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https://www.readbyqxmd.com/read/29150379/changes-in-maxillofacial-morphology-and-velopharyngeal-function-with-two-stage-maxillary-distraction-mandibular-setback-surgery-in-patients-with-cleft-lip-and-palate
#1
T Susami, Y Mori, K Ohkubo, M Takahashi, Y Hirano, H Saijo, T Takato
Maxillary distraction is increasingly used for the correction of severe maxillary retrusion in patients with cleft lip and palate. However, control of the maxillary movement is difficult, and the need to wear visible distractors for a long period of time causes psychosocial problems. A two-stage surgical approach consisting of maxillary distraction and mandibular setback was developed to overcome these problems. In this study, changes in maxillofacial morphology and velopharyngeal function were examined in 22 patients with cleft lip and palate who underwent this two-stage approach...
November 14, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29145771/topical-simvastatin-gel-as-a-novel-therapeutic-modality-for-palatal-donor-site-wound-healing-following-free-gingival-graft-procedure
#2
Marwa Madi, Abeer Kassem
OBJECTIVE: Autogenous soft-tissue grafting is a commonly used procedure nowadays in dentistry. However, the prolonged healing time needed for the donor site leads to increase the patient's pain and discomfort. Statin has been observed to be beneficial in reducing bacterial burden, improving epithelization and wound healing. The aim of this study was to evaluate intra-oral topical application of simvastatin/chitosan gel (10 mg/mL) over the palatal donor site following free gingival graft (FGG) procedure...
November 16, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29145544/blast-sms-text-messaging-to-facilitate-enrollment-for-cleft-lip-and-palate-surgery-in-zimbabwe
#3
David A Shaye, Faith C Muchemwa, Aleck Gonga, Travis T Tollefson
No abstract text is available yet for this article.
November 16, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29142654/correlation-between-nasoalveolar-molding-and-surgical-aesthetic-functional-and-socioeconomic-outcomes-following-primary-repair-surgery-a-systematic-review
#4
REVIEW
Sophie Maillard, Jean-Marc Retrouvey, Mairaj K Ahmed, Peter J Taub
Objectives: The authors performed a systematic review to evaluate the potential beneficial effects of the nasoalveolar molding appliance on nonsyndromic unilateral clefts of the lip and/or palate prior to primary lip repair. Material and Methods: A literature search was performed using three electronic databases (PubMed, Embase, Web of Science) and three journals ("Cleft Palate-Craniofacial Journal", "Plastic and Reconstructive Surgery Journal" and "American Journal of Orthodontics and Dentofacial Orthopaedic") from January 1980 to April 2017...
July 2017: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29140732/a-rare-form-of-ankyloblepharon-filiforme-adnatum-associated-with-the-hay-wells-syndrome-and-a-c-1709t-c-mutation-on-the-tp63-gene
#5
Michal Koubek, Kristýna Strakošová, Juraj Timkovič, Dagmar Grečmalová, Aneta Orlíková, Hana Burčková, Hana Wiedermannová, Petr Mašek
INTRODUCTION: Ankyloblepharon filiforme adnatum associated with Hay-Wells syndrome is a rare congenital disease caused by mutations in TP63 gene on the 3q27 chromosome. Here, we report a case of a new-born suffering from this syndrome in whom we detected a mutation c.1709T>C not previously included in the Ensemble database. CASE DESCRIPTION: A girl delivered in the 34th week of gestation from a physiological pregnancy was born with extensive burn-like skin defects, ankyloblepharon filiforme adnatum, palate cleft, onychodystrophy of all limbs and syndactyly of toes...
November 15, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29134168/anatomical-region-segmentation-for-objective-surgical-skill-assessment-with-operating-room-motion-data
#6
Yangming Li, Randall A Bly, R Alex Harbison, Ian M Humphreys, Mark E Whipple, Blake Hannaford, Kris S Moe
Background  Most existing objective surgical motion analysis schemes are limited to structured surgical tasks or recognition of motion patterns for certain categories of surgeries. Analyzing instrument motion data with respect to anatomical structures can break the limit, and an anatomical region segmentation algorithm is required for the analysis. Methods  An atlas was generated by manually segmenting the skull base into nine regions, including left/right anterior/posterior ethmoid sinuses, frontal sinus, left and right maxillary sinuses, nasal airway, and sphenoid sinus...
