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GLM or (general linear model)

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https://www.readbyqxmd.com/read/28922422/psychological-effects-of-the-intensified-follow-up-of-the-ceawatch-trial-after-treatment-for-colorectal-cancer
#1
Zhuozhao Zhan, Charlotte J Verberne, Edwin R van den Heuvel, Irene Grossmann, Adelita V Ranchor, Theo Wiggers, Geertruida H de Bock
BACKGROUND: The aim of the study was to evaluate psychological effects of the state-of-art intensified follow-up protocol for colorectal cancer patients in the CEAwatch trial. METHOD: At two time points during the CEAwatch trial questionnaires regarding patients' attitude towards follow-up, patients' psychological functioning and patients' experiences and expectations were sent to participants by post. Linear mixed models were fitted to assess the influences and secular trends of the intensified follow-up on patients' attitude towards follow-up and psychological functioning...
2017: PloS One
https://www.readbyqxmd.com/read/28922296/trajectories-of-glycemic-change-in-a-national-cohort-of-adults-with-previously-controlled-type-2-diabetes
#2
Rozalina G McCoy, Che Ngufor, Holly K Van Houten, Brian Caffo, Nilay D Shah
BACKGROUND: Individualized diabetes management would benefit from prospectively identifying well-controlled patients at risk of losing glycemic control. OBJECTIVES: To identify patterns of hemoglobin A1c (HbA1c) change among patients with stable controlled diabetes. RESEARCH DESIGN: Cohort study using OptumLabs Data Warehouse, 2001-2013. We develop and apply a machine learning framework that uses a Bayesian estimation of the mixture of generalized linear mixed effect models to discover glycemic trajectories, and a random forest feature contribution method to identify patient characteristics predictive of their future glycemic trajectories...
September 15, 2017: Medical Care
https://www.readbyqxmd.com/read/28922020/seasonal-and-weather-variation-of-sleep-and-physical-activity-in-12-14-year-old-children
#3
Mirja Quante, Rui Wang, Jia Weng, Emily R Kaplan, Michael Rueschman, Elsie M Taveras, Sheryl L Rifas-Shiman, Matthew W Gillman, Susan Redline
BACKGROUND: Understanding variation in physical activity (PA) and sleep is necessary to develop novel intervention strategies targeting adolescents' health behaviors. We examined the extent to which PA and sleep vary by aspects of the physical environment. PARTICIPANTS: We performed a cross-sectional analysis of 669 adolescents in the Project Viva cohort. METHODS: We estimated total PA, sleep duration, sleep efficiency and sleep midpoint timing from wrist accelerometers...
September 18, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28921778/alcohol-e-help-study-protocol-for-a-web-based-self-help-program-to-reduce-alcohol-use-in-adults-with-drinking-patterns-considered-harmful-hazardous-or-suggestive-of-dependence-in-middle-income-countries
#4
Michael P Schaub, Marcela Tiburcio, Nora Martinez, Atul Ambekar, Yatan Pal Singh Balhara, Andreas Wenger, André Luiz Monezi Andrade, Dzianis Padruchny, Sergey Osipchik, Elise Gehring, Vladimir Poznyak, Dag Rekve, Maria Lucia Oliveira Souza-Formigoni
BACKGROUND AND AIMS: Given the scarcity of alcohol prevention and alcohol use disorder treatments in many low and middle-income countries, the World Health Organization launched an e-health portal on alcohol and health that includes a Web-based self-help program. This paper presents the protocol for a multicenter randomised controlled trial (RCT) to test the efficacy of the Internet-based self-help intervention to reduce alcohol use. DESIGN: Two-arm RCT with follow-up 6 months after randomisation...
September 17, 2017: Addiction
https://www.readbyqxmd.com/read/28920408/characterization-of-gene-expression-and-genetic-variation-of-horse-errfi1-in-thoroughbreds
#5
Jae-Young Choi, Hyun-Jun Jang, Jeong-Woong Park, Jae-Don Oh, Donghyun Shin, Nam Young Kim, Jin Hyeog Oh, Ki-Duk Song, Byung-Wook Cho
Objective: This study aimed to test the expression patterns of ERBB receptor feedback inhibitor 1 (ERRFI1) before and after exercise and the association of non-synonymous single-nucleotide polymorphisms (nsSNPs) of horse ERRFI1 with racing traits in Thoroughbreds. Methods: We performed bioinformatics and gene expression analyses for horse ERRFI1. Transcription factor (TF) binding sites in the 5'-regulatory region of this gene were identified through PROMO. A general linear model (GLM) was used to detect the association between the nsSNP (LOC42830758 A to G) and race performance...
