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https://www.readbyqxmd.com/read/28532130/effect-of-systematic-control-of-pd-thickness-and-annealing-temperature-on-the-fabrication-and-evolution-of-palladium-nanostructures-on-si-111-via-the-solid-state-dewetting
#1
Sundar Kunwar, Puran Pandey, Mao Sui, Quanzhen Zhang, Ming-Yu Li, Jihoon Lee
Si-based optoelectronic devices embedded with metallic nanoparticles (NPs) have demonstrated the NP shape, size, spacing, and crystallinity dependent on light absorption and emission induced by the localized surface plasmon resonance. In this work, we demonstrate various sizes and configurations of palladium (Pd) nanostructures on Si (111) by the systematic thermal annealing with the variation of Pd thickness and annealing temperature. The evolution of Pd nanostructures are systematically controlled by the dewetting of thin film by means of the surface diffusion in conjunction with the surface and interface energy minimization and Volmer-Weber growth model...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28532105/additive-manufacturing-with-polypropylene-microfibers
#2
Jodie N Haigh, Tim R Dargaville, Paul D Dalton
The additive manufacturing of small diameter polypropylene microfibers is described, achieved using a technique termed melt electrospinning writing. Sequential fiber layering, which is important for accurate three-dimensional fabrication, was achieved with the smallest fiber diameter of 16.4±0.2μm obtained. The collector speed, temperature and melt flow rate to the nozzle were optimized for quality and minimal fiber pulsing. Of particular importance to the success of this method is appropriate heating of the collector plate, so that the electrostatically drawn filament adheres during the direct-writing process...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531915/bone-marrow-stem-cells-anti-liver-fibrosis-potency-inhibition-of-hepatic-stellate-cells-activity-and-extracellular-matrix-deposition
#3
Ervina Julien Sitanggang, Radiana Dhewayani Antarianto, Sri Widia A Jusman, Jeanne Adiwinata Pawitan, Ahmad Aulia Jusuf
Transplantation of bone marrow derived stem cells (BMSCs) has been reported inhibits liver fibrosis. Several in vitro studies by co-culturing BMSCs and hepatic stellate cells (HSCs) indirectly or directly in 2D models showed inhibition of HSC as the key player in liver fibrosis. In this study, we investigated direct effect of BMSCs on HSCs by co-culturing BMSCs and HSCs in 3D model as it represents the liver microenvironment with intricate cell-cell and cell-matrix interactions. Primary isolated rat HSCs and BMSCs were directly co-cultured at 1:1 ratio with hanging drop method...
May 30, 2017: International Journal of Stem Cells
https://www.readbyqxmd.com/read/28531874/sparse-subspace-clustering-for-data-with-missing-entries-and-high-rank-matrix-completion
#4
Jicong Fan, Tommy W S Chow
Many methods have recently been proposed for subspace clustering, but they are often unable to handle incomplete data because of missing entries. Using matrix completion methods to recover missing entries is a common way to solve the problem. Conventional matrix completion methods require that the matrix should be of low-rank intrinsically, but most matrices are of high-rank or even full-rank in practice, especially when the number of subspaces is large. In this paper, a new method called Sparse Representation with Missing Entries and Matrix Completion is proposed to solve the problems of incomplete-data subspace clustering and high-rank matrix completion...
April 25, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/28531823/correlates-of-khat-use-during-pregnancy-a-cross-sectional-study
#5
Motohiro Nakajima, Mulusew G Jebena, Mohammed Taha, Markos Tesfaye, Esayas Gudina, Andrine Lemieux, Richard Hoffman, Mustafa al'Absi
OBJECTIVES: Khat is widely used in East African countries including Ethiopia. A growing body of evidence indicates that long-term khat use is associated with various health consequences. The aim of this study was to examine the magnitude and correlates of khat use in pregnant women. METHODS: This study used a cross-sectional, face-to-face interview design that included 642 pregnant women receiving antenatal care services at primary care centers in Ethiopia. A series of chi-square tests and regression models were conducted to examine whether khat use status (i...
