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https://www.readbyqxmd.com/read/29778700/paediatric-cystolitholapaxy-through-the-mitrofanoff-monti-channel
#1
J S Thomas, N Smeulders, F Yankovic, S Undre, I Mushtaq, P-J López, P Cuckow
INTRODUCTION: Bladder calculi are a known complication of bladder augmentation. Open cystolithotomy remains the preferred option for treating large or multiple stones. Increasingly, however, minimal access techniques have been used. Reports of Mitrofanoff cystolitholapaxy are rare and have been limited to adults. This study presented a two centre series of children treated by cystolitholapaxy via the Mitrofanoff/Monti channel. MATERIALS AND METHODS: With institutional approval the current study retrospectively reviewed and identified 14 patients, on a prospective database, who underwent Mitrofanoff cystolitholapaxy to treat bladder calculi at two independent institutions in the UK and Chile between 2004 and 2016...
April 4, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29778348/preoperative-antibiotics-in-wrist-arthroscopy
#2
Ryan J Hoel, Marcus J Mittelsteadt, S Andrew Samborski, Deborah C Bohn
PURPOSE: This study seeks to evaluate the need for preoperative antibiotics for wrist arthroscopy. METHODS: A retrospective review of 576 consecutive wrist arthroscopies was performed over a 10-year period at a single ambulatory surgery center. The chart of each included patient was reviewed for postoperative infections following the National Nosocomial Infections Surveillance criteria for diagnosis. RESULTS: Of the 576 wrist arthroscopies reviewed, 324 met the inclusion criteria...
May 16, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29777738/establishment-of-an-efficient-genetic-transformation-method-in-dunaliella-tertiolecta-mediated-by-agrobacterium-tumefaciens
#3
Claudia D Norzagaray-Valenzuela, Lourdes J Germán-Báez, Marco A Valdez-Flores, Sergio Hernández-Verdugo, Luke M Shelton, Angel Valdez-Ortiz
Microalgae are photosynthetic microorganisms widely used for the production of highly valued compounds, and recently they have been shown to be promising as a system for the heterologous expression of proteins. Several transformation methods have been successfully developed, from which the Agrobacterium tumefaciens-mediated method remains the most promising. However, microalgae transformation efficiency by A. tumefaciens is shown to vary depending on several transformation conditions. The present study aimed to establish an efficient genetic transformation system in the green microalgae Dunaliella tertiolecta using the A...
May 16, 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29777366/is-ganglionated-plexus-ablation-effective-for-treating-atrial-fibrillation
#4
Michiko Watanabe, Hiroki Kohno, Yusuke Kondo, Hideki Ueda, Keiichi Ishida, Yusaku Tamura, Shinichiro Abe, Yasunori Sato, Yoshio Kobayashi, Goro Matsumiya
PURPOSE: Very few studies have investigated the efficacy of ganglionated plexus ablation during the conventional maze procedure. In this study, we sought to evaluate its additive effect in reducing recurrent atrial fibrillation after concomitant maze surgery. METHODS: A retrospective study was conducted of 79 patients who underwent Cox maze IV concomitantly with open-heart surgery with (GP group) or without (Maze group) ganglionated plexus mapping. All active ganglionated plexuses were ablated...
May 18, 2018: Surgery Today
https://www.readbyqxmd.com/read/29777355/reduced-port-totally-robotic-distal-subtotal-gastrectomy-with-lymph-node-dissection-for-gastric-cancer-a-modified-technique-using-single-site-%C3%A2-and-two-additional-ports
#5
Won Jun Seo, Taeil Son, Chul Kyu Roh, Minah Cho, Hyoung-Il Kim, Woo Jin Hyung
BACKGROUND: Reduced-port laparoscopic gastrectomy further minimizes the invasiveness of laparoscopic gastrectomy, thereby improving patient quality of life. However, suboptimal ergonomics and visualization are challenges to performing reduced-port laparoscopy. As the application of a robotic surgical system may help overcome these challenges, the present study was performed to evaluate the short-term outcomes of reduced-port totally robotic distal subtotal gastrectomy. METHOD: An initial 40 consecutive gastric cancer patients treated with reduced-port totally robotic distal subtotal gastrectomy with lymph node dissection from February 2016 to February 2017 were retrospectively reviewed...
