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https://www.readbyqxmd.com/read/29453804/probiotics-affect-one-carbon-metabolites-and-catecholamines-in-a-genetic-rat-model-of-depression
#1
Sandra Tillmann, Hussain M Awwad, Amanda R Eskelund, Giulia Treccani, Juergen Geisel, Gregers Wegener, Rima Obeid
SCOPE: Probiotics may influence one-carbon (C1) metabolism, neurotransmitters, liver function markers, or behavior. METHODS AND RESULTS: Male adult Flinders Sensitive Line rats (model of depression, FSL; n = 22) received Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 (10 9 or 10 10 colony-forming units/d) or vehicle for 10 weeks. The controls, Flinders Resistant Line rats (FRL, n = 8), only received vehicle. C1-related metabolites were measured in plasma, urine, and different tissues...
February 17, 2018: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29441359/co-2-leakage-alters-biogeochemical-and-ecological-functions-of-submarine-sands
#2
Massimiliano Molari, Katja Guilini, Christian Lott, Miriam Weber, Dirk de Beer, Stefanie Meyer, Alban Ramette, Gunter Wegener, Frank Wenzhöfer, Daniel Martin, Tamara Cibic, Cinzia De Vittor, Ann Vanreusel, Antje Boetius
Subseabed CO2storage is considered a future climate change mitigation technology. We investigated the ecological consequences of CO2leakage for a marine benthic ecosystem. For the first time with a multidisciplinary integrated study, we tested hypotheses derived from a meta-analysis of previous experimental and in situ high-CO2impact studies. For this, we compared ecological functions of naturally CO2-vented seafloor off the Mediterranean island Panarea (Tyrrhenian Sea, Italy) to those of nonvented sands, with a focus on biogeochemical processes and microbial and faunal community composition...
February 2018: Science Advances
https://www.readbyqxmd.com/read/29438507/bacterial-density-rather-than-diversity-correlates-with-hatching-success-across-different-avian-species
#3
Juan Manuel Peralta-Sánchez, Antonio Manuel Martín-Platero, Laura Wegener-Parfrey, Manuel Martínez-Bueno, Sonia Rodríguez-Ruano, José Antonio Navas-Molina, Yoshiki Vázquez-Baeza, David Martín-Gálvez, Manuel Martín-Vivaldi, Juan Diego Ibáñez-Álamo, Rob Knight, Juan José Soler
Bacterial communities within avian nests are considered an important determinant of egg viability, potentially selecting for traits that confer embryos with protection against trans-shell infection. A high bacterial density on the eggshell increases hatching failure, whether this effect could be due to changes in bacterial community or just a general increase in bacterial density. We explored this idea using intra- and interspecific comparisons of the relationship between hatching success and eggshell bacteria characterized by culture and molecular techniques (fingerprinting and high-throughput sequencing)...
February 9, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29433593/education-practical-training-and-professional-development-for-public-health-practitioners-a-scoping-review-of-the-literature-and-insights-for-sustainable-food-system-capacity-building
#4
Jessica Wegener, Debbie Fong, Cecilia Rocha
OBJECTIVE: Noting the upstream positioning of sustainable food systems (SFS) to multiple global crises, the present review described examples of emerging and promising practices to support SFS-oriented education, practical training (PT) and continuing professional development (CPD) among trainees and public health practitioners (PHP). A secondary objective was to compile the evidence into practical considerations for educators, supervising practitioners and professional associations. DESIGN: A scoping review of the literature published between 2007 and 2017 was conducted in May 2017 using four databases: CINAHL, MEDLINE, Scopus and HSSA, along with bibliography hand-searching and expert consultation...
February 13, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29429412/animal-assisted-intervention-in-the-icu-a-tool-for-humanization
#5
EDITORIAL
Megan M Hosey, Janice Jaskulski, Stephen T Wegener, Linda L Chlan, Dale M Needham
No abstract text is available yet for this article.
February 12, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29427506/anatomical-characterization-of-pdf-tri-neurons-and-peptidergic-neurons-associated-with-eclosion-behavior-in-drosophila
#6
Mareike Selcho, Barbara Mühlbauer, Ronja Hensgen, Sakiko Shiga, Christian Wegener, Kouji Yasuyama
The peptidergic PDF-Tri neurons are a group of non-clock neurons that appear transiently around the time of adult ecdysis (=eclosion) in the fruit fly Drosophila melanogaster. This specific developmental pattern points to a function of these neurons in eclosion or other processes that are active around pupal-adult transition. This article is protected by copyright. All rights reserved.
