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https://www.readbyqxmd.com/read/28150798/fermi-level-and-bands-offsets-determination-in-insulating-ga-mn-n-gan-structures
#1
L Janicki, G Kunert, M Sawicki, E Piskorska-Hommel, K Gas, R Jakiela, D Hommel, R Kudrawiec
The Fermi level position in (Ga,Mn)N has been determined from the period-analysis of GaN-related Franz-Keldysh oscillation obtained by contactless electroreflectance in a series of carefully prepared by molecular beam epitaxy GaN/Ga1-xMnxN/GaN(template) bilayers of various Mn concentration x. It is shown that the Fermi level in (Ga,Mn)N is strongly pinned in the middle of the band gap and the thickness of the depletion layer is negligibly small. For x > 0.1% the Fermi level is located about 1.25-1.55 eV above the valence band, that is very close to, but visibly below the Mn-related Mn(2+)/Mn(3+) impurity band...
February 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28143689/reversible-brain-atrophy-in-glutaric-aciduria-type-1
#2
Yurika Numata-Uematsu, Osamu Sakamoto, Yosuke Kakisaka, Yukimune Okubo, Yoshitsugu Oikawa, Natsuko Arai-Ichinoi, Shigeo Kure, Mitsugu Uematsu
Glutaric aciduria type 1 (GA1) is a rare metabolic disorder caused by a deficiency of glutaryl-CoA dehydrogenase. The typical clinical onset features an acute encephalopathic crisis developed in early childhood, causing irreversible striatal injury. Recently, tandem mass spectrometry of spots of dried blood has allowed pre-symptomatic detection of GA1 in newborns. Early treatment can prevent irreversible neurological injury. We report the case of a girl with GA1 who exhibited a characteristic reversible change upon brain magnetic resonance imaging (MRI)...
January 28, 2017: Brain & Development
https://www.readbyqxmd.com/read/28096969/dendrosomal-nanocurcumin-and-p53-overexpression-synergistically-trigger-apoptosis-in-glioblastoma-cells
#3
Reihaneh Keshavarz, Babak Bakhshinejad, Sadegh Babashah, Narges Baghi, Majid Sadeghizadeh
OBJECTIVES: Glioblastoma is the most lethal tumor of the central nervous system. Here, we aimed to evaluate the effects of exogenous delivery of p53 and a nanoformulation of curcumin called dendrosomal curcumin (DNC), alone and in combination, on glioblastoma tumor cells. MATERIALS AND METHODS: MTT assay was exploited to measure the viability of U87-MG cells against DNC treatment. Cells were separately subjected to DNC treatment and transfected with p53-containing vector and then were co-exposed to DNC and p53 overexpression[A GA1][B2]...
December 2016: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28065924/gibberellins-regulate-iron-deficiency-response-by-influencing-iron-transport-and-translocation-in-rice-seedlings-oryza-sativa
#4
Baolan Wang, Haifang Wei, Zhen Xue, Wen-Hao Zhang
BACKGROUND AND AIMS: Gibberellins (GAs) are a class of plant hormones with diverse functions. However, there has been little information on the role of GAs in response to plant nutrient deficiency. METHODS: To evaluate the roles of GAs in regulation of Fe homeostasis, the effects of GA on Fe accumulation and Fe translocation in rice seedlings were investigated using wild-type, a rice mutant (eui1) displaying enhnaced endogenous GA concentrations due to a defect in GA deactivation, and transgenic rice plants overexpressing OsEUI KEY RESULTS: Exposure to Fe-deficient medium significantly reduced biomass of rice plants...
January 8, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28062662/disease-causing-mutations-affecting-surface-residues-of-mitochondrial-glutaryl-coa-dehydrogenase-impair-stability-heteromeric-complex-formation-and-mitochondria-architecture
#5
Jessica Schmiesing, Benjamin Lohmöller, Michaela Schweizer, Henning Tidow, Søren W Gersting, Ania C Muntau, Thomas Braulke, Chris Mühlhausen
The neurometabolic disorder glutaric aciduria type 1 (GA1) is caused by mutations in the GCDH gene encoding the mitochondrial matrix protein glutaryl-CoA dehydrogenase (GCDH), which forms homo- and heteromeric complexes. Twenty percent of all pathogenic mutations affect single amino acid residues on the surface of GCDH resulting in a severe clinical phenotype. We report here on heterologous expression studies of 18 missense mutations identified in GA1 patients affecting surface amino acids. Western blot and pulse chase experiments revealed that the stability of half of the GCDH mutants was significantly reduced...
