keyword
MENU ▼
Read by QxMD icon Read
search

Pneumococcal invasive disease

keyword
https://www.readbyqxmd.com/read/29029127/antibody-kinetics-and-response-to-routine-vaccinations-in-infants-born-to-women-who-received-an-investigational-trivalent-group-b-streptococcus-polysaccharide-crm197-conjugate-vaccine-during-pregnancy
#1
Shabir A Madhi, Anthonet Koen, Clare L Cutland, Lisa Jose, Niresha Govender, Frederick Wittke, Morounfolu Olugbosi, Ajoke Sobanjo-Ter Meulen, Sherryl Baker, Peter M Dull, Vas Narasimhan, Karen Slobod
Background: Maternal vaccination against group B Streptococcus (GBS) might provide protection against invasive GBS disease in infants. We investigated the kinetics of transplacentally transferred GBS serotype-specific capsular antibodies in the infants and their immune response to diphtheria toxoid and pneumococcal vaccination. Methods: This phase 1b/2, observer-blind, single-center study (NCT01193920) enrolled infants born to women previously randomized (1:1:1:1) to receive either GBS vaccine at dosages of 0...
September 23, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29025402/rates-of-and-risk-factors-for-septic-arthritis-in-patients-with-invasive-pneumococcal-disease-prospective-cohort-study
#2
Thomas J Marrie, Gregory J Tyrrell, Sumit R Majumdar, Dean T Eurich
BACKGROUND: There are many case reports of septic arthritis complicating invasive pneumococcal disease (IPD); however, no study has compared patients with IPD with septic arthritis to those who didn't develop septic arthritis Thus, we aimed to determine the rates of, and risk factors for, septic arthritis in patients with invasive pneumococcal disease (IPD). METHODS: Socio-demographic, clinical, and serological data were captured on all patients with IPD in Northern Alberta, Canada from 2000 to 2014...
October 12, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29021946/predictors-of-pneumococcal-carriage-and-the-effect-of-the-13-valent-pneumococcal-conjugate-vaccination-in-the-western-australian-aboriginal-population
#3
Deirdre A Collins, Anke Hoskins, Thomas Snelling, Kalpani Senasinghe, Jacinta Bowman, Natalie A Stemberger, Amanda J Leach, Deborah Lehmann
BACKGROUND: The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced to prevent invasive pneumococcal disease (IPD) in Western Australian (WA) Aboriginal people in 2001. PCV13 replaced PCV7 in July 2011, covering six additional pneumococcal serotypes; however, IPD rates remained high in Aboriginal people in WA. Upper respiratory tract pneumococcal carriage can precede IPD, and PCVs alter serotype distribution. METHODS: To assess the impact of PCV13 introduction, identify emerging serotypes, and assess risk factors for carriage, nasopharyngeal swabs and information on demographic characteristics, health, medication and living conditions from Aboriginal children and adults across WA from August 2008 to November 2014 were collected...
2017: Pneumonia
https://www.readbyqxmd.com/read/29021105/invasive-pneumococcal-pneumonia-caused-by-13-valent-pneumococcal-conjugate-vaccine-types-in-children-with-different-schedules
#4
Hong-Yi Lee, Yu-Chia Hsieh, Ching-Chuan Liu, Yi-Chuan Huang, Kuang-Yi Chang, Hsin Chi, Luan-Yin Chang, Yhu-Chering Huang, Li-Min Huang
BACKGROUND: In Taiwan, the age group with the greatest incidence of invasive pneumococcal disease is 2-5 years of age, which is different from other countries. This study was conducted to identify risk factors and different 13-valent pneumococcal conjugate vaccine (PCV13) schedules associated with vaccine-type invasive pneumococcal pneumonia (IPP) despite prior vaccination. METHODS: A case-control study was conducted prospectively between August 2012 and December 2015 at five participating medical centers...
September 27, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29020313/trends-in-invasive-pneumococcal-disease-ipd-in-cancer-patients-after-the-introduction-of-7-valent-pneumococcal-conjugate-vaccine-pcv7-a-20-year-longitudinal-study-at-a-major-urban-cancer-center
#5
Yeon Joo Lee, Yao-Ting Huang, Seong Jin Kim, Marina Kerpelev, Victoria Gonzalez, Anna Kaltsas, Genovefa Papanicolaou
Background: Rates of invasive pneumococcal disease (IPD) declined since routine childhood immunization with the 7-valent pneumococcal conjugate vaccine (PCV7) in 2000. We studied the impact of PCV7 on the incidence of IPD in cancer patients. Methods: This was a retrospective analysis of adult and pediatric patients treated at Memorial Sloan Kettering Cancer Center from 1992 to 2012. Recovery of Streptococcus pneumoniae from a sterile site defined IPD. IPD incidence was calculated as cases per 1,000 unique patient-visits per year (UPV)...
