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https://www.readbyqxmd.com/read/28915865/informed-consent-and-registry-based-research-the-case-of-the-danish-circumcision-registry
#1
Thomas Ploug, Søren Holm
BACKGROUND: Research into personal health data holds great potential not only for improved treatment but also for economic growth. In these years many countries are developing policies aimed at facilitating such research often under the banner of 'big data'. A central point of debate is whether the secondary use of health data requires informed consent if the data is anonymised. In 2013 the Danish Minister of Health established a new register collecting data about all ritual male childhood circumcisions in Denmark...
September 15, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/28912725/enhanced-strength-and-sprint-levels-and-changes-in-blood-parameters-during-a-complete-athletics-season-in-800-m-high-level-athletes
#2
Beatriz Bachero-Mena, Fernando Pareja-Blanco, Juan J González-Badillo
The purpose of this study was to analyze changes in sprint, strength, hematological, and hormonal parameters in high-level 800 m athletes during a complete athletics season. Thirteen male athletes of national and international level in 800 m (personal best ranging from 1:43 to 1:58 min:ss) participated in this study. A total of 5 tests were conducted during a complete athletics season. Athletes performed sprint tests (20 and 200 m), countermovement jump (CMJ), jump squat (JS), and full squat (SQ) tests. Blood samples (red and white blood profile) and hormones were collected in test 1 (T1), test 3 (T3), and test 5 (T5)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28872374/changes-in-choice-reaction-time-during-and-after-8-days-exhaustive-cycling-are-not-related-to-changes-in-physical-performance
#3
Twan Ten Haaf, Selma van Staveren, Danilo Iannetta, Bart Roelands, Romain Meeusen, Maria F Piacentini, Carl Foster, Leo Koenderman, Hein A M Daanen, Jos J de Koning
PURPOSE: Reaction time has been proposed as a training monitoring tool, but to date results are equivocal. Therefore, it was investigated whether reaction time can be used as a monitoring tool to establish overreaching. METHODS: The study included 30 subjects (11 female/19 male, age: 40.8±10.8 y, VO2max: 51.8±6.3 ml/kg/min) who participated in an 8-day cycling event. The external exercise load increased approximately 900% compared to the preparation period. Performance was measured before and after the event using a maximal incremental cycling test...
September 5, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28756009/flaws-in-the-lnt-single-hit-model-for-cancer-risk-an-historical-assessment
#4
REVIEW
Edward J Calabrese
The LNT single-hit model was derived from the Nobel Prize-winning research of Herman J. Muller who showed that x-rays could induce gene mutations in Drosophila and that the dose response for these so-called mutational events was linear. Lewis J. Stadler, another well-known and respected geneticist at the time, strongly disagreed with and challenged Muller's claims. Detailed evaluations by Stadler over a prolonged series of investigations revealed that Muller's experiments had induced gross heritable chromosomal damage instead of specific gene mutations as had been claimed by Muller at his Nobel Lecture...
October 2017: Environmental Research
https://www.readbyqxmd.com/read/28704885/submaximal-markers-of-fatigue-and-overreaching-implications-for-monitoring-athletes
#5
André Siegl, Elisa M Kösel, Nicholas Tam, Susanne Koschnick, Nelleke G Langerak, Sabrina Skorski, Tim Meyer, Robert P Lamberts
The regular monitoring of athletes is important to fine-tune training and detect early symptoms of overreaching. Therefore the aim of this study was to determine if a noninvasive submaximal running test could reflect a state of overreaching. 14 trained runners completed a noninvasive Lamberts Submaximal Running Test, one week before and 2 days after finishing an ultramarathon, and delayed onset of muscle soreness and the daily analysis of life demands for athletes questionnaire were also captured. After the ultramarathon, submaximal heart rate was lower at 70% (-3 beats) and 85% of peak treadmill running speed (P<0...
