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https://www.readbyqxmd.com/read/28449566/dose-trends-of-aripiprazole-from-2004-to-2014-in-psychiatric-inpatients-in-korea
#1
Young Sup Woo, In Hee Shim, Sang-Yeol Lee, Dae-Bo Lee, Moon-Doo Kim, Young-Eun Jung, Jonghun Lee, Seunghee Won, Duk-In Jon, Won-Myong Bahk
Objective: Although aripiprazole has been widely used to treat various psychiatric disorders, little is known about the adequate dosage for Asian patients in clinical practice. Hence, we evaluated the initial and maximum doses of aripiprazole from 2004 to 2014 to estimate the appropriate dosage for Korean psychiatric inpatients in clinical practice. Methods: In this retrospective study, we reviewed the medical records of patients who were hospitalized in five university hospitals in Korea from March 2004 to December 2014...
May 31, 2017: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28449498/trans-tracheostomy-repair-of-tracheo-esophageal-fistula-under-endoscopic-view-in-a-75-year-old-woman
#2
Francesco Paolo Caronia, Alfonso Reginelli, Mario Santini, Roberto Alfano, Sebastiano Trovato, Ettore Arrigo, Alfonso Fiorelli
Tracheo-esophageal fistula is a life-threatening condition for fatal pulmonary complications. Surgery is the treatment of choice. Unfortunately, the most of patients are unfit for surgery and in these cases there is no a standardized management. Herein, we reported a clinical case of a 75-year-old-woman with a tracheoesophageal fistula related to tracheostomy. The fistula was localized 3.5 cm below the vocal folds and extended 3 cm distally. The patient's poor clinical condition contraindicated surgery while the characteristics of fistula prevented any successfully endoscopic repair with standard methods as application of fibrin glue, clipping, or stenting...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449497/retrosternal-goitre-the-role-of-the-thoracic-surgeon
#3
REVIEW
Diamantis I Tsilimigras, Davide Patrini, Aspasia Antonopoulou, Dimitris Velissaris, Efstratios Koletsis, David Lawrence, Nikolaos Panagiotopoulos
Purpose of this Mini-Review is to evaluate the role of a thoracic surgeon in the surgical management of retrosternal goitre. A cervical approach is sufficient in the majority of the cases. On the other hand, there are cases where a cervical approach is combined with sternotomy or thoracotomy, depending on the position of the goitre, in the anterior or posterior mediastinum. On top of that, different minimally invasive approaches including video-assisted thoracoscopic surgery (VATS) and robotic-assisted surgery (RATS) have been introduced, providing faster recovery, superior manoeuvrability and better aesthetic results...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449489/electromagnetic-navigational-bronchoscopy-with-dye-marking-for-identification-of-small-peripheral-lung-nodules-during-minimally-invasive-surgical-resection
#4
Juan A Muñoz-Largacha, Michael I Ebright, Virginia R Litle, Hiran C Fernando
BACKGROUND: Identification of small peripheral lung nodules during minimally invasive resection can be challenging. Electromagnetic navigational bronchoscopy (ENB) with injection of dye to identify nodules can be performed by the surgeon immediately prior to resection. We evaluated the effectiveness of ENB with dye marking to aid minimally invasive resection. METHODS: Patients with peripheral pulmonary nodules underwent ENB before planned thoracoscopic or robotic-assisted thoracoscopic resection...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449479/early-results-of-the-sorin-%C3%A2-perceval-s-sutureless-valve-systematic-review-and-meta-analysis
#5
Karan Sian, Sheila Li, Daneish Selvakumar, Ross Mejia
BACKGROUND: Minimally invasive aortic valve replacement (MAVR) has demonstrated a benefit with respect to increased patient satisfaction due to minimised pain and earlier recovery. Sutureless valves may benefit MAVR and conventional aortic valve replacement (AVR) by reducing operative times and blood transfusion requirements. The Perceval valve (Sorin, Salluggia, Italy) is a self-expanding prosthesis made from bovine pericardium mounted in a nitinol stent, designed to simplify the implantation of an aortic valve...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449467/clinical-analysis-on-113-patients-with-lung-cancer-treated-by-percutaneous-ct-guided-microwave-ablation
#6
Lou Zhong, Siyuan Sun, Jiahai Shi, Fei Cao, Xiao Han, Xueping Bao, Qingsheng You
BACKGROUND: Lung Cancer is a primary tumor with poor prognosis. For early stage lung cancer, treatment options include surgical resection and microwave techniques. Percutaneous ablative techniques emerged as best therapeutic options for nonsurgical patients. METHODS: The aim of this study was to retrospectively analyze the clinical effect of CT-guided microwave ablation (MWA) treatment for patients with lung cancer who were not eligible for surgical resection. MWA was used to treat the tumor lesion of 113 patients with lung cancer who were in our hospital from Jan, 2013 to Jun, 2015...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449452/robotic-assisted-minimally-invasive-esophagectomy-is-it-advantageous-over-thoracoscopic-esophagectomy
#7
EDITORIAL
Mong-Wei Lin, Jang-Ming Lee
No abstract text is available yet for this article.