May 9, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28531820/adverse-effects-and-treatment-satisfaction-among-online-users-of-four-antidepressants
#6
Shannon Hughes, Jeffrey Lacasse, Reid Rogers Fuller, Jennifer Spaulding-Givens
Adverse effects (AEs) are an important factor in antidepressant treatment decision-making, though common AE profiles from clinical trial research highlight physical AEs to the neglect of emotional and behavioral AEs. First-hand accounts of antidepressant users on the Internet can supplement AE profiles with information gained from real-world treatment experiences. We examined online user reviews of two older (escitalopram; duloxetine) and two newer (vilazodone; vortioxetine) antidepressants for differences in their AE profiles and determined which categories of AEs were associated with users' satisfaction...
May 16, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28531661/investigation-of-the-thermal-hazardous-effect-of-protective-clothing-caused-by-stored-energy-discharge
#7
Jiazhen He, Yehu Lu, Yan Chen, Jun Li
In addition to direct thermal energy from a heating source, a large amount of thermal energy stored in clothing will continuously discharge to skin after exposure. Investigating the thermal hazardous effect of clothing caused by stored energy discharge is crucial for the reliability of thermal protective clothing. In this study several indices were proposed and applied to evaluate the impact of thermal energy discharge on human skin. The heat discharge from different layers of fabric systems was investigated, and the influences of air gaps and applied compression were examined...
May 10, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28531455/effect-of-serving-size-and-addition-of-sugar-on-the-glycemic-response-elicited-by-oatmeal-a-randomized-cross-over-study
#8
Thomas M S Wolever, B Jan-Willem van Klinken, Susan E Spruill, Alexandra L Jenkins, YiFang Chu, Laura Harkness
BACKGROUND & AIMS: We aimed to determine the impact of serving size and addition of sucrose on the glycemic response elicited by oatmeal. METHODS: We studied 38 healthy subjects (mean ± SD age 40 ± 12 yr, BMI 26.4 ± 3.6 kg/m(2)) on 8 separate days using a randomized, cross-over design. Capillary blood-glucose responses over 2hr after consuming 30, 40 and 60 g Classic Quaker Quick Oats (18, 24 and 36 g available-carbohydrate [avCHO], respectively) and 30 g Oats plus 9 g sucrose (27 g avCHO) were compared with those after avCHO-matched servings of Cream of Rice cereal (Control) (22, 29, 44 and 33 g cereal, respectively)...
December 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531377/following-surgically-assisted-rapid-palatal-expansion-do-tooth-borne-or-bone-borne-appliances-provide-more-skeletal-expansion-and-dental-expansion
#9
Adrien Hamedi-Sangsari, Zahra Chinipardaz, Lee Carrasco
PURPOSE: The aim of this study was to compare outcome measurements of skeletal and dental expansion with bone-borne (BB) versus tooth-borne (TB) appliances after surgically assisted rapid palatal expansion (SARPE). This study was performed to provide quantitative measurements that will help the oral surgeon and orthodontist in selecting the appliance with, on average, the greatest amount of skeletal expansion and the least amount of dental expansion. MATERIALS AND METHODS: A computerized database search was performed using PubMed, EBSCO, Cochrane, Scopus, Web of Science, and Google Scholar on publications in reputable oral surgery and orthodontic journals...
April 25, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28531350/embedded-metal-electrode-for-organic-inorganic-hybrid-nanowire-solar-cells
#10
Han-Don Um, Deokjae Choi, Ahreum Choi, Ji Hoon Seo, Kwanyong Seo
We demonstrate here an embedded metal electrode for highly efficient organic-inorganic hybrid nanowire solar cells. The electrode proposed here is an effective alternative to the conventional bus and finger electrode which leads to a localized short circuit at a direct Si/metal contact and has a poor collection efficiency due to a nonoptimized electrode design. In our design, an Ag/SiO2 electrode is embedded into a Si substrate while being positioned between Si nanowire (SiNW) arrays underneath poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), facilitating suppressed recombination at the Si/Ag interface and notable improvements in the fabrication reproducibility...
May 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28531281/standard-vs-intensified-management-of-heart-failure-to-reduce-healthcare-costs-results-of-a-multicentre-randomized-controlled-trial
#11
P A Scuffham, J Ball, J D Horowitz, C Wong, P J Newton, P Macdonald, J McVeigh, A Rischbieth, N Emanuele, M J Carrington, C M Reid, Y K Chan, S Stewart
Aims: To determine if an intensified form of heart failure management programme (INT-HF-MP) based on individual profiling is superior to standard management (SM) in reducing health care costs during 12-month follow-up (primary endpoint). Methods and results: A multicentre randomized trial involving 787 patients (full analysis set) discharged from four tertiary hospitals with chronic HF who were randomized to SM (n = 391) or INT-HF-MP (n = 396). Mean age was 74 ± 12 years, 65% had HF with a reduced ejection fraction (31...
