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https://www.readbyqxmd.com/read/28811830/changes-of-blood-flux-at-bl21-and-points-along-bl-meridian-resulted-from-acupuncture-or-moxibustion-case-cross-design-study
#1
Guangjun Wang, Shuyong Jia, Hongyan Li, Ze Wang, Yuying Tian, Weibo Zhang
Acupuncture (Acup) and moxibustion (Moxi) are commonly used interventions in clinical practice. However, the difference between Acup and moxibustion mechanisms is unclear. In current study, blood perfusion responses resulted from Acup or Moxi at Weishu acupoint (BL21) and control points were explored, respectively. The time series of blood flux signals at BL21 and control points were transformed with Morlet wavelet, and the differences in each frequency interval were observed. The results suggested that acupoint response to different stimulation is a comprehensive process which related to all components of blood perfusion signals...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28810910/comprehensive-evaluation-of-gene-expression-signatures-in-response-to-electroacupuncture-stimulation-at-zusanli-st36-acupoint-by-transcriptomic-analysis
#2
Jing-Shan Wu, Hsin-Yi Lo, Chia-Cheng Li, Feng-Yuan Chen, Chien-Yun Hsiang, Tin-Yun Ho
BACKGROUND: Electroacupuncture (EA) has been applied to treat and prevent diseases for years. However, molecular events happened in both the acupunctured site and the internal organs after EA stimulation have not been clarified. METHODS: Here we applied transcriptomic analysis to explore the gene expression signatures after EA stimulation. Mice were applied EA stimulation at ST36 for 15 min and nine tissues were collected three hours later for microarray analysis...
August 15, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28810545/electroacupuncture-attenuates-learning-and-memory-impairment-via-activation-of-%C3%AE-7nachr-mediated-anti-inflammatory-activity-in-focal-cerebral-ischemia-reperfusion-injured-rats
#3
Jiao Liu, Chunyan Li, Hongwei Peng, Kunqiang Yu, Jing Tao, Ruhui Lin, Lidian Chen
Studies have reported that electroacupuncture (EA) may reduce learning and memory impairment following cerebral ischemic injury. However, the precise mechanism of action remains unclear. In the present study, the attenuation of focal cerebral ischemia/reperfusion injury by EA in rats was investigated. EA at the Baihui (DU 20) and Shenting (DU 24) acupoints was demonstrated to significantly improve performance in the Morris water maze task, with shortened latency time and increased frequency of passing the platform...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28810542/electroacupuncture-promotes-axonal-regeneration-in-rats-with-focal-cerebral-ischemia-through-the-downregulation-of-nogo-a-ngr-rhoa-rock-signaling
#4
Saie Huang, Danxia Huang, Jiapei Zhao, Lidian Chen
The purpose of the present study was to evaluate the effect of electroacupuncture (EA) on the axonal regeneration environment following cerebral ischemia injury and to investigate whether it was associated with Nogo-A/Nogo receptor (NgR)/RhoA/Rho-associated protein kinase (ROCK) signaling. Using a rat model of focal cerebral ischemia, the effects of EA at the Quchi (LI11) and Zusanli (ST36) acupoints on axonal growth inhibitory protein and axonal growth factors were assessed and the underlying molecular mechanisms were investigated...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28810350/-analysis-of-compiling-date-of-huang-di-nei-jing-huangdi-s-internal-classic
#5
W B Zhang, Y T Gao, H Y Li
There are Seven Medical Classics recorded in the Han shu Yi wen zhi(Bibliography in Annals of the Han Dynasty), among which the 18-volume Huang di nei jing (Huangdi's Internal Classic) is not the current edition of Ling shu (Miraculous Pivot) and Su wen(Plain Questions). The present edition of Huang di nei jing containing these two works might be merged in the Eastern Han Dynasty, benefited from the invention of Cai Lun's papermaking technique and the development of Nine needles, especially filiform needle manufacturing...
