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https://www.readbyqxmd.com/read/28109012/the-impact-of-a-soiled-airway-on-intubation-success-in-the-emergency-department-when-using-the-glidescope-or-the-direct-laryngoscope
#1
John C Sakles, G Judson Corn, Patrick Hollinger, Brittany Arcaris, Asad E Patanwala, Jarrod M Mosier
BACKGROUND: To determine the impact of a soiled airway on first pass success when using the GlideScope video laryngoscope or the direct laryngoscope for intubation in the emergency department. METHODS: Data were prospectively collected on all patients intubated in an academic emergency department from July 1, 2007 to June 30, 2016. Patients ≥18 years of age, who underwent rapid sequence intubation with the GlideScope or the direct laryngoscope were included in the analysis...
January 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28108942/compartmentalized-culture-of-perivascular-stroma-and-endothelial-cells-in-a-microfluidic-model-of-the-human-endometrium
#2
Juan S Gnecco, Virginia Pensabene, David J Li, Tianbing Ding, Elliot E Hui, Kaylon L Bruner-Tran, Kevin G Osteen
The endometrium is the inner lining of the uterus. Following specific cyclic hormonal stimulation, endometrial stromal fibroblasts (stroma) and vascular endothelial cells exhibit morphological and biochemical changes to support embryo implantation and regulate vascular function, respectively. Herein, we integrated a resin-based porous membrane in a dual chamber microfluidic device in polydimethylsiloxane that allows long term in vitro co-culture of human endometrial stromal and endothelial cells. This transparent, 2-μm porous membrane separates the two chambers, allows for the diffusion of small molecules and enables high resolution bright field and fluorescent imaging...
January 20, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28108902/comparison-of-anterior-segment-measurements-with-lenstar-and-pentacam-in-patients-with-newly-diagnosed-glaucoma
#3
Emine Sen, Merve Inanc, Ufuk Elgin, Pelin Yilmazbas
PURPOSE: To compare anterior segment measurements obtained using the Pentacam; Oculus, HR and the LenStar LS 900 in patients with newly diagnosed glaucoma. METHODS: Patients with ocular hypertension and primary open-angle glaucoma who had been treated with PGA were included in the study. Anterior segment measurements including central corneal thickness (CCT), keratometry, anterior chamber depth (ACD) and white-to-white (WTW) corneal diameter obtained with the optic low-coherent reflectometer (LenStar LS-900, Haag-Streit AG, Switzerland) and with the Scheimpflug system (Pentacam; Oculus, HR) were compared...
January 21, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28108819/preemptive-treatment-with-xonrid%C3%A2-a-medical-device-to-reduce-radiation-induced-dermatitis-in-head-and-neck-cancer-patients-receiving-curative-treatment-a-pilot-study
#4
Nicola Alessandro Iacovelli, Simona Naimo, Francesca Bonfantini, Anna Cavallo, Paolo Bossi, Carlo Fallai, Emanuele Pignoli, Salvatore Alfieri, Cristiana Bergamini, Federica Favales, Ester Orlandi
PURPOSE: The purpose of this study was to investigate efficacy, safety and tolerability of Xonrid®, a new medical device, in preventing radiation dermatitis associated with head and neck cancer (HNC) radiotherapy (RT). METHODS: In this monocentric, prospective pilot study, adult consecutive HNC patients who were planned to receive curative RT with or without chemotherapy were enrolled. Patients were instructed to apply Xonrid® on the irradiated area during treatment continuing until 2 weeks after the completion of RT or the development of severe skin toxicity...
January 20, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28108686/use-of-mechanical-insufflation-exsufflation-devices-for-airway-clearance-in-subjects-with-neuromuscular-disease
#5
REVIEW
Catherine Auger, Vanessa Hernando, Hubert Galmiche
The aim of this systematic review is to examine the benefit/risk ratio of the use of mechanical insufflation-exsufflation (MI-E) devices for airway clearance in patients with neuromuscular diseases. A search was conducted for relevant studies in MEDLINE, the Cochrane Library, and the Health Technology Assessment Database using the main key words: cough, airway clearance, in-exsufflation. The search limits were studies published in English and French between 1970 and 2014 (literature watch until December 2015)...
