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https://www.readbyqxmd.com/read/29241237/delayed-hyperbaric-intervention-in-life-threatening-decompression-illness
#1
Michael Fm Perez, Janet V Ongkeko Perez, April R Serrano, Maravic P Andal, Maria Cc Aldover
Arterial gas embolism is a catastrophic event. Bubbles in the arterial circulation may lodge in the brain and cause infarction in the affected area and/or in a coronary vessel causing acute myocardial ischaemia. There is no well-defined window of time beyond which a response to hyperbaric oxygen is not expected. Major improvement may occur if the patient is treated as soon as possible, but is less likely in divers with severe decompression illness who have delayed intervention. We report on a 51-year-old, male rebreather diver who suffered loss of consciousness and cardiovascular collapse within minutes of a 30-metre deep dive at a remote Micronesian dive site...
December 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/29240656/hospital-acquired-pressure-injury-risk-adjusted-comparisons-in-an-integrated-healthcare-delivery-system
#2
June Rondinelli, Stephen Zuniga, Patricia Kipnis, Lina Najib Kawar, Vincent Liu, Gabriel J Escobar
BACKGROUND: Although healthcare organizations have decreased hospital-acquired pressure injury (HAPI) rates, HAPIs are not eliminated, driving further examination in both nursing and health services research. OBJECTIVE: The objective was to describe HAPI incidence, risk factors, and risk-adjusted hospital variation within a California integrated healthcare system. METHODS: Inpatient episodes were included in this retrospective cohort if patients were hospitalized between January 1, 2013, and June 30, 2015...
January 2018: Nursing Research
https://www.readbyqxmd.com/read/29240626/first-report-of-biventricular-percutaneous-impella-ventricular-assist-device-use-in-pediatric-patients
#3
Javier J Lasa, Daniel A Castellanos, Susan W Denfield, William J Dreyer, Sebastian C Tume, Henri Justino, Athar M Qureshi
There is a growing interest in the use of percutaneously delivered ventricular assist devices (PVAD) in the pediatric patient population. A 16 year old female and 18 year old male both status post heart transplantation presented with evidence of graft rejection and acute severe global systolic and diastolic heart failure necessitating hemodynamic catheterization and inotropic support. Both underwent percutaneous Impella CP LVAD (Abiomed, Danvers, MA) placement with close monitoring of right ventricular function...
December 11, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29240544/expected-time-to-return-to-athletic-participation-after-stress-fracture-in-division-i-collegiate-athletes
#4
Timothy L Miller, Marissa Jamieson, Sonsecharae Everson, Courtney Siegel
BACKGROUND: Few studies have documented expected time to return to athletic participation after stress fractures in elite athletes. HYPOTHESIS: Time to return to athletic participation after stress fractures would vary by site and severity of stress fracture. STUDY DESIGN: Retrospective cohort study. LEVEL OF EVIDENCE: Level 3. METHODS: All stress fractures diagnosed in a single Division I collegiate men's and women's track and field/cross-country team were recorded over a 3-year period...
December 1, 2017: Sports Health
https://www.readbyqxmd.com/read/29239989/a-systematic-review-of-the-association-between-physical-fitness-and-musculoskeletal-injury-risk-part-3-flexibility-power-speed-balance-and-agility
#5
Sarah J de la Motte, Peter Lisman, Timothy C Gribbin, Kaitlin Murphy, Patricia A Deuster
We performed a systematic review and evaluation of the existing scientific literature on the association between flexibility, power, speed, balance, and agility, and musculoskeletal injury (MSK-I) risk in military and civilian populations. MEDLINE, EBSCO, EMBASE, and the Defense Technical Information Center were searched for original studies published from 1970 through 2015 that examined associations between these physical fitness measures (flexibility, power, speed, balance, and agility) and MSK-I. Methodological quality and strength of the evidence were determined following criteria adapted from previously published systematic reviews...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29239852/management-specificities-for-abdominal-pelvic-and-vascular-penetrating-trauma
#6
E Hornez, F Béranger, T Monchal, Y Baudouin, G Boddaert, H De Lesquen, S Bourgouin, Y Goudard, B Malgras, G Pauleau, V Reslinger, N Mocellin, C Natale, L Meyrat, J-P Avaro, P Balandraud, S Gaujoux, S Bonnet
Management of patients with penetrating trauma of the abdomen, pelvis and their surrounding compartments as well as vascular injuries depends on the patient's hemodynamic status. Multiple associated lesions are the rule. Their severity is directly correlated with initial bleeding, the risk of secondary sepsis, and lastly to sequelae. In patients who are hemodynamically unstable, the goal of management is to rapidly obtain hemostasis. This mandates initial laparotomy for abdominal wounds, extra-peritoneal packing (EPP) and resuscitative endovascular balloon occlusion of the aorta (REBOA) in the emergency room for pelvic wounds, insertion of temporary vascular shunts (TVS) for proximal limb injuries, ligation for distal vascular injuries, and control of exteriorized extremity bleeding with a tourniquet, compressive or hemostatic dressings for bleeding at the junction or borderline between two compartments, as appropriate...
