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sheehan syndrome

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https://www.readbyqxmd.com/read/28370163/development-of-a-22q11ds-psycho-educational-programme-exploration-of-the-views-concerns-and-educational-needs-of-parents-caring-for-children-or-adolescents-with-22q11ds-in-relation-to-mental-health-issues
#1
T Alugo, H Malone, A Sheehan, I Coyne, A Lawlor, F McNicholas
BACKGROUND: 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic condition with a broad phenotype. It is associated with a high prevalence of depression and anxiety during childhood and increased risk of schizophrenia in adulthood. Despite this, studies report that families may receive inadequate information of mental health (MH) risks at diagnosis. Therefore, this study investigated parents' experiences of caring for a child with 22q11DS, investigated their knowledge regarding the risk of MH problems and assessed the need for a psycho-educational programme...
March 30, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28367055/multicenter-open-label-exploratory-clinical-trial-with-rhodiola-rosea-extract-in-patients-suffering-from-burnout-symptoms
#2
Siegfried Kasper, Angelika Dienel
PURPOSE: This study is the first clinical trial aiming to explore the clinical outcomes in burnout patients treated with Rhodiola rosea. The reported capacity of R. rosea to strengthen the organism against stress and its good tolerability offer a promising approach in the treatment of stress-related burnout. The aim of the treatment was to increase stress resistance, thus addressing the source rather than the symptoms of the syndrome and preventing subsequent diseases associated with a history of burnout...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28272076/hypopituitarism-presenting-as-congestive-heart-failure
#3
S Giri, P Bansal, S Malik, R Bansal
Sheehan's syndrome (SS) develops as a result of ischemic pituitary necrosis due to severe postpartum hemorrhage and is characterized by various degrees of hypopituitarism. Although the occurrence of SS is now rare, it should still be considered in any woman with a history of peripartum hemorrhage who develops manifestations of pituitary hormone deficiency any time following the event. Appropriate hormone replacement therapy results in marked clinical improvement. We present an unusual case of SS in a young lady who continued to have normal menstruation after the index event, had two spontaneous pregnancies, and was diagnosed only 11 years later when she presented to us with acute heart failure...
March 3, 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/28262158/psychosis-as-a-late-manifestation-of-sheehan-s-syndrome
#4
Mukku Shiva Shanker Reddy, Abhinav Nahar, Harish Thippeswamy, Chaturvedi Santosh Kumar
Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum haemorrhage. It is one of the most common causes of hypopituitarism in underdeveloped or developing countries. Characteristic manifestations include failure to lactate or to resume menses, genital and axillary hair loss, asthenia and weakness, fine wrinkles around the eyes and lips, signs of premature aging, dry skin, hypopigmentation and other evidence of hypopituitarism. Uncommonly it can present with psychosis. There are only few case reports of psychoses in patients with Sheehan's syndrome...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28192732/reproductive-decisions-after-the-diagnosis-of-amniotic-fluid-embolism
#5
Amirhossein Moaddab, Miranda Klassen, Cynthia D Priester, Elvira H Munoz, Michael A Belfort, Steven L Clark, Gary A Dildy
OBJECTIVE: This study aims to describe the subsequent reproductive outcomes in women who either correctly or incorrectly were diagnosed with amniotic fluid embolism (AFE). STUDY DESIGN: Medical records were obtained, abstracted and reviewed by authors with extensive experience in critical care obstetrics. Telephone interviews of all survivors were conducted to determine obstetrical and contraceptive history. A subgroup underwent further telephone interview to address subsequent reproductive decisions...
January 23, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28129900/-atypical-and-rare-cardiac-revelation-about-sheehan-s-syndrome-a-report-of-three-cases
#6
N Bouznad, G El Mghari, M El Hattaoui, N El Ansari
Sheehan syndrome is a potentially serious complication in the postpartum period corresponding to ischemic necrosis of the anterior pituitary related to postpartum haemorrhage. We report three original observations showing an unusual mode of revelation of this syndrome. The first observation is that of a 46-year-old patient admitted initially to resuscitation for a recovered cardiorespiratory arrest, severe hypoglycemia and profound hyponatremia. The second is that of a 45-year-old patient, admitted for recurrent cardiac tamponade after pericardial and pleural puncture and pericardial drainage; clinical survey found signs of slight panhypopituitarism...