September 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28662152/does-external-pneumatic-compression-treatment-between-bouts-of-overreaching-resistance-training-sessions-exert-differential-effects-on-molecular-signaling-and-performance-related-variables-compared-to-passive-recovery-an-exploratory-study
#6
Cody T Haun, Michael D Roberts, Matthew A Romero, Shelby C Osburn, Christopher B Mobley, Richard G Anderson, Michael D Goodlett, David D Pascoe, Jeffrey S Martin
PURPOSE: We sought to compare the effects of external pneumatic compression (EPC) and sham when used concurrently with resistance training on performance-related outcomes and molecular measures related to recovery. METHODS: Twenty (N = 20) resistance-trained male participants (aged 21.6±2.4 years) were randomized to balanced sham or EPC intervention groups. The protocol consisted of 3 consecutive days of heavy, voluminous back squat exercise followed by EPC/sham treatment (Days2-4) and 3 consecutive days of recovery (Days5-7) with EPC/sham only on Days5-6...
2017: PloS One
https://www.readbyqxmd.com/read/28639438/body-composition-analysis-to-study-long-term-training-effects-in-elite-male-water-polo-athletes
#7
Giovanni Melchiorri, Valerio Viero, Roberto Sorge, Tamara Triossi, Alessandro Campagna, Stella L Volpe, Dalgisio Lecis, Virginia Tancredi, Angela Andreoli
BACKGROUND: Elite water polo athletes undergo heavy training programs throughout the year, but especially to prepare major competitions, such as the Olympics. Optimal athletic performance is a result of many factors, including proper management of the intensity and volume of training, nutrition and recovery between training sessions. When training is excessive in relation to recovery may occur non functional overreaching (NFO). NFO can degenerate into overtraining syndrome (OTS) resulting in a decrease in athletic performance, with likely changes in body weight and body composition...
June 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28607514/evolution-of-lymphoma-staging-and-response-evaluation-current-limitations-and-future-directions
#8
REVIEW
Joel Cunningham, Sunil Iyengar, Bhupinder Sharma
The accurate detection and precise assessment of therapeutic responses is critical to the optimal management of patients with lymphoma. Over the past 50 years, dramatic advances in technology have established imaging as the cornerstone of disease evaluation. However, the appropriate application of current techniques requires acknowledgement of their strengths and weaknesses, and appreciation of the full diversity of lymphoid neoplasms. The role of anatomical and functional imaging in detection, treatment escalation/de-escalation and prognostication of patients with lymphoma can be misinterpreted...
June 13, 2017: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/28597618/effects-of-resistance-training-overtraining-and-early-specialization-on-youth-athletes
#9
Benjamin K Walters, Connor R Read, A Reed Estes
INTRODUCTION: In 2014, 60 million youth ages 6-18 participated in some form of generalized athletics. 3.5 million children are injured annually participating in organized sport or recreational activities. While sound physical education can decrease the burden of youth sports injuries, the median annual physical education budget of $764 for United States elementary, middle and high schools may not allow enough flexibility to apply evidenced-based guidelines. EVIDENCE ACQUISITION: The topics were selected after a careful review of the 2016 National Strength and Conditioning Association Position Statement on Long-Term Athletic Development...
June 8, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28528420/soil-or-dust-for-health-risk-assessment-studies-in-urban-environment
#10
M Gabarrón, A Faz, J A Acosta
To identify the best material (soil or dust) to be selected for health-risk assessment studies, road dust and urban soil from three cities with different population densities were collected, and size fractions were analysed for metal content (Pb, Zn, Cu, Cd, Cr, Co, and Ni). Results showed similar distribution of the size particles among cities, predominating fractions between 75 and 2000 μm in road dust and particles below 75 μm in soil. Metals were mainly bound to PM10 in both soil and road dust increasing the risk of adverse health effects, overall through inhalation exposure...
May 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28499117/conclusion-overreach-in-alcohol-and-pregnancy-article-the-authors-reply
#11
Omayma Alshaarawy, James C Anthony
No abstract text is available yet for this article.
