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central lymph node thyroid carcinoma

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https://www.readbyqxmd.com/read/28635213/-risk-factors-for-central-neck-lymph-node-metastases-of-papillary-thyroid-carcinoma
#1
Y S Sun, H J Lyu, Y R Zhao, S S Zhang, Y X Bai, B Y Shi
Objective: To investigate the impact factors for central neck lymph node metastases(CLNM) of papillary thyroid carcinoma(PTC). Methods: A total of 498 patients with PTC who underwent total or hemi-thyroidectomy plus central neck lymph node dissection between January 2014 and July 2016 were included. Univariate and multivariate analyses were performed to identify clinicopathological characteristics, thyroid function parameters and US findings that associated with CLNM of PTC. A nomogram was developed to predict the probability of CLNM...
June 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28635212/-clinical-features-of-postoperative-cervical-lymph-nodes-recurrence-in-papillary-thyroid-carcinoma
#2
Y Y He, B Zhang, Y B Zhang, Z G Xu, P Z Tang
Objective: To analyse the postoperative metastasis or recurrence of cervical lymph nodes in individual neck levels for papillary thyroid carcinoma and to evaluate the outcomes and complications of re-surgery. Methods: A retrospective cohort study of 259 patients who underwent lymph node dissection for PTC relapse from January 2010 to June 2011. Lymph node metastases in each of neck levels were detected, postoperative complications were evaluated, and the patients were followed up with examining thyroglobulin levels to assess the therapeutic effect...
June 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28624039/the-total-number-of-prelaryngeal-and-pretracheal-lymph-node-metastases-is-it-a-reliable-predictor-of-contralateral-central-lymph-node-metastasis-in-papillary-thyroid-carcinoma
#3
Qiang Chen, Tao Wei, Xun-Li Wang, Zhi-Hui Li, Zhen-Hong Du, Jing-Qiang Zhu
BACKGROUND: Central lymph node (CLN) metastasis in papillary thyroid carcinoma (PTC) is common and being able to predict CLN metastasis helps surgeons determine individualized therapy. However, the relationship between contralateral CLN metastasis and the total number of positive lymph nodes (LNs) in the combined prelaryngeal and pretracheal region remains unclear. This study aimed to investigate whether the total number of positive LNs in the combined prelaryngeal and pretracheal region has clinical significance as a predictor for contralateral CLN metastasis...
June 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28614242/lymph-node-metastasis-characteristics-of-papillary-thyroid-carcinoma-located-in-the-isthmus-a-single-center-analysis
#4
Genpeng Li, Jianyong Lei, Qian Peng, Ke Jiang, Wenjie Chen, Wanjun Zhao, Zhihui Li, Rixiang Gong, Tao Wei, Jingqiang Zhu
The frequency and pattern of lymph node metastasis and the extent of dissection for isthmic papillary thyroid carcinoma (PTC) remain unclear, and the aim of this present study was to evaluate these characteristics and to attempt to detect the best surgical protocol for isthmic PTCs. A total of 3185 consecutive patients with PTCs were reviewed. Of these patients, 47 with a single isthmic PTC were enrolled in our study, and matched 47 patients with a single PTC located in the unilateral lobe were randomly selected and added for comparison of their baseline tumor characteristics and lymph node metastasis characteristics...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28612210/surgical-approach-to-level-vi-in-papillary-thyroid-carcinoma-an-overview
#5
REVIEW
Carmela De Crea, Marco Raffaelli, Luca Sessa, Celestino Pio Lombardi, Rocco Bellantone
One of the most controversial issues in the treatment of thyroid cancer is the management of the central neck nodes in patients with papillary thyroid carcinoma (PTC). Lymph node involvement is common in patients with PTC and it may negatively affect recurrence rate and, probably, survival. Although therapeutic compartment-oriented central neck dissection is the standard treatment for patients with clinical nodal involvement (cN1) PTC, the role and the extension for elective or prophylactic central neck dissection (PCND) in patients with clinically node negative (cN0) neoplasms remains controversial...
