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Dental Renal

Sarah Sallon, Yahav Dory, Yazeed Barghouti, Tsewang Tamdin, Rigzin Sangmo, Jamyang Tashi, Sonam Yangdon, Tenzin Yeshi, Tsetan Sadutshang, Michal Rotenburg, Elinor Cohen, Yehudit Harlavan, Galit Sharabi, Tali Bdolah-Abram
Mercury an important therapeutic substance in Tibetan Medicine undergoes complex "detoxification" prior to inclusion in multi-ingredient formulas. In an initial cross-sectional study, patients taking Tibetan Medicine for various conditions were evaluated for mercury toxicity. Two groups were identified: Group 1, patients taking " TSOTHEL: " the most important detoxified mercury preparation and Group 2, patients taking other mercury preparations or mercury free Tibetan Medicine. Atomic fluorescence spectrometry of Tibetan Medicine showed mercury consumption 130 µg/kg/day (Group 1) and 30 µg/kg/day (Group 2) (P ≤ 0...
October 13, 2016: Experimental Biology and Medicine
M Muñoz-Corcuera, L Ramírez-Martínez-Acitores, R-M López-Pintor, E Casañas-Gil, G Hernández-Vallejo
Dabigatran is a newly commercialized drug that is replacing other anticoagulants in the prevention of venous thromboembolism, stroke and systemic arterial valve embolism. It acts directly on thrombin presenting in a dynamic and predictable way, which does not require monitoring these patients. Therefore, we consider the need to assess whether their use increases the risk of bleeding involved before any dental treatment. _Material and Methods: We performed a systematic review with a bibliographic search in PubMed/Medline along with the Cochrane Library...
October 1, 2016: Medicina Oral, Patología Oral y Cirugía Bucal
Fahimeh Rezazadeh, Abdollah Bazargani, Jamshid Roozbeh-Shahroodi, Ali Pooladi, Peyman Arasteh, Khosro Zamani
INTRODUCTION: Diabetes is associated with higher rates of caries, on the other hand some studies have shown that renal failure can be protective against dental caries. OBJECTIVES: In this study we compared oral Lactobacillus and Streptococcus mutans between diabetic dialysis and non-diabetic dialysis patients and the normal population. PATIENTS AND METHODS: During November 2014 to January 2014, 85 people that referred to our medical care center entered the study...
2016: Journal of Renal Injury Prevention
Cong Wang, Ken Takeda, Masahiro Shiba, Hitoshi Takayama, Satoru Munakata
A 71-year-old woman underwent left radical nephrectomy for renal cell carcinoma (clear cell carcinoma, pT1bN0M0) ten years previously. She noticed a tumor on the tip of her tongue and was admitted for dental and oral surgery. The tumor was about 10 mm in size, and tumor resection was done. It was pathologically diagnosed as clear cell carcinoma, which was metastasis of renal cell carcinoma. Computer tomography scan during the same period revealed left hilar lymph node and bilateral lung metastases. We chose to use sunitinib as the treatment for the metastases...
August 2016: Hinyokika Kiyo. Acta Urologica Japonica
Yazan Hassona, Najla Kasabreh, Hanin Hammoudeh, Crispian Scully
Bardet Biedl syndrome is a rare autosomal recessive disorder with variable clinical presentation and challenging diagnosis. Recognition of orofacial features might help in the diagnosis. Dental management of affected patients might be complicated by renal, cardiac, metabolic, neurosensory, and cognitive defects.
August 29, 2016: Special Care in Dentistry
R Cholakova, Petia Pechalova, E Kapon
UNLABELLED: Sagliker syndrome characterized with uglifying the appearance of the face due to secondary hyperparathyroidism in patients with chronic renal failure receiving dialysis long time ago. The aim of the study was to identify any patients with Sagliker syndrome among the 78 patients receiving dialysis at the Dialysis ward, University Hospital "St. George", Plovdiv, Bulgaria. RESULTS: Four patients metthe criteria for Sagliker syndrome: chronic renal insufficiency, secondary hyperparathyroidism, short stature, severe changes in the skull and jaw that lead to festoon-like uglifying face, dental abnormalities, "brown" tumors, deformations of the phalanges of the fingers, psychological diseases and depression...
