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https://www.readbyqxmd.com/read/27908570/sleep-related-disorders-in-latin-american-children-with-atopic-dermatitis-a-case-control-study
#1
M Urrutia-Pereira, D Solé, N A Rosario, H J C Neto, V Acosta, C F Almendarez, M M Avalos, H Badellino, F Berroa, M Álvarez-Castelló, A J Castillo, R L Castro-Almarales, M M De la Cruz, A M Cepeda, C Fernandez, M González-León, J Lozano-Saenz, C Sanchez-Silot, J C Sisul-Alvariza, M Valentin-Rostan, R O S Sarni
BACKGROUND: Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4-10 years) from nine countries, and in normal controls (C). METHODS: Parents from 454 C and 340 AD children from referral clinics answered the Children Sleep Habits Questionnaire (CSHQ), a one-week retrospective 33 questions survey under seven items (bedtime resistance, sleep duration, sleep anxiety, night awakening, parasomnias, sleep-disordered breathing and daytime sleepiness)...
November 28, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27783807/cerebral-vasomotor-reactivity-assessment-using-transcranial-doppler-and-mri-with-apnea-test
#2
C R Campos Herrera, G C Beltramini, W M Avelar, F O Lima, L M Li
Differently from previous studies that used Transcranial Doppler (TCD) and functional MRI (fMRI) for cerebral vasomotor reactivity (CVR) assessment in patients with carotid stenosis (CS), we assessed CVR using an identical stimulus, the Breath-Holding Test (BHT). We included 15 patients with CS and 7 age-matched controls to verify whether fMRI responded differently to BHT between groups and to calculate the agreement rate between tests. For TCD, impaired CVR was defined when the mean percentage increase on middle cerebral artery velocities was ≤31% on 3 consecutive 30-s apnea intercalated by 4-min normal breathing intervals...
October 24, 2016: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/27740900/asthma-and-subjective-sleep-disordered-breathing-in-a-large-cohort-of-urban-adolescents
#3
Stephanie O Zandieh, Amarilis Cespedes, Adam Ciarleglio, Wallace Bourgeois, David M Rapoport, Jean-Marie Bruzzese
OBJECTIVE: Sleep disordered breathing (SDB) has not been well studied in urban adolescents with asthma in community settings. Nor has the association of SDB symptoms and asthma severity been studied. We characterized self-reported symptoms suggesting SDB and investigated the association of SDB symptoms, probable asthma, and asthma severity. METHODS: 9,565 adolescents from 21 inner-city high schools were screened for an asthma intervention study. Students reported on symptoms suggesting SDB using questions from the 2007 NHANES, if they were ever diagnosed with asthma, and on asthma symptoms...
October 14, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27633813/three-different-turbinoplasty-techniques-combined-with-septoplasty-prospective-randomized-trial
#4
Johannes A Veit, Melanie Nordmann, Britta Dietz, Fabian Sommer, Jörg Lindemann, Nicole Rotter, Jens Greve, Achim von Bomhard, Thomas K Hoffmann, Ricarda Riepl, Marc O Scheithauer
OBJECTIVES/HYPOTHESIS: Septal deviation and hypertrophic inferior turbinates are a frequent cause of nasal breathing disorders. The goal of this study was to prove the effectiveness and safety of three current turbinoplasty techniques. STUDY DESIGN: This is a prospective, three-arm, single-blinded, single-center, randomized controlled trial. METHODS: Sixty patients were randomly assigned to either anterior turbinoplasty (ATP) (n = 20), radiofrequency ablation (RFA) (n = 19; Celon Pro Breath), or novel submucous radial diode laser ablation (DLA) (n = 21; ELVeS Radial PainLess, wavelength = 1,470 nm), each in combination with standard septoplasty...
September 16, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27594405/sleep-disorders-in-latin-american-children-with-asthma-and-or-allergic-rhinitis-and-normal-controls
#5
M Urrutia-Pereira, D Solé, H J Chong Neto, V Acosta, A M Cepeda, M Álvarez-Castelló, C F Almendarez, J Lozano-Saenz, J C Sisul-Alvariza, N A Rosario, A J Castillo, M Valentin-Rostan, H Badellino, R L Castro-Almarales, M González-León, C Sanchez-Silot, M M Avalos, C Fernandez, F Berroa, M M De la Cruz, R O S Sarni
BACKGROUND: Asthma and/or allergic rhinitis have been associated with sleep disorders. The aim of this study was to evaluate sleep disorders in Latin-American children (4-10 years) from nine countries, with persistent asthma (A) and/or allergic rhinitis (AR) and in normal controls (C). METHODS: Parents from 454 C children and 700 A and/or AR children followed up in allergy reference clinics completed the Children's Sleep Habits Questionnaire (CSHQ) which is a retrospective one-week questionnaire composed of 33 questions composed of seven subscales (bedtime resistance, sleep duration, sleep anxiety, night wakings, parasomnias, sleep-disordered breathing and daytime sleepiness)...