February 2017: Respiratory Care
https://www.readbyqxmd.com/read/28108564/technical-details-making-aortic-arch-replacement-a-safe-procedure-using-the-thoraflex%C3%A2-hybrid-prosthesis
#6
REVIEW
Martin Czerny, Bartosz Rylski, Fabian A Kari, Maximilian Kreibich, Julia Morlock, Johannes Scheumann, Stoyan Kondov, Michael Südkamp, Matthias Siepe, Friedhelm Beyersdorf
SummaryThe development of new devices to improve treatment and to explore new indications that have not yet been adequately addressed is a natural consequence of the clinical demand for solutions to as yet unmet needs. The frozen elephant trunk technique was one of the major steps within the last 15 years to improve on existing treatments as well as to explore new indications. The goal of this article is to provide technical details about advances in implantation techniques for the treatment of acute and chronic thoracic aortic pathological conditions...
January 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28108500/ophthalmic-artery-occlusion-after-pipeline-embolization-device-placement-with-reconstitution-of-flow-via-an-endoleak-a-report-of-two-cases
#7
Michael L Adix, Ian A Kaminsky, In Sup Choi
The Pipeline Embolization Device (PED) is a flow diverting stent used in the treatment of a wide variety of intracranial aneurysms. The device differs from traditional stents used in stent-assisted coil embolization in that it has a tighter lattice structure with smaller cell sizes designed specifically to disrupt blood flow into aneurysms rather than only to retain coils within aneurysms. While the PED has been shown to be safe and effective, it has a unique risk profile that includes side branch and perforator vessel occlusion...
January 20, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28108483/measuring-hip-muscle-strength-in-patients-with-femoroacetabular-impingement-and-other-hip-pathologies-a-systematic-review
#8
E Mayne, A Memarzadeh, P Raut, A Arora, V Khanduja
OBJECTIVES: The aim of this study was to systematically review the literature on measurement of muscle strength in patients with femoroacetabular impingement (FAI) and other pathologies and to suggest guidelines to standardise protocols for future research in the field. METHODS: The Cochrane and PubMed libraries were searched for any publications using the terms 'hip', 'muscle', 'strength', and 'measurement' in the 'Title, Abstract, Keywords' field. A further search was performed using the terms 'femoroacetabular' or 'impingement'...
January 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28108422/role-of-microglia-autophagy-in-microglia-activation-after-traumatic-brain-injury
#9
Yichao Jin, Ran Wang, Shaofeng Yang, Xiaohua Zhang, Jiong Dai
OBJECTIVE: Role of microglia autophagy in microglia activation after traumatic brain injury (TBI) remains elusive. Here, we evaluated role of microglia autophagy in microglia activation after traumatic brain injury (TBI) in rats. METHODS: TBI was induced by a fluid percussion TBI device. All rats were killed at 24 h after TBI. The ipsilateral hippocampus in all rats was analyzed with hematoxylin and eosin staining; Immunohistochemistry and western blotting of IBA-1 was used to determine the changes of microglia activation; Double staining of microtubule-associated protein light chain 3 (LC-3), Beclin-1 and IBA-1 was used to assess the changes of microglia autophagy; enzyme-linked immunosorbent assay (ELISA) of tumor necrosis factor receptor-alpha (TNF-α) and interleukin-1β (IL-1β) was used to evaluate the changes of inflammatory responses; terminal deoxynucleoitidyl transferase mediated nick end labeling staining (TUNEL) was used to determine cell death in ipsilateral hippocampus...
January 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28108333/determining-activity-count-cut-points-for-measurement-of-physical-activity-using-the-actiwatch2-accelerometer
#10
Sarah E Neil-Sztramko, Bolette Skjødt Rafn, Carolyn C Gotay, Kristin L Campbell
STUDY OBJECTIVES: Sleep and physical activity are important contributions to many aspects of health. Obtaining accurate, objective measures of both behaviours is critical to health research. The Actiwatch2 is a wrist-worn sleep-monitoring device that has the potential to measure physical activity. Currently, interpretation of the Actiwatch2 physical activity data is limited by a lack of published thresholds for interpreting exercise intensity. This limits the ability to collect information on both behaviours simultaneously using one monitor...
