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https://www.readbyqxmd.com/read/27863618/from-the-editor-s-desk-december-2016
#1
Richard Moreau, Ramon Bataller, Thomas Berg, Jessica Zucman-Rossi, Rajiv Jalan
No abstract text is available yet for this article.
December 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27805917/caval-subtraction-2d-phase-contrast-mri-to-measure-total-liver-and-hepatic-arterial-blood-flow-proof-of-principle-correlation-with-portal-hypertension-severity-and-validation-in-patients-with-chronic-liver-disease
#2
Manil D Chouhan, Rajeshwar P Mookerjee, Alan Bainbridge, Shonit Punwani, Helen Jones, Nathan Davies, Simon Walker-Samuel, David Patch, Rajiv Jalan, Steve Halligan, Mark F Lythgoe, Stuart A Taylor
OBJECTIVES: Caval subtraction phase-contrast magnetic resonance imaging (PCMRI) noninvasive measurements of total liver blood flow (TLBF) and hepatic arterial (HA) flow have been validated in animal models and translated into normal volunteers, but not patients. This study aims to demonstrate its use in patients with liver cirrhosis, evaluate measurement consistency, correlate measurements with portal hypertension severity, and invasively validate TLBF measurements. MATERIALS AND METHODS: Local research ethics committee approval was obtained...
October 31, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/27736081/a-new-line-defect-in-ndtio3-perovskite
#3
Jong Seok Jeong, Mehmet Topsakal, Peng Xu, Bharat Jalan, Renata M Wentzcovitch, K Andre Mkhoyan
Perovskite oxides form an eclectic class of materials owing to their structural flexibility in accommodating cations of different sizes and valences. They host well known point and planar defects, but so far no line defect has been identified other than dislocations. Using analytical scanning transmission electron microscopy (STEM) and ab initio calculations we have detected and characterized the atomic and electronic structures of a novel line defect in NdTiO3 perovskite. It appears in STEM images as a perovskite cell rotated by 45 degrees...
October 13, 2016: Nano Letters
https://www.readbyqxmd.com/read/27730496/modification-in-csf-specific-gravity-in-acutely-decompensated-cirrhosis-and-acute-on-chronic-liver-failure-independent-of-encephalopathy-evidences-for-an-early-blood-csf-barrier-dysfunction-in-cirrhosis
#4
Nicolas Weiss, Matteo Rosselli, Sarah Mouri, Damien Galanaud, Louis Puybasset, Banwari Agarwal, Dominique Thabut, Rajiv Jalan
Although hepatic encephalopathy (HE) on the background of acute on chronic liver failure (ACLF) is associated with high mortality rates, it is unknown whether this is due to increased blood-brain barrier permeability. Specific gravity of cerebrospinal fluid measured by CT is able to estimate blood-cerebrospinal fluid-barrier permeability. This study aimed to assess cerebrospinal fluid specific gravity in acutely decompensated cirrhosis and to compare it in patients with or without ACLF and with or without hepatic encephalopathy...
October 11, 2016: Metabolic Brain Disease
https://www.readbyqxmd.com/read/27713003/diacylglycerol-kinase-epsilon-suppresses-expression-of-p53-and-glycerol-kinase-in-mouse-embryo-fibroblasts
#5
Vincent So, Divyanshi Jalan, Mathieu Lemaire, Matthew K Topham, Grant M Hatch, Richard M Epand
The incorporation of glycerol into lipid was measured using SV40 transformed mouse embryo fibroblasts (MEFs) from either wild-type (WT) mice or from mice in which the epsilon isoform of diacylglycerol kinase (DGKε) was knocked out (DGKε(-/-)). We present an explanation for our finding that DGKε(-/-) MEFs exhibited greater uptake of (3)H-glycerol into the cell and a greater incorporation into lipids compared with their WT counterparts, with no change in the relative amounts of various lipids between the DGKε(-/-) and WT MEFs...
