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Pancreas MR

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https://www.readbyqxmd.com/read/27898201/diffusion-weighted-imaging-of-the-abdomen-impact-of-b-values-on-texture-analysis-features
#1
Anton S Becker, Matthias W Wagner, Moritz C Wurnig, Andreas Boss
The purpose of this work was to systematically assess the impact of the b-value on texture analysis in MR diffusion-weighted imaging (DWI) of the abdomen. In eight healthy male volunteers, echo-planar DWI sequences at 16 b-values ranging between 0 and 1000 s/mm(2) were acquired at 3 T. Three different apparent diffusion coefficient (ADC) maps were computed (0, 750/100, 390, 750 s/mm(2) /all b-values). Texture analysis of rectangular regions of interest in the liver, kidney, spleen, pancreas, paraspinal muscle and subcutaneous fat was performed on DW images and the ADC maps, applying 19 features computed from the histogram, grey-level co-occurrence matrix (GLCM) and grey-level run-length matrix (GLRLM)...
November 29, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27868105/feasibility-of-automated-3-dimensional-magnetic-resonance-imaging-pancreas-segmentation
#2
Shuiping Gou, Percy Lee, Peng Hu, Jean-Claude Rwigema, Ke Sheng
PURPOSE: With the advent of MR guided radiotherapy, internal organ motion can be imaged simultaneously during treatment. In this study, we evaluate the feasibility of pancreas MRI segmentation using state-of-the-art segmentation methods. METHODS AND MATERIAL: T2 weighted HASTE and T1 weighted VIBE images were acquired on 3 patients and 2 healthy volunteers for a total of 12 imaging volumes. A novel dictionary learning (DL) method was used to segment the pancreas and compared to t mean-shift merging (MSM), distance regularized level set (DRLS), graph cuts (GC) and the segmentation results were compared to manual contours using Dice's index (DI), Hausdorff distance and shift of the-center-of-the-organ (SHIFT)...
July 2016: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/27832518/expanding-the-scope-of-an-automated-radiology-recommendation-tracking-engine-initial-experiences-and-lessons-learned
#3
Mindy Y Licurse, Darco Lalevic, Hanna M Zafar, Mitchell D Schnall, Tessa S Cook
An automated radiology recommendation-tracking engine for incidental focal masses in the liver, pancreas, kidneys, and adrenal glands was launched within our institution in July 2013. For 2 years, the majority of CT, MR, and US examination reports generated within our health system were mined by the engine. However, the need to expand the system beyond the initial four organs was soon identified. In July 2015, the second phase of the system was implemented and expanded to include additional anatomic structures in the abdomen and pelvis, as well as to provide non-radiology and non-imaging options for follow-up...
November 10, 2016: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/27760203/correction-preliminary-study-of-mr-diffusion-tensor-imaging-of-pancreas-for-the-diagnosis-of-acute-pancreatitis
#4
Xinghui Li, Ling Zhuang, Xiaoming Zhang, Jian Wang, Tianwu Chen, Liangjun Li, Emmanuel Ajedichiga Aduah, Jiani Hu
[This corrects the article DOI: 10.1371/journal.pone.0160115.].
2016: PloS One
https://www.readbyqxmd.com/read/27699875/tomoelastography-of-the-abdomen-tissue-mechanical-properties-of-the-liver-spleen-kidney-and-pancreas-from-single-mr-elastography-scans-at-different-hydration-states
#5
Florian Dittmann, Heiko Tzschätzsch, Sebastian Hirsch, Eric Barnhill, Jürgen Braun, Ingolf Sack, Jing Guo
PURPOSE: To develop a compact magnetic resonance elastography (MRE) protocol for abdomen and to investigate the effect of water uptake on tissue stiffness in the liver, spleen, kidney, and pancreas. METHODS: Nine asymptomatic volunteers were investigated by MRE before and after 1 liter water uptake. Shear-wave excitation at four frequencies was transferred to the abdomen from anterior and posterior directions using pressurized air drivers. Tomographic representations of shear-wave speed were produced by analysis of multifrequency wave numbers in axial and coronal images acquired within four breath-holds or under free breathing, respectively...
