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https://www.readbyqxmd.com/read/27832811/farm-characteristics-and-management-routines-related-to-neonatal-porcine-diarrhoea-a-survey-among-swedish-piglet-producers
#1
Jenny Larsson, Nils Fall, Maria Lindberg, Magdalena Jacobson
BACKGROUND: In recent years reports from a number of countries, including Sweden, describe problems with diarrhoea in newborn piglets despite the use of previously effective preventive measures. This seemingly altered disease pattern of neonatal porcine diarrhoea (NPD) warrants investigations on the magnitude and manifestation of the problem. The aim of the present study was to investigate the herd-level prevalence of NPD in Sweden and to describe disease characteristics and intervention strategies used in affected herds...
November 10, 2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/27773474/knowledge-attitudes-and-practices-of-healthcare-providers-in-the-country-of-georgia-regarding-influenza-vaccinations-for-pregnant-women
#2
Mariam Dvalishvili, Darejan Mesxishvili, Maia Butsashvili, George Kamkamidze, Deborah McFarland, Robert A Bednarczyk
OBJECTIVE: To document knowledge, attitudes, and practices of Georgian obstetrician-gynecologists concerning influenza infection and vaccination during pregnancy. METHODS: We conducted a cross-sectional study of obstetrician-gynecologists in 8 cities in the country of Georgian, from June to July, 2015, using an anonymous, self-administered, written survey. Collected data included demographics; knowledge, attitudes, and practices related to influenza vaccination during pregnancy; perceptions of influenza infection in pregnancy; perceived barriers to influenza vaccination during pregnancy; and willingness to receive education about influenza infection and vaccination during pregnancy...
October 20, 2016: Vaccine
https://www.readbyqxmd.com/read/27742214/maternal-pertussis-and-influenza-immunization-coverage-and-attitude-of-health-care-workers-towards-these-recommendations-in-flanders-belgium
#3
Kirsten Maertens, Tessa Braeckman, Geert Top, Pierre Van Damme, Elke Leuridan
In Belgium, pertussis vaccination is recommended for all pregnant women in every pregnancy. Adults in close contact with young infants are equally advised to receive a pertussis containing booster dose. Maternal influenza vaccination is likewise recommended in Belgium in the second or third trimester of pregnancy, within the influenza season. A quantitative multicenter survey study has been performed between October 2014 and May 2015 in both postpartum women (N=823, response rate=89.2%) and health care workers (HCWs) (N=261) to assess the coverage of both vaccines during pregnancy along with the coverage of the pertussis cocoon strategy, and to evaluate the knowledge and recommending attitude of HCWs towards the maternal vaccination strategies and the cocoon strategy among surveyed women and HCWs...
October 11, 2016: Vaccine
https://www.readbyqxmd.com/read/27633910/strengthening-the-reporting-of-observational-studies-in-epidemiology-for-newborn-infection-strobe-ni-an-extension-of-the-strobe-statement-for-neonatal-infection-research
#4
REVIEW
Elizabeth J A Fitchett, Anna C Seale, Stefania Vergnano, Michael Sharland, Paul T Heath, Samir K Saha, Ramesh Agarwal, Adejumoke I Ayede, Zulfiqar A Bhutta, Robert Black, Kalifa Bojang, Harry Campbell, Simon Cousens, Gary L Darmstadt, Shabir A Madhi, Ajoke Sobanjo-Ter Meulen, Neena Modi, Janna Patterson, Shamim Qazi, Stephanie J Schrag, Barbara J Stoll, Stephen N Wall, Robinson D Wammanda, Joy E Lawn
Neonatal infections are estimated to account for a quarter of the 2·8 million annual neonatal deaths, as well as approximately 3% of all disability-adjusted life-years. Despite this burden, few data are available on incidence, aetiology, and outcomes, particularly regarding impairment. We aimed to develop guidelines for improved scientific reporting of observational neonatal infection studies, to increase comparability and to strengthen research in this area. This checklist, Strengthening the Reporting of Observational Studies in Epidemiology for Newborn Infection (STROBE- NI), is an extension of the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement...
