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Elisa Gobbini, Monia Ezzalfani, Véronique Dieras, Thomas Bachelot, Etienne Brain, Marc Debled, William Jacot, Marie Ange Mouret-Reynier, Anthony Goncalves, Florence Dalenc, Anne Patsouris, Jean Marc Ferrero, Christelle Levy, Veronique Lorgis, Laurence Vanlemmens, Claudia Lefeuvre-Plesse, Simone Mathoulin-Pelissier, Thierry Petit, Lionel Uwer, Christelle Jouannaud, Marianne Leheurteur, Magali Lacroix-Triki, Audrey Lardy Cleaud, Mathieu Robain, Coralie Courtinard, Christian Cailliot, David Perol, Suzette Delaloge
AIM: Real-life analysis of overall survival (OS) trends among metastatic breast cancer (MBC) patients may help define medical needs and evaluate the impact of public health investments. The present study aimed to evaluate the independent impact of the year of MBC diagnosis on OS in the Epidemio-Strategy-Medical-Economical (ESME)-MBC cohort. METHODS: ESME-MBC (NCT03275311) is a French, national, multicentre, observational cohort including 16,702 consecutive newly diagnosed MBC patients (01 January 2008-31 December 2014)...
April 13, 2018: European Journal of Cancer
Almut Prkno, Matthias Kaiser, Daniela Goerigk, Martin Pfeffer, Thomas W Vahlenkamp, Donata Hoffmann, Martin Beer, Alexander Starke
Cowpox virus (CPXV) infection is a reportable and potentially zoonotic disease that occurs sporadically in a variety of animals. During the past six decades, CPXV infection has been extensively researched and described in both domestic (cat, dog, horse, cattle) and zoo animals (e. g. elephant, rhinoceros, okapi). Of note, a review of the literature produced only three reports of CPXV in individual or small groups of South American camelids. The goal of this review was to describe the current knowledge as it relates to clinical features of CPXV infection in South American camelids and to compare the clinical manifestations with those described in other animal species...
February 2018: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
Hana Sahli, Aicha Ben Tekaya, Selim Daas, Ines Mahmoud, Rawdha Tekaya
BACKGROUND: Knee osteoarthritis is a common pathology, characterized by a prevalence that increases with age. Absence of anatomo-clinical correlation its management complex, particularly in a geriatric setting where it is not well studied. OBJECTIVE: The aim of the present study is to investigate the epidemio-clinical profile, functional impairment and radiographic features of knee osteoarthritis in the old patients versus younger patients (<65 years). METHODS: Cross-sectional study including patients who were monitored for 6 months at a rheumatology department for knee osteoarthritis...
April 25, 2017: Current Rheumatology Reviews
Mariem Ben Jmaa, Olfa Abida, Emna Bahloul, Amina Toumi, Sana Khlif, Raouia Fakhfakh, Nesrine Elloumi, Khadija Sellami, Abderrahmen Masmoudi, Hamida Turki, Hatem Masmoudi
OBJECTIVE: Forkhead box P3 (FOXP3) is an essential and crucial transcription factor of regulatory T-cells. Genetic polymorphisms in the promoter region of FOXP3 gene may alter the gene expression level and, therefore, contribute to several autoimmune diseases susceptibility. We aimed to investigate the possible role of genetic variants of four SNPs (rs3761547, rs3761548, rs3761549 and rs2294021) and a (GT)n microsatellite located in FOXP3 gene in the susceptibility to Tunisian Pemphigus Foliaceus (PF)...
April 2017: Immunology Letters
Abhishek Binnani, Priyanka Soni Gupta, Ankur Gupta
AIM AND OBJECTIVES: Mycotic keratitis, with its diverse clinical presentation and difficulties in treatment, makes it a challenging task for clinicians and an important object of study. The aim of present study was to determine the frequency of occurrence and epidemiological association with identification of fungal isolates from mycotic keratitis cases. MATERIALS AND METHODS: This was a prospective and observational study conducted in Mycology Laboratory, Department of Microbiology, S...
December 29, 2016: Mycopathologia
Mathilde Ginhoux, Eric Morignat, Anne Bronner, Didier Calavas
Maintaining vigilance with regard to the introduction of exotic diseases is a challenge, particularly because these diseases are numerous, some are not well known, and they are not immediately suspected by people in day-to-day practice, specifically veterinary practitioners. The objective of this article is to present a tool to support the identification of suspect cases of exotic diseases in cattle, based on a Bayesian approach. A list of 22 exotic diseases in mainland France was selected mainly on the basis of their potential consequences if introduced, and the ability to detect them on a clinical basis...
December 1, 2016: Preventive Veterinary Medicine
Maryam Hakkour, Asmae Hmamouch, Mohamed Mahmoud El Alem, Abdelkbir Rhalem, Fatima Amarir, Mohamed Touzani, Abderrahim Sadak, Hajiba Fellah, Faiza Sebti
BACKGROUND: Leishmaniasis is considered among the main endemic diseases in Morocco. However, further knowledge about epidemiological aspects of this disease is needed in several provinces to plan control and preventive strategies to tackle the disease. The present study aims to determine the epidemiological aspect of cutaneous and visceral leishmaniasis in Taza Province from 2007-2014 and to identify the circulating species in this province. RESULTS: The temporal study from 2007 to 2014 showed that the number of cutaneous leishmaniasis cases increased since 2010...
November 29, 2016: Parasites & Vectors
M Moustarhfir, B Bresson, P Koch, A Perozziello, G Barreau, E Schouman-Claeys, M-C Henry-Feugeas, P Ou, B Dallaudière
PURPOSE: The purpose of our prospective study was to assess the presentation of Schmorl's nodes (SN) on magnetic resonance imaging (MRI) and investigate their possible association with demographic and clinical findings. MATERIALS AND METHODS: Three hundred and thirty-three patients were prospectively included. Thirteen (3.9%) patients were excluded because of contraindication to MRI and/or Scheuermann's disease. The final study population included 320 patients. T1-weighted and short TI inversion recovery sequences were performed to assess SN prevalence, the vertebral level and their anatomical distribution in vertebra...
April 2016: Diagnostic and Interventional Imaging
I Bentebbaa, S Elkarimi, M Elhattaoui, L Bendriss, A Elkhatouri
OBJECTIFS: L'objectif de notre étude est de déterminer la fréquence de l'HTA résistante et de décrire ses aspects cliniques et thérapeutiques. MéTHODES: De janvier 2013 à avril 2015, nous avons inclus de manière consécutive les hypertendus suivis dans deux Centres Hospitaliers de la ville de Marrakech, sous traitement antihypertenseur à dose optimale et observants. Les patients dont la pression artérielle était non contrôlée (malgré une triple thérapie anti-hypertensive à dose optimale, comprenant un diurétique associé aux mesures hygiéno-diététiques) ont bénéficié d'une mesure ambulatoire de la tension artérielle...
December 2015: Annales de Cardiologie et D'angéiologie
Iná S Santos, Aluísio J D Barros, Alicia Matijasevich, Roberta Zanini, Maria Aurora Chrestani Cesar, Fabio Alberto Camargo-Figuera, Isabel O Oliveira, Fernando C Barros, Cesar G Victora
This is an update of the 2004 Pelotas Birth Cohort profile, originally published in 2011. In view of the high prevalence of overweight and mental health problems among Brazilian children, together with the availability of state-of-the-art equipment to assess body composition and diagnostic tests for mental health in childhood, the main outcomes measured in the fifth follow-up (mean age 6.8 years) included child body composition, mental health and cognitive ability. A total of 3722 (90.2%) of the original mothers/carers were interviewed and their children examined in a clinic where they underwent whole-body dual X-ray absorptiometry (DXA), air displacement plethysmography and a 3D photonic scan...
October 2014: International Journal of Epidemiology
N Ivoke, O N Ivoke, C D Nwani, F N Ekeh, C N Asogwa, C I Atama, J E Eyo
A twelve-month epidemio-ecological study on the prevalence, infection intensity, water contact and vector aspects of urinary schistosomiasis was conducted in a rural community of south-west Ebonyi State, Nigeria, using standard procedures, and involving 894 individuals (527, 58.9% males; and 367, 41.1% females). An overall community prevalence (15.3%) was established with more males (20.7%) than females (7.6%) being significantly positive for both micro-and macro-haematuria (χ² = 0.806; df = 1, p < 0.05)...
March 2014: Tropical Biomedicine
Hye-Kyung Jung, Youn Hee Kim, Joo Yeon Park, Bo Hyoung Jang, Sun-Young Park, Mi-Hee Nam, Myung-Gyu Choi
BACKGROUND/AIMS: Management of irritable bowel syndrome (IBS) imposes a heavy economic burden. This study was to estimate the epidemio-logic features of IBS and to report the IBS burden for the first time in the Korean population. METHODS: A cross-sectional study was conducted using the National Health Insurance (NHI) system database, which covers the entire pop-ulation of Korea. IBS was defined as diagnostic code -10 in adults with any outpatient clinic visits or hospitalization related to IBS...
April 30, 2014: Journal of Neurogastroenterology and Motility
Helen Gonçalves, Maria Cf Assunção, Fernando C Wehrmeister, Isabel O Oliveira, Fernando C Barros, Cesar G Victora, Pedro C Hallal, Ana Mb Menezes
In this paper we update the profile of the 1993 Pelotas (Brazil) Birth Cohort Study, with emphasis on a shift of priority from maternal and child health research topics to four main categories of outcome variables, collected throughout adolescence: (i) mental health; (ii) body composition; (iii) risk factors for non-communicable diseases (NCDs); (iv) human capital. We were able to trace 81.3% (n = 4106) of the original cohort at 18 years of age. For the first time, the 18-years visit took place entirely on the university premises, in a clinic equipped with state-of-the-art equipment for the assessment of body composition...
August 2014: International Journal of Epidemiology
Pavla Křížová, Zuzana Vacková, Martin Musílek, Jana Kozáková
AIMS: Analysis of invasive meningococcal disease (IMD) surveillance data including molecular epidemio-logy data. Vaccination strategy recommendations based on the current epidemiological situation of IMD in the Czech Republic and availability of meningococcal vaccines. MATERIAL AND METHODS: IMD surveillance data are compiled by the National Reference Laboratory for Meningococcal Disease (NRL) from routinely reported data and NRL data after clearing out duplicate data...
December 2013: Epidemiologie, Mikrobiologie, Imunologie
Duncan Mwangangi Matheka, Jolynne Mokaya, Marybeth Maritim
The World Health Organization (WHO) estimates that acute lower respiratory infections account for 4 million deaths per year. The rates are even higher in developing countries. Influenza, a virus causing respiratory infections, has widely been studied in developed countries. However, there is paucity of data on its epidemiology, seasonality and burden in most developing countries. In the contrary, Kenya (a developing country) has an elaborate national epidemio-surveillance network for influenza, where a lot of data is generated on the epidemiology and seasonality of influenza in Kenya and the East African region...
2013: Pan African Medical Journal
Sana Chouk Friaa, Talel Badri, Houda Hammami, Rym Benmously, Hayet Marrak, Aschraf Debbiche, Incaf Mokhtar, Samy Fenniche
BACKGROUND: Dermatofibrosarcoma protuberans is the most common mesenchymatous skin tumor. It is often diagnosed late because of its slow development and the lack of symptoms. AIM: To elucidate the epidemio-clinical characteristics of dermatofibrosarcoma in our study. methods: We report a retrospective study of 18 cases of DFS between 1989 and 2009. RESULTS: Mean age at diagnosis was 45.2 years. The average delay before consultation was 45...
May 2013: La Tunisie Médicale
L J Legrand, P-H Y Pitel, C J Marcillaud-Pitel, A A Cullinane, A M Couroucé, G D Fortier, F L Freymuth, S L Pronost
REASONS FOR PERFORMING THE STUDY: The Réseau d'Epidémio-Surveillance en Pathologie Equine (RESPE, the French epidemiological network for equine diseases) is a network for epidemio-surveillance of major equine diseases based around sentry veterinarians in France. OBJECTIVE: The aim of this study was to evaluate the contribution of RESPE to efficient surveillance of equine influenza virus (EIV) in France. STUDY DESIGN: Retrospective cross-sectional study...
November 2013: Equine Veterinary Journal
Jun Li, He-Yi Zheng
BACKGROUND: Erythroderma is a rare skin disorder and studies on its causes and prognosis are rare in the literature. OBJECTIVES: We reviewed the clinical, laboratory and biopsy materials of 260 patients diagnosed with erythroderma who were treated in our department over an 11-year period. Patients were followed up to better understand the evolution of erythroderma. METHODS: This study was performed at our hospital between January 2001 and 2012 and included 260 patients with erythroderma...
2012: Dermatology: International Journal for Clinical and Investigative Dermatology
B M Samaké, M Traoré, L Goita, M Niani, Y Traoré, I Teketé, A Diallo, A Dolo
AIMS: To determine the epidemio-clinical profile of severe pre-eclampsia. PATIENTS AND METHOD: It was about a transversal study done from November 2005 to juin 2006 at the teaching hospital Gabriel Touré. Were included pregnant women with severe pre-eclampsia. Statistical analysis compared the proportions and means, the proportions were compared using the chi (2 with) P < 0,05 considered significant. RESULTS: during the period of study, 130 cares of severe pré-eclamsia were brougthbto gether among 1667 pregnant women, which was 7,8 %...
2011: Le Mali Médical
Delphine Lutringer-Magnin, Nicolas Girard, Jacques Cadranel, Caroline Leroux, Elisabeth Quoix, Vincent Cottin, Corinne Del Signore, Marie-Paule Lebitasy, Geneviève Cordier, Philippe Vanhems, Jean-François Mornex
Pneumonic-type lung adenocarcinoma (P-ADC) represents a distinct subset of lung cancer with specific clinical, radiological, and pathological features. Given the weak association with tobacco-smoking and the striking similarities with jaagsiekte sheep retrovirus (JSRV)-induced ovine pulmonary adenocarcinoma, it has been suggested that a zoonotic viral agent infecting pulmonary cells may predispose to P-ADC in humans. Our objective was to explore whether exposure to domestic small ruminants may represent a risk factor for P-ADC...
2012: PloS One
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