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central lymph node thyroid carcinoma

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https://www.readbyqxmd.com/read/29439716/risk-factors-of-lateral-lymph-node-metastasis-in-cn0-papillary-thyroid-carcinoma
#1
Daixing Hu, Jing Zhou, Wei He, Jie Peng, Yijia Cao, Haoyu Ren, Yu Mao, Yi Dou, Wei Xiong, Qi Xiao, Xinliang Su
BACKGROUND: Cervical lymph node metastasis of papillary thyroid carcinoma (PTC) is common. However, whether undergoing prophylactic central lymph node (CLN) dissection or lateral lymph node (LLN) dissections to prevent metastasis is still controversial. This study aimed to retrospectively investigate the risk factors of LLN metastasis in clinical lymph node-negative (cN0) PTC patients. METHODS: We retrospectively studied 783 lymph node-negative (cN0) PTC patients who underwent total thyroidectomy plus CLN dissection and LLN dissection...
February 13, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29438531/characteristics-of-follicular-variant-papillary-thyroid-carcinoma-in-a-pediatric-cohort
#2
S L Samuels, L F Surrey, C P Hawkes, M Amberge, S Mostoufi-Moab, J E Langer, N S Adzick, K Kazahaya, T Bhatti, Z Baloch, V A LiVolsi, A J Bauer
Context: In adults, non-invasive follicular variant papillary thyroid carcinoma (FVPTC) is considered low risk for metastasis and persistent/recurrent disease. Objective: The goal of this study was to assess the clinical, sonographic, and histopathological features of FVPTC in a pediatric cohort. Design: A retrospective review of subjects < 19 years of age with papillary thyroid carcinoma (PTC) who underwent thyroidectomy between January 2010 and July 2015...
February 8, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29429179/-evaluation-of-central-lymph-node-dissection-for-papillary-thyroid-carcinoma-in-cn0-t1-t2
#3
S Y Zhao, Y H Ma, Z Yin, X X Zhan, R C Cheng, J Qian
Objective: To evaluate the application of the central lymph node dissection (CLND) for papillary thyroid carcinoma (PTC) in cN0 T1/T2. Methods: Retrospective analysis of 532 cases with PTC in cN0 T1/T2 who underwent CLND between October 2014 and September 2016 in the Department of Thyroid Surgery, the First Affiliated Hospital of the Kunming Medical University. The incidence of central lymph node (CLN) metastasis and risk factors were analyzed. Results: CLN metastasis rates: 41.2% (42/102) in males vs 34.9% (150/430) in females, P=0...
February 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29416604/cunr-scoring-system-for-the-prediction-of-lateral-lymph-node-metastasis-in-papillary-thyroid-carcinoma
#4
Jianyong Lei, Gengpeng Li, Zhihui Li, R X Rong, Jingqiang Zhu
Objective: Our present study aimed to evaluate and compare the number and rate of central lymph node metastases (LNMs) for the prediction of lateral LNM (LLNM) in papillary thyroid carcinoma (PTC) and to develop a scoring system. Results: Capsule invasion, tumor location in the upper portion of the thyroid, an ipsilateral central compartment LNM number ≥3, and an ipsilateral central compartment LNM rate of ≥56% were identified as significant independent predictors of ipsilateral lateral LNM in PTC...
January 2, 2018: Oncotarget
https://www.readbyqxmd.com/read/29398031/does-the-number-of-parathyroid-glands-autotransplanted-affect-the-incidence-of-hypoparathyroidism-and-recovery-of-parathyroid-function
#5
Anping Su, Yanping Gong, Wenshuang Wu, Rixiang Gong, Zhihui Li, Jingqiang Zhu
BACKGROUND: The relationship between the number of parathyroid glands autotransplanted and hypoparathyroidism as well as recovery of parathyroid function is not understood fully. The aim was to ascertain whether the number of autotransplanted glands affected the incidence of hypoparathyroidism and recovery of parathyroid function in long-term follow-up after thyroidectomy. METHODS: A retrospective cohort study included all patients with papillary thyroid carcinoma who underwent first-time total thyroidectomy with central neck dissection between June 2012 and June 2015...
