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https://www.readbyqxmd.com/read/28808749/bioxmark-for-high-precision-radiotherapy-in-an-orthotopic-pancreatic-tumor-mouse-model-experiences-with-a-liquid-fiducial-marker
#1
S Dobiasch, S Kampfer, R Burkhardt, D Schilling, T E Schmid, J J Wilkens, S E Combs
BACKGROUND AND PURPOSE: High-precision radiotherapy (RT) requires precise positioning, particularly with high single doses. Fiducial markers in combination with onboard imaging are excellent tools to support this. The purpose of this study is to establish a pancreatic cancer mouse model for high-precision image-guided RT (IGRT) using the liquid fiducial marker BioXmark (Nanovi, Kongens Lyngby, Denmark). METHODS: In an animal-based cancer model, different volumes of BioXmark (10-50 µl), application forms, and imaging modalities-cone-beam computer tomography (CBCT) incorporated in either the Small Animal Radiation Research Platform (SARRP) or the small-animal micro-CT Scanner (SkyScan; Bruker, Brussels, Belgium)-as well as subsequent RT with the SARRP system were analyzed to derive recommendations for BioXmark...
August 14, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28807441/whole-body-dose-and-energy-measurements-in-radiotherapy-by-a-combination-of-lif-mg-cu-p-and-lif-mg-ti
#2
Pascal Hauri, Uwe Schneider
PURPOSE: Long-term survivors of cancer who were treated with radiotherapy are at risk of a radiation-induced tumor. Hence, it is important to model the out-of-field dose resulting from a cancer treatment. These models have to be verified with measurements, due to the small size, the high sensitivity to ionizing radiation and the tissue-equivalent composition, LiF thermoluminescence dosimeters (TLD) are well-suited for out-of-field dose measurements. However, the photon energy variation of the stray dose leads to systematic dose errors caused by the variation in response with radiation energy of the TLDs...
August 11, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28797999/long-term-results-of-post-operative-pelvic-image-guided-intensity-modulated-radiotherapy-in-gynecological-malignancies
#3
Rashi Agrawal, Sowmiya Prithiviraj, Dinesh Singh, Vaishali Zamre, Sandeep Agrawal, Arun Kumar Goel, Kanika Gupta, Bala Subramanian
OBJECTIVE: To assess late clinical outcomes with image guided intensity modulated radiotherapy (IG- IMRT) in gynecological malignancies. PATIENTS AND METHODS: We have been practicing IG IMRT for gynecological malignancies since January 2009. Here we are presenting our experience with this modern technique at median follow up of 38 months. During whole treatment bladder filling protocol was followed. Both target volumes and critical structures were contoured according to RTOG guidelines...
May 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28791294/the-use-of-cone-beam-computed-tomography-in-assessing-the-insertion-of-bone-conduction-hearing-implants
#4
Tim George Ate Calon, Martin Lars Johansson, Elske Larissa van den Burg, Anna Maria Louisa Janssen, Marc van Hoof, Robert Jan Stokroos
OBJECTIVE: This study aimed to compare postoperative cone beam CT (CBCT) imaging to implant stability quotient (ISQ) measurement and direct caliper measurements as a suitable technique to assess bone conduction hearing implant (BCHI) seating and insertion depth. METHODS: In vitro, BCHIs were completely (n = 9) and partially inserted (n = 9) in bone blocks of different densities and subsequently scanned. Scans were processed using 3DSlicer 4.3.1 and Mathematica 10...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/28781156/evaluation-of-deformed-image-based-dose-calculations-for-adaptive-radiotherapy-of-nasopharyngeal-carcinoma
#5
Miranda Poon, Catherine Holborn, Ka Fai Cheng, Winky Wing Ki Fung, George Chiu
The ultimate goal of adaptive radiotherapy (ART) is to deliver truly customized radiation treatments. Currently, the quality of cone-beam computed tomography (CBCT) images is still inferior to that of conventional CT images in contour delineations and dose calculations for replanning purposes. This retrospective study aims to evaluate the dosimetric accuracy of using deformed conventional CT images for dose calculations, in the hope of inferring the feasibility of ART using planning CT (PCT) images that deformed to up-to-date CBCT images for patients with nasopharyngeal carcinoma (NPC)...