July 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
Gerhard Schmalz, Anne Kauffels, Otto Kollmar, Jan E Slotta, Radovan Vasko, Gerhard A Müller, Rainer Haak, Dirk Ziebolz
BACKGROUND: Aim of this single center cross-sectional study was to investigate oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis (HD) and after kidney transplantation (KT). METHODS: Patients undergoing HD for end-stage renal failure and after KT were investigated. Oral health behavior was recorded using a standardized questionnaire, e.g. dental behavior, tooth brushing, oral hygiene aids. Oral investigation included screening of oral mucosa, dental findings (DMF-T) and periodontal situation (Papilla bleeding index [PBI] periodontal probing depth [PPD] and clinical attachment loss [CAL])...
2016: BMC Oral Health
Jeremiah Sturgill, Scott Howell, Maureen Munnelly Perry, Hemali Kothari
RATIONALE/BACKGROUND: Approximately 14% of Americans are living with chronic kidney disease (CKD). The prevalence of end-stage renal disease (ESRD), the result of progressing CKD continues to rise by 21,000 per year. There are no updated, evidence-based antibiotic prophylaxis guidelines for patients with renal disease undergoing dental treatment. The most recent was a scientific statement from the American Heart Association (AHA) in 2003. Presented in three parts, the goal of the first part of this study is to determine the current protocol being used to treat renal patients at U...
August 8, 2016: Special Care in Dentistry
K Majchrzak, E Mierzwinska-Nastalska, A Chmura, A Kwiatkowski, L Paczek, G Mlynarczyk, K Szymanek-Majchrzak
BACKGROUND: Removable dentures improve function and aesthetics of masticatory organ. Their proper scheme of use and hygiene procedures have an impact on biofilm formation. Microorganisms in biofilm are often resistant to many antibiotics and may pose a potential threat to patients treated with organ transplant. The study provided for evaluation of dental prostheses hygiene standards with reference to staphylococcal microflora in kidney transplant recipients. METHODS: The study involved 62 patients with removable prostheses...
June 2016: Transplantation Proceedings
Scott Howell, Maureen Munnelly Perry, Nipa Patel
RATIONALE/BACKGROUND: Approximately 14% of Americans are living with chronic kidney disease (CKD). The prevalence of end stage renal disease (ESRD), the result of progressing CKD continues to rise by 21,000 per year.Currently the only antibiotic prophylaxis guidelines for patients with end-stage renal disease undergoing dental treatment were published by the AHA in 2003. Presented in three parts, the first part of this study found no consistent protocols amongst U.S. dental schools. The goal of the second part of the project was to determine the current protocol being used to treat ESRD patients at accredited U...
August 5, 2016: Special Care in Dentistry
Danielle Ní Chróinín, Adrian Montalto, Shahrzad Jahromi, Nicholas Ingham, Alexander Beveridge, Peter Foltyn
OBJECTIVES: To investigate oral health status and abnormalities in older adults admitted acutely to the hospital and explore the association with common medical comorbidities. DESIGN: Cross-sectional study. SETTING: Hospital. PARTICIPANTS: All individuals aged 70 and older (mean age 84.4, 61.4% female) admitted to a geriatric service over 3 months (N = 202). MEASUREMENTS: In-person assessment using the Oral Health Assessment Tool (OHAT) (range 0-2, 2 = poorest) for lips, tongue, gums and soft tissue, saliva, teeth, dentures, oral cleanliness, and dental pain...
August 2016: Journal of the American Geriatrics Society
Evgeny N Suspitsin, Evgeny N Imyanitov
Bardet-Biedl syndrome (BBS) is a rare autosomal recessive genetic disorder. It is characterized by heterogeneous clinical manifestations including primary features of the disease (rod-cone dystrophy, polydactyly, obesity, genital abnormalities, renal defects, and learning difficulties) and secondary BBS characteristics (developmental delay, speech deficit, brachydactyly or syndactyly, dental defects, ataxia or poor coordination, olfactory deficit, diabetes mellitus, congenital heart disease, etc.); most of these symptoms may not be present at birth but appear and progressively worsen during the first and second decades of life...
May 2016: Molecular Syndromology
José Alcides Arruda, Eugênia Figueiredo, Pâmella Álvares, Luciano Silva, Leorik Silva, Antônio Caubi, Marcia Silveira, Ana Paula Sobral
Cervical necrotizing fasciitis is an unusual infection characterized by necrosis of the subcutaneous tissue and fascial layers. Risk factors for the development of necrotizing fasciitis include diabetes mellitus, chronic renal disease, peripheral vascular disease, malnutrition, advanced age, obesity, alcohol abuse, intravenous drug use, surgery, and ischemic ulcers. This report presents a case of necrotizing fasciitis in the cervical area caused by dental extraction in a 73-year-old woman. Cervical necrotizing fasciitis in geriatric patient is rare, and even when establishing the diagnosis and having it timely treated, the patient can suffer irreversible damage or even death...