December 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29119091/alar-width-changes-due-to-surgically-assisted-rapid-palatal-expansion-a-meta-analysis
#7
REVIEW
Kevin C Lee, Michael Perrino
A major objective of orthognatic surgery is the aesthetic outcome. Treatments only correcting for dentoskeletal deformities are not sufficient for optimal facial results because undesirable soft tissue changes may accompany skeletal manipulations. The primary objective of this study was to investigate alar base width (ABW) changes a minimum of 6 months following surgically-assisted rapid palatal expansion (SARPE). The following electronic databases and citation indices were searched: PubMed, Cochrane Library, Scopus, Web of Science, Embase, and Virtual Health Library...
October 2017: Journal of Orthodontic Science
https://www.readbyqxmd.com/read/29109837/comparing-plastic-surgery-and-otolaryngology-management-in-cleft-care-an-analysis-of-4-999-cases
#8
Kevin T Jubbal, Dmitry Zavlin, Shola Olorunnipa, Anthony Echo, Edward P Buchanan, Larry H Hollier
Care for patients with cleft lip and palate is best managed by a craniofacial team consisting of a variety of specialists, including surgeons, who are generally plastic surgeons or otolaryngologists trained in the United States. The goal of this study was to compare the surgical approaches and management algorithms of cleft lip, cleft palate, and nasal reconstruction between plastic surgeons and otolaryngologists. We performed a retrospective analysis of the American College of Surgeons' National Surgical Quality Improvement Program Pediatric database between 2012 and 2014 to identify patients undergoing primary repair of cleft lip, cleft palate, and associated rhinoplasty...
December 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/29106778/evolution-of-soft-palate-surgery-techniques-for-obstructive-sleep-apnea-patients-a-comparative-study-for-single-level-palatal-surgeries
#9
Mohamed S Rashwan, Filippo Montevecchi, Giovanni Cammaroto, Mohamed Badr El Deen, Nagi Iskander, Diaa El Hennawi, Mohammed El Tabbakh, Giuseppe Meccariello, Riccardo Gobbi, Francesco Stomeo, Claudio Vicini
OBJECTIVES: to compare the results of tissue preservation techniques of soft palate surgeries including expansion sphincter pharyngoplasty (ESP) and barbed reposition pharyngoplasty (BRP) for patients suffering from obstructive sleep apnea (OSA) with the traditional uvulopalatopharyngoplasty (UPPP). DESIGN: interventional comparative study. SETTING: Morgagni- Pierantoni Hospital. PARTICIPANTS: seventy five patients were included in the study, divided into three groups with 25 patients per group: UPPP, ESP or BRP...
November 6, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29104056/taste-evaluation-of-a-novel-midazolam-tablet-for-pediatric-patients-in-vitro-drug-dissolution-in-vivo-animal-taste-aversion-and-clinical-taste-perception-profiles
#10
Laurence C Cheung, Minh Nguyen, Edith Tang, Britta S von Ungern Sternberg, Sam Salman, Catherine Tuleu, Abeer H A Mohamed Ahmed, Jessica Soto, Lee Yong Lim
Harmonized methodologies are urgently required for the taste evaluation of novel pediatric medicines. This study utilized in vitro, in vivo and clinical data to evaluate the palatability of a novel midazolam chocolate tablet. In vitro dissolution experiments showed the crushed tablet to release within 5 min 1.68 mg of midazolam into simulated saliva. This translated to a drug level of 0.84 mg/ml in the oral cavity, which would be higher than the midazolam bitterness detection threshold concentration of 0...
