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Mri and prostate biopsy

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https://www.readbyqxmd.com/read/28440325/multiparametric-mri-ultrasound-fusion-guided-biopsy-decreases-detection-of-indolent-cancer-in-african-american-men
#1
M Kongnyuy, M M Siddiqui, A K George, A Muthigi, A Sidana, M Maruf, B Turkbey, P L Choyke, B J Wood, P A Pinto
BACKGROUND: Analysis of systematic 12-core biopsies (SBx) has shown that African-American (AA) men tend to harbor higher risk prostate cancer (PCa) at presentation relative to other races. Multiparametric magnetic resonance imaging (mpMRI) and MRI-ultrasound fusion-guided biopsy (FBx) have been shown to diagnose more intermediate- and high-risk PCa in the general population; however, the efficacy in AA remains largely uncharacterized. We aim to evaluate the utility of FBx in an AA patient cohort...
April 25, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28438627/atypical-small-acinar-proliferation-and-high-grade-prostatic-intraepithelial-neoplasia-in-the-era-of-multi-parametric-mri-a-contemporary-review
#2
REVIEW
Todd G Manning, Ernest Cheung, Marlon Perera, Daniel Christidis, Jonathan S O'Brien, Catherine Mitchell, Damien M Bolton, Nathan Lawrentschuk
Multiparametric Magnetic Resonance Imaging (mpMRI) has added to the armamentarium for the diagnosis and surveillance for organ confined prostate cancer. Atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are premalignant prostatic lesions. The management of such lesions remains contentious, and the addition of mpMRI introduces further uncertainty given its ability to pick up indolent lesions and its use in targeted biopsy. We aimed to perform a comprehensive review of current evidence regarding ASAP, HGPIN and mpMRI to ascertain a consensus for a current management algorithm...
April 21, 2017: Urology
https://www.readbyqxmd.com/read/28424829/-mri-of-the-prostate
#3
D Nörenberg, O Solyanik, B Schlenker, G Magistro, B Ertl-Wagner, D A Clevert, C Stief, M F Reiser, M D'Anastasi
New clinical and technological advances in the field of magnetic resonance imaging (MRI) and targeted image-guided biopsy techniques have significantly improved the detection, localization and staging as well as active surveillance of prostate cancer in recent years. Multiparametric MRI (mpMRI) is currently the main imaging technique for the detection, characterization and diagnostics of metastasizing prostate cancer and is of high diagnostic importance for local staging within the framework of the detection of prostate cancer...
April 19, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28422738/peripheral-zone-volume-ratio-pz-ratio-is-relevant-with-biopsy-results-and-can-increase-the-accuracy-of-current-diagnostic-modality
#4
Yifan Chang, Rui Chen, Qingsong Yang, Xu Gao, Chuanliang Xu, Jianping Lu, Yinghao Sun
The current diagnostic modality of prostate cancer based on prostate specific antigen (PSA) and systematic biopsy is far from ideal in terms of over-diagnosing indolent prostate cancer and missing significant ones. Thus we integrated the peripheral zone volume ratio (PZ-ratio) for diagnostic refinement. This retrospective study included 247 consecutive patients who underwent initial transrectal ultrasound-guided systematic prostate biopsy from April 2014 to November 2015. Prostate volume was determined by semi-automatic contour on axial T2 weighted magnetic resonance imaging (MRI)...
March 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/28418690/pi-rads-version-2-detection-of-clinically-significant-cancer-in-patients-with-biopsy-gleason-score-6-prostate-cancer
#5
Ji Won Seo, Su-Jin Shin, Young Taik Oh, Dae Chul Jung, Nam Hoon Cho, Young Deuk Choi, Sung Yoon Park
OBJECTIVE: The purpose of this study was to analyze the utility of the Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) in the detection of a clinically significant cancers in patients with prostate cancers with a biopsy Gleason score of 6. MATERIALS AND METHODS: A group of 182 consecutively registered patients with biopsy-proven prostate cancer with a Gleason score of 6 underwent MRI and radical prostatectomy. Clinically significant cancer was surgically defined as Gleason score of 7 or greater, tumor volume of 0...
