keyword
https://read.qxmd.com/read/38488044/moderate-intensity-combined-training-induces-lipidomic-changes-in-individuals-with-obesity-and-type-2-diabetes
#21
JOURNAL ARTICLE
Renata Garbellini Duft, Ivan Luiz Padilha Bonfante, Susana Alejandra Palma-Duran, Mara Patrícia Traina Chacon-Mikahil, Julian Leether Griffin, Cláudia Regina Cavaglieri
CONTEXT: Alterations in the lipid metabolism are linked to metabolic disorders such as insulin resistance (IR), obesity and type 2 diabetes (T2D). Regular exercise, particularly combined training (CT), is a well-known non-pharmacological treatment that combines aerobic (AT) and resistance (RT) training benefits. However, it is unclear whether moderate-intensity exercise without dietary intervention induces changes in lipid metabolism to promote a 'healthy lipidome'. OBJECTIVE: The study aimed to investigate the effect of 16 weeks of CT on plasma and white adipose tissue in both sexes, middle-aged subjects with normal weight, obesity and T2D using an ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) untargeted lipidomics approach...
March 15, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38483321/who-s-haywood-path-to-leadership-i-am-no-jackie-robinson
#22
JOURNAL ARTICLE
Haywood L Brown
Having been afforded many opportunities throughout my academic career, I took on the challenges that chronicled my path to leadership. In many instances, I was the first person of color to enter that educational and leadership environment. I am grateful to many mentors who have guided and supported me over the 4 decades since the time of my residency through fellowships and the various institutions to which I have been affiliated. It continues to be a great journey, making a contribution to the Ob Gyn academic community and advocating for quality and equitable women's health care...
March 14, 2024: Clinical Obstetrics and Gynecology
https://read.qxmd.com/read/38482856/management-of-hypoactive-sexual-desire-dysfunction-at-a-specialized-service-in-women-s-sexual-health
#23
JOURNAL ARTICLE
Bruna Holanda Luz do Nascimento, Juliana Ribeiro Figueira, Ana Carolina Japur de Sá Rosa-E-Silva, Rosana Maria Reis, Maíra Cristina Ribeiro Andrade, Luiz Gustavo Oliveira Brito, Lucia Alves da Silva Lara
Hypoactive sexual desire dysfunction (HSDD) is prevalent among women. This retrospective cohort study aimed to verify the results of the strategies used by Gynecologists and Obstetricians (Ob-gyn) residents in the management of female HSDD. For this, we conducted a data collection of patient medical records of women with HSDD from the Human Sexuality Studies outpatient clinic of the Human Reproduction Center, Department of Gynecology and Obstetrics of FMRP-USP, from 2005 to 2019. Among the 437 women included, 361 (82...
March 14, 2024: Journal of Sex & Marital Therapy
https://read.qxmd.com/read/38477240/-choice-of-hybrid-interventions-for-iliac-femoral-arterial-lesions
#24
JOURNAL ARTICLE
G B Fataliev, V S Arakelyan, A A Shubin
OBJECTIVE: To compare the short-term and long-term outcomes of hybrid interventions after various infrainguinal reconstructions (restoration of blood flow through superficial femoral artery and pulsatile blood flow through deep femoral artery) in patients with iliac-femoral arterial disease. MATERIAL AND METHODS: A retrospective analysis included patients after hybrid iliac-femoral interventions between 2014 and 2018. These interventions included stenting of iliac arteries and various open infrainguinal reconstructions...
2024: Khirurgiia
https://read.qxmd.com/read/38474779/effect-of-tempeh-and-daidzein-on-calcium-status-calcium-transporters-and-bone-metabolism-biomarkers-in-ovariectomized-rats
#25
JOURNAL ARTICLE
Iskandar Azmy Harahap, Maciej Kuligowski, Adam Cieslak, Paweł A Kołodziejski, Joanna Suliburska
Menopause marks a critical life stage characterized by hormonal changes that significantly impact bone health, leading to a heightened susceptibility to bone fractures. This research seeks to elucidate the impact of daidzein and tempeh on calcium status, calcium transporters, and bone metabolism in an ovariectomized rat model. Forty female Wistar rats, aged 3 months, participated in a two-phase experiment. The initial phase involved inducing a calcium deficit, while the second phase comprised dietary interventions across five groups: Sham (S) and Ovariectomy (O) with a standard diet, O with bisphosphonate (OB), O with pure daidzein (OD), and O with tempeh (OT)...
