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https://www.readbyqxmd.com/read/29691868/de-implementation-a-concept-analysis
#1
Michele J Upvall, Annette M Bourgault
AIM: The purpose of this concept analysis is to explore the meaning of de-implementation and provide a definition that can be used by researchers and clinicians to facilitate evidence-based practice. BACKGROUND: De-implementation is a relatively unknown process overshadowed by the novelty of introducing new ideas and techniques into practice. Few studies have addressed the challenge of de-implementation and the cognitive processes involved when terminating harmful or unnecessary practices...
April 25, 2018: Nursing Forum
https://www.readbyqxmd.com/read/29691864/foxo1-transcriptional-activities-in-vegf-expression-and-beyond-a-key-regulator-in-functional-angiogenesis
#2
Bin Ren
FoxO1 has emerged as an important regulator of angiogenesis. Recent work published in this Journal shows that FoxO1 regulates VEGF expression in keratinocytes and is required for angiogenesis in wound healing. Since FoxO1 also regulates CD36 transcription, and endothelial cell differentiation and vascular maturation, this transcription factor may be essential for the formation of functional vascular networks via coupling the regulation of CD36 in vascular endothelial cells under physiological and pathological conditions...
April 24, 2018: Journal of Pathology
https://www.readbyqxmd.com/read/29691650/first-unitary-then-divided-the-temporal-dynamics-of-dividing-attention
#3
Lisa N Jefferies, Joseph B Witt
Whether focused visual attention can be divided has been the topic of much investigation, and there is a compelling body of evidence showing that, at least under certain conditions, attention can be divided and deployed as two independent foci. Three experiments were conducted to examine whether attention can be deployed in divided form from the outset, or whether it is first deployed as a unitary focus before being divided. To test this, we adapted the methodology of Jefferies, Enns, and Di Lollo (Journal of Experimental Psychology: Human Perception and Performance 40: 465, 2014), who used a dual-stream Attentional Blink paradigm and two letter-pair targets...
April 24, 2018: Psychological Research
https://www.readbyqxmd.com/read/29691250/long-term-neuroprotective-effect-of-erythropoietin-on-executive-functions-in-very-preterm-children-epokids-protocol-of-a-prospective-follow-up-study
#4
Flavia Maria Wehrle, Ulrike Held, Ruth Tuura O'Gorman, Vera Disselhoff, Barbara Schnider, Jean-Claude Fauchère, Petra Hüppi, Beatrice Latal, Cornelia Franziska Hagmann
INTRODUCTION: Premature infants are particularly vulnerable to brain injuries with associated cognitive and behavioural deficits. The worldwide first randomised interventional multicentre trial investigating the neuroprotective effects of erythropoietin (entitled 'Does erythropoietin improve outcome in very preterm infants?' (NCT00413946)) included 450 very preterm infants in Switzerland. MRI at term equivalent age showed less white matter (WM) injury in the erythropoietin group compared with the placebo group...
April 24, 2018: BMJ Open
https://www.readbyqxmd.com/read/29691248/understanding-influences-on-the-uptake-of-pulmonary-rehabilitation-in-the-east-of-england-an-inclusive-design-mixed-methods-study-protocol
#5
Yuanyuan Liu, Terry Dickerson, Frances Early, Jonathan Fuld, P John Clarkson
INTRODUCTION: 1.2 million people in the UK have chronic obstructive pulmonary disease (COPD) that causes breathlessness, difficulty with daily activities, infections and hospitalisation. Pulmonary rehabilitation (PR), a programme of supervised exercise and education, is recommended for patients with COPD. However, only 1 in 10 of those who need it receive PR. Also, the UK National COPD Audit Programme concluded that the COPD treatment might not be accessible to people with disabilities...