August 3, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28780900/results-from-a-clinical-trial-evaluating-the-efficacy-of-real-time-body-surface-visual-feedback-in-reducing-patient-motion-during-lung-cancer-radiotherapy
#6
Gareth J Price, Corinne Faivre-Finn, Julia Stratford, Sheena Chauhan, Michelle Bewley, Laura Clarke, Corinne N Johnson, Christopher J Moore
INTRODUCTION: Optical surface measurement devices are a maturing technology in radiotherapy. The challenge for such devices is to demonstrate how they can improve clinical care. We present results from a phase 1 clinical trial designed to test the hypothesis that if presented with live data from a novel optical measurement device, showing their deviation from an ideal radiotherapy treatment position, patients will be able to better control their motion and increase their geometrical conformance...
August 7, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28770316/hepatic-arterial-embolization-using-cone-beam-ct-with-tumor-feeding-vessel-detection-software-impact-on-hepatocellular-carcinoma-response
#7
F H Cornelis, A Borgheresi, E N Petre, E Santos, S B Solomon, K Brown
PURPOSE: Dedicated tumor feeding vessel detection software (TFVDS) using cone beam CT has shown a higher sensitivity to detect tumor feeding vessels during hepatic arterial embolization (HAE) of hepatocellular carcinoma (HCC) compared to 2D imaging. Our primary hypothesis was that HCC tumors treated with HAE guided by a TFVDS would show more complete response (CR) than when treated with 2D imaging alone. Secondary analysis of the impact on X-ray exposure was performed. MATERIALS AND METHODS: Nineteen males and 8 females (median age: 69 year, 46-85) with 44 tumors (median size: 38 mm, 6-100) treated with selective HAE between January 2013 and December 2014 were included...
August 2, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28766828/technical-note-no-increase-in-effective-dose-from-half-compared-to-full-rotation-pelvis-cone-beam-ct
#8
Pascal Hauri, Roger A Hälg, Uwe Schneider
PURPOSE: To image the abdomen of a patient with a gantry mounted imaging system of a linear accelerator, different cone beam computed tomography (CBCT) protocols are available. The whole-body dose of a full rotation abdomen CBCT and a half rotation CBCT was compared. In our clinic, both CBCT protocols are used in daily routine work. METHODS: With an adult anthropomorphic Alderson phantom, the whole-body dose per CBCT scan was measured with thermoluminescence dosimeters...
August 2, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28764971/development-and-validation-of-two-phantoms-for-quality-control-in-cone-beam-ct
#9
Wilson Otto Gomes Batista
This study aimed at the development and validation of the models of phantom: CQ-02-IFBA and CQ-01-IFBA, the first filled with water and the second fully with a solid structure in polymethylmethacrylate (PMMA). Both models allow its use in various models of cone beam computed tomography (CBCT), independent of the size of the field of view. The two phantoms are used to evaluate seven parameters of quality control: intensity or average value of pixels of five different plastics, signal to noise ratio, resolution, low contrast, spatial resolution, the accuracy of distances on the z axis, the geometric distortion and image uniformity...
July 27, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28762152/quantitative-analysis-of-the-relationship-between-maxillary-incisors-and-the-incisive-canal-by-cone-beam-computed-tomography-in-an-adult-japanese-population
#10
Tomonari Matsumura, Yuji Ishida, Ayako Kawabe, Takashi Ono
BACKGROUND: In setting goals for orthodontic treatment, determining the morphologies of the alveolar bone and maxillary incisor root is important for avoiding root resorption, dehiscence, and fenestration. This study aimed to analyze the configurational relationships among maxillary incisors, the alveolar border, and the incisive canal by cone-beam computed tomography (CBCT). METHODS: Cone-beam CT images of 93 orthodontic patients were evaluated for length of the incisive canal (L); angles between the palatal plane and the maxillary alveolar border (θ1), the incisive canal (θ2), and maxillary incisor (θ3); distance from the left maxillary incisor to the incisive canal (D); and cross-sectional areas of the incisive canal (CSAs) at three vertical levels...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28760037/mini-open-anterior-approach-for-cervicothoracic-junction-fracture-technical-note
#11
Junichi Ohya, David P Bray, Stephen T Magill, Todd D Vogel, Sigurd Berven, Praveen V Mummaneni
Elderly patients with diffuse idiopathic skeletal hyperostosis are at high risk for falls, and 3-column unstable fractures present multiple challenges. Unstable fractures across the cervicothoracic junction are associated with significant morbidity and require fixation, which is commonly performed through a posterior open or percutaneous approach. The authors describe a novel, navigated, mini-open anterior approach using intraoperative cone-beam CT scanning to place lag screws followed by an anterior plate in a 97-year-old patient...
