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Tsai-Ju Chien, Chia-Yu Liu, Ruey-Hwa Lu, Chin-Wei Kuo, Yang-Chao Lin, Chung-Hua Hsu
BACKGROUND: Traditional Chinese Medicine (TCM) has been used increasingly as complementary medicine in cancer care. Kuan-Sin-Yin (KSY) is a TCM decoction containing seven herbs known to cause immunomodulation or anticancer activity, and which are associated with the TCM concept of Qi and energy supply. Kuan-Sin-Yin has cytostatic effects on cancer cells in animal models. OBJECTIVE: The aim of this study is to evaluate the level of improvement in meridian energy and heart-rate variability (HRV) and to assess whether these observations are compatible with TCM theory...
December 2016: Complementary Therapies in Medicine
Tarannum Mansoori, Jayanthi Sivaswamy, Jahnavi Sai Gamalapati, Satish Gooty Agraharam, Nagalla Balakrishna
AIM: To image the radial peripapillary capillary (RPC) network with optical coherence tomography angiography (OCTA) and measure its capillary density (CD) in the normal human retina. MATERIALS AND METHODS: Fifty-two normal participants underwent OCTA imaging with RTVue XR 100 Avanti OCT. The angioflow enface RPCs network was extracted from OCTA and 8 peripapillary sectors with a sector angle of 45 degrees were selected for quantitative analysis: superior nasal, superior temporal, temporal upper, temporal lower, nasal upper, nasal lower, inferior nasal, and inferior temporal...
November 30, 2016: Journal of Glaucoma
Jun Ji, Yan Huang, Xia-Fei Wang, Zhe Ma, Huan-Gan Wu, Hyoyoung Im, Hui-Rong Liu, Lu-Yi Wu, Jing Li
Background. Clinical studies suggest that acupuncture and moxibustion therapy in ulcerative colitis (UC) can regulate bowel inflammation, and these treatments have the advantages of low rates of adverse reactions and recurrence as well as good long-term efficacy. We reviewed the current status of clinical studies of the treatment. Methods. Randomized controlled trials (RCTs) using the therapy as the major intervention for treating UC were included from 1995 to 2015. The extracted data mainly included diagnostic standards, treatment methods, selection of acupoints, treatment times and courses, and efficacy determination criteria...
2016: Gastroenterology Research and Practice
Megan Staples, Ning-Xia Fang, Rikki Ma Graham, Helen V Smith, Amy V Jennison
In this study we evaluated the performance of the SHIGA TOXIN QUIK CHEK (Techlab®, Blacksburg, VA) and the ImmunoCard STAT! Enterohaemorrhagic E. coli (EHEC) (Meridian BioScience, Cincinnati, OH, USA) assays as methods for qualitatively detecting the presence of Shiga toxin in human fecal specimens. A multiplex PCR for the detection of stx1 and stx2 was used as the standard for comparison. The SHIGA TOXIN QUIK CHEK detected all known Shiga toxin subtypes with the exception of Stx2f, while the ImmunoCard STAT! EHEC was unable to identify four of the seven Stx2 subtypes, including Stx2b and Stx2d...
March 10, 2016: Diagnostic Microbiology and Infectious Disease
Hermes G Garcia, Marc Otten, Marc Pyfer, Saurabh J Singhal, Alfred Marc Iloreta, Varun R Kshettry, Christopher J Farrell, Gurston Nyquist, Marc Rosen, James J Evans
The purpose of this study was to evaluate the effect of posterior septectomy size on surgical exposure and surgical freedom during the endoscopic transsphenoidal approach to the sella and parasellar region. Dissections were performed on 10 embalmed cadaver heads. Dissections started with wide bilateral sphenoidotomies, lateralization of middle turbinates, and a 5-mm posterior septectomy. The posterior septectomy was increased in 5-mm increments to a maximum of 35 mm, followed by bilateral middle turbinectomies...
December 2016: Journal of Neurological Surgery. Part B, Skull Base
David F Nichols, Lisa R Betts, Hugh R Wilson
BACKGROUND: Evidence for position sensitivity in object-selective visual areas has been building. On one hand, most of the relevant studies have utilized stimuli for which the areas are optimally selective and examine small sections of cortex. On the other hand, visual field maps established with nonspecific stimuli have been found in increasingly large areas of visual cortex, though generally not in areas primarily responsive to faces. METHODS: fMRI was used to study the position sensitivity of the occipital face area (OFA) and the fusiform face area (FFA) to both standard rotating wedge retinotopic mapping stimuli and quadrant presentations of synthetic facial stimuli...
