keyword
https://read.qxmd.com/read/38492817/airway-stenting-for-liberation-from-positive-pressure-ventilation-in-patients-with-central-airway-obstruction-presenting-with-acute-respiratory-failure
#1
JOURNAL ARTICLE
Bertin D Salguero, Abhinav Agrawal, Viren Kaul, Christian M Lo Cascio, Greta Joy, Matsuo So, Rohit Munagala, Timothy Harkin, Udit Chaddha
BACKGROUND: Central airway obstruction (CAO) can lead to acute respiratory failure (RF) necessitating positive pressure ventilation (PPV). The efficacy of airway stenting to aid liberation from PPV in patients with severe acute RF has been scarcely published. We present a systematic review and our recent experience. METHODS: A systematic review of PubMed was performed, and a retrospective review of cases performed at our two institutions from 2018 to 2022 in adult patients who needed stent insertion for extrinsic or mixed CAO complicated by RF necessitating PPV...
March 14, 2024: Respiratory Medicine
https://read.qxmd.com/read/38490918/neurodevelopmental-outcomes-of-extremely-preterm-infants-with-bronchopulmonary-dysplasia-bpd-a-retrospective-cohort-study
#2
REVIEW
Khoa L Nguyen, Dominic A Fitzgerald, Annabel Webb, Barbara Bajuk, Himanshu Popat
OBJECTIVE: To investigate the neurodevelopmental outcomes for preterm infants born < 29 weeks gestation with/without bronchopulmonary dysplasia (BPD). STUDY DESIGN: Preterm infants < 29 weeks' gestation born 2007-2018 in New South Wales and the Australian Capital Territory, Australia, were included. Infants who died < 36 weeks' postmenstrual age and those with major congenital anomalies were excluded. Subjects were assessed at 18-42 months corrected age using the Bayley Scales of Infant Development, 3rd edition...
March 1, 2024: Paediatric Respiratory Reviews
https://read.qxmd.com/read/38490660/multicentre-randomised-double-blind-placebo-controlled-proof-of-concept-study-of-lsalt-peptide-as-prevention-of-acute-respiratory-distress-syndrome-and-acute-kidney-injury-in-patients-infected-with-sars-cov-2-covid-19
#3
JOURNAL ARTICLE
Ranjani Somayaji, David R Luke, Arthur Lau, Rahmet Guner, Ŏ Fehmi Tabak, Mark Hepokoski, Nancy Gardetto, Steven A Conrad, Sunil D Kumar, Kalyan Ghosh, Stephen M Robbins, Donna L Senger, Daisy Sun, Rachel K S Lim, Jonathan Liu, Fatma Eser, Ridvan Karaali, Alain Tremblay, Daniel Muruve
OBJECTIVE: Dipeptidase-1 (DPEP-1) is a recently discovered leucocyte adhesion receptor for neutrophils and monocytes in the lungs and kidneys and serves as a potential therapeutic target to attenuate inflammation in moderate-to-severe COVID-19. We aimed to evaluate the safety and efficacy of the DPEP-1 inhibitor, LSALT peptide, to prevent specific organ dysfunction in patients hospitalised with COVID-19. DESIGN: Phase 2a randomised, placebo-controlled, double-blinded, trial...
March 15, 2024: BMJ Open
https://read.qxmd.com/read/38488252/temporal-effects-of-caffeine-on-intrapulmonary-shunt-in-preterm-ventilated-infants
#4
JOURNAL ARTICLE
Ourania Kaltsogianni, Ravindra Bhat, Anne Greenough, Theodore Dassios
OBJECTIVES: We hypothesized that caffeine would be associated with a transient reduction in the right-to-left shunt and VA /Q. We aimed to explore the temporal effects of caffeine on right-to-left shunt, ventilation perfusion ratio (VA /Q) and shift of the oxyhaemoglobin dissociation curve (ODC) in premature ventilated infants. METHODS: Retrospective cohort study at a tertiary neonatal unit of infants born at less than 31 weeks of gestation that were mechanically ventilated on day three of life...