June 13, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28599790/long-term-outcomes-of-central-neck-dissection-for-cn0-papillary-thyroid-carcinoma
#6
Davide Giordano, Andrea Frasoldati, Enrico Gabrielli, Carmine Pernice, Michele Zini, Andrea Castellucci, Simonetta Piana, Alessia Ciarrocchi, Silvio Cavuto, Verter Barbieri
OBJECTIVE: The risk-benefit ratio of central neck dissection (CND) in patients affected by papillary thyroid carcinoma (PTC) without clinical or ultrasonographic (US) evidence of neck lymph node metastasis (cN0) is currently debated. The aim of this study was to evaluate long-term outcome of CND on locoregional recurrence, distant metastasis, survival, and postoperative complications in a large series of patients with cN0-PTC. STUDY DESIGN: Observational retrospective controlled study...
June 7, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28591551/papillary-thyroid-carcinoma-analysis-of-the-central-compartment-s-lymph-nodes-metastases
#7
Ján Sojak, Marian Sičák, Adrian Kališ, Michal Slašťan
BACKGROUND: Papillary thyroid carcinoma is typical by regional lymph nodes metastases. Therefore we decided to analyse associated risk factors. OBJECTIVE: In this retrospective study we focused on the incidence of metastatic involvement of the central compartment's lymph nodes correlated with age, size of the primary tumour, infiltration of thyroid gland capsule, positive lymphangioinvasion in order to assess risk factors. METHOD: We analysed group of 156 patients with papillary carcinoma, who have undergone total thyroidectomy and bilateral elective central compartment neck dissection...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/28545107/predictive-factors-of-right-paraesophageal-lymph-node-metastasis-in-papillary-thyroid-carcinoma-single-center-experience-and-meta-analysis
#8
Young Min Park, Sang Min Lee, Dong Won Kim, Sung-Chan Shin, Byung-Joo Lee
BACKGROUND: We performed this retrospective study to identify predictors of right paraesophageal lymph node metastasis, and reviewed previous studies related to this topic. METHODS: Between June 2005 and March 2015, 1107 patients were diagnosed with papillary thyroid carcinoma and underwent surgery at Pusan National University Hospital. RESULTS: Right paraesophageal lymph node metastasis was observed in 171 (15.4%) patients. Multivariate analyses showed that the risk of right paraesophageal metastasis was significantly associated with tumor size, location, a higher number of metastatic central lymph nodes, and lateral lymph node metastasis...
2017: PloS One
https://www.readbyqxmd.com/read/28530323/-papillary-thyroid-carcinoma-treatment-is-the-pendulum-shifting
#9
REVIEW
Sagit Stern, Elad Dagan, Eran E Alon, Ziv Gil, Gideon Bachar
The incidence of papillary thyroid carcinoma has been on the rise in the past few decades while the disease specific mortality remains stable. During prophylactic central neck dissection (level 6), an average of 60% positive occult lymph nodes metastasis are found, hence the justification for performing a prophylactic central neck dissection. The opponents for performing neck dissection claim that the disease specific mortality is low regardless of the operation and that adding a neck dissection will, significantly, increase surgical morbidity...
August 2016: Harefuah
https://www.readbyqxmd.com/read/28513128/clinical-features-of-recently-diagnosed-papillary-thyroid-carcinoma-in-elderly-patients-aged-65-and-older-based-on-10-years-of-sonographic-experience-at-a-single-institution-in-korea
#10
Eun Sil Kim, Younghen Lee, Hyungsuk Seo, Gil Soo Son, Soon Young Kwon, Young-Sik Kim, Ji-A Seo, Nan Hee Kim, Sang-Il Suh, Inseon Ryoo, Sung-Hye You
Purpose: The aim of this study was to assess the characteristics of papillary thyroid carcinoma (PTC) in patients aged 65 and older in order to predict postoperative recurrence based on the results of ultrasonographic surveillance. Methods: Among 1,494 patients (200 male and 1,294 female; mean age, 46.6±11.3 years) who underwent surgery for thyroid cancer at our institution between 2006 and 2015, we retrospectively enrolled 150 PTC patients (29 male and 121 female; mean age, 69...