August 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020230/effect-of-maternally-derived-anti-protein-and-anti-capsular-igg-antibodies-on-the-rate-of-acquisition-of-nasopharyngeal-carriage-of-pneumococcus-in-newborns
#6
John Ojal, David Goldblatt, Caroline Tigoi, J Anthony G Scott
Background: In developing countries, introduction of pneumococcal conjugate vaccine has not eliminated circulation of vaccine serotypes. Vaccinating pregnant mothers to increase antibody concentrations in their newborn infants may reduce the acquisition of pneumococcal carriage and subsequent risk of disease. We explored the efficacy of passive immunity, attributable to anti-protein and anti-capsular pneumococcal antibodies, against acquisition of carriage. Methods: We examined the rate of nasopharyngeal acquisition of pneumococci in the first 90 days of life associated with varying anti-capsular and anti-protein antibody concentrations in infant cord/maternal venous blood in Kilifi, Kenya...
August 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020171/comparison-of-the-impact-of-pcv10-or-pcv13-on-invasive-pneumococcal-disease-in-equivalent-populations
#7
Pontus Naucler, Ilias Galanis, Eva Morfeldt, Jessica Darenberg, Åke Örtqvist, Birgitta Henriques-Normark
Background: Conjugated pneumococcal vaccines, PCV10 or PCV13, are used in childhood immunization programs worldwide, but direct comparisons of impacts against invasive pneumococcal disease (IPD) in equivalent populations have not been performed. We used the unique opportunity in Sweden, where the 21 counties use either PCV10 or PCV13 (introduced 2009-2010), to compare the vaccines (pre-vaccination 2007-2009 versus post-vaccination 2013-2016). Methods: All IPD episodes (n=16992) were recorded in Sweden during 2005-2016...
August 3, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28992176/disproportionate-exposure-to-antibiotics-in-children-at-risk-for-invasive-pneumococcal-disease-potential-for-emerging-resistance-and-opportunity-for-antibiotic-stewardship
#8
Tamar F Barlam, Jake R Morgan, Warren A Kaplan, Kevin Outterson, Stephen I Pelton
We compared antibiotic prescribing for children with and those without an underlying chronic condition associated with increased risk for invasive pneumococcal disease. Children with a chronic condition had significantly greater cumulative exposure to antibiotics and higher rates of prescriptions per person-year than those without a chronic condition; this population is at increased risk for the emergence of multidrug-resistant pathogens.
September 7, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28978716/immunization-antibiotic-use-and-pneumococcal-colonization-over-a-15-year-period
#9
Grace M Lee, Ken Kleinman, Stephen Pelton, Marc Lipsitch, Susan S Huang, Matt Lakoma, Maya Dutta-Linn, Melisa Rett, William P Hanage, Jonathan A Finkelstein
BACKGROUND: Rates of invasive pneumococcal disease have declined since widespread introduction of pneumococcal conjugate vaccines (PCVs) in the United States. We evaluated the impact of immunization status and recent antibiotic use on an individual child's risk of colonization. METHODS: This study extends previously reported data from children <7 years of age seen for well child or acute care visits in Massachusetts communities. Nasopharyngeal swabs were collected during 6 surveillance seasons from 2000 to 2014...
October 4, 2017: Pediatrics
https://www.readbyqxmd.com/read/28978509/development-of-an-extended-specificity-multiplex-immunoassay-for-detection-of-streptococcus-pneumoniae-serotype-specific-antigen-in-urine-using-human-monoclonal-antibodies
#10
Seyi D Eletu, Carmen L Sheppard, Elizabeth Thomas, Kenneth Smith, Priya Daniel, David J Litt, Wei Shen Lim, Norman K Fry
Current pneumococcal vaccines cover the most common 10 to 23 serotypes of the 92 presently described. However, with the increased usage of pneumococcal serotype-based vaccines the risk of serotype-replacement and an increase in disease caused by non-vaccine serotypes remains. Serotype surveillance of pneumococcal infection relies heavily on culture techniques, which are known to be insensitive, particularly in non-invasive disease.Pneumococcal serotype-specific urine assays offer an alternative method of serotyping both invasive and non-invasive disease...
