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Medication errors

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https://www.readbyqxmd.com/read/29792347/fewer-adverse-effects-associated-with-a-modified-two-bag-intravenous-acetylcysteine-protocol-compared-to-traditional-three-bag-regimen-in-paracetamol-overdose
#1
Lars E Schmidt, Ditlev N Rasmussen, Tonny S Petersen, Ines M Macias-Perez, Leo Pavliv, Byron Kaelin, Richard C Dart, Kim Dalhoff
CONTEXT: The intravenous (IV) N-acetylcysteine (NAC) regimen used worldwide in paracetamol overdose is complex with three separate weight-based doses and is associated with a high incidence of adverse events including non-allergic anaphylactoid reactions (NAARs). In 2012, Denmark adopted the two-bag IV NAC regimen which combined the first two infusions of the three-bag regimen and kept the third infusion unchanged. We compared the safety and efficacy of the two-bag IV NAC regimen with the traditional Danish three-bag regimen...
May 24, 2018: Clinical Toxicology
https://www.readbyqxmd.com/read/29792257/a-critique-of-the-shannon-weaver-theory-of-communication-and-its-implications-for-nursing
#2
Debra J Gillespie, Rachel Schiffman
With the Joint Commission's revelation that as much as 65%-70% of the time miscommunication has been discovered to be the root cause of many sentinel events, it may be time to examine a communication theory to support practice improvement efforts. Effective communication has been shown to decrease medical errors, improve patient satisfaction, and increase adherence to treatment plans leading to better health outcomes; yet very few studies have examined communication theories and their applicability to practice...
May 1, 2018: Research and Theory for Nursing Practice
https://www.readbyqxmd.com/read/29792208/automated-chest-screening-based-on-a-hybrid-model-of-transfer-learning-and-convolutional-sparse-denoising-autoencoder
#3
Changmiao Wang, Ahmed Elazab, Fucang Jia, Jianhuang Wu, Qingmao Hu
OBJECTIVE: In this paper, we aim to investigate the effect of computer-aided triage system, which is implemented for the health checkup of lung lesions involving tens of thousands of chest X-rays (CXRs) that are required for diagnosis. Therefore, high accuracy of diagnosis by an automated system can reduce the radiologist's workload on scrutinizing the medical images. METHOD: We present a deep learning model in order to efficiently detect abnormal levels or identify normal levels during mass chest screening so as to obtain the probability confidence of the CXRs...
May 23, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29788936/association-between-stress-fracture-incidence-and-predicted-body-fat-in-united-states-army-basic-combat-training-recruits
#4
Joseph J Knapik, Marilyn A Sharp, Scott J Montain
BACKGROUND: A stress fracture (SF) is a highly debilitating injury commonly experienced in United States Army Basic Combat Training (BCT). Body fat (BF) may be associated with this injury but previous investigations (in athletes) have largely used SF self-reports and lacked sufficient statistical power. This investigation developed an equation to estimate %BF and used that equation to examine the relationship between %BF and SF risk in BCT recruits. METHODS: Data for the %BF predictive equation involved 349 recruits with BF obtained from dual-energy X-ray absorptiometry...
May 22, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29788309/rethinking-the-outpatient-medication-list-increasing-patient-activation-and-education-while-architecting-for-centralization-and-improved-medication-reconciliation
#5
Frank Pandolfe, Adam Wright, Warner V Slack, Charles Safran
Objective: Identify barriers impacting the time consuming and error fraught process of medication reconciliation. Design and implement an electronic medication management system where patient and trusted healthcare proxies can participate in establishing and maintaining an inclusive and up-to-date list of medications. Methods: A patient-facing electronic medication manager was deployed within an existing research project focused on elder care management funded by the AHRQ, InfoSAGE, allowing patients and patients' proxies the ability to build and maintain an accurate and up-to-date medication list...