April 13, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28506418/timing-and-extension-of-lymphadenectomy-in-medullary-thyroid-carcinoma-a-case-series-from-a-single-institution
#11
Andrea Polistena, Alessandro Sanguinetti, Roberta Lucchini, Sergio Galasse, Massimo Monacelli, Stefano Avenia, Andrea Boccolini, Louis Banka Johnson, Nicola Avenia
BACKGROUND: Medullary thyroid carcinoma is an aggressive tumor and presents with significant morbidity and mortality and a high rate of lymph node metastases. The combination of total thyroidectomy and cervical lymphadenectomy is the essential treatment for those patients presenting with cervical lymph node metastases. MATERIALS AND METHODS: A retrospective analysis of 117 patients operated for medullary thyroid carcinoma over a period of 15 years at a single institution...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28506412/rationality-in-prophylactic-central-neck-dissection-in-clinically-node-negative-cn0-papillary-thyroid-carcinoma-is-there-anything-more-to-say-a-decade-experience-in-a-single-center
#12
C Dobrinja, M Troian, T Cipolat Mis, G Rebez, S Bernardi, B Fabris, L Piscopello, P Makovac, F Di Gregorio, N de Manzini
AIM: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. Despite its extremely favorable prognosis, cervical lymph node metastases are a common feature of PTC and a known independent risk factor for local recurrence. However, the role of prophylactic central neck dissection (PCND) remains a matter of debate in patients with clinically node-negative (cN0) PTC. To better clarify the current role of PCND in the surgical treatment of PTC, evaluating advantages and disadvantages of PCND and outcome of cN0 PTC patients who have been treated with either total thyroidectomy alone or in combination with PCND...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28502882/single-incision-endoscopic-thyroidectomy-for-papillary-thyroid-cancer-a-pilot-study
#13
Jinbeom Cho, Yohan Park, Jongmin Baek, Kiyoung Sung
BACKGROUND: Recently, we have reported single incision endoscopic thyroidectomy using an axillary approach with gas inflation (SIET) in cases with benign thyroid tumors to reduce post-operative pain and invasiveness of the conventional endoscopic thyroidectomy. The aim of this study was to present our experiences with SIET for papillary thyroid cancer (PTC). METHODS: Patients who were diagnosed with histologically papillary thyroid carcinoma (≤1 cm) with single, unilateral, and intra-thyroidal lesion and without clinical lymph node metastasis were included...
May 11, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28488911/comparison-between-video-assisted-and-open-lateral-neck-dissection-for-papillary-thyroid-carcinoma-with-lateral-neck-lymph-node-metastasis-a-prospective-randomized-study
#14
Deguang Zhang, Li Gao, Lei Xie, Gaofei He, Jian Chen, Liang Fang, Xiujun Cai
BACKGROUND: The safety and oncologic completeness of video-assisted lateral neck dissection (VALND) for papillary thyroid carcinoma (PTC) with lateral neck lymph node metastasis (LNM) have been reported. However, their generalization has remained limited because the advantages and drawbacks are not well demonstrated. MATERIALS AND METHODS: A total of 64 patients with PTC and unilateral lateral neck LNM who underwent total thyroidectomy with central compartment neck dissection and lateral neck dissection (LND) were prospectively enrolled...
May 10, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28473292/risk-factors-and-the-preoperative-assessment-of-right-para-oesophageal-lymph-node-metastasis-in-right-lobe-papillary-thyroid-carcinoma-a-case-series
#15
You Qu, Hao Zhang, Ping Zhang, Wenwu Dong, Liang He, Wei Sun, Jinhao Liu
BACKGROUND: Right para-oesophageal lymph nodes (RPELN) are included among the right central compartment lymph nodes (rCLN) and located behind right recurrent laryngeal nerve (rRLN). However, due to the likelihood of increasing postoperative complications, and the extremely difficulties of RPELN dissection, the decision to perform RPELN dissection remains controversial. The aim of this study was to explore the risk factors of RPELN metastasis and evaluate RPELN metastasis by preoperative examination...