October 3, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27660281/detection-of-exocrine-dysfunction-by-mri-in-patients-with-early-chronic-pancreatitis
#6
Temel Tirkes, Evan L Fogel, Stuart Sherman, Chen Lin, Jordan Swensson, Fatih Akisik, Kumaresan Sandrasegaran
PURPOSE: To determine if T1-weighted MR signal of the pancreas can be used to detect early CP. METHODS: A retrospective analysis was performed on 51 suspected CP patients, who had both secretin-enhanced magnetic resonance cholangiopancreatography (S-MRCP) and an intraductal secretin stimulation test (IDST). There were 29 patients in normal and 22 patients in the low bicarbonate group. Bicarbonate level, total pancreatic juice volume, and excretory flow rate were recorded during IDST...
September 23, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27624753/in-vivo-and-ex-vivo-19-fluorine-magnetic-resonance-imaging-and-spectroscopy-of-beta-cells-and-pancreatic-islets-using-glut-2-specific-contrast-agents
#7
Sayuan Liang, Karim Louchami, Hauke Kolster, Anna Jacobsen, Ying Zhang, Julian Thimm, Abdullah Sener, Joachim Thiem, Willy Malaisse, Tom Dresselaers, Uwe Himmelreich
The assessment of the β-cell mass in experimental models of diabetes and ultimately in patients is a hallmark to understand the relationship between reduced β-cell mass/function and the onset of diabetes. It has been shown before that the GLUT-2 transporter is highly expressed in both β-cells and hepatocytes and that D-mannoheptulose (DMH) has high uptake specificity for the GLUT-2 transporter. As 19-fluorine MRI has emerged as a new alternative method for MRI cell tracking because it provides potential non-invasive localization and quantification of labeled cells, the purpose of this project is to validate β-cell and pancreatic islet imaging by using fluorinated, GLUT-2 targeting mannoheptulose derivatives ((19) FMH) both in vivo and ex vivo...
September 14, 2016: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/27616039/pancreas-divisum-a-risk-factor-for-pancreaticobiliary-tumors%C3%A2-%C3%A2-an-analysis-of-1628-mr-cholangiography-examinations
#8
Z H Adibelli, M Adatepe, L Isayeva, O S Esen, M Yildirim
PURPOSE: This retrospective study was conducted to evaluate the relationships between pancreas divisum, biliary duct anatomical variations and pancreaticobiliary tumors using magnetic resonance cholangiopancreatography (MRCP). MATERIALS AND METHOD: The MRCP examinations of 1628 patients were retrospectively reviewed for the presence of pancreas divisum, biliary duct anatomical variations and pancreaticobiliary tumors. Of these, 90 patients (31 men, 59 women) with a mean age of 62...
September 5, 2016: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/27591177/outcome-of-long-interval-radiological-surveillance-of-side-branch-pancreatic-duct-involved-intraductal-papillary-mucinous-neoplasm-in-selected-patients
#9
Yazan S Khaled, Muhammed Mohsin, Kavi Fatania, Ada Yee, Robert Adair, Maria Sheridan, Christian Macutkiewicz, Amer Aldouri, Andrew M Smith
INTRODUCTION: Side branch IPMN (SB-IPMN) of the pancreas has a malignancy rate between 10 and 20%. We hypothesized that surveillance at longer intervals on selected patients with SB-IPMN might be indicated. METHODS: This is a retrospective study of prospectively collected data of 276 patients presenting from 2000 to 2010. After 2007, we opted to screen our patients with longer intervals, initially at 12 months then 24 months using MR if no "worrisome features" were present...
August 30, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27584016/preliminary-study-of-mr-diffusion-tensor-imaging-of-pancreas-for-the-diagnosis-of-acute-pancreatitis
#10
Xinghui Li, Ling Zhuang, Xiaoming Zhang, Jian Wang, Tianwu Chen, Liangjun Li, Emmanuel Ajedichiga Aduah, Jiani Hu
OBJECTIVES: To evaluate the feasibility of differentiating between acute pancreatitis (AP) and healthy pancreas using diffusion tensor imaging (DTI) and correlate apparent diffusion coefficient (ADC) /fractional anisotropy (FA) values with the severity of AP. MATERIAL AND METHODS: 66 patients diagnosed with AP and 20 normal controls (NC) underwent DTI sequences and routine pancreatic MR sequences on a 3.0T MRI scanner. Average ADC and FA values of the pancreatic were measured...
