Keratconus

Objective: To investigate the diagnosis of normal cornea, subclinical keratoconus and keratoconus by artifical intelligence. Methods: Diagnostic study. From January 2016 to January 2019, who admitted to Tianjin Eye Hospital from 18 to 48 years old, with an average of (28.4±8.2) years of myopia patients in 2 018 cases. Two experienced ophthalmologists labeled keratoconus, subclinical keratconus and nomal cornea based on the topography. The data of 80% (1 615 cases) patients were randomly selected as the training set by computer random sampling method, and the data of 20% (403 cases) patients were used as the verification set...

This study was designed to evaluate the correlation between corneal biomechanical and morphological data in healthy eyes, eyes that underwent myopic photorefractive keratectomy (PRK), keratoconus affected eyes, and keratoconus affected eyes that underwent corneal collagen crosslinking (CCC). Complete clinical eye examination of all eyes was followed by tomographic (Pentacam, Oculus, Wetzlar, Germany) and biomechanical (Corvis ST, Oculus, Wetzlar, Germany) evaluation. Differences among Corvis ST (CST) parameters in the different groups have been performed...

In an era of scientific method, precision of nomenclature and an electronically accessible publication record, the early history of keratoconus still remains, in parts, as complex and perplexing as the disease itself. Historically, the disease has been somewhat confusingly referred to by several different terms, including hyperkeratosis, ochlodes, conical formed cornea, cornea conica, cornée conique, sugar loaf cornea, prolapses corneae, procidentia corneae, staphyloma transparent de la cornée, staphyloma pellucidum, staphyloma corneae totale conicum pellucidum, staphyloma diaphanum, keratconus and keratoconus...

PURPOSE: Keratoconus is a noninflammatory disease characterized by thining and ectasia of the central cornea. The etiology and pathogenesis of keratoconus remain unclear. We studied the composition of basement membranes (BM) in normal, scarred and keratconus corneas to find out possible changes specific for keratoconus. METHODS: Paraffin-embeded sections of normal, scarred and keratoconus corneas were immunostained with antibodys against type IV collagen, Fibronectin (Fn) and Laminin (Ln)...

BACKGROUND: "Vertical tilt" of the graft caused by incongruent cut angles, "horizontal torsion" caused by a asymmetric suturing and decentration of the wound seem to be the most important reasons for high and/or irregular postoperative astigmatism and deterioration of visual outcome after penetrating keratoplasty. We studied the time course of qualitative and quantitative topographic criteria after nonmechanical and mechanical trephination in correlation with visual outcome. PATIENTS AND METHODS: Fifty patients each (30 keratconus, 20 Fuchs' dystrophies) underwent nonmechanical trephination (excimer laser MEL60, Aesculap-Meditec, Heroldsberg) and mechanical motor-trephination in penetrating keratoplasty...