May 17, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29786598/-hypertrophic-cardiomyopathy-an-intraoperative-death-case-analysis-and-substantiation-of-the-standards-of-perioperative-anesthetic-management-in-a-non-cardiosurgery-clinic
#6
Roman N Fedosiuk, Liliia O Shchupachynska
The article is based on the case analysis of a sudden and unexpected intraoperative death of a 51-year-old female patient with hypertrophic cardiomyopathy, who was undergoing a non-cardiac operation in a non-cardiosurgery clinic, from acute precipitation of left ventricular outflow tract obstruction provoked by surgery and anesthesia. It emphasizes the importance of raising non-cardiac anesthesiologists' awareness of the issue and having clear standards of pre-operative evaluation and perioperative management of patients with hypertrophic cardiomyopathy in order to avoid fatal medical errors...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786019/measuring-situation-awareness-in-medical-education-objective-structured-clinical-examination-guides
#7
Margaret Frere, John Tepper, Markus Fischer, Kieran Kennedy, Thomas Kropmans
Background: Medical errors are among the most prevalent and serious adverse events in health care. Lack of situation awareness (SA) is an important factor leading to such errors. SA can be understood using Endsley's three-tier model: level 1 is perception, level 2 is comprehension, and level 3 is projection. While there is extensive literature on the theory of SA, it is difficult to measure and quantify. The purpose of this pilot study was to measure, identify, and characterize SA in some medical objective structured clinical examination (OSCE) guides, including a 1st year National University of Ireland, Galway (NUIG) OSCE...
September 2017: Education for Health: Change in Training & Practice
https://www.readbyqxmd.com/read/29784754/pediatric-adhd-medication-exposures-reported-to-us-poison-control-centers
#8
Samantha A King, Marcel J Casavant, Henry A Spiller, Nichole L Hodges, Thitphalak Chounthirath, Gary A Smith
: media-1vid110.1542/5754332180001PEDS-VA_2017-3872 Video Abstract OBJECTIVES: To describe the characteristics and trends of exposures to attention-deficit/hyperactivity disorder (ADHD) medications among individuals 0 to 19 years old reported to US poison control centers. METHODS: National Poison Data System data from 2000 through 2014 were retrospectively analyzed to examine pediatric ADHD medication exposures. RESULTS: From 2000 through 2014, there were 156 365 exposures reported to US poison control centers related to ADHD medications...
May 21, 2018: Pediatrics
https://www.readbyqxmd.com/read/29784634/evaluation-of-app-based-serious-gaming-as-a-training-method-in-teaching-chest-tube-insertion-to-medical-students-randomized-controlled-trial
#9
Patrick Haubruck, Felix Nickel, Julian Ober, Tilman Walker, Christian Bergdolt, Mirco Friedrich, Beat Peter Müller-Stich, Franziska Forchheim, Christian Fischer, Gerhard Schmidmaier, Michael C Tanner
BACKGROUND: The insertion of a chest tube should be as quick and accurate as possible to maximize the benefit and minimize possible complications for the patient. Therefore, comprehensive training and assessment before an emergency situation are essential for proficiency in chest tube insertion. Serious games have become more prevalent in surgical training because they enable students to study and train a procedure independently, and errors made have no effect on patients. However, up-to-date evidence regarding the effect of serious games on performance in procedures in emergency medicine remains scarce...
May 21, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29784155/parental-knowledge-of-pediatric-eye-health-in-an-ophthalmology-clinic-setting-validation-and-delivery-of-the-eyee-questionnaire
#10
Natalia Fong, Bethany Easterbrook, Forough Farrokhyar, Kourosh Sabri
OBJECTIVE: We aimed to develop and assess the reliability of a questionnaire assessing parental knowledge on core topics in pediatric eye health. METHODS: In Phase I, the Evaluate Your Eye Education Questionnaire (EYEE-Q) was developed and distributed to ascertain face validity (n = 20). In Phase II, participants completed EYEE-Q twice to determine test-retest reliability (n = 40). In Phase III, EYEE-Q was administered to parents in a tertiary level pediatric ophthalmology clinic to assess knowledge (n = 193)...
