keyword
MENU ▼
Read by QxMD icon Read
search

Iron deficient

keyword
https://www.readbyqxmd.com/read/27933573/-efficacy-of-an-iron-retard-preparation-in-patients-with-iron-deficiency-anemia
#1
Peter Nielsen, Rosemarie Kongi, Roland Fischer
OBJECTIVE: To study the therapeutic efficacy of an oral iron retard preparation in patients with iron deficiency anemia. METHODS: In an investigator-initiated open study, 28 patients with iron deficiency anemia were treated with an iron sulfate sustained-release preparation (80 mg iron ions per tablet). The bioavailability was determined from the increase in the haemoglobin value under therapy and the measured blood loss. For the quantification of individual blood losses, a (59)Fe labeling method was used and the (59)Fe whole body retention in the observation period was measured with a whole body counter...
December 2016: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/27933069/accumulation-and-secretion-of-coumarinolignans-and-other-coumarins-in-arabidopsis-thaliana-roots-in-response-to-iron-deficiency-at-high-ph
#2
Patricia Sisó-Terraza, Adrián Luis-Villarroya, Pierre Fourcroy, Jean-François Briat, Anunciación Abadía, Frédéric Gaymard, Javier Abadía, Ana Álvarez-Fernández
Root secretion of coumarin-phenolic type compounds has been recently shown to be related to Arabidopsis thaliana tolerance to Fe deficiency at high pH. Previous studies revealed the identity of a few simple coumarins occurring in roots and exudates of Fe-deficient A. thaliana plants, and left open the possible existence of other unknown phenolics. We used HPLC-UV/VIS/ESI-MS(TOF), HPLC/ESI-MS(ion trap) and HPLC/ESI-MS(Q-TOF) to characterize (identify and quantify) phenolic-type compounds accumulated in roots or secreted into the nutrient solution of A...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27933059/formation-of-neutrophil-extracellular-traps-under-low-oxygen-level
#3
Katja Branitzki-Heinemann, Helene Möllerherm, Lena Völlger, Diab M Husein, Nicole de Buhr, Stefanie Blodkamp, Friederike Reuner, Graham Brogden, Hassan Y Naim, Maren von Köckritz-Blickwede
Since their discovery, neutrophil extracellular traps (NETs) have been characterized as a fundamental host innate immune defense mechanism. Conversely, excessive NET-release may have a variety of detrimental consequences for the host. A fine balance between NET formation and elimination is necessary to sustain a protective effect during an infectious challenge. Our own recently published data revealed that stabilization of hypoxia-inducible factor 1α (HIF-1α) by the iron chelating HIF-1α-agonist desferoxamine or AKB-4924 enhanced the release of phagocyte extracellular traps...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27932689/hiatus-hernia-presenting-as-resistant-iron-deficiency-anaemia-in-a-child
#4
Mohemmed Ajij, Shambhavi, Shalu Gupta
No abstract text is available yet for this article.
January 2017: Tropical Doctor
https://www.readbyqxmd.com/read/27932449/oral-iron-treatment-response-and-predictors-in-anaemic-adolescents-and-adults-with-ibd-a-prospective-controlled-open-label-trial
#5
David S Rampton, James R Goodhand, Neerav M Joshi, Abu-Bakarr Karim, Yasmine Koodun, Farah M Barakat, Lucia Macken, Douglas G Ward, Tariq H Iqbal, Jenny Epstein, John M Fell, Ian R Sanderson
BACKGROUND: Because of previous concerns about the efficacy and safety of oral iron for treating iron deficiency anaemia in IBD, particularly in young people, we compared the effects of ferrous sulphate on haemoglobin response, disease activity and psychometric scores in adolescents and adults with IBD. We also assessed the relation of baseline serum hepcidin to haemoglobin response. METHODS: We undertook a prospective, open-label, 6-week non-inferiority trial of the effects of ferrous sulphate 200mg twice daily on haemoglobin, iron status, hepcidin, disease activity (Harvey-Bradshaw Index, Simple Colitis Clinical Activity Index, C-reactive protein (CRP), faecal calprotectin and psychometric scores in 45 adolescents (age 13-18 years) and 43 adults (>18 years)...
