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Nitrous oxygen sedation

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https://www.readbyqxmd.com/read/29702684/a-50-50-mixture-of-nitrous-oxide-oxygen-in-transrectal-ultrasound-guided-prostate-biopsy-a-randomized-and-prospective-clinical-trial
#1
Gabriel da Silva Cazarim, Nubia Verçosa, Leonel Carneiro, Rachel Pastor, Elizabeth Fernandes Vaz da Silva, Louis Barrucand, Ismar Lima Cavalcanti
INTRODUCTION: Transrectal ultrasound-guided biopsy (TUSPB) is the standard method of diagnosis for prostate cancer, and although it is well tolerated by some patients, it presents a discomfort rate of 65 to 90%, which may be associated with pain. For convenience, it is agreed that a method of analgesia and sedation is necessary. For this purpose, this study aimed to evaluate the impact of inhalation of a 50-50% N2O-O2 gas mixture on pain intensity in these patients. MATERIAL AND METHODS: Randomized, double-blinded clinical trial, conducted at Antônio Pedro University Hospital (Hospital Universitário Antônio Pedro), Niterói, RJ, Brazil, containing two groups of 42 patients: a control (C) group, which received 100% oxygen inhalation, and a nitrous oxide (NO) group, which received inhalation of the 50-50% N2O-O2 mixture, self-administered during TUSPB...
2018: PloS One
https://www.readbyqxmd.com/read/29384419/procedural-sedation-and-analgesia-in-trauma-patients-in-an-out-of-hospital-emergency-setting-a-prospective-multicenter-observational-study
#2
Michel Galinski, Laure Hoffman, Delphine Bregeaud, Mounir Kamboua, François-Xavier Ageron, Catherine Rouanet, Jean-Christophe Hubert, Jacques Istria, Mirko Ruscev, Karim Tazarourte, Florence Pevirieri, Frédéric Lapostolle, Frédéric Adnet
BACKGROUND: The quality of procedural analgesia and sedation among trauma patients has not been studied much in the prehospital setting. The main objective of this study was to characterize the quality of procedural analgesia sedation practices in prehospital settings in trauma patients. METHODS: This was an open-label observational prospective multicenter study (January 01, 2012-December 31, 2013). We included all consecutive trauma victims undergoing a potentially painful procedure on the accident scene...
January 31, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29067060/clinical-comparative-study-on-nitrous-oxide-inhalation-versus-intravenous-propofol-and-midazolam-sedation-in-transnasal-gastroscopy
#3
Zhou Xiaoqian, Zhang Tao, Luo Bingsong, Li Jing, Deng Yu, Zhong Weilan
OBJECTIVE: To investigate the Clinical practice value of nitrous oxide inhalation and intravenous propofol and midazolam sedation in transnasal gastroscopy. METHOD: From December 2012 to April 2014, two hundred patients receiving painless transnasal gastroscopy on a voluntary basis were selected in Endoscopy center, The First People's Hospital of GuiYang. Patients were divided into two groups: Group-1 consisted of one hundred patients sedated by nitrous oxide inhalation and Group-2 consisted of one hundred patients sedated by intravenous propofol and midazolam...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28914247/assessment-of-hypoxia-sedation-level-and-adverse-events-occurring-during-inhalation-sedation-using-preadjusted-mix-of-30-nitrous-oxide-70-oxygen
#4
P V Samir, Srinivas Namineni, P Sarada
PURPOSE: To assess the efficacy of nitrous oxide (N2O)-oxygen (O2) inhalation sedation by rapid induction technique using preadjusted mix of 30% N2O and 70% O2 in children. MATERIALS AND METHODS: Sixty children with a treatment plan which included pulp therapy were recruited for the study. Children categorized 3 and 4 of Frankl behavior rating scale and American Society of Anesthesiologists health status I and II were included for the study. Children were distributed into study group (Group-I) and control group (Group-II) by fishbowl randomization...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28858552/nitrous-oxide-inhalation-sedation-through-a-nasal-high-flow-system-the-possibility-of-a-new-technique-in-dental-sedation
#5
Takuro Sanuki, Gaku Mishima, Kensuke Kiriishi, Shinji Kurata, Ichiro Okaysu, Mari Kawai, Toshihiro Watanabe, Mizuki Tachi, Nobuyasu Komasawa, Takao Ayuse
High-flow nasal cannula (HFNC) systems are increasingly used for patients with both acute and chronic respiratory failure because of the clinical effectiveness and patient comfort associated with their use. Recently, HFNC has been used not only as a respiratory support device, but also as a drug delivery system. HFNC is designed to administer heated and humidified inspiratory oxygen flows (100% relative humidity at 37°C). Therefore, HFNC can provide high flows (up to 60 L/min) without discomfort. Moreover, HFNC improves oxygenation by exerting physiologic effects such as (a) dead-space washout and (b) moderate positive airway pressure...