November 2016: Brain and Behavior
Atsushi Kawahara, Yoshinori Takayanagi
AIM: The aim of this research was to evaluate vector analysis after implantation of toric intraocular lenses (IOLs) without deviation from the intended axis. METHODS: The study included 18 eyes of 16 patients who underwent cataract surgery with the insertion of a toric implant (AcrySof IQ Toric). The postoperative IOL meridian placement completely corresponded to that planned. Using vector analysis, surgically induced astigmatism (SIA) was derived from the refractive outcome versus the predicted postoperative keratometric astigmatism and was compared with targeted induced astigmatism (TIA)...
2016: Clinical Ophthalmology
Jong Eun Lee, Kyung Rim Sung, Ji Min Park, Joo Young Yoon, Sung Yong Kang, Sung Bae Park, Hyung Jin Koo
PURPOSE: To explore optic disc and peripapillary retinal nerve fiber layer (RNFL) features associated with glaucomatous optic disc (GOD) in young myopia. METHODS: Presence of GOD, optic disc tilt, and disc torsion were determined using fundus photographs. If the measured disc tilt ratio was >1.3, the optic disc was classified as tilted. Optic disc torsion was defined as a >15° deviation in the long axis of the optic disc from the vertical meridian. The average and four quadrants RNFL thicknesses were assessed using spectral domain optical coherence tomography (SD-OCT)...
November 11, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Philipp Nikolaus Hesse, Frank Bremmer
The existence of an association between numbers and space is known for a long time. The most prominent demonstration of this relationship is the spatial numerical association of response codes (SNARC) effect, describing the fact that participants' reaction times are shorter with the left hand for small numbers and with the right hand for large numbers, when being asked to judge the parity of a number (Dehaene et al., J. Exp. Psychol., 122, 371-396, 1993). The SNARC effect is commonly seen as support for the concept of a mental number line, i...
November 8, 2016: Vision Research
Fanyang Dang, Wang Zhang, Shouqian Chen, Hui Wang, Van Nhu Le, Jiaqian Yu, Zhigang Fan
This paper investigated the geometry and aberration characteristics of conicoidal conformal domes. First, on the basis of previous research, we got the expression that was suitable for describing the external surface of the conicoidal conformal dome. Based on the theory of differential geometry, this paper first proved that the Dupin index line of a quadric surface was an ellipsoid and the radius of curvature had extreme values in the meridian plane and sagittal plane. Then the uniform formulas of curvature which were suitable for ellipsoid, paraboloid, and hyperboloid were deduced in the meridian plane and sagittal plane, respectively...
November 1, 2016: Applied Optics
Yang Jae Kim, Michael C Knorz, Gerd U Auffarth, Chul Young Choi
PURPOSE: To analyze the change in anterior and posterior corneal curvature after cataract surgery using a Placido-dual rotating Scheimpflug device. METHODS: In a prospective cross-sectional study, corneal curvature was measured using the Galilei G4 device (Ziemer Ophthalmic Systems, Port, Switzerland) preoperatively and 1 week and 1, 3, and 6 months after cataract surgery with a temporal limbal self-sealing 2.2-mm incision. The surgically induced astigmatism (SIA) was determined on the anterior and posterior surfaces...
November 1, 2016: Journal of Refractive Surgery
David Miles, David Cameron, Igor Bondarenko, Lyudmila Manzyuk, Juan Carlos Alcedo, Roberto Ivan Lopez, Seock-Ah Im, Jean-Luc Canon, Yaroslav Shparyk, Denise A Yardley, Norikazu Masuda, Jungsil Ro, Neelima Denduluri, Stanislas Hubeaux, Cheng Quah, Carlos Bais, Joyce O'Shaughnessy
AIM: MERiDiAN evaluated plasma vascular endothelial growth factor-A (pVEGF-A) prospectively as a predictive biomarker for bevacizumab efficacy in metastatic breast cancer (mBC). METHODS: In this double-blind placebo-controlled randomised phase III trial, eligible patients had HER2-negative mBC previously untreated with chemotherapy. pVEGF-A was measured before randomisation to paclitaxel 90 mg/m(2) on days 1, 8 and 15 with either placebo or bevacizumab 10 mg/kg on days 1 and 15, repeated every 4 weeks until disease progression, unacceptable toxicity or consent withdrawal...
November 4, 2016: European Journal of Cancer
Elisabeth Hein, Stefan Blaschke, Bettina Rolke
Responses to targets that appear at a noncued position within the same object (invalid-same) compared to a noncued position at an equidistant different object (invalid-different) tend to be faster and more accurate. These cueing effects have been taken as evidence that visual attention can be object based (Egly, Driver, & Rafal, Journal of Experimental Psychology: General, 123, 161-177, 1994). Recent findings, however, have shown that the object-based cueing effect is influenced by object orientation, suggesting that the cueing effect might be due to a more general facilitation of attentional shifts across the horizontal meridian (Al-Janabi & Greenberg, Attention, Perception, & Psychophysics, 1-17, 2016; Pilz, Roggeveen, Creighton, Bennet, & Sekuler, PLOS ONE, 7, e30693, 2012)...
