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https://www.readbyqxmd.com/read/29147805/can-clinical-practice-indicator-relating-to-long-acting-benzodiazepine-use-in-the-elderly-be-easily-generated-in-a-hospital-setting
#1
Badria Kadri, Antonio Teixeira, Christelle Duteil, Annabelle Tan, Hélène Barreteau, Christophe Segouin, Pénélope Troude
BACKGROUND: To improve the appropriate use of long-acting benzodiazepine (la.bzd) prescriptions in the elderly, the Haute Autorité de Santé (HAS) has developed clinical practice indicators (CPI). The alert indicator (AI) evaluates the prevalence of la.bzd prescription among older people. The mastering indicator (MI) corresponds to the prevalence of elderly with a justified, i.e., appropriate, la.bzd prescription among all the elderly with la.bzd prescriptions. OBJECTIVE: The objective of this study was to test the feasibility of routine generation of CPI regarding la...
November 16, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29146489/exploring-the-barriers-to-and-facilitators-of-using-evidence-based-drugs-in-the-secondary-prevention-of-cardiovascular-diseases-findings-from-a-multistakeholder-qualitative-analysis
#2
Victoria Miller, Lavanya Nambiar, Malvika Saxena, Darryl Leong, Amitava Banerjee, José Pablo Werba, Jose Rocha Faria Neto, Katherine Curi Quinto, Mohammed Moniruzzaman, Shweta Khandelwal
BACKGROUND: Health-system barriers and facilitators associated with cardiovascular medication adherence have seldom been studied, particularly in low- and middle-income countries where uptake rates are poorest. OBJECTIVES: This study sought to explore the major obstacles and facilitators to the use of evidence-supported medications for secondary prevention of cardiovascular disease using qualitative analysis in 2 diverse countries across multiple levels of their health care systems...
November 13, 2017: Global Heart
https://www.readbyqxmd.com/read/29145935/effectiveness-of-pharmacist-led-anticoagulation-management-on-clinical-outcomes-a-systematic-review-and-meta-analysis
#3
Kelu Hou, Hui Yang, Zhikang Ye, Ying Wang, Lihong Liu, Xiangli Cui
OBJECTIVES: We performed this systematic review and meta-analysis to confirm whether patients benefit more from pharmacist-led anticoagulation management than other models. METHODS: We searched PubMed, Embase, Cochrane Library and reference lists of yielded results conducted up to April 25, 2017. RCTs and observational cohort studies and case-control studies which compared the percentage of time within the target therapeutic range (TTR), the percentage of time within the expanded therapeutic range (TER), haemorrhage events, thrombosis events, mortality, patient satisfaction and/or medicine cost saving of pharmacist-led anticoagulation management with other models, and species were limited to humans...
2017: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29144250/case-not-closed-prescription-errors-12-years-after-computerized-physician-order-entry-implementation
#4
Gili Kadmon, Michal Pinchover, Avichai Weissbach, Shirley Kogan Hazan, Elhanan Nahum
OBJECTIVE: To assess the prolonged impact of computerized physician order entry (CPOE) on medication prescription errors in pediatric intensive care patients. STUDY DESIGN: This observational study was conducted at a pediatric intensive care unit in which a CPOE (Metavision, iMDsoft, Israel) with a limited clinical decision support system was implemented between 2004 and 2007. Since then, no changes were made to the systems. We analyzed 2500 electronic prescriptions (1250 prescriptions from 2015 and 1250 prescriptions from 2016)...
November 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29143347/validation-of-a-tool-for-reporting-pharmacists-interventions-in-everyday-community-pharmacy
#5
T H Vo, J-D Bardet, B Charpiat, C Leyrissoux, J Gravoulet, B Allenet, O Conort, P Bedouch
WHAT IS KNOWN AND OBJECTIVE: The French Society of Clinical Pharmacy (SFPC) asked a group of experts to adapt the SFPC hospital pharmacists' interventions reporting tool for use in community pharmacy practice. This study aimed to develop and validate a tool for the routine reporting of pharmacists' interventions in French community settings. METHODS: Two groups of community pharmacists coded reports of 60 typical pharmacists' interventions. One group was "experts" (n = 4) who had participated in the development of the tool (internal validation) and the other were "external" community pharmacists (n = 6), naïve to the tool (external validation)...
