Faris Durmo, Jimmy Lätt, Anna Rydelius, Silke Engelholm, Sara Kinhult, Krister Askaner, Elisabet Englund, Johan Bengzon, Markus Nilsson, Isabella M Björkman-Burtscher, Thomas Chenevert, Linda Knutsson, Pia C Sundgren
The aim was to evaluate volume, diffusion, and perfusion metrics for better presurgical differentiation between high-grade gliomas (HGG), low-grade gliomas (LGG), and metastases (MET). For this retrospective study, 43 patients with histologically verified intracranial HGG (n = 18), LGG (n = 10), and MET (n = 15) were chosen. Preoperative magnetic resonance data included pre- and post-gadolinium contrast-enhanced T1-weighted fluid-attenuated inversion recover, cerebral blood flow (CBF), cerebral blood volume (CBV), fractional anisotropy, and apparent diffusion coefficient maps used for quantification of magnetic resonance biometrics by manual delineation of regions of interest...
March 2018: Tomography: a Journal for Imaging Research