March 18, 2024: Journal of Perinatal Medicine
https://read.qxmd.com/read/38487173/effect-of-age-and-icu-types-on-mortality-in-invasive-mechanically-ventilated-patients-with-sepsis-receiving-dexmedetomidine-a-retrospective-cohort-study-with-propensity-score-matching
#5
JOURNAL ARTICLE
Shuai Zhao, Ruihui Zhou, Qi Zhong, Mi Zhang
Background: Dexmedetomidine is recommended for sedation in patients on mechanical ventilation. Whether age or ICU types could alter mortality in invasive mechanically ventilated patients with sepsis receiving dexmedetomidine is unknown. Methods: We included patients with sepsis receiving invasive mechanical ventilation from the Medical Information Mart for Intensive Care IV database. The exposure was intravenous dexmedetomidine administration during ICU stay. The primary outcome was 28-day mortality. The secondary outcomes were the length of ICU stay and liberation from invasive mechanical ventilation...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38486304/impact-of-covid-19-on-posttraumatic-stress-disorder-in-icu-survivors-a-prospective-observational-comparative-cohort-study
#6
JOURNAL ARTICLE
Pierre Kalfon, Wissam El-Hage, Marie-Agnès Geantot, Constance Favier, Laetitia Bodet-Contentin, Khaldoun Kuteifan, Pierre-Yves Olivier, Didier Thévenin, Julien Pottecher, Jullien Crozon-Clauzel, Bénédicte Mauchien, Arnaud Galbois, Roland de Varax, Sabine Valera, Philippe Estagnasie, Audrey Berric, Martine Nyunga, Nathalie Revel, Georges Simon, Benjamin Kowalski, Achille Sossou, Thomas Signouret, Marc Leone, Charles Delalé, Aurélien Seemann, Sigismond Lasocki, Jean-Pierre Quenot, Antoine Monsel, Olivier Michel, Mathieu Page, René-Gilles Patrigeon, Walid Nicola, Arnaud W Thille, Guillaume Hekimian, Pascal Auquier, Karine Baumstarck
BACKGROUND: Posttraumatic stress disorder (PTSD) after a stay in the intensive care unit (ICU) can affect one in five ICU survivors. At the beginning of the coronavirus disease 2019 (COVID-19) pandemic, admission to the ICU for COVID-19 was stressful due to the severity of this disease. This study assessed whether admission to the ICU for COVID-19 was associated with a higher prevalence of PTSD compared with other causes of ICU admission after adjustment for pre-ICU psychological factors...
March 14, 2024: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38484345/predictors-of-mortality-among-hospitalized-hypertensive-patients-with-covid-19-during-third-and-fourth-waves-in-pakistan
#7
JOURNAL ARTICLE
Narendar Kumar, Siti M Sheikh Ghadzi, Pushp L Rajpoot, Hemalatha Thanganadar, Furqan K Hashmi, Ahmed Noor, Ali Qureshi, Shafique Hussain, Syed A Syed Sulaiman
INTRODUCTION: Hypertension significantly contributes to the severity and mortality of COVID-19 patients. It has also been a risk factor for prolonged hospitalization and the need for intensive care. However, the data is still evolving. Therefore, this study investigated the predictors of mortality among hypertensive COVID-19 patients. METHODOLOGY: A single-center cohort study was performed at Indus Hospital and Health Network, Karachi, Pakistan, between April 1, 2021, and October 31, 2021...
February 29, 2024: Journal of Infection in Developing Countries
https://read.qxmd.com/read/38476546/effectiveness-of-high-flow-nasal-cannula-hfnc-versus-bilevel-positive-airway-pressure-bipap-in-preventing-tracheal-reintubation-in-patients-with-high-risk-of-extubation-failure-in-intensive-care-unit-a-randomised-comparative-trial
#8
JOURNAL ARTICLE
Nisha Kumari, Bibha Kumari, Sanjeev Kumar, Nidhi Arun, Ritu Kumari
BACKGROUND AND AIMS: The incidence of tracheal extubation failure in high-risk patients is higher, and non-invasive ventilation is suggested to avoid tracheal reintubation. This study compares the effectiveness of bilevel positive airway pressure (BiPAP) and high flow nasal cannula (HFNC) to reduce the rate of reintubation in intensive care unit (ICU) patients with increased risk of extubation failure. METHODS: This randomised comparative trial was conducted on 60 high-risk patients on mechanical ventilators admitted to the ICU, ready for weaning after a spontaneous breathing trial...