May 20, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28531255/measurement-repeatability-of-central-and-peripheral-blood-pressures-the-aric-study
#12
Fran Yong, Gerardo Heiss, David Couper, Michelle L Meyer, Susan Cheng, Hirofumi Tanaka
BACKGROUND: Central systolic and pulse pressures are markers of risk for small vessel disease in the brain and kidneys. The extent to which these markers are reproducible in the setting of population studies is less well established. We estimated short-term repeatability of central systolic and pulse pressures, and those of their peripheral measures for comparison. METHODS: Participants aged 65 years and over (n = 79, 56% women) were drawn from the 2011-2013 examination of the ARIC cohort...
May 22, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28531198/a-real-time-traffic-control-method-for-the-intersection-with-pre-signals-under-the-phase-swap-sorting-strategy
#13
Yiming Bie, Zhiyuan Liu, Yinhai Wang
To deal with the conflicts between left-turn and through traffic streams and increase the discharge capacity, this paper addresses the pre-signal which is implemented at a signalized intersection. Such an intersection with pre-signal is termed as a tandem intersection. For the tandem intersection, phase swap sorting strategy is deemed as the most effective phasing scheme in view of some exclusive merits, such as easier compliance of drivers, and shorter sorting area. However, a major limitation of the phase swap sorting strategy is not considered in previous studies: if one or more vehicle is left at the sorting area after the signal light turns to red, the capacity of the approach would be dramatically dropped...
2017: PloS One
https://www.readbyqxmd.com/read/28531196/co-inheritance-of-glucose-6-phosphate-dehydrogenase-deficiency-mutations-and-hemoglobin-e-in-a-kachin-population-in-a-malaria-endemic-region-of-southeast-asia
#14
Zeshuai Deng, Fang Yang, Yao Bai, Lijun He, Qing Li, Yanrui Wu, Lan Luo, Hong Li, Limei Ma, Zhaoqing Yang, Yongshu He, Liwang Cui
Glucose-6-phosphate dehydrogenase (G6PD) deficiency and hemoglobin E (HbE, β26 Glu-Lys) are two common red cell disorders in Southeast Asia. G6PD deficiency produces hemolytic anemia, which can be triggered by certain drugs or infections. HbE is asymptomatic or is manifested as microcytic, minimally hemolytic anemia. The association between G6PD deficiency and HbE is little understood. This study aimed to investigate G6PD deficiency and HbE in a Kachin ethnic group in the China-Myanmar border area. G6PD enzyme activity was measured using a quantitative G6PD assay, G6PD variants genotyped by the SNaPshot assay, and an HbE gene mutation identified by an amplification refractory mutation system and subsequently confirmed by using a reverse dot blot hybridization assay from 100 unrelated individuals in the study area...
2017: PloS One
https://www.readbyqxmd.com/read/28531179/the-gingival-vein-as-a-minimally-traumatic-site-for-multiple-blood-sampling-in-guinea-pigs-and-hamsters
#15
Mariana Valotta Rodrigues, Simone Oliveira de Castro, Cynthia Zaccanini de Albuquerque, Vânia Gomes de Moura Mattaraia, Marcelo Larami Santoro
Laboratory animals are still necessary in scientific investigation and vaccine testing, but while novel methodological approaches are not available for their replacement, the search for new, humane, easy, and painless methods is necessary to diminish their stress and pain. When multiple blood samples are to be collected from hamsters and guinea pigs, the number of available venipuncture sites-which are greatly diminished in these species in comparison with other rodents due to the absence of a long tail-, harasses animal caregivers and researchers...
