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Mri and prostate biopsy

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https://www.readbyqxmd.com/read/29792972/association-between-early-confirmatory-testing-and-the-adoption-of-active-surveillance-for-men-with-favorable-risk-prostate-cancer
#1
Deborah R Kaye, Ji Qi, Todd M Morgan, Susan Linsell, Brian R Lane, James E Montie, Michael L Cher, David C Miller
OBJECTIVE: To examine the relationship between the use and results of early confirmatory testing and persistence on active surveillance (AS). METHODS: We identified all men in the MUSIC registry diagnosed with favorable-risk prostate cancer from 01/2016-02/2017. We next examined trends in the use of early confirmatory test(s), defined as repeat biopsy, prostate MRI and/or molecular classifiers obtained within 6-months of the initial cancer diagnosis, in patients with favorable-risk prostate cancer...
May 21, 2018: Urology
https://www.readbyqxmd.com/read/29789909/fast-3-t-mr-guided-transrectal-prostate-biopsy-using-an-in-room-tablet-device-for-needle-guide-alignment-a-feasibility-study
#2
Christiaan G Overduin, Jan Heidkamp, Eva Rothgang, Jelle O Barentsz, Frank de Lange, Jurgen J Fütterer
OBJECTIVES: To assess the feasibility of adding a tablet device inside the scanner room to assist needle-guide alignment during magnetic resonance (MR)-guided transrectal prostate biopsy. METHODS: Twenty patients with one cancer-suspicious region (CSR) with PI-RADS score ≥ 4 on diagnostic multiparametric MRI were prospectively enrolled. Two orthogonal scan planes of an MR fluoroscopy sequence (~3 images/s) were aligned to the CSR and needle-guide pivoting point...
May 22, 2018: European Radiology
https://www.readbyqxmd.com/read/29789235/-pathology-findings-after-radical-prostatectomy-for-prostate-cancer-in-patients-eligible-for-active-surveillance-contribution-of-multiparametric-mri-to-treatment-decision
#3
A Martin-Malburet, G Marcq, X Leroy, P Guiffart, J-C Fantoni, V Flamand, A Villers, P Puech, A Ouzzane
OBJECTIVES: To analyze, in patients with prostate cancer (PC) potentially eligible for active surveillance (AS), whether multiparametric-MRI (mp-MRI) predicts presence of clinically significant cancer on radical prostatectomy (RP) specimen. METHODS: We identified 77 men with PC eligible for AS (PSA≤15ng/mL, stage≤T2a, Gleason score≤6, up to 3 positive cores, maximal cancer core length≤5mm) who underwent RP between 01/2008 and 08/2015. All patients had prebiopsy mp-MRI followed by systematic±targeted biopsies...
May 20, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29786588/-infectious-complications-of-prostate-biopsy
#4
Marcin Łykowski, Bartosz Dybowski, Sławomir Poletajew, Tomasz Piecha, Piotr Radziszewski
Prostate cancer is the second most common malignancy in men in Poland. Prostate biopsy remains the gold standard for diagnosis. Every year, the number of procedures is increasing, so knowledge of possible complications is becoming crucial. Over time, a continuous increase in infectious complications of prostate biopsy is observed, so it is important to identify risk factors and preventive methods. Antibiotic prophylaxis is mandatory for prostate biopsy. Simultaneously, complications after prostate biopsy affect as many as 90% of patients, including up to 17% of infective complications...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29785491/follow-up-of-negative-mri-targeted-prostate-biopsies-when-are-we-missing-cancer
#5
Samuel A Gold, Graham R Hale, Jonathan B Bloom, Clayton P Smith, Kareem N Rayn, Vladimir Valera, Bradford J Wood, Peter L Choyke, Baris Turkbey, Peter A Pinto
INTRODUCTION: Multiparametric magnetic resonance imaging (mpMRI) has improved clinicians' ability to detect clinically significant prostate cancer (csPCa). Combining or fusing these images with the real-time imaging of transrectal ultrasound (TRUS) allows urologists to better sample lesions with a targeted biopsy (Tbx) leading to the detection of greater rates of csPCa and decreased rates of low-risk PCa. In this review, we evaluate the technical aspects of the mpMRI-guided Tbx procedure to identify possible sources of error and provide clinical context to a negative Tbx...
