keyword
https://read.qxmd.com/read/38394227/defining-practice-capacity-for-cancer-care-delivery-to-adolescents-and-young-adults-in-the-community-setting-2022-landscape-assessment-results
#1
JOURNAL ARTICLE
Melissa P Beauchemin, Lingyun Ji, AnnaLynn M Williams, Chandylen L Nightingale, Emily V Dressler, John M Salsman, Sheila J Santacroce, David R Freyer, Michael E Roth, Susan K Parsons
Background: Adolescents and young adults (AYAs) commonly receive cancer care in the community setting, but the availability of treatment options, resources, and support services for this population is not well known. The National Cancer Institute Community Oncology Research Program (NCORP) funds a network of practices whose mission is to increase access to cancer care and clinical trials in the community setting. We describe our interdisciplinary methodological approach to identify and characterize NCORP practices where AYAs receive cancer care...
February 23, 2024: Journal of Adolescent and Young Adult Oncology
https://read.qxmd.com/read/38374401/increasing-diversity-in-clinical-trials-demographic-trends-at-the-national-cancer-institute-2005-2020
#2
JOURNAL ARTICLE
Nirmal Choradia, Fatima Karzai, Ryan Nipp, Abdul Rafeh Naqash, James L Gulley, Charalampos S Floudas
BACKGROUND: We described participant demographics for National Cancer Institute (NCI) clinical trials at the Clinical Center (CC) of the National Institutes of Health (NIH) (NCI-CC participants) to identify enrollment disparities. METHODS: We analyzed NCI-CC data from 2005-2020, calculated enrollment fractions (EF), compared with the U.S. cancer population represented by the Surveillance, Epidemiology, and End Results (SEER) cancer incidence data (2018) and the Cancer in North American (CiNA) database (2018), and with clinical trial disparities data from NCI's Community Oncology Research Program (NCORP) and National Clinical Trials Network (NCTN) (2005-2019), and from ClinicalTrials...
February 19, 2024: Journal of the National Cancer Institute
https://read.qxmd.com/read/38291716/clinical-practice-guideline-inconsistent-management-of-fever-and-neutropenia-in-pediatric-oncology-a-children-s-oncology-group-study
#3
JOURNAL ARTICLE
L Lee Dupuis, Brian T Fisher, A J Sugalski, Allison Caren Grimes, Michelle Nuño, S Ramakrishnan, M P Beauchemin, Paula D Robinson, Nancy Santesso, Alexandra Walsh, A R Wrightson, Lolie Yu, Susan K Parsons, Lillian Sung
BACKGROUND: The primary objective was to measure the proportion of episodes where care delivery was inconsistent with selected recommendations of a clinical practice guideline (CPG) on fever and neutropenia (FN) management. The influence of site size on CPG-inconsistent care delivery, and association between patient outcomes and CPG-inconsistent care were described. METHODS: This retrospective, multicenter study included patients less than 21 years old with cancer who were at high risk of poor FN outcomes and were previously enrolled to a Children's Oncology Group (COG) study at participating National Cancer Institute Community Oncology Research Program (NCORP) institutions from January 2014 through December 2015...
January 30, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38280052/randomized-placebo-controlled-double-blind-clinical-trial-of-nanoemulsion-curcumin-in-women-with-aromatase-inhibitor-induced-arthropathy-an-alliance-ncorp-pilot-trial
#4
JOURNAL ARTICLE
Maryam Lustberg, Patty Fan-Havard, F Lennie Wong, Kasey Hill, Mitch A Phelps, Kevin W Herrera, Ni-Chun Tsai, Timothy Synold, Ye Feng, Chidimma Kalu, Mina S Sedrak, Lisa D Yee
PURPOSE: Aromatase inhibitor (AI) therapy reduces risk of recurrence and death for postmenopausal women with breast cancer (BC); however, AI-induced arthralgia (AIIA) can lead to discontinuation of treatment. Curcumin, a bioactive polyphenolic substance, may help ameliorate inflammation-related conditions including osteoarthritis and pain. METHODS: We conducted a multisite randomized placebo-controlled, double-blind pilot trial (Alliance A22_Pilot9) to evaluate the effects of nanoemulsion curcumin (NEC, 200 mg/day) in postmenopausal women experiencing AIIA for ≥ 3 months...
January 27, 2024: Breast Cancer Research and Treatment
https://read.qxmd.com/read/38268476/availability-of-cancer-survivorship-support-services-across-the-nci-community-oncology-research-program-ncorp-network
#5
JOURNAL ARTICLE
Jamie M Faro, Emily V Dressler, Carol Kittel, Dori M Beeler, Shirley M Bluethmann, Stephanie J Sohl, Andrew M McDonald, Kathryn E Weaver
BACKGROUND: National cancer organizations recommend provision of nutrition, physical activity, and mental health supportive services to cancer survivors. However, the availability of these services across diverse community oncology settings remains unclear. METHODS: The NCI Community Oncology Research Program (NCORP) is a national network of community oncology practices engaged in cancer research. The 2022 NCORP Landscape Assessment (5UG1CA189824) assessed individual practices' establishment of survivorship clinics and nutrition, physical activity, and mental health services, resources, and/or referrals...
January 24, 2024: JNCI Cancer Spectrum
https://read.qxmd.com/read/38252911/characteristics-of-health-care-settings-where-adolescents-and-young-adults-receive-care-for-all
#6
JOURNAL ARTICLE
Julie A Wolfson, Allison C Grimes, Michelle Nuno, Charlotte L Kerber, Subhash Ramakrishnan, Melissa Beauchemin, David Dickens, Jennifer M Levine, Michael E Roth, Michele Scialla, Wendy Woods, Sarah Vargas, Koh B Boayue, George J Chang, Wendy Stock, Dawn Hershman, Emily Curran, Anjali Advani, Kristen O'Dwyer, Selina Luger, Jane Jijun Liu, David R Freyer, Lillian Sung, Susan K Parsons
PURPOSE: Individuals diagnosed with cancer between 15 and 39 years (adolescent and young adult [AYA]) face unique vulnerability. Detail is lacking about care delivery for these patients, especially those with ALL. We address these knowledge gaps by describing AYA ALL care delivery details at National Cancer Institute Community Oncology Research Program (NCORP) (sub)affiliates by model of care. METHODS: Participating institutions treated at least one AYA with ALL from 2012 to 2016...
January 22, 2024: JCO oncology practice
https://read.qxmd.com/read/38175992/defining-the-role-of-the-advanced-practice-provider-within-the-national-cancer-institute-community-oncology-research-program
#7
JOURNAL ARTICLE
Christa M Braun-Inglis, Emily V Dressler, Jamie S Myers, Al B Benson, Marie Flannery, Marjorie Good, Andrea Denicoff, Jeffrey L Berenberg, Alisha T DeTroye, Bridget O'Brien, Lisa Kottschade, Dee Ann Omatsu, Carol A Kittel, Chandylen L Nightingale, Melyssa Foust, Glenn J Lesser
PURPOSE: Oncology advanced practice providers (APPs), including nurse practitioners, clinical nurse specialists, physician assistants, and clinical pharmacists, contribute significantly to quality cancer care. Understanding the research-related roles of APPs in the National Cancer Institute's (NCI) Community Oncology Research Program (NCORP) could lead to enhanced protocol development, trial conduct, and accrual. METHODS: The 2022 NCORP Landscape Assessment Survey asked two questions about the utilization and roles of APPs in the NCORP...
February 2024: JCO oncology practice
https://read.qxmd.com/read/37993030/wireless-transcutaneous-electrical-nerve-stimulation-tens-for-chronic-chemotherapy-induced-peripheral-neuropathy-cipn-a-proof-of-concept-randomized-clinical-trial
#8
JOURNAL ARTICLE
Jennifer S Gewandter, Eva Culakova, Jenae N Davis, Umang Gada, Joseph J Guido, James D Bearden, Brain Burnette, Dhaval Shah, Gary R Morrow, Karen Mustian, Kathleen A Sluka, Nimish Mohile
Chemotherapy-induced peripheral neuropathy (CIPN) affects approximately 30 to 60% of people who receive neurotoxic chemotherapy. CIPN is associated with impaired quality of life and function and has few effective treatments. This 6-site, subject and assessor-blinded randomized clinical trial (RCT) was designed to assess 1) preliminary efficacy (ie, alpha pre-specified at .2) of a wearable, app-controlled, transcutaneous electrical nerve stimulation (TENS) device for chronic CIPN and 2) feasibility of conducting a confirmatory trial within the National Cancer Institute Community Oncology Research Program (NCORP) (NCT04367480)...
November 21, 2023: Journal of Pain
https://read.qxmd.com/read/37785505/the-theoretical-role-for-radiotherapy-in-patients-with-diffuse-large-b-cell-lymphoma-a-secondary-analysis-of-a-prospective-randomized-controlled-trial
#9
JOURNAL ARTICLE
C M Lanier, N Razavian, R T Hughes
PURPOSE/OBJECTIVE(S): The role of radiotherapy (RT) for diffuse large B-cell lymphoma (DLBCL) is unclear. In patients treated with upfront chemotherapy for DLBCL, indications for RT are often considered to be bulky (7.5 cm +) or extranodal disease. This is thought to improve outcomes through improvement in local control. Many trials call into question the actual benefit of RT. Alliance/CALGB 50303 was a randomized phase III trial comparing two chemotherapy regimens for the treatment for DLBCL in which no patients were to receive RT...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37738445/processes-for-identifying-caregivers-and-screening-for-caregiver-and-patient-distress-in-community-oncology-results-from-wf-1803cd
#10
JOURNAL ARTICLE
Chandylen L Nightingale, Anna C Snavely, Laurie E McLouth, Emily V Dressler, Erin E Kent, Christian S Adonizio, Suzanne C Danhauer, Rachel Cannady, Judith O Hopkins, Heather Kehn, Kathryn E Weaver, Katherine R Sterba
BACKGROUND: Despite their vital roles, informal caregivers of adult cancer patients are commonly overlooked in cancer care. This study describes processes for identifying cancer caregivers and processes for distress screening and management among caregivers and patients in the understudied community oncology setting. METHODS: Supportive care leaders (SCLs) from NCI Community Oncology Research Program (NCORP) practices completed online survey questions regarding caregiver identification, caregiver and patient distress screening, and distress management strategies...
September 21, 2023: Journal of the National Cancer Institute
https://read.qxmd.com/read/37732470/barriers-facilitators-and-recommendations-for-sexual-orientation-and-gender-identity-data-collection-in-community-oncology-practices
#11
JOURNAL ARTICLE
Megan A Mullins, Lisa Reber, Ariel Washington, Marina Stasenko, Aaron Rankin, Christopher R Friese, Mary E Cooley, Matthew F Hudson, Lauren P Wallner
BACKGROUND: Sexual orientation and gender identity (SOGI) data collection in community oncology practices is critical to identify and address cancer inequities, but less than 20% of NCI Community Oncology Research Program (NCORP)-affiliated practices regularly collect SOGI data despite widespread recommendations. We evaluated multilevel barriers and facilitators for SOGI data collection at NCORP practices. METHODS: We conducted 14 semi-structured interviews at seven purposefully sampled NCORP oncology practices...
September 21, 2023: Cancer Medicine
https://read.qxmd.com/read/37561111/assessment-of-financial-screening-and-navigation-capabilities-at-nci-community-oncology-clinics
#12
JOURNAL ARTICLE
Ari Bell-Brown, Kate Watabayashi, Debbie Delaney, Ruth C Carlos, Shelby L Langer, Joseph M Unger, Riha R Vaidya, Amy K Darke, Dawn L Hershman, Scott D Ramsey, Veena Shankaran
BACKGROUND: Cancer-related financial hardship is a side effect of cancer diagnosis and treatment, and impacts both patients and caregivers. While many oncology clinics have increased financial navigation services, few have resources to proactively provide financial counseling and assistance to families impacted by cancer before financial hardship occurs. As part of an ongoing randomized study testing a proactive financial navigation intervention (S1912CD) among NCI Community Oncology Research Program (NCORP) sites, we conducted a baseline survey to learn more about existing financial resources available to patients and caregivers...
August 10, 2023: JNCI Cancer Spectrum
https://read.qxmd.com/read/37540817/information-technology-and-telemedicine-services-in-community-oncology-practices
#13
JOURNAL ARTICLE
Kah Poh Loh, Ying Wang, Sule Yilmaz, Chandylen L Nightingale, Susan K Parsons, Christa Braun-Inglis, Umang Gada, Alexander Montes, Allison Magnuson, Eva Culakova, Sarah Strause, Charles Kamen, Emily Dressler, Karen Mustian, Gary Morrow, Supriya Mohile
PURPOSE: We described information technology support and use of telemedicine for cancer care and research purposes at community oncology practices within the National Cancer Institute Community Oncology Research Program (NCORP). METHODS: We used data from the NCORP 2017 and 2022 Landscape Assessments. Separate logistic regression models were used to assess factors associated with the use of telemedicine for delivery of cancer care in 2017 and for research purposes in 2022 (cancer care delivery not assessed in 2022)...
August 2023: JCO Clinical Cancer Informatics
https://read.qxmd.com/read/37469004/children-s-oncology-group-2023-blueprint-for-research-cancer-care-delivery-research
#14
JOURNAL ARTICLE
Susan K Parsons, Melissa P Beauchemin, Lee Dupuis, Aaron Sugalski, Julie Anna Wolfson, Sheila J Santacroce, Jordan G Marchak, Lillian Sung, Michael E Roth
The National Cancer Institute (NCI) has a 40-year history of initiatives to encourage the participation of community oncology sites into clinical trials research and clinical care. In 2014, the NCI re-organized to form the NCI Community Oncology Research Program (NCORP) network across seven research bases, including the Children's Oncology Group (COG), and numerous community sites. The COG portfolio for Cancer Care Delivery Research (CCDR), mirroring the larger NCORP network, has included two studies addressing guideline congruence, as an important marker of quality cancer care, and another focusing on financial toxicity, addressing the pervasive problems of healthcare cost...
September 2023: Pediatric Blood & Cancer
https://read.qxmd.com/read/37343707/interpretable-machine-learning-for-choosing-radiation-dose-volume-constraints-on-cardio-pulmonary-substructures-associated-with-overall-survival-in-nrg-oncology-rtog-0617
#15
JOURNAL ARTICLE
Sang Ho Lee, Huaizhi Geng, Jacinta Arnold, Richard Caruana, Yong Fan, Mark A Rosen, Aditya P Apte, Joseph O Deasy, Jeffrey D Bradley, Ying Xiao
PURPOSE: Our objective was to use interpretable machine learning for choosing dose-volume constraints on cardiopulmonary substructures (CPSs) associated with overall survival (OS) in radiation therapy for locally advanced non-small cell lung cancer. METHODS AND MATERIALS: A total of 428 patients with non-small cell lung cancer were randomly divided into training/validation/test subsets (n = 230/149/49) in Radiation Therapy Oncology Group 0617. Manual or automated contouring was performed to segment CPSs, including heart, atria, ventricles, aorta, left/right ventricle/atrium (LV+RV+LA+RA), inferior/superior vena cava, pulmonary artery, and pericardium...
June 19, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37248119/oncologists-perceived-confidence-and-attitudes-toward-managing-pre-existing-chronic-comorbidities-during-patients-active-cancer-treatment
#16
JOURNAL ARTICLE
Dudith Pierre-Victor, Iman K Martin, Brenda Adjei, Mary Shaw-Ridley, Bruce Rapkin, Marjorie Good, Diane St Germain, Bernard Parker, Paul F Pinsky, Worta McCaskill-Stevens
PURPOSE: To examine practicing oncologists' perceived confidence and attitudes toward management of pre-existing chronic conditions(PECC) during active cancer treatment(ACT). METHODS: In December 2018, oncologists in the National Cancer Institute's Community Oncology Research Program (NCORP) were invited to complete a was pilot-tested, IRB-approved online survey about their perceived confidence in managing PECC. Pearson chi-square test was used to identify oncologists' differences in perceived confidence to manage PECC and attitudes toward co-management of patients' PECC with non-oncologic care providers...
May 27, 2023: Journal of the National Medical Association
https://read.qxmd.com/read/37224793/endometrial-cancer-survivors-perceptions-of-their-cardiovascular-disease-risk-results-from-wf-1804cd-ah-ha
#17
JOURNAL ARTICLE
Joseph A DeMari, Emily V Dressler, Randi E Foraker, Brian J Wells, Sydney Smith, Heidi Klepin, William G Hundley, Glenn J Lesser, David I Shalowitz, Chandylen L Nightingale, Marcia Hernandez, Kathryn E Weaver
OBJECTIVE: Despite considerable burden of cardiovascular disease (CVD), data on endometrial cancer survivors' CVD perceptions are lacking. We assessed survivors' perspectives on addressing CVD risk during oncology care. METHODS: This cross-sectional analysis utilized data from an ongoing trial of an EHR heart health tool (R01CA226078 & UG1CA189824) conducted through the NCI Community Oncology Research Program (NCORP, WF-1804CD). Endometrial cancer survivors post-potentially curative treatment were recruited from community practices and completed a pre-visit baseline survey, including American Heart Association Simple 7 CVD factors...
May 22, 2023: Gynecologic Oncology
https://read.qxmd.com/read/37029555/reducing-anxiety-and-dyspnea-via-device-guided-breathing-relax-a-multi-site-feasibility-study-in-post-treatment-lung-cancer-survivors-at-community-cancer-clinics-wf-01213
#18
JOURNAL ARTICLE
Suzanne C Danhauer, Emily V Dressler, W Mark Brown, Chandylen L Nightingale, Gretchen A Brenes, William J Petty, Amarinthia Curtis, Srujitha Murkutla, Jocelin Huang, Cheyenne R Wagi, Glenn J Lesser, Kathryn E Weaver
INTRODUCTION: Anxiety and dyspnea are 2 common symptoms for lung cancer survivors. Although research suggests decreasing respiration rate can reduce anxiety in several populations, potential benefits of device-guided breathing have not been studied in lung cancer survivors. This feasibility study (WF-01213) provides estimates of accrual, adherence, retention, and preliminary efficacy of 2 doses of a device-guided breathing intervention versus a usual breathing control group for improving self-reported anxiety and dyspnea in post-treatment lung cancer survivors...
2023: Integrative Cancer Therapies
https://read.qxmd.com/read/36931460/the-optimizing-lung-screening-trial-wf-20817cd-multicenter-randomized-effectiveness-implementation-trial-to-increase-tobacco-use-cessation-for-individuals-undergoing-lung-screening
#19
RANDOMIZED CONTROLLED TRIAL
Kristie L Foley, Emily V Dressler, Kathryn E Weaver, Erin L Sutfin, David P Miller, Christina Bellinger, Carol Kittel, Rebecca J Stone, W Jeffrey Petty, Stephanie R Land, John G Spangler, Glenn J Lesser, Caroline Chiles
BACKGROUND: One-half of all people who undergo lung cancer screening (LCS) currently use tobacco. However, few published studies have explored how to implement effective tobacco use treatment optimally during the LCS encounter. RESEARCH QUESTION: Was the Optimizing Lung Screening intervention (OaSiS) effective at reducing tobacco use among patients undergoing LCS in community-based radiology facilities? STUDY DESIGN AND METHODS: The OaSiS study (National Cancer Institute [NCI] Protocol No...
August 2023: Chest
https://read.qxmd.com/read/36609349/improving-patient-centered-communication-in-breast-cancer-a-study-protocol-for-a-multilevel-intervention-of-a-shared-treatment-deliberation-system-shares-within-the-nci-community-oncology-research-program-ncorp-alliance-a231901cd
#20
JOURNAL ARTICLE
Sarah T Hawley, Kelley Kidwell, David Zahrieh, Anne McCarthy, Rachel Wills, Aaron Rankin, Timothy Hofer, Selina Chow, Reshma Jagsi, Heather Neuman
BACKGROUND: Advances in precision medicine have given oncologists new evaluative tools to better individualize treatments for patients with curable breast cancer. These innovations have revealed a need to improve patient understanding of novel, often complex information related to breast cancer treatment decisions. Ensuring patients have the emotional support to face consequential treatment decisions, as well as the opportunity to engage and discuss with their clinicians, is key to improving patient-centered communication and patient understanding...
January 6, 2023: Trials
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