2016: Case Reports in Dentistry
J Hitzeroth, N Beckett, P Ntuli
Although infective endocarditis (IE) is relatively uncommon, it remains an important clinical entity with a high in-hospital and 1-year mortality. It is most commonly caused by viridans streptococci. Staphylococcus aureus is responsible for a malignant course of IE and often requires early surgery to eradicate. Other rarer causes are various bacilli, including the HACEK (Haemophilus, Actinobacillus,Cardiobacterium, Eikenella and Kingella spp.) group of organisms and fungi. The clinical presentation varies. Patients may present with a nonspecific illness, valve dysfunction, heart failure (HF) and symptoms due to peripheral embolisation...
February 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Jillian Casey, Allan Jenkinson, Alex Magee, Sean Ennis, Ahmad Monavari, Andrew Green, Sally A Lynch, Ellen Crushell, Joanne Hughes
We report a female child from an Irish Traveller family presenting with severe intellectual disability, dysmorphic features, renal anomalies, dental caries and cyclical vomiting. Current health issues include global developmental delay, mild concentric left ventricular hypertrophy, dental malocclusion and caries and a single duplex left kidney. The proband and her mother also have multiple epiphyseal dysplasia. Whole-exome sequencing was performed to identify the underlying genetic cause. DNA from the proband was enriched with the Agilent Sure Select v5 Exon array and sequenced on an Illumina HiSeq...
October 2016: Clinical Dysmorphology
Aynur Gulcan, Erim Gulcan, Mustafa Keles, Esin Aktas
We aimed to investigate the frequency of oral yeast colonization (OYC) and the risk factors for patients who received continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis (HD) or were renal transplant recipients (RTRs). The patients admitted to the Nephrology Clinic at Ataturk University Medical School from January through April 2013 were included in the study. A questionnaire about risk factors was filled out, and swab cultures were taken from the tongue surface of each participant. OYC was detected in 32...
June 2016: Comparative Immunology, Microbiology and Infectious Diseases
Ursula Reyes, Ann Eshenaur Spolarich, Phuu Pwint Han
Candidates and recipients of kidney transplants are at high risk for oral infections due to systemic co-morbidities, and disease and drug-induced immunosuppression. Developing oral infections while on the waiting list can jeopardize candidacy for receiving a kidney, and post-operatively increases the chance for organ rejection. Therefore, it is imperative to minimize oral disease risks in this population. A comprehensive, oral preventive care protocol is presented to guide dental professionals with patient management throughout the process of care...
April 2016: Journal of Dental Hygiene: JDH
A Ouanounou, D A Haas
Pregnancy is accompanied by various physiological and physical changes, including those found in the cardiovascular, respiratory, gastrointestinal, renal and haematological systems. These alterations in the pregnant patient may potentially affect drug pharmacokinetics. Also, pharmacotherapy presents a unique matter due to the potential teratogenic effects of certain drugs. Although medications prescribed by dentists are generally safe during pregnancy, some modifications may be needed. In this article we will discuss the changes in the physiology during pregnancy and its impact on drug therapy...
April 22, 2016: British Dental Journal
Takashi Hitosugi, Masanori Tsukamoto, Shigeki Fujiwara, Takeshi Yokoyama
Dandy-Walker syndrome (DWS) is characterized by perfect or partial defect of the cerebellum vermis and cystic dilatation of the posterior fossa communicating with the fourth ventricle. Common clinical signs are mental retardation, cerebellar ataxia, and those of increased intracranial pressure (ICP). Associated congenital anomalies are craniofacial, cardiac, renal, and skeletal abnormalities. We experienced a case of intravenous sedation and six times of "the same day" general anesthesia for a school-aged boy (10-13 years old) with DWS and hypodentinogenesis...
March 2016: Masui. the Japanese Journal of Anesthesiology
Francesca Garuti, Vittoria Camelli, Luca Spinardi, Laura Bucci, Franco Trevisani
INTRODUCTION: Sorafenib is an oral multiple tyrosine kinase inhibitor and is currently the only evidence-based treatment recommended for advanced hepatocellular carcinoma. We report a case of osteonecrosis of the jaw that occurred during sorafenib therapy in a patient with advanced hepatocellular carcinoma not treated with bisphosphonates or other antiangiogenic drugs. METHODS: A systematic search in PubMed yielded some cases of osteonecrosis of the jaw in patients treated with antiangiogenic agents, alone or in combination with bisphosphonates, for metastatic renal cell carcinoma...
April 9, 2016: Tumori
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