May 21, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29785385/malakoplakia-of-the-prostate-diagnosed-on-multiparametric-mri-ultrasound-fusion-guided-biopsy-a-case-report-and-review-of-the-literature
#6
Maria C Velasquez, Paul J Taylor Smith, Nachiketh Soodana Prakash, Bruce Kava, Oleksandr N Kryvenko, Rosa Castillo-Acosta, Leonardo Kayat Bittencourt, Mark L Gonzalgo, Chad Ritch, Dipen J Parekh, Sanoj Punnen
No abstract text is available yet for this article.
May 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29772101/computer-aided-diagnosis-of-prostate-cancer-on-magnetic-resonance-imaging-using-a-convolutional-neural-network-algorithm
#7
Junichiro Ishioka, Yoh Matsuoka, Sho Uehara, Yosuke Yasuda, Toshiki Kijima, Soichiro Yoshida, Minato Yokoyama, Kazutaka Saito, Kazunori Kihara, Noboru Numao, Tomo Kimura, Kosei Kudo, Itsuo Kumazawa, Yasuhisa Fujii
OBJECTIVES: To develop a computer-aided diagnosis (CAD) algorithm with a deep learning architecture for detecting prostate cancer on magnetic resonance imaging (MRI) to promote global standardization and diminish variation in the interpretation of prostate MRI. PATIENTS AND METHODS: We retrospectively reviewed data from 335 patients with a prostate specific antigen level of less than 20 ng/ml who underwent MRI and extended systematic prostate biopsy with or without MRI-targeted biopsy...
May 17, 2018: BJU International
https://www.readbyqxmd.com/read/29770762/mri-us-fusion-guided-prostate-biopsy-allows-for-equivalent-cancer-detection-with-significantly-fewer-needle-cores-in-biopsy-naive-men
#8
Vidhush K Yarlagadda, Win Shun Lai, Jennifer B Gordetsky, Kristin K Porter, Jeffrey W Nix, John V Thomas, Soroush Rais-Bahrami
PURPOSE: We aimed to investigate the efficiency and cancer detection of magnetic resonance imaging (MRI) / ultrasonography (US) fusion-guided prostate biopsy in a cohort of biopsy-naive men compared with standard-of-care systematic extended sextant transrectal ultrasonography (TRUS)-guided biopsy. METHODS: From 2014 to 2016, 72 biopsy-naive men referred for initial prostate cancer evaluation who underwent MRI of the prostate were prospectively evaluated. Retrospective review was performed on 69 patients with lesions suspicious for malignancy who underwent MRI/US fusion-guided biopsy in addition to systematic extended sextant biopsy...
May 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29770311/-super-active-surveillance-mri-ultrasound-fusion-biopsy-and-ablation-for-less-invasive-management-of-prostate-cancer
#9
REVIEW
Jonathan B Bloom, Samuel A Gold, Graham R Hale, Kareem N Rayn, Vikram K Sabarwal, Ivane Bakhutashvili, Vladimir Valera, Baris Turkbey, Peter A Pinto, Bradford J Wood
Multiparametric magnetic resonance imaging (mpMRI) of the prostate has allowed clinicians to better visualize and target suspicious lesions during biopsy. Targeted prostate biopsies give a more accurate representation of the true cancer volume and stage so that appropriate treatment or active surveillance can be selected. Advances in technology have led to the development of MRI and ultrasound fusion platforms used for targeted biopsies, monitoring cancer progression, and more recently for the application of focal therapy...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29761076/synchronous-bone-metastasis-from-multiple-myeloma-and-prostate-adenocarcinoma-as-initial-presentation-of-coexistent-malignancies
#10
Diego Andres Adrianzen Herrera, Shlomit Goldberg-Stein, Alexander Sankin, Judy Sarungbam, Janaki Sharma, Benjamin A Gartrell
The radiographic appearance of bone metastases is usually determined by tumor histology and can be osteolytic, osteoblastic, or mixed. We present a patient with coexistent bone metastasis from multiple myeloma and prostate adenocarcinoma who exhibited synchronous bone involvement of both histologies within the same bone lesion, a rare phenomenon that has not been previously reported and led to atypical radiographic findings. The radiograph of a 71-year-old man with thigh swelling and pain demonstrated a lytic femoral lesion...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29753548/fusion-prostate-biopsy-outperforms-12-core-systematic-prostate-biopsy-in-patients-with-prior-negative-systematic-biopsy-a-multi-institutional-analysis
#11
Abhinav Sidana, Matthew J Watson, Arvin K George, Ardeshir R Rastinehad, Srinivas Vourganti, Soroush Rais-Bahrami, Akhil Muthigi, Mahir Maruf, Jennifer B Gordetsky, Jeffrey W Nix, Maria J Merino, Baris Turkbey, Peter L Choyke, Bradford J Wood, Peter A Pinto
INTRODUCTION AND OBJECTIVES: Patients with persistently elevated prostate specific antigen (PSA) and prior negative 12-core TRUS prostate biopsy (or biopsies) (systematic biopsy-SBx) are a diagnostic challenge. Repeat SBx or saturation biopsy in this cohort has been shown to have an even lower yield. The aim of our study is to compare the prostate cancer yield of magnetic resonance imaging (MRI) fusion biopsy (FBx) to SBx in a multi-institutional cohort comprised of patients with prior negative biopsies...