March 2024: Indian Journal of Anaesthesia
https://read.qxmd.com/read/38470068/european-academy-of-neurology-ean-guideline-on-the-management-of-amyotrophic-lateral-sclerosis-in-collaboration-with-european-reference-network-for-neuromuscular-diseases-ern-euro-nmd
#9
JOURNAL ARTICLE
Philip Van Damme, Ammar Al-Chalabi, Peter M Andersen, Adriano Chiò, Philippe Couratier, Mamede De Carvalho, Orla Hardiman, Magdalena Kuźma-Kozakiewicz, Albert Ludolph, Christopher J McDermott, Jesus S Mora, Susanne Petri, Katrin Probyn, Evy Reviers, François Salachas, Vincenzo Silani, Ole-Bjørn Tysnes, Leonard H van den Berg, Gemma Villanueva, Markus Weber
BACKGROUND: This update of the guideline on the management of amyotrophic lateral sclerosis (ALS) was commissioned by the European Academy of Neurology (EAN) and prepared in collaboration with the European Reference Network for Neuromuscular Diseases (ERN EURO-NMD) and the support of the European Network for the Cure ALS (ENCALS) and the European Organization for Professionals and Patients with ALS (EUpALS). METHODS: Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology was used to assess the effectiveness of interventions for ALS...
March 12, 2024: European Journal of Neurology
https://read.qxmd.com/read/38465034/factors-associated-with-failure-of-non-invasive-ventilation-in-preterm-neonates-requiring-initial-respiratory-support
#10
JOURNAL ARTICLE
Abhishek Nath, Sushil Srivastava, Ravi Sachan, Dheeraj Shah
BACKGROUND: Non-invasive ventilation (NIV) modalities minimize the requirement for invasive mechanical ventilation (IMV) in preterm neonates, therefore improving neonatal outcomes, as IMV is linked to increased complications. However, NIV has demonstrated an elevated likelihood of failure, for which various studies have been done, but very little research is available addressing the factors that are responsible for NIV failure in resource-limited areas of developing nations. Understanding the underlying factors and their association with NIV failure in very and moderately preterm neonates at a tertiary care hospital would be important in devising targeted strategies to increase NIV success and newborn outcomes...
February 2024: Curēus
https://read.qxmd.com/read/38463604/analysis-of-therapeutic-effects-on-type-ii-respiratory-failure-and-impact-on-blood-gas-changes-high-flow-nasal-oxygen-therapy-vs-non-invasive-positive-pressure-ventilation
#11
JOURNAL ARTICLE
Yongping Liu, Ning Liu, Ying Li, Lixiu Nie, Lin Li
OBJECTIVE: To evaluate the efficacy of high-flow nasal oxygen therapy (HFNO) vs. non-invasive positive pressure ventilation (NIPPV) in type II respiratory failure, and analyze their impact on blood gas parameters. METHODS: A retrospective analysis of 110 cases of type II respiratory failure treated from April 2021 to March 2023 categorized patients into control (NIPPV, n=50) and observation (HFNO, n=60) groups. Both groups received comprehensive nursing interventions...