May 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28804223/the-effect-of-transcutaneous-electrical-acupoint-stimulation-on-inflammatory-response-in-patients-undergoing-limb-ischemia-reperfusion
#6
Yunchang Mo, Sijia Chen, Lili Yang, Ledan Huang, Dan Jin, Zhi Yu, Leilei Wang, Liangrong Wang, Shan Luo, Junlu Wang
Reperfusion after tourniquet use can induce inflammation and cause remote organ injury. We evaluated the therapeutic effect of transcutaneous electrical acupoint stimulation (TEAS) on inflammatory mediators and lung function in patients receiving lower limb tourniquets. Forty patients undergoing unilateral lower extremity surgery with tourniquet were randomly assigned to two groups: the TEAS group and ischemia-reperfusion (I/R) group. The C-C motif chemokine ligand 2 (CCL2), C-X-C motif chemokine ligand 8 (CXCL8), interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), and arterial blood gas analysis were measured preoperatively and 6 h after tourniquet removal...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28801421/electroacupuncture-for-treating-insomnia-in-patients-with-cancer-a-study-protocol-for-a-randomised-pilot-clinical-trial
#7
Mikyung Kim, Jung-Eun Kim, Hye-Yoon Lee, Ae-Ran Kim, Hyo-Ju Park, O-Jin Kwon, Bo-Kyung Kim, Jung Hyo Cho, Joo-Hee Kim
INTRODUCTION: Although insomnia is one of the most prevalent and disturbing symptoms among patients with cancer, it has not been properly managed. Electroacupuncture (EA) has received attention as a promising intervention for insomnia, and a few previous studies have reported that this intervention may be beneficial for treating insomnia in patients with cancer. The aim of this pilot study is to explore the feasibility and preliminary effectiveness of EA on the sleep disturbance of patients with cancer with insomnia using a subjective method, patient-reported questionnaires and an objective tool, actigraphy, to measure the quality of sleep...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28789647/evaluation-of-muscle-activity-bite-force-and-salivary-cortisol-in-children-with-bruxism-before-and-after-low-level-laser-applied-to-acupoints-study-protocol-for-a-randomised-controlled-trial
#8
Mônica da Consolação Canuto Salgueiro, Carolina Carvalho Bortoletto, Anna Carolina RattoTempestini Horliana, Ana Carolina Costa Mota, Lara Jansiski Motta, Pamella de Barros Motta, Raquel Agnelli MesquitaFerrari, Kristianne Porta Santos Fernandes, Sandra Kalil Bussadori
BACKGROUND: Bruxism is a repetitive activity that causes tooth wear, audible sounds, and discomfort. Preventive measures have been studied for conditions that can exert a negative influence on physiological development in children. Low-level laser therapy administered over acupoints is an effective, painless, low-cost treatment option that has achieved good results. Thus, the aim of the proposed study is to evaluate changes in muscle activity, bite force and salivary cortisol in children with bruxism after the application of low-level laser to accupoints...
August 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28782569/the-protective-effects-of-electro-acupuncture-in-thoracic-surgery-on-trauma-stressed-rats-involve-the-rostral-ventrolateral-medulla-and-supraoptic-nucleus
#9
Huan-Huan Zhang, Yi-Nan Tao, Mei-Yan Jiang, Jin Wang, Jun Chen, Chun-Mei Xia, Lin-Lin Shen, Meng-Ya Wang, Da-Nian Zhu
The present study was designed to explore whether the rostral ventrolateral medulla (RVLM) and supraoptic nucleus (SON) were involved in the protective effects of electro-acupuncture (EA) on cardiac function in thoracic surgery on trauma-stressed rats. The rats were randomly divided into a non-stressed group (Control), surgical trauma-stressed group (Trauma), and Neiguan EA applied on the surgical trauma-stressed group (Trauma+EA-PC 6). RVLM neuron discharge was observed by using an in vivo electrophysiological method, and micro-dialysis combining high-performance liquid chromatography with fluorometric detection (HPLC-FD) was used to assess expression of amino acids in the RVLM...
August 3, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28768251/a-randomized-controlled-trial-examining-the-effect-of-acupressure-on-agitation-and-salivary-cortisol-in-nursing-home-residents-with-dementia
#10
Rick Yiu Cho Kwan, Mason Chin Pang Leung, Claudia Kam Yuk Lai
BACKGROUND: Acupressure has been used to manage agitation in people with dementia because it is safe and inexpensive. However, its effect on agitation and at the biochemical level is uncertain. METHODS: This randomized controlled trial examined the effect of acupressure on agitation, as measured by the Cohen-Mansfield Agitation Inventory (CMAI); and on salivary cortisol, as measured at baseline (T0) and in the 3rd (T1), 5th (T2), and 8th (T3) weeks. There were 119 agitated residents with dementia randomized into 3 groups: acupressure (n = 39), sham (n = 41), and usual-care group (n = 39)...