September 18, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28919795/type-2-diabetes-in-vietnam-a-cross-sectional-prevalence-based-cost-of-illness-study
#6
Nguyen Tu Dang Le, Luyen Dinh Pham, Trung Quang Vo
BACKGROUND: According to the International Diabetes Federation, total global health care expenditures for diabetes tripled between 2003 and 2013 because of increases in the number of people with diabetes as well as in the average expenditures per patient. This study aims to provide accurate and timely information about the economic impacts of type 2 diabetes mellitus (T2DM) in Vietnam. METHOD: The cost-of-illness estimates followed a prospective, prevalence-based approach from the societal perspective of T2DM with 392 selected diabetic patients who received treatment from a public hospital in Ho Chi Minh City, Vietnam, during the 2016 fiscal year...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/28919221/ten-year-projections-for-us-residency-positions-will-there-be-enough-positions-to-accommodate-the-growing-number-of-u-s-medical-school-graduates
#7
Sarah Hayek, Samantha Lane, Marcus Fluck, Marie Hunsinger, Joseph Blansfield, Mohsen Shabahang
OBJECTIVE: Recently, a multitude of new U.S. medical schools have been established and existing medical schools have expanded their enrollments. The National Residency Match Program (NRMP) reports that in 2016 there were 23,339 categorical residency positions offered in the match and 26,836 overall applicants with 17,789 (66.29%) of the total candidates being U.S. allopathic graduates. In view of the rapid growth of medical school graduates, the aim of this study is to determine if current trends suggest a shortage of residency positions within the next ten years...
September 14, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28919191/benefits-of-the-restorative-exercise-and-strength-training-for-operational-resilience-and-excellence-yoga-program-for-chronic-lower-back-pain-in-service-members-a-pilot-randomized-control-trial
#8
Krista Beth Highland, Audrey Schoomaker, Winifred Rojas, Josh Suen, Ambareen Ahmed, Zhiwei Zhang, Sarah Fink Carlin, Christian Calilung, Michael Kent, Chester Buckenmaier
OBJECTIVE: To examine the feasibility and preliminary effectiveness of an individualized yoga program. DESIGN: Pilot randomized control trial. SETTING: Military medical center. PARTICIPANTS: Patients (N=68) with chronic LBP. INTERVENTIONS: Restorative Exercise and Strength Training for Operational Resilience and Excellence (RESTORE) program (9-12 individual yoga sessions) or treatment-as-usual (control) for 8-week period...
September 14, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28918764/fragile-environment-seasonality-and-maternal-and-childhood-undernutrition-in-bangladesh
#9
Masuda Mohsena, Mahabub Hossain, Barnali Chakraborty, Abdul Bayes, A N Mahfuzur Rahman
This study assessed whether agricultural and household incomes were the same across different agro-ecological environments in Bangladesh. An in-depth analysis of the effect of unfavourable ecologies on maternal and child malnutrition was carried out. Data were from a longitudinal data set comprising a nationally representative data sample collected in 2014 and the Food Security Nutrition Surveillance Project (FSNSP) conducted in 2011 and 2012. Anthropometric indices were used to assess the nutritional status of mothers and under-five children...
September 18, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28917614/age-and-fecundability-in-a-north-american-preconception-cohort-study
#10
Amelia K Wesselink, Kenneth J Rothman, Elizabeth E Hatch, Ellen M Mikkelsen, Henrik T Sørensen, Lauren A Wise
BACKGROUND: There is a well-documented decline in fertility treatment success with increasing female age; however, there are few preconception cohort studies examining female age and natural fertility. In addition, data on male age and fertility is inconsistent. Given the increasing number of couples attempting conception at older ages, a more detailed characterization of age-related fecundability in the general population is of great clinical utility. OBJECTIVE: To examine the association between female and male age with fecundability...