2024: American Journal of Translational Research
https://read.qxmd.com/read/38459440/the-role-of-nutrition-in-analysis-of-risk-factors-and-short-term-outcomes-for-late-onset-necrotizing-enterocolitis-among-very-preterm-infants-%C3%A2-a-nationwide-multicenter-study-in-china
#12
MULTICENTER STUDY
Kun-Yao Hong, Yao Zhu, Fan Wu, Jian Mao, Ling Liu, Rong Zhang, Yan-Mei Chang, Wei Shen, Li-Xia Tang, Xiu-Zhen Ye, Yin-Ping Qiu, Li Ma, Rui Cheng, Hui Wu, Dong-Mei Chen, Ling Chen, Ping Xu, Hua Mei, San-Nan Wang, Fa-Lin Xu, Rong Ju, Zhi Zheng, Xiao-Mei Tong, Xin-Zhu Lin
BACKGROUND: Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease, primarily affects preterm newborns and occurs after 7 days of life (late-onset NEC, LO-NEC). Unfortunately, over the past several decades, not much progress has been made in its treatment or prevention. This study aimed to analyze the risk factors for LO-NEC, and the impact of LO-NEC on short-term outcomes in very preterm infants (VPIs) with a focus on nutrition and different onset times. METHOD: Clinical data of VPIs were retrospectively collected from 28 hospitals in seven different regions of China from September 2019 to December 2020...
March 8, 2024: BMC Pediatrics
https://read.qxmd.com/read/38458492/review-of-electrical-impedance-tomography-in-the-pediatric-patient
#13
REVIEW
S Cabezudo Ballesteros, P Sanabria Carretero, F Reinoso Barbero
Electrical impedance tomography (EIT) is a new method of monitoring non-invasive mechanical ventilation, at the bedside and useful in critically ill patients. It allows lung monitoring of ventilation and perfusion, obtaining images that provide information on lung function. It is based on the physical principle of impedanciometry or the body's ability to conduct an electrical current. Various studies have shown its usefulness both in adults and in pediatrics in respiratory distress syndrome, pneumonia and atelectasis in addition to pulmonary thromboembolism and pulmonary hypertension by also providing information on pulmonary perfusion, and may be very useful in perioperative medicine; especially in pediatrics avoiding repetitive imaging tests with ionizing radiation...
March 6, 2024: Revista española de anestesiología y reanimación
https://read.qxmd.com/read/38457009/lung-ultrasound-score-predicts-outcomes-in-patients-with-acute-respiratory-failure-secondary-to-covid-19-treated-with-non-invasive-respiratory-support-a-prospective-cohort-study
#14
JOURNAL ARTICLE
Mauro Castro-Sayat, Nicolás Colaianni-Alfonso, Luigi Vetrugno, Gustavo Olaizola, Cristian Benay, Federico Herrera, Yasmine Saá, Guillermo Montiel, Santiago Haedo, Ignacio Previgliano, Ada Toledo, Catalina Siroti
BACKGROUND: Lung ultrasound has demonstrated its usefulness in several respiratory diseases management. One derived score, the Lung Ultrasound (LUS) score, is considered a good outcome predictor in patients with Acute Respiratory Failure (ARF). Nevertheless, it has not been tested in patients undergoing non-invasive respiratory support (NIRS). Taking this into account, the aim of this study is to evaluate LUS score as a predictor of 90-day mortality, ETI (Endotracheal intubation) and HFNC (High Flow Nasal Cannula) failure in patients with ARF due to COVID-19 admitted to a Respiratory Intermediate Care Unit (RICU) for NIRS management...
March 8, 2024: The ultrasound journal
https://read.qxmd.com/read/38455690/valsalva-manoeuvre-induced-pneumothorax-and-pneumomediastinum-in-a-covid-19-patient-with-ards-an-unusual-mechanism-for-this-complication
#15
JOURNAL ARTICLE
Totawatte Don Srilak Weerawardane, Nils Bürgisser, Amandine Berner, Matteo Coen
BACKGROUND: Until now, only a few cases of Valsalva-induced barotraumas (pneumothorax, pneumomediastinum and subcutaneous emphysema) have been described, and none of them among COVID-19 patients. CASE DESCRIPTION: A man in his 50s was admitted for SARS-CoV-2-related acute respiratory distress syndrome (ARDS). Initial evolution was favourable with non-invasive ventilatory support, high-flow oxygen nasal cannula and the best supportive drugs available at the time...