January 5, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28057895/gibberellin-signaling-requires-chromatin-remodeler-pickle-to-promote-vegetative-growth-and-phase-transitions
#6
Jeongmoo Park, Dong-Ha Oh, Maheshi Dassanayake, Khoa Thi Nguyen, Joe Ogas, Giltsu Choi, Tai-Ping Sun
PICKLE (PKL) is an ATP-dependent Chromodomain-Helicase-DNA-binding domain (CHD3) chromatin remodeling enzyme in Arabidopsis thaliana. Previous studies showed that PKL promotes embryonic-to-vegetative transition by inhibiting expression of seed-specific genes during seed germination. The pkl mutants display a low penetrance of the 'pickle root' phenotype with a thick and green primary root that retains embryonic characteristics. The penetrance of this pickle root phenotype in pkl is dramatically increased in GA-deficient conditions...
January 5, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28009157/solar-water-splitting-and-nitrogen-fixation-with-layered-bismuth-oxyhalides
#7
Jie Li, Hao Li, Guangming Zhan, Lizhi Zhang
Hydrogen and ammonia are the chemical molecules that are vital to Earth's energy, environmental, and biological processes. Hydrogen with renewable, carbon-free, and high combustion-enthalpy hallmarks lays the foundation of next-generation energy source, while ammonia furnishes the building blocks of fertilizers and proteins to sustain the lives of plants and organisms. Such merits fascinate worldwide scientists in developing viable strategies to produce hydrogen and ammonia. Currently, at the forefronts of hydrogen and ammonia syntheses are solar water splitting and nitrogen fixation, because they go beyond the high temperature and pressure requirements of methane stream reforming and Haber-Bosch reaction, respectively, as the commercialized hydrogen and ammonia production routes, and inherit the natural photosynthesis virtues that are green and sustainable and operate at room temperature and atmospheric pressure...
December 23, 2016: Accounts of Chemical Research
https://www.readbyqxmd.com/read/27997362/elucidating-the-relationship-between-crystallo-chemistry-and-optical-properties-of-cigs-nanocrystals
#8
Mahshid Ahmadi, Stevin S Pramana, Chris Boothroyd, Yeng Ming Lam
The performance of solar cells fabricated using Cu(In,Ga)(S,Se)2 nanocrystal (NC) inks synthesized using the hot injection method has yielded efficiencies up to 12% recently. The efficiency of these devices is highly dependent on the chemical composition and crystallographic quality of the NCs. The former has been extensively discussed as it can be easily correlated to the optical properties of the film, but detailed crystallographic structure of these NCs has scarcely been discussed and it can influence both the optical and electrical properties...
January 27, 2017: Nanotechnology
https://www.readbyqxmd.com/read/27966463/growth-of-wurtzite-al-x-ga1-x-p-nanowire-shells-and-characterization-by-raman-spectroscopy
#9
Alexander Berg, Magnus Heurlin, Stylianos Tsopanidis, Mats-Erik Pistol, Magnus T Borgström
The phonon energies of AlGaP in wurtzite crystal structure are generally not known, as opposed to their zincblende counterparts, because AlGaP crystallizes in zincblende phase in bulk and thin films structures. However, in nanowires AlGaP can be grown in wurtzite crystal structure. In this work we have grown wurtzite GaP/AlGaP/GaP core-shell nanowires by use of MOVPE. After developing suitable growth conditions, the Al composition was determined by STEM-EDX measurements and the wurtzite AlGaP phonon energies by Raman spectroscopy...
January 20, 2017: Nanotechnology
https://www.readbyqxmd.com/read/27936573/impurity-compensation-effect-induced-by-tin-valence-change-in-%C3%AE-ga1-4sn0-6o3-thin-films
#10
Xiaolong Zhao, Zhenping Wu, Wei Cui, Yusong Zhi, Daoyou Guo, Linghong Li, Weihua Tang
Corundum-structured α-phase Ga1.4Sn0.6O3 thin films have been deposited on m-plane Al2O3(300) substrates using laser molecular beam epitaxy technology. With increasing of the oxygen partial pressure, the crystal lattice of Ga1.4Sn0.6O3 films expands due to tin ions valence changes from Sn(4+) to Sn(2+). The resistivity of the film deposited under 3 × 10(-5) Pa is 3.54 × 10(4) Ω·cm, which decreases by about 2 orders of magnitude than that fabricated under 3 × 10(-1) Pa. The mixture valence of Sn(2+) and Sn(4+) ions leads to the impurity altitude compensation effect...