October 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27603545/the-effects-of-influenza-vaccination-during-pregnancy-on-birth-outcomes-a-systematic-review-and-meta-analysis
#5
Marta C Nunes, Anushka R Aqil, Saad B Omer, Shabir A Madhi
Objective Numerous observational studies have evaluated the relationship between influenza vaccination during pregnancy and birth outcomes. The number of studies on this subject has increased, especially after the 2009 A/H1N1 pandemic (A/H1N1pdm09). This meta-analysis aims to determine the impact of maternal vaccination with either seasonal trivalent inactivated influenza vaccines (IIV) or A/H1N1pdm09 monovalent vaccines on the rates of preterm (PTB), small for gestational age (SGA), and low birth weight (LBW) births...
September 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27541370/the-safety-of-maternal-immunization
#6
Annette K Regan
Maternal vaccination offers the opportunity to protect pregnant women and their infants against potentially serious disease. As both pregnant women and their newborns are vulnerable to severe illness, the potential public health impact of mass maternal vaccination programs is remarkable. Several high-income countries recommend seasonal influenza and acellular pertussis vaccines, and many developing countries recommend immunization against tetanus during pregnancy. There is a significant amount of literature supporting the safety of vaccination during pregnancy...
August 19, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27530965/neonatal-invasive-pneumococcal-disease-new-zealand-experience-in-the-era-of-pneumococcal-vaccination
#7
Vicki Mount, Cameron Burton, Catherine Jackson, Helen Heffernan, Emma Best
BACKGROUND: Invasive pneumococcal disease (IPD) became a notifiable disease in New Zealand in 2008, and in the same year pneumococcal conjugate vaccine (PCV) was added to the childhood immunisation schedule. DESIGN: This was a retrospective study of IPD in infants aged <90 days reported to the national notifiable disease database, EpiSurv, from 1 January 2009 to 31 December 2013. All cases had Streptococcus pneumoniae isolated from a normally sterile site. MAIN OUTCOME MEASURES: IPD incidence was calculated for babies aged <90 and <30 days using the number of national IPD cases with a denominator of annual infant live births...
August 17, 2016: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27507412/-infection-prevention-in-newborns-through-maternal-vaccination-current-insights-and-developments
#8
N A T van der Maas, K van Aerde, L J Bont, M N Bekker, N Rots, H E de Melker
- In the first few months of life, newborns are vulnerable to infections.- Vaccination of the pregnant mother leads to transplacental antibody transfer, resulting in the best possible protection of the newborn.- Maternal vaccination has long been given for the prevention of tetanus in developing countries, and for the prevention of pertussis and influenza in developed countries, such as the United States, England and Belgium. These vaccinations give newborns good protection and, to date, no adverse effects are known for the foetus or the pregnancy...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27494630/influenza-immunization-during-pregnancy-benefits-for-mother-and-infant
#9
Isaac G Sakala, Yoshikazu Honda-Okubo, Johnson Fung, Nikolai Petrovsky
The serious consequences of influenza infection during pregnancy have been recognized for almost a century. In this article, we reviewed the evidence on the immunogenicity, safety and impact of maternal influenza immunization for both mother and child. After vaccination, pregnant women have similar protective titers of anti-influenza antibodies as non-pregnant women, demonstrating that pregnancy does not alter the trivalent inactivated influenza vaccine immune response. Studies from the United States, Europe and resource-constrained regions demonstrate that maternal vaccination is associated with increased anti-influenza antibody concentrations and protection in the newborn child as well as the immunized mother...
August 5, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27491687/neonatal-infections-case-definition-and-guidelines-for-data-collection-analysis-and-presentation-of-immunisation-safety-data
#10
Stefania Vergnano, Jim Buttery, Ben Cailes, Ravichandran Chandrasekaran, Elena Chiappini, Ebiere Clark, Clare Cutland, Solange Dourado de Andrade, Alejandra Esteves-Jaramillo, Javier Ruiz Guinazu, Chrissie Jones, Beate Kampmann, Jay King, Sonali Kochhar, Noni Macdonald, Alexandra Mangili, Reinaldo de Menezes Martins, César Velasco Muñoz, Michael Padula, Flor M Muñoz, James Oleske, Melvin Sanicas, Elizabeth Schlaudecker, Hans Spiegel, Maja Subelj, Lakshmi Sukumaran, Beckie N Tagbo, Karina A Top, Dat Tran, Paul T Heath
Maternal vaccination is an important area of research and requires appropriate and internationally comparable definitions and safety standards. The GAIA group, part of the Brighton Collaboration was created with the mandate of proposing standardised definitions applicable to maternal vaccine research. This study proposes international definitions for neonatal infections. The neonatal infections GAIA working group performed a literature review using Medline, EMBASE and the Cochrane collaboration and collected definitions in use in neonatal and public health networks...