2017: PloS One
https://www.readbyqxmd.com/read/28531113/retrospective-evaluation-of-metformin-and-or-metformin-plus-a-new-polysaccharide-complex-in-treating-severe-hyperinsulinism-and-insulin-resistance-in-obese-children-and-adolescents-with-metabolic-syndrome
#16
Stefano Stagi, Franco Ricci, Martina Bianconi, Maria Amina Sammarco, Giovanna Municchi, Sonia Toni, Lorenzo Lenzi, Alberto Verrotti, Maurizio de Martino
Background: Pharmacological treatment of obesity and glucose-insulin metabolism disorders in children may be more difficult than in adults. Thus, we evaluate the effects of metformin in comparison with metformin plus a polysaccharide complex (Policaptil Gel Retard(®), PGR) on body weight and metabolic parameters in obese children and adolescents with metabolic syndrome (MetS). Patients and methods: We retrospectively collected 129 children and adolescents (67 girls, 62 boys; median age 12.6 years) treated for a minimum of two years with metformin and low glycemic index (LGI) diet...
May 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28530853/designing-clinical-trials-that-accept-new-arms-an-example-in-metastatic-breast-cancer
#17
Steffen Ventz, Brian M Alexander, Giovanni Parmigiani, Richard D Gelber, Lorenzo Trippa
Purpose The majority of randomized oncology trials are two-arm studies that test the efficacy of new therapies against a standard of care, thereby assigning a large proportion of patients to nonexperimental therapies. In contrast, multiarm studies efficiently share a common control arm while evaluating multiple experimental therapies. A major bottleneck for traditional multiarm trials is the requirement that all therapies-often drugs from different companies-have to be available at the same time when the trial starts...
May 22, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28530831/blue-shifted-green-fluorescent-protein-homologs-are-brighter-than-enhanced-green-fluorescent-protein-under-two-photon-excitation
#18
Rosana S Molina, Tam M Tran, Robert E Campbell, Gerard Glenn Lambert, Anya Salih, Nathan C Shaner, Thomas E Hughes, Mikhail Drobizhev
Fluorescent proteins (FPs) are indispensable markers for two-photon imaging of live tissue, especially in the brains of small model organisms. The quantity of physiologically relevant data collected, however, is limited by heat-induced damage of the tissue due to the high intensities of the excitation laser. We seek to minimize this damage by developing FPs with improved brightness. Among FPs with the same chromophore structure, the spectral properties can vary widely due to differences in the local protein environment...
May 22, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28530803/red-phosphorus-nano-dots-on-reduced-graphene-oxide-as-a-flexible-and-ultra-fast-anode-for-sodium-ion-batteries
#19
Yihang Liu, Anyi Zhang, Chenfei Shen, Qingzhou Liu, Xuan Cao, Yuqiang Ma, Liang Chen, Christian Lau, Tian-Chi Chen, Fei Wei, Chongwu Zhou
Sodium-ion batteries offer an attractive option for potential low cost and large scale energy storage due to the earth abundance of sodium. Red phosphorus is considered as a high capacity anode for sodium-ion batteries with a theoretical capacity of 2596 mAh/g. However, similar to silicon in lithium-ion batteries, several limitations such as large volume expansion upon sodiation/de-sodiation and low electronic conductance have severely limited the performance of red phosphorus anodes. In order to address the above challenges, we have developed a method to deposit red phosphorus nano-dots densely and uniformly onto reduced graphene oxide sheets (P@RGO) to minimize the sodium ion diffusion length and the sodiation/de-sodiation stresses, and the RGO network also serves as electron pathway and creates free space to accommodate the volume variation of phosphorus particles...
May 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28530792/phosphonated-pillar-5-arene-valved-mesoporous-silica-drug-deliv-ery-systems
#20
Xuan Huang, Shanshan Wu, Xiaokang Ke, Xueyuan Li, Xuezhong Du
To explore the diversity and promising applications of pillararene-based molecular machines, phosphonated pillar[5]arenes (PPA[5]) were synthesized to construct novel supramolecular nanovalves for the first time, based on mesoporous silica nanoparticles (MSNs) functionalized with choline and pyridinium moieties, respectively. PPA[5] encircled the choline or pyridinium stalks to construct supramolecular nanovalves for encapsulation of drugs within the MSN pores. PPA[5] showed a high binding affinity for the quaternary ammonium stalks through the host-guest interactions primarily via ion pairing between the phosphonate and quaternary ammonium moieties, in comparison to carboxylated pillar[5]arene (CPA[5]), to minimize premature drug release...
May 22, 2017: ACS Applied Materials & Interfaces
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