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Radiochromic film

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https://www.readbyqxmd.com/read/28715250/the-development-of-technology-for-effective-respiratory-gated-irradiation-using-an-image-guided-small-animal-irradiator
#1
M A Hill, J Thompson, A Kavanagh, I D C Tullis, R G Newman, J Prentice, J Beech, S Gilchrist, S Smart, E Fokas, B Vojnovic
The development of image-guided small animal irradiators represents a significant improvement over standard irradiators by enabling preclinical studies to mimic radiotherapy in humans. The ability to deliver tightly collimated targeted beams, in conjunction with gantry or animal couch rotation, has the potential to maximize tumor dose while sparing normal tissues. However, the current commercial platforms do not incorporate respiratory gating, which is required for accurate and precise targeting in organs subject to respiration related motions that may be up to the order of 5 mm in mice...
July 17, 2017: Radiation Research
https://www.readbyqxmd.com/read/28711183/fast-protocol-for-radiochromic-film-dosimetry-using-a-cloud-computing-web-application
#2
Juan-Francisco Calvo-Ortega, Miquel Pozo, Sandra Moragues, Joan Casals
PURPOSE: To investigate the feasibility of a fast protocol for radiochromic film dosimetry to verify intensity-modulated radiotherapy (IMRT) plans. METHOD AND MATERIALS: EBT3 film dosimetry was conducted in this study using the triple-channel method implemented in the cloud computing application (Radiochromic.com). We described a fast protocol for radiochromic film dosimetry to obtain measurement results within 1h. Ten IMRT plans were delivered to evaluate the feasibility of the fast protocol...
July 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28691256/clinical-usefulness-of-mlcs-in-robotic-radiosurgery-systems-for-prostate-sbrt
#3
Masashi Tomida, Takeshi Kamomae, Junji Suzuki, Yoichi Ohashi, Yoshiyuki Itoh, Hiroshi Oguchi, Takahito Okuda
Stereotactic body radiation therapy (SBRT) using recently introduced multileaf collimators (MLC) is preferred over circular collimators in the treatment of localized prostate cancer. The objective of this study was to assess the clinical usefulness of MLCs in prostate SBRT by comparing the effectiveness of treatment plans using fixed collimators, variable collimators, and MLCs and by ensuring delivery quality assurance (DQA) for each. For each patient who underwent conventional radiation therapy for localized prostate cancer, mock SBRT plans were created using a fixed collimator, a variable collimator, and an MLC...
July 10, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28671885/effects-of-the-metallic-port-in-tissue-expanders-on-dose-distribution-in-postmastectomy-radiotherapy-a-tridimensional-experimental-model-of-dosimetry-in-breast-reconstruction
#4
Marcelo Felix da Silva, Harley Francisco de Oliveira, Leandro Frederich Borges, Helio Humberto Angotti Carrara, Jayme Adriano Farina
The purpose of this research was to develop an experimental model of dosimetry using a breast phantom and evaluate the effects of the metallic port in tissue expanders on dose distribution in postmastectomy radiotherapy. Dose distribution was assessed using an experimental acrylic dosimetry simulator in the absence and presence of a metallic disc (MD), which is similar to that used in tissue expanders containing a magnetic port, by collecting coronal and sagittal radiochromic films. Dosimetry film analysis did not show any changes in dose distribution, except for a MD shadow in the sagittal film where the dose distribution rate was on average 14% lower than in other areas...
June 1, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28666767/towards-breast-cancer-rotational-radiotherapy-with-synchrotron-radiation
#5
Francesca Di Lillo, Giovanni Mettivier, Antonio Sarno, Roberta Castriconi, Paolo Russo
PURPOSE: We performed the first investigations, via measurements and Monte Carlo simulations on phantoms, of the feasibility of a new technique for synchrotron radiation rotational radiotherapy for breast cancer (SR(3)T). METHODS: A Monte Carlo (MC) code based on Geant4 toolkit was developed in order to simulate the irradiation with the SR(3)T technique and to evaluate the skin sparing effect in terms of centre-to-periphery dose ratio at different energies in the range 60-175keV...
June 27, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28620561/patient-specific-qa-of-spot-scanning-proton-beams-using-radiochromic-film
#6
Maria F Chan, Chin-Cheng Chen, Chengyu Shi, Jingdong Li, Xiaoli Tang, Xiang Li, Dennis Mah
Radiochromic film for spot-scanning QA provides high spatial resolution and efficiency gains from one-shot irradiation for multiple depths. However, calibration can be a tedious procedure which may limit widespread use. Moreover, since there may be an energy dependence, which manifests as a depth dependence, this may require additional measurements for each patient. We present a one-scan protocol to simplify the procedure. A calibration using an EBT3 film, exposed by a 6-level step-wedge plan on a Proteus(®)PLUS proton system (IBA, Belgium), was performed at depths of 18, 20, 24cm using Plastic Water(®) (CIRS, Norfolk, VA)...
May 2017: International journal of medical physics, clinical engineering and radiation oncology
https://www.readbyqxmd.com/read/28578699/treating-lung-cancer-with-dynamic-conformal-arc-therapy-a-dosimetric-study
#7
Primož Peterlin, Karmen Stanič, Ignasi Méndez, Andrej Strojnik
BACKGROUND: Lung cancer patients are often in poor physical condition, and a shorter treatment time would reduce their discomfort. Dynamic conformal arc therapy (DCAT) offers a shorter treatment time than conventional 3D conformal radiotherapy (3D CRT) and is usually available even in departments without inverse planning possibilities. We examined its suitability as a treatment modality for lung cancer patients. METHODS: On a cohort of 35 lung cancer patients, relevant dosimetric parameters were compared in respective DCAT and 3D CRT treatment plans...
June 2, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28574219/optimization-of-the-dosimetric-leaf-gap-for-use-in-planning-vmat-treatments-of-spine-sabr-cases
#8
Nigel D Middlebrook, Bess Sutherland, Tanya Kairn
The dosimetric leaf gap (DLG) is a beam configuration parameter used in the Varian Eclipse treatment planning system, to model the effects of rounded MLC leaf ends. Measuring the DLG using the conventional sliding-slit technique has been shown to be produce questionable results for some volumetric modulated arc therapy (VMAT) treatments. This study therefore investigated the use of radiochromic film measurements to optimize the DLG specifically for the purpose of producing accurate VMAT plans using a flattening-filter-free (FFF) beam, for use in treating vertebral targets using a stereotactic (SABR, also known as SBRT) fractionation schedule...
June 2, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28574149/measurement-of-uv-emission-from-a-diffusing-optical-fiber-using-radiochromic-film
#9
David Welch, Henry M Spotnitz, David J Brenner
Analysis of the emission pattern from optical diffuser tips is vital to their usage in biomedical applications, especially as they find growing functionality beyond established phototherapy techniques. The use of ultraviolet radiation with diffuser tips increases the need to accurately characterize these devices, both for effective application and to avoid potentially dangerous exposure conditions. This work presents a new method to capture the diffusion pattern at a high resolution through the use of radiochromic film...
June 2, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28556241/carbon-and-oxygen-minibeam-radiation-therapy-an-experimental-dosimetric-evaluation
#10
Immaculada Martínez-Rovira, Wilfredo González, Stephan Brons, Yolanda Prezado
PURPOSE: To perform dosimetric characterization of a minibeam collimator in both carbon and oxygen ion beams to guide optimal set up geometry and irradiation for future radiobiological studies using these beams. METHODS: Carbon and oxygen minibeams were generated using a prototype tungsten multislit collimator presenting line apertures 700 μm wide, which are spaced 3500 μm centre-to-centre distance apart. Several radiation beam spots generated the desired field size of 15X15 mm(2) and production of a 50 mm long spread out Bragg peak (SOBP) centered at 80 mm-depth in water...
May 29, 2017: Medical Physics
https://www.readbyqxmd.com/read/28532617/first-french-experiences-of-total-body-irradiations-using-helical-tomotherapy-%C3%A2
#11
R Sun, X Cuenca, R Itti, S Nguyen Quoc, J-P Vernant, J-J Mazeron, C Jenny, M Chea
PURPOSE: Dynamic conformal radiotherapy with helical TomoTherapy(®) (HT) offers a more quantitative paradigm for total body irradiation. Treatment planning, delivery, dose verification of the first French experiences of total body irradiation using helical TomoTherapy(®) are presented. MATERIALS AND METHODS: Patients planned for total body irradiation at our institution from February 2012 to May 2013 were reported. Total body irradiation consisted in a single fraction of 2Gy...
May 19, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28513854/verification-of-dose-profiles-generated-by-the-convolution-algorithm-of-the-gamma-knife-%C3%A2-radiosurgery-planning-system
#12
Hyun-Tai Chung, Jeong-Hoon Park, Kook Jin Chun
PURPOSE: A convolution algorithm that takes into account electron-density inhomogeneity was recently introduced to calculate dose distributions for the Gamma Knife (GK) Perfexion(™) treatment planning program. The accuracies of the dose distributions computed using the convolution method were assessed using an anthropomorphic phantom and film dosimetry. METHODS: Absorbed-dose distributions inside a phantom (CIRS Radiosurgery Head Phantom, Model 605) were calculated using the convolution method of the GK treatment-planning software (Leksell Gamma Plan(®) version 10...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28478867/targeting-accuracy-of-single-isocenter-intensity-modulated-radiosurgery-for-multiple-lesions
#13
J F Calvo-Ortega, M Pozo, S Moragues, J Casals
To investigate the targeting accuracy of intensity-modulated SRS (IMRS) plans designed to simultaneously treat multiple brain metastases with a single isocenter. A home-made acrylic phantom able to support a film (EBT3) in its coronal plane was used. The phantom was CT scanned and three coplanar small targets (a central and two peripheral) were outlined in the Eclipse system. Peripheral targets were 6 cm apart from the central one. A reference IMRS plan was designed to simultaneously treat the three targets, but only a single isocenter located at the center of the central target was used...
May 3, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28457741/commissioning-of-applicator-guided-stereotactic-body-radiation-therapy-boost-with-high-dose-rate-brachytherapy-for-advanced-cervical-cancer-using-radiochromic-film-dosimetry
#14
Saad Aldelaijan, Shada Wadi-Ramahi, Ahmad Nobah, Belal Moftah, Slobodan Devic, Noha Jastaniyah
PURPOSE: To describe an EBT3 GAFCHROMIC film-based dosimetry method to be used in commissioning of a combined HDR brachytherapy (HDRB) and stereotactic body radiation therapy (SBRT) boost for treatment of advanced cervical cancer involving extensive residual disease after external beam treatment. METHODS AND MATERIALS: A cube phantom was designed to firmly fit an intrauterine tandem applicator and EBT3 radiochromic film pieces. A high-risk clinical target volume (CTVHR, Total) was contoured with an extended arm at one side...
April 27, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28436134/measurement-of-skin-surface-dose-distributions-in-radiation-therapy-using-poly-vinyl-alcohol-cryogel-dosimeters
#15
Molham M Eyadeh, Marcin Wierzbicki, Kevin R Diamond
In external beam radiation therapy (EBRT), skin dose measurement is important to evaluate dose coverage of superficial target volumes. Treatment planning systems (TPSs) are often inaccurate in this region of the patient, so in vivo measurements are necessary for skin surface dose estimation. In this work, superficial dose distributions were measured using radiochromic translucent poly(vinyl alcohol) cryogels. The cryogels simultaneously served as bolus material, providing the necessary buildup to achieve the desired superficial dose...
April 24, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28436094/dosimetric-validation-of-a-magnetic-resonance-image-gated-radiotherapy-system-using-a-motion-phantom-and-radiochromic-film
#16
James M Lamb, John S Ginn, Dylan P O'Connell, Nzhde Agazaryan, Minsong Cao, David H Thomas, Yingli Yang, Mircea Lazea, Percy Lee, Daniel A Low
PURPOSE: Magnetic resonance image (MRI) guided radiotherapy enables gating directly on the target position. We present an evaluation of an MRI-guided radiotherapy system's gating performance using an MRI-compatible respiratory motion phantom and radiochromic film. Our evaluation is geared toward validation of our institution's clinical gating protocol which involves planning to a target volume formed by expanding 5 mm about the gross tumor volume (GTV) and gating based on a 3 mm window about the GTV...
April 24, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28433589/low-dose-out-of-field-radiotherapy-part-1-measurement-of-scattered-doses
#17
M Kruszyna, S Adamczyk, A Skrobała, M Skórska, W Suchorska, K Zaleska, A Kowalik, W Jackowiak, J Malicki
PURPOSE: To measure out-of-field doses in a phantom model to better quantify this radiation. MATERIAL AND METHODS: The individual contribution of photons and neutrons to the total out-of-field dose for 6 MV and 20 MV photons at open beam were measured in a purpose-designed water phantom. Radiation doses were measured at seven separate points (P1-P7) in the phantom with thermoluminescent detectors (TLD 100, 600, and 700) and GAFchromic™ EBT films. RESULTS: At a prescribed dose of 75Gy to the isocentre, the photon dose level in the close-to-field area (P2) ranged from 2...
April 19, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28395963/dosimetric-impact-assessment-using-a-general-algorithm-in-geant4-simulations-for-a-complex-shaped-multileaf-collimator
#18
Á Perales, M A Cortés-Giraldo, H Miras, R Arráns, M I Gallardo
PURPOSE: We have developed an inhouse algorithm for the multileaf collimator (MLC) geometry model construction with an appropriate accuracy for dosimetric tests. Our purpose is to build a complex type of MLC and analyze the influence of the modeling parameters on the dose calculation. METHODS: Using radiochromic films as detector the following tests were done: (I) Density test field: to compare measured and calculated dose distributions in order to determine the tungsten alloy physical density value...
April 7, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28361478/commissioning-a-hobby-cutting-device-for-radiochromic-film-preparation
#19
Somayeh Zolfaghari, Kirby E Francis, Tanya Kairn, Scott B Crowe
In addition to a high spatial resolution and well characterised dose response, one of the major advantages of radiochromic film as a dosimeter is that sheets of film can be cut into pieces suitable for use as calibration films, and for in vivo and phantom measurements. The cutting of film is typically done using scissors or a guillotine, and this process can be time-consuming, limited in precision, requires extensive handling and does not allow holes to be cut from the film without cutting from an existing edge...
March 30, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28353447/on-the-experimental-validation-of-model-based-dose-calculation-algorithms-for-192-ir-hdr-brachytherapy-treatment-planning
#20
Eleftherios P Pappas, Emmanouil Zoros, Argyris Moutsatsos, Vasiliki Peppa, Kyveli Zourari, Pantelis Karaiskos, Panagiotis Papagiannis
There is an acknowledged need for the design and implementation of physical phantoms appropriate for the experimental validation of model-based dose calculation algorithms (MBDCA) introduced recently in (192)Ir brachytherapy treatment planning systems (TPS), and this work investigates whether it can be met. A PMMA phantom was prepared to accommodate material inhomogeneities (air and Teflon), four plastic brachytherapy catheters, as well as 84 LiF TLD dosimeters (MTS-100M 1  ×  1  ×  1 mm(3) microcubes), two radiochromic films (Gafchromic EBT3) and a plastic 3D dosimeter (PRESAGE)...
May 21, 2017: Physics in Medicine and Biology
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