May 9, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29742600/incidental-detection-of-meningioma-by-18f-fmau-pet-ct-in-a-patient-with-suspected-prostate-cancer
#12
Bino Varghese, Erik Velez, Bhushan Desai, Hossein Jadvar
We report on an incidental detection of a meningioma on [F]-2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (F-FMAU) PET/CT scan that was performed during a prospective investigation of F-FMAU PET/CT for targeted biopsy of potential sites of tumor in men with suspected prostate cancer based on elevated prostate-specific antigen level. Neither prostate multiparamteric MRI nor F-FMAU PET/CT localized small volume Gleason 3 + 3 tumor deposits. However, an incidental focal high accumulation of F-FMAU was observed in high right parietal lobe that displayed characteristics of a meningioma on a subsequent brain MRI...
May 7, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29742381/mri-targeted-versus-ultrasonography-guided-biopsy-for-suspected-prostate-cancer
#13
EDITORIAL
Michael J Barry, Andrew B Rosenkrantz
New England Journal of Medicine, Volume 378, Issue 19, Page 1835-1836, May 2018.
May 10, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29740666/-paradigm-shift-in-urology-prostate-cancer-diagnosis-using-mri-targeted-or-standard-transrectal-ultrasonography-guided-biopsy
#14
B Hadaschik
No abstract text is available yet for this article.
May 8, 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29733838/validation-of-pi-rads-version-2-for-the-detection-of-prostate-cancer
#15
Sebastian L Hofbauer, Beatrice Kittner, Andreas Maxeiner, Robin Heckmann, Maximillian Reimann, Laura Wiemer, Patrick Asbach, Matthias Haas, Tobias Penzkofer, Carsten Stephan, Frank Friedersdorff, Florian Fuller, Kurt Miller, Hannes Cash
PURPOSE: The second version of the Prostate Imaging Reporting and Data System (PI-RADSv2) was introduced in 2015 to standardize the interpretation and reporting of multiparametric prostate magnetic resonance imaging (mpMRI). Recently, low cancer detection rates (CDR) for PI-RADSv2 category 4 lesions were reported. Therefore the aim of the study was to evaluate the CDR of PI-RADSv2 in a large prospective cohort. METHODS: The study included 704 consecutive men with primary or prior negative biopsies who underwent MRI/ultrasound fusion-guided targeted biopsy (TB) and 10-core systematic prostate biopsy (SB) between September 2015 and May 2017...
May 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29733837/multiparametric-mri-ultrasound-fusion-prostate-biopsy-are-two-biopsy-cores-per-mri-lesion-required
#16
P Dimitroulis, R Rabenalt, A Nini, A Hiester, I Esposito, L Schimmöller, G Antoch, P Albers, C Arsov
PURPOSE: For multiparametric MRI/Ultrasound fusion prostate biopsy (FUSBx) the number of taken biopsy cores is arbitrary established by urologists. Moreover, general consensus on the number of biopsy cores to be obtained from a single MRI-lesion is lacking. Therefore, we aimed to evaluate the feasibility of obtaining only one biopsy core per MRI-lesion. MATERIALS AND METHODS: We retrospectively evaluated 2128 biopsy cores of 1064 prostatic lesions (two cores per lesion) in 418 patients regarding prostate cancer (PCa) detection (histology) and Gleason score (GS) of the first biopsy core (FBC) compared to the second biopsy core (SBC)...
