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Radiochromic film

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https://www.readbyqxmd.com/read/28994669/minibeam-radiotherapy-with-small-animal-irradiators-i-in-vitro-i-and-i-in-vivo-i-feasibility-studies
#1
Soha Bazyar, Christina R Inscoe, E Timothy O'Brien Iii, Otto Z Zhou, Yueh Z Lee
Minibeam radiation therapy (MBRT) delivers ultrahigh dose of X-ray (≥100 Gy) in 200-1000 μm beams (peaks), separated by wider non-irradiated regions (valleys) usually as a single temporal fraction. Preclinical studies performed at synchrotron facilities revealed that MBRT is able to ablate tumors while maintaining normal tissue integrity. The main purpose of present study was to develop an efficient and accessible method to perform MBRT using a conventional X-ray irradiator. We then tested this new method both in-vitro and in-vivo...
October 10, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28974858/volumetric-modulated-arc-therapy-lung-stereotactic-body-radiation-therapy-dosimetric-quality-assurance-a-comparison-between-radiochromic-film-and-chamber-array
#2
Juan Fernando Mata Colodro, Alfredo Serna Berná, Vicente Puchades Puchades, David Ramos Amores, Miguel Alcaraz Baños
INTRODUCTION: The aim of this work is to verify the use of radiochromic film in the quality assurance (QA) of volumetric-modulated arc therapy (VMAT) lung stereotactic body radiation therapy (SBRT) plans and compare the results with those obtained using an ion chamber array. MATERIALS AND METHODS: QA was performed for 14 plans using a two-dimensional-array seven29 and EBT3 film. Dose values per session ranged between 7.5 Gy and 18 Gy. The multichannel method was used to obtain a dose map for film...
July 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/28952964/incidence-of-the-different-sources-of-noise-on-the-uncertainty-in-radiochromic-film-dosimetry-using-single-channel-and-multichannel-methods
#3
Antonio Gonzalez-Lopez, Juan Antonio Vera-Sánchez, Carmen Ruiz-Morales
The incidence of the different sources of noise on the uncertainty in radiochromic film (RCF) dosimetry using single channel and multichannel methods is investigated in this work. These sources of noise are extracted from pixel value (PV) readings and dose maps. Different pieces of a RCF were irradiated to uniform doses ranging from 0 to 1092 cGy. Then, the pieces were read at two resolutions (72 and 150 ppp) with two flatbed scanners: Epson 10000XL and Epson V800, representing two states of technology...
September 27, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28916952/air-electron-stream-interactions-during-magnetic-resonance-igrt-skin-irradiation-outside-the-treatment-field-during-accelerated-partial-breast-irradiation
#4
Jong Min Park, Kyung Hwan Shin, Jung-In Kim, So-Yeon Park, Seung Hyuck Jeon, Noorie Choi, Jin Ho Kim, Hong-Gyun Wu
PURPOSE: To investigate and to prevent irradiation outside the treatment field caused by an electron stream in the air generated by the magnetic field during magnetic resonance image-guided accelerated partial breast irradiation (APBI). MATERIALS AND METHODS: In all, 20 patients who received APBI with a magnetic resonance image-guided radiation therapy (MR-IGRT) system were prospectively studied. The prescription dose was 38.5 Gy in 10 fractions of 3.85 Gy and delivered with a tri-cobalt system (the ViewRay system)...
September 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28915893/dosimetric-comparison-of-different-treatment-modalities-for-stereotactic-radiotherapy
#5
Shih-Ming Hsu, Yuan-Chun Lai, Chien-Chung Jeng, Chia-Ying Tseng
BACKGROUND: The modalities for performing stereotactic radiotherapy (SRT) on the brain include the cone-based linear accelerator (linac), the flattening filter-free (FFF) volumetric modulated arc therapy (VMAT) linac, and tomotherapy. In this study, the cone-based linac, FFF-VMAT linac, and tomotherapy modalities were evaluated by measuring the differences in doses delivered during brain SRT and experimentally assessing the accuracy of the output radiation doses through clinical measurements...