December 7, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27929101/hookworm-infection
#6
Alex Loukas, Peter J Hotez, David Diemert, Maria Yazdanbakhsh, James S McCarthy, Rodrigo Correa-Oliveira, John Croese, Jeffrey M Bethony
Hookworms are soil-transmitted nematode parasites that can reside for many years in the small intestine of their human hosts; Necator americanus is the predominant infecting species. Adult worms feed on the blood of a host and can cause iron deficiency anaemia, especially in high-risk populations (children and women of childbearing age). Almost 500 million people in developing tropical countries are infected, and simulation models estimate that hookworm infection is responsible for >4 million disability-adjusted life years lost annually...
December 8, 2016: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/27928891/early-deterioration-of-iron-status-among-a-cohort-of-bolivian-infants
#7
Rachel M Burke, Paulina A Rebolledo, Anna M Fabiszewski de Aceituno, Rita Revollo, Volga Iñiguez, Mitchel Klein, Carolyn Drews-Botsch, Juan S Leon, Parminder S Suchdev
Iron deficiency (ID) and iron deficiency anemia (IDA) are major contributors to infant and maternal morbidity worldwide. There is limited longitudinal data on iron status in young infants and on methods to adjust iron biomarkers for inflammation. We aimed to quantify the prevalence of inflammation-adjusted ID, anemia, and IDA over the first year in a cohort of Bolivian infants and their mothers. Healthy mother-infant dyads were recruited from two peri-urban hospitals. Infants provided three blood draws (2, 6-8, and 12-18 months; N = 160); mothers provided two blood draws (1 and 6-8 months postpartum [plus third anemia measurement at 12-18 months]; N = 250)...
December 7, 2016: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/27928530/prevalence-of-thalassemia-trait-iron-deficiency-anemia-during-infancy-in-2011-2013-in-a-thalassemia-prevalent-region-north-cyprus
#8
Burçin Şanlidağ, Buse Çağin, Övgü Özenli, Özlem Şahaloğlu, Ceyhun Dalkan, Nilüfer Galip, Arzu Babayiğit Hocaoğlu, Nerin Bahçeciler
BACKGROUND: Iron Deficiency Anemia (IDA) is an important health problem all around the world especially in developing countries. In the Mediterranean countries another prevelant reason of anemia is Thalassemia. Certain strategies had been established as a government policy to reduce prevalence in North Cyprus, such as pre-marital screening of Thalassemia. The prevalence of thalassemia trait has not been evaluated since then. The aim of this study was to detect the prevalence of IDA, thalassemia trait in infants under regular follow-up and to evaluate the compliance to prophylactic iron supplementation (PIS) and its effect on IDA...
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27927768/iron-heme-bach1-axis-is-involved-in-erythroblast-adaptation-to-iron-deficiency
#9
Masahiro Kobayashi, Hiroki Kato, Hiroshi Hada, Ari Itoh-Nakadai, Tohru Fujiwara, Akihiko Muto, Yukihiro Inoguchi, Kenji Ichiyanagi, Wataru Houjou, Naohisa Tomosugi, Hiroyuki Sasaki, Hideo Harigae, Kazuhiko Igarashi
Iron plays the central role in the oxygen transport by the erythrocyte as a constituent of heme and hemoglobin. The importance of iron and heme also resides in their regulatory roles during erythroblast maturation. The transcription factor Bach1 may be involved in their regulatory roles since it is inactivated by direct binding of heme. To address whether Bach1 is involved in the responses of erythroblasts to iron status, low iron conditions that induced severe iron deficiency in mice were established. Under iron deficiency, extensive gene expression changes and mitophagy disorder were induced during maturation of erythroblasts...
