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https://www.readbyqxmd.com/read/29333752/workplace-design-for-the-australian-residential-aged-care-workforce
#1
Lucio Naccarella, Clare Newton, Alan Pert, Kurt Seemann, Ruth Williams, Kate Sellick, Briony Dow
OBJECTIVES: This research explored residential aged care (RAC) workplace design features that influence how RAC staff feel valued, productive, safe, like they belong and connected. A secondary aim was to validate emerging themes about RAC design features with stakeholders. METHODS: A multistage qualitative study was conducted in one RAC facility with 100 residents in outer metropolitan Melbourne: (i) photo-elicitation - photographs were used to prompt discussions with RAC staff; (ii) individual interviews with RAC directors; and (iii) validity testing with the advisory committee occurred...
January 14, 2018: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29333422/epigenetic-inactivation-of-runx3-in-colorectal-cancer
#2
Eung Jin Shin, Han Jo Kim, Myoung Won Son, Tae Sung Ahn, Hyun Yong Lee, Dae Ro Lim, Sang Byung Bae, Seob Jeon, Hyungjoo Kim, Dongjun Jeong, Moon Soo Lee, Dong-Sun Kim, Jeong Se Noh, Moo-Jun Baek
Purpose: Emerging evidence indicates that runt-related transcription factor 3 (RUNX3) is an important tumor suppressor gene in several cancer types, including colorectal cancer (CRC). However, the clinical significance of RUNX3 inactivation in CRC remains unclear. The aim of this study was to examine the correlation between clinicopathologic factors and RUNX3 hypermethylation/expression in CRC. Methods: Sixty-two CRC patients who were treated at the Soonchunhyang University College of Medicine were recruited in this study...
January 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29333111/diet-gut-microbiota-and-colorectal-cancer-prevention-a-review-of-potential-mechanisms-and-promising-targets-for-future-research
#3
Mingyang Song, Andrew T Chan
Diet plays an important role in the development of colorectal cancer. Emerging data have implicated the gut microbiota in colorectal cancer. Diet is a major determinant for the gut microbial structure and function. Therefore, it has been hypothesized that alterations in gut microbes and their metabolites may contribute to the influence of diet on the development of colorectal cancer. We review several major dietary factors that have been linked to gut microbiota and colorectal cancer, including major dietary patterns, fiber, red meat and sulfur, and obesity...
December 2017: Current Colorectal Cancer Reports
https://www.readbyqxmd.com/read/29332773/does-medical-staffing-influence-perceived-safety-an-international-survey-on-medical-crew-models-in-helicopter-emergency-medical-services
#4
Kristen Rasmussen, Jo Røislien, Stephen J M Sollid
OBJECTIVE: The competence, composition, and number of crewmembers have generally been considered to influence the degree of patient care and safety in helicopter emergency medical services (HEMS), but evidence to support the advantages of one crew concept over another is ambiguous; additionally, the benefit of physicians as crewmembers is still highly debated. METHODS: To compare perceived safety in different medical crew models, we surveyed international HEMS medical directors regarding the types of crew compositions their system currently used and their supportive rationales and to evaluate patient and flight safety within their services...
January 2018: Air Medical Journal
https://www.readbyqxmd.com/read/29332542/long-journeys-toward-freedom-the-relationship-between-coercive-control-and-space-for-action-measurement-and-emerging-evidence
#5
Nicola Sharp-Jeffs, Liz Kelly, Renate Klein
We report on the development of, and findings from, two scales measuring coercive control and space for action over a period of 3 years in a sample of 100 women who had accessed domestic violence services. We present statistical evidence to show a significant correlation between coercive control and space for action. However, dealing with violence is not a linear process, and support needs to extend beyond being enabled to separate. The scales advance measurement of women's experience of coercive control and, through the space for action scale, document their ability to restore agency and freedom in contexts of relative safety...