November 11, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29095187/defining-the-role-of-free-flaps-for-transoral-robotic-surgery
#11
Kyle M Hatten, Robert M Brody, Gregory S Weinstein, Jason G Newman, Andres M Bur, Ara A Chalian, Bert W OʼMalley, Christopher H Rassekh, Steven B Cannady
BACKGROUND: Transoral surgical techniques for oropharyngeal tumors have been widely accepted, yet often results in a significant functional deficit. Current reports on the safety, feasibility, and swallowing performance after microvascular reconstruction are limited to small volume case series. MATERIALS AND METHODS: Retrospective review of 42 consecutive patients, between December 2013 and May 2016, who underwent transoral robotic surgery oropharyngectomy followed by microvascular reconstruction...
October 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29094197/let-s-know-from-our-patients-ppops-score-for-palate-surgery-evaluation-a-pilot-study
#12
Mohamed S Rashwan, Filippo Montevecchi, Elisabetta Firinua, Sandeep Dachuri, Hayfa Obaidat, Riccardo Gobbi, Giovanni Cammaroto, Simona Nuzzo, Claudio Vicini
AIM: To introduce a questionnaire that can be used to assess the post-operative perception of the patients after palatal surgery. The questionnaire was named: Palate Post-Operative Problems Score (PPOPS). STUDY DESIGN: Pilot study. PATIENTS AND METHODS: The study was performed at Morgagni-Pierantoni hospital, Forli. Forty patients suffering from obstructive sleep apnea (OSA) who performed either expansion sphincter pharyngoplasty (ESP) or barbed reposition pharyngoplasty (BRP) in our hospital were divided into two groups, 20 patients per group...
November 1, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29084117/a-review-of-randomized-controlled-trials-in-cleft-and-craniofacial-surgery
#13
Jonathan M Bekisz, Elise Fryml, Roberto L Flores
This study presents a systematic review of randomized controlled trials (RCTs) in cleft and craniofacial surgery. All studies reporting on RCTs in cleft and craniofacial surgery were identified on PubMed using the search terms "cleft," "velopharyngeal insufficiency," "velopharyngeal dysfunction," "nasoalveolar molding," "gingivoperiosteoplasty," "Pierre Robin sequence," "craniofacial," "craniosynostosis," "craniofacial microsomia," "hemifacial microsomia," "hypertelorism," "Le Fort," "monobloc," "distraction osteogenesis," "Treacher Collins," and "Goldenhar...
October 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29084116/role-of-swallowing-function-of-tracheotomised-patients-in-major-head-and-neck-cancer-surgery
#14
Alexander K Bartella, Mohammad Kamal, Sean Berman, Timm Steiner, Dirk Frölich, Frank Hölzle, Bernd Lethaus
INTRODUCTION: Tracheotomy is a frequent procedure in extended head and neck cancer surgery and known to be a risk factor for prolonged hospitalization. The authors hypothesized that the clinical course and delayed decannulation of patients are not only influenced by airway narrowing, but also by a compromised postoperative swallowing function. MATERIAL AND METHODS: The investigators implemented a retrospective cohort study. The sample was composed of a tertiary care center patients who underwent major head and neck cancer surgery, each receiving a tracheostomy...
October 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29082462/low-level-laser-therapy-with-940%C3%A2-nm-diode-laser-on-stability-of-dental-implants-a-randomized-controlled-clinical-trial
#15
Parviz Torkzaban, Shahin Kasraei, Sara Torabi, Maryam Farhadian
Low-level laser therapy (LLLT) is a non-invasive modality to promote osteoblastic activity and tissue healing. The aim of this study was to evaluate the efficacy of LLLT for improvement of dental implant stability. This randomized controlled clinical trial was performed on 80 dental implants placed in 19 patients. Implants were randomly divided into two groups (n = 40). Seven sessions of LLLT (940 nm diode laser) were scheduled for the test group implants during 2 weeks. Laser was irradiated to the buccal and palatal sides...