October 3, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27641780/from-the-editor-s-desk-october-2016
#6
Richard Moreau, Ramon Bataller, Thomas Berg, Jessica Zucman-Rossi, Rajiv Jalan
No abstract text is available yet for this article.
October 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27636866/effects-of-early-surgical-decompression-on-functional-and-histological-outcomes-after-severe-experimental-thoracic-spinal-cord-injury
#7
Devesh Jalan, Neginder Saini, Mohammad Zaidi, Alexandra Pallottie, Stella Elkabes, Robert F Heary
OBJECTIVE In acute traumatic brain injury, decompressive craniectomy is a common treatment that involves the removal of bone from the cranium to relieve intracranial pressure. The present study investigated whether neurological function following a severe spinal cord injury improves after utilizing either a durotomy to decompress the intradural space and/or a duraplasty to maintain proper flow of cerebrospinal fluid. METHODS Sixty-four adult female rats (n = 64) were randomly assigned to receive either a 3- or 5-level decompressive laminectomy (Groups A and B), laminectomy + durotomy (Groups C and D), or laminectomy + duraplasty with graft (Group E and F) at 24 hours following a severe thoracic contusion injury (200 kilodynes)...
September 16, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27636487/predictive-control-over-charge-density-in-the-two-dimensional-electron-gas-at-the-polar-nonpolar-ndtio_-3-srtio_-3-interface
#8
Peng Xu, Yilikal Ayino, Christopher Cheng, Vlad S Pribiag, Ryan B Comes, Peter V Sushko, Scott A Chambers, Bharat Jalan
Through systematic control of the Nd concentration, we show that the carrier density of the two-dimensional electron gas (2DEG) in SrTiO_{3}/NdTiO_{3}/SrTiO_{3}(001) can be modulated over a wide range. We also demonstrate that the NdTiO_{3} in heterojunctions without a SrTiO_{3} cap is degraded by oxygen absorption from air, resulting in the immobilization of donor electrons that could otherwise contribute to the 2DEG. This system is, thus, an ideal model to understand and control the insulator-to-metal transition in a 2DEG based on both environmental conditions and film-growth processing parameters...
September 2, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27599825/from-the-editor-s-desk-november-2016
#9
Richard Moreau, Ramon Bataller, Thomas Berg, Jessica Zucman-Rossi, Rajiv Jalan
No abstract text is available yet for this article.
November 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27588678/novel-approaches-and-therapeutics-in-acute-on-chronic-liver-failure
#10
Rajiv Jalan
No abstract text is available yet for this article.
September 2, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/27562800/the-effect-of-temperature-exposure-during-shipment-on-a-commercially-available-demineralized-bone-matrix-putty
#11
Mark Schallenberger, Helena Lovick, Jalane Locke, Todd Meyer, Gregory Juda
During August and September of 2013, temperature data loggers were shipped to and from an AATB accredited and FDA registered allograft tissue processing facility in Belgrade, MT (Bacterin International, Inc.) to five warm climate cities (Dallas, TX, El Paso, TX, New Orleans, LA, Phoenix, AZ, and Tampa, FL). Shipping data acquired from 72 independent shipments were analyzed to generate an assessment of temperature exposure, shipment times, and shipping event durations experienced during routine distribution...
August 25, 2016: Cell and Tissue Banking
https://www.readbyqxmd.com/read/27430428/from-the-editor-s-desk-august-2016
#12
Richard Moreau, Ramon Bataller, Thomas Berg, Jessica Zucman-Rossi, Rajiv Jalan
No abstract text is available yet for this article.