April 24, 2018: BMJ Open
https://www.readbyqxmd.com/read/29691246/effectiveness-of-implementing-a-best-practice-primary-healthcare-model-for-low-back-pain-betterback-compared-with-current-routine-care-in-the-swedish-context-an-internal-pilot-study-informed-protocol-for-an-effectiveness-implementation-hybrid-type-2-trial
#6
Allan Abbott, Karin Schröder, Paul Enthoven, Per Nilsen, Birgitta Öberg
INTRODUCTION: Low back pain (LBP) is a major health problem commonly requiring healthcare. In Sweden, there is a call from healthcare practitioners (HCPs) for the development, implementation and evaluation of a best practice primary healthcare model for LBP. AIMS: (1) To improve and understand the mechanisms underlying changes in HCP confidence, attitudes and beliefs for providing best practice coherent primary healthcare for patients with LBP; (2) to improve and understand the mechanisms underlying illness beliefs, self-care enablement, pain, disability and quality of life in patients with LBP; and (3) to evaluate a multifaceted and sustained implementation strategy and the cost-effectiveness of the BetterBack☺ model of care (MOC) for LBP from the perspective of the Swedish primary healthcare context...
April 24, 2018: BMJ Open
https://www.readbyqxmd.com/read/29690893/inclusion-and-definition-of-acute-renal-dysfunction-in-critically-ill-patients-in-randomized-controlled-trials-a-systematic-review
#7
Rogerio da Hora Passos, Joao Gabriel Rosa Ramos, André Gobatto, Juliana Caldas, Etienne Macedo, Paulo Benigno Batista
BACKGROUND: In evidence-based medicine, multicenter, prospective, randomized controlled trials (RCTs) are the gold standard for evaluating treatment benefits and ensuring the effectiveness of interventions. Patient-centered outcomes, such as mortality, are most often the preferred evaluated outcomes. While there is currently agreement on how to classify renal dysfunction in critically ill patients , the application frequency of this new classification system in RCTs has not previously been evaluated...
April 24, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29689721/reaction-of-amyloid-%C3%AE-peptide-antibody-with-different-infectious-agents-involved-in-alzheimer-s-disease
#8
Aristo Vojdani, Elroy Vojdani, Evan Saidara, Datis Kharrazian
As early as the 1980s, molecular virologist Ruth Itzhaki began to investigate if there was a causal connection between infections and neurodegenerative disorder. Although the theory has yet to be universally embraced, in 2016 Itzhaki and 33 other scientists from all over the world published a review article in this very journal presenting evidence for the causal role of pathogens in Alzheimer's disease (AD). Exactly how and in what way pathogens affect the induction of AD has yet to be determined, but one possible answer may involve the cross-reactivity of different pathogens with amyloid-β (Aβ)...
April 14, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29689612/nicc-journal-app
#9
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Nursing in Critical Care
https://www.readbyqxmd.com/read/29689127/concept-analysis-and-the-advance-of-nursing-knowledge-state-of-the-science
#10
Beth L Rodgers, Cynthia S Jacelon, Kathleen A Knafl
PURPOSE: Despite an overwhelming increase in the number of concept analyses published since the early 1970s, there are significant limitations to the impact of this work in promoting progress in nursing science. DESIGN: We conducted an extensive review of concept analyses published between 1972 and 2017 to identify patterns in analysis and followed this with exploration of an exemplar related to the concept of normalization to demonstrate the capabilities of analysis for promoting concept development and progress...
April 24, 2018: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/29689118/correction-a-prophylactic-multivalent-vaccine-against-different-filovirus-species-is-immunogenic-and-provides-protection-from-lethal-infections-with-ebolavirus-and-marburgvirus-species-in-non-human-primates
#11
Benoit Callendret, Jort Vellinga, Kerstin Wunderlich, Ariane Rodriguez, Robin Steigerwald, Ulrike Dirmeier, Cedric Cheminay, Ariane Volkmann, Trevor Brasel, Ricardo Carrion, Luis D Giavedoni, Jean L Patterson, Chad E Mire, Thomas W Geisbert, Jay W Hooper, Mo Weijtens, Jutta Hartkoorn-Pasma, Jerome Custers, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn
[This corrects the article DOI: 10.1371/journal.pone.0192312.].