August 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28758916/effect-of-a-particulate-and-a-putty-like-tricalcium-phosphate-based-bone-grafting-material-on-bone-formation-volume-stability-and-osteogenic-marker-expression-after-bilateral-sinus-floor-augmentation-in-humans
#12
Christine Knabe, Doaa Adel Khattab, Esther Kluk, Rainer Struck, Michael Stiller
This study examines the effect of a hyaluronic acid (HyAc) containing tricalcium phosphate putty scaffold material (TCP-P) and of a particulate tricalcium phosphate (TCP-G) graft on bone formation, volume stability and osteogenic marker expression in biopsies sampled 6 months after bilateral sinus floor augmentation (SFA) in 7 patients applying a split-mouth design. 10% autogenous bone chips were added to the grafting material during surgery. The grain size of the TCP granules was 700 to 1400 µm for TCP-G and 125 to 250 µm and 500 to 700 µm (ratio 1:1) for TCP-P...
July 29, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/28756305/age-assessment-in-canine-and-premolar-by-cervical-axial-sections-of-cone-beam-computed-tomography
#13
Hichem Nemsi, Nidhal Haj Salem, Ines Bouanene, Sami Ben Jomaa, Meriem Belhadj, Mohamed Amin Mosrati, Abir Aissaoui, Faten Ben Amor, Ali Chadly
Age estimation in adults is a challenge in both anthropological and forensic situations compared to sub-adults age estimation. The present study explored, for the first time, the cervical zone of single rooted teeth. The deposition of secondary dentin is responsible for a decrease in the volume of the dental pulp cavity with aging, and therefore is often used as an age indicator. The current study aimed at estimating the chronological age among adults by measuring the pulp/dentin area ratio (physiological ratio) by axial sections at cervical region of maxillary canine and mandibular second premolar...
July 21, 2017: Legal Medicine
https://www.readbyqxmd.com/read/28753537/comparison-of-different-approaches-for-measuring-tibial-cartilage-thickness
#14
Jennifer Maier, Marianne Black, Serena Bonaretti, Bastian Bier, Bjoern Eskofier, Jang-Hwan Choi, Marc Levenston, Garry Gold, Rebecca Fahrig, Andreas Maier
Osteoarthritis is a degenerative disease affecting bones and cartilage especially in the human knee. In this context, cartilage thickness is an indicator for knee cartilage health. Thickness measurements are performed on medical images acquired in-vivo. Currently, there is no standard method agreed upon that defines a distance measure in articular cartilage. In this work, we present a comparison of different methods commonly used in literature. These methods are based on nearest neighbors, surface normal vectors, local thickness and potential field lines...
July 28, 2017: Journal of Integrative Bioinformatics
https://www.readbyqxmd.com/read/28752713/-midpalatal-cortex-osteotomy-assisted-rapid-maxillary-expansion-for-correction-of-maxillary-transverse-deficiency-in-young-adults
#15
Weng Luxi, Song Xiaojia, L I Juan, Liu Pengruofeng, Lin Jun
Objective: To evaluate the application of midpalatal cortex osteotomy assisted rapid maxillary expansion for correction of maxillary transverse deficiency in young adults. Methods: Fourteen young adult patients with maxillary transverse deficiency were treated with midpalatal cortex osteotomy assisted rapid maxillary expansion. Lateral cephalogram and cone beam CT (CBCT) were taken before and 3 months after treatment. The width of basal bone, arch of maxilla and the torque of anchorage teeth were compared before and after treatment...