September 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28917612/thyroid-stimulating-hormone-anti-thyroid-antibodies-and-pregnancy-outcomes
#11
Torie C Plowden, Enrique F Schisterman, Lindsey A Sjaarda, Neil J Perkins, Robert Silver, Rose Radin, Keewan Kim, Noya Galai, Alan H DeCherney, Sunni L Mumford
BACKGROUND: Overt thyroid dysfunction has been associated with adverse obstetrical outcomes. However, less is known regarding subclinical hypothyroidism or thyroid autoimmunity and their relationship to pregnancy complications. OBJECTIVE: To examine the association between pre-pregnancy anti-thyroid antibodies and subclinical hypothyroidism and preterm delivery (PTD), gestational diabetes (GDM), and preeclampsia. STUDY DESIGN: Secondary analysis of a prospective cohort of 18-40 year old women with 1-2 prior pregnancy losses (n=1193) participating in a multi-center randomized, placebo-controlled trial of low-dose aspirin...
September 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28917245/a-single-nucleotide-polymorphism-in-transferrin-is-associated-with-soluble-transferrin-receptor-in-chinese-adolescents
#12
Wei Piao, Li Wang, Ting Zhang, Zhen Wang, Shaofang Shangguan, Jing Sun, Junsheng Huo
BACKGROUND AND OBJECTIVES: Associations between genetic variants in the hepcidin regulation pathway and iron status have been reported in previous studies. Most of these studies were conducted in populations of European descent and relatively few studies have been conducted in Chinese populations. In this study, we evaluated associations between single-nucleotide polymorphisms (SNPs) in the hepcidin regulation pathway, serum ferritin (SF) and soluble transferrin receptor (sTfR) in Chinese adolescents...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28917129/residential-road-traffic-noise-and-general-mental-health-in-youth-the-role-of-noise-annoyance-neighborhood-restorative-quality-physical-activity-and-social-cohesion-as-potential-mediators
#13
Angel Dzhambov, Boris Tilov, Iana Markevych, Donka Dimitrova
Given the ubiquitous nature of both noise pollution and mental disorders, their alleged association has not escaped the spotlight of public health research. The effect of traffic noise on mental health is probably mediated by other factors, which have not been elucidated sufficiently. Herein, we aimed to disentangle the pathways linking road traffic noise to general mental health in Bulgarian youth, with a focus on several candidate mediators - noise annoyance, perceived restorative quality of the living environment, physical activity, and neighborhood social cohesion...
September 13, 2017: Environment International
https://www.readbyqxmd.com/read/28917056/on-the-ambiguity-of-interaction-and-nonlinear-main-effects-in-a-regime-of-dependent-covariates
#14
Hannes Matuschek, Reinhold Kliegl
The analysis of large experimental datasets frequently reveals significant interactions that are difficult to interpret within the theoretical framework guiding the research. Some of these interactions actually arise from the presence of unspecified nonlinear main effects and statistically dependent covariates in the statistical model. Importantly, such nonlinear main effects may be compatible (or, at least, not incompatible) with the current theoretical framework. In the present literature, this issue has only been studied in terms of correlated (linearly dependent) covariates...
September 15, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28916916/investigating-baseline-red-meat-slaughter-operator-capacity-and-directions-for-development-in-lao-pdr
#15
Joanne C Thomas, James R Young, Kathrin Schemann, Phaivanh Chankhamthong, Syseng Khounsy, Sonevilay Nampanya, Peter A Windsor, Russell D Bush
A study of operator knowledge, attitudes and practices (KAP) in red meat slaughter premise operations in northern Laos was conducted and compared with international best practice, to inform future industry development. The survey interviewed 68 (of 94 possible participants) employees from all ten commercial slaughter premises in six districts in three northern Laos provinces. This was supported by observations of slaughter premises, processes and the conduct of personnel. Descriptive analysis and linear regression modelling identified significant KAP predictor factors, and a gap analysis supported or rejected inferences from the generally low KAP scores for human and animal health, animal welfare, good manufacturing practices (GMP), work conditions and economics...