November 24, 2017: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/29239735/burns-centre-and-fire-services-what-information-can-be-exchanged-to-manage-the-burn-patient
#7
O Pujji, B Nizar, J Bechar, D North, S Jeffery
AIM: To describe the experience of using a "Burns Extrication Form" at a regional Burns Centre. Communication between the fire services and burns team previously has been regarded as poor. Significant information is collected by the fire services at the scene and this can aid the management of the patient. METHODS: The Burns Extrication Form was devised to provide a clear framework of communication between the two services. Information regarding time frames, exposure to heat & smoke, fire loading (potential severity of a fire in a given space by measuring amount of combustible material in confined space), building construction, chemicals involved is passed to the medical team through this form through a National Health Service mailbox...
November 24, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29239321/should-we-have-a-guard-against-therapeutic-nihilism-for-patients-with-severe-traumatic-brain-injury
#8
Ryan Hirschi, Casey Rommel, Gregory W J Hawryluk
No abstract text is available yet for this article.
November 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29239310/micrornas-as-diagnostic-markers-and-therapeutic-targets-for-traumatic-brain-injury
#9
REVIEW
Bridget Martinez, Philip V Peplow
Traumatic brain injury (TBI) is characterized by primary damage to the brain from the external mechanical force and by subsequent secondary injury due to various molecular and pathophysiological responses that eventually lead to neuronal cell death. Secondary brain injury events may occur minutes, hours, or even days after the trauma, and provide valuable therapeutic targets to prevent further neuronal degeneration. At the present time, there is no effective treatment for TBI due, in part, to the widespread impact of numerous complex secondary biochemical and pathophysiological events occurring at different time points following the initial injury...
November 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29239280/perceived-injustice-and-its-correlates-after-mild-traumatic-brain-injury
#10
Grant L Iverson, Douglas P Terry, Justin E Karr, William Panenka, Noah D Silverberg
Perceived injustice is a belief that one has been treated unfairly, disrespectfully, and is suffering unnecessarily as a result of another person's actions. Perceived injustice predicts chronic disability after musculoskeletal injury, but to our knowledge, has not been empirically studied in people with mild traumatic brain injuries (MTBIs). We examined perceived injustice and its correlates in patients who were slow to recover from MTBI. Patients (N=102) were recruited from four concussion clinics. The sample was on average 41...
December 14, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29239268/a-community-perspective-on-bowel-management-and-quality-of-life-after-spinal-cord-injury-the-influence-of-autonomic-dysreflexia
#11
Jessica A Inskip, Vera-Ellen M Lucci, Maureen S McGrath, Rhonda Willms, Victoria E Claydon
Autonomic dysfunction is common in individuals with spinal cord injury (SCI) and leads to numerous abnormalities, including profound cardiovascular and bowel dysfunction. In those with high level lesions, bowel management is a common trigger for autonomic dysreflexia (AD, hypertension provoked by sensory stimuli below the level of injury). Improving bowel care is integral for enhancing quality of life (QoL). We aimed to describe the relationships between bowel care, AD, and QoL in individuals with SCI. We performed an online community survey of individuals living with SCI (n=287; injury levels C1-sacral)...
December 14, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29238996/quality-management-of-a-massive-transfusion-protocol
#12
John R Hess, Patrick J Ramos, Nina E Sen, Virginia G Cruz-Cody, Erin E Tuott, Max J Louzon, Eileen M Bulger, Saman Arbabi, Monica B Pagano, Ryan A Metcalf
BACKGROUND: Massive transfusion is a response to massive uncontrolled hemorrhage. To be effective, it must be timely and address the patient's needs for blood volume, oxygen transport, and hemostasis. STUDY DESIGN AND METHODS: A review was performed on all activations of the massive transfusion protocol (MTP) in a hospital with large emergency medicine, trauma, and vascular surgery programs. Indications, transfused amounts, and outcomes were determined for each MTP event to determine appropriateness of MTP use...