April 18, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28409355/percutaneous-mr-guided-focal-cryoablation-for-recurrent-prostate-cancer-following-radiation-therapy-retrospective-analysis-of-iceball-margins-and-outcomes
#6
Christiaan G Overduin, Sjoerd F M Jenniskens, J P Michiel Sedelaar, Joyce G R Bomers, Jurgen J Fütterer
OBJECTIVES: To evaluate iceball margins after magnetic resonance (MR)-guided focal salvage prostate cryoablation and determine the correlation with local outcome. METHODS: A retrospective review was performed on 47 patients that underwent percutaneous MR-guided focal cryoablation for biopsy-proven locally recurrent prostate cancer after primary radiotherapy. Preprocedural diagnostic and intraprocedural MR images were analysed to derive three-directional iceball margins...
April 13, 2017: European Radiology
https://www.readbyqxmd.com/read/28400169/combined-clinical-parameters-and-multiparametric-magnetic-resonance-imaging-for-advanced-risk-modeling-of-prostate-cancer-patient-tailored-risk-stratification-can-reduce-unnecessary-biopsies
#7
Jan Philipp Radtke, Manuel Wiesenfarth, Claudia Kesch, Martin T Freitag, Celine D Alt, Kamil Celik, Florian Distler, Wilfried Roth, Kathrin Wieczorek, Christian Stock, Stefan Duensing, Matthias C Roethke, Dogu Teber, Heinz-Peter Schlemmer, Markus Hohenfellner, David Bonekamp, Boris A Hadaschik
BACKGROUND: Multiparametric magnetic resonance imaging (mpMRI) is gaining widespread acceptance in prostate cancer (PC) diagnosis and improves significant PC (sPC; Gleason score≥3+4) detection. Decision making based on European Randomised Study of Screening for PC (ERSPC) risk-calculator (RC) parameters may overcome prostate-specific antigen (PSA) limitations. OBJECTIVE: We added pre-biopsy mpMRI to ERSPC-RC parameters and developed risk models (RMs) to predict individual sPC risk for biopsy-naïve men and men after previous biopsy...
April 8, 2017: European Urology
https://www.readbyqxmd.com/read/28396920/the-role-of-whole-lesion-apparent-diffusion-coefficient-analysis-for-predicting-outcomes-of-prostate-cancer-patients-on-active-surveillance
#8
Tsutomu Tamada, Hasan Dani, Samir S Taneja, Andrew B Rosenkrantz
PURPOSE: To explore the role of whole-lesion apparent diffusion coefficient (ADC) analysis for predicting outcomes in prostate cancer patients on active surveillance. METHODS: This study included 72 prostate cancer patients who underwent MRI-ultrasound fusion-targeted biopsy at the initiation of active surveillance, had a visible MRI lesion in the region of tumor on biopsy, and underwent 3T baseline and follow-up MRI examinations separated by at least one year. Thirty of the patients also underwent an additional MRI-ultrasound fusion-targeted biopsy after the follow-up MRI...
April 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28396184/focal-laser-ablation-of-prostate-cancer-feasibility-of-mri-us-fusion-for-guidance
#9
Shyam Natarajan, Tonye A Jones, Alan M Priester, Rory Geoghegan, Patricia Lieu, Merdie Delfin, Ely Felker, Daniel J A Margolis, Anthony Sisk, Allan Pantuck, Warren Grundfest, Leonard S Marks
PURPOSE: Focal laser ablation (FLA) is a potential treatment for some men with prostate cancer (CaP). As currently practiced, FLA is performed by radiologists in a MRI unit (in-bore). We evaluated the safety and feasibility of performing FLA in a urology clinic (out-of-bore), using magnetic resonance imaging-ultrasound (MRI/US) fusion for guidance. MATERIALS AND METHODS: 11 men with intermediate risk CaP were enrolled in this prospective, IRB-approved pilot study...
April 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28393492/reliability-of-negative-multiparametric-mri-of-the-prostate-can-we-avoid-the-biopsy-not-yet
#10
EDITORIAL
Mark Frydenberg
No abstract text is available yet for this article.