November 15, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29140819/positive-and-negative-impacts-of-a-continuing-professional-development-intervention-on-pharmacist-practice-a-balanced-measure-evaluation
#6
Sukhjinder Sidhu, Sean K Gorman, Richard S Slavik, Tasha Ramsey, Nicole Bruchet, Sarah Murray
INTRODUCTION: Evaluations of behavior change interventions aimed at improving professional practice are increasingly focused on impacts at the practice and patient outcome levels. Many of these evaluations assume that if the intended changes occur, the result represents an improvement. However, given the systemic nature of clinical practice, a change in one area can produce changes in other areas as well, some of which may adversely affect the patient. Balancing measures are used to determine whether unintended consequences of an intervention have been introduced into other areas of the system...
November 14, 2017: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/29138153/deprescribing-antihyperglycemic-agents-in-older-persons-evidence-based-clinical-practice-guideline
#7
Barbara Farrell, Cody Black, Wade Thompson, Lisa McCarthy, Carlos Rojas-Fernandez, Heather Lochnan, Salima Shamji, Ross Upshur, Manon Bouchard, Vivian Welch
OBJECTIVE: To develop an evidence-based guideline to help clinicians make decisions about when and how to safely taper, stop, or switch antihyperglycemic agents in older adults. METHODS: We focused on the highest level of evidence available and sought input from primary care professionals in guideline development, review, and endorsement processes. Seven clinicians (2 family physicians, 3 pharmacists, 1 nurse practitioner, and 1 endocrinologist) and a methodologist comprised the overall team; members disclosed conflicts of interest...
November 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29134488/impact-of-clinical-pharmacists-intervention-on-management-of-hyperglycemia-in%C3%A2-pregnancy-in-jordan
#8
Razan Adnan Batta, Violet Kasabri, Amal Akour, Dana Hyassat, Abla Albsoul-Younes
Background and objective Hyperglycemia in pregnancy is a risk factor for cardiovascular disease and postpartum (PP) diabetes. This study aimed to assess the impact of the clinical pharmacist-assisted program (CPAP) of optimizing drug therapy and intensive education on main management outcome measures of patient knowledge about diabetes, Quality of life (QoL) as measured by SF-36 including maternal complications, fasting plasma glucose (FPG) control, and HbA1c. Method This is a randomized controlled study. Pregnant (20-28 weeks) patients with hyperglycemia received CPAP (n = 51) as compared with conventional management (n = 34)...
November 14, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29132695/thai-clinicians-attitudes-toward-antimicrobial-stewardship-programs
#9
Nantanit Sutthiruk, Julie Considine, Ana Hutchinson, Andrea Driscoll, Kumthorn Malathum, Mari Botti
BACKGROUND: Effective hospital-wide antimicrobial stewardship (AMS) programs need multidisciplinary engagement; however, clinicians' attitudes have not been investigated in Thailand where AMS is in early development. The aim of this study was to explore Thai clinicians' (doctors, nurses, and pharmacists) perceptions and attitudes toward AMS. METHODS: A paper-based survey was distributed in a 1,000-bed university hospital in Bangkok, Thailand, between November 9, 2015, and December 21, 2015...
November 10, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29130384/characterising-the-growth-in-palliative-care-prescribing-2011-2015-analysis-of-national-medical-and-non-medical-activity
#10
Lucy Ziegler, Michael I Bennett, Matt Mulvey, Tim Hamilton, Alison Blenkinsopp
BACKGROUND: The role of non-medical prescribers working in palliative care has been expanding in recent years and prescribers report improvements in patient care, patient safety, better use of health professionals' skills and more flexible team working. Despite this, there is a lack of empirical evidence to demonstrate its clinical and economic impact, limiting our understanding of the future role of non-medical prescribers within a healthcare system serving an increasing number of people with palliative care needs...