December 7, 2016: Haematologica
https://www.readbyqxmd.com/read/27926557/long-term-quality-of-life-of-patients-with-permanent-end-ileostomy-results-of-a-nationwide-cross-sectional-survey
#10
Tobias S Schiergens, Verena Hoffmann, Tamara N Schobel, Gerhard H Englert, Martin E Kreis, Wolfgang E Thasler, Jens Werner, Michael S Kasparek
BACKGROUND: Patients with permanent end ileostomy are at high risk for detrimental stomal effects on their quality of life. However, little is known about the long-term quality of life of these patients. OBJECTIVE: The purpose of this study was to assess long-term quality of life in patients with permanent end ileostomy. DATA SOURCES: Registration at the German self-help organization ILCO was used for this study. STUDY SELECTION: Selection included a cross-sectional survey of 1434 patients with permanent end ileostomy...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27923057/the-effect-of-iron-fortification-on-iron-fe-status-and-inflammation-a-randomized-controlled-trial
#11
Jingqiu Ma, Qianqian Sun, Jinrong Liu, Yanqi Hu, Shanshan Liu, Jie Zhang, Xiaoyang Sheng, K Michael Hambidge
BACKGROUND: Iron deficiency (ID) is common in toddlers in developing countries. Iron fortified or meat-based complementary foods may be effective to prevent ID. OBJECTIVE: Our objective was to compare iron status at 18 months and growth from 6 to 18 months in rural poor toddlers fed 3 different complementary foods. METHODS: The study was nested within a larger trial in which 6-month-old infants were randomized to receive 50g/d meat (MG), an equi-caloric fortified cereal supplement (FG) or local cereal supplement (LG) for 1 year...
2016: PloS One
https://www.readbyqxmd.com/read/27922517/a-5-year-follow-up-of-study-patients-with-asymptomatic-iron-deficiency-anemia-using-a-nurse-led-pathway
#12
Sarah Ann Townsend, Danny Cheung, Elaine Horne, Rupert Ransford
A protocol-driven, systematic pathway was developed to allow rapid and coordinated investigation of patients with iron-deficiency anemia (IDA) in a nurse-delivered outpatient setting. The study objective was to assess the safety and efficacy of the pathway by 5-year outcome data for the exclusion of gastrointestinal (GI) malignancy. This is a 5-year follow-up study of 122 patients entered onto the pathway with negative initial upper and lower GI investigations. The study was conducted at Hereford County Hospital NHS Trust (a district general hospital serving 220,00 people)...
November 2016: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/27918629/new-routes-for-plant-iron-mining
#13
REVIEW
Catherine Curie, Stéphane Mari
I. II. III. IV. References SUMMARY: Plant iron (Fe) uptake relies to a large extent on the capacity of cells to control and extract Fe pools safely conserved in extracytoplasmic environments such as the apoplast and vacuoles, at least as much as on the transport machinery nested in plasma membranes. Recent studies on root and embryo Fe nutrition support this assertion and show that the root Fe-deficiency response also includes the dynamic use of a large Fe reservoir bound to cell wall components in the root apoplast, secretion in the apoplast of phenolic compounds of the coumarin family, which solubilize Fe in calcareous soils, and inhibition of suberization of endodermal cells in order to allow apoplastic and transcellular radial transport of Fe...
December 5, 2016: New Phytologist
https://www.readbyqxmd.com/read/27918586/impact-of-preconception-micronutrient-supplementation-on-anemia-and-iron-status-during-pregnancy-and-postpartum-a-randomized-controlled-trial-in-rural-vietnam
#14
Phuong H Nguyen, Melissa Young, Ines Gonzalez-Casanova, Hoa Q Pham, Hieu Nguyen, Truong V Truong, Son V Nguyen, Kimberly B Harding, Gregory A Reinhart, Reynaldo Martorell, Usha Ramakrishnan
OBJECTIVE: Preconception micronutrient interventions may be a promising approach to reduce anemia and iron deficiency during pregnancy, but currently we have limited data to inform policies. We evaluated whether providing additional pre-pregnancy weekly iron-folic acid (IFA) or multiple micronutrient (MM) supplements compared to only folic acid (FA) improves iron status and anemia during pregnancy and early postpartum. METHODS: We conducted a double blind randomized controlled trial in which 5011 Vietnamese women were provided with weekly supplements containing either only 2800 μg FA (control group), IFA (60 mg Fe and 2800 μg FA) or MM (15 micronutrients with similar amounts of IFA)...