February 26, 2024: Nutrients
https://read.qxmd.com/read/38471598/traditional-multilocus-phylogeny-fails-to-fully-resolve-palearctic-ground-squirrels-spermophilus-relationships-but-reveals-a-new-species-endemic-to-west-siberia
#26
JOURNAL ARTICLE
Evgeniy Simonov, Natalia V Lopatina, Sergey V Titov, Anastasiya D Ivanova, Oleg V Brandler, Vadim L Surin, Vera A Matrosova, Alisa E Dvilis, Nataliya V Oreshkova, Svetlana Yu Kapustina, Fedor N Golenishchev, Oleg A Ermakov
Previous efforts to reconstruct evolutionary history of Palearctic ground squirrels within the genus Spermophilus have primarily relied on a single mitochondrial marker for phylogenetic data. In this study, we present the first phylogeny with comprehensive taxon sampling of Spermophilus via a conventional multilocus approach utilizing five mitochondrial and five nuclear markers. Through application of the multispecies coalescent model, we constructed a species tree revealing four distinct clades that diverged during the Late Miocene...
March 10, 2024: Molecular Phylogenetics and Evolution
https://read.qxmd.com/read/38471318/jiangu-formula-a-novel-osteoclast-osteoblast-coupling-agent-for-effective-osteoporosis-treatment
#27
JOURNAL ARTICLE
Huazhen Xu, Xiuli Lu, Mei Li, Xiaodan Huang, Nan Yao, Haining Gan, Xuejun Huang, Ziming Zhao, Zixuan Hu, Xinxin Zhao, Yijing Lai, Minyi Li, Shilong Chen, Yuxing Chen, Dane Huang
BACKGROUND: The discovering of an osteoclast (OC) coupling active agent, capable of suppressing OC-mediated bone resorption while concurrently stimulating osteoblast (OB)-mediated bone formation, presents a promising strategy to overcome limitations associated with existing antiresorptive agents. However, there is a lack of research on active OC coupling agents. PURPOSE: This study aims to investigate the potential of Jiangu Formula (JGF) in inhibiting OCs while maintaining the OCOB coupling function...
February 28, 2024: Phytomedicine
https://read.qxmd.com/read/38468186/the-olfactory-bulb-a-neuroendocrine-spotlight-on-feeding-and-metabolism
#28
REVIEW
Romana Stark
Olfaction is the most ancient sense and is needed for food-seeking, danger protection, mating and survival. It is often the first sensory modality to perceive changes in the external environment, before sight, taste or sound. Odour molecules activate olfactory sensory neurons that reside on the olfactory epithelium in the nasal cavity, which transmits this odour-specific information to the olfactory bulb (OB), where it is relayed to higher brain regions involved in olfactory perception and behaviour. Besides odour processing, recent studies suggest that the OB extends its function into the regulation of food intake and energy balance...
March 11, 2024: Journal of Neuroendocrinology
https://read.qxmd.com/read/38467350/bibliometric-analysis-of-the-global-trends-in-immune-related-recurrent-pregnancy-loss-research-over-the-last-two-decades
#29
JOURNAL ARTICLE
Jing-Wei Li, Honglin Xv, Ren-Tao Wan
PROBLEM: A comprehensive analysis was conducted to explore the scientific output on immune-related recurrent pregnancy loss (RPL) and its key aspects. Despite the lack of clear explanations for most RPL cases, immune factors were found to play a significant role. METHOD OF STUDY: The study utilized a bibliometric approach, searching the Web of Science Core Collection database for relevant literature published between 2004 and 2023. RESULTS: The collected dataset consisted of 2228 articles and reviews, revealing a consistent increase in publications and citations over the past two decades...
March 11, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38460755/metabolic-state-modulates-neural-processing-of-odors-in-the-human-olfactory-bulb
#30
JOURNAL ARTICLE
Behzad Iravani, Johannes Frasnelli, Artin Arshamian, Johan N Lundström
The olfactory and endocrine systems have recently been shown to reciprocally shape the homeostatic processes of energy intake. As demonstrated in animal models, the individual's metabolic state dynamically modulates how the olfactory bulb process odor stimuli using a range of endocrine signals. Here we aimed to determine whether the neural processing of odors in human olfactory bulb is modulated by metabolic state. Participants were exposed to food-associated odors, in separate sessions being hungry and sated, while neural responses from the olfactory bulb was obtained using electrobulbogram...