March 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28749697/tld-measurements-and-monte-carlo-calculations-of-head-and-neck-organ-and-effective-doses-for-cone-beam-computed-tomography-using-3d-accuitomo-170
#16
Marina Ernst, Peter Manser, Karl Dula, Werner Volken, Marco Stampanoni, Michael Fix
OBJECTIVES: In dentistry the use of Cone Beam Computed Tomography (CBCT) has steadily increased over the last few years. The aim of this study was to measure organ doses and to perform dose calculations based on Monte Carlo (MC) simulations to work out a basis for full 3D dose calculations for any patient examination performed with the machine used in this study. METHODS: TLD-100 LiF detectors were placed at 71 measurement positions on the surface and within a RT-Humanoid phantom to cover all relevant radiosensitive organs and tissues...
July 27, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28749172/no-differences-in-radiological-changes-after-3d-conformal-vs-vmat-based-stereotactic-radiotherapy-for-early-stage-non-small-cell-lung-cancer
#17
Serena Badellino, Jacopo Di Muzio, Giulia Schivazappa, Alessia Guarneri, Riccardo Ragona, Sara Bartoncini, Elisabetta Trino, Andrea Riccardo Filippi, Paolo Fonio, Umberto Ricardi
OBJECTIVES: To compare patterns of acute and late radiological lung injury following either 3D or image-guided VMAT stereotactic radiotherapy for stage I Non-Small-Cell Lung Cancer (NSCLC). METHODS: We included 148 patients from a prospective mono-institutional SBRT series (time interval 2004-2014), treated with prescription BED10 Gy (at 80%) in the range 100-120 Gy. The first 95 patients (2004-2010) were planned with 3D-CRT, with a stereotactic body frame. The second cohort (2010-2014) included 53 patients, planned with volumetric IMRT on a smaller PTV generated from a patient's specific ITV, with a frameless approach through cone-beam CT guidance...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28748521/clinical-outcome-of-alveolar-ridge-augmentation-with-individualized-cad-cam-produced-titanium-mesh
#18
K Sagheb, E Schiegnitz, M Moergel, C Walter, B Al-Nawas, W Wagner
BACKGROUND: The augmentation of the jaw has been and continues to be a sophisticated therapy in implantology. Modern CAD-CAM technologies lead to revival of old and established augmentation techniques such as the use of titanium mesh (TM) for bone augmentation. The aim of this retrospective study was to evaluate the clinical outcome of an individualized CAD-CAM-produced TM based on the CT/DVT-DICOM data of the patients for the first time. METHODS: In 17 patients, 21 different regions were augmented with an individualized CAD-CAM-produced TM (Yxoss CBR®, Filderstadt, Germany)...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28747616/assessment-of-non-invasive-chronic-fungal-rhinosinusitis-by-cone-beam-ct-comparison-with-multidetector-ct-findings
#19
Tomohiko Yamauchi, Akiko Tani, Shuji Yokoyama, Hiroshi Ogawa
OBJECTIVE: To investigate the accuracy of cone beam CT (CBCT) to diagnose non-invasive chronic fungal rhinosinusitis. METHODS: Preoperative CT evaluation of non-invasive chronic fungal rhinosinusitis was performed by CBCT (3D Accuitomo 170(®)) and traditional multidetector CT (MDCT) (Aquilion 32(®)) in 13 and 38 patients with non-invasive chronic fungal maxillary sinusitis, respectively, in different facilities. Detection of intrasinus calcification was compared between these two groups...
July 26, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28747271/diagnostic-accuracy-of-split-bolus-single-phase-contrast-enhanced-cone-beam-ct-for-the-detection-of-liver-tumors-before-transarterial-chemoembolization
#20
Martin Jonczyk, Julius Chapiro, Federico Collettini, Dominik Geisel, Dirk Schnapauff, Florian Streitparth, Thomas Schmidt, Bernd Hamm, Bernhard Gebauer, Gero Wieners
PURPOSE: To evaluate detectability of hepatocellular carcinoma (HCC) using split-bolus cone-beam CT in intraindividual comparison between cone-beam CT and contrast-enhanced MR imaging. MATERIALS AND METHODS: In a retrospective, single-center study, 28 patients with 85 HCC tumors were treated with transarterial chemoembolization between May 2015 and June 2016. All patients underwent arterial and hepatobiliary phase (HBP) MR imaging within 1 month before transarterial chemoembolization...
July 23, 2017: Journal of Vascular and Interventional Radiology: JVIR
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