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449430/poloxamer-surface-modified-trimethyl-chitosan-nanoparticles-for-the-effective-delivery-of-methotrexate-in-osteosarcoma
#8
Shenglong Li, Yuyuan Xiong, Xiaojing Zhang
The present work is an effort to explore the poloxamer-modified trimethyl chitosan (TMC) encapsulated MTX for osteosarcoma treatment in order to improve the therapeutic efficacy and minimize severe toxicity associated with the clinical usage of MTX. The methotrexate-loaded pluronic-chitosan nanoparticles (MTCN) was nanosized and exhibited a controlled release of drug from the carrier system. The MTCN showed higher accumulation in cell cytoplasm region evident by the high red fluorescence indicating its uptake through energy-dependent endocytosis process...
April 23, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28449270/strong-association-between-cardiorespiratory-fitness-and-serum-lipoprotein-subclass-pattern-in-prepubertal-healthy-children
#9
Geir Kåre Resaland, Tarja Rajalahti, Eivind Aadland, Olav Martin Kvalheim
AIM: To reveal the lipoprotein subclass pattern associated to cardiorespiratory fitness (CRF) in healthy children. METHODS: Serum concentrations of lipoprotein subclasses and concentrations and average particle size of their main classes were quantified in 94 ethnic Norwegian children using high performance liquid chromatography (HPLC). Twenty-four lipoprotein features were used as input to multivariate regression analysis with CRF measured either as peak oxygen consumption (VO2peak) using a continuous treadmill protocol or indirectly by the 10 minute Andersen intermittent running field test...
April 27, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28449263/multi-dice-r-package-for-comparative-population-genomic-inference-under-hierarchical-co-demographic-models-of-independent-single-population-size-changes
#10
Alexander T Xue, Michael J Hickerson
Population genetic data from multiple taxa can address comparative phylogeographic questions about community-scale response to environmental shifts, and a useful strategy to this end is to employ hierarchical co-demographic models that directly test multi-taxa hypotheses within a single, unified analysis while benefiting in statistical power from aggregating datasets. This approach has been applied to classical phylogeographic datasets such as mitochondrial barcodes as well as reduced-genome polymorphism datasets that can yield 10,000s of SNPs, produced by emergent technologies such as RAD-seq and GBS...
April 27, 2017: Molecular Ecology Resources
https://www.readbyqxmd.com/read/28449238/exposure-response-relationship-of-neighbourhood-sanitation-and-children-s-diarrhea
#11
Youngmee Tiffany Jung, Wendy Lou, Yu-Ling Cheng
OBJECTIVES: To assess the association of neighbourhood sanitation coverage with under-five children's diarrheal morbidity, and to evaluate its exposure-response relationship. METHODS: We used the Demographic and Health Surveys (DHS) of 29 developing countries in sub-Saharan Africa and South Asia, conducted between 2010 and 2014. The primary outcome was 2-week incidence of diarrhea in children under 5 years of age (N=300426). We conducted three-level logistic regression analyses and applied cubic splines to assess the trend between neighbourhood-level coverage of improved household sanitation and diarrheal morbidity...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449190/consensus-statement-on-prevention-and-management-of-adverse-effects-following-rejuvenation-procedures-with-hyaluronic-acid-based-fillers
#12
REVIEW
W G Philipp-Dormston, D Bergfeld, B M Sommer, G Sattler, S Cotofana, P Snozzi, U Wollina, K P J Hoffmann, C Salavastru, K Fritz
Facial fillers play an important role in the correction of facial changes associated with ageing. They offer quick treatments in the outpatient setting with minimal subsequent downtime that provide predictable, natural-looking, long-lasting results. Hyaluronic acid soft tissue injectables have established their role as the fillers of choice for patients over the last 2 decades. Hyaluronic acid fillers are rarely associated with adverse reactions, and those that do occur tend to be mild and temporary. However, as with all injected or implanted biomaterials, adverse events can occur and patients must be fully informed of potential risks prior to undergoing treatment...
April 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28449093/opinions-of-lung-cancer-clinicians-on-shared-decision-making-in-early-stage-non-small-cell-lung-cancer%C3%A2
#13
Sahar Mokhles, Alex P W M Maat, Joachim G J V Aerts, Joost J M E Nuyttens, Ad J J C Bogers, Johanna J M Takkenberg
OBJECTIVES: To investigate the opinions of lung cancer clinicians concerning shared decision making (SDM) in early-stage non-small-cell lung cancer patients. METHODS: A survey was conducted among Dutch cardiothoracic surgeons and lung surgeons, pulmonologists and radiation oncologists. The opinions of clinicians on the involvement of patients in treatment decision making was assessed using a 1-5 Likert-type scale. Through open questions, we queried barriers to and drivers of SDM in clinical practice...