December 1, 2016: Vaccine
https://www.readbyqxmd.com/read/27467322/-novel-approaches-to-control-the-rise-in-pertussis-cases
#11
J Machač, R Chlíbek, S Plíšek
UNLABELLED: Pertussis is a respiratory disease caused by the Gram-negative encapsulated bacterium Bordetella pertussis. Despite the high vaccination coverage rate and addition of new booster doses to the immunisation scheme (in response to the epidemiological situation), pertussis is on the rise not only in the Czech Republic but also in many other countries. The age groups at highest risk are infants and, to a lower extent, newborns who can get infected before receiving the first dose of vaccine and develop a severe course of the disease, often requiring admission to hospital...
2016: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/27449414/risk-of-preterm-or-small-for-gestational-age-birth-after-influenza-vaccination-during-pregnancy-caveats-when-conducting-retrospective-observational-studies
#12
Gabriela Vazquez-Benitez, Elyse O Kharbanda, Allison L Naleway, Heather Lipkind, Lakshmi Sukumaran, Natalie L McCarthy, Saad B Omer, Lei Qian, Stanley Xu, Michael L Jackson, Vinutha Vijayadev, Nicola P Klein, James D Nordin
Vaccines are increasingly targeted toward women of reproductive age, and vaccines to prevent influenza and pertussis are recommended during pregnancy. Prelicensure clinical trials typically have not included pregnant women, and when they are included, trials cannot detect rare events. Thus, postmarketing vaccine safety assessments are necessary. However, analysis of observational data requires detailed assessment of potential biases. Using data from 8 Vaccine Safety Datalink sites in the United States, we analyzed the association of monovalent H1N1 influenza vaccine (MIV) during pregnancy with preterm birth (<37 weeks) and small-for-gestational-age birth (birth weight < 10th percentile)...
August 1, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27349165/pertussis-control-strategies-a-consistent-approach-for-new-zealand-synopsis-of-ministry-of-health-workshop-april-2015
#13
Mary Nowlan, Nikki Turner, Tomasz Kiedrzynski, Diana Murfitt, Nina Sawicki
In the past decade, pertussis has made a global resurgence, driving reconsideration of national immunisation schedules and vaccine usage. A workshop held by the Ministry of Health in 2015 discussed New Zealand's pertussis disease control strategies. Data were presented from current research into vaccine safety during pregnancy and the effectiveness of the immunisation schedule in preventing pertussis throughout childhood. The greatest burden of disease and mortality remains in infants under 1 year of age, especially infants too young to be immunised, those of Māori and Pacific ethnicity, and those living in deprivation...
2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27317458/predictors-of-maternal-vaccination-in-the-united-states-an-integrative-review-of-the-literature
#14
REVIEW
Kristen L Myers
OBJECTIVES: The purpose of this literature review was to identify, analyze, and synthesize existing research related to patient, provider, and health system predictors of maternal vaccination in the United States, strategies used to increase maternal vaccination rates, and major theoretical frameworks used to guide maternal vaccination research. METHODS: A search for evidence was conducted in CINAHL, PubMed, PsychINFO, Cochrane Systematic Reviews, and Google Scholar...
July 25, 2016: Vaccine
https://www.readbyqxmd.com/read/27314823/effect-of-maternal-influenza-vaccination-on-hospitalization-for-respiratory-infections-in-newborns-a-retrospective-cohort-study
#15
Annette K Regan, Nicholas de Klerk, Hannah C Moore, Saad B Omer, Geoffrey Shellam, Paul V Effler
BACKGROUND: Infants are at increased risk of hospitalization for influenza. Although vaccinating women during pregnancy has been shown to reduce the incidence of influenza infection among newborns, population-based data are limited. METHODS: A population-based cohort of 31,028 mothers and singleton infants were included in the analysis. Hospitalizations with a principal diagnosis or additional diagnoses consistent with severe respiratory illness occurring during the 2012 and 2013 southern hemisphere influenza seasons were identified using a state-wide hospital discharge database...