May 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28480859/the-effects-of-non-functional-overreaching-and-overtraining-on-autonomic-nervous-system-function-in-highly-trained-athletes
#12
T Kajaia, L Maskhulia, K Chelidze, V Akhalkatsi, Z Kakhabrishvili
Aim of the study was to compare the ANS functioning, as measured by heart rate variability (HRV), in athletes with non-functional overreaching (NFO) and overtraining syndrome (OTS) and in athletes without NFO/OTS. In 43 athletes with NFO/OTS, 40 athletes without NFO/OTS, as well as in 35 sedentary subjects the ANS function was evaluated with the Autonomic Balance Test, based on the HRV analysis of resting heart rate recordings. Results of the study show lower HRV and lower vagal influence along with increased sympathetic cardiovascular control in athletes with non-functional overreaching and particularly in athletes with overtraining, than in highly trained athletes without NFO/OTS...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28422523/can-the-lamberts-submaximal-cycle-test-reflect-overreaching-in-professional-cyclists
#13
Lieselot Decroix, Robert P Lamberts, Romain Meeusen
PURPOSE: The Lamberts and Lambert Submaximal Cycle Test (LSCT) consists of 3 stages during which cyclist's cycle for 6 minutes at 60%, 6 minutes at 80% and 3 minutes at 90% of their maximal heart rate, followed by one-minute recovery. It was the aim of this study to determine if the LSCT is able to reflect a state of functional overreaching in professional female cyclists during an 8-day training camp and the following recovery days. METHODS: Six professional female cyclists performed an LSCT on day 1, day 5 and day 8 of the training camp and 3 days after the training camp...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28188371/the-effect-of-functional-overreaching-on-parameters-of-autonomic-heart-rate-regulation
#14
Clint R Bellenger, Rebecca L Thomson, Eileen Y Robertson, Kade Davison, Maximillian J Nelson, Laura Karavirta, Jonathan D Buckley
PURPOSE: Correlations between fatigue-induced changes in performance and maximal rate of HR increase (rHRI) may be affected by differing assessment workloads. This study evaluated the effect of assessing rHRI at different workloads on performance tracking, and compared this with HR variability (HRV) and HR recovery (HRR). METHODS: Performance [5-min cycling time trial (5TT)], rHRI (at multiple workloads), HRV and HRR were assessed in 12 male cyclists following 1 week of light training (LT), 2 weeks of heavy training (HT) and a 10-day taper (T)...
March 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28187634/a-new-species-of-the-genus-i-alvinocaris-i-williams-and-chace-1982-crustacea-decapoda-caridea-alvinocarididae-from-the-manus-basin-hydrothermal-vents-southwest-pacific
#15
Yan-Rong Wang, Zhong-Li Sha
One new species of alvinocaridid Alvinocaris kexueae sp. nov. is described from hydrothermal vents on the Manus Basin, Southwest Pacific. This is the fifteenth species in Alvinocaris Williams & Chace, 1982. The new species is easily recognized by the combination of the rostrum distinctively overreaching the distal end of the antennular peduncle, and the armature of its dorsal and ventral margins; the unarmed third abdominal segment, and by the posterior margin of the telson having one triangular tooth medially and 6 pairs unequal spines...
January 25, 2017: Zootaxa
https://www.readbyqxmd.com/read/28121796/sil-6r-is-related-to-weekly-training-mileage-and-psychological-well-being-in-athletes
#16
Tom Cullen, Andrew W Thomas, Richard Webb, Thom Phillips, Michael G Hughes
INTRODUCTION: IL-6 has been ascribed both positive and negative roles in the context of exercise and training. The dichotomous nature of IL-6 signalling appears to be determined by the respective concentration of its receptors (both membrane-bound (IL-6R) and soluble (sIL-6R) forms). The purpose of the present study was to investigate the response of sIL-6R to long-term training, and to investigate the relationship between sIL-6R, self-reported measures of wellbeing, and upper respiratory illness symptoms (URS) in highly-trained endurance athletes...