April 25, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28449084/perceived-quality-of-life-following-elder-mistreatment-in-rural-india
#14
Srinivasan Chokkanathan, Aravindhan Natarajan
Objectives: Using resilience theory, we examined multiple risks (individual, familial, and mistreatment characteristics) and promotive factors (mastery and social support) associated with perceived quality of life following mistreatment and tested two competing models, compensatory and protective models, to explain the role of promotive factors in the mistreatment-wellbeing linkage. Method: Face-to-face interviews were conducted by administering standardized instruments to 897 randomly selected older adults in rural Tamil Nadu, India...
April 26, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28449004/minimal-detectable-change-for-balance-measurements-in-patients-with-copd
#15
Wajdi Mkacher, Zouhair Tabka, Yassine Trabelsi
PURPOSE: The purpose of this study was to determine the reliability and minimal detectable change (MDC) of various outcome measures that are potentially suitable for evaluating postural control in individuals with chronic obstructive pulmonary disease (COPD). METHODS: This was a test-retest reliability study. Participants with COPD were asked to complete 5 balance assessments, separated by 1 week. The assessments included Timed Up and Go (TUG) Test, Unipodal Stance Test (UST), Tinetti Test, Berg Balance Scale (BBS), and the Activities Balance Confidence (ABC) scale...
May 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28448985/total-skin-electron-beam-therapy-as-part-of-multimodal-treatment-strategies-for-primary-cutaneous-t-cell-lymphoma
#16
Khaled Elsayad, Katharina H Susek, Hans T Eich
Total-skin electron beam therapy (TSEBT) is one of most effective treatments that has been used for cutaneous T-cell lymphoma. Low-dose TSEBT regimens (10-12 Gy) appear to be an effective alternative to conventional-dose TSEBT (30-36 Gy), yielding short-term remission of cutaneous manifestations with minimal toxicity. TSEBT can be administered to patients any time after a diagnosis of mycosis fungoides (MF). Patients requiring rapid relief from cutaneous lesions or symptoms may particularly benefit from TSEBT as an initial therapy...
April 25, 2017: Oncology Research and Treatment
https://www.readbyqxmd.com/read/28448938/choice-modeling-of-system-wide-or-large-scale-environmental-change-in-a-developing-country-context-lessons-from-the-para%C3%A3-ba-do-sul-river
#17
James R Kahn, William F Vásquez, Carlos Eduardo de Rezende
The Rio Paraiba do Sul is a highly polluted river in south central Brazil, that is contaminated by industrial, agricultural and municipal wastes, as well as being impacted by dams, water withdrawals and deforestation in the watershed. Since only very intensive and farreaching environmental policies could result in water quality improvements, valuing the restoration of the river presents many unique challenges. We develop a choice-modeling approach to valuation of the restoration of this river, with general tightening of environmental policy as the policy, and an increase in prices as the payment vehicle...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448860/a-unique-presentation-of-renal-cell-transformation-into-renal-cell-carcinoma-in-subcutaneous-fatty-tissue-post-twenty-year-old-healing-gun-shot-wound-a-case-report
#18
Awadh R Alqahtani, Mohammed A Alqahtani
INTRODUCTION: Renal cell carcinoma (RCC) is the most common malignancy in the genitourinary tract, and is among the 10 most common cancers in both males and females. PRESENTATION OF CASE: We report a case of a 61-year-old male who presented with a cutaneous lesion on his left back side at a site where he had undergone several surgeries - including Left nephrectomy - twenty years ago for a gun-shot wound he sustained which penetrated his abdomen. DISCUSSION: At that time pathology reports turned out to be normal, specially left kidney pathology report which was negative for any malignancy...
March 21, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28448852/reproducibility-of-scapular-muscle-activity-in-isokinetic-shoulder-flexion-and-extension
#19
Monique Wochatz, Sophie Rabe, Martin Wolter, Tilman Engel, Steffen Mueller, Frank Mayer
Repetitive overhead movements have been identified as a main risk factor to develop shoulder complaints with scapular muscle activity being altered. Reliable assessment of muscle activity is essential to differentiate between symptomatic and asymptomatic individuals. Therefore, the present study aimed to investigate the intra- and inter-session reliability of scapular muscle activity during maximal isokinetic shoulder flexion and extension. Eleven asymptomatic adults performed maximum effort isokinetic shoulder flexion and extension (concentric and eccentric at 60°/s) in a test-retest design...
April 13, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28448731/differential-effects-of-circadian-typology-on-sleep-related-symptoms-physical-fatigue-and-psychological-well-being-in-relation-to-resilience
#20
Hong Jun Jeon, Young Rong Bang, Hye Youn Park, Seul A Kim, In-Young Yoon
Various physiological and psychological functions are influenced by circadian typology (CT), which was reported to be related to resilience. However, few studies have assessed the effects of CT in relation to resilience. The aim of the present study was to assess the influence of CT on sleep-related symptoms, physical fatigue and psychological well-being in relation to resilience. The present study included a total of 1794 healthy hospital employees, and they completed the Morningness-Eveningness Questionnaire, Connor-Davidson Resilience Scale, Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Fatigue Severity Scale, Hospital Anxiety and Depression Scale and World Health Organization Quality of Life Scale Abbreviated Version...
April 27, 2017: Chronobiology International
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