December 13, 2017: Transfusion
https://www.readbyqxmd.com/read/29238644/impact-of-preoperative-anemia-on-outcomes-in-adults-undergoing-elective-posterior-cervical-fusion
#13
Kevin Phan, Alexander E Dunn, Jun S Kim, John Di Capua, Sulaiman Somani, Parth Kothari, Nathan J Lee, Joshua Xu, James E Dowdell, Samuel K Cho
Study Design: Retrospective analysis of prospectively collected data. Objectives: Few studies have investigated the role of preoperative anemia on postoperative outcomes of posterior cervical fusion. This study looked to investigate the potential relationship between preoperative anemia and postoperative outcomes following posterior cervical spine fusion. Methods: Data from patients undergoing elective posterior cervical fusions between 2005 and 2012 was collected from the American College of Surgeons National Surgical Quality Improvement Program database using inclusion/exclusion criteria...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29238581/a-spicy-status-synthetic-cannabinoid-spice-use-and-new-onset-refractory-status-epilepticus-a-case-report-and-review-of-the-literature
#14
Marc-Alain Babi, Christopher P Robinson, Carolina B Maciel
Synthetic cannabinoids refer to a wide variety of chemicals engineered to bind cannabinoid receptors (CB1 and CB2) and mimic the effects of delta-9-tetrahydrocanabinol. The potential for severe toxicity and limited in vivo data make synthetic cannabinoid intake an important public health and safety concern. Neurologic toxidromes associated with their use include mental status changes, panic attacks, memory distortions, acute psychosis (e.g. paranoia, delusional thoughts), disorganized behavior, and suicidal and homicidal thoughts...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29238575/non-traumatic-isolated-medial-cuneiform-fracture-a-unique-mechanism-of-a-rare-injury
#15
Gabriella Paisan, Steven Magister, Andrew Bridgforth, Seth Yarboro
We report a case of a 23-year-old woman who sustained a stress fracture to the medial cuneiform. Isolated medial cuneiform fractures are extremely rare with less than 10 cases reported in the literature. The patient initially presented to an urgent care facility complaining of right midfoot pain that occurred while running. Radiographs obtained at the time showed no acute abnormality and the patient was told to resume normal activities. Several weeks later, she presented to urgent care again after exercising, this time unable to bear weight and with swelling and ecchymoses of the right foot...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29238501/the-effect-of-perineal-massage-during-the-second-stage-of-birth-on-nulliparous-women-perineal-a-randomization-clinical-trial
#16
Roonak Shahoei, Farzaneh Zaheri, Lila Hashemi Nasab, Fariba Ranaei
Background: Childbirth and puerperium are of the most important periods in women's lives and can affect different aspects of their lives. Objective: To determine the effect of perineal massage in the second stage of labor on perineal lacerations, episiotomy, and perineal pain in nulliparous women. Methods: This randomization clinical trial was conducted at Be'sat Hospital in Sanandaj, Iran, from 2013 to 2014. A total of 195 nulliparous women were included in the study...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29238467/neuroprotection-of-a-sesamin-derivative-1-2-bis-3-methoxyphenyl-methyl-ethane-1-2-dicaroxylic-acid-mmeda-against-ischemic-and-hypoxic-neuronal-injury
#17
Chang-Tsen Hung, Li-Dian Chen, Chien-Wei Hou
Objectives: Stroke may cause severe neuronal damage. The sesamin have been demonstrated to possess neuroprotection by its antioxidant and anti-inflammatory properties. One sesamin derivative was artificially composited, 1, 2-bis [(3-methoxyphenyl) methyl] ethane-1, 2-dicaroxylic acid (MMEDA) had been developed to study its antioxidative activity and neuroprotection. Materials and Methods: The infaction of Sprague Dawley (SD) rats and hypoxia models of BV-2 microglia or PC12 cells were investigated for in vivo and in vitro test respectively...
December 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29238427/hiv-associated-nephropathy-in-africa-pathology-clinical-presentation-and-strategy-for-prevention
#18
REVIEW
Nazik Elmalaika Husain, Mohamed H Ahmed, Ahmed O Almobarak, Sufian K Noor, Wadie M Elmadhoun, Heitham Awadalla, Clare L Woodward, Dushyant Mital
The human immunodeficiency virus (HIV) infection can lead to progressive decline in renal function known as HIV-associated nephropathy (HIVAN). Importantly, individuals of African ancestry are more at risk of developing HIVAN than their European descent counterparts. An in-depth search on Google Scholar, Medline and PubMed was conducted using the terms "HIVAN" and "pathology and clinical presentation", in addition to "prevalence and risk factors for HIVAN", with special emphasis on African countries for any articles published between 1990 and 2017...
January 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29238177/the-mediating-role-of-psychological-symptoms-on-falls-risk-among-older-adults-with-osteoarthritis
#19
Sumaiyah Mat, Chin Teck Ng, Farhana Fadzil, Faizatul Izza Rozalli, Maw Pin Tan
The purpose of this study was to investigate the role of fear of falling (FoF) and psychological symptoms in explaining the relationship between osteoarthritis (OA) symptom severity and falls. Individuals aged ≥65 years with ≥2 falls or ≥1 injurious fall over the past 12 months were included in the falls group, while volunteers aged ≥65 years with no history of falls over 12 months were recruited as controls. The presence of lower extremity OA was determined radiologically and clinically. Severity of symptoms was assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29238069/kynurenic-acid-an-ido-metabolite-controls-tsg-6-mediated-immunosuppression-of-human-mesenchymal-stem-cells
#20
Guan Wang, Kai Cao, Keli Liu, Yueqing Xue, Arthur I Roberts, Fengying Li, Yanyan Han, Arnold B Rabson, Ying Wang, Yufang Shi
Mesenchymal stem cells (MSCs) have been demonstrated to be anti-inflammatory against various immune disorders through several factors, including indoleamine 2,3-dioxygenase (IDO) and TNF-stimulated gene 6 (TSG-6). However, little is known about the necessity for both of these key immunosuppressive factors. Here we employed the mouse lipopolysaccharide (LPS)-induced acute lung injury (ALI) model, and found that IDO is necessary to achieve the effect of human umbilical cord-derived MSC (hUC-MSC)-based treatment on ALI...
December 13, 2017: Cell Death and Differentiation
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