July 29, 2017: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/28767271/effects-of-transcutaneous-electrical-acupoint-stimulation-on-motor-functions-and-self-care-ability-in-children-with-cerebral-palsy
#11
Bei Zhang, Yulan Zhu, Congyu Jiang, Ce Li, Yingying Li, Yulong Bai, Yi Wu
OBJECTIVES: To observe the effects of transcutaneous electrical acupoint stimulation (TEAS) in improving motor functions and self-care abilities in children with cerebral palsy in their early childhood. DESIGN: A preliminary, prospective, cohort study. SETTINGS/LOCATION: Multicenter. SUBJECTS: Children aged 2-6 years old. INTERVENTIONS: Twenty-three children were included in the study and randomly assigned to a control group ([CG] N = 11) or a therapeutic group ([TG] N = 12)...
August 2, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28762132/electro-acupuncture-at-governor-vessel-improves-neurological-function-in-rats-with-spinal-cord-injury
#12
Wen-Zhan Tu, Song-He Jiang, Li Zhang, Si-Si Li, Peng-Peng Gu, Rong He, Jie Hu, Li-Ping Gao, Qiang-San Sun
OBJECTIVE: To determine the effects of electro-acupuncture (EA) at Governor Vessel (GV) on the locomotor function in spinal cord injury (SCI) rats and explore the underlying mechanism. METHODS: Thirtytwo male Sprague-Dawley rats were randomly divided into four groups namely: the sham group (with sham operation); the untreated group (without treatment after spinal cord impact); the EA-1 group [EA applied at Baihui (GV 20) and Fengfu (GV 16) after spinal cord impact] and the EA-2 group [with EA applied at Dazhui (GV 14) and Mingmen (GV 4) after spinal cord impact]...
July 31, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28761425/electroacupuncture-regulates-the-stress-injury-repair-chain-of-events-after-cerebral-ischemia-reperfusion-injury
#13
Peng Shi, Lin-Lin Sun, Yi-Shuo Lee, Ya Tu
Inflammation after stroke is the main cause of cerebral ischemia/reperfusion injury. Cascading events after injury can lead to cell death. Heat shock protein 70 and other endogenous injury-signaling molecules are released by damaged cells, which can lead to systemic stress reactions. Protecting the brain through repair begins with the stress-injury-repair signaling chain. This study aimed to verify whether acupuncture acts through this chain to facilitate effective treatment of ischemic stroke. Rat models of cerebral ischemia/reperfusion injury were established by Zea Longa's method, and injury sites were identified by assessing neurological function, 2,3,5-triphenyltetrazolium chloride staining, and hematoxylin-eosin staining...
June 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28760342/induction-of-%C3%AE-6-and-%C3%AE-1-integrins-by-acupuncture-stimulation-in-rats
#14
Hwa Chul Shin, Ji-Yeun Park, Hee Don Lim, Uk Namgung
Acupuncture therapy is performed by applying the needle insertion at discrete cutaneous locations and used for the treatments of diverse symptoms and disorders. In order to elucidate mechanistic basis on how acupuncture stimulation (AS) produces therapeutic effects, it is primarily important to understand tissue responses locally at the acupuncture site (acupoint). Here, we investigated integrin protein as molecular target responding to and integrating AS. Signals of α6 and β1 integrins were clearly induced at zusanli acupoint 24 h after AS in areas of nuclear clusters around the needle track...
July 28, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28756309/activation-of-brain-glucose-metabolism-ameliorating-cognitive-impairment-in-app-ps1-transgenic-mice-by-electroacupuncture
#15
Weilin Liu, Peiyuan Zhuo, Long Li, Hao Jin, Bingbing Lin, Yingzheng Zhang, Shengxiang Liang, Jie Wu, Jia Huang, Zhifu Wang, Ruhui Lin, Lidian Chen, Jing Tao
An essential feature of Alzheimer's disease (AD) is implicated in brain energy metabolic impairment that is considered underlying pathogenesis of cognitive impairment. Therefore, therapeutic interventions to allay cognitive deficits that target energy metabolism may be an efficacy strategy in AD. In this study, we found that electroacupuncture (EA) at the DU20 acupoint obviously increased glucose metabolism in specific brain regions such as cortex, hippocampus, cingulate gyrus, basal forebrain septum, brain stem, and cerebellum in APP/PS1 transgenic mice by animal (18)F-Fluoro-2-deoxy-D-Glucose ((18)F-FDG)/positron emission tomography (PET) imaging, accompanied by cognitive improvements in the spatial reference learning and memory and memory flexibility and novel object recognition performances...