November 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/29128648/a-hypertension-emergency-department-intervention-aimed-at-decreasing-disparities-design-of-a-randomized-clinical-trial
#11
Heather M Prendergast, Marina Del Rios, Renee Petzel-Gimbar, Daniel Garside, Sara Heinert, Sandra Escobar-Schulz, Pavitra Kotini-Shah, Michael Brown, Jinsong Chen, Joseph Colla, Marian Fitzgibbon, Ramon A Durazo-Arvizu, Martha Daviglus
Effective interventions to identify and treat uncontrolled hypertension (HTN), particularly in underrepresented populations that use the emergency department (ED) for primary care, are critically needed. Uncontrolled HTN contributes significantly to cardiovascular morbidity and mortality and is more frequently encountered among patients presenting to the ED as compared to the primary care setting. EDs serve as the point of entry into the health care system for high-risk patient populations, including minority and low-income patients...
November 8, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29123599/patient-satisfaction-with-chronic-hiv-care-provided-through-an-innovative-pharmacist-nurse-managed-clinic-and-a-multidisciplinary-clinic
#12
Jason Kielly, Deborah V Kelly, Shabnam Asghari, Kim Burt, Jessica Biggin
Background: Pharmacist/nurse-led clinics are an established model for many chronic diseases but not yet for HIV. At our centre, patients with HIV are seen by a multidisciplinary team (physician, nurse, pharmacist, social worker) at least yearly. Some attend an HIV-specialist pharmacist/nurse clinic (or "nonphysician clinic," NPC) for alternate biannual visits. Our objective was to assess patient satisfaction with care received through both clinics. Methods: The Patient Satisfaction Survey for HIV Ambulatory Care (assesses satisfaction with access to care, clinic visits and quality of care) was administered by telephone to adults who attended either clinic between January and July 2014...
November 2017: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/29123479/knowledge-on-alzheimer-s-disease-among-public-hospitals-and-health-clinics-pharmacists-in-the-state-of-selangor-malaysia
#13
Thimarul Huda Mat Nuri, Yet Hoi Hong, Long Chiau Ming, Suhaidah Mohd Joffry, Muhamad Faiz Othman, Chin Fen Neoh
The prevalence of Alzheimer's disease (AD) has increased with the fast growing of aging population, thereby posing great challenges to provision of care for AD patients. Pharmacists play a vital role in the management of AD; this includes recognizing early symptoms of AD, providing medication counseling to AD patients and their caretakers, and identifying potential adverse drug reactions. A comprehensive understanding of the disease progression, as well as the pharmacological therapy, is essential to provide effective care to AD patients...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29123429/assessment-of-prescribed-medications-and-pattern-of-distribution-for-potential-drug-drug-interactions-among-chronic-kidney-disease-patients-attending-the-nephrology-clinic-of-lagos-university-teaching-hospital-in-sub-saharan-west-africa
#14
Olumuyiwa John Fasipe, Peter Ehizokhale Akhideno, Obiyo Nwaiwu, Alex Adedotun Adelosoye
Introduction: Life expectancy has increased significantly among chronic kidney disease (CKD) patients due to the extensive use of polypharmacy practice for medication prescriptions. This predisposes them to potential drug-drug interactions (DDIs), which can lead to an increase in morbidity, mortality, length of hospital stay, and health care cost. Methods: This was a 30-month retrospective study that reviewed the medical case records of consenting adult CKD patients from January 2014 to June 2016...
2017: Clinical Pharmacology: Advances and Applications
https://www.readbyqxmd.com/read/29122794/consensus-validation-of-the-posamino-potentially-serious-alcohol-medication-interactions-in-older-adults-criteria
#15
Alice E Holton, Paul J Gallagher, Cristín Ryan, Tom Fahey, Gráinne Cousins
OBJECTIVES: Older adults are particularly vulnerable to adverse effects from concurrent alcohol and medication use. However, there is limited evidence regarding the prevalence of these adverse outcomes among older adults, and there is a lack of consensus regarding what constitutes an alcohol-interactive medicine. The objective of this study was to develop an explicit list of potentially serious alcohol-medication interactions for use in older adults. DESIGN: Following a systematic review, review of drug compendia and clinical guidance documents, a two-round Delphi consensus method was conducted...