2018: PloS One
https://www.readbyqxmd.com/read/29689115/correction-mouse-igg2c-fc-loop-residues-promote-greater-receptor-binding-affinity-than-mouse-igg2b-or-human-igg1
#12
(no author information available yet)
[This corrects the article DOI: 10.1371/journal.pone.0192123.].
2018: PloS One
https://www.readbyqxmd.com/read/29689114/correction-local-thoracic-therapy-improve-prognosis-for-stage-iv-non-small-cell-lung-cancer-patients-combined-with-chemotherapy-a-surveillance-epidemiology-and-end-results-database-analysis
#13
Kaitai Liu, Dawei Zheng, GuoDong Xu, Zhennan Du, Shibo Wu
[This corrects the article DOI: 10.1371/journal.pone.0187350.].
2018: PloS One
https://www.readbyqxmd.com/read/29689106/correction-controversy-matters-impacts-of-topic-and-solution-controversy-on-the-perceived-credibility-of-a-scientist-who-advocates
#14
Lindsey Beall, Teresa A Myers, John E Kotcher, Emily K Vraga, Edward W Maibach
[This corrects the article DOI: 10.1371/journal.pone.0187511.].
2018: PloS One
https://www.readbyqxmd.com/read/29689104/correction-design-and-selection-of-a-camelid-single-chain-antibody-yeast-two-hybrid-library-produced-de-novo-for-the-cap-protein-of-porcine-circovirus-type-2-pcv2
#15
(no author information available yet)
[This corrects the article DOI: 10.1371/journal.pone.0056222.].
2018: PloS One
https://www.readbyqxmd.com/read/29689103/correction-sinking-towards-destiny-high-throughput-measurement-of-phytoplankton-sinking-rates-through-time-resolved-fluorescence-plate-spectroscopy
#16
Catherine C Bannon, Douglas A Campbell
[This corrects the article DOI: 10.1371/journal.pone.0185166.].
2018: PloS One
https://www.readbyqxmd.com/read/29689102/correction-pilates-training-improves-5-km-run-performance-by-changing-metabolic-cost-and-muscle-activity-in-trained-runners
#17
Paula Finatto, Edson Soares Da Silva, Alexandre B Okamura, Bruna P Almada, Jorge L L Storniolo, Henrique B Oliveira, Leonardo A Peyré-Tartaruga
[This corrects the article DOI: 10.1371/journal.pone.0194057.].
2018: PloS One
https://www.readbyqxmd.com/read/29689101/correction-hostile-intruder-toxoplasma-holds-host-organelles-captive
#18
Isabelle Coppens, Julia D Romano
[This corrects the article DOI: 10.1371/journal.ppat.1006893.].
April 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29689095/correction-acral-melanoma-detection-using-a-convolutional-neural-network-for-dermoscopy-images
#19
Chanki Yu, Sejung Yang, Wonoh Kim, Jinwoong Jung, Kee-Yang Chung, Sang Wook Lee, Byungho Oh
[This corrects the article DOI: 10.1371/journal.pone.0193321.].
2018: PloS One
https://www.readbyqxmd.com/read/29689041/-alzheimer-s-disease-an-actual-planetary-health-emergency
#20
Domenico Ribatti
Alzheimer's disease is one of the biggest challenges for anyone involved in research in this area, because unfortunately there is little evidence that one of the various forms of therapy offered has some beneficial and lasting effect. Approximately 1,200 annual publications in scientific journals on this disease have still failed to provide a homogenous picture of the disease, its causes, and its evolution. For these reasons, Alzheimer's disease can be considered as a planetary health emergency of our time.
April 2018: Recenti Progressi in Medicina
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