December 27, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27878724/production-of-recombinant-polypeptides-containing-one-ga-module-and-analysis-of-their-ability-to-bind-to-human-albumin
#11
E A Bormotova, T V Gupalova
Surface proteins of many bacterial species interact with human serum albumin (HSA) via a special region of amino acid sequence termed GA module. For instance, surface peptostreptococcal albumin-binding protein of anaerobic bacteria Peptostreptococcus magnus contains one HSA-binding GA-module. Protein G from group G and C Streptococcus strains isolated from humans has HSA-binding region consisting of three GA-modules. HSA-binding protein containing two GA-modules was found in strains of group G Streptococcus of animal origin...
November 2016: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27858203/enhanced-fucosylation-of-ga1-in-the-digestive-tracts-of-x-ray-irradiated-mice
#12
Masao Iwamori, Kyoko Tanaka, Shigeki Adachi, Daisuke Aoki, Taisei Nomura
In mice at 4 days after X-ray-irradiation at 0.5 Gy/min for 16 min, the tissue weights of immune organs, i.e., thymus and spleen, were decreased due to injury to lymphocytes by the X-rays. The resulting immunosuppressive condition allowed the growth of lactobacilli, i.e., L. murinus, which contained LacβTH-DG and possessed the ability to induce transcription of the fucosyltransferase gene for synthesis of FGA1. LacβTH-DG was detected in the jejunal and ileal contents of X-ray-irradiated mice, but not in those of control mice, whereas LacTetH-DG of L...
November 18, 2016: Glycoconjugate Journal
https://www.readbyqxmd.com/read/27836184/serological-study-using-glycoarray-for-detecting-antibodies-to-glycolipids-and-glycolipid-complexes-in-immune-mediated-neuropathies
#13
Miyuki Morikawa, Motoi Kuwahara, Rino Ueno, Makoto Samukawa, Yukihiro Hamada, Susumu Kusunoki
We performed a serological investigation using glycoarray in Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and multifocal motor neuropathy (MMN). Antibodies to 10 glycolipids and 45 glycolipid complexes were tested. Anti-GM1/sulfatide and anti-GA1/sulfatide IgG antibodies were common in GBS (20.0% and 19.0%, respectively). Anti-GQ1b/sulfatide IgG antibody was detected in 14.0% of GBS patients. IgG antibodies to antigens containing GQ1b were significantly correlated with ophthalmoplegia in GBS (p<0...
December 15, 2016: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/27790627/microarray-screening-of-guillain-barr%C3%A3-syndrome-sera-for-antibodies-to-glycolipid-complexes
#14
Susan K Halstead, Gabriela Kalna, Mohammad B Islam, Israt Jahan, Quazi D Mohammad, Bart C Jacobs, Hubert P Endtz, Zhahirul Islam, Hugh J Willison
OBJECTIVE: To characterize the patterns of autoantibodies to glycolipid complexes in a large cohort of Guillain-Barré syndrome (GBS) and control samples collected in Bangladesh using a newly developed microarray technique. METHODS: Twelve commonly studied glycolipids and lipids, plus their 66 possible heteromeric complexes, totaling 78 antigens, were applied to polyvinylidene fluoride-coated slides using a microarray printer. Arrays were probed with 266 GBS and 579 control sera (2 μL per serum, diluted 1/50) and bound immunoglobulin G detected with secondary antibody...
December 2016: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/27764111/the-qtl-gnp1-encodes-ga20ox1-which-increases-grain-number-and-yield-by-increasing-cytokinin-activity-in-rice-panicle-meristems
#15
Yuan Wu, Yun Wang, Xue-Fei Mi, Jun-Xiang Shan, Xin-Min Li, Jian-Long Xu, Hong-Xuan Lin
Cytokinins and gibberellins (GAs) play antagonistic roles in regulating reproductive meristem activity. Cytokinins have positive effects on meristem activity and maintenance. During inflorescence meristem development, cytokinin biosynthesis is activated via a KNOX-mediated pathway. Increased cytokinin activity leads to higher grain number, whereas GAs negatively affect meristem activity. The GA biosynthesis genes GA20oxs are negatively regulated by KNOX proteins. KNOX proteins function as modulators, balancing cytokinin and GA activity in the meristem...