May 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29732279/racial-disparities-and-considerations-for-active-surveillance-of-prostate-cancer
#17
REVIEW
Song Jiang, Vikram Narayan, Christopher Warlick
Active surveillance (AS) for the management of low-risk prostate cancer has been increasing and in the general population appears safe, allowing for a reduction in the harms of prostate cancer screening such as overtreatment. African-American (AA) men have overall worse outcomes from prostate cancer compared to Caucasian-American (CA) men for a variety of socioeconomic, cultural and possibly biologic reasons, thus complicating the use of AS in this population. Strategies for optimizing care and mitigating risk in this population include pursuing close surveillance with steadfast patient compliance, the use of multiparametric MRI with targeted biopsies including the anterior prostate to reduce the risk of undersampling, as well as a judicious and thoughtful incorporation of novel molecular biomarkers for risk stratification...
April 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29732203/is-magnetic-resonance-imaging-helpful-in-detecting-significant-prostate-cancer-in-patients-with-haematospermia-normal-prostate-specific-antigen-level-and-digital-rectal-examination-a-single-institution-observational-and-retrospective-study-in-a-united-kingdom
#18
Rafał Turo, Seth Horsu, Andra Calinciuc, Michal Smolski, Helene Thygesen, Gerard Doyle, Dev Mohan Gulur, Sanjay Das, Bo Pettersson, Ninaad Awsare
Introduction: Haematospermia is an uncommon clinical condition that may be associated with prostate cancer. The optimal investigation of haematospermia is unknown. The aim of this study was to investigate haematospermia as a presenting symptom of significant pathology and to assess the diagnostic value of magnetic resonance imaging (MRI). Material and methods: Patient and treatment parameters were collected from a practice cohort of men referred to a urology center presenting with haematospermia...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29730256/the-role-of-imaging-in-prostate-cancer-care-pathway-novel-approaches-to-urologic-management-challenges-along-ten-imaging-touch-points
#19
REVIEW
Qian Li, Feixiang Xiang, Xueying Lin, Joseph R Grajo, Long Yang, Yufeng Xu, Yu Duan, Urvi Vyas, Mukesh Harisinghani, Umar Mahmood, Anthony E Samir
We map out a typical prostate cancer care pathway through discussion of updates on modern imaging. Multiparametric MRI (mpMRI) is the most sensitive and specific imaging tool for diagnosis and local staging, transrectal ultrasound remains the most widely used technique for prostate biopsy guidance, CT and bone scan are useful in initial staging and recurrence detection. Novel imaging techniques in ultrasound elastography and mpMRI allow for increased lesion detection sensitivity and have the potential to enhance biopsy, while the development of new PET radiotracers has great promise for improved detection of local and metastatic disease in patients with biochemical recurrence...
May 3, 2018: Urology
https://www.readbyqxmd.com/read/29725743/3t-multiparametric-mr-imaging-piradsv2-based-detection-of-index-prostate-cancer-lesions-in-the-transition-zone-and-the-peripheral-zone-using-whole-mount-histopathology-as-reference-standard
#20
Nazanin Hajarol Asvadi, Sohrab Afshari Mirak, Amirhossein Mohammadian Bajgiran, Pooria Khoshnoodi, Pornphan Wibulpolprasert, Daniel Margolis, Anthony Sisk, Robert E Reiter, Steven S Raman
PURPOSE: To evaluate 3T mpMRI characteristics of transition zone and peripheral zone index prostate cancer lesions stratified by Gleason Score and PI-RADSv2 with whole mount histopathology correlation. METHODS: An institution review board-approved, HIPAA-compliant single-arm observational study of 425 consecutive men with 3T mpMRI prior to radical prostatectomy from December 2009 to October 2016 was performed. A genitourinary radiologist and a genitourinary pathologist matched all lesions detected on whole mount histopathology with lesions concordant for size and location on 3T mpMRI...
May 3, 2018: Abdominal Radiology
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