December 0: Anesthesia Progress
https://www.readbyqxmd.com/read/28647109/-meopa-use-practices-in-a-university-hospital-which-conformity
#6
Caroline Victorri-Vigneau, Cécile Paille, Caroline Joyau, Gwenaëlle Veyrac, Claire Cosset, Aline Le Pelletier, Pascale Jolliet, Julien Nizard, Emmanuelle Kuhn
INTRODUCTION: MEOPA (equimolar mixture of oxygen and nitrous oxide) is used for its analgesic and anxiolytic properties in order to obtain conscious sedation of the patient when performing painful care. It is subject to an enhanced pharmacovigilance and addictovigilance monitoring. In this context, it is important to dispose of hospital utilization data. This work aims to assess the compliance of the use of nitrous oxide regarding the recommendations of the summary of product characteristics, in a French university hospital (Nantes) and consider possible improvements...
December 2017: Thérapie
https://www.readbyqxmd.com/read/28629738/nitrous-oxide-versus-oral-sedation-for-pain-management-of-first-trimester-surgical-abortion-a-randomized-study
#7
Rameet H Singh, Maria Montoya, Eve Espey, Lawrence Leeman
OBJECTIVE: The objective of the study was to compare nitrous oxide with oxygen (N2 O/O2 ) to oral hydrocodone/acetaminophen and lorazepam for analgesia during first-trimester surgical abortion. STUDY DESIGN: This double-blind randomized trial assigned women undergoing first-trimester surgical abortion at<11 weeks' gestation to inhaled N2 O/O2 vs. oral sedation for pain management. The N2 O/O2 group received up to 70:30 ratio during the procedure and placebo pills preprocedure; the oral group received inhaled oxygen during the procedure and oral hydrocodone/acetaminophen 5 mg/325 mg and lorazepam 1 mg preprocedure...
August 2017: Contraception
https://www.readbyqxmd.com/read/28556573/initiating-intrapartum-nitrous-oxide-in-an-academic-hospital-considerations-and-challenges
#8
Laura Migliaccio, Robyn Lawton, Lawrence Leeman, Amanda Holbrook
A 50%-50% mixture of nitrous oxide and oxygen has long been used for managing pain during labor in many countries, but only recently has this intrapartum analgesic technique become popular in the United States. Nitrous oxide is considered minimal sedation and a safe pain management alternative. Many facilities are now interested in providing laboring women this analgesic option. The process of establishing use of nitrous oxide in a large institution can be complicated and may seem daunting. This brief report describes the challenges that occurred during the process of initiating nitrous oxide for pain management during childbirth at an academic medical center and discusses various committee roles...
May 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28492195/evaluation-of-nitrous-oxide-oxygen-and-triclofos-sodium-as-conscious-sedative-agents
#9
Priya Subramaniam, K L Girish Babu, Disha Lakhotia
BACKGROUND: Conscious sedation is used in the pediatric dentistry to reduce fear and anxiety in children and promote favorable treatment outcomes. To achieve them, the primary clinical need is for a well-tolerated, effective, and expedient analgesic and sedative agent that is safe to use. AIM: The aim of the present study was to evaluate the efficacy of nitrous oxide-oxygen and triclofos sodium as conscious sedative agents in 5-10-year-old children. METHODOLOGY: Sixty children aged 5-10 years showing anxious, uncooperative, and apprehensive behavior were randomly divided and assigned into two groups (Groups A and B) such that Group A received 40% nitrous oxide-60% oxygen and Group B received triclofos sodium in the dose of 70 mg/kg body weight, given 30 min before the treatment procedure...