February 2, 2018: Surgery
https://www.readbyqxmd.com/read/29397264/optimizing-treatment-for-children-and-adolescents-with-papillary-thyroid-carcinoma-in-post-chernobyl-exposed-region-the-roles-of-lymph-node-dissections-in-the-central-and-lateral-neck-compartments
#6
Mikhail Fridman, Olga Krasko, Alfred King-Yin Lam
There is lack of data to predict lymph node metastases in pediatric thyroid cancer. The aims are to study (1) the factors affecting the lymph node metastases in children and adolescence with papillary thyroid carcinoma in region exposed to radiation and (2) to evaluate the predictive significance of these factors for lateral compartment lymphadenectomy. Five hundred and nine patients with papillary thyroid carcinoma underwent total thyroidectomy and lymph nodes resection (central and lateral compartments of the neck) surgery during the period of 1991-2010 in Belarus were recruited...
January 9, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29383423/cervical-lymph-node-metastases-of-papillary-thyroid-carcinoma-in-the-central-and-lateral-compartments-in-children-and-adolescents-predictive-factors
#7
C Spinelli, F Tognetti, S Strambi, R Morganti, M Massimino, P Collini
PROBLEM STATEMENT: The aim of our study was to identify predictive factors for lymph node metastases (LNM) in children and adolescents with papillary thyroid carcinoma (PTC) and their impact on survival. METHODS: The authors conducted an Italian multicentric retrospective analysis on 132 pediatric patients (0-18 years old) affected by PTC between 2000 and 2014. The investigated variables were demographic characteristics of the patients, clinicopathological features of PTCs, and persistence/recurrence of disease...
January 30, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29372373/excellent-prognosis-of-central-lymph-node-recurrence-free-survival-for-cn0m0-papillary-thyroid-carcinoma-patients-who-underwent-routine-prophylactic-central-node-dissection
#8
Yasuhiro Ito, Akira Miyauchi, Hiroo Masuoka, Mitsuhiro Fukushima, Minoru Kihara, Akihiro Miya
INTRODUCTION: In Japan, prophylactic central node dissection (p-CND) for papillary thyroid carcinoma (PTC) has been routinely performed in many institutions, including ours (Kuma Hospital, Japan). We evaluated the recurrence to a central lymph node in patients with cN0M0 PTC who underwent routine p-CND. MATERIALS AND METHODS: We enrolled 4301 patients with cN0M0 PTC who underwent an initial surgery between 1987 and 2005 (median age 51 years). The postoperative follow-up periods ranged from 4 to 362 months (median 164 months)...
January 25, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29361659/associations-between-bethesda-categories-and-tumor-characteristics-of-conventional-papillary-thyroid-carcinoma
#9
Vivian Youngjean Park, Eun-Kyung Kim, Jin Young Kwak, Jung Hyun Yoon, Hee Jung Moon
Purpose: The aim of this study was to investigate the associations of Bethesda categories III, V, and VI with the clinical and pathological features of thyroid nodules surgically confirmed as conventional papillary thyroid carcinomas (PTCs). Methods: We analyzed 1,990 consecutive patients diagnosed with conventional PTC at surgery with preoperative Bethesda categories III, V, or VI. We determined the odds ratio (ORs) of the clinical and pathological variables associated with categories III and V, using category VI as the reference...
November 22, 2017: Ultrasonography
https://www.readbyqxmd.com/read/29329789/lateral-lymph-node-metastasis-in-papillary-thyroid-carcinoma-a-systematic-review-and-meta-analysis-for-prevalence-risk-factors-and-location
#10
REVIEW
Yoon Kyoung So, Min-Ji Kim, Seonwoo Kim, Young-Ik Son
BACKGROUND: Lymph node metastasis (LNM) is frequent in papillary thyroid carcinoma (PTC) and is associated with a poor prognosis. Unlike central LNM (CLNM), there are few studies focusing on LLNM. We aimed to investigate the prevalence and the risk factors for LLNM, with its most prevalent sites. METHODS: We performed a comprehensive literature search using the PubMed and EMBASE databases for relevant studies published prior to November 2016 that examined the risk factors for LLNM...
