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https://www.readbyqxmd.com/read/28822232/this-month-in-ajp
#1
(no author information available yet)
The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology.
August 16, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28821521/effectiveness-of-seasonal-influenza-vaccination-in-patients-with-diabetes-protocol-for-a-nested-case-control-study
#2
Ludovic Casanova, Sébastien Cortaredona, Jean Gaudart, Odile Launay, Philippe Vanhems, Patrick Villani, Pierre Verger
INTRODUCTION: Seasonal influenza vaccination (SIV) is recommended for people with diabetes, but its effectiveness has not been demonstrated. All of the available studies are observational and marred with the healthy vaccine bias, that is, bias resulting from the generally better health behaviours practised by people who choose to be vaccinated against influenza, compared with those who do not. This protocol is intended to study the effectiveness of SIV in people with treated diabetes and simultaneously to control for bias...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821512/protocol-for-an-economic-evaluation-of-the-randomised-controlled-trial-of-culprit-lesion-only-pci-versus-immediate-multivessel-pci-in-acute-myocardial-infarction-complicated-by-cardiogenic-shock-culprit-shock-trial
#3
Zahidul Quayyum, Andrew Briggs, Jose Robles-Zurita, Keith Oldroyd, Uwe Zeymer, Steffen Desch, Suzanne de Waha, Holger Thiele
INTRODUCTION: Emergency percutaneous coronary intervention (PCI) of the culprit lesion for patients with acute myocardial infarctions is an accepted practice. A majority of patients present with multivessel disease with additional relevant stenoses apart from the culprit lesion. In haemodynamically stable patients, there is increasing evidence from randomised trials to support the practice of immediate complete revascularisation. However, in the presence of cardiogenic shock, the optimal management strategy for additional non-culprit lesions is unknown...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821509/does-tai-chi-improve-psychological-well-being-and-quality-of-life-in-patients-with-cardiovascular-disease-and-or-cardiovascular-risk-factors-a-systematic-review-protocol
#4
Guoyan Yang, Wenyuan Li, Huijuan Cao, Nerida Klupp, Jianping Liu, Alan Bensoussan, Hosen Kiat, Dennis Chang
INTRODUCTION: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide. Psychological risk factors such as stress, anxiety and depression are known to play a significant and independent role in the development and progression of CVD and its risk factors. Tai Chi has been reported to be potentially effective for health and well-being. It is of value to assess the effectiveness and safety of Tai Chi on psychological well-being and quality of life in people with CVD and/or cardiovascular risk factors...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28820905/estimating-the-evidential-value-of-significant-results-in-psychological-science
#5
Balazs Aczel, Bence Palfi, Barnabas Szaszi
Quantifying evidence is an inherent aim of empirical science, yet the customary statistical methods in psychology do not communicate the degree to which the collected data serve as evidence for the tested hypothesis. In order to estimate the distribution of the strength of evidence that individual significant results offer in psychology, we calculated Bayes factors (BF) for 287,424 findings of 35,515 articles published in 293 psychological journals between 1985 and 2016. Overall, 55% of all analyzed results were found to provide BF > 10 (often labeled as strong evidence) for the alternative hypothesis, while more than half of the remaining results do not pass the level of BF = 3 (labeled as anecdotal evidence)...
2017: PloS One
https://www.readbyqxmd.com/read/28820754/sleep-apps-what-role-do-they-play-in-clinical-medicine
#6
Christopher P Lorenz, Adrian J Williams
PURPOSE OF REVIEW: Today's smartphones boast more computing power than the Apollo Guidance Computer. Given the ubiquity and popularity of smartphones, are we already carrying around miniaturized sleep labs in our pockets? RECENT FINDINGS: There is still a lack of validation studies for consumer sleep technologies in general and apps for monitoring sleep in particular. To overcome this gap, multidisciplinary teams are needed that focus on feasibility work at the intersection of software engineering, data science and clinical sleep medicine...
August 17, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28820673/asymmetric-compression-of-representational-space-for-object-animacy-categorization-under-degraded-viewing-conditions
#7
Tijl Grootswagers, J Brendan Ritchie, Susan G Wardle, Andrew Heathcote, Thomas A Carlson
Animacy is a robust organizing principle among object category representations in the human brain. Using multivariate pattern analysis methods, it has been shown that distance to the decision boundary of a classifier trained to discriminate neural activation patterns for animate and inanimate objects correlates with observer RTs for the same animacy categorization task [Ritchie, J. B., Tovar, D. A., & Carlson, T. A. Emerging object representations in the visual system predict reaction times for categorization...