November 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/29121408/community-health-workers-supporting-clinical-pharmacists-in-diabetes-management-a-randomized-controlled-trial
#16
Lisa K Sharp, Jessica J Tilton, Daniel R Touchette, Yinglin Xia, Daniel Mihailescu, Michael L Berbaum, Ben S Gerber
OBJECTIVES: To evaluate the effectiveness of clinical pharmacists and community health workers (CHWs) in improving glycemic control within a low-income, ethnic minority population. METHODS: In a two-arm, 2-year, crossover trial, 179 African-American and 65 Hispanic adult patients with uncontrolled diabetes mellitus (hemoglobin A1c [HbA1c] ≥ 8%) were randomized to CHW support either during the first or second year of the study. All participants received clinical pharmacist support for both years of the study...
November 9, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/29121137/sweet-syndrome-induced-by-oral-acetaminophen-codeine-following-repair-of-a-facial-fracture
#17
Laurence M Bradley, Shauna P Higgins, Monee M Thomas, Ife J Rodney, Rebat M Halder
Sweet syndrome (SS), also known as acute febrile neutrophilic dermatosis, is an uncommon condition that is clinically characterized by painful, well-demarcated, indurated, erythematous plaques or nodules that typically favor the head, neck, and arms, and are accompanied by fever. The disease is divided into several categories based on the underlying etiology, with the drug-induced variant comprising a rising number of the total cases and being reported in association with an increasing number of medications...
September 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29121053/adept-a-semantically-enriched-pipeline-for-extracting-adverse-drug-events-from-free-text-electronic-health-records
#18
Ehtesham Iqbal, Robbie Mallah, Daniel Rhodes, Honghan Wu, Alvin Romero, Nynn Chang, Olubanke Dzahini, Chandra Pandey, Matthew Broadbent, Robert Stewart, Richard J B Dobson, Zina M Ibrahim
Adverse drug events (ADEs) are unintended responses to medical treatment. They can greatly affect a patient's quality of life and present a substantial burden on healthcare. Although Electronic health records (EHRs) document a wealth of information relating to ADEs, they are frequently stored in the unstructured or semi-structured free-text narrative requiring Natural Language Processing (NLP) techniques to mine the relevant information. Here we present a rule-based ADE detection and classification pipeline built and tested on a large Psychiatric corpus comprising 264k patients using the de-identified EHRs of four UK-based psychiatric hospitals...
2017: PloS One
https://www.readbyqxmd.com/read/29119468/clinical-decision-support-and-optional-point-of-care-testing-of-renal-function-for-safe-use-of-antibiotics-in-elderly-patients-a-retrospective-study-in-community-pharmacy-practice
#19
Mette Heringa, Annemieke Floor-Schreudering, Peter A G M De Smet, Marcel L Bouvy
OBJECTIVE: The aim was to investigate the management of drug therapy alerts on safe use of antibiotics in elderly patients with (potential) renal impairment and the contribution of optional creatinine point of care testing (PoCT) in community pharmacy practice. METHODS: Community pharmacists used a clinical decision support system (CDSS) for seven antibiotics. Alerts were generated during prescription processing in the case of previously registered renal impairment and when no information on renal function was available for patients aged 70 and over...
November 8, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/29118291/-outcomes-of-pharmaceutical-faculty-focused-introduction-to-nursing-education-for-pharmacy-students-a-questionnaire-survey
#20
Takashi Majima, Hiroshi Ohara
  The scope of pharmaceutical education in Japan has been expanding, and with it an awareness of the importance of team medical care. However, pharmaceutical education still gives little attention to the psychosocial aspects of care, instead focusing on the structures and functions of drugs. In contrast, nursing education emphasizes the fact that medical care involves patients' family and significant others as much as the patients themselves, and thus nursing students are taught the basic needs and developmental stages of those people requiring care alongside their practical nursing skills...
November 9, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
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