October 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27255149/pertussis-antibody-concentrations-in-infants-born-prematurely-to-mothers-vaccinated-in-pregnancy
#16
Alison Kent, Shamez N Ladhani, Nick J Andrews, Mary Matheson, Anna England, Elizabeth Miller, Paul T Heath
BACKGROUND AND OBJECTIVES: Maternal antenatal pertussis-containing vaccination is recommended for the prevention of neonatal pertussis, but the ability of maternal vaccination to protect premature infants is unknown. We hypothesized that that infants born prematurely to antenatally vaccinated women would have higher pertussis antibody concentrations than those born to unvaccinated women. METHODS: Mothers had been offered a combined tetanus, diphtheria, 5-component acellular pertussis, inactivated polio vaccine from 28 weeks' gestation as part of their routine antenatal care...
July 2016: Pediatrics
https://www.readbyqxmd.com/read/27233120/maternal-immunization-optimizing-protection-for-the-mother-and-infant
#17
Alisa Kachikis, Janet A Englund
Immunizing the pregnant woman to protect both the mother and her infant from infection has been utilized increasingly over the last decade. New outbreaks of pandemic influenza and the resurgence of pertussis have resulted in policy changes and shifts in health authority recommendations for a number of vaccines aimed to protect both pregnant women and their infants in the first months of life. The ability of maternal immunoglobulin IgG antibodies to be transported readily across the healthy intact placenta depends on many different factors including gestational age in the pregnancy, nature and timing of the immunization and presence of maternal HIV or malaria infections...
July 5, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27216758/effectiveness-of-seasonal-trivalent-influenza-vaccination-against-hospital-attended-acute-respiratory-infections-in-pregnant-women-a-retrospective-cohort-study
#18
Annette K Regan, Nicholas de Klerk, Hannah C Moore, Saad B Omer, Geoffrey Shellam, Paul V Effler
BACKGROUND: Pregnant women are at risk of serious influenza infection. Although previous studies indicate maternal influenza vaccination can prevent hospitalisation in young infants, there is limited evidence of the effect in mothers. METHODS: A cohort of 34,701 pregnant women delivering between 1 April 2012 and 31 December 2013 was created using birth records. Principal diagnosis codes from hospital emergency department (ED) and inpatient records were used to identify episodes of acute respiratory illness (ARI) during the 2012 and 2013 southern hemisphere influenza seasons...
July 12, 2016: Vaccine
https://www.readbyqxmd.com/read/27213263/disease-burden-of-group-b-streptococcus-among-infants-in-sub-saharan-africa-a-systematic-literature-review-and-meta-analysis
#19
Anushua Sinha, Louise B Russell, Sara Tomczyk, Jennifer R Verani, Stephanie J Schrag, James A Berkley, Musa Mohammed, Betuel Sigauque, Sun-Young Kim
BACKGROUND: Group B streptococcus (GBS) is a leading neonatal sepsis pathogen globally. Investment in GBS disease prevention, such as maternal vaccination, requires evidence of disease burden, particularly in high infant mortality regions like sub-Saharan Africa. We aimed to provide such evidence by conducting a systematic literature review and meta-analysis to estimate maternal colonization proportion, GBS disease incidence and GBS serotype distribution. METHODS: MEDLINE, MEDLINE in process and Cochrane Library were searched for studies published during 1990-2014, pertaining to sub-Saharan Africa...
September 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27188951/cost-effectiveness-of-pertussis-vaccination-during-pregnancy-in-the-united-states
#20
Katherine E Atkins, Meagan C Fitzpatrick, Alison P Galvani, Jeffrey P Townsend
Vaccination against pertussis has reduced the disease burden dramatically, but the most severe cases and almost all fatalities occur in infants too young to be vaccinated. Recent epidemiologic evidence suggests that targeted vaccination of mothers during pregnancy can reduce pertussis incidence in their infants. To evaluate the cost-effectiveness of antepartum maternal vaccination in the United States, we created an age-stratified transmission model, incorporating empirical data on US contact patterns and explicitly modeling parent-infant exposure...
June 15, 2016: American Journal of Epidemiology
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