May 18, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29777317/using-smiles-strings-for-the-description-of-chemical-connectivity-in-the-crystallography-open-database
#6
Miguel Quirós, Saulius Gražulis, Saulė Girdzijauskaitė, Andrius Merkys, Antanas Vaitkus
Computer descriptions of chemical molecular connectivity are necessary for searching chemical databases and for predicting chemical properties from molecular structure. In this article, the ongoing work to describe the chemical connectivity of entries contained in the Crystallography Open Database (COD) in SMILES format is reported. This collection of SMILES is publicly available for chemical (substructure) search or for any other purpose on an open-access basis, as is the COD itself. The conventions that have been followed for the representation of compounds that do not fit into the valence bond theory are outlined for the most frequently found cases...
May 18, 2018: Journal of Cheminformatics
https://www.readbyqxmd.com/read/29776646/international-consortium-of-vascular-registries-consensus-recommendations-for-peripheral-revascularisation-registry-data-collection
#7
Christian-Alexander Behrendt, Daniel Bertges, Nikolaj Eldrup, Adam W Beck, Kevin Mani, Maarit Venermo, Zoltán Szeberin, Gabor Menyhei, Ian Thomson, Georg Heller, Pius Wigger, Gudmundur Danielsson, Giuseppe Galzerano, Cristina Lopez, Martin Altreuther, Birgitta Sigvant, Henrik C Rieß, Art Sedrakyan, Barry Beiles, Martin Björck, Jonathan R Boyle, E Sebastian Debus, Jack Cronenwett
OBJECTIVE/BACKGROUND: To achieve consensus on the minimum core data set for evaluation of peripheral arterial revascularisation outcomes and enable collaboration among international registries. METHODS: A modified Delphi approach was used to achieve consensus among international vascular surgeons and registry members of the International Consortium of Vascular Registries (ICVR). Variables, including definitions, from registries covering open and endovascular surgery, representing 14 countries in ICVR, were collected and analysed to define a minimum core data set and to develop an optimum data set for registries...
May 15, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29775979/-the-open-retromuscular-preperitoneal-mesh-repair-of-the-incisional-lateral-hernia-technique-and-results-of-a-prospective-cohort-study
#8
Friedrich-Eckart Isemer, Ulrich Dietz, Maximilian Ackermann
INTRODUCTION: Surgical approaches to flank hernias have been poorly standardised. The most demanding issues in intermuscular net insertion are the limited area in the dorsal direction and the difficulties in fixing the net to the costal arch or the iliac crest. This is why many different surgical procedures have been published. PATIENTS/MATERIAL AND METHODS: From August 2015 to October 2016, nine patients with a primary incisional lateral hernia received open retromuscular preperitoneal mesh repair...
May 18, 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29775548/open-versus-laparoscopic-approach-for-morgagni-s-hernia-in-infants-and-children-a-systematic-review-and-meta-analysis
#9
Giuseppe Lauriti, Elke Zani-Ruttenstock, Vincenzo D Catania, Lina Antounians, Pierluigi Lelli Chiesa, Agostino Pierro, Augusto Zani
INTRODUCTION: The laparoscopic repair of Morgagni's hernia (MH) has been reported to be safe and feasible. However, it is still unclear whether laparoscopy is superior to open surgery in repairing MH. MATERIALS AND METHODS: Using a defined search strategy, three investigators independently identified all comparative studies reporting data on open and laparoscopic MH repair in patients <18 years of age. Case reports and opinion articles were excluded. Meta-analysis was conducted according to PRISMA guidelines and using RevMan 5...
May 18, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29774548/release-of-tgf-%C3%AE-1-into-root-canals-with-various-final-irrigants-in-regenerative-endodontics-an-in-vitro-analysis
#10
Y Chae, M Yang, J R Kim
AIM: To investigate the release of growth factors into the root canal space after various final irrigants during regenerative endodontic procedures. The residual cytotoxic effect of final irrigants on stem cells from the apical papilla (SCAP) was also examined. METHODOLOGY: To measure the release of TGF-β1, root segments (8mm long) were irrigated with 1.5% NaOCl followed by 20 mL of final irrigants; Saline, 17% EDTA, 10% citric acid, 10% or 37% phosphoric acid...