May 2017: BJU International
https://www.readbyqxmd.com/read/28391284/gleason-score-within-prostate-abnormal-areas-defined-by-multiparametric-magnetic-resonance-imaging-did-not-vary-according-to-the-pirads-score
#11
Hakim Slaoui, Yann Neuzillet, Tarek Ghoneim, Mathieu Rouanne, Abdelali Abdou, Pierre Marie Lugagne-Delpon, Antoine Scherrer, Camelia Radulescu, Christian Delancourt, Vincent Molinié, Thierry Lebret
BACKGROUND: We aim to correlate multiparametric magnetic resonance imaging (mpMRI) of the prostate reporting (Prostate Imaging Reporting and Data System [PI-RADS] version 2) with the Gleason score into both radical prostatectomy (RP) specimen and MRI fusion-targeted biopsies (FTB). METHODS: mpMRI of 74 patients who underwent an RP after FTB were retrospectively reviewed. The Gleason score distribution was compared according to the PI-RADS score using the Kruskal-Wallis test...
April 8, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28385253/prostate-cancer-state-of-the-art-imaging-and-focal-treatment
#12
REVIEW
D A Woodrum, A Kawashima, K R Gorny, L A Mynderse
In 2016, it is estimated 180,890 men are newly diagnosed with prostate cancer and 3,306,760 men live with prostate cancer in the United States. The introduction of multiparametric (mp) magnetic resonance imaging (MRI) of the prostate, standardised interpretation guidelines such as Prostate Imaging Reporting and Data System (PI-RADS version 2), and MRI-based targeted biopsy has improved detection of clinically significant prostate cancer. Accurate risk stratification (Gleason grade/score and tumour stage) using imaging and image-guided targeted biopsy has become critical for the management of patients with prostate cancer...
April 3, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28381220/the-prostate-cancer-detection-rates-of-ceus-targeted-versus-mri-targeted-versus-systematic-trus-guided-biopsies-in-biopsy-na%C3%A3-ve-men-a-prospective-comparative-clinical-trial-using-the-same-patients
#13
A W Postema, M J V Scheltema, C K Mannaerts, R J G Van Sloun, T Idzenga, M Mischi, M R E Engelbrecht, J J M C H De la Rosette, H Wijkstra
BACKGROUND: The current standard for Prostate Cancer (PCa) detection in biopsy-naïve men consists of 10-12 systematic biopsies under ultrasound guidance. This approach leads to underdiagnosis and undergrading of significant PCa while insignificant PCa may be overdiagnosed. The recent developments in MRI and Contrast Enhanced Ultrasound (CEUS) imaging have sparked an increasing interest in PCa imaging with the ultimate goal of replacing these "blind" systematic biopsies with reliable imaging-based targeted biopsies...
April 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28377946/assessing-the-validity-of-prostate-imaging-reporting-and-data-system-version-2-pi-rads-v2-scoring-system-in-diagnosis-of-peripheral-zone-prostate-cancer
#14
Eman F Dola, Osama L Nakhla, Eman A Sh Genidi
THE PURPOSE: Assessing the accuracy of multi parametric magnetic resonance (mp-MRI) after application of PI-RADS V2 for diagnosis of prostate cancer as comparison to pathological results of trans rectal ultra-sound (TRUS) guided biopsy. PATIENTS AND METHODS: 138 prostatic lesions in 23 patients were retrospectively assessed and analyzed with Trans rectal ultra-sound (TRUS) guided biopsy results. Those patients underwent multi parametric magnetic resonance (mp-MRI) with application of PI-RADS V2 reporting system...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/28373135/the-value-of-psa-density-in-combination-with-pi-rads-for-the-accuracy-of-prostate-cancer-prediction
#15
Florian A Distler, Jan P Radtke, David Bonekamp, Claudia Kesch, Heinz-Peter Schlemmer, Kathrin Wieczorek, Marietta Kirchner, Sascha Pahernik, Markus Hohenfellner, Boris A Hadaschik
PURPOSE: Multiparametric MRI (mpMRI) has an emerging role in prostate cancer (PC) diagnostics. In addition, clinical information are reliable predictors for significant PC (sPC). We analyzed if the negative predictive value (NPV) of mpMRI to rule out sPC could be improved by using clinical factors, especially prostate specific antigen (PSA)-density. METHODS: 1040 consecutive men with suspicion of PC underwent mpMRI first, followed by transperineal systematic and MRI/TRUS-fusion-guided biopsy...
