Marc Vogel, Maximilian Meyer, Jean N Westenberg, Adrian Kormann, Olivier Simon, Roba Salim Hassan Fadlelseed, Markus Kurmann, Rebecca Bröer, Nathalie Devaud, Ulrike Sanwald, Sophie Baumgartner, Hannes Binder, Johannes Strasser, R Michael Krausz, Thilo Beck, Kenneth M Dürsteler, Luis Falcato
BACKGROUND: Heroin-assisted treatment (HAT) is effective for individuals with severe opioid use disorder (OUD) who do not respond sufficiently to other opioid agonist treatments. It is mostly offered with injectable diacetylmorphine (DAM) or DAM tablets creating a barrier for individuals who need the rapid onset of action but are either unable or unwilling to inject, or primarily snort opioids. To explore another route of administration, we evaluated the safety and feasibility of intranasal (IN) DAM...
January 7, 2023: Harm Reduction Journal