February 2018: Violence Against Women
https://www.readbyqxmd.com/read/29332327/stage-ii-thymoma-and-emergency-coronary-artery-bypass-to-irradiate-or-not-to-irradiate-to-avoid-radiation-induced-vascular-injury-case-report-and-literature-review
#6
Ilias A Kouerinis, Maria Tolia, Flora Zagouri, Michail Nikolaou, Nikolaos Tsoukalas, George Kyrgias, Meletios A Dimopoulos, Charalambos Vlachopoulos, Ioannis Karathanassis, Christina K Zoubouli, Ioannis Kokakis, Vasileios Kouloulias, Konstantinos Triantafillou
PURPOSE: The purpose of this study was to present the controversial role of adjuvant radiotherapy to a 72-year-old male patient with Masaoka stage II thymoma and coronary artery bypass and to review the relevant literature. METHODS: The data were collected by relevant studies on PubMed and EMBASE. Articles up to March 2017 were included. RESULTS: Although the radiation-induced vascular injury to the internal thoracic artery and its suitability for grafting in a patient who is candidate for coronary artery bypass is documented, the possible catastrophic effect of adjuvant radiotherapy to existing grafts in a patient with prior bypass surgery has not been fully investigated...
November 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29332310/advances-and-current-challenges-in-calcium-signaling
#7
REVIEW
Jörg Kudla, Dirk Becker, Erwin Grill, Rainer Hedrich, Michael Hippler, Ursula Kummer, Martin Parniske, Tina Romeis, Karin Schumacher
Content I. II. III. IV. V. VI. VII VIII IX X XI ORCID References SUMMARY: Temporally and spatially defined changes in Ca2+ concentration in distinct compartments of cells represent a universal information code in plants. Recently, it has become evident that Ca2+ signals not only govern intracellular regulation but also appear to contribute to long distance or even organismic signal propagation and physiological response regulation. Ca2+ signals are shaped by an intimate interplay of channels and transporters, and during past years important contributing individual components have been identified and characterized...
January 14, 2018: New Phytologist
https://www.readbyqxmd.com/read/29332303/mitochondrial-dna-nuclear-context-and-the-risk-for-carcinogenesis
#8
REVIEW
Brett A Kaufman, Martin Picard, Neal Sondheimer
The inheritance of mitochondrial DNA (mtDNA) from mother to child is complicated by differences in the stability of the mitochondrial genome. Although the germ line mtDNA is protected through the minimization of replication between generations, sequence variation can occur either through mutation or due to changes in the ratio between distinct genomes that are present in the mother (known as heteroplasmy). Thus, the unpredictability in transgenerational inheritance of mtDNA may cause the emergence of pathogenic mitochondrial and cellular phenotypes in offspring...
January 14, 2018: Environmental and Molecular Mutagenesis
https://www.readbyqxmd.com/read/29332237/acute-acetaminophen-ingestion-improves-performance-and-muscle-activation-during-maximal-intermittent-knee-extensor-exercise
#9
Paul T Morgan, Joanna L Bowtell, Anni Vanhatalo, Andrew M Jones, Stephen J Bailey
AIM: Acetaminophen is a commonly used medicine for pain relief and emerging evidence suggests that it may improve endurance exercise performance. This study investigated some of the physiological mechanisms by which acute acetaminophen ingestion might blunt muscle fatigue development. METHODS: Thirteen active males completed 60 × 3 s maximum voluntary contractions (MVC) of the knee extensors with each contraction separated by a 2 s passive recovery period...
January 13, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29332000/how-good-are-doctors-at-introducing-themselves-hellomynameis
#10
Peter Gillen, Sue Faye Sharifuddin, Muireann O'Sullivan, Alison Gordon, Eva M Doherty
BACKGROUND: This explorative study was triggered by the '#hellomynameis' campaign initiated by Dr Kate Granger in the UK. Our objectives were twofold: first, to measure rates of introduction in an Irish hospital setting by both consultant and non-consultant hospital doctors. Second to establish whether such practices were associated with patient perceptions of the doctor/patient interaction. METHOD: A patient 'exit' survey was undertaken following doctor-patient consultations in both acute (surgical and medical assessment units) and elective settings (outpatient clinics)...