September 1, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27538513/yogic-breathing-when-compared-to-attention-control-reduces-the-levels-of-pro-inflammatory-biomarkers-in-saliva-a-pilot-randomized-controlled-trial
#6
Waleed O Twal, Amy E Wahlquist, Sundaravadivel Balasubramanian
BACKGROUND: Self-report measures indicate that Yoga practices are perceived to reduce stress; however, molecular mechanisms through which YB affects stress are just beginning to be understood. While invasive sampling such as blood has been widely used to measure biological indicators such as pro-inflammatory biomarkers, the use of saliva to measure changes in various biomolecules has been increasingly recognized. As Yoga practice stimulates salivary secretion, and saliva is considered a source of biomarkers, changes in salivary cytokines before and after Yogic breathing exercise as specified in an ancient Tamil script, Thirumanthiram, were examined using a Cytokine Multiplex to compare to Attention Control (AC) group...
2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27508712/-op-4c-07-loaded-slow-breathing-training-reduces-home-resting-blood-pressure-in-older-patients-with-isolated-systolic-hyopertension
#7
C Jones, B Sangthong, O Pachirat, D Jones
OBJECTIVE: To determine whether slow loaded breathing training can enhances blood pressure reduction associated with conventional medication. DESIGN AND METHOD: Randomised controlled trialThirty patients (66 ± 4 years) with isolated systolic hypertension and managed with conventional medication, were randomized into loaded breathing (LB: 6 breaths/min, 18 cm H2O), unloaded breathing (ULB: 6 breaths/min, no load) or control (C: normal breathing) groups...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27507597/label-free-optical-detection-of-age-related-and-diabetic-oxidative-damage-in-human-aqueous-humors
#8
Sang Woong Moon, Wansun Kim, Samjin Choi, Jae-Ho Shin
In this study, we investigate the biochemical characteristics of oxidative stress in age-related macular degeneration (AMD) and diabetic retinopathy (DR) by analyzing aqueous humors. Nondiabetic cataract aqueous humor was used as the control. The level of oxidative damage was evaluated based on changes in Raman spectral intensity. Seven prominent peaks were detected at 1002, 1043, 1062, 1352, 1419, 1454, and 1656 cm(-1) . We proposed four multimodal biomarkers to distinguish these peaks based on the ratios of Raman intensities in two wavelengths, including CHO (C-O stretching or C-O-H bending modes), AG (adenine and guanine), PRO-AG (protein and AG), and PHEα (phenylalanine symmetric ring breath and amide I α-helix) markers...
August 10, 2016: Microscopy Research and Technique
https://www.readbyqxmd.com/read/27492518/clinical-characteristics-of-adult-asthma-associated-with-small-airway-dysfunction
#9
S Kjellberg, B K Houltz, O Zetterström, P D Robinson, Per M Gustafsson
Suboptimal asthma control is common despite modern asthma therapy. The degree of peripheral airway involvement remains unclear and poor medication delivery to these regions might be a contributing reason for this failure in obtaining adequate symptom control. A cohort of 196 adults (median (range) age 44 (18-61) years, 109 females, 54 ex-smokers, six current smokers) with physician-diagnosed asthma were recruited from primary care. Subjects were characterized clinically by interviews, questionnaires, skin prick tests (SPT) and blood eosinophil counts...
August 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27476581/the-effect-of-camicinal-gsk962040-a-motilin-agonist-on-gastric-emptying-and-glucose-absorption-in-feed-intolerant-critically-ill-patients-a-randomized-blinded-placebo-controlled-clinical-trial
#10
Marianne J Chapman, Adam M Deane, Stephanie L O'Connor, Nam Q Nguyen, Robert J L Fraser, Duncan B Richards, Kimberley E Hacquoil, Lakshmi S Vasist Johnson, Matthew E Barton, George E Dukes
BACKGROUND: The promotility agents currently available to treat gastroparesis and feed intolerance in the critically ill are limited by adverse effects. The aim of this study was to assess the pharmacodynamic effects and pharmacokinetics of single doses of the novel gastric promotility agent motilin agonist camicinal (GSK962040) in critically ill feed-intolerant patients. METHODS: A prospective, randomized, double-blind, parallel-group, placebo-controlled, study was performed in mechanically ventilated feed-intolerant patients [median age 55 (19-84), 73 % male, APACHE II score 18 (5-37) with a gastric residual volume ≥200 mL]...