August 18, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28820506/physiological-and-ecological-implications-of-an-iron-or-hydrogen-oxidizing-member-of-the-zetaproteobacteria-ghiorsea-bivora-gen-nov-sp-nov
#8
Jiro F Mori, Jarrod J Scott, Kevin W Hager, Craig L Moyer, Kirsten Küsel, David Emerson
Chemosynthetic Fe-oxidizing communities are common at diffuse-flow hydrothermal vents throughout the world's oceans. The foundational members of these communities are the Zetaproteobacteria, a class of Proteobacteria that is primarily associated with ecosystems fueled by ferrous iron, Fe(II). We report here the discovery of two new isolates of Zetaproteobacteria isolated from the Mid-Atlantic Ridge (TAG-1), and the Mariana back-arc (SV-108), that are unique in that they can utilize either Fe(II) or molecular hydrogen (H2) as sole electron donor and oxygen as terminal electron acceptor for growth...
August 18, 2017: ISME Journal
https://www.readbyqxmd.com/read/28820228/use-of-geographical-information-system-data-for-emergency-management-points-of-distribution-analysis-with-pod-locator-2-0
#9
Christopher A Chung
In 2010, the article Location and Analysis of Emergency Management Point of Distributions (PODs) for Hurricane Ike was published in the Journal of Emergency Management. Using a program titled point of distribution locator (POD Locator 1.0), the article reported a 46 percent improvement in positioning PODs over the locations selected by emergency managers during Hurricane Ike in 2008. While the program could produce more effective POD locations for a given situation, a major weakness of the program was the difficulty with which population and location data were manually entered into the program for subsequent analysis...
March 2017: Journal of Emergency Management: JEM
https://www.readbyqxmd.com/read/28819776/tongxinluo-capsule-for-cardiac-syndrome-x-a-systematic-review-and-meta-analysis
#10
Hui-Min Mao, Mi Liu, Hua Qu, Li-Qiong Wang, Da-Zhuo Shi
OBJECTIVE: To evaluate the efficacy and safety of Tongxinluo Capsule (, TXL) for patients with cardiac syndrome X (CSX). METHODS: Randomized controlled trials (RCTs) regarding TXL in the treatment of CSX were searched in Chinese Biomedicine Literature Database, China National Knowledge Infrastructure, Chinese Scientific Journal Database, Wanfang Database, PubMed, EMBASE, Cochrane Central Register of Controlled Trial, websites of the Chinese and International Clinical Trial Registry platform up to June 30, 2015...
August 17, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28819339/depression-after-stroke-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#11
REVIEW
Akin Ojagbemi, Onoja Akpa, Fisayo Elugbadebo, Mayowa Owolabi, Bruce Ovbiagele
OBJECTIVE: We aimed to conduct a systematic review and meta-analysis of prevalence and characteristics of poststroke depression (PSD) in sub-Saharan Africa (SSA). METHODS: We searched Medline, PsycINFO, and African Journals OnLine using keywords for stroke and depression and the .mp. operator for all 54 SSA countries/regions. Further information was retrieved through a manual search of references from relevant published and unpublished articles. We included only peer-reviewed original studies with epidemiological or experimental designs, conducted random-effect meta-analysis, and identified the most commonly associated factors by weight (inverse of variance method)...
2017: Behavioural Neurology
https://www.readbyqxmd.com/read/28819323/excessive-body-fat-linked-to-blunted-somatosensory-cortex-response-to-general-reward-in-adolescents
#12
J F Navas, A Barros-Loscertales, V Costumero-Ramos, J Verdejo-Román, R Vilar-López, A Verdejo-García
BACKGROUND AND AIMS: The brain reward system is key to understanding adolescent obesity in the current obesogenic environment, rich in highly appetising stimuli, to which adolescents are particularly sensitive. We aimed to examine the association between body fat levels and brain reward system responsivity to general (monetary) rewards in male and female adolescents. METHOD: Sixty-eight adolescents (34 females; mean age [standard deviation]=16.56 [1.35]) were measured for body fat levels with bioelectric impedance, and underwent a functional magnetic resonance imaging (fMRI) scan during the Monetary Incentive Delay (MID) task...
August 18, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28819068/rural-emergency-care-360%C3%A2-mobilising-healthcare-professionals-decision-makers-patients-and-citizens-to-improve-rural-emergency-care-in-the-province-of-quebec-canada-a-qualitative-study-protocol
#13
Richard Fleet, Gilles Dupuis, Jean-Paul Fortin, Jocelyn Gravel, Mathieu Ouimet, Julien Poitras, France Légaré
INTRODUCTION: Emergency departments (EDs) are an important safety net for rural populations. Results of our earlier studies suggest that rural Canadian hospitals have limited access to advanced imaging services and intensive care units and that patients are transferred over large distances. They also revealed significant geographical variations in rural services. In the absence of national standards, our studies raise questions about inequities in rural access to emergency services and the risks for citizens...