January 9, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29306230/prediction-of-central-lymph-node-metastasis-in-patientswith-thyroid-papillary-microcarcinoma
#11
Şafak Akın, Duygu Yazgan Aksoy, Serkan Akın, Mehmet Kılıç, Fahri Yetişir, Miyase Bayraktar
Background/aim: The purpose of this study was to analyze the clinicopathological characteristics of patients with papillary thyroid carcinoma (PTC) and papillary thyroid microcarcinoma (PTMC) and predictive factors for central lymph node metastasis (CLNM).Materials and methods: Patients diagnosed as having PTC and PTMC were evaluated. Clinical and laboratory parameters were recorded.Results: The mean age at diagnosis was 47.3 +- 11.9 years. Of all 223 patients, 91 (40.8%) had lymph nodes removed, 29 of whom had lymph node metastasis and 24 of whom had only CLNM...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29305712/central-lymph-node-metastasis-in-papillary-thyroid-carcinoma
#12
Ashok R Shaha
No abstract text is available yet for this article.
January 5, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29302495/modified-transoral-endoscopic-thyroid-surgery-for-treatment-of-thyroid-cancer-operative-steps-and-video
#13
Xiao-Wei Peng, Hui Li, Zan Li, Xiao Zhou, Da-Jiang Song, Bo Zhou, Chun-Liu Lv, Wen Peng
In this video we describe a kind of modified transoral endoscopic thyroid surgery involving meticulous dissection of mental nerve. Inclusion criteria are: the diameter of benign tumors such as thyroid cyst, nodular goiter were limited less than 50 mm; the malignant thyroid tumors including follicular and papillary microcarcinoma were defined as a papillary carcinoma <2 cm in diameter and endoscopic surgery required for the patient. A 6 cm arc-shaped incision was designed at oral vestibule. The branches of mental nerves at both sides were identified and exposed carefully...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29238850/risk-factors-for-central-neck-lymph-node-metastases-in-micro-versus-macro-%C3%A2-clinically-node%C3%A2-negative-papillary-thyroid-carcinoma
#14
Luca Sessa, Celestino Pio Lombardi, Carmela De Crea, Serena Elisa Tempera, Rocco Bellantone, Marco Raffaelli
BACKGROUND: Tumor size has been advocated as possible risk factors for occult central lymph node metastases (CNM) in papillary thyroid carcinoma (PTC) patients. This prospective study evaluated factors that could identify patients at higher risk of occult CNM, especially comparing micro-PTC and macro-PTC. METHODS: One hundred and eighty-six patients were recruited. All the patients had cN0 clinically unifocal PTC and underwent total thyroidectomy and bilateral prophylactic central neck dissection...
December 13, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29184876/feasibility-of-sentinel-lymph-node-dissection-using-tc-99m-phytate-in-papillary-thyroid-carcinoma
#15
Se Hyun Paek, Ka Hee Yi, Su-Jin Kim, June Young Choi, Kyu Eun Lee, Young Joo Park, Do-Joon Park, Keon Wook Kang, June-Key Chung
Purpose: Various methods of sentinel lymph node (SLN) biopsy in thyroid cancer have been introduced. Tc-99m phytate as a radiotracer has been successfully utilized for SLN biopsy in breast, cervix, and endometrial cancer. We assessed the feasibility of SLN dissection using Tc-99m phytate in papillary thyroid carcinoma (PTC). Methods: Seventeen patients with PTC were prospectively enrolled. Ultrasound-guided peritumoral injection of 55.5 MBq Tc-99m phytate in 0.25-mL normal saline was performed...
