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non-invasive ventilation and ards

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https://www.readbyqxmd.com/read/27903208/early-experience-of-a-new-extracorporeal-carbon-dioxide-removal-device-for-acute-hypercapnic-respiratory-failure
#1
Ravindranath Tiruvoipati, Hergen Buscher, James Winearls, Jeff Breeding, Debasish Ghosh, Shimonti Chaterjee, Gary Braun, Eldho Paul, John F Fraser, John Botha
BACKGROUND: Recent advances in the technology of extracorporeal respiratory assist systems have led to a renewed interest in extracorporeal carbon dioxide removal (ECCOR). The Hemolung is a new, low-flow, venovenous, minimally invasive, partial ECCOR device that has recently been introduced to clinical practice to aid in avoiding invasive ventilation or to facilitate lung-protective ventilation. OBJECTIVE: We report our early experience on use, efficacy and safety of the Hemolung in three Australian intensive care units...
December 2016: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/27889372/-non-invasive-ventilation-in-children-do-we-need-more-evidence
#2
G Mortamet, G Emeriaud, P Jouvet, B Fauroux, S Essouri
Respiratory failure is the leading cause of hospital admissions in the pediatric intensive care unit (PICU) and is associated with significant morbidity and mortality. Mechanical ventilation, preferentially delivered by a non-invasive route (NIV), is currently the first-line treatment for respiratory failure since it is associated with a reduction in the intubation rate. This ventilatory support is increasingly used in the PICU, but its wider use contrasts with the paucity of studies in this field. This review aims to describe the main indications of NIV in acute settings: (i) bronchiolitis; (ii) postextubation respiratory failure; (iii) acute respiratory distress syndrome; (iv) pneumonia; (v) status asthmaticus; (vi) acute chest syndrome; (vii) left heart failure; (viii) exacerbation of chronic respiratory failure; (ix) upper airway obstruction and (x) end-of-life care...
November 23, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27761453/non-invasive-ventilation-in-acute-respiratory-distress-syndrome-helmet-use-saves-lives
#3
COMMENT
Inderpaul Singh Sehgal, Ritesh Agarwal
No abstract text is available yet for this article.
September 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27761452/a-new-horizon-for-the-use-of-non-invasive-ventilation-in-patients-with-acute-respiratory-distress-syndrome
#4
COMMENT
Michele Carron
Non-invasive ventilation (NIV) has assumed an important role in the management of acute respiratory failure (ARF). NIV, compared with standard medical therapy, improves survival and reduces complications in selected patients with ARF. NIV represents the first-line intervention for some forms of ARF, such as chronic obstructive pulmonary disease (COPD) exacerbations and acute cardiogenic pulmonary edema. The use of NIV is also well supported for immunocompromised patients who are at high risk for infectious complications from endotracheal intubation...
September 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27757516/potentially-modifiable-factors-contributing-to-outcome-from-acute-respiratory-distress-syndrome-the-lung-safe-study
#5
John G Laffey, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, Ednan K Bajwa, Laurent Brochard, Kevin Clarkson, Andres Esteban, Luciano Gattinoni, Frank van Haren, Leo M Heunks, Kiyoyasu Kurahashi, Jon Henrik Laake, Anders Larsson, Daniel F McAuley, Lia McNamee, Nicolas Nin, Haibo Qiu, Marco Ranieri, Gordon D Rubenfeld, B Taylor Thompson, Hermann Wrigge, Arthur S Slutsky, Antonio Pesenti
PURPOSE: To improve the outcome of the acute respiratory distress syndrome (ARDS), one needs to identify potentially modifiable factors associated with mortality. METHODS: The large observational study to understand the global impact of severe acute respiratory failure (LUNG SAFE) was an international, multicenter, prospective cohort study of patients with severe respiratory failure, conducted in the winter of 2014 in a convenience sample of 459 ICUs from 50 countries across five continents...
October 18, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27753501/non-invasive-ventilation-of-patients-with-ards-insights-from-the-lung-safe-study
#6
Giacomo Bellani, John G Laffey, Tài Pham, Fabiana Madotto, Eddy Fan, Laurent Brochard, Andres Esteban, Luciano Gattinoni, Vesna Bumbasirevic, Lise Piquilloud, Frank van Haren, Anders Larsson, Daniel F McAuley, Philippe R Bauer, Yaseen M Arabi, Marco Ranieri, Massimo Antonelli, Gordon D Rubenfeld, B Taylor Thompson, Hermann Wrigge, Arthur S Slutsky, Antonio Pesenti
BACKGROUND: Non-invasive ventilation (NIV) is increasingly used in patients with Acute Respiratory Distress Syndrome (ARDS). Whether, during NIV, the categorization of ARDS severity based on the PaO2/FiO2 Berlin criteria is useful is unknown. The evidence supporting NIV use in patients with ARDS remains relatively sparse. METHODS: The Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study described the management of patients with ARDS...