2016: PloS One
https://www.readbyqxmd.com/read/27918350/a-case-of-idiopathic-pulmonary-hemosiderosis-presenting-with-signs-and-symptoms-mimicking-hemolytic-anemia
#15
Dilek Doğruel, Ayşe Erbay, Nalan Yazici, Alev Arslan, Bermal Hasbay Biçen
Idiopathic pulmonary hemosiderosis is primarily a disorder of childhood, which is characterized by hemoptysis, iron deficiency anemia, and diffuse parenchymal infiltrates on chest x-ray secondary to recurrent attacks of alveolar hemorrhage. It can be diagnosed by showing hemosiderin laden macrophages in bronchoalveolar lavage fluid after other specific causes of diffuse alveolar hemorrhage are definitely excluded. A 5-year-old male patient was admitted to our clinic with sudden-onset pallor during iron therapy given for anemia...
December 1, 2016: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27918138/association-of-essential-trace-metals-in-maternal-hair-with-the-risk-of-neural-tube-defects-in-offspring
#16
Lailai Yan, Bin Wang, Zhenjiang Li, Yaqiong Liu, Wenhua Huo, Jingyu Wang, Zhiwen Li, Aiguo Ren
BACKGROUND: The relationship between essential trace metals (ETMs) and the risk of neural tube defects (NTDs) is still unclear. One of the challenges is to evaluate the intake of ETMs of women during their early period of pregnancy. We proposed the hypothesis that an ETM deficiency in women during their early period of pregnancy is associated with an elevated risk of NTDs in offspring. METHODS: We recruited 191 women with NTD-affected pregnancies (case group) and 261 women who delivered healthy infants (control group)...
December 5, 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27917693/identification-of-kcnq1-compound-heterozygous-mutations-in-three-chinese-families-with-jervell-and-lange-nielsen-syndrome
#17
Cuicui Wang, Yu Lu, Jing Cheng, Lei Zhang, Wei Liu, Weihua Peng, Di Zhang, Hong Duan, Dongyi Han, Huijun Yuan
CONCLUSION: Besides expanding the spectrum of KCNQ1 mutations causing Jervell and Lange-Nielsen Syndrome (JLNS), the results showed diversity of its phenotypes, and emphasized the importance of molecular genetic analysis in confirming clinical diagnosis and making diagnosis possible before the emergency symptoms for deaf individuals. OBJECTIVES: This study aimed to investigate four patients from three Chinese families with congenital hearing loss clinically and genetically...
December 5, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27917348/resolution-of-constipation-anal-stricture-and-iron-deficiency-anemia-after-iron-infusion-an-analogy-with-plummer-vinson-syndrome
#18
Vijaypal Arya, Shikha Singh, Shashank Agarwal, Arjun Ohri
BACKGROUND: Anal stricture is a disabling condition which is often unresponsive to conservative medical management. The complications of surgical procedures such as dilatations and anoplasty make it a formidable treatment challenge. Through this case, we report and explore a new medical treatment for ano-rectal strictures with an analogy to Plummer Vinson syndrome. A 69-year-old male presented with chronic constipation, rectal pain, and easy fatigability. The physical exam was negative for anal fissure and a digital rectal examination could not be completed because an index finger could not be advanced through the narrowed anus...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917226/iron-deficiency-anaemia-among-apparently-healthy-pre-school-children-in-lagos-nigeria
#19
Anirban Mandal, Puneet Kaur Sahi
No abstract text is available yet for this article.
September 2016: African Health Sciences
https://www.readbyqxmd.com/read/27916873/the-effect-of-low-dose-iron-and-zinc-intake-on-child-micronutrient-status-and-development-during-the-first-1000-days-of-life-a-systematic-review-and-meta-analysis
#20
REVIEW
Nicolai Petry, Ibironke Olofin, Erick Boy, Moira Donahue Angel, Fabian Rohner
Adequate supply of micronutrients during the first 1000 days is essential for normal development and healthy life. We aimed to investigate if interventions administering dietary doses up to the recommended nutrient intake (RNI) of iron and zinc within the window from conception to age 2 years have the potential to influence nutritional status and development of children. To address this objective, a systematic review and meta-analysis of randomized and quasi-randomized fortification, biofortification, and supplementation trials in women (pregnant and lactating) and children (6-23 months) delivering iron or zinc in doses up to the recommended nutrient intake (RNI) levels was conducted...
November 30, 2016: Nutrients
keyword
keyword
66545
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"