2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27412486/which-airway-pressure-should-be-applied-during-breath-hold-in-dogs-undergoing-thoracic-computed-tomography
#11
Alessandro Guarracino, Luca Lacitignola, Edoardo Auriemma, Valentina De Monte, Salvatore Grasso, Antonio Crovace, Francesco Staffieri
This randomized controlled trial study aimed to identify the optimal positive pressure (PP) level that can clear atelectasis while avoiding pulmonary hyperinflation during the breath-hold technique in dogs undergoing thoracic computed tomography (CT). Sixty dogs affected by mammary tumors undergoing thoracic CT for the screening of pulmonary metastases were randomly assigned to six groups with different levels of PP during the breath-hold technique: 0 (control), 5 (PP5), 8 (PP8), 10 (PP10), 12 (PP12), and 15 (PP15) cmH2 O...
September 2016: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/27399326/free-breathing-sparse-sampling-cine-mr-imaging-with-iterative-reconstruction-for-the-assessment-of-left-ventricular-function-and-mass-at-3-0-t
#12
Sonja Sudarski, Thomas Henzler, Holger Haubenreisser, Christina Dösch, Michael O Zenge, Michaela Schmidt, Mariappan S Nadar, Martin Borggrefe, Stefan O Schoenberg, Theano Papavassiliu
Purpose To prospectively evaluate the accuracy of left ventricle (LV) analysis with a two-dimensional real-time cine true fast imaging with steady-state precession (trueFISP) magnetic resonance (MR) imaging sequence featuring sparse data sampling with iterative reconstruction (SSIR) performed with and without breath-hold (BH) commands at 3.0 T. Materials and Methods Ten control subjects (mean age, 35 years; range, 25-56 years) and 60 patients scheduled to undergo a routine cardiac examination that included LV analysis (mean age, 58 years; range, 20-86 years) underwent a fully sampled segmented multiple BH cine sequence (standard of reference) and a prototype undersampled SSIR sequence performed during a single BH and during free breathing (non-BH imaging)...
July 11, 2016: Radiology
https://www.readbyqxmd.com/read/27387180/prone-position-in-thoracoscopic-esophagectomy-improves-postoperative-oxygenation-and-reduces-pulmonary-complications
#13
Dai Otsubo, Tetsu Nakamura, Masashi Yamamoto, Shingo Kanaji, Kiyonori Kanemitsu, Kimihiro Yamashita, Tatsuya Imanishi, Taro Oshikiri, Yasuo Sumi, Satoshi Suzuki, Daisuke Kuroda, Yoshihiro Kakeji
BACKGROUND: While thoracoscopic esophagectomy is a widely performed surgical procedure, only few studies regarding the influence of body position on changes in circulation and breathing, after the surgery, have been reported. This study aimed at evaluating the effect of body position, during surgery, on the postoperative breathing functions of the chest. METHODS: A total of 266 patients who underwent right-sided transthoracic esophagectomy for esophageal cancer from 2004 to 2012 were included in this study...
July 7, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27382934/the-efficacy-of-intravenous-hyoscine-n-butylbromide-during-colonoscopy-a-prospective-randomized-double-blind-placebo-controlled-study
#14
RANDOMIZED CONTROLLED TRIAL
B Dinc, U R Gunduz, B Bas, N Ay, U Koc, O Z Oner, I Gomceli
BACKGROUND: Colonic spasm makes colonoscope advancement difficult. This prospective, randomized, double-blind, placebo-controlled study aimed to evaluate the efficacy of hyoscine-N-butylbromide as an antispasmodic during colonoscopy. METHOD: Patients referred for elective colonoscopy were randomized into the study and placebo groups. Before the procedure, the study and placebo groups received 20 mg intra-venous hyoscine-N-butylbromide and intravenous saline solution of the same amount, respectively...