January 13, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29331949/bibliometric-analysis-of-military-trauma-publications-2000-2016
#11
Mark L Vickers, C P Coorey, G J Milinovich, L Eriksson, M Assoum, M C Reade
INTRODUCTION: Bibliometric tools can be used to identify the authors, topics and research institutions that have made the greatest impact in a field of medicine. The aim of this research was to analyse military trauma publications over the last 16 years of armed conflict in order to highlight the most important lessons that have translated into civilian practice and military doctrine as well as identify emerging areas of importance. METHODS: A systematic search of research published between January 2000 and December 2016 was conducted using the Thompson Reuters Web of Science database...
January 13, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29331730/exenatide-exerts-cognitive-effects-by-modulating-the-bdnf-trkb-neurotrophic-axis-in-adult-mice
#12
Manuela Bomba, Alberto Granzotto, Vanessa Castelli, Noemi Massetti, Elena Silvestri, Lorella M T Canzoniero, Annamaria Cimini, Stefano L Sensi
Modulation of insulin-dependent signaling is emerging as a valuable therapeutic tool to target neurodegeneration. In the brain, the activation of insulin receptors promotes cell growth, neuronal repair, and protection. Altered brain insulin signaling participates in the cognitive decline seen in Alzheimer's disease patients and the aging brain. Glucagon-like peptide-1 (GLP-1) regulates insulin secretion and, along with GLP-1 analogues, enhances neurotrophic signaling and counteracts cognitive deficits in preclinical models of neurodegeneration...
December 19, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29331711/omega-3-supplements-reduce-self-reported-physical-aggression-in-healthy-adults
#13
Laurent Bègue, Ap Zaalberg, Rébecca Shankland, Aaron Duke, Julie Jacquet, Perla Kaliman, Lucie Pennel, Marc Chanove, Philippe Arvers, Brad J Bushman
There is emerging evidence that Omega-3 polyunsaturated fatty acids (PUFA) supplements can decrease aggression. However, experimental studies with adults from non-specific populations are scarce. We hypothesized that Omega-3 supplements would decrease self-reported aggression among non-clinical participants. In a double-blind randomized trial, two groups of participants (N = 194) aged 18-45 from the general population followed a 6-weeks treatment with 638mg docosahexaenoic acid (DHA) and 772mg eicosapentaenoic acid (EPA) per day or the equivalent quantity of copra oil (placebo)...
December 15, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29331615/increased-brain-glucocorticoid-actions-following-social-defeat-in-rats-facilitates-the-long-term-establishment-of-social-subordination
#14
Meltem Weger, Yannick Sevelinges, Jocelyn Grosse, Isabelle Guillot de Suduiraut, Olivia Zanoletti, Carmen Sandi
Social rank is frequently established through aggressive encounters between new conspecifics. Despite increasing evidence suggesting that social rank is critical for the well-being of both humans and animals, knowledge about the factors influencing social rank remain scarce. Stress was previously shown to affect the establishment and maintenance of social hierarchies in rats. Likewise, increasing systemic corticosterone levels post-encounter in the emerging subordinate rat facilitates the long-term establishment of social subordination...
January 10, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29331493/hip-dislocations-in-the-emergency-department-a-review-of-reduction-techniques
#15
Michael Gottlieb
BACKGROUND: Hip dislocations are a common presentation in the Emergency Department (ED) and require urgent reduction to reduce the risk of avascular necrosis. Over 90% of all dislocations can successfully be reduced in the ED and there is evidence that cases awaiting operative reduction result in significant delays. DISCUSSION: While there is limited data comparing specific techniques, the individual success rates of most maneuvers range from 60-90%. Additionally, each technique has distinct advantages and limitations associated with its use...