September 15, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28916045/evaluation-of-fluorogenic-substrates-for-ni-co-ldhs-peroxidase-mimic-and-application-for-determination-of-inhibitory-effects-of-antioxidant
#16
Li Su, Xinai Yu, Yexi Cai, Puhua Kang, Wenjie Qin, Wenpei Dong, Guojiang Mao, Suling Feng
Nanomaterial-based peroxidase-mimetics are an emerging research field that promises to produce alternatives to horseradish peroxidase for a variety of applications. Generally, some peroxidase-mimetics substrates are used in acidic condition (pH ≤ 7). Then, it is necessary to screen some peroxidase-mimetics substrates suitable for basic condition because that some peroxidase-mimetics leached ions in acidic solution. In this paper, using Ni/Co layered double hydroxides (LDHs) as a nano-peroxidase mimic model, we evaluated three fluorogenic substrates suitable for basic condition though experimental conditions, reaction kinetic and glucose detection assay...
September 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28915844/financial-incentives-and-purchase-restrictions-in-a-food-benefit-program-affect-the-types-of-foods-and-beverages-purchased-results-from-a-randomized-trial
#17
Simone A French, Sarah A Rydell, Nathan R Mitchell, J Michael Oakes, Brian Elbel, Lisa Harnack
BACKGROUND: This research evaluated the effects of financial incentives and purchase restrictions on food purchasing in a food benefit program for low income people. METHODS: Participants (n=279) were randomized to groups: 1) Incentive- 30% financial incentive for fruits and vegetables purchased with food benefits; 2) Restriction- no purchase of sugar-sweetened beverages, sweet baked goods, or candies with food benefits; 3) Incentive plus Restriction; or 4) Control- no incentive or restrictions...
September 16, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28915730/adsorption-and-diffusion-of-fluids-in-defective-carbon-nanotubes-insights-from-molecular-simulations
#18
Benjamin J Bucior, German V Kolmakov, JoAnna M Male, Jinchen Liu, De-Li Chen, Prashant Kumar, J Karl Johnson
Single-walled carbon nanotubes (SWNTs) have been shown from both simulations and experiments to have remarkably low resistance to gas and liquid transport. This has been attributed to the remarkably smooth interior surface of pristine SWNTs. However, real SWNTs are known to have various defects that depend on the synthesis method and procedure used to activate the SWNTs. In this paper we study adsorption and transport properties of atomic and molecular gases and fluids in SWNTs having vacancy point defects...
September 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28915511/children-s-comprehension-of-object-relative-sentences-it-s-extant-language-knowledge-that-matters-not-domain-general-working-memory
#19
Yazmin Ahmad Rusli, James W Montgomery
Purpose: The aim of this study was to determine whether extant language (lexical) knowledge or domain-general working memory is the better predictor of comprehension of object relative sentences for children with typical development. We hypothesized that extant language knowledge, not domain-general working memory, is the better predictor. Method: Fifty-three children (ages 9-11 years) completed a word-level verbal working-memory task, indexing extant language (lexical) knowledge; an analog nonverbal working-memory task, representing domain-general working memory; and a hybrid sentence comprehension task incorporating elements of both agent selection and cross-modal picture-priming paradigms...
September 15, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28915462/abundance-of-large-old-trees-in-wood-pastures-of-transylvania-romania
#20
Tibor Hartel, Jan Hanspach, Cosmin I Moga, Lucian Holban, Árpád Szapanyos, Réka Tamás, Csaba Hováth, Kinga-Olga Réti
Wood-pastures are special types of agroforestry systems that integrate trees with livestock grazing. Wood pastures can be hotspots for large old tree abundance and have exceptional natural values; but they are declining all over Europe. While presence of large old trees in wood-pastures can provide arguments for their maintenance, actual data on their distribution and abundance are sparse. Our study is the first to survey large old trees in Eastern Europe over such a large area. We surveyed 97 wood-pastures in Transylvania (Romania) in order to (i) provide a descriptive overview of the large old tree abundance; and (ii) to explore the environmental determinants of the abundance and persistence of large old trees in wood-pastures...
September 12, 2017: Science of the Total Environment
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