October 28, 2016: Attention, Perception & Psychophysics
Chang Rae Rho, Min-Ji Kim, Choun-Ki Joo
Purpose. To evaluate surgically induced astigmatism (SIA) and the average corneal power change in symmetric intrastromal corneal ring segment (ICRS) implantation. Methods. The study included 34 eyes of 34 keratoconus patients who underwent symmetric Intacs SK ICRS implantation. The corneal pocket incision meridian was the preoperative steep meridian. Corneal power data were obtained before and 3 months after Intacs SK ICRS implantation using scanning-slit topography. Polar value analysis was used to evaluate the SIA...
2016: Journal of Ophthalmology
Ann E Elsner, Toco Y P Chui, Lei Feng, Hong Xin Song, Joel A Papay, Stephen A Burns
Large individual differences in cone densities occur even in healthy, young adults with low refractive error. We investigated whether cone density follows a simple model that some individuals have more cones, or whether individuals differ in both number and distribution of cones. We quantified cones in the eyes of 36 healthy young adults with low refractive error using a custom adaptive optics scanning laser ophthalmoscope. The average cone density in the temporal meridian was, for the mean ± SD, 43216 ± 6039, 27466 ± 3496, 14996 ± 1563, and 12207 ± 1278 cones /mm(2) for 270, 630, 1480, and 2070 microns from the foveal center...
October 25, 2016: Vision Research
Leandro L de Souza, Fernanda L B de Araujo, Fernanda A M da Silva, Thaís S Mucciaroni, João E de Araujo
We previously showed that a yin meridian of the upper limb decreased electromyographic activity (root mean square) and muscle strength ipsilateral and contralateral to the side of stimulation. Here, we tested the upper trapezius (UT) muscle response after stimulation of a yang meridian of the upper limb, the small intestine (SI). Thirty-eight healthy volunteers were randomized into the following groups: UT muscle (SI14), distant of the UT muscle (SI8), without stimulation (CG), and sham (R3). An acupuncturist certificated by the Brazilian Society of Physical Therapists and Acupuncturists performed the needle insertion...
October 2016: Journal of Acupuncture and Meridian Studies
Manuel Garza-Leon, Hugo A Fuentes-de la Fuente, Ana V García-Treviño
PURPOSE: The purpose of the study was to assess the reproducibility of ocular biometry using the IOLMaster-700 in a healthy population. METHODS: This is a prospective, cross-sectional, observational reproducibility study. Ocular biometry was performed three times on each of 45 studied eyes. Flattest meridian (Kf) and the steepest meridian (Ks), central corneal thickness, axial length, anterior chamber depth, aqueous depth, lens thickness, and white-to-white distances were recorded...
October 21, 2016: International Ophthalmology
Sonika Patel, Carl T Talmo, Sumon Nandi
BACKGROUND: Taper corrosion at the modular junctions of total hip arthroplasty (THA) femoral stems are known to cause locally destructive adverse local tissue reaction (ALTR). However, the implants at risk remain to be fully elucidated. CASE REVIEW: We report the case of a 76-year-old woman with hip pain, abductor weakness, and sciatic nerve symptoms 2 years following metal-on-polyethylene THA. Serum cobalt levels were elevated, while chromium levels were normal...
November 10, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
Agostino S Vaiano, Elisabet Coronado Quitllet, Gaetano Zinzanella, Giacomo De Benedetti, Guido Caramello
PURPOSE: To assess the reproducibility and accuracy of ultrasound (US) measurements in determining the distance between corneoscleral limbus and retinal break and its relation with the distance measured by indirect ophthalmoscopy, in patients undergoing a laser retinopexy procedure. METHODS: Forty-four patients with a single retinal break, scheduled for laser a retinopexy procedure (26 phakic patients and 18 pseudophakic patients), underwent 5 repeated measurements by high-resolution US and 3 measurements (at the time of the laser procedure, 1 and 3 months) by indirect ophthalmoscopy with scleral indentation of the corneoscleral limbus-retinal break distance with a caliper...
October 17, 2016: Retina
Zhengwei Zhang, Yuanting Zhou, Zhifang Xie, Tiantian Chen, Yan Gu, Shui Lu, Zhifeng Wu
The purpose of the current study was to investigate the effect of topical atropine on choroidal thickness using spectral-domain optical coherence tomography. A total of 30 healthy eyes from 30 children were analyzed in this study. A single drop of 1% atropine gel was administered twice daily for a week. Choroidal thickness (CT) was measured using SD-OCT, and changes in CT before and after administration of the eye drops were analyzed at the subfovea and at 1.0-mm intervals (up to 3.0 mm) from the fovea at superior, inferior, nasal, and temporal locations...
October 7, 2016: Scientific Reports
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