August 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27422752/plasma-copeptin-as-biomarker-of-disease-progression-and-prognosis-in-cirrhosis
#13
Elsa Solà, Annarein J C Kerbert, Hein W Verspaget, Rebeca Moreira, Elisa Pose, Pablo Ruiz, Raquel Cela, Manuel Morales-Ruiz, Eva López, Isabel Graupera, Cristina Solé, Patricia Huelin, Alex Amorós Navarro, Xavier Ariza, Rajiv Jalan, Núria Fabrellas, Daniel Benten, Gloria de Prada, François Durand, Wladimiro Jimenez, Johan J van der Reijden, Javier Fernandez, Bart van Hoek, Minneke J Coenraad, Pere Ginès
BACKGROUND & AIMS: Research on vasopressin (AVP) in cirrhosis and its role in the assessment of prognosis has been hindered by the difficulty of measuring AVP levels accurately. Copeptin, a 39-aminoacid glycopeptide, is released from the neurohypophysis together with AVP. Copeptin could have a role as biomarker of prognosis in cirrhosis as it may reflect circulatory dysfunction. The aim of this study is to investigate the role of copeptin as biomarker of disease progression and prognosis in cirrhosis...
July 12, 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27401547/from-the-editor-s-desk%C3%A2-from-the-editor-s-desk-september-2016
#14
Richard Moreau, Ramon Bataller, Thomas Berg, Jessica Zucman-Rossi, Rajiv Jalan
No abstract text is available yet for this article.
September 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27317887/from-the-editor-s-desk-july-2016
#15
Richard Moreau, Ramon Bataller, Thomas Berg, Jessica Zucman-Rossi, Rajiv Jalan
No abstract text is available yet for this article.
July 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#16
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27277335/acute-on-chronic-liver-failure-in-cirrhosis
#17
Vicente Arroyo, Richard Moreau, Patrick S Kamath, Rajiv Jalan, Pere Ginès, Frederik Nevens, Javier Fernández, Uyen To, Guadalupe García-Tsao, Bernd Schnabl
The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and North America, the term is generally applied according to the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) Consortium guidelines, which defines this condition as a syndrome that develops in patients with cirrhosis and is characterized by acute decompensation, organ failure and high short-term mortality. One-third of patients who are hospitalized for acute decompensation present with ACLF at admission or develop the syndrome during hospitalization...
2016: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/27241199/corrigendum-to-management-of-the-critically-ill-patients-with-cirrhosis-a-multidisciplinary-perspective
#18
Mitra K Nadim, Francois Durand, John A Kellum, Josh Levitsky, Jacqueline G O'Leary, Constantine J Karvellas, Jasmohan S Bajaj, Andrew Davenport, Rajiv Jalan, Paolo Angeli, Stephen H Caldwell, Javier Fernández, Claire Francoz, Guadalupe Garcia-Tsao, Pere Ginès, Michael G Ison, David J Kramer, Ravindra L Mehta, Richard Moreau, David Mulligan, Jody C Olson, Elizabeth A Pomfret, Marco Senzolo, Randolph H Steadman, Ram M Subramanian, Jean-Louis Vincent, Yuri S Genyk
No abstract text is available yet for this article.
May 27, 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27205897/not-all-mice-are-the-same-standardization-of-animal-research-data-presentation
#19
M Bishr Omary, David E Cohen, Emad M El-Omar, Rajiv Jalan, Malcolm J Low, Michael H Nathanson, Richard M Peek, Jerrold R Turner
No abstract text is available yet for this article.
June 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/27198047/from-the-editor-s-desk-june-2016
#20
Richard Moreau, Ramon Bataller, Thomas Berg, Jessica Zucman-Rossi, Rajiv Jalan
TREATED HEPATITIS C VIRUS (HCV) CIRRHOTIC PATIENTS CAN HAVE NORMAL LIFE EXPECTANCY: The fact that a sustained virologic response (SVR) is associated with an improved outcome of chronic HCV infection, has been demonstrated in several studies by comparing patients with and without SVR. The study by Bruno et al., however, is the first to demonstrate that patients with compensated cirrhosis who achieve SVR will have a life expectancy similar to that of the sex- and age-matched general population. Patients were enrolled in historical prospective cohort studies from tertiary referral centers from Northern and Southern Italy...
June 2016: Journal of Hepatology
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