June 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29783231/allergenic-weed-pollen-forecast-under-the-mathematical-modeling-method-implementation-in-ukraine
#11
Irina I Motruk, Michael Yu Antomonov, Victoria V Rodinkova, Olena E Aleksandrova, Oleh V Yermishev
OBJECTIVE: Introduction: Allergies are the most common reason of the chronic diseases in developed countries and represent an important medical, social and economic issue, the relevance of which is growing both in these countries and in Ukraine. The most famous of these allergens group is the pollen of ambrosia and pollen of poaceae, which are ubiquitously distributed in the subtropical and temperate climate. The aim: The objective of our study was to develop the mathematical models, which will be able to indicate the probability of the pollen circulation, and thus these models can simplify the forecast of symptoms risk and improve the prophylaxis of pollinosis...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782615/feasibility-study-applying-a-parametric-model-as-the-design-generator-for-3d-printed-orthosis-for-fracture-immobilization
#12
Jianyou Li, Hiroya Tanaka
Background: Applying 3D printing technology for the fabrication of custom-made orthoses provides significant advantages, including increased ventilation and lighter weights. Currently, the design of such orthoses is most often performed in the CAD environment, but creating the orthosis model is a time-consuming process that requires significant CAD experience. This skill gap limits clinicians from applying this technology in fracture treatment. The purpose of this study is to develop a parametric model as the design generator for 3D-printed orthoses for an inexperienced CAD user and to evaluate its feasibility and ease of use via a training and design exercise...
2018: 3D printing in medicine
https://www.readbyqxmd.com/read/29780976/modeling-individual-cyclic-variation-in-human-behavior
#13
Emma Pierson, Tim Althoff, Jure Leskovec
Cycles are fundamental to human health and behavior. Examples include mood cycles, circadian rhythms, and the menstrual cycle. However, modeling cycles in time series data is challenging because in most cases the cycles are not labeled or directly observed and need to be inferred from multidimensional measurements taken over time. Here, we present Cyclic Hidden Markov Models (CyH-MMs) for detecting and modeling cycles in a collection of multidimensional heterogeneous time series data. In contrast to previous cycle modeling methods, CyHMMs deal with a number of challenges encountered in modeling real-world cycles: they can model multivariate data with both discrete and continuous dimensions; they explicitly model and are robust to missing data; and they can share information across individuals to accommodate variation both within and between individual time series...
April 2018: Proceedings of the International World-Wide Web Conference
https://www.readbyqxmd.com/read/29779911/piloting-medication-histories-in-a-pediatric-postanesthesia-care-unit
#14
Nathan Lake, Humaira Nawer, Deborah Wagner
PURPOSE: Develop a medication history process for pediatric postanesthesia care unit (PACU) patients to identify discrepancies between home and inpatient medications and prevent medication errors. DESIGN: Pilot an evidence-based practice change to perform PACU medication histories. METHODS: Inpatients or surgical admissions to general care units at a pediatric tertiary care 348-bed hospital ages 2-18 years were included. Parents/guardians were asked about their child's prescription and over-the-counter medications, allergies, and adherence...
May 18, 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29779162/beyond-social-desirability-bias-investigating-inconsistencies-in-self-reported-hiv-testing-and-treatment-behaviors-among-hiv-positive-adults-in-north-west-province-south-africa
#15
Alyssa C Mooney, Chadwick K Campbell, Mary-Jane Ratlhagana, Jessica S Grignon, Sipho Mazibuko, Emily Agnew, Hailey Gilmore, Scott Barnhart, Adrian Puren, Starley B Shade, Teri Liegler, Sheri A Lippman
This mixed-methods study used qualitative interviews to explore discrepancies between self-reported HIV care and treatment-related behaviors and the presence of antiretroviral medications (ARVs) in a population-based survey in South Africa. ARV analytes were identified among 18% of those reporting HIV-negative status and 18% of those reporting not being on ART. Among participants reporting diagnosis over a year prior, 19% reported multiple HIV tests in the past year. Qualitative results indicated that participant misunderstandings about their care and treatment played a substantial role in reporting inaccuracies...