March 7, 2024: Biological Psychology
https://read.qxmd.com/read/38459487/obstetrics-and-gynecology-applicant-perceptions-of-residency-program-culture-with-virtual-interviews-a-qualitative-analysis-of-social-media-posts
#31
JOURNAL ARTICLE
Laura H Jacques, Elise S Cowley, Shanaya M Hebgen, Ryan J Spencer, Corinne M Hale
BACKGROUND: In the United States, Obstetrics and Gynecology residency interviews are instrumental in assessing the compatibility between medical student applicants and residency programs during the match process. Applicant perceptions of Obstetrics and Gynecology residency culture are a key component in determining how they rank residency programs. In 2020, residency interviews transitioned to a virtual format, and little is known about how applicants evaluated program culture during this first round of universal virtual interviews...
March 8, 2024: BMC Medical Education
https://read.qxmd.com/read/38458480/tangshen-formula-alleviates-inflammatory-injury-against-aged-diabetic-kidney-disease-through-modulating-gut-microbiota-composition-and-related-amino-acid-metabolism
#32
JOURNAL ARTICLE
Dan-Qian Chen, Hao-Jun Zhang, Wen Zhang, Kai Feng, Hui Liu, Hai-Ling Zhao, Ping Li
Diabetic kidney disease (DKD) is leading causes and one of the fastest growing causes of chronic kidney disease worldwide, and leads to high morbidity and mortality. Emerging evidences have revealed gut microbiota dysbiosis and related metabolism dysfunction play a dominant role in DKD progression and treatment through modulating inflammation. Our previous studies showed that Tangshen Formula (TSF), a Chinese herbal prescription, exhibited anti-inflammatory effect on DKD, but underlying mechanism that involved gut microbiota and related metabolism in aged model remained obscure...
March 9, 2024: Experimental Gerontology
https://read.qxmd.com/read/38457691/synthesis-of-raspberry-like-nanoparticles-via-surface-grafting-of-positively-charged-polyelectrolyte-brushes-colloidal-stability-and-surface-properties
#33
JOURNAL ARTICLE
Bashayer Saad Aldakkan, Nikolaos Chalmpes, Genggeng Qi, Mohamed Amen Hammami, Mazen Yousef Kanj, Emmanuel P Giannelis
A method to synthesize stable, raspberry-like nanoparticles (NPs), using surface grafting of poly(glycidyl methacrylate) (PGMA) brushes on a polystyrene (PS) core with varying grafting densities, is reported. A two-step functionalization reaction of PGMA epoxide groups comprising an amination step first using ethylene diamine and then followed by a quaternization using glycidyltrimethylammonium chloride generates permanently and positively charged polyelectrolyte brushes, which result in both steric and electrostatic stabilization...
March 8, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38457022/viscoelasticity-of-a-carbon-nanotube-laden-air-water-interface
#34
JOURNAL ARTICLE
Shing-Yun Chang, Sahil R Vora, Charles D Young, Abhishek Shetty, Anson W K Ma
The viscoelasticity of a carbon nanotube (CNT)-laden air-water interface was characterized using two different experimental methods. The first experimental method used a Langmuir-Pockels (LP) trough coupled with a pair of oscillating barriers. The second method is termed the Bicone-Trough (BT) method, where a LP trough was custom-built and fit onto a rheometer equipped with a bicone fixture to standardize the preparation and conditioning of a particle-laden interface especially at high particle coverages. The performance of both methods was evaluated by performing Fast Fourier Transform (FFT) analysis to calculate the signal-to-noise ratios (SNR)...
March 8, 2024: European Physical Journal. E, Soft Matter
https://read.qxmd.com/read/38456001/automatic-segmentation-of-skeletal-muscles-from-mr-images-using-modified-u-net-and-a-novel-data-augmentation-approach
#35
JOURNAL ARTICLE
Zhicheng Lin, William H Henson, Lisa Dowling, Jennifer Walsh, Enrico Dall'Ara, Lingzhong Guo
Rapid and accurate muscle segmentation is essential for the diagnosis and monitoring of many musculoskeletal diseases. As gold standard, manual annotation suffers from intensive labor and high inter-operator reproducibility errors. In this study, deep learning (DL) based automatic muscle segmentation from MR scans is investigated for post-menopausal women, who normally experience a decline in muscle volume. The performance of four Deep Learning (DL) models was evaluated: U-Net and UNet++ and two modified U-Net networks, which combined feature fusion and attention mechanisms (Feature-Fusion-UNet, FFU, and Attention-Feature-Fusion-UNet, AFFU)...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38451721/assessing-knowledge-counseling-and-referral-patterns-regarding-fertility-preservation-before-gonadotoxic-treatments-among-physicians-in-the-military-health-system
#36
JOURNAL ARTICLE
David Boedeker, Kiley Hunkler, Carissa Pekny, Nora Watson, Meghan Yamasaki, Sara Drayer, Trimble Spitzer
Purpose: We sought to evaluate physicians' baseline knowledge of fertility preservation services available to patients with a cancer diagnosis within the military health system (MHS). Methods: Data on current cancer prevalence of over 31,000 unique cancer diagnoses were obtained from a comprehensive nationwide MHS dataset. Additionally, a 22-item survey was distributed to physicians practicing within the MHS assessing knowledge of reproductive health benefits, oncofertility counseling practices, and subspecialist referral patterns...