2016: PloS One
https://www.readbyqxmd.com/read/27573371/extensive-heterotopic-gastric-mucosa-of-the-small-intestine-imaging-with-99m-tc-sodium-pertechnetate-spect-ct-enterography
#11
Andrew H Schapiro, Tom K Lin, Jason S Frischer, Ayaka Silverman, Andrew T Trout
Extensive heterotopic gastric mucosa of the small intestine is a rare, but potentially life-threatening condition characterized by multifocal or long-segment heterotopic gastric mucosa within the bowel lumen that is often associated with other anomalies including malrotation and annular pancreas. Although the imaging findings are characteristic, this entity may be unrecognized due to its unusual imaging appearance and rarity. CT or MR enterography and (99m)Tc-sodium pertechnetate scintigraphy can provide complementary information that enables specific diagnosis and accurate assessment of disease extent...
December 2016: Pediatric Radiology
https://www.readbyqxmd.com/read/27487897/technical-note-dose-effects-of-1-5-t-transverse-magnetic-field-on-tissue-interfaces-in-mri-guided-radiotherapy
#12
Xinfeng Chen, Phil Prior, Guang-Pei Chen, Christopher J Schultz, X Allen Li
PURPOSE: The integration of MRI with a linear accelerator (MR-linac) offers great potential for high-precision delivery of radiation therapy (RT). However, the electron deflection resulting from the presence of a transverse magnetic field (TMF) can affect the dose distribution, particularly the electron return effect (ERE) at tissue interfaces. The purpose of the study is to investigate the dose effects of ERE at air-tissue and lung-tissue interfaces during intensity-modulated radiation therapy (IMRT) planning...
August 2016: Medical Physics
https://www.readbyqxmd.com/read/27487874/an-online-replanning-method-using-warm-start-optimization-and-aperture-morphing-for-flattening-filter-free-beams
#13
Ergun E Ahunbay, O Ates, X A Li
PURPOSE: In a situation where a couch shift for patient positioning is not preferred or prohibited (e.g., MR-linac), segment aperture morphing (SAM) can address target dislocation and deformation. For IMRT/VMAT with flattening-filter-free (FFF) beams, however, SAM method would lead to an adverse translational dose effect due to the beam unflattening. Here the authors propose a new two-step process to address both the translational effect of FFF beams and the target deformation. METHODS: The replanning method consists of an offline and an online step...
August 2016: Medical Physics
https://www.readbyqxmd.com/read/27390542/comparison-of-multidetector-ct-and-gadobutrol-enhanced-mr-imaging-for-evaluation-of-small-solid-pancreatic-lesions
#14
Tae Won Choi, Jeong Min Lee, Jung Hoon Kim, Mi Hye Yu, Joon Koo Han, Byung Ihn Choi
OBJECTIVE: To compare multidetector computed tomography (MDCT) and MRI for lesion conspicuity, as well as the detection and characterization of small solid pancreatic lesions (SPLs). MATERIALS AND METHODS: 193 patients with small SPLs (< 3 cm) and 52 patients with normal pancreas who underwent both multiphasic MDCT and gadobutrol-enhanced MRI were included in our study. Two radiologists blinded to the pathologic diagnoses independently reviewed those images, and determined the detection of "SPL per se" and "SPL in consideration of secondary features", the lesion conspicuity, the probability of pancreatic ductal adenocarcinoma (PDAC), and the most likely specific diagnosis...
July 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27370179/a-case-based-reflection-on-communicating-end-of-life-information-in-non-english-speaking-patients
#15
Carl Hume, Phillipa Malpas
Mr X was a 56year old Chinese man (non-English speaking), who presented to the emergency department with a range of non-specific symptoms. On full workup, he was diagnosed with an advanced cancer of the pancreas. It was an aggressive, highly treatment resistant cancer, with an alarmingly poor prognosis. Before the diagnosis had been made, the family had informed our team that we were not to discuss medical issues with Mr X directly, and that upon arriving on a diagnosis we were to come to them first and they would subsequently inform him...