October 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27745773/is-the-inactivation-of-dentin-proteases-by-crosslinkers-reversible
#16
Roda Seseogullari-Dirihan, Mustafa Murat Mutluay, David H Pashley, Arzu Tezvergil-Mutluay
OBJECTIVE: Inactivation of dentin proteases by crosslinkers has been suggested as a way to prevent the degradation of dentin collagen in the hybrid layer. However, it is not known if the inhibition is reversible. The aim of this study was to evaluate the inactivation effect of various crosslinkers on dentin protease activity over a period of 6 months. METHODS: Demineralized dentin beams (1×2×6mm, n=10/group) were treated with (1) 1% glutaraldehyde (GA1), (2) 5% glutaraldehyde (GA5), (3) 1% grape seed extract (GS1), (4) 5% grape seed extract (GS5), (5) 10% sumac berry extract (S), (6) 20μM curcumin (CR20), and (7) 200μM curcumin (CR200) for 5min...
October 10, 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/27721133/gibberellins-producing-bacillus-methylotrophicus-ke2-supports-plant-growth-and-enhances-nutritional-metabolites-and-food-values-of-lettuce
#17
Ramalingam Radhakrishnan, In-Jung Lee
The nutritional quality of green leafy vegetables can be enhanced by application of plant beneficial micro-organisms. The present study was aimed to increase the food values of lettuce leaves by bacterial treatment. We isolated bacterial strain KE2 from Kimchi food and identified as Bacillus methylotrophicus by phylogenetic analysis. The beneficial effect of B. methylotrophicus KE2 on plants was confirmed by increasing the percentage of seed germination of Lactuca sativa L., Cucumis melo L., Glycine max L...
December 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27718313/abscisic-acid-regulates-seed-germination-of-vellozia-species-in-response-to-temperature
#18
B C Vieira, E M Bicalho, S Munné-Bosch, Q S Garcia
The relationship between the phytohormones, gibberellin (GA) and abscisic acid (ABA) and light and temperature on seed germination is still not well understood. We aimed to investigate the role of the ABA and GA on seed germination of Vellozia caruncularis, V. intermedia and V. alutacea in response to light/dark conditions on different temperature. Seeds were incubated in GA (GA3 or GA4 ) or ABA and their respective biosynthesis inhibitors (paclobutrazol - PAC, and fluridone - FLU) solutions at two contrasting temperatures (25 and 40 °C)...
October 8, 2016: Plant Biology
https://www.readbyqxmd.com/read/27713528/heat-induced-phytohormone-changes-are-associated-with-disrupted-early-reproductive-development-and-reduced-yield-in-rice
#19
Chao Wu, Kehui Cui, Wencheng Wang, Qian Li, Shah Fahad, Qiuqian Hu, Jianliang Huang, Lixiao Nie, Shaobing Peng
Heat stress causes morphological and physiological changes and reduces crop yield in rice (Oryza sativa). To investigate changes in phytohormones and their relationships with yield and other attributes under heat stress, four rice varieties (Nagina22, Huanghuazhan, Liangyoupeijiu, and Shanyou 63) were grown in pots and subjected to three high temperature treatments plus control in temperature-controlled greenhouses for 15 d during the early reproductive phase. Yield reductions in Nagina22, Huanghuazhan, and Liangyoupeijiu were attributed to reductions in spikelet fertility, spikelets per panicle, and grain weight...
October 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27672653/clinical-and-mutational-analysis-of-the-gcdh-gene-in-malaysian-patients-with-glutaric-aciduria-type-1
#20
Siti Aishah Abdul Wahab, Yusnita Yakob, Nor Azimah Abdul Azize, Zabedah Md Yunus, Leong Huey Yin, Mohd Khairul Nizam Mohd Khalid, Ngu Lock Hock
Glutaric aciduria type 1 (GA1) is an autosomal recessive metabolic disorder caused by deficiency of glutaryl-CoA dehydrogenase enzyme encoded by the GCDH gene. In this study, we presented the clinical and molecular findings of seven GA1 patients in Malaysia. All the patients were symptomatic from infancy and diagnosed clinically from large excretion of glutaric and 3-hydroxyglutaric acids. Bidirectional sequencing of the GCDH gene revealed ten mutations, three of which were novel (Gln76Pro, Glu131Val, and Gly390Trp)...
2016: BioMed Research International
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