2024: European Journal of Case Reports in Internal Medicine
https://read.qxmd.com/read/38454954/pulmonary-hypertension-in-an-adult-patient-with-congenital-central-hypoventilation-syndrome-a-case-report
#16
Yosuke Terui, Shoko Ohura, Tetsuji Nozaki, Takuya Yagi
BACKGROUND: Congenital central hypoventilation syndrome (CCHS) is a life-threatening disorder of autonomic respiratory control. Mutations in the paired-like homeobox 2B (PHOX2B) gene impair respiratory drive, causing hypercarbia and hypoxaemia. Most patients with CCHS are diagnosed in the neonatal period; however, a few are diagnosed in adulthood. CASE SUMMARY: We report a 32-year-old man with a history of unexplained cyanosis 14 days after birth. He presented to our hospital with breathlessness and abnormal electrocardiogram findings discovered in a health check-up...
March 2024: European Heart Journal. Case Reports
https://read.qxmd.com/read/38454423/pediatric-sepsis-inflammatory-blood-biomarkers-that-correlate-with-clinical-variables-and-severity-of-illness-scores
#17
JOURNAL ARTICLE
Sean Leonard, Hailey Guertin, Natalya Odoardi, Michael R Miller, Maitray A Patel, Mark Daley, Gediminas Cepinskas, Douglas D Fraser
BACKGROUND: Sepsis is a dysregulated systemic inflammatory response triggered by infection, resulting in organ dysfunction. A major challenge in clinical pediatrics is to identify sepsis early and then quickly intervene to reduce morbidity and mortality. As blood biomarkers hold promise as early sepsis diagnostic tools, we aimed to measure a large number of blood inflammatory biomarkers from pediatric sepsis patients to determine their predictive ability, as well as their correlations with clinical variables and illness severity scores...
March 7, 2024: Journal of Inflammation
https://read.qxmd.com/read/38454348/bioinformatics-analysis-identifies-a-key-gene-hla_dpa1-in-severe-influenza-associated-immune-infiltration
#18
JOURNAL ARTICLE
Liang Chen, Jie Hua, Xiaopu He
BACKGROUND: Severe influenza is a serious global health issue that leads to prolonged hospitalization and mortality on a significant scale. The pathogenesis of this infectious disease is poorly understood. Therefore, this study aimed to identify the key genes associated with severe influenza patients necessitating invasive mechanical ventilation. METHODS: The current study utilized two publicly accessible gene expression profiles (GSE111368 and GSE21802) from the Gene Expression Omnibus database...
March 7, 2024: BMC Genomics
https://read.qxmd.com/read/38454232/comparison-of-the-efficacies-of-high-flow-nasal-cannula-oxygen-therapy-and-non-invasive-nasal-cannula-ventilation-in-preventing-intubation
#19
JOURNAL ARTICLE
Ülkem Koçoğlu Barlas, Abdulrahman Özel, Volkan Tosun, Emine Ufuk Bozkurt, Hasan Serdar Kıhtır
OBJECTIVE: This study aimed to compare high-flow nasal cannula oxygen therapy (nc-HFOT) and non-invasive nasal cannula ventilation (nc-NIV) in terms of intubation requirements. MATERIALS AND METHODS: The study was conducted retrospectively on cases followed up in the pediatric intensive care unit (PICU) between October 2019 and December 2021. RESULTS: Of all cases, 43 (55.8%) were male, and the median age was 16 months. The median PRISM-3 score for all cases was 2...
March 2024: Turkish archives of pediatrics
https://read.qxmd.com/read/38452638/anesthetic-management-of-thyroid-carcinoma-invading-the-upper-tracheal-segment-a-case-report
#20
Yuyan Ding, Lianbing Gu, Lijun Wang, Lingxi Xing, Yihu Zhou, Yueyi Jiang
INTRODUCTION AND IMPORTANCE: Intratracheal tumors account for approximately 0.2 % of respiratory tumors, including primary and secondary tumors. Secondary tumors of the upper trachea are most commonly derived from advanced thyroid cancer. Surgical resection is currently the general curative modality for thyroid cancer with tracheal invasion. Patients with tracheal tumors invading and protruding into the lumen may have reduced oxygen reserve capacity, leading to a shorter safe window for general anesthesia induction...
February 27, 2024: International Journal of Surgery Case Reports
keyword
keyword
66357
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.