May 19, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29777986/predicting-of-the-refractive-index-of-haemoglobin-using-the-hybrid-ga-svr-approach
#16
Tajudeen A Oyehan, Ibrahim O Alade, Aliyu Bagudu, Kazeem O Sulaiman, Sunday O Olatunji, Tawfik A Saleh
The optical properties of blood play crucial roles in medical diagnostics and treatment, and in the design of new medical devices. Haemoglobin is a vital constituent of the blood whose optical properties affect all of the optical properties of human blood. The refractive index of haemoglobin has been reported to strongly depend on its concentration which is a function of the physiology of biological cells. This makes the refractive index of haemoglobin an essential non-invasive bio-marker of diseases. Unfortunately, the complexity of blood tissue makes it challenging to experimentally measure the refractive index of haemoglobin...
April 30, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29772057/a-4d-global-respiratory-motion-model-of-the-thorax-based-on-ct-images-a-proof-of-concept
#17
H Fayad, M Gilles, T Pan, D Visvikis
PURPOSE: Respiratory motion reduces the sensitivity and specificity of medical images especially in the thoracic and abdominal areas. It may affect applications such as cancer diagnostic imaging and/or radiation therapy (RT). Solutions to this issue include modelling of the respiratory motion in order to optimize both diagnostic and therapeutic protocols. Personalised motion modeling required patient specific four dimensional (4D) imaging which in the case of 4D computed tomography (4D CT) acquisition is associated with an increased dose...
May 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/29771884/-exophthalmometry-with-computed-tomography
#18
M B Gushchina, D S Afanasyeva, S A Borzenok
Bone abnormalities of orbit seen in patients with trauma or radiolesion are accompanied by enophthalmos or exophthalmos. Conventional measurements of eyeball protrusion with Hertel's exophthalmometer or with computed tomography do not provide accurate and reliable data, especially in patients with asymmetry of lateral orbital rims. PURPOSE: To develop a method of computed exophthalmometry that provides accurate and reliable measurements in patients with various orbital conditions. MATERIAL AND METHODS: Medical records and computerized axial tomography scans of 25 patients' orbits without false enophthalmos or exophthalmos were analyzed posthoc...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29771042/-alarming-system-in-real-time-and-high-quality-display-using-volumerendering-for-otologic-surgical-navigation-a-preclinical-study
#19
W Y Zhang, G D Feng, S Q Chen, Q W Huang, Z Q Gao
Objective: The aim of this study is to design and develop a novel navigation framework that alarms the surgeon with sound during drilling and dynamically renders the high quality medical image data. Method: The accuracy of the proposed system were measured with a skull model using paired point registration and the target registration error (TRE) was computed. We segmented the accurate structure of target and compute the minimum distance between the drill tip and the target. Once the drill tip approached the target structures, the system would alarm the surgeon...
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29770644/comparative-efficacy-of-the-new-optical-biometer-on-intraocular-lens-power-calculation-al-scan-versus-iolmaster
#20
Ahnul Ha, Won Ryang Wee, Mee Kum Kim
PURPOSE: To evaluate the agreement in axial length (AL), keratometry, and anterior chamber depth measurements between AL-Scan and IOLMaster biometers and to compare the efficacy of the AL-Scan on intraocular lens (IOL) power calculations and refractive outcomes with those obtained by the IOLMaster. METHODS: Medical records of 48 eyes from 48 patients who underwent uneventful phacoemulsification and IOL insertion were retrospectively reviewed. One of the two types of monofocal aspheric IOLs were implanted (Tecnis ZCB00 [Tecnis, n = 34] or CT Asphina 509M [Asphina, n = 14])...
May 15, 2018: Korean Journal of Ophthalmology: KJO
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