October 29, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29068965/single-stage-repair-of-palatal-fistula-and-velopharyngeal-incompetence-by-the-new-l-flap
#16
Mohammad Waheed El-Anwar, Ezzeddin Elsheikh, Sherif Askar
OBJECTIVE: To describe and assess the results of use of the new L-shaped posterior pharyngeal flap for repair of both palatal fistula and velopharyngeal incompetence. METHODS: This study included 10 patients who were diagnosed to have soft palate fistula and persistent velopharyngeal insufficiency (VPI). L-shaped superiorly based pharyngeal flap was harvested from oropharynx and inserted into the soft palate closing the fistula after fistula trimming. The palatal part of the flap (transverse limb) was spread 1 cm horizontally and 1 cm in the anteroposterior direction in soft palate at fistula site closing it without tension...
October 24, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29065047/corticotomy-with-a-palatal-bone-borne-retractor-for-correcting-severe-bimaxillary-protrusion
#17
Min-Ki Noh, Young-Jun Kim, Kyu-Rhim Chung, Seong-Hun Kim, Gerald Nelson
BACKGROUND: This article presents an alternate surgical treatment method to correct a severe anterior protrusion in the adult patient with an extremely thin alveolus. METHODS: In the maxilla, a wide linear corticotomy was performed under local anesthesia. Cortical alveolar bone of the upper first bicuspids area was widely removed. Orthopedic force for bony block movement was applied by a palatal bone-borne type retractor supported by skeletal anchorage. Residual extraction space closure was performed by biocreative orthodontics strategy (BOS)...
October 23, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29062213/antiglide-versus-lateral-plate-fixation-for-danis-weber-type-b-malleolar-fractures-caused-by-supination-external-rotation-injury
#18
Miroslav Kilian, Peter Csörgö, Silvia Vajczikova, Jan Luha, Radoslav Zamborsky
PURPOSE: The purpose of this study was to evaluate functional results and the frequency of complications in the distal fibula Danis-Weber type B fractures caused by supination-external rotation injury in a group of lateral and antiglide plate fixation. METHODS: This prospective study evaluated 44 patients with a minimum of one-year follow-up. Patients were divided into two groups: one lateral plate group (24 patients) and group with an antiglide plate (20 patients)...
October 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29059666/-interdisciplinary-surgical-and-prosthetic-treatment-of-adenocarcinoma-of-the-palate
#19
Piotr Chomiuk, Jolanta E Loster, Katarzyna Uliasz-Jawor, Paweł Stręk
INTRODUCTION: The palatal mucosa requires careful testing prior to prosthetic treatment. Pathological changes may occur during the period of use of a dental prosthetic, especially when worn constantly. Aim of the report: We describe the case of a patient who experienced extensive changes in the mucosa of the hard palate over 12 years of dentures used. CASE PRESENTATION: The 78-year-old female patient was referred to the Department of Otolaryngology of the Jagiellonian University Hospital in Krakow with a diagnosis of adenocarcinoma of the palate...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29053389/mrpl53-a-new-candidate-gene-for-orofacial-clefting-identified-using-an-eqtl-approach
#20
C Masotti, L A Brito, A C Nica, K U Ludwig, K Nunes, C P Savastano, C Malcher, S G Ferreira, G S Kobayashi, D F Bueno, N Alonso, D Franco, A Rojas-Martinez, S E Dos Santos, P A Galante, D Meyer, T Hünemeier, E Mangold, E T Dermitzakis, M R Passos-Bueno
A valuable approach to understand how individual and population genetic differences can predispose to disease is to assess the impact of genetic variants on cellular functions (e.g., gene expression) of cell and tissue types related to pathological states. To understand the genetic basis of nonsyndromic cleft lip with or without cleft palate (NSCL/P) susceptibility, a complex and highly prevalent congenital malformation, we searched for genetic variants with a regulatory role in a disease-related tissue, the lip muscle (orbicularis oris muscle [OOM]), of affected individuals...
October 1, 2017: Journal of Dental Research
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