May 17, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29774363/developmental-dysplasia-of-the-hip-why-are-we-still-operating-on-them-a-plea-for-institutional-newborn-clinical-screening
#11
Wu Chean Lee, Sumanth Kumar Gera, Arjandas Mahadev
INTRODUCTION: Developmental dysplasia of the hip (DDH) is a common orthopaedic condition at birth. Non-surgical management with Pavlik harness can effectively treat DDH with early clinical diagnosis at newborn, but open surgeries continue to be performed. We aimed to elucidate the reasons for this. METHODS: A retrospective review was performed of all open surgeries related to DDH from 2006 to 2016. Patients were either born at our institution (Group 1) or outside of it (Group 2)...
May 18, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29774088/endoscopic-ultrasound-guided-drainage-of-pancreatic-walled-off-necrosis-using-self-expanding-metal-stents-without-fluoroscopy
#12
Barbara Braden, Andreas Koutsoumpas, Michael A Silva, Zahir Soonawalla, Christoph F Dietrich
AIM: To investigate whether endoscopic ultrasound (EUS)-guided insertion of fully covered self-expandable metal stents in walled-off pancreatic necrosis (WOPN) is feasible without fluoroscopy. METHODS: Patients with symptomatic pancreatic WOPN undergoing EUS-guided transmural drainage using self-expandable and fully covered self expanding metal stents (FCSEMS) were included. The EUS visibility of each step involved in the transmural stent insertion was assessed by the operators as "visible" or "not visible": (1) Access to the cyst by needle or cystotome; (2) insertion of a guide wire; (3) introducing of the diathermy and delivery system; (4) opening of the distal flange; and (5) slow withdrawal of the delivery system until contact of distal flange to cavity wall...
May 16, 2018: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29773431/preoperative-frailty-assessment-predicts-loss-of-independence-after-vascular-surgery
#13
Graham W Donald, Amir A Ghaffarian, Farid Isaac, Larry W Kraiss, Claire L Griffin, Brigitte K Smith, Mark R Sarfati, Julie L Beckstrom, Benjamin S Brooke
OBJECTIVE: Frailty, a clinical syndrome associated with loss of metabolic reserves, is prevalent among patients who present to vascular surgery clinics for evaluation. The Clinical Frailty Scale (CFS) is a rapid assessment method shown to be highly specific for identifying frail patients. In this study, we sought to evaluate whether the preoperative CFS score could be used to predict loss of independence after major vascular procedures. METHODS: We identified all patients living independently at home who were prospectively assessed using the CFS before undergoing an elective major vascular surgery procedure (admitted for >24 hours) at an academic medical center between December 2015 and December 2017...
May 14, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29773220/nhs-breast-screening-multidisciplinary-working-group-guidelines-for-the-diagnosis-and-management-of-breast-lesions-of-uncertain-malignant-potential-on-core-biopsy-b3-lesions
#14
S E Pinder, A Shaaban, R Deb, A Desai, A Gandhi, A H S Lee, S Pain, L Wilkinson, N Sharma
Needle core biopsy is considered the histological diagnostic method of choice for screen-detected breast lesions. Although the majority are definitively diagnosed as normal, benign, or malignant, approximately 7% are categorised as B3, of uncertain malignant potential. These include a wide range of lesions with different risks of associated malignancy from <2% to approaching 40% from literature review in UK practice. Historically, these have typically been surgically excised as a diagnostic procedure but the majority are then proven to be benign...