September 16, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28887825/performance-of-a-multi-leaf-collimator-system-for-mr-guided-radiation-therapy
#6
Bin Cai, Harold Li, Deshan Yang, Vivian Rodriguez, Austen Curcuru, Yuhe Wang, Jie Wen, Rojano Kashani, Sasa Mutic, Olga Green
PURPOSE: To investigate and characterize the performance of a Multi Leaf Collimator (MLC) designed for Cobalt-60 based MR-guided radiation therapy system in a 0.35T magnetic field. METHODS: The MLC design and unique assembly features in the ViewRay MRIdian system were first reviewed. The RF cage shielding of MLC motor and cables were evaluated using ACR phantoms with real time imaging and quantified by signal-to-noise ratio. The dosimetric characterizations, including the leaf transmission, leaf penumbra, tongue and groove effect, were investigated using radiosensitive films...
September 9, 2017: Medical Physics
https://www.readbyqxmd.com/read/28869164/the-output-factor-correction-as-function-of-the-photon-beam-field-size-direct-measurement-and-calculation-from-the-lateral-dose-response-functions-of-gas-filled-and-solid-detectors
#7
Daniela Poppinga, Björn Delfs, Jutta Meyners, Dietrich Harder, Björn Poppe, Hui Khee Looe
The first aim of this study has been to extend the systematic experimental study of the field size dependence of the output factor correction for three micro-ionization chambers (PTW 31014, PTW 31022 and IBA Razor chamber), two silicon diodes (PTW 60017 and IBA Razor Diode) and the synthetic diamond detector microDiamond (PTW 60019) in a 6 MV photon beam down to an effective field side length of 2.6mm, and to summarize the present knowledge of this factor by treating it as a function of the dosimetric field size...
August 28, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28827006/intraoperative-implantation-of-a-mesh-of-directional-palladium-sources-civasheet-dosimetry-verification-clinical-commissioning-dose-specification-and-preliminary-experience
#8
Gil'ad N Cohen, Karen Episcopia, Seng-Boh Lim, Thomas J LoSasso, Mark J Rivard, Amandeep S Taggar, Neil K Taunk, Abraham J Wu, Antonio L Damato
PURPOSE: To present the clinical commissioning of a novel (103)Pd directional brachytherapy device (CivaSheet) for intraoperative radiation therapy. METHODS AND MATERIALS: Clinical commissioning for the CivaSheet consisted of establishing: (1) source strength calibration capabilities, (2) experimental verification of TG-43 dosimetry parameters, (3) treatment planning system validation, and (4) departmental practice for dose specification and source ordering. Experimental verification was performed in water with radiochromic film calibrated with a 37 kVp X-ray beam...
August 18, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28816146/quality-assessment-of-stereotactic-radiosurgery-of-a-melanoma-brain-metastases-model-using-a-mouselike-phantom-and-the-small-animal-radiation-research-platform
#9
Cheng-Chia Wu, Kunal R Chaudhary, Yong Hum Na, David Welch, Paul J Black, Adam M Sonabend, Peter Canoll, Yvonne M Saenger, Tony J C Wang, Cheng-Shie Wuu, Tom K Hei, Simon K Cheng
PURPOSE: To establish a novel preclinical model for stereotactic radiosurgery (SRS) with combined mouselike phantom quality assurance in the setting of brain metastases. METHODS AND MATERIALS: C57B6 mice underwent intracranial injection of B16-F10 melanoma cells. T1-weighted postcontrast magnetic resonance imaging (MRI) was performed on day 11 after injection. The MRI images were fused with cone beam computed tomography (CBCT) images using the Small Animal Radiation Research Platform (SARRP)...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28750023/the-combination-of-the-error-correction-methods-of-gafchromic-ebt3-film
#10
Yinghui Li, Lixin Chen, Jinhan Zhu, Xiaowei Liu
PURPOSE: The aim of this study was to combine a set of methods for use of radiochromic film dosimetry, including calibration, correction for lateral effects and a proposed triple-channel analysis. These methods can be applied to GAFCHROMIC EBT3 film dosimetry for radiation field analysis and verification of IMRT plans. METHODS: A single-film exposure was used to achieve dose calibration, and the accuracy was verified based on comparisons with the square-field calibration method...