June 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28454667/optimal-extent-of-prophylactic-central-neck-dissection-for-papillary-thyroid-carcinoma-comparison-of-unilateral-versus-bilateral-central-neck-dissection
#16
Han Seok Yoo, Myung Chul Shin, Yong Bae Ji, Chang Myeon Song, Seung Hwan Lee, Kyung Tae
OBJECTIVE: The aim of the study was to determine the optimal extent of prophylactic central neck dissection (pCND) in papillary thyroid carcinoma (PTC). MATERIALS AND METHODS: We studied 384 patients with clinically node-negative unilateral PTC who had undergone total thyroidectomy with pCND. Of these, 169 patients underwent unilateral pCND, and 215, bilateral pCND. RESULTS: Age, sex, and TNM stage did not differ between the two groups. The rates of occult central lymph node metastasis were 34...
April 25, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28446060/patterns-of-initial-recurrence-in-completely-resected-papillary-thyroid-carcinoma
#17
Hosu Kim, Tae Hyuk Kim, Jun-Ho Choe, Jung-Han Kim, Jee Soo Kim, Young Lyun Oh, Soo Yeon Hahn, Jung Hee Shin, Sang Ah Chi, Sin-Ho Jung, Young Nam Kim, Hye In Kim, Sun Wook Kim, Jae Hoon Chung
BACKGROUND: Despite improvements in the surgical and medical treatment of papillary thyroid carcinoma (PTC), subsets of patients suffer from structural recurrence after initial treatment. This study evaluated the timing and patterns of recurrence in completely resected PTC patients. METHODS: A retrospective review of a prospectively maintained thyroid cancer database was performed. The timing and patterns of recurrence were reviewed in 2250 patients with PTC >1 cm who achieved complete remission after total thyroidectomy and/or radioactive iodine treatment...
May 18, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28441828/-clinical-analysis-of-seven-cases-of-pulmonary-malignant-tumors-in-children
#18
D Xu, Z M Chen, W Z Gu, Y S Wang, M X Huang, L F Tang, Y Y Zhang, Y Jiang
Objective: To understand the clinical manifestation, imaging characteristics and outcomes of pulmonary malignant tumors in children. Method: We retrospectively collected information about seven cases of pulmonary malignant tumors in children in our hospital from Jan 2010 to Dec 2016. The information included clinical manifestation, imaging characteristics, pathologic results, and treatment. Result: (1) All the seven patients firstly visited pediatric internal medicine departments. Symptoms included cough (n=6), dyspnea (n=4), fever (n=2), anorexia (n=2), chest tightness (n=1), chest pain (n=1), lameness (n=1), abdominal distension and constipation (n=1)...
April 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28441802/-central-compartment-reoperation-for-recurrent-persistent-differentiated-thyroid-cancer
#19
Y B Zhang, B Zhang, D G Yan, X W Zhang, Z G Xu, P Z Tang
Objective: To analyze the incidences of complications after central compartment reoperation for recurrent/persistent differentiated thyroid cancer, and to investigate the safety and feasiblity of central compartment reoperation. Methord: A total of 109 patients who underwent central compartment reoperation for recurrent/persistent differentiated thyroid cancer from January 1, 2011 to March 31, 2016 in Cancer Hospital, Chinese Academy of Medical Sciences was analysed retrospectively, and the incidences of reoperation-related complications were evaluated...
April 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28417186/endoscopic-central-lymph-node-dissection-via-breast-combined-with-oral-approach-for-papillary-thyroid-carcinoma-a-preliminary-study
#20
Guo-Yang Wu, Jin-Bo Fu, Fu-Sheng Lin, Ye-Zhe Luo, En-de Lin, Wei Yan
OBJECTIVE: To investigate the feasibility and necessity of endoscopic thyroidectomy with central lymph node dissection via the combined breast and trans-oral approaches. METHODS: Six patients with papillary thyroid carcinoma who underwent endoscopic total thyroidectomy with central node dissection via combined breast and trans-oral approaches from November 2014 to January 2015 in Zhongshan Hospital, Xiamen University, were analyzed. RESULTS: After completion of endoscopic central lymph node dissection via the traditional breast approach, eight pieces of lymph nodes could still be dissected via the trans-oral approach...
April 17, 2017: World Journal of Surgery
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