January 17, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28108108/pharmaceuticals-and-personal-care-products-in-plants
#11
REVIEW
Mireia Bartrons, Josep Peñuelas
Pharmaceuticals and personal-care products (PPCPs) derived from agricultural, urban, and industrial areas accumulate in plants at concentrations (ng to μg kg(-1)) that can be toxic to the plants. Importantly, the dietary intake of these PPCP-contaminated plants may also pose a risk to human health, but currently little is known about the fate of PPCPs in plants and their effect on or risk to the ecosystem. In this Opinion article we propose that in-depth research on the use of plants as a monitoring device for assessing the use and environmental presence of PPCPs is warranted...
January 17, 2017: Trends in Plant Science
https://www.readbyqxmd.com/read/28108038/the-effect-of-endotracheal-tubes-versus-laryngeal-mask-airways-on-perioperative-respiratory-adverse-events-in-infants-a-randomised-controlled-trial
#12
Thomas F E Drake-Brockman, Anoop Ramgolam, Guicheng Zhang, Graham L Hall, Britta S von Ungern-Sternberg
BACKGROUND: Perioperative respiratory adverse events (PRAE) are the most common critical incidents in paediatric anaesthesia and occur more often in infants. Use of laryngeal mask airways (LMAs) is associated with reduced PRAE compared with endotracheal tubes in older children (>1 year). We aimed to evaluate the effect of these devices on the incidence of PRAE in infants. METHODS: We did a randomised controlled trial at the Princess Margaret Hospital for Children in Perth (WA, Australia) by recruiting infants (aged 0-12 months) undergoing general (with or without regional or local) anaesthesia with anticipated fentanyl dose 1 μg/kg or lower for minor elective surgery...
January 17, 2017: Lancet
https://www.readbyqxmd.com/read/28107996/the-stability-of-tnt-rdx-and-petn-in-simulated-post-explosion-soils-implications-of-sample-preparation-for-analysis
#13
H A Yu, D A DeTata, S W Lewis, N Nic Daeid
Explosives residues in soils may be a useful source of evidence following the detonation of an improvised explosive device (IED), such as a vehicle-borne IED. Soil samples collected from the vicinity of an explosion scene will often be stored for some time prior to analysis, yet explosives residues in soil samples are susceptible to rapid degradation or transformation. Although some research has assessed the use of different storage temperatures with a view to reducing explosives' degradation over time, further research examining the degradation of explosives in soil when stored under a variety of storage conditions is crucial to determine the optimal sample collection and storage procedures for soil containing explosives residues...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107994/application-of-passive-sampling-devices-based-on-multi-walled-carbon-nanotubes-for-the-isolation-of-selected-pharmaceuticals-and-phenolic-compounds-in-water-samples-possibilities-and-limitations
#14
Aleksandra Jakubus, Magdalena Tyma, Piotr Stepnowski, Monika Paszkiewicz
Nowadays, carbon nanotubes, as commercially available materials, have attracted great attention because of their unique physicochemical properties, especially their strong adsorption abilities. This paper deals with the possibilities and limitations of the application of multi-walled carbon nanotubes as an alternative sorbent in passive sampling devices for the isolation of selected pharmaceuticals and phenolic compounds directly in water samples. Compounds with different properties, including sulfapyridine, sulfamethoxazole, carbamazepine, p-nitrophenol, 17-β-estradiol, 3,5-dichlorophenol and diclofenac were selected as model compounds...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107984/development-and-validation-of-a-fast-micro-extraction-by-packed-sorbent-uhplc-pda-method-for-the-simultaneous-determination-of-linezolid-and-ciprofloxacin-in-human-plasma-from-patients-with-hospital-acquired-pneumonia
#15
Vincenzo Ferrone, Maura Carlucci, Roberto Cotellese, Paolo Raimondi, Annadomenica Cichella, Lorenzo Di Marco, Giuseppe Carlucci
An ultra high-performance liquid chromatographic (UHPLC) method with PDA detection was developed and validated for the simultaneous quantification of linezolid and ciprofloxacin in human plasma and applied in hospital acquired pneumonia patients (HAP). The method uses a semi-automated microextraction by packed sorbent for sample preparation. All parameters in the extraction step (pH, sample volume, sample dilution and number of aspiration - ejection cycles) and in the desorption step (percentage of acetonitrile in the solvent of elution and number of aspirations of elution solvent through the device) were statistically significant when the recovery was used as response...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107980/lab-on-chip-for-liquid-biopsy-loc-lb-based-on-dielectrophoresis