October 4, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28973947/semisynthetic-glycoconjugate-vaccine-candidate-against-streptococcus-pneumoniae-serotype-5
#11
Marilda P Lisboa, Naeem Khan, Christopher Martin, Fei-Fei Xu, Katrin Reppe, Andreas Geissner, Subramanian Govindan, Martin Witzenrath, Claney L Pereira, Peter H Seeberger
Glycoconjugate vaccines based on isolated capsular polysaccharide (CPS) save millions of lives annually by preventing invasive pneumococcal disease caused by Streptococcus pneumoniae Some components of the S. pneumoniae glycoconjugate vaccine Prevnar13 that contains CPS antigens from 13 serotypes undergo modifications or degradation during isolation and conjugation, resulting in production problems and lower efficacy. We illustrate how stable, synthetic oligosaccharide analogs of labile CPS induce a specific protective immune response against native CPS using S...
October 2, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28968897/comparative-genomic-analysis-and-in-vivo-modelling-of-streptococcus-pneumoniae-st3081-and-st618-isolates-reveal-key-genetic-and-phenotypic-differences-contributing-to-clonal-replacement-of-serotype-1-in-the-gambia
#12
Laura Bricio-Moreno, Chinelo Ebruke, Chrispin Chaguza, Jennifer Cornick, Brenda Kwambana-Adams, Marie Yang, Grant Mackenzie, Brendan W Wren, Dean Everett, Martin Antonio, Aras Kadioglu
Streptococcus pneumoniae serotype 1 is one of the leading causes of invasive pneumococcal disease (IPD) in West Africa, with ST618 being the dominant cause of IPD in The Gambia. Recently however, a rare example of clonal replacement was observed, where the ST3081 clone of serotype 1 replaced the predominant ST618 clone as the main cause of IPD. In this study, we seek to find the reasons for this unusual replacement event. Using whole genome sequence analysis and clinically relevant models of in vivo infection, we identify distinct genetic and phenotypic characteristics of the emerging ST3081 clone...
September 14, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28968016/-molecular-characterization-of-non-vaccine-streptococcus-pneumoniae-serotypes-11a-15-b-c-and-23a-recovered-from-invasive-isolates-in-colombia
#13
Paola Andrea Palacios, Carolina Duarte, Olga Sanabria, Jaime Moreno
INTRODUCTION: A total of 192 invasive Streptococcus pneumoniae isolates, from serotypes 11A, 15B/C and 23A (not included in the conjugated vaccines), were collected in Colombia between 1994 and 2014 as part of the activities of the Network surveillance system for the causative agents of pneumonia and meningitis (SIREVA II). OBJECTIVE: To determine the molecular characteristics of invasive S. pneumoniae isolates from serotypes 11A, 15B/C and 23A in Colombia from 1994 to 2014...
September 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28961675/nasopharyngeal-pneumococcal-colonization-and-impact-of-a-single-dose-of-13-valent-pneumococcal-conjugate-vaccine-in-indian-children-with-hiv-and-their-unvaccinated-parents
#14
Bikas K Arya, Sangeeta Das Bhattacharya, Catherine G Sutcliffe, Feroze Ganaie, Arun Bhaskar, Subhasish Bhattacharyya, Swapan Kumar Niyogi, William J Moss, Samiran Panda, K L Ravikumar, Ranjan Saurav Das, Sutapa Mandal
BACKGROUND: HIV infection increases risk of invasive disease from Streptococcus pneumoniae. Pneumococcal conjugate vaccines (PCV) prevent invasive disease and acquisition of vaccine type (VT) pneumococcus in the nasopharynx. OBJECTIVE: To look at the safety and impact of one dose of PCV13 on acquisition of VT pneumococcal carriage in Indian children with HIV. METHOD: We conducted a cohort study in families of HIV-infected children (CLH) and families of HIV-uninfected children (HUC) in West Bengal...
September 27, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28955497/pneumococcal-vaccination-in-autoimmune-rheumatic-diseases
#15
REVIEW
Éva Rákóczi, Zoltan Szekanecz
Streptococcus pneumoniae is the leading cause of the community-acquired pneumonia. The mortality rate of invasive pneumococcal infections is high. Immunocompromised patients suffering from autoimmune inflammatory rheumatic diseases (AIRD) have a high risk for acquiring these infections. Protection against infection can be improved with vaccination. After using polysaccharide vaccines (PPV-23), in July 2013, a 13-valent conjugate vaccine (PCV-13) was approved for adults. Due to its conjugate form, this vaccine is the recommended choice in pneumococcal vaccine-naive patients...