April 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28338031/preoperative-analgesia-for-children-and-adolescents-to-reduce-pain-associated-with-dental-treatment
#10
REVIEW
Catherine McCann
Data sourcesCochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, LILACS, ISI Web of Science, ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform.Study selectionRandomised controlled clinical trials of analgesics given before dental treatment versus placebo or no analgesics in children and adolescents up to 17 years of age. Children and adolescents having dental treatment under sedation (including nitrous oxide/oxygen) or general anaesthesia were excluded...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28288298/detection-of-respiratory-adverse-events-in-pediatric-dental-patients-sedated-with-0-75mg-kg-of-midazolam-and-oxygen-by-continuous-pretracheal-auscultation-a-prospective-randomized-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Mostafa Somri, Ibrahim Matter, Christopher Hadjittofi, Naser Hoash, Bian Moaddi, Johnny Kharouba, Constantinos A Parisinos, Benjamin Peretz
PURPOSE: Sedation is becoming more commonplace for pediatric patients undergoing minor procedures. Fortunately, electronic monitors have contributed to a reduction in the associated respiratory adverse events (RAEs). To test the hypothesis that adding the pretracheal stethoscope (PTS) to standard monitoring methods (SMMs) may improve RAE detection in sedated pediatric dental patients, the frequency of RAEs detected by SMMs (i.e. visual observation, capnography, and pulse oximetry) was compared to that detected by SMMs alongside continuous PTS auscultation...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28028373/randomized-controlled-study-of-the-safety-and-efficacy-of-nitrous-oxide-sedated-endoscopic-ultrasound-guided-fine-needle-aspiration-for-digestive-tract-diseases
#12
RANDOMIZED CONTROLLED TRIAL
Cai-Xia Wang, Jian Wang, Yuan-Yuan Chen, Jia-Ni Wang, Xin Yu, Feng Yang, Si-Yu Sun
AIM: To evaluate the efficacy and safety of nitrous oxide-sedated endoscopic ultrasound-guided fine needle aspiration. METHODS: Enrolled patients were divided randomly into an experimental group (inhalation of nitrous oxide) and a control group (inhalation of pure oxygen) and heart rate, blood oxygen saturation, blood pressure, electrocardiogram (ECG) changes, and the occurrence of complications were monitored and recorded. All patients and physicians completed satisfaction questionnaires about the examination and scored the process using a visual analog scale...
December 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27790555/efficacy-and-safety-of-clonidine-as-an-adjuvant-to-bupivacaine-for-caudal-analgesia-in-paediatric-infra-umbilical-surgeries
#13
Samita Priolkar, Shirley Ann D'Souza
INTRODUCTION: Caudal analgesia, has gained popularity in paediatric intraoperative and postoperative pain management, more so with the use of adjuvants to prolong its duration, each of them having various results. Clonidine, an alpha2-adrenergic agonist is being used for its analgesic effects in various doses with 0.25% Bupivacaine. AIM: The study was conducted to compare the analgesic efficacy, haemodynamic safety and side effects of 1 μg/kg Clonidine added to 1 ml/kg of 0...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27747238/inhalation-conscious-sedation-with-nitrous-oxide-and-oxygen-as-alternative-to-general-anesthesia-in-precooperative-fearful-and-disabled-pediatric-dental-patients-a-large-survey-on-688-working-sessions
#14
Angela Galeotti, Annelyse Garret Bernardin, Vincenzo D'Antò, Gianmaria Fabrizio Ferrazzano, Tina Gentile, Valeria Viarani, Giorgio Cassabgi, Tiziana Cantile
Aim. To evaluate the effectiveness and the tolerability of the nitrous oxide sedation for dental treatment on a large pediatric sample constituting precooperative, fearful, and disabled patients. Methods. 472 noncooperating patients (aged 4 to 17) were treated under conscious sedation. The following data were calculated: average age; gender distribution; success/failure; adverse effects; number of treatments; kind of dental procedure undertaken; number of dental procedures for each working session; number of working sessions for each patient; differences between males and females and between healthy and disabled patients in relation to success; success in relation to age; and level of cooperation using Venham score...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27621048/nitrous-oxide-for-pain-management-during-in-office-hysteroscopic-sterilization-a-randomized-controlled-trial
#15
RANDOMIZED CONTROLLED TRIAL
Emily N Schneider, Regan Riley, Eve Espey, Shiraz I Mishra, Rameet H Singh
OBJECTIVES: To evaluate whether inhaled nitrous oxide with oxygen (N2O/O2) is associated with less pain compared to oral sedation for pain management during in-office hysteroscopic sterilization. STUDY DESIGN: This double blinded randomized controlled trial enrolled women undergoing in-office hysteroscopic sterilization. All participants received pre-procedure intramuscular ketorolac and a standardized paracervical block. The intervention group also received N2O/O2 via a nasal mask titrated to a maximum 70%:30% mixture by a nurse during the procedure and placebo pills pre-procedure and the active control group received inhaled O2 during the procedure and 5/325 mg hydrocodone/acetaminophen and 1 mg lorazepam pre-procedure...