March 6, 2024: Journal of Adolescent and Young Adult Oncology
https://read.qxmd.com/read/38450466/-objective-functional-monitoring-of-retinoprotective-treatment-in-diabetic-retinopathy
#37
JOURNAL ARTICLE
A I Malakhova, V V Strakhov, Y D Kovaleva, Y A Malakhova
UNLABELLED: In recent years, there has been a growing interest in the contribution of neuroretinal degeneration to the pathogenesis of diabetic retinopathy (DR). PURPOSE: This study assesses the effect of the drug Retinalamin on the functional state of the retina in patients with DR using the Diopsys NOVA Vision Testing System that utilizes electrophysiological (EP) technology. MATERIAL AND METHODS: The study included patients with type 1 and 2 diabetes mellitus (DM) with DR of any stage without macular edema...
2024: Vestnik Oftalmologii
https://read.qxmd.com/read/38446270/parent-intention-to-participate-in-an-online-intervention-to-enhance-health-behavior-change-among-youth-treated-with-psychotropic-medication-who-are-overweight-or-obese-an-application-of-the-theory-of-planned-behavior
#38
JOURNAL ARTICLE
Kathryn A Richardson, Elizabeth L A Punke, Barbara S Dabrowski, Abby L Teply, Johnathan Walker, Christine L McKibbin
Youth with mental health disorders (MHD), particularly those who take psychotropic medications, are at increased risk of being overweight or obese (OW/OB) when compared to typical youth. Parents are important resources for interventions addressing OW/OB. However, parents of youth with MHD may face challenges that require interventions designed to address their needs. Prior to investing research funding in the development of interventions for this group, research is needed to understand factors associated with parents' decisions to enroll in these programs...
March 6, 2024: J Prev (2022)
https://read.qxmd.com/read/38444317/efficacy-of-semaglutide-in-overweight-and-obese-patients-with-type-1-diabetes
#39
JOURNAL ARTICLE
Satish K Garg, Gurleen Kaur, Zehra Haider, Erika Rodriquez, Christie Beatson, Janet Snell-Bergeon
Introduction: More than two-thirds of patients with type 1 diabetes (T1D) are overweight (OW) and/or obese (OB) in the USA and Western Europe, resulting in insulin resistance as in type 2 diabetes. None of the currently available glucagon like polypeptide 1 (GLP-1) analogs are approved for patients with T1D. A higher dose of semaglutide has been approved by the Food and Drug Administration (FDA) for subjects with body mass index (BMI) >27 kg/m2 . We evaluated the real-world use of semaglutide in patients with T1D...
March 2024: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/38442503/baroreflex-afferent-function-is-a-part-of-insights-of-leptin-mediated-blood-pressure-reduction-and-leptin-resistance-hypertension
#40
JOURNAL ARTICLE
Shi-Gang Ren, Dong-Mei Li, Hua Liu
The aim of this study is to verify the impact of Leptin in blood pressure (BP) regulation and Leptin-resistance in metabolic/neurogenic hypertension through baroreflex afferents and dysregulation. Artery BP/heart rate (HR) were measured while nodose (NG) microinjection of Leptin, membrane depolarization/inward current were obtained by whole-cell patch from NG neurons isolated from adult female rats. Baroreflex sensitivity (BRS) tested with PE/SNP, distribution/expression of Leptin/receptors in the NG/nucleus tractus solitary (NTS) examined using immumostaining and qRT-PCR, and serum concentrations of Leptin/NE measured by ELISA were observed in control and high fructose-drinking induced hypertension (HTN-HFD) rats...
February 29, 2024: Neuropeptides
keyword
keyword
6637
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.