January 10, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29331468/symposium-review-the-influences-of-heat-stress-on-bovine-mammary-gland-function
#16
S Tao, R M Orellana, X Weng, T N Marins, G E Dahl, J K Bernard
Heat stress reduces cow milk yield and results in a significant economic loss for the dairy industry. During lactation, heat stress lowers milk production by 25 to 40% with half of the decrease in milk synthesis resulting from the reduced feed intake. In vitro studies indicate that primary bovine mammary epithelial cells display greater rates of programmed cell death when exposed to high ambient temperatures, which may lead to a decrease in the total number of mammary epithelial cells in the mammary gland, partially explaining the lower milk production of lactating cows under heat stress...
January 10, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29331447/sharp-wave-ripples-as-a-signature-of-hippocampal-prefrontal-reactivation-for-memory-during-sleep-and-waking-states
#17
Wenbo Tang, Shantanu P Jadhav
It is widely believed that memories that are encoded and retrieved during waking behavior are consolidated during sleep. Recent studies on the interactions between the hippocampus and the prefrontal cortex have greatly advanced our understanding of the physiological bases of these memory processes. Although hippocampal-prefrontal network activity differs in many aspects during waking and sleep states, here we review evidence that hippocampal sharp-wave ripples (SWRs) emerge as a common neurophysiological pattern in both states, facilitating communication between these two regions via coordinated reactivation of stored memory information...
January 10, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29331404/reliability-and-validity-of-the-adapted-resistance-training-skills-battery-for-children
#18
Bonnie J Furzer, Marc D Bebich-Philip, Kemi E Wright, Siobhan L Reid, Ashleigh L Thornton
OBJECTIVES: Resistance training (RT) is emerging as a training modality to improve motor function and facilitate physical activity participation in children across the motor proficiency spectrum. Although RT competency assessments have been established and validated among adolescent cohorts, the extent to which these methods are suitable for assessing children's RT skills is unknown. This project aimed to assess the psychometric properties of the adapted Resistance Training Skills Battery for Children (RTSBc), in children with varying motor proficiency...
December 29, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29331271/the-durability-of-operational-improvements-with-rotational-patient-assignment
#19
Stephen J Traub, Soroush Saghafian, Adam C Bartley, Matthew R Buras, Christopher F Stewart, Brian T Kruse
INTRODUCTION: Previous work has suggested that Emergency Department rotational patient assignment (a system in which patients are algorithmically assigned to physicians) is associated with immediate (first-year) improvements in operational metrics. We sought to determine if these improvements persisted over a longer follow-up period. METHODS: Single-site, retrospective analysis focused on years 2-4 post-implementation (follow-up) of a rotational patient assignment system...
December 20, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29331055/the-challenges-and-possibilities-of-public-access-defibrillation
#20
REVIEW
Mattias Ringh, Jacob Hollenberg, Thea Palsgaard-Moeller, Leif Svensson, Mårten Rosenqvist, Freddy K Lippert, Mads Wissenberg, Carolina Malta Hansen, Andreas Claesson, Soren Viereck, Jolande A Zijlstra, Rudolph W Koster, Johan Herlitz, Marieke T Blom, Jo Kramer-Johansen, Hanno L Tan, Steffie Beesems, Michiel Hulleman, Theresa M Olasveengen, Fredrik Folke
Out-of-Hospital Cardiac Arrest (OHCA) is a major health problem that affects approximately four hundred thousand patients annually in the United States alone. It is a major challenge for the emergency medical system since decreased survival rates are directly proportional to the time delay from collapse to defibrillation. Historically, defibrillation has only been performed by physicians and in-hospital. With the development of automated external defibrillators (AEDs), rapid defibrillation by non-medical professionals and subsequently by trained or untrained lay bystanders has become possible...
January 13, 2018: Journal of Internal Medicine
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