March 2017: Contraception
https://www.readbyqxmd.com/read/27513396/the-effects-of-conscious-sedation-with-nitrous-oxide-oxygen-on-cognitive-functions
#16
Sara Samur Ergüven, Ertan Ali Delilbaşi, Berrin İşik, Ferhunde Öktem
BACKGROUND/AIM: The aim of this study was to investigate the effects of conscious sedation with 40% nitrous oxide/oxygen (N2O/O2) on cognitive functions. MATERIALS AND METHODS: Forty dental patients referred to the sedation unit at Gazi University Faculty of Dentistry Department of Oral and Maxillofacial Surgery received a combination of 40% N2O/O2 inhalation for conscious sedation. Psychometric tests were applied three times: before sedation, during sedation, and at the end of the recovery, for assessing cognitive functions...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27501304/preoperative-analgesics-for-additional-pain-relief-in-children-and-adolescents-having-dental-treatment
#17
REVIEW
Paul F Ashley, Susan Parekh, David R Moles, Prabhleen Anand, Laura C I MacDonald
BACKGROUND: Fear of dental pain is a major barrier to treatment for children who need dental care. The use of preoperative analgesics has the potential to reduce postoperative discomfort and intraoperative pain. We reviewed the available evidence to determine whether further research is warranted and to inform the development of prescribing guidelines. This is an update of a Cochrane review published in 2012. OBJECTIVES: To assess the effects of preoperative analgesics for intraoperative or postoperative pain relief (or both) in children and adolescents undergoing dental treatment without general anaesthesia or sedation...
August 8, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27461803/comparative-evaluation-of-diffusion-hypoxia-and-psychomotor-skills-with-or-without-postsedation-oxygenation-following-administration-of-nitrous-oxide-in-children-undergoing-dental-procedures-a-clinical-study
#18
RANDOMIZED CONTROLLED TRIAL
Vineet Inder Singh Khinda, Parvesh Bhuria, Paramjit Khinda, Shiminder Kallar, Gurlal Singh Brar
BACKGROUND: Diffusion hypoxia is the most serious potential complication associated with nitrous oxide. It occurs during the recovery period. Hence, administration of 100% oxygen is mandatory as suggested by many authors. AIM: The aim of this study is to evaluate the occurrence/nonoccurrence of diffusion hypoxia in two groups of patients undergoing routine dental treatment under nitrous oxide sedation when one group is subjected to 7 min of postsedation oxygenation and the second group of the patients is made to breathe room air for the similar period...
July 2016: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/27377113/chloral-hydrate-for-sedation-of-children-with-asthma-during-dental-treatment
#19
I Abdulhamid, M Tremblay, J Stenger, V Tutag Lehr
AIM: We hypothesised that chloral hydrate is safe and effective for sedation during dental treatments for children with mild asthma. We evaluated the safety and efficacy of chloral hydrate by measuring changes in heart rate (HR), transcutaneous oxygen saturation, (SpO2), asthma score, behaviour, types and frequency of adverse reactions associated with chloral hydrate were assessed throughout treatment. MATERIALS AND METHODS: Children (<10 years old) with mild asthma undergoing dental treatments received a single 65 mg/kg oral dose of chloral hydrate liquid 1 hour prior to treatment in an open label trial...
June 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27190950/a-comparison-of-the-effectiveness-of-oral-midazolam-n2o-versus-oral-ketamine-n2o-in-pediatric-patients-an-in-vivo-study
#20
Vasanthi Done, Ravichandrasekhar Kotha, Aron Arun Kumar Vasa, Suzan Sahana, Raghavendra Kumar Jadadoddi, Sushma Bezawada
INTRODUCTION: Most children are casual and moderately agreeable in the dental treatment environment, however some of them show practices that upset the professional and make the protected conveyance of worthy treatment extremely troublesome. For such cases dental practitioner utilizes behavior management techniques. At the point when behavioral administration procedures come up short, some type of pharmacologic sedation or anesthesia may be an important and vital option. Dental sedation is a strategy in which the utilization of a medication or drugs produce(s) a condition of depression of the central sensory system empowering treatment to be completed during which verbal contact with the patient is kept up all through the time of sedation...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
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