October 18, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27730283/apnoeic-oxygenation-via-high-flow-nasal-cannula-oxygen-combined-with-non-invasive-ventilation-preoxygenation-for-intubation-in-hypoxaemic-patients-in-the-intensive-care-unit-the-single-centre-blinded-randomised-controlled-optiniv-trial
#7
Samir Jaber, Marion Monnin, Mehdi Girard, Matthieu Conseil, Moussa Cisse, Julie Carr, Martin Mahul, Jean Marc Delay, Fouad Belafia, Gérald Chanques, Nicolas Molinari, Audrey De Jong
PURPOSE: High-flow nasal cannula oxygen (HFNC) has the potential to provide apnoeic oxygenation. We decided to assess in a proof-of-concept study whether the addition of HFNC to non-invasive ventilation (NIV) could reduce oxygen desaturation during intubation, compared with NIV alone for preoxygenation, in severely hypoxaemic intensive care unit (ICU) patients with respiratory failure. METHODS: We conducted a randomised, controlled, single-centre trial with assessor-blinded outcome assessment in patients admitted to the ICU...
October 11, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27473068/integrin-%C3%AE-d%C3%AE-2-cd11d-cd18-mediates-experimental-malaria-associated-acute-respiratory-distress-syndrome-ma-ards
#8
Isaclaudia G de Azevedo-Quintanilha, Adriana Vieira-de-Abreu, André Costa Ferreira, Daniele O Nascimento, Alessandra M Siqueira, Robert A Campbell, Tatiana P Teixeira Ferreira, Tatiana M Gutierrez, Gabriel M Ribeiro, Patricia M R E Silva, Alysson R Carvalho, Patricia T Bozza, Guy A Zimmerman, Hugo C Castro-Faria-Neto
BACKGROUND: Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a potentially lethal complication of clinical malaria. Acute lung injury in MA-ARDS shares features with ARDS triggered by other causes, including alveolar inflammation and increased alveolar-capillary permeability, leading to leak of protein-rich pulmonary oedema fluid. Mechanisms and physiologic alterations in MA-ARDS can be examined in murine models of this syndrome. Integrin αDβ2 is a member of the leukocyte, or β2 (CD18), sub-family of integrins, and emerging observations indicate that it has important activities in leukocyte adhesion, accumulation and signalling...
2016: Malaria Journal
https://www.readbyqxmd.com/read/27393077/cardiovascular-emergencies-and-cardiac-arrest-in-a-pregnant-woman
#9
Anne-Sophie Ducloy-Bouthors, Max Gonzalez-Estevez, Benjamin Constans, Alexandre Turbelin, Catherine Barre-Drouard
No abstract text is available yet for this article.
July 5, 2016: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/27387451/acute-respiratory-distress-syndrome-after-aspiration-of-lamp-oil-in-a-fire-eater-a-case-report
#10
Nico Behnke, Jekaterina Breitkreuz, Cordula Buck, Marc Hinterthaner, Alexander Emmert
BACKGROUND: Fire-eater's pneumonia is an exogenous chemical pneumonitis after accidental aspiration of hydrocarbon fluids during the act of fire-eating. There have been few case reports in the literature regarding complications after fire-eating but so far none, to the best of our knowledge, have described such drastic and life-threatening pulmonary complications as in this case while only having swallowed a small amount of fluid. CASE PRESENTATION: We present a case of fire-eater's pneumonia in a 28-year-old white man with severe pulmonary complications...
2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27373812/non-invasive-ventilation-by-helmet-more-effective-than-face-mask-in-acute-respiratory-distress-syndrome
#11
Hilary Marshall
No abstract text is available yet for this article.
August 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27340744/the-use-of-life-saving-extracorporeal-membrane-oxygenation-ecmo-for-pregnant-woman-with-status-asthmaticus
#12
Carolin Steinack, Renato Lenherr, Heidy Hendra, Daniel Franzen
INTRODUCTION: Status asthmaticus can develop into a life-threatening disorder that requires mechanical ventilation. Severe respiratory failure during pregnancy can worsen maternal and fetal outcomes. Previous case studies have demonstrated extracorporeal membrane oxygenation (ECMO) as a life-saving measure for pregnant women with acute respiratory distress syndrome (ARDS) as well as non-pregnant patients with status asthmaticus. CASE STUDY: A 25-year-old woman, who was 5 weeks pregnant, was admitted with status asthmaticus and severe hypercapnic respiratory failure...
June 24, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27272916/kinetic-therapy-in-multiple-trauma-patients-with-severe-thoracic-trauma-a-treatment-option-to-reduce-ventilator-time-and-improve-outcome
#13
S Wutzler, K Sturm, T Lustenberger, H Wyen, K Zacharowksi, I Marzi, T Bingold
PURPOSE: Continuous lateral rotational therapy (CLRT) has been described as a promising approach for prophylaxis and treatment of respiratory complications in critically ill patients over two decades ago. However, meta-analyses failed to demonstrate any significant benefit on outcome by CLRT, possibly due to the heterogeneity and low overall quality of available studies. METHODS: Observational trial over a 3-year period on outcome in trauma patients (Injury Severity Score, ISS ≥16) with severe thoracic injury (Abbreviated Injury Scale, AISThorax ≥3) initially treated with CLRT as standard of care...