2017: PloS One
https://www.readbyqxmd.com/read/28735877/dose-comparison-between-tg-43-based-calculations-and-radiochromic-film-measurements-of-the-freiburg-flap-applicator-used-for-high-dose-rate-brachytherapy-treatments-of-skin-lesions
#11
Saad Aldelaijan, Hamed Bekerat, Ivan Buzurovic, Phillip Devlin, Francois DeBlois, Jan Seuntjens, Slobodan Devic
PURPOSE: Current high-dose-rate brachytherapy skin treatments with the Freiburg flap (FF) applicator are planned with treatment planning systems based on the American Association of Physicists in Medicine TG-43 data sets, which assume full backscatter conditions in dose calculations. The aim of this work is to describe an experimental method based on radiochromic film dosimetry to evaluate dose calculation accuracy during surface treatments with the FF applicator at different depths and bolus thicknesses...
July 20, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28715250/the-development-of-technology-for-effective-respiratory-gated-irradiation-using-an-image-guided-small-animal-irradiator
#12
M A Hill, J M Thompson, A Kavanagh, I D C Tullis, R G Newman, J Prentice, J Beech, S Gilchrist, S Smart, E Fokas, B Vojnovic
The development of image-guided small animal irradiators represents a significant improvement over standard irradiators by enabling preclinical studies to mimic radiotherapy in humans. The ability to deliver tightly collimated targeted beams, in conjunction with gantry or animal couch rotation, has the potential to maximize tumor dose while sparing normal tissues. However, the current commercial platforms do not incorporate respiratory gating, which is required for accurate and precise targeting in organs subject to respiration related motions that may be up to the order of 5 mm in mice...
September 2017: Radiation Research
https://www.readbyqxmd.com/read/28711183/fast-protocol-for-radiochromic-film-dosimetry-using-a-cloud-computing-web-application
#13
Juan-Francisco Calvo-Ortega, Miquel Pozo, Sandra Moragues, Joan Casals
PURPOSE: To investigate the feasibility of a fast protocol for radiochromic film dosimetry to verify intensity-modulated radiotherapy (IMRT) plans. METHOD AND MATERIALS: EBT3 film dosimetry was conducted in this study using the triple-channel method implemented in the cloud computing application (Radiochromic.com). We described a fast protocol for radiochromic film dosimetry to obtain measurement results within 1h. Ten IMRT plans were delivered to evaluate the feasibility of the fast protocol...
July 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28691256/clinical-usefulness-of-mlcs-in-robotic-radiosurgery-systems-for-prostate-sbrt
#14
Masashi Tomida, Takeshi Kamomae, Junji Suzuki, Yoichi Ohashi, Yoshiyuki Itoh, Hiroshi Oguchi, Takahito Okuda
Stereotactic body radiation therapy (SBRT) using recently introduced multileaf collimators (MLC) is preferred over circular collimators in the treatment of localized prostate cancer. The objective of this study was to assess the clinical usefulness of MLCs in prostate SBRT by comparing the effectiveness of treatment plans using fixed collimators, variable collimators, and MLCs and by ensuring delivery quality assurance (DQA) for each. For each patient who underwent conventional radiation therapy for localized prostate cancer, mock SBRT plans were created using a fixed collimator, a variable collimator, and an MLC...
July 10, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28671885/effects-of-the-metallic-port-in-tissue-expanders-on-dose-distribution-in-postmastectomy-radiotherapy-a-tridimensional-experimental-model-of-dosimetry-in-breast-reconstruction
#15
Marcelo Felix da Silva, Harley Francisco de Oliveira, Leandro Frederich Borges, Helio Humberto Angotti Carrara, Jayme Adriano Farina
The purpose of this research was to develop an experimental model of dosimetry using a breast phantom and evaluate the effects of the metallic port in tissue expanders on dose distribution in postmastectomy radiotherapy. Dose distribution was assessed using an experimental acrylic dosimetry simulator in the absence and presence of a metallic disc (MD), which is similar to that used in tissue expanders containing a magnetic port, by collecting coronal and sagittal radiochromic films. Dosimetry film analysis did not show any changes in dose distribution, except for a MD shadow in the sagittal film where the dose distribution rate was on average 14% lower than in other areas...
June 1, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28666767/towards-breast-cancer-rotational-radiotherapy-with-synchrotron-radiation
#16
Francesca Di Lillo, Giovanni Mettivier, Antonio Sarno, Roberta Castriconi, Paolo Russo
PURPOSE: We performed the first investigations, via measurements and Monte Carlo simulations on phantoms, of the feasibility of a new technique for synchrotron radiation rotational radiotherapy for breast cancer (SR(3)T). METHODS: A Monte Carlo (MC) code based on Geant4 toolkit was developed in order to simulate the irradiation with the SR(3)T technique and to evaluate the skin sparing effect in terms of centre-to-periphery dose ratio at different energies in the range 60-175keV...
June 27, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28620561/patient-specific-qa-of-spot-scanning-proton-beams-using-radiochromic-film
#17
Maria F Chan, Chin-Cheng Chen, Chengyu Shi, Jingdong Li, Xiaoli Tang, Xiang Li, Dennis Mah
Radiochromic film for spot-scanning QA provides high spatial resolution and efficiency gains from one-shot irradiation for multiple depths. However, calibration can be a tedious procedure which may limit widespread use. Moreover, since there may be an energy dependence, which manifests as a depth dependence, this may require additional measurements for each patient. We present a one-scan protocol to simplify the procedure. A calibration using an EBT3 film, exposed by a 6-level step-wedge plan on a Proteus(®)PLUS proton system (IBA, Belgium), was performed at depths of 18, 20, 24cm using Plastic Water(®) (CIRS, Norfolk, VA)...
May 2017: International journal of medical physics, clinical engineering and radiation oncology
https://www.readbyqxmd.com/read/28578699/treating-lung-cancer-with-dynamic-conformal-arc-therapy-a-dosimetric-study
#18
Primož Peterlin, Karmen Stanič, Ignasi Méndez, Andrej Strojnik
BACKGROUND: Lung cancer patients are often in poor physical condition, and a shorter treatment time would reduce their discomfort. Dynamic conformal arc therapy (DCAT) offers a shorter treatment time than conventional 3D conformal radiotherapy (3D CRT) and is usually available even in departments without inverse planning possibilities. We examined its suitability as a treatment modality for lung cancer patients. METHODS: On a cohort of 35 lung cancer patients, relevant dosimetric parameters were compared in respective DCAT and 3D CRT treatment plans...
June 2, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28574219/optimization-of-the-dosimetric-leaf-gap-for-use-in-planning-vmat-treatments-of-spine-sabr-cases
#19
Nigel D Middlebrook, Bess Sutherland, Tanya Kairn
The dosimetric leaf gap (DLG) is a beam configuration parameter used in the Varian Eclipse treatment planning system, to model the effects of rounded MLC leaf ends. Measuring the DLG using the conventional sliding-slit technique has been shown to be produce questionable results for some volumetric modulated arc therapy (VMAT) treatments. This study therefore investigated the use of radiochromic film measurements to optimize the DLG specifically for the purpose of producing accurate VMAT plans using a flattening-filter-free (FFF) beam, for use in treating vertebral targets using a stereotactic (SABR, also known as SBRT) fractionation schedule...
June 2, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28574149/measurement-of-uv-emission-from-a-diffusing-optical-fiber-using-radiochromic-film
#20
David Welch, Henry M Spotnitz, David J Brenner
Analysis of the emission pattern from optical diffuser tips is vital to their usage in biomedical applications, especially as they find growing functionality beyond established phototherapy techniques. The use of ultraviolet radiation with diffuser tips increases the need to accurately characterize these devices, both for effective application and to avoid potentially dangerous exposure conditions. This study presents a new method to capture the diffusion pattern at a high resolution through the use of radiochromic film...
June 2, 2017: Photochemistry and Photobiology
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