August 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28819063/stard-for-abstracts-essential-items-for-reporting-diagnostic-accuracy-studies-in-journal-or-conference-abstracts
#14
Jérémie F Cohen, Daniël A Korevaar, Constantine A Gatsonis, Paul P Glasziou, Lotty Hooft, David Moher, Johannes B Reitsma, Henrica Cw de Vet, Patrick M Bossuyt
No abstract text is available yet for this article.
August 17, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28819010/new-insight-on-the-s100a1-stip1-complex-highlights-the-important-relationship-between-allostery-and-entropy-in-protein-function
#15
Nathaniel V Nucci
Calcium signaling serves as a nexus of many vital cellular processes. Of particular importance is the role the calcium signaling plays in the prevention of protein misfolding, and the S100 family of calcium-binding proteins is a key player in this pathway. While the S100 proteins carry out a range of roles, the interaction of S100A1 and the stress-inducible phosphoprotein 1 (STIP1) has been shown to be particularly important. A recent study by Maciejewski et al. in Biochemical Journal (Biochemical Journal (2017) 474, 1853-1866) revealed new insights into the nature of the S100A1-STIP1 interaction...
August 17, 2017: Biochemical Journal
https://www.readbyqxmd.com/read/28818646/best-practice-in-research-consensus-statement-on-ethnopharmacological-field-studies-consefs
#16
REVIEW
Michael Heinrich, Andreas Lardos, Marco Leonti, Caroline Weckerle, Merlin Willcox
BACKGROUND: Ethnopharmacological research aims at gathering information on local and traditional uses of plants and other natural substances. However, the approaches used and the methods employed vary, and while such a variability is desirable in terms of scientific diversity, research must adhere to well defined quality standards and reproducible methods OBJECTIVES: With ConSEFS (the Consensus Statement on Ethnopharmacological Field Studies) we want to define best-practice in developing, conducting and reporting field studies focusing on local and traditional uses of medicinal and food plants, including studies using a historical approach...
August 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28818559/-to-boldly-go-where-no-one-has-gone-before
#17
Keith W Kelley
Americans are suffering from a culture of taking pills. Six out of ten Americans utilize at least one prescription drug, and more than one in ten use five or more prescription medicines. Although this torrent of taking pills is already high, drug use in the USA has not yet crested. Prescription drugs have specific targets, but often they adversely affect other tissues and organs. In keeping with the mission of the recently named National Center for Complementary and Integrative Health (NCCIH), Brain, Behavior, and Immunity searches for the underlying cause and potential efficacy of both drug and non-drug interventions...
August 14, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28818547/contracting-infectious-diseases-in-sub-saharan-african-wetlands-a-question-of-use-a-review
#18
REVIEW
Carmen Anthonj, Andrea Rechenburg, Christoph Höser, Thomas Kistemann
Worldwide the pressure on water is increasing. In parts of Sub-Saharan Africa (SSA), natural wetlands constitute the only accessible water resources, providing water free of charge, agricultural potential and livelihoods in otherwise uninhabitable landscapes, which is why they are being used extensively. The degradation and contamination of water which result from the use of wetlands has the potential to spread disease-causing microorganisms and provide increased breeding habitats for disease vectors, Despite this importance, case studies are lacking and knowledge gaps remain about whether and how different kinds of wetland use influence the exposure to health risks and transmission of infectious diseases...
July 29, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28818281/american-journal-of-preventive-medicine-2016-article-of-the-year
#19
EDITORIAL
Matthew L Boulton
No abstract text is available yet for this article.
September 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28818090/trends-in-maternal-and-neonatal-mortality-in-south-africa-a-systematic-review-protocol
#20
Damian J Damian, Bernard Njau, Ester Lisasi, Sia E Msuya, Andrew Boulle
BACKGROUND: Measuring and monitoring progress towards Millennium Development Goals (MDG) 4 and 5 requires valid and reliable estimates of maternal and neonatal mortality. In South Africa, there are conflicting reports on the estimates of maternal and neonatal mortality, derived from both direct and indirect estimation techniques. This study aims to systematically review the estimates made of maternal and neonatal mortality in the period from 1990 to 2015 in South Africa and determine trends over this period...
August 17, 2017: Systematic Reviews
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