March 31, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28373133/prospective-evaluation-of-prostate-imaging-reporting-and-data-system-version-2-using-the-international-society-of-urological-pathology-prostate-cancer-grade-group-system
#16
Sherif Mehralivand, Sandra Bednarova, Joanna H Shih, Francesca V Mertan, Sonia Gaur, Maria J Merino, Bradford J Wood, Peter A Pinto, Peter L Choyke, Baris Turkbey
PURPOSE: The Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2) scoring system, introduced in 2015, is based on expert consensus. In the same time; frame, a new pathologic scoring system for prostate cancer was introduced by the International Society of Urological Pathology (ISUP). Our goal was to prospectively evaluate the cancer detection rates for each PI-RADSv2 category and compare to ISUP group scores in patients undergoing systematic biopsy and MRI/transrectal ultrasound fusion-guided biopsy...
March 31, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28351193/measurement-of-serum-isoform-2-propsa-derivatives-shows-superior-accuracy-to-magnetic-resonance-imaging-in-the-diagnosis-of-prostate-cancer-in-patients-with-a-total-prostate-specific-antigen-level-of-2-10%C3%A2-ng-ml
#17
Kazuhiro Furuya, Takashi Kawahara, Masaki Narahara, Takashi Tokita, Sachi Fukui, Masashi Imano, Taku Mitome, Yusuke Ito, Koji Izumi, Kimito Osaka, Yumiko Yokomizo, Narihiko Hayashi, Hisashi Hasumi, Shintaro Nawata, Tsuyoshi Kawano, Masahiro Yao, Hiroji Uemura
OBJECTIVE: More accurate diagnostic procedures for prostate cancer are needed to avoid unnecessary biopsy due to the low specificity of prostate-specific antigen (PSA). Recent studies showed that the percentage of serum isoform [-2]proPSA (p2PSA) to free PSA (%p2PSA), the Prostate Health Index (PHI) and magnetic resonance imaging (MRI) were more accurate than PSA. The aim of this study was to test the accuracy of %p2PSA, PHI and MRI in discriminating patients with and without prostate cancer...
March 29, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28350925/avoiding-unnecessary-prostate-biopsies-with-mri
#18
Anita Slomski
No abstract text is available yet for this article.
March 28, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28350785/the-picture-study-diagnostic-accuracy-of-multiparametric-mri-in-men-requiring-a-repeat-prostate-biopsy
#19
Lucy A M Simmons, Abi Kanthabalan, Manit Arya, Tim Briggs, Dean Barratt, Susan C Charman, Alex Freeman, James Gelister, David Hawkes, Yipeng Hu, Charles Jameson, Neil McCartan, Caroline M Moore, Shonit Punwani, Navin Ramachandran, Jan van der Meulen, Mark Emberton, Hashim U Ahmed
BACKGROUND: Transrectal prostate biopsy has limited diagnostic accuracy. Prostate Imaging Compared to Transperineal Ultrasound-guided biopsy for significant prostate cancer Risk Evaluation (PICTURE) was a paired-cohort confirmatory study designed to assess diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) in men requiring a repeat biopsy. METHODS: All underwent 3 T mpMRI and transperineal template prostate mapping biopsies (TTPM biopsies)...
April 25, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28349507/transfer-learning-from-rf-to-b-mode-temporal-enhanced-ultrasound-features-for-prostate-cancer-detection
#20
Shekoofeh Azizi, Parvin Mousavi, Pingkun Yan, Amir Tahmasebi, Jin Tae Kwak, Sheng Xu, Baris Turkbey, Peter Choyke, Peter Pinto, Bradford Wood, Purang Abolmaesumi
PURPOSE: We present a method for prostate cancer (PCa) detection using temporal enhanced ultrasound (TeUS) data obtained either from radiofrequency (RF) ultrasound signals or B-mode images. METHODS: For the first time, we demonstrate that by applying domain adaptation and transfer learning methods, a tissue classification model trained on TeUS RF data (source domain) can be deployed for classification using TeUS B-mode data alone (target domain), where both data are obtained on the same ultrasound scanner...
March 27, 2017: International Journal of Computer Assisted Radiology and Surgery
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