#16
Bobby Mathew, Anas Alazzam, Saud Khashan, Mohammad Abutayeh
This short communication presents the proof-of-concept of a novel dielectrophoretic lab-on-chip for identifying/separating circulating tumor cells for purposes of liquid biopsy. The device consists of a polydimethylsiloxane layer, containing a microchannel, bonded on a glass substrate that holds two sets of planar interdigitated transducer electrodes. The lab-on-chip is operated at a frequency that enables dielectrophoretic force to sort cells, based on type, along the lateral direction. The operating frequency ensures attraction force toward the electrodes on cancer cells and repulsion force toward the center of the microchannel on other cells...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107969/a-new-paper-based-analytical-device-for-detection-of-glucose-6-phosphate-dehydrogenase-deficiency
#17
Phuritat Kaewarsa, Wanida Laiwattanapaisal, Attakorn Palasuwan, Duangdao Palasuwan
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic haemolytic disorder. Most persons with G6PD deficiency are asymptomatic, but exposure to oxidant drugs, such as the anti-malarial drug primaquine, may induce haemolysis, which is commonly found in Asian countries. A reliable test is necessary for diagnosing the deficiency to prevent an acute haemolytic crisis. This study proposes a novel quantitative method to detect G6PD deficiency using paper-based analytical devices (G6PDD-PAD). Wax printing was utilized for fabricating circular reaction zone patterns in paper...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107960/thermal-desorption-modulation-for-comprehensive-two-dimensional-gas-chromatography-using-a-simple-and-inexpensive-segmented-loop-fluidic-interface
#18
Vanessa Mucédola, Luis C S Vieira, Danilo Pierone, Angelo L Gobbi, Ronei J Poppi, Leandro W Hantao
In this study, we introduce a modulation strategy for comprehensive two-dimensional gas chromatography (GC×GC) by using a simple and consumable-free modulator. This "Do-It-Yourself" interface comprised a 1.0m×0.25mm segment of MTX-5 metallic column and a low-cost DC power supply. Thermal desorption modulation (TDM) was attained using a dual-stage heater-based modulator in a novel segmented-loop configuration. TDM was achieved by alternating analyte trapping and thermal desorption. Former process relied on analyte partition to sorbent phase, while latter explored direct resistive heating...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107955/matrix-isolation-with-an-ion-transfer-device-for-interference-free-simultaneous-spectrophotometric-determinations-of-hexavalent-and-trivalent-chromium-in-a-flow-based-system
#19
Shin-Ichi Ohira, Koretaka Nakamura, Mitsuki Chiba, Purnendu K Dasgupta, Kei Toda
Chromium speciation by spectrophotometric determination of hexavalent chromium (Cr(VI)) with diphenylcarbazide (DPC) has several problems. These include: (1) the inability to directly detect trivalent chromium (Cr(III)) with DPC, (2) positive interference in Cr(VI) determination by other metal cations and (3) negative interference by any reducing agent present in the sample. These are addressed with an ion transfer device (ITD) in a flow injection analysis system. We previously developed the ITD for electrodialytic separations...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107953/visual-detection-of-nucleic-acids-based-on-lateral-flow-biosensor-and-hybridization-chain-reaction-amplification
#20
Na Ying, Chuanjing Ju, Zhongyi Li, Wensen Liu, Jiayu Wan
In this study, a new lateral flow nucleic acid biosensor (LFNAB) using hybridization chain reaction (HCR) for signal amplification was developed for visual detection of nucleic acids with high sensitivity and low cost. A "sandwich-type" detection strategy was employed in our design. The sandwich system of capture probe (CP)/target DNA/reporter probe (RP)-HCR complexes was fabricated as the sensing platform. As the initiator strand, reporter probe propagated a chain reaction of hybridization events between the two hairpin probes modified with biotin, and determined whether long nicked DNA polymers were formed...
March 1, 2017: Talanta
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