June 6, 2016: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/27198165/effectiveness-of-inspiratory-termination-synchrony-with-automatic-cycling-during-noninvasive-pressure-support-ventilation
#14
Yuqing Chen, Kewen Cheng, Xin Zhou
BACKGROUND Pressure support ventilation (PSV) is a standard method for non-invasive home ventilation. A bench study was designed to compare the effectiveness of patient-ventilator inspiratory termination synchronization with automated and conventional triggering in various respiratory mechanics models. MATERIAL AND METHODS Two ventilators, the Respironics V60 and Curative Flexo ST 30, connected to a Hans Rudolph Series 1101 lung simulator, were evaluated using settings that simulate lung mechanics in patients with chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), or normal lungs...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27121623/what-s-next-after-ards-long-term-outcomes
#15
REVIEW
Davide Chiumello, Silvia Coppola, Sara Froio, Miriam Gotti
ARDS is a life-threatening organ failure due to several pulmonary and extrapulmonary injuries with an incidence between 5 and 60 cases/100,000 persons/y. Patients with ARDS have non-cardiogenic pulmonary edema and dyspnea often requiring invasive mechanical ventilation and intensive care admission. Although the short-term mortality rate has significantly decreased in the last decade, mainly due to the widespread application of lung-protective ventilation and better general support, long-term outcomes are still unsatisfactory...
May 2016: Respiratory Care
https://www.readbyqxmd.com/read/26966115/cut-off-point-for-switching-from-non-invasive-ventilation-to-intubation-in-severe-ards-fifty-shades-of-grey
#16
LETTER
Luc Quintin
No abstract text is available yet for this article.
2016: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/26966114/cut-off-point-for-switching-from-non-invasive-ventilation-to-intubation-in-severe-ards-still-a-spectrum-of-greys-and-whites
#17
LETTER
Szymon Skoczyński, Antonio M Esquinas
No abstract text is available yet for this article.
2016: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/26364264/impaired-respiratory-function-and-heightened-pulmonary-inflammation-in-episodic-binge-ethanol-intoxication-and-burn-injury
#18
Jill A Shults, Brenda J Curtis, Michael M Chen, Eileen B O'Halloran, Luis Ramirez, Elizabeth J Kovacs
Clinical data indicate that cutaneous burn injuries covering greater than 10% of the total body surface area are associated with significant morbidity and mortality, in which pulmonary complications, including acute respiratory distress syndrome (ARDS), contribute to nearly half of all patient deaths. Approximately 50% of burn patients are intoxicated at the time of hospital admission, which increases days on ventilators by 3-fold, and doubles the length of hospitalization, compared to non-intoxicated burn patients...
November 2015: Alcohol
https://www.readbyqxmd.com/read/26329352/preventive-nebulization-of-mucolytic-agents-and-bronchodilating-drugs-in-invasively-ventilated-intensive-care-unit-patients-nebulae-study-protocol-for-a-randomized-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
Sophia M van der Hoeven, Jan M Binnekade, Corianne A J M de Borgie, Frank H Bosch, Henrik Endeman, Janneke Horn, Nicole P Juffermans, Nardo J M van der Meer, Maruschka P Merkus, Hazra S Moeniralam, Bart van Silfhout, Mathilde Slabbekoorn, Willemke Stilma, Jan Willem Wijnhoven, Marcus J Schultz, Frederique Paulus
BACKGROUND: Preventive nebulization of mucolytic agents and bronchodilating drugs is a strategy aimed at the prevention of sputum plugging, and therefore atelectasis and pneumonia, in intubated and ventilated intensive care unit (ICU) patients. The present trial aims to compare a strategy using the preventive nebulization of acetylcysteine and salbutamol with nebulization on indication in intubated and ventilated ICU patients. METHODS/DESIGN: The preventive nebulization of mucolytic agents and bronchodilating drugs in invasively ventilated intensive care unit patients (NEBULAE) trial is a national multicenter open-label, two-armed, randomized controlled non-inferiority trial in the Netherlands...
2015: Trials
https://www.readbyqxmd.com/read/26312101/pathophysiological-basis-of-acute-respiratory-failure-on-non-invasive-mechanical-ventilation
#20
C Romero-Dapueto, H Budini, F Cerpa, D Caceres, V Hidalgo, T Gutiérrez, J Keymer, R Pérez, J Molina, C Giugliano-Jaramillo
Noninvasive mechanical ventilation (NIMV) was created for patients who needed noninvasive ventilator support, this procedure decreases the complications associated with the use of endotracheal intubation (ETT). The application of NIMV has acquired major relevance in the last few years in the management of acute respiratory failure (ARF), in patients with hypoxemic and hypercapnic failure. The main advantage of NIMV as compared to invasive mechanical ventilation (IMV) is that it can be used earlier outside intensive care units (ICUs)...
2015: Open Respiratory Medicine Journal
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