January 24, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28045532/ultrathin-interface-regime-of-core-shell-magnetic-nanoparticles-for-effective-magnetism-tailoring
#17
Seung Ho Moon, Seung-Hyun Noh, Jae-Hyun Lee, Tae-Hyun Shin, Yongjun Lim, Jinwoo Cheon
The magnetic exchange coupling interaction between hard and soft magnetic phases has been important for tailoring nanoscale magnetism, but spin interactions at the core-shell interface have not been well studied. Here, we systematically investigated a new interface phenomenon termed enhanced spin canting (ESC), which is operative when the shell thickness becomes ultrathin, a few atomic layers, and exhibits a large enhancement of magnetic coercivity (HC). We found that ESC arises not from the typical hard-soft exchange coupling but rather from the large magnetic surface anisotropy (KS) of the ultrathin interface...
January 10, 2017: Nano Letters
https://www.readbyqxmd.com/read/27928217/effects-of-a-high-protein-and-omega-3-enriched-diet-with-or-without-creatine-supplementation-on-markers-of-soreness-and-inflammation-during-5-consecutive-days-of-high-volume-resistance-exercise-in-females
#18
Sara Hayward, Colin D Wilborn, Lem W Taylor, Stacie L Urbina, Jordan J Outlaw, Cliffa A Foster, Michael D Roberts
We examined if two different dietary interventions affected markers of soreness and inflammation over a 5-day high-volume resistance training protocol in females that resistance-trained 8 weeks prior. Twenty-eight females (age: 20 ± 1 yr; body mass: 63.5 ± 1.6 kg, height: 1.67 ± 0.01 m) completed 4 weeks of pre-training (weeks 1-4) followed by a subsequent 4-week training period along with a dietary intervention (weeks 5-8). Dietary interventions from weeks 5-8 included: a) no intervention (CTL, n = 10) b) a higher-protein diet supplemented with hydrolyzed whey protein (50 g/d) and omega-3 fatty acids (900 mg/d) (DI, n = 8), and c) the DI condition as well as creatine monohydrate (5 g/d) (DI+C, n = 10)...
December 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/27902548/leveraging-electronic-health-record-implementation-to-facilitate-clinical-and-operational-quality-improvement-in-an-ambulatory-surgical-clinic
#19
Joseph L Bobadilla, Cathy S Roe, Patricia Estes, Jennifer Lackey, Carol L Steltenkamp
The implementation of electronic health records is a challenging, complex process requiring significant resources. The temptation is to convert a paper process into electronic format. This strategy fosters a familiar product to the users but is fraught with pitfalls. We chose to utilize the opportunity of the implementation of an enterprise-wide ambulatory electronic health record to foster an overreaching clinical and operational improvement project in a multispecialty surgical ambulatory clinic practice. We interrogated every aspect of the practice: clinic design, scheduling, physical space, staffing, and clinical and operational workflows...
January 2017: Journal of Ambulatory Care Management
https://www.readbyqxmd.com/read/27834554/prediction-of-functional-overreaching-from-subjective-fatigue-and-readiness-to-train-after-only-3-days-of-cycling
#20
Twan Ten Haaf, Selma van Staveren, Erik Oudenhoven, Maria F Piacentini, Romain Meeusen, Bart Roelands, Leo Koenderman, Hein A M Daanen, Carl Foster, Jos J de Koning
PURPOSE: To investigate whether monitoring of easily measurable stressors and symptoms can be used to distinguish early between acute fatigue (AF) and functional overreaching (FOR). METHODS: The study included 30 subjects (11 female, 19 male; age 40.8 ± 10.8 y, VO2max 51.8 ± 6.3 mL · kg(-1) · min(-1)) who participated in an 8-d cycling event over 1300 km with 18,500 climbing meters. Performance was measured before and after the event using a maximal incremental test...
April 2017: International Journal of Sports Physiology and Performance
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