July 26, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28754994/-1-h-nmr-based-investigation-of-metabolic-response-to-electro-acupuncture-stimulation
#16
Caigui Lin, Zhiliang Wei, Kian-Kai Cheng, Jingjing Xu, Guiping Shen, Chang She, Huan Zhong, Xiaorong Chang, Jiyang Dong
Acupuncture is a traditional Chinese medicine therapy that has been found useful for treating various diseases. The treatments involve the insertion of fine needles at acupoints along specific meridians (meridian specificity). This study aims to investigate the metabolic basis of meridian specificity using proton nuclear magnetic resonance ((1)H NMR)-based metabolomics. Electro-acupuncture (EA) stimulations were performed at acupoints of either Stomach Meridian of Foot-Yangming (SMFY) or Gallbladder Meridian of Foot-Shaoyang (GMFS) in healthy male Sprague Dawley (SD) rats...
July 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28751169/differences-in-laser-doppler-indices-between-skin-surface-measurement-sites-in-subjects-with-diabetes
#17
Hsin Hsiu, Hsiao-Feng Hu, Hung-Chi Tsai
This study performed laser-Doppler flowmetry (LDF) measurements with the aim of identifying differences in diabetes-induced microcirculatory-blood-flow (MBF) responses between the following skin surface measurement sites: an acupoint around the wrist, an acupoint around the ankle, and a nearby nonacupoint around the ankle. The 67 study subjects were assigned to diabetic, prediabetic, and healthy groups according to the results of oral glucose tolerance tests. Beat-to-beat and spectral analyses were applied to the LDF waveform to obtain the foot delay time (FDT), the flow rise time (FRT), and the relative energy contributions (RECs) in five frequency bands...
July 25, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28744003/a-sensitive-acupuncture-needle-microsensor-for-real-time-monitoring-of-nitric-oxide-in-acupoints-of-rats
#18
Lina Tang, Yutao Li, Hui Xie, Qing Shu, Fan Yang, Yan-Ling Liu, Fengxia Liang, Hua Wang, Weihua Huang, Guo-Jun Zhang
This study reports an acupuncture needle modified with an iron-porphyrin functionalized graphene composite (FGPC) for real-time monitoring of nitric oxide (NO) release in acupoints of rats. A gold film was first deposited to the needle surface to enhance the conductivity. The FGPC was prepared via hydrothermal synthesis, and subsequently applied to the tip surface of acupuncture needle by electrochemical deposition method. The functionalized needle enabled a specific and sensitive detection of NO based on the favorably catalytic properties of iron-porphyrin and the excellent conductivity of graphene...
July 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28736590/is-electroacupuncture-treatment-more-effective-in-somatic-tinnitus-than-in-nonsomatic-tinnitus
#19
Wong-Kein Low, Mahalakshmi Shetty Rangabashyam, Shu Li Cui, Vishal Deepak Dsouza, Chun Suan Ong, Siaw Wei Teng, Hui Hua Li
Background: In recent years, evidence has been accumulating linking subjective tinnitus to the somatosensory system. Somatic tinnitus is defined as tinnitus in which forceful contractions of jaw and neck muscles modulate the psychoacoustic attributes of tinnitus, such as pitch and loudness. Being a somatosensory-based treatment modality, needling might well be more effective for treating somatic than nonsomatic tinnitus. Objective: The aim of this study was to compare the outcomes of electroacupuncture (EA) treatment between patients with somatic and nonsomatic tinnitus...
June 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/28717380/response-of-local-nitric-oxide-release-to-manual-acupuncture-and-electrical-heat-in-humans-effects-of-reinforcement-methods
#20
Sheng-Xing Ma, Paul C Lee, Thomas L Anderson, Xi-Yan Li, Isabelle Z Jiang
This study was to examine the influences of manual acupuncture (MA) and electrical heat corresponding to reinforcing methods on nitric oxide (NO) release over the skin regions in humans. A device with collecting solution was taped to the skin surface along pericardium (PC) or lung (LU) meridian. Acupuncture needles were gently inserted into PC 4 with reinforcing stimulation (low force/rate) for 20 minutes in the MA group. LU11 on the finger was heated (43-44°C) by electrical heat for 20 minutes. Biocapture was consecutively conducted for two 20-minute intervals during and after each treatment...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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