February 10, 2018: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29405582/long-term-visual-outcome-in-a-danish-population-of-patients-with-idiopathic-intracranial-hypertension
#7
Christina F Hatem, Hanne M Yri, Anne L Sørensen, Marianne Wegener, Rigmor H Jensen, Steffen Hamann
PURPOSE: Idiopathic intracranial hypertension (IIH) is characterized by raised intracranial pressure (ICP), normal cerebrospinal composition and exclusion of alternative causes to increased ICP. The aim of this study was to evaluate long-term visual outcome in a Danish population of IIH patients. METHODS: Retrospective chart review of 41 women diagnosed with IIH between June 2007 and March 2013. Best-corrected visual acuity (BCVA), colour vision, grade and type of visual field (VF) defects and grade of papilloedema according to the Modified Frisén Score were recorded at baseline visit (V0), 2-6 months (V1) and 13 months follow-up visit (V2) from time of diagnosis...
February 6, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29400832/cloaking-of-metal-grid-electrodes-on-lambertian-emitters-by-free-form-refractive-surfaces
#8
Martin F Schumann, Benjamin Fritz, Ralph Eckstein, Uli Lemmer, Guillaume Gomard, Martin Wegener
We discuss invisibility cloaking of metal grid electrodes on Lambertian light emitters by using dielectric free-form surfaces. We show that cloaking can be ideal in geometrical optics for all viewing directions if reflections at the dielectric-air interface are negligible. We also present corresponding white-light proof-of-principle experiments that demonstrate close-to-ideal cloaking for a wide range of viewing angles. Remaining imperfections are analyzed by ray-tracing calculations. The concept can potentially be used to enhance the luminance homogeneity of large-area organic light-emitting diodes...
February 1, 2018: Optics Letters
https://www.readbyqxmd.com/read/29394504/rivaroxaban-plasma-levels-in-acute-ischemic-stroke-and-intracerebral-hemorrhage
#9
David J Seiffge, Georg Kägi, Patrik Michel, Urs Fischer, Yannick Béjot, Susanne Wegener, Marialuisa Zedde, Guillaume Turc, Charlotte Cordonnier, Peter S Sandor, Gilles Rodier, Andrea Zini, Manuel Cappellari, Sabine Schädelin, Alexandros A Polymeris, David Werring, Sebastian Thilemann, Ilaria Maestrini, Eivind Berge, Christopher Traenka, Jochen Vehoff, Gian Marco De Marchis, Monika Kapauer, Nils Peters, Gaia Sirimarco, Leo H Bonati, Marcel Arnold, Philippe A Lyrer, Emmanuel De Maistre, Andreas Luft, Dimtrios A Tsakiris, Stefan T Engelter
OBJECTIVE: Information about Rivaroxaban plasma levels (RivLev) may guide treatment decisions in patients with acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH) taking rivaroxaban. METHODS: In a multicenter registry-based study (Novel-Oral-Anticoagulants-In-Stroke-Patients collaboration;NOACISP;ClinicalTrials.gov:NCT02353585) of patients with stroke while taking rivaroxaban, we compared RivLev in patients with AIS and ICH. We determined how many AIS-patients had RivLev≤100ng/ml, indicating possible eligibility for thrombolysis and how many ICH-patients had RivLev≥75ng/ml, possibly eligible for the use of specific reversal agents...
February 2, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29383313/otologic-manifestations-and-progression-in-patients-with-wegener-s-granulomatosis-a-survey-in-55-patients
#10
Ali Safavi Naini, Jahangir Ghorbani, Sima Montazer Lotfe Elahi, Mohsen Beigomi
Introduction: Granulomatosis with polyangiitis (GPA; also known as Wegener's granulomatosis) is a primary systemic vasculitis involving the ear, nose and throat system (ENT) and lower respiratory tract. Because of the lack of knowledge regarding the clinical findings of GPA due to the limited number of studies, the current study was designed to investigate the prevalence and nature of the otology manifestations in the disease course. Materials and Methods: In the current prospective study, patients with a diagnosis of GPA from 2012-2016 were included...