January 24, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/28004764/sheehan-syndrome
#7
Züleyha Karaca, Bashir A Laway, Hatice S Dokmetas, Hulusi Atmaca, Fahrettin Kelestimur
Sheehan syndrome or postpartum hypopituitarism is a condition characterized by hypopituitarism due to necrosis of the pituitary gland. The initial insult is caused by massive postpartum haemorrhage (PPH), leading to impaired blood supply to the pituitary gland, which has become enlarged during pregnancy. Small sella turcica size, vasospasms (caused by PPH) and/or thrombosis (associated with pregnancy or coagulation disorders) are predisposing factors; autoimmunity might be involved in the progressive worsening of pituitary functions...
December 22, 2016: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28004658/sheehan-syndrome
#8
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
December 22, 2016: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/27896263/complete-vaginal-outlet-stenosis-in-a-patient-with-sheehan-s-syndrome
#9
Minji Choo, Hana Park, Kyong Wook Yi
We present a case of complete vaginal stenosis in a woman diagnosed with Sheehan's syndrome. The patient delivered at full-term 5 months prior, and experienced massive postpartum bleeding at that time. During evaluation of persistent amenorrhea, we found that her vaginal orifice was completely adhesive and obstructed. Prior to corrective surgery, we managed the patient with an oral contraceptive to induce uterine bleeding into the vaginal outflow tract. After three cycles of an oral contraceptive, we could confirm that there was no stenotic lesion in the vaginal cavity as a hematocolpos was created...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27867901/sheehan-s-syndrome-in-two-generations
#10
Bashir Ahmad Laway, Mahroosa Ramzan, Shahnaz Ahmad Mir
No abstract text is available yet for this article.
November 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27854159/sheehan-s-syndrome-and-sickle-cell-disease-the-story-of-natasha
#11
Barbara A Wilson, Anita Rose, Gerhard Florschutz
Sheehan's syndrome (SS) is one of the pituitary disorders caused by severe blood loss during childbirth leading to necrosis of the pituitary gland. Diagnosis is made following severe haemorrhage, failure to produce milk and failure to menstruate. Rare in countries with good obstetric care, SS is still frequent in those countries with poor healthcare services. The majority of papers published on SS do not mention psychological or neuropsychological sequelae. Of those that do, mood disorders are sometimes reported and occasionally cognitive problems are noted, typically attention, memory or executive deficits...
November 17, 2016: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/27831835/imaging-of-neurologic-conditions-in-pregnant-patients
#12
Sangam Kanekar, Shante Bennett
A number of physiologic, hormonal, immunologic, and hemodynamic changes take place in the maternal body during pregnancy. The majority of these changes are essential for maintaining the normal course of pregnancy. However, these changes may also cause acute or chronic conditions that affect various biologic systems in the mother. In addition, conditions of the central and peripheral nervous systems can cause a variety of neurologic symptoms and complications. Neurologic signs and symptoms in pregnant and postpartum women may be due to the exacerbation of a preexisting medical condition, the initial manifestation of a primary central nervous system-related problem, or a neurologic problem unique to pregnancy and the postpartum period...
November 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27789188/efficacy-and-safety-of-the-glycine-transporter-type-1-inhibitor-amg-747-for-the-treatment-of-negative-symptoms-associated-with-schizophrenia
#13
Eduardo Dunayevich, Robert W Buchanan, Chao-Yin Chen, Jun Yang, Jon Nilsen, Julie M Dietrich, Hong Sun, Stephen Marder
OBJECTIVE: To determine the safety and efficacy of AMG 747, an oral inhibitor of glycine transporter type-1 (GlyT1), as an add-on to antipsychotic therapy in clinically stable people with schizophrenia with enduring negative symptoms. METHOD: Analysis of pooled data from two phase 2 studies. Adults diagnosed with schizophrenia stabilized on antipsychotic medication randomized (2:2:2:3) to orally receive daily AMG 747 (5mg, 15mg, or 40mg) or placebo. Primary endpoint was Negative Symptom Assessment (NSA)-16 total score change from baseline to week 12...