April 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/27367724/beneficial-effect-of-synbiotic-supplementation-on-hepatic-steatosis-and-anthropometric-parameters-but-not-on-gut-permeability-in-a-population-with-nonalcoholic-steatohepatitis
#15
Silvia M Ferolla, Cláudia A Couto, Luciana Costa-Silva, Geyza N A Armiliato, Cristiano A S Pereira, Flaviano S Martins, Maria de Lourdes A Ferrari, Eduardo G Vilela, Henrique O G Torres, Aloísio S Cunha, Teresa C A Ferrari
Nonalcoholic fatty liver disease is the most prevalent chronic liver disease in Western countries; it can progress to nonalcoholic steatohepatitis (NASH), cirrhosis and hepatocarcinoma. The importance of gut-liver-adipose tissue axis has become evident and treatments targeting gut microbiota may improve inflammatory and metabolic parameters in NASH patients. In a randomized, controlled clinical trial, involving 50 biopsy-proven NASH patients, we investigated the effects of synbiotic supplementation on metabolic parameters, hepatic steatosis, intestinal permeability, small intestinal bacterial overgrowth (SIBO) and lipopolysaccharide (LPS) serum levels...
2016: Nutrients
https://www.readbyqxmd.com/read/27364144/assessment-of-autonomic-function-in-a-cohort-of-patients-with-anca-associated-vasculitis
#16
P Moog, O Eren, M Witt, V Rauschel, S Kossegg, A Straube, M Grünke, H Schulze-Koops
OBJECTIVE: To assess symptoms and objective parameters of autonomic dysfunction (AD) in patients with ANCA-associated vasculitides. METHODS: Symptoms and objective parameters of AD were assessed in patients with ANCA-associated vasculitis and in age-matched healthy controls. Autonomic symptoms were explored by COMPASS31, a validated questionnaire addressing symptoms of six autonomic domains (orthostatic, vasomotor, secretomotor, gastrointestinal, pupillomotor, and bladder dysfunction)...
August 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27351245/adjunctive-therapy-with-curcumin-for-peptic-ulcer-a-randomized-controlled-trial
#17
A Khonche, O Biglarian, Y Panahi, G Valizadegan, S S Soflaei, M E Ghamarchehreh, M Majeed, A Sahebkar
BACKGROUND: Curcumin, the bioactive ingredient of turmeric, has been shown to improve the treatment of peptic ulcer (PU) in animal studies. However, clinical studies confirming this effect of curcumin have been scant. OBJECTIVE: To assess the efficacy of adjunctive therapy with curcumin on the eradication of Helicobacter pylori infection and severity of dyspepsia in patients with PU. METHODS: In this randomized double-blind placebo-controlled parallel-group trial, patients diagnosed with PU were assigned to standard H...
August 2016: Drug Research
https://www.readbyqxmd.com/read/27339114/two-conformational-states-in-d-shaped-dna-effects-of-local-denaturation
#18
O-Chul Lee, Cheolhee Kim, Jae-Yeol Kim, Nam Ki Lee, Wokyung Sung
The bending of double-stranded(ds) DNA on the nano-meter scale plays a key role in many cellular processes such as nucleosome packing, transcription-control, and viral-genome packing. In our recent study, a nanometer-sized dsDNA bent into a D shape was formed by hybridizing a circular single-stranded(ss) DNA and a complementary linear ssDNA. Our fluorescence resonance energy transfer (FRET) measurement of D-DNA revealed two types of conformational states: a less-bent state and a kinked state, which can transform into each other...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27316368/observational-pilot-study-of-reported-symptoms-of-obstructive-sleep-apnoea-in-children-with-epilepsy
#19
Don S Urquhart, Olaniyi O Kehinde, Ailsa E Mclellan
AIM: To estimate symptoms of obstructive sleep apnoea (OSA) and excessive daytime sleepiness (EDS) in children with epilepsy (CWE) compared with those in a typically developing comparison group. CWE are known to have poor sleep, with increased rates of OSA suggested. METHOD: The Sleep-Related Breathing Disorder scale of the Pediatric Sleep Questionnaire (PSQ-SRBD) was used to estimate OSA symptoms, with scores ≤0.33 known to be highly sensitive and specific for OSA...
October 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27251105/controlled-mechanical-ventilation-with-constant-positive-end-expiratory-pressure-and-alveolar-recruitment-manoeuvres-during-anaesthesia-in-laterally-or-dorsally-recumbent-horses
#20
Klaus Hopster, Karl Rohn, Bernhard Ohnesorge, Sabine Br Kästner
OBJECTIVE: To compare the effects of controlled mechanical ventilation (CMV) and constant positive end-expiratory pressure (PEEP) and interposed recruitment manoeuvres (RMs) with those of CMV without PEEP on gas exchange during general anaesthesia and the early recovery period. STUDY DESIGN: Prospective, randomized clinical trial. ANIMALS: A total of 48 Warmblood horses undergoing elective surgery in lateral (Lat) (n = 24) or dorsal (Dors) (n = 24) recumbency...
June 2, 2016: Veterinary Anaesthesia and Analgesia
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