November 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29381843/efficacy-of-epratuzumab-an-anti-cd22-monoclonal-igg-antibody-in-systemic-lupus-erythematosus-patients-with-associated-sj%C3%A3-gren-s-syndrome-post-hoc-analyses-from-the-embody-trials
#11
Jacques-Eric Gottenberg, Thomas Dörner, Hendrika Bootsma, Valérie Devauchelle-Pensec, Simon J Bowman, Xavier Mariette, Holger Bartz, Marga Oortgiesen, Anthony Shock, Willem Koetse, Catrinel Galateanu, Sabine Bongardt, William A Wegener, David M Goldenberg, Guy Meno-Tetang, Gordana Kosutic, Caroline Gordon
OBJECTIVE: EMBODY 1 (NCT01262365) and EMBODY 2 (NCT01261793) investigated the efficacy and safety of epratuzumab, a CD22-targeted humanized monoclonal IgG1 antibody, in patients with systemic lupus erythematosus (SLE). The studies showed no significant difference from placebo in primary or secondary clinical outcome measures, but did demonstrate B-cell-specific immunological activity. METHODS: Efficacy and safety of epratuzumab were compared between two patient subpopulations randomized in EMBODY 1 & 2: SLE patients with a diagnosis of associated Sjögren's syndrome (aSjS) and without aSjS (non-aSjS patients)...
January 30, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29379274/correlates-of-preferences-for-autonomy-in-long-term-care-results-of-a-population-based-survey-among-older-individuals-in-germany
#12
André Hajek, Thomas Lehnert, Annemarie Wegener, Steffi G Riedel-Heller, Hans-Helmut König
Purpose: Thus far, there is little evidence concerning the factors associated with preferences for autonomy in long-term care. Therefore, the aim of the present study was to investigate the correlates of preferences for autonomy in long-term care among older individuals in Germany. Methods: Data were gathered from a population-based survey of the German population aged ≥65 years in 2015 (N=1,006). Results: Multiple logistic regressions revealed that preferences for freedom of choice for foods were positively associated with living with partner or spouse (OR: 1...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29374638/fluctuating-hypercalcaemia-caused-by-cavitary-mycobacterium-bovis-pulmonary-infection
#13
Darren Patrick Moloney, Liam Chawke, Mairead Therese Crowley, Terence M O'Connor
Hypercalcaemia occurs in many granulomatous diseases. Among them, sarcoidosis and tuberculosis are the most common causes. Other causes include berylliosis, coccidioidomycosis, histoplasmosis, Crohn's disease, silicone-induced granulomas, cat-scratch disease, Wegener's granulomatosis and Pneumocystis carinii pneumonia. Hypercalcaemia in granulomatous disease occurs as a consequence of dysregulated production of 1,25-(OH)2 D3 (calcitriol) by activated macrophages in granulomas. Hypercalcaemia in patients with Mycobacterium tuberculosis infection has been reported in 0%-28% of cases...
January 26, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29372027/lumbar-burner-and-stinger-syndrome-in-an-elderly-athlete
#14
Veronika Wegener, Axel Stäbler, Volkmar Jansson, Christof Birkenmaier, Bernd Wegener
Burner or stinger syndrome is a rare sports injury caused by direct or indirect trauma during high-speed or contact sports mainly in young athletes. It affects peripheral nerves, plexus trunks or spinal nerve roots, causing paralysis, paresthesia and pain. We report the case of a 57-year-old male athlete suffering from burner syndrome related to a lumbar nerve root. He presented with prolonged pain and partial paralysis of the right leg after a skewed landing during the long jump. He was initially misdiagnosed since the first magnet resonance imaging was normal whereas electromyography showed denervation...
January 2018: Korean Journal of Pain
https://www.readbyqxmd.com/read/29371433/staging-hemodynamic-failure-with-blood-oxygen-level-dependent-functional-magnetic-resonance-imaging-cerebrovascular-reactivity-a-comparison-versus-gold-standard-15o-h2o-positron-emission-tomography
#15
Jorn Fierstra, Christiaan van Niftrik, Geoffrey Warnock, Susanne Wegener, Marco Piccirelli, Athina Pangalu, Giuseppe Esposito, Antonios Valavanis, Alfred Buck, Andreas Luft, Oliver Bozinov, Luca Regli
BACKGROUND AND PURPOSE: Increased stroke risk correlates with hemodynamic failure, which can be assessed with (15O-)H2O positron emission tomography (PET) cerebral blood flow (CBF) measurements. This gold standard technique, however, is not established for routine clinical imaging. Standardized blood oxygen-level-dependent (BOLD) functional magnetic resonance imaging+CO2 is a noninvasive and potentially widely applicable tool to assess whole-brain quantitative cerebrovascular reactivity (CVR)...
January 25, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29344320/pyoderma-gangrenosum-associated-granulomatosis-with-polyangitis-a-case-report-and-literature-review
#16
Matthew B Zarraga, Nicole Swenson, Brad Glick
Granulomatosis with polyangitis, formerly known as Wegener's granulomatosis, is a multi-system vasculitis that has a variable clinical presentation. Although uncommon, cutaneous symptoms can be the initial presenting symptom of granulomatosis with polyangitis. We present an unusual case of pyoderma gangrenosum followed by a diagnosis of granulomatosis with polyangitis. We also provide a review of current literature on therapeutic options.
October 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29337388/reactions-of-an-al-p-frustrated-lewis-pair-with-%C3%AE-%C3%AE-unsaturated-carbonyl-compounds-flps-as-efficient-2e-reductants-with-the-formation-of-enolates-a-cis-enediolate-and-an-allene
#17
Werner Uhl, Merten Lange, Jonas C Tendyck, Philipp Wegener, Alexander Hepp, Ernst Ulrich Würthwein
The Al/P based FLP Mes2P-C(AltBu)2=C(H)Ph (1) reacted as an efficient 2e reductant with benzil to afford a cis-enediolate which is coordinated to the FLP via P-O and Al-O bonds and formation of a seven-membered heterocycle (2). The P atom is oxidised from +III to +V. Similar heterocycles (3a to 3f) were formed when 1 was treated with various enones (acroleine, acrylate, acrylamide). The resulting enolates are bound to the FLP via P-C and Al-O bonds. Cyclopropenone gave an adduct (4) with the C=O bond coordinated by P and Al...
January 16, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29329286/is-the-proportional-recovery-rule-applicable-to-the-lower-limb-after-a-first-ever-ischemic-stroke
#18
Janne M Veerbeek, Caroline Winters, Erwin E H van Wegen, Gert Kwakkel
OBJECTIVE: To investigate (a) the applicability of the proportional recovery rule of spontaneous neurobiological recovery to motor function of the paretic lower extremity (LE); and (b) the presence of fitters and non-fitters of this prognostic rule poststroke. When present, the clinical threshold for fitting nor non-fitting would be determined, as well as within-subject generalizability to the paretic upper extremity (UE). METHODS: Prospective cohort study in which the Fugl-Meyer Assessment (FMA)-LE and FMA-UE were measured <72 hours and 6 months poststroke...
2018: PloS One
https://www.readbyqxmd.com/read/29328034/characteristics-of-articular-syndrome-in-systemic-vasculitis
#19
O Syniachenko, O Khaniukov, Ye Yehudina, H Taktashov, K Gashynova
The purpose of the study - investigation the separate joint lesion in systemic vasculitis, their X-ray sonographic characteristics, the correlation of the articular syndrome severity with extra-articular manifestations of the diseases, as well as aspects of the arthritis pathogenesis in this category of patients. The study included 525 patients in the ratio of the examined with Henoch-Schonlen purpura, microscopic polyangiitis, cryoglobulinemic vasculitis, polyarteritis nodosa, Takayasu's arteritis, Wegener's granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis Churg-Strauss as a 7:4:3:1:1:1:1...
December 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29320929/metacognitive-reflection-as-a-moderator-of-attitude-strength-versus-attitude-bolstering-implications-for-attitude-similarity-and-attraction
#20
Vanessa Sawicki, Duane T Wegener
"Strong" attitudes often have greater impact than "weak" attitudes. However, emerging research suggests that weak (uncertain) attitudes can substantially influence thinking or behavior. We propose metacognitive reflection as a moderator between traditional strength patterns and these emerging attitude bolstering patterns. Across six studies, research participants encountered a target person who agreed or disagreed with participants' attitudes. When focused on evaluating the target, attitudes predicted target evaluations better when the attitude was held with certainty (Study 1A), or after certainty had been primed (Studies 2A and 3; strength effects)...
January 1, 2018: Personality & Social Psychology Bulletin
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