Huazhen Xu, Xiuli Lu, Mei Li, Xiaodan Huang, Nan Yao, Haining Gan, Xuejun Huang, Ziming Zhao, Zixuan Hu, Xinxin Zhao, Yijing Lai, Minyi Li, Shilong Chen, Yuxing Chen, Dane Huang
BACKGROUND: The discovering of an osteoclast (OC) coupling active agent, capable of suppressing OC-mediated bone resorption while concurrently stimulating osteoblast (OB)-mediated bone formation, presents a promising strategy to overcome limitations associated with existing antiresorptive agents. However, there is a lack of research on active OC coupling agents. PURPOSE: This study aims to investigate the potential of Jiangu Formula (JGF) in inhibiting OCs while maintaining the OCOB coupling function...
February 28, 2024: Phytomedicine