2017: RMD Open
https://www.readbyqxmd.com/read/28951137/a-pharmacist-driven-academic-detailing-program-to-increase-adult-pneumococcal-vaccination
#16
Aisling R Caffrey, Jennifer M DeAngelis, Kristina E Ward, K Kelly Orr, Haley J Morrill, Michael Gosciminski, Kerry L LaPlante
OBJECTIVES: To describe our statewide, pharmacist-led education campaign to increase knowledge and awareness of pneumococcal immunization recommendations. SETTING: Immunization providers and residents in the state of Rhode Island. PRACTICE DESCRIPTION: A clinical pathway (i.e., decision-support tool) was developed to educate health professionals about appropriate indications, administration schedules, and frequently asked questions for the 2 different adult pneumococcal vaccines...
September 23, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28951105/epidemiology-of-invasive-pneumococcal-and-haemophilus-influenzae-diseases-in-northwestern-ontario-canada-2010-2015
#17
Vic Eton, Annette Schroeter, Len Kelly, Michael Kirlew, Raymond S W Tsang, Marina Ulanova
INTRODUCTION: North American Indigenous populations experience a high burden of invasive bacterial infections. Because Streptococcus pneumoniae and Haemophilus influenzae (Hi) have multiple antigenic variants, the existing vaccines cannot prevent all cases. This study addresses current epidemiology of invasive Hi and pneumococcal disease (IPD) in a region of Northwestern Ontario, Canada with a relatively high (82%) Indigenous population. METHODS: Data were retrieved from retrospective chart review at a hospital servicing a population of 29,000 (82% Indigenous), during January 2010-July 2015...
September 22, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28945368/a-streptococcus-pneumoniae-type-2-oligosaccharide-glycoconjugate-elicits-opsonic-antibodies-and-is-protective-in-an-animal-model-of-invasive-pneumococcal-disease
#18
Madhu Emmadi, Naeem Khan, Lennart Lykke, Katrin Reppe, Sharavathi G Parameswarappa, Marilda P Lisboa, Sandra-Maria Wienhold, Martin Witzenrath, Claney L Pereira, Peter H Seeberger
Invasive pneumococcal diseases (IPDs) remain the leading cause of vaccine-preventable childhood death, even though highly effective pneumococcal conjugate vaccines (PCVs) are used in national immunization programs in many developing countries. Licensed PCVs currently cover only 13 of the over 90 serotypes of Streptococcus pneumoniae (Sp), so nonvaccine serotypes are a major obstacle to the effective control of IPD. Sp serotype 2 (ST2) is such a nonvaccine serotype that is the main cause of IPD in many countries, including Nepal, Bangladesh, and Guatemala...
October 4, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28941358/rates-of-vaccination-against-streptococcus-pneumoniae-in-cochlear-implant-patients
#19
Anna Piotrowska, Iwona Paradowska-Stankiewicz, Henryk Skarżyński
BACKGROUND Streptococcus pneumoniae can cause life-threatening illness, with invasive pneumococcal diseases (IPD) like meningitis, sepsis, bacteremic pneumonia, and bacteremia being major causes of morbidity and mortality. Studies have shown that patients who have had a cochlear implant, particularly children, have an increased risk of bacterial (pneumococcal) meningitis. Vaccination in patients with cochlear implants is important and recommended universally. The World Health Organization recommends the use of pneumococcal conjugate vaccines in all countries and considers their use to be a priority in all national immunization programs...
September 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28932211/strain-level-streptococcus-colonization-patterns-during-the-first-year-of-life
#20
Meredith S Wright, Jamison McCorrison, Andres M Gomez, Erin Beck, Derek Harkins, Jyoti Shankar, Stephanie Mounaud, Edelwisa Segubre-Mercado, Aileen May R Mojica, Brian Bacay, Susan A Nzenze, Sheila Z M Kimaro, Peter Adrian, Keith P Klugman, Marilla G Lucero, Karen E Nelson, Shabir Madhi, Granger G Sutton, William C Nierman, Liliana Losada
Pneumococcal pneumonia has decreased significantly since the implementation of the pneumococcal conjugate vaccine (PCV), nevertheless, in many developing countries pneumonia mortality in infants remains high. We have undertaken a study of the nasopharyngeal (NP) microbiome during the first year of life in infants from The Philippines and South Africa. The study entailed the determination of the Streptococcus sp. carriage using a lytA qPCR assay, whole metagenomic sequencing, and in silico serotyping of Streptococcus pneumoniae, as well as 16S rRNA amplicon based community profiling...
2017: Frontiers in Microbiology
keyword
keyword
66338
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"