November 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29165434/clinical-analysis-of-hashimoto-thyroiditis-coexistent-with-papillary-thyroid-cancer-in-1392-patients
#16
J Liang, W Zeng, F Fang, T Yu, Y Zhao, X Fan, N Guo, X Gao
Papillary thyroid carcinoma (PTC) is the most common malignant tumour of the thyroid. The effect of the concurrent presence of Hashimoto's thyroiditis (HT) and PTC is still under debate. The aim of this study is to investigate the influence of coexistent HT on prognostic outcomes and the association of coexistent HT with clinicopathological features. The demographic and clinicopathological data of 1,392 patients who underwent surgery in our hospital from 2007 to 2016 was collected and analysed. Among 1,392 PTC patients, the rate of HT was 25...
October 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29162220/clinicopathologic-predictive-factors-of-cervical-lymph-node-metastasis-in-differentiated-thyroid-cancer
#17
Ronghao Sun, Hua Zhang, Kun Liu, Jinchuan Fan, Guojun Li, Xicheng Song, Chao Li
BACKGROUND: Cervical lymph node metastasis (LNM) has been proven to be a predictor for locoregional recurrence in differentiated thyroid carcinoma (DTC). Clinicopathological features could be effective predictive factors for central and lateral LNM of DTC, and provide references to surgeons for cervical neck dissection. METHODS: Retrospective analysis of clinicopathological data was performed on 420 patients who underwent initial surgery from 2010 to 2015. RESULTS: The incidence of central and lateral LNM was calculated...
November 18, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29142854/skin-metastasis-on-the-neck-an-unusual-presentation-of-recurrence-of-papillary-thyroid-carcinoma
#18
Selen Soylu, Akif Enes Arikan, Serkan Teksoz, Murat Ozcan, Yusuf Bukey
Skin metastasis of papillary thyroid carcinoma (PTC) is rare. Here, two cases of skin metastases of PTC are presented. Both of the patients were females, one is 83 and the other is 65 years old. The patients were admitted to the hospital with a movable skin lesion on anterior neck region. Free T3 and T4 levels were in normal levels and TSH levels were low in both patients. The 83-year-old patient underwent total thyroidectomy due to papillary thyroid cancer and received (131)I ablation therapy and then thyroid suppression therapy...
October 2017: Gland Surgery
https://www.readbyqxmd.com/read/29137085/current-trends-of-practical-issues-concerning-micropapillary-thyroid-carcinoma-the-korean-society-of-thyroid-head-and-neck-surgery
#19
Yoon Se Lee, Byung-Joo Lee, Hyun Joon Hong, Kang-Dae Lee
Although several thyroid associations have published various guidelines, controversies especially in cases of micropapillary thyroid cancer (MPTC) still exist. This survey was designed to collect information about diagnostic tests and treatments performed on patients with MPTC and help identify current trends in thyroid surgery.We developed questionnaires about the management methods for MPTC, which were used to identify factors related to indications of fine needle aspiration (FNA), type of surgery, and central lymph node dissection (CLND)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29125111/comparison-of-ultrasound-features-of-primary-metastatic-papillary-thyroid-carcinoma-and-recurrent-persistent-metastatic-cervical-lymph-nodes
#20
Jing-Zhu Xu, Zhi-Yong Liang, Xing-Hua Wang, Xiao-Yi Li, Hong-Feng Liu, Qiong Wu, Ru-Yu Liu, Xiao Yang, Shen-Ling Zhu, Rui-Na Zhao, Xing-Jian Lai, Xiao-Yan Zhang, Xue-Hua Xi, Bo Zhang
Objective To explore the ultrasound features and levels of cervical lymph node metastases in primary and recurrent/persistent papillary thyroid cancer (PTC).Methods We retrospectively analyzed the clinical data of 2181 patients who underwent cervical lymph nodes dissection for PTC from January 1(st) 2015 to January 1(st) 2016.Totally 418 PTC patients (with 622 lymph nodes) who met the inclusion criteria entered the final analysis.Patients who had not received any prior thyroid treatment (surgery with or without radioactive iodine) were categorized as the primary group (352 patients with 527 metastatic lymph nodes),and patients who had received prior treatment (thyroidectomy with or without radioactive iodine) for PTC were categorized as recurrent/persistent group (66 patients with 95 metastatic lymph nodes)...
October 30, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
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