October 24, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27780154/maternal-and-neonatal-outcomes-following-expectant-management-of-preterm-prelabour-rupture-of-membranes-before-viability
#14
Winnie Huiyan Sim, Edward Araujo Júnior, Fabricio Da Silva Costa, Penelope Marie Sheehan
AIM: To assess the contemporary maternal and neonatal outcomes following expectant management of preterm premature rupture of membranes (PPROM) prior to 24 weeks' gestation and to identify prognostic indicators of this morbid presentation. METHODS: We performed a systematic review in the Pubmed and EMBASE databases to identify the primary (perinatal mortality, severe neonatal morbidity and serious maternal morbidity) and secondary (neonatal survival and morbidity) outcomes following expectant management of previable PPROM...
January 1, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27734221/educational-and-psychosocial-support-needs-in-lynch-syndrome-implementation-and-assessment-of-an-educational-workshop-and-support-group
#15
Marina J Corines, Jada G Hamilton, Emily Glogowski, Chris A Anrig, Rachael Goldberg, Kate Niehaus, Erin Salo-Mullen, Megan Harlan, Margaret R Sheehan, Magan Trottier, Asad Ahsraf, Christina Tran, Lauren Jacobs, Rohini Rau-Murthy, Anne G Lincoln, Mark E Robson, Jose G Guillem, Arnold J Markowitz, Kenneth Offit, Zsofia K Stadler
Few reports of educational and counseling support resources exist for Lynch syndrome (LS), a disorder requiring multi-organ cancer screening and specialized medical care throughout adult life. Here we describe the development and efficacy of two resources designed to address this need, the Memorial Sloan Kettering Cancer Center Clinical Genetics Service annual Lynch Syndrome Educational Workshop (LSEW), and a quarterly Lynch Syndrome Patient Advocacy Network (LSPAN) support group. The LSEW and LSPAN were implemented beginning in 2012...
April 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/27728203/recurrent-hypoglycemia-and-hyponatremia-an-unusual-presentation-of-sheehan-s-syndrome
#16
Abhimanyu Uppal
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728175/delayed-presentation-of-sheehans-syndrome-a-case-report
#17
Griger Cherry Williams, V A Kothiwale
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27727691/sheehan-syndrome-presenting-as-pancytopenia-divendu-bhushan
#18
Divendu Bhushan
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27636931/-evaluation-of-the-therapeutic-efficacy-and-safety-of-the-selective-anxiolytic-afobazole-in-generalized-anxiety-disorder-and-adjustment-disorders-results-of-a-multicenter-randomized-comparative-study-of-diazepam
#19
RANDOMIZED CONTROLLED TRIAL
T S Syunyakov, G G Neznamov
AIM: to summarize the previously published results of a multicenter randomized clinical research phase III study trial of afobazole (INN: fabomotizole) versus diazepam in the treatment of patients with generalized anxiety disorder (GAD) and adjustment disorders (AD). SUBJECTS AND METHODS: Five investigating centers included 150 patients aged 18 to 60 years (60 patients with GAD and 90 with AD) a simple structure of anxiety disorders without concurrent mental, neurological or somatic disorders...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27425780/genetic-expressions-of-thrombophilic-factors-in-patients-with-sheehan-s-syndrome
#20
Fahri Bayram, Halit Diri, Elif Funda Sener, Munis Dundar, Yasin Simsek
PURPOSE: The aim of this study was to evaluate the roles of factors associated with coagulation in the etiology and pathogenesis of Sheehan's syndrome (SS) which is a frequent cause of hypopituitarism in underdeveloped and developing regions of the world. METHODS: Mean prothrombin time (PT), activated partial thromboplastin time (APTT) and expression levels of genes, which included methylenetetrahydrofolate reductase (MTHFR), angiotensin I converting enzyme (ACE), coagulation factor V (FV), FVII, FVIII and FIX in 44 patients with SS were compared with 43 healthy subjects...
November 2016: Gynecological Endocrinology
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