May 15, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29772367/patterns-of-clinical-utilization-of-stereotactic-laser-ablation-sla-an-analysis-of-the-multi-center-prospective-registry
#15
Robert C Rennert, Usman Khan, Stephen B Tatter, Melvin Field, Brian Toyota, Peter E Fecci, Kevin Judy, Alireza M Mohammadi, Patrick Landazuri, Andrew Sloan, Eric Leuthardt, Clark C Chen
BACKGROUND: Stereotactic laser ablation (SLA), also termed laser interstitial thermal therapy (LITT), is a minimally invasive procedure that is increasingly utilized in neurosurgery. We wished to examine how/if SLA is changing the landscape of treatment options for neurosurgical patients. METHODS: Patients undergoing stereotactic laser ablation were prospectively enrolled in the Laser Ablation of Abnormal Neurological Tissue (LAANTERN) registry. Data from the first 100 enrolled patients are presented here...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29772316/a-novel-technique-for-sutureless-proximal-aortic-endograft-revision-in-type-1a-endoleak
#16
Nathaniel Chiang, Samantha M Baird, Ratheesraj Ratinam, Jason Chuen
Management of Type 1A endoleaks can be challenging. In the endovascular era, this condition is expected to become more frequent. Conventionally, surgical explant of the endograft remains the "last resort" surgical treatment when all endovascular or other open options are exhausted. Endograft removal is a difficult and morbid procedure. An alternative technique is described that involves cinching the endograft following disengagement of the proximal fixation hooks. The endograft is re-deployed within a prosthetic aortic replacement graft with an overlapping zone...
May 14, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29772315/long-term-durability-of-infrainguinal-endovascular-and-open-revascularization-for-disabling-claudication
#17
Sikandar Z Khan, Mariel Rivero, Gregory S Cherr, Linda M Harris, Maciej L Dryjski, Hasan H Dosluoglu
OBJECTIVE: Infrainguinal revascularization for disabling claudication (DC) is frequently performed but long term results are still unknown. In this study, we compared clinical outcomes of infrainguinal endovascular (EV) and open interventions for DC following failure of medical management. METHODS: 194 patients with DC (Rutherford category 3) who had open (n=53) or EV (n=141) interventions were grouped as Open-GSV (n=21), Open-Prosthetic (n=32), EV- AB (TASCII A & B) (n=48) and EV-CD (TASCII C & D) (n=93)...
May 14, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29772314/urgent-use-of-gore-excluder-iliac-branch-endoprosthesis-ibe-with-left-transaxillary-approach-for-preservation-of-the-residual-hypogastric-artery-a-case-series
#18
D'Oria Mario, Chiarandini Stefano, Pipitone Marco, Calvagna Cristiano, Riccitelli Francesco, Rotelli Alice, Zamolo Francesca, Griselli Filippo
Preservation of the residual hypogastric artery (HGA) in patients with previous endovascular aortic aneurysm repair (EVAR) may require complex operative strategies. We report an alternative technique to preserve the residual HGA with the Gore Excluder Iliac Branch endoprosthesis (IBE) in urgent situations. MethodsWe report the case of two high-risk patients (unfit for open surgery), with previous EVAR and exclusion of one HGA, treated in emergency setting. Both patients met the anatomical requirements for Gore IBE use...
May 14, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29772044/a-phase-1-open-label-dose-escalation-trial-to-investigate-safety-and-tolerability-of-single-intravitreous-injections-of-icon-1-targeting-tissue-factor-in-wet-amd
#19
John A Wells, Christine R Gonzales, Brian B Berger, Victor H Gonzalez, Brian D Sippy, Gabriela Burian
BACKGROUND AND OBJECTIVE: This phase 1 study evaluated the safety and tolerability of single intravitreous injections (IVIs) of ICON-1 (Iconic Therapeutics, South San Francisco, CA) in patients with neovascular age-related macular degeneration (nAMD). ICON-1 is a modified factor VIIa protein linked with the Fc portion of a human immunoglobulin G1. The molecule binds tissue factor overexpressed on choroidal neovascularization (CNV) in AMD. PATIENTS AND METHODS: Open-label, interventional, dose-escalation trial in 18 patients with CNV due to AMD, with six patients per dose cohort...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29771778/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-using-19-g-needle-for-sarcoidosis
#20
Akshu Balwan
BACKGROUND: Flexible bronchoscopy with endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) is increasingly being used to obtain pathology specimens for diagnosis of sarcoidosis. There is wide variation in reported diagnostic yield in literature. New TBNA needles are available in the market but data are lacking about their diagnostic yield especially for sarcoidosis. This study reports the diagnostic yield of bronchoscopy with EBUS-TBNA using ViziShot FLEX 19-G needle in a series of patients with suspected sarcoidosis...
May 16, 2018: Journal of Bronchology & Interventional Pulmonology
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