June 17, 2016: Patient Education and Counseling
https://www.readbyqxmd.com/read/27370138/endoluminal-ultrasound-applicators-for-mr-guided-thermal-ablation-of-pancreatic-tumors-preliminary-design-and-evaluation-in-a-porcine-pancreas-model
#16
Matthew S Adams, Vasant A Salgaonkar, Juan Plata-Camargo, Peter D Jones, Aurea Pascal-Tenorio, Hsin-Yu Chen, Donna M Bouley, Graham Sommer, Kim Butts Pauly, Chris J Diederich
PURPOSE: Endoluminal ultrasound may serve as a minimally invasive option for delivering thermal ablation to pancreatic tumors adjacent to the stomach or duodenum. The objective of this study was to explore the basic feasibility of this treatment strategy through the design, characterization, and evaluation of proof-of-concept endoluminal ultrasound applicators capable of placement in the gastrointestinal (GI) lumen for volumetric pancreas ablation under MR guidance. METHODS: Two variants of the endoluminal applicator, each containing a distinct array of two independently powered transducers (10 × 10 mm 3...
July 2016: Medical Physics
https://www.readbyqxmd.com/read/27370123/a-gpu-accelerated-monte-carlo-dose-calculation-platform-and-its-application-toward-validating-an-mri-guided-radiation-therapy-beam-model
#17
Yuhe Wang, Thomas R Mazur, Olga Green, Yanle Hu, Hua Li, Vivian Rodriguez, H Omar Wooten, Deshan Yang, Tianyu Zhao, Sasa Mutic, H Harold Li
PURPOSE: The clinical commissioning of IMRT subject to a magnetic field is challenging. The purpose of this work is to develop a GPU-accelerated Monte Carlo dose calculation platform based on penelope and then use the platform to validate a vendor-provided MRIdian head model toward quality assurance of clinical IMRT treatment plans subject to a 0.35 T magnetic field. METHODS: penelope was first translated from fortran to c++ and the result was confirmed to produce equivalent results to the original code...
July 2016: Medical Physics
https://www.readbyqxmd.com/read/27362636/image-driven-model-based-3d-abdominal-motion-estimation-for-mr-guided-radiotherapy
#18
Bjorn Stemkens, Rob H N Tijssen, Baudouin Denis de Senneville, Jan J W Lagendijk, Cornelis A T van den Berg
Respiratory motion introduces substantial uncertainties in abdominal radiotherapy for which traditionally large margins are used. The MR-Linac will open up the opportunity to acquire high resolution MR images just prior to radiation and during treatment. However, volumetric MRI time series are not able to characterize 3D tumor and organ-at-risk motion with sufficient temporal resolution. In this study we propose a method to estimate 3D deformation vector fields (DVFs) with high spatial and temporal resolution based on fast 2D imaging and a subject-specific motion model based on respiratory correlated MRI...
July 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27224231/apparent-diffusion-coefficient-and-dynamic-contrast-enhanced-magnetic-resonance-imaging-in-pancreatic-cancer-characteristics-and-correlation-with-histopathologic-parameters
#19
Wanling Ma, Na Li, Weiwei Zhao, Jing Ren, Mengqi Wei, Yong Yang, Yingmei Wang, Xin Fu, Zhuoli Zhang, Andrew C Larson, Yi Huan
OBJECTIVE: To clarify diffusion and perfusion abnormalities and evaluate correlation between apparent diffusion coefficient (ADC), MR perfusion and histopathologic parameters of pancreatic cancer (PC). METHODS: Eighteen patients with PC underwent diffusion-weighted imaging and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Parameters of DCE-MRI and ADC of cancer and non-cancerous tissue were compared. Correlation between the rate constant that represents transfer of contrast agent from the arterial blood into the extravascular extracellular space (K, volume of the extravascular extracellular space per unit volume of tissue (Ve), and ADC of PC and histopathologic parameters were analyzed...
September 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27132114/test-retest-reliability-of-3d-epi-mr-elastography-of-the-pancreas
#20
H An, Y Shi, Q Guo, Y Liu
AIM: To determine the repeatability of three-dimensional echo planar imaging magnetic resonance (MR) elastography (3D EPI MRE) for assessing pancreatic stiffness in healthy volunteers, patients with chronic pancreatitis, and patients with pancreatic ductal adenocarcinoma (PDAC). MATERIALS AND METHODS: 3D EPI MRE was used to assess pancreatic stiffness in five healthy volunteers, and five and three patients with histopathologically confirmed chronic pancreatitis and PDAC, respectively...
October 2016: Clinical Radiology
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