Naveen Poonai, Christopher Creene, Ariel Dobrowlanski, Rishika Geda, Lisa Hartling, Samina Ali, Maala Bhatt, Evelyne D Trottier, Vikram Sabhaney, Katie O'Hearn, Rini Jain, Martin H Osmond
OBJECTIVES: The objective of this study was to synthesize indication-based evidence for N2 O for distress and pain in children. STUDY DESIGN: We included trials of N2 O in participants 0-21 years, reporting distress or pain for emergency department procedures. The primary outcome was procedural distress. Where meta-analysis was not possible, we used Tricco et al.'s classification of "neutral" (p ≥ 0.05), "favorable," or "unfavorable" (p < 0...
June 2023: CJEM