempt to automatically extract hierarchical representations at multiple levels of abstraction from the data. Therefore, deep models are usually considered to be more flexible and robust solutions for image analysis problems compared to conventional computer vision models. They have demonstrated significant improvements in computer-aided diagnosis and automatic medical image analysis applied to such tasks as image segmentation, classification and registration...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28609110/monitoring-tumor-volume-in-patients-with-prostate-cancer-undergoing-active-surveillance-is-mri-apparent-diffusion-coefficient-indicative-of-tumor-growth
#8
Veronica A Morgan, Christopher Parker, Alison MacDonald, Karen Thomas, Nandita M deSouza
OBJECTIVE: The purpose of this study was to measure longitudinal change in tumor volume of the dominant intraprostatic lesion and determine whether baseline apparent diffusion coefficient (ADC) and change in ADC are indicative of tumor growth in patients with prostate cancer undergoing active surveillance. SUBJECTS AND METHODS: The study group included 151 men (mean age, 68.1 ± 7.4 [SD] years; range, 50-83 years) undergoing active surveillance with 3D whole prostate, zonal, and tumor volumetric findings documented at endorectal MRI examinations performed at two time points (median interval, 1...
June 13, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28607878/targeted-prostate-biopsy-using-68-gallium-psma-pet-ct-for-image-guidance
#9
Demetrios N Simopoulos, Shyam Natarajan, Tonye A Jones, Wolfgang P Fendler, Anthony E Sisk, Leonard S Marks
Prostate specific membrane antigen (PSMA) scanning is a sensitive method of prostate cancer detection. In a 71 y.o. man with a PSA of 49 (6%F), 4 negative MRI studies and 6 negative biopsies over an 8 year interval, a (68)Ga-PSMA PET/CT scan showed a PSMA-avid spot in the prostate. Using image fusion technology, the lesion was target-biopsied and Gleason 3 + 4 = 7 (cancer core length of 12 mm) was identified. This case may herald a new application for PSMA scanning and prostate cancer imaging.
September 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28589399/prostate-biopsy-in-active-surveillance-protocols-immediate-re-biopsy-and-timing-of-subsequent-biopsies
#10
REVIEW
Jonathan H Wang, Tracy M Downs, E Jason Abel, Kyle A Richards, David F Jarrard
PURPOSE OF REVIEW: This manuscript reviews contemporary literature regarding prostate cancer active surveillance (AS) protocols as well as other tools that may guide the management of biopsy frequency and assess the possibility of progression in low-risk prostate cancer. RECENT FINDINGS: There is no consensus regarding the timing of surveillance biopsies; however, an immediate repeat biopsy within 12 months of diagnosis for patients considering AS confirms patients who have favorable risk disease yet also identifies patients who were undersampled initially...
July 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28588732/trus-guided-transperineal-prostate-12-x-core-biopsy-with-template-for-the-diagnosis-of-prostate-cancer
#11
Gang Guo, Yong Xu, Xu Zhang
The objective of the present study was to explore the clinical value and safety of trans-rectal ultrasound (TRUS)-guided transperineal prostate 12+X core biopsy in the diagnosis of prostate cancer. Patients who received a TRUS-guided transperineal prostate biopsy for suspected prostate cancer at the General Hospital of The People's Liberation Army between September 2009 and May 2014 were retrospectively analyzed, this consisted of 1,300 patients. These patients were randomly divided into the 12+X core group or the standard 12-core group...
June 2017: Oncology Letters
https://www.readbyqxmd.com/read/28584167/severe-cushing-s-syndrome-due-to-small-cell-prostate-carcinoma-a-case-and-review-of-literature
#12
Marianne Elston, Veronica Crawford, Michael Swarbrick, Michael Dray, Michelle Head, John V Conaglen
Cushings syndrome (CS) due to ectopic adrenocorticotrophic hormone (ACTH) is associated with a variety of tumours most of which arise in the thorax or abdomen. Prostate carcinoma is a rare but important cause of rapidly progressive CS. To report a case of severe CS due to ACTH production from prostate neuroendocrine carcinoma and summarise previous published cases. A 71 year old man presented with profound hypokalaemia, oedema and new onset hypertension. He reported two weeks of weight gain, muscle weakness, labile mood and insomnia...
June 5, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28583630/evaluating-the-effect-of-rectal-distension-on-prostate-multiparametric-mri-image-quality
#13
Iztok Caglic, Nienke L Hansen, Rhys A Slough, Andrew J Patterson, Tristan Barrett
PURPOSE: To evaluate the effect of rectal distension on the quality of anatomical and functional prostate multiparametric (mp) MRI. MATERIALS AND METHODS: Multiparametric (mp) 3T-MRI images of 173 patients were independently evaluated by two radiologists in this retrospective study. Planimetry rectal volumes were derived and a subjective assessment of rectal distension was made using a 5-point Likert scale (1=no stool/gas, 5=large amount of stool/gas). Image quality of diffusion-weighted imaging (DWI) was evaluated using a 5-point Likert scale...
May 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28580659/ex-vivo-mri-evaluation-of-prostate-cancer-localization-and-margin-status-prediction-of-prostate-cancer-in-fresh-radical-prostatectomy-specimens
#14
Jan Heidkamp, Martijn Hoogenboom, Iringo E Kovacs, Andor Veltien, Arie Maat, J P Michiel Sedelaar, Christina A Hulsbergen-van de Kaa, Jurgen J Fütterer
PURPOSE: To investigate the ability of high field ex vivo magnetic resonance imaging (MRI) to localize prostate cancer (PCa) and to predict the margin status in fresh radical prostatectomy (RP) specimens using histology as the reference standard. MATERIALS AND METHODS: This Institutional Review Board (IRB)-approved study had written informed consent. Patients with biopsy-proved PCa and a diagnostic multiparametric 3T MRI examination of the prostate prior to undergoing RP were prospectively included...
June 5, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28570124/impact-of-the-prostate-imaging-reporting-and-data-system-version-2-on-mri-diagnosis-for-extracapsular-extension-of-prostate-cancer
#15
Yoh Matsuoka, Junichiro Ishioka, Hiroshi Tanaka, Tomo Kimura, Soichiro Yoshida, Kazutaka Saito, Yasuhisa Fujii, Kazunori Kihara
OBJECTIVE: The purpose of this study is to validate the Prostate Imaging Reporting and Data System, version 2 (PI-RADSv2), in assessing extracapsular extension (ECE), compared with PI-RADS, version 1 (PI-RADSv1). MATERIALS AND METHODS: A total of 210 patients with clinically localized prostate cancer underwent MRI and radical prostatectomy. Two readers independently interpreted the MR images. In PI-RADSv1, 5-point ECE risk scoring was used. In PI-RADSv2, ECE criteria included morphologic features and a tumor-capsule contact length (CL) greater than 10 mm...
June 1, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28570099/accuracy-and-interobserver-agreement-for-prostate-imaging-reporting-and-data-system-version-2-for-the-characterization-of-lesions-identified-on-multiparametric-mri-of-the-prostate
#16
Andrei S Purysko, Leonardo K Bittencourt, Jennifer A Bullen, Thomaz R Mostardeiro, Brian R Herts, Eric A Klein
OBJECTIVE: The objective of this study was to measure the accuracy and interobserver agreement of the Prostate Imaging Reporting and Data System, version 2 (PI-RADSv2), for the characterization of prostate lesions on multiparametric MRI. MATERIALS AND METHODS: This retrospective study included 170 men examined at a single institution between August 2014 and February 2015 on a 3-T MRI scanner. Study patients were found to have lesions concerning for prostate cancer that were targeted for MRI/transrectal ultrasound fusion biopsy...
June 1, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28562371/the-role-of-the-multiparametric-mri-in-the-diagnosis-of-prostate-cancer-in-biopsy-na%C3%A3-ve-men
#17
Adrian Rhudd, Jean McDonald, Mark Emberton, Veeru Kasivisvanathan
PURPOSE OF REVIEW: To review the role of prebiopsy multiparametric MRI in biopsy-naïve men for the detection of clinically significant prostate cancer. RECENT FINDINGS: Recent level 1 evidence shows that multiparametric MRI has high sensitivity and negative predictive value for the detection of clinically significant prostate cancer in biopsy-naïve men. Concurrent developments include important work in the standardization of MRI reporting. The low specificity and positive predictive value of MRI means that biopsy is still necessary following MRI...
May 29, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28559778/magnetic-resonance-imaging-in-hematospermia-does-it-increase-unnecessary-prostate-biopsy
#18
Luke A McGuinness, Samer Obeidat, Christopher Powell
INTRODUCTION: Hematospermia is an uncommon presentation of prostate cancer. Following the introduction of MRI for patients with hematospermia we evaluated its use and effect on prostate biopsy and cancer detection rates. MATERIALS AND METHODS: Analysis of patients attending our outpatient department over 2 years was undertaken. Diagnostic workup included digital rectal examination and PSA. Those with abnormal findings or persisting symptoms were offered prostate biopsy...
April 2017: Current Urology
https://www.readbyqxmd.com/read/28553585/dosimetric-and-radiobiological-evaluation-of-multiparametric-mri-guided-dose-painting-in-radiotherapy-of-prostate-cancer
#19
Iraj Abedi, Mohammad B Tavakkoli, Keyvan Jabbari, Alireza Amouheidari, Ghasem Yadegarfard
Radiotherapy is one of the treatment options for locally advanced prostate cancer; however, with standard radiation doses, it is not always very effective. One of the strategies to improve the efficiency of radiotherapy is increasing the dose. In this study, to increase tumor local control rates, a new radiotherapy method, known as dose painting (DP), was investigated. To compare 3-dimensional conformal radiotherapy (3D-CRT) and intensity modulated radiotherapy (IMRT) plans with DP for prostate cancer. Twenty-four consecutive patients with locally advanced prostate cancer who underwent an multiparametric-magnetic resonance imaging (MP-MRI) (T2w, diffusion weighted image, dynamic contrast enhancement, and MRS) scan before a diagnostic biopsy from September 2015 to April 2016 were invited to take part in this study...
April 2017: Journal of Medical Signals and Sensors
https://www.readbyqxmd.com/read/28552089/magnetic-resonance-imaging-guided-biopsies-may-improve-diagnosis-in-biopsy-naive-men-with-suspicion-of-prostate-cancer
#20
Mads Dochedahl Winther, Ingegerd Balslev, Lars Boesen, Vibeke Logager, Nis Noergaard, Karen-Cecilie Duus Thestrup, Henrik S Thomsen
INTRODUCTION: The purpose of this pilot study was to investigate whether a short prostate biparametric magnetic resonance imaging (bp-MRI) protocol provides a valuable diagnostic addition for biopsy guidance in biopsy-naive men with a suspicion of prostate cancer (PCa). METHODS: A total of 62 biopsy-naive patients referred to a systematic transrectal ultrasound biopsy (TRUS-bx) due to suspicion of PCa were prospectively